Michael Hurwitz, MD, PhD
Medical Oncology
Biography
Michael Hurwitz, MD, PhD, is a medical oncologist who cares for people with genitourinary cancers, including kidney, bladder, prostate, and testicular cancers. He uses immune cell-based therapies to treat a wide range of solid tumors.
“As a clinician, my goal is to provide the best clinical care to my patients,” Dr. Hurwitz says. “To do that, I think it is paramount to address patients’ goals and desires.”
As an associate professor of medicine (medical oncology) at Yale School of Medicine, Dr. Hurwitz focuses on expanding clinical trials for immune cell-based treatments. He collaborates with scientists to develop new approaches for improving outcomes in kidney and other solid tumor cancers. He is also the co-director of the Cell Therapy Clinical Research Program at Yale Cancer Center.
Dr. Hurwitz received his medical degree from Cornell University Medical College and earned a doctoral degree from Rockefeller University. He completed a residency in internal medicine at The NewYork-Presbyterian Hospital/Weill Cornell Medical Center, followed by a fellowship in adult oncology at Dana-Farber Cancer Institute, Brigham and Women’s Hospital, and Massachusetts General Hospital.
Titles
- Associate Professor of Internal Medicine (Medical Oncology)
- Program Director, Hematology/Oncology Fellowship Program
Education & Training
- Postdoctoral FellowMassachusetts Institute of Technology (2010)
- FellowDana-Farber Cancer Institute/Brigham and Women's Hospital/Massachusetts General Hospital (2004)
- Resident in MedicineThe New York Presbyterian Hospital - Weill Cornell Campus (2000)
- MDCornell University Medical College (1998)
- PhDRockefeller University (1997)
- ABHarvard College, Biochemical Sciences (1991)
Additional Information
Honors & Recognitions
- Medical Oncology Teaching Award: Yale Cancer Center (2024)
- Medical Oncology Teaching Award: Yale Medical Oncology and Hematology Fellowship Program (2015), (2023)
Publications
- Coppola G, Kerr S, Cha P, Bersenev A, Olino K, Kluger H, Sznol M, Weiss S, Bosenberg M, Kleinstein S, Krause D, Hurwitz M, Katz S. Ex vivo expansion of melanoma tumor infiltrating lymphocytes leads to a dominant exhausted T cell population with lack of memory markers. Cancer Immunology Research 2026, 14: 861-874. PMID: 41686210, PMCID: PMC13032746, DOI: 10.1158/2326-6066.cir-25-0798.
- Savion-Gaiger N, Considine B, Hasson N, Nelson M, Chiang V, Kluger H, Braun D, Schoenfeld D, Sznol M, Leapman M, Hurwitz M. Survival of patients with metastatic renal cell carcinoma with or without brain metastases. The Oncologist 2025, 30: oyaf387. PMID: 41287461, PMCID: PMC12704413, DOI: 10.1093/oncolo/oyaf387.
- Gaiger N, Hurwitz M, Hafez N, Kluger H, Herold K, Perdigoto A. Immune checkpoint inhibitor-induced diabetes can potentially be effectively treated with infliximab: a case report of two patients. Frontiers In Endocrinology 2025, 16: 1697724. PMID: 41282287, PMCID: PMC12634352, DOI: 10.3389/fendo.2025.1697724.
- Aizenbud L, Gaiger N, Perdigoto A, Mann J, Torres M, Boland G, Lawless A, Silverman S, Schoenfeld D, Destina J, Hasson N, Tran T, Hurwitz M, Austin M, Sullivan R, Herold K, Kluger H. Factors that increase class I MHC expression may contribute to the development of immune checkpoint inhibitor-induced diabetes. Journal For ImmunoTherapy Of Cancer 2025, 13: e012358. PMID: 40935567, PMCID: PMC13059913, DOI: 10.1136/jitc-2025-012358.
- McManus H, Long J, Westvold S, Leapman M, Hurwitz M, Mitchell A, Pollack C, Gross C, Dinan M. Off-Label Use of First-Line Immunotherapy for Metastatic Renal Cell Carcinoma. Clinical Genitourinary Cancer 2025, 23: 102330. PMID: 40186898, PMCID: PMC12084128, DOI: 10.1016/j.clgc.2025.102330.
- Hugaboom M, Wirth L, Street K, Ruthen N, Jegede O, Schindler N, Shah V, Zaemes J, El Ahmar N, Matar S, Savla V, Choueiri T, Denize T, West D, McDermott D, Plimack E, Sosman J, Haas N, Stein M, Alter R, Bilen M, Hurwitz M, Hammers H, Signoretti S, Atkins M, Wu C, Braun D. Presence of Tertiary Lymphoid Structures and Exhausted Tissue-Resident T Cells Determines Clinical Response to PD-1 Blockade in Renal Cell Carcinoma. Cancer Discovery 2025, 15: 948-968. PMID: 39992403, PMCID: PMC12048281, DOI: 10.1158/2159-8290.cd-24-0991.
- Xu W, Birch G, Meliki A, Moritz V, Bharadwaj M, Schindler N, Labaki C, Saliby R, Dinh K, Horst J, Sun M, Kashima S, Hugaboom M, Dighe A, Machaalani M, Lee G, Hurwitz M, McGregor B, Hirsch M, Shukla S, McDermott D, Signoretti S, Romee R, Choueiri T, Braun D. Progressive natural killer cell dysfunction in advanced-stage clear-cell renal cell carcinoma and association with clinical outcomes. ESMO Open 2025