- Smilow Cancer Hospital at Yale New Haven35 Park StreetNew Haven, CT 06511
Philippos Costa, MD
Sarcoma, Medical Oncology
Patient type treated
Adult
Accepting new patients
Yes
Referral required
Not Applicable
Board Certified in
Internal Medicine
Titles
- Assistant Professor of Medicine (Medical Oncology and Hematology)
- Scientific-Advisor, Medical Oncology, Associação Tumor Desmoide Brasil
Education & Training
- MSYale, Internal Medicine (2025)
- Internal MedicineUniversity of Miami (2022)
- Internal MedicineUniversidade Federal de Uberlândia: (2018)
- MDUniversidade Federal do Vale do São Francisco, Medicine (2016)
Languages Spoken
- English
- Português (Portuguese)
- Español (Spanish)
Additional Information
Honors & Recognitions
- The Vanessa Blumer Research Scholar Award: (2022)
Board Certifications
- AB of Internal Medicine, Internal Medicine (2022)
Professional Service
- Managed Health Care (2022 - Present): Featured in magazine article entitled “Black Lung Cancer Patients May Be Missing Out On Era of Targeted Therapy” based on the work “Prevalence of Targetable Mutations in Black Patients"
- GIST Journal (2021 - Present): Reviewer
- Connective Tissue Oncology Society (CTOS) (2019 - Present): Member
- American Society of Clinical Oncology (ASCO) (2018 - Present): Member
- American College of Physicians (ACP) (2018 - Present): Member
- Sociedade Brasileira de Oncologia Clínica (SBOC) (2018 - Present): Member
Publications
- Hardy N, Frej K, Nkansah R, Olino K, Deshpande H, Ma X, Trent J, Costa P. Twenty‐five years without progress: The enduring challenge of soft tissue sarcomas. Cancer 2025, 131: e35906. PMID: 40396557, DOI: 10.1002/cncr.35906.
- Costa PA, Menezes C, Bianca Lopes David B, Garofalo G, Prudente Barbieri L, Campos F. Enhancing rare cancer care in developing countries through patient advocacy: insights from the Desmoid Tumor Brazilian Association. Ther Adv Med Oncol 2025, 17: 17588359241309827. PMID: 39801613, DOI: 10.1177/17588359241309827.
- Costa P, Arora A, Fernandez Y, Yi I, Bakkila B, Tan H, Coelho P, Campoverde L, Hardy N, Bialick S, Freire A, D’Amato G, Chang Y, Mesenger J, Subhawong T, Haims A, Hurwitz M, Olino K, Turaga K, Deshpande H, Trent J. Sorafenib or anthracycline‐based chemotherapy for progressive desmoid tumors. Cancer 2024, 131: e35647. PMID: 39543805, DOI: 10.1002/cncr.35647.
- Noujaim J, Gupta AA, Holloway CL, Saleh R, Srikanthan A, Lemieux C, Soroka HP, Tibout P, Turcotte R, Feng X, Abdul Razak AR, Costa P. Real-word experience of pazopanib and sorafenib in patients with desmoid tumors: A CanSaRCC multi-center study. Eur J Cancer 2024, 205: 114119. PMID: 38759389, DOI: 10.1016/j.ejca.2024.114119.
- Costa PA, Tse DT, Benedetto P. Neoadjuvant Intra-arterial Cytoreductive Chemotherapy Improves Outcomes in Lacrimal Gland Adenoid Cystic Carcinoma. Oncologist 2024, 29: 263-269. PMID: 38227581, DOI: 10.1093/oncolo/oyad346.
- Souza FF, D'Amato G, Jonczak EE, Costa P, Trent JC, Rosenberg AE, Yechieli R, Temple HT, Pattany P, Subhawong TK. MRI T2 mapping assessment of T2 relaxation time in desmoid tumors as a quantitative imaging biomarker of tumor response: preliminary results. Front Oncol 2023, 13: 1286807. PMID: 38188297, DOI: 10.3389/fonc.2023.1286807.
- O'Neil DS, Martei YM, Crew KD, Castillo BS, Costa P, Lim T, Michel A, Rubin E, Goel N, Hurley J, Lopes G, Antoni MH. Time to Cancer Treatment and Chemotherapy Relative Dose Intensity for Patients With Breast Cancer Living With HIV. JAMA Netw Open 2023, 6: e2346223. PMID: 38051529, DOI: 10.1001/jamanetworkopen.2023.46223.
- Yan CL, Costa PA, Wu Y. Acute pancreatitis from a delayed haemolytic transfusion reaction. Transfus Med 2022, 32: 522-524. PMID: 36056461, DOI: 10.1111/tme.12912.
- Barreto-Coelho P, Rosenberg A, Subhawong T, Costa P, Espejo-Freire AP, Bialick S, Jonczak E, Trent JC, D'Amato GZ. Treatment of Disseminated Intravenous Leiomyomatosis With ALK Targeting Crizotinib: A Successful Case Report. JCO Precision Oncology 2022, 6: e2100336. PMID: 35108034, DOI: 10.1200/PO.21.00336.
- Costa PA, Espejo-Freire AP, Fan KC, Albini TA, Pongas G. Panuveitis induced by brentuximab vedotin: a possible novel adverse event of an antibody-drug conjugate. Leukemia & Lymphoma 2022, 63: 239-242. PMID: 34514943, DOI: 10.1080/10428194.2021.1978090.
- Minjares RO, Aguirre LE, Costa PA, Montoya-Cerrillo DM, Goldberg DS. Primary Jejunal GIST in a Patient with Phakomatosis: An Atypical Source of Massive Gastrointestinal Hemorrhage Associated with RASopathy. Gastrointestinal Stromal Tumor 2022. doi: 10.21037/gist-21-13
- Costa PA, Marbin S, Costa BMLA, Espejo-Freire AP, Saul EE, Barreto-Coelho P, Allen A, Hakim MO, Goel N, D'Amato GZ, Subhawong T, Trent JC. A nonrandom association of breast implants and the formation of desmoid tumors. The Breast Journal 2021, 27: 768-775. PMID: 34453383, DOI: 10.1111/tbj.14276.
- Espejo-Freire AP, Elliott A, Rosenberg A, Costa PA, Barreto-Coelho P, Jonczak E, D'Amato G, Subhawong T, Arshad J, Diaz-Perez JA, Korn WM, Oberley MJ, Magee D, Dizon D, von Mehren M, Khushman MM, Hussein AM, Leu K, Trent JC. Genomic Landscape of Angiosarcoma: A Targeted and Immunotherapy Biomarker Analysis. Cancers 2021, 13 PMID: 34638300, PMCID: PMC8507700, DOI: 10.3390/cancers13194816.
- Arshad J, Costa PA, Barreto-Coelho P, Valdes BN, Trent JC. Immunotherapy Strategies for Gastrointestinal Stromal Tumor. Cancers 2021, 13 PMID: 34298737, PMCID: PMC8306810, DOI: 10.3390/cancers13143525.
- Costa PA, Costa BMLA, Rozenbaum G, Barreto-Coelho P. Anti-Ma paraneoplastic opsoclonus-myoclonus syndrome. BMJ Case Reports 2021, 14 PMID: 33975854, PMCID: PMC8117984, DOI: 10.1136/bcr-2021-243136.
- Costa PA, Saul EE, Paul Y, Iyer S, da Silva LL, Tamariz L, Lopes G. Prevalence of Targetable Mutations in Black Patients With Lung Cancer: A Systematic Review and Meta-Analysis. JCO Oncology Practice 2021, 17: e629-e636. PMID: 33974815, DOI: 10.1200/OP.20.00961.
- Barreto-Coelho P., Costa PA, Espejo-Freire A., Jonczak E., D’Amato G., Trent J.C. Advanced and Metastatic GIST: Review of Current Knowledge and Latest Advances 2021; touchONCOLOGY.
- Costa PA, Hana CKA, Chakravarthy N, Skryd AF, Valdes BN, Barreto-Coelho P, Minjares RO, Espejo-Freire A, Hakim MO, Jonczak E, Subhawong T, Livingstone A, Trent JC, D’Amato GZ. Dose Escalation of Ripretinib can Lead to Response in Advanced Gastrointestinal Stromal Tumors Refractory to the Standard Dose: A Report of Two Cases. Gastrointestinal Stromal Tumor. DOI: 10.21037/gist-21-1
- Costa PA, Costa BMLA, Milikowski C, St Onge JE. Acute generalised exanthematous pustulosis associated with shock. BMJ Case Reports 2020, 13 PMID: 33127730, PMCID: PMC7604797, DOI: 10.1136/bcr-2020-235846.
- Costa PA, Needelman BS, Tjendra Y, Hoffman JE. High-grade B-cell lymphoma with MYC and BCL6 rearrangements presenting as a cervical mass. BMJ Case Reports 2020, 13 PMID: 32843454, PMCID: PMC7449310, DOI: 10.1136/bcr-2020-235451.
- Ferreira Junior EG, Costa PA, Freire Golveia Silveira LM, Pertile Salvioni NC, Loureiro BM, Lodi Peres SL, Pereira TJ. Transhiatal esophagectomy with gastric pull-up, pyloric exclusion and Roux-en-Y gastroenterostomy for the management of esophageal caustic injury. International Journal Of Surgery Case Reports 2019, 56: 66-69. PMID: 30831510, PMCID: PMC6403175, DOI: 10.1016/j.ijscr.2019.02.006.
- Ferreira Junior EG, Apolinario Costa P, Freire Golveia Silveira LM, Valois Vieira R, Lima Martins Soares HA, Menon Loureiro B, Pertile Salvioni NC, Coelho Ferreira Rocha JR. Localized pancreatic Castleman disease presenting with extrahepatic dilatation of bile ducts: A case report and review of published cases. International Journal Of Surgery Case Reports 2019, 54: 28-33. PMID: 30513495, PMCID: PMC6279997, DOI: 10.1016/j.ijscr.2018.11.006.
- Desmoplastic small-round-cell tumorCosta PA, Reis WG, Loureiro BM, Ferreira Junior EG, Rocha JRCF, Alencar KMSA. Revista Brasileira De Cancerologia, 2018, Dec; 64(4), 573-577.
Departments and Programs
Locations
- Smilow Cancer Hospital at Yale New Haven35 Park StreetNew Haven, CT 06511
Titles
- Assistant Professor of Medicine (Medical Oncology and Hematology)
- Scientific-Advisor, Medical Oncology, Associação Tumor Desmoide Brasil
Education & Training
- MSYale, Internal Medicine (2025)
- Internal MedicineUniversity of Miami (2022)
- Internal MedicineUniversidade Federal de Uberlândia: (2018)
- MDUniversidade Federal do Vale do São Francisco, Medicine (2016)
Languages Spoken
- English
- Português (Portuguese)
- Español (Spanish)
Additional Information
Honors & Recognitions
- The Vanessa Blumer Research Scholar Award: (2022)
Board Certifications
- AB of Internal Medicine, Internal Medicine (2022)
Professional Service
- Managed Health Care (2022 - Present): Featured in magazine article entitled “Black Lung Cancer Patients May Be Missing Out On Era of Targeted Therapy” based on the work “Prevalence of Targetable Mutations in Black Patients"
- GIST Journal (2021 - Present): Reviewer
- Connective Tissue Oncology Society (CTOS) (2019 - Present): Member
- American Society of Clinical Oncology (ASCO) (2018 - Present): Member
- American College of Physicians (ACP) (2018 - Present): Member
- Sociedade Brasileira de Oncologia Clínica (SBOC) (2018 - Present): Member
Publications
- Hardy N, Frej K, Nkansah R, Olino K, Deshpande H, Ma X, Trent J, Costa P. Twenty‐five years without progress: The enduring challenge of soft tissue sarcomas. Cancer 2025, 131: e35906. PMID: 40396557, DOI: 10.1002/cncr.35906.
- Costa PA, Menezes C, Bianca Lopes David B, Garofalo G, Prudente Barbieri L, Campos F. Enhancing rare cancer care in developing countries through patient advocacy: insights from the Desmoid Tumor Brazilian Association. Ther Adv Med Oncol 2025, 17: 17588359241309827. PMID: 39801613, DOI: 10.1177/17588359241309827.
- Costa P, Arora A, Fernandez Y, Yi I, Bakkila B, Tan H, Coelho P, Campoverde L, Hardy N, Bialick S, Freire A, D’Amato G, Chang Y, Mesenger J, Subhawong T, Haims A, Hurwitz M, Olino K, Turaga K, Deshpande H, Trent J. Sorafenib or anthracycline‐based chemotherapy for progressive desmoid tumors. Cancer 2024, 131: e35647. PMID: 39543805, DOI: 10.1002/cncr.35647.
- Noujaim J, Gupta AA, Holloway CL, Saleh R, Srikanthan A, Lemieux C, Soroka HP, Tibout P, Turcotte R, Feng X, Abdul Razak AR, Costa P. Real-word experience of pazopanib and sorafenib in patients with desmoid tumors: A CanSaRCC multi-center study. Eur J Cancer 2024, 205: 114119. PMID: 38759389, DOI: 10.1016/j.ejca.2024.114119.
- Costa PA, Tse DT, Benedetto P. Neoadjuvant Intra-arterial Cytoreductive Chemotherapy Improves Outcomes in Lacrimal Gland Adenoid Cystic Carcinoma. Oncologist 2024, 29: 263-269. PMID: 38227581, DOI: 10.1093/oncolo/oyad346.
- Souza FF, D'Amato G, Jonczak EE, Costa P, Trent JC, Rosenberg AE, Yechieli R, Temple HT, Pattany P, Subhawong TK. MRI T2 mapping assessment of T2 relaxation time in desmoid tumors as a quantitative imaging biomarker of tumor response: preliminary results. Front Oncol 2023, 13: 1286807. PMID: 38188297, DOI: 10.3389/fonc.2023.1286807.
- O'Neil DS, Martei YM, Crew KD, Castillo BS, Costa P, Lim T, Michel A, Rubin E, Goel N, Hurley J, Lopes G, Antoni MH. Time to Cancer Treatment and Chemotherapy Relative Dose Intensity for Patients With Breast Cancer Living With HIV. JAMA Netw Open 2023, 6: e2346223. PMID: 38051529, DOI: 10.1001/jamanetworkopen.2023.46223.
- Yan CL, Costa PA, Wu Y. Acute pancreatitis from a delayed haemolytic transfusion reaction. Transfus Med 2022, 32: 522-524. PMID: 36056461, DOI: 10.1111/tme.12912.
- Barreto-Coelho P, Rosenberg A, Subhawong T, Costa P, Espejo-Freire AP, Bialick S, Jonczak E, Trent JC, D'Amato GZ. Treatment of Disseminated Intravenous Leiomyomatosis With ALK Targeting Crizotinib: A Successful Case Report. JCO Precision Oncology 2022, 6: e2100336. PMID: 35108034, DOI: 10.1200/PO.21.00336.
- Costa PA, Espejo-Freire AP, Fan KC, Albini TA, Pongas G. Panuveitis induced by brentuximab vedotin: a possible novel adverse event of an antibody-drug conjugate. Leukemia & Lymphoma 2022, 63: 239-242. PMID: 34514943, DOI: 10.1080/10428194.2021.1978090.
- Minjares RO, Aguirre LE, Costa PA, Montoya-Cerrillo DM, Goldberg DS. Primary Jejunal GIST in a Patient with Phakomatosis: An Atypical Source of Massive Gastrointestinal Hemorrhage Associated with RASopathy. Gastrointestinal Stromal Tumor 2022. doi: 10.21037/gist-21-13
- Costa PA, Marbin S, Costa BMLA, Espejo-Freire AP, Saul EE, Barreto-Coelho P, Allen A, Hakim MO, Goel N, D'Amato GZ, Subhawong T, Trent JC. A nonrandom association of breast implants and the formation of desmoid tumors. The Breast Journal 2021, 27: 768-775. PMID: 34453383, DOI: 10.1111/tbj.14276.
- Espejo-Freire AP, Elliott A, Rosenberg A, Costa PA, Barreto-Coelho P, Jonczak E, D'Amato G, Subhawong T, Arshad J, Diaz-Perez JA, Korn WM, Oberley MJ, Magee D, Dizon D, von Mehren M, Khushman MM, Hussein AM, Leu K, Trent JC. Genomic Landscape of Angiosarcoma: A Targeted and Immunotherapy Biomarker Analysis. Cancers 2021, 13 PMID: 34638300, PMCID: PMC8507700, DOI: 10.3390/cancers13194816.
- Arshad J, Costa PA, Barreto-Coelho P, Valdes BN, Trent JC. Immunotherapy Strategies for Gastrointestinal Stromal Tumor. Cancers 2021, 13 PMID: 34298737, PMCID: PMC8306810, DOI: 10.3390/cancers13143525.
- Costa PA, Costa BMLA, Rozenbaum G, Barreto-Coelho P. Anti-Ma paraneoplastic opsoclonus-myoclonus syndrome. BMJ Case Reports 2021, 14 PMID: 33975854, PMCID: PMC8117984, DOI: 10.1136/bcr-2021-243136.
- Costa PA, Saul EE, Paul Y, Iyer S, da Silva LL, Tamariz L, Lopes G. Prevalence of Targetable Mutations in Black Patients With Lung Cancer: A Systematic Review and Meta-Analysis. JCO Oncology Practice 2021, 17: e629-e636. PMID: 33974815, DOI: 10.1200/OP.20.00961.
- Barreto-Coelho P., Costa PA, Espejo-Freire A., Jonczak E., D’Amato G., Trent J.C. Advanced and Metastatic GIST: Review of Current Knowledge and Latest Advances 2021; touchONCOLOGY.
- Costa PA, Hana CKA, Chakravarthy N, Skryd AF, Valdes BN, Barreto-Coelho P, Minjares RO, Espejo-Freire A, Hakim MO, Jonczak E, Subhawong T, Livingstone A, Trent JC, D’Amato GZ. Dose Escalation of Ripretinib can Lead to Response in Advanced Gastrointestinal Stromal Tumors Refractory to the Standard Dose: A Report of Two Cases. Gastrointestinal Stromal Tumor. DOI: 10.21037/gist-21-1
- Costa PA, Costa BMLA, Milikowski C, St Onge JE. Acute generalised exanthematous pustulosis associated with shock. BMJ Case Reports 2020, 13 PMID: 33127730, PMCID: PMC7604797, DOI: 10.1136/bcr-2020-235846.
- Costa PA, Needelman BS, Tjendra Y, Hoffman JE. High-grade B-cell lymphoma with MYC and BCL6 rearrangements presenting as a cervical mass. BMJ Case Reports 2020, 13 PMID: 32843454, PMCID: PMC7449310, DOI: 10.1136/bcr-2020-235451.
- Ferreira Junior EG, Costa PA, Freire Golveia Silveira LM, Pertile Salvioni NC, Loureiro BM, Lodi Peres SL, Pereira TJ. Transhiatal esophagectomy with gastric pull-up, pyloric exclusion and Roux-en-Y gastroenterostomy for the management of esophageal caustic injury. International Journal Of Surgery Case Reports 2019, 56: 66-69. PMID: 30831510, PMCID: PMC6403175, DOI: 10.1016/j.ijscr.2019.02.006.
- Ferreira Junior EG, Apolinario Costa P, Freire Golveia Silveira LM, Valois Vieira R, Lima Martins Soares HA, Menon Loureiro B, Pertile Salvioni NC, Coelho Ferreira Rocha JR. Localized pancreatic Castleman disease presenting with extrahepatic dilatation of bile ducts: A case report and review of published cases. International Journal Of Surgery Case Reports 2019, 54: 28-33. PMID: 30513495, PMCID: PMC6279997, DOI: 10.1016/j.ijscr.2018.11.006.
- Desmoplastic small-round-cell tumorCosta PA, Reis WG, Loureiro BM, Ferreira Junior EG, Rocha JRCF, Alencar KMSA. Revista Brasileira De Cancerologia, 2018, Dec; 64(4), 573-577.
Departments and Programs
Locations
- Smilow Cancer Hospital at Yale New Haven35 Park StreetNew Haven, CT 06511
- Smilow Cancer Hospital at Yale New Haven35 Park StreetNew Haven, CT 06511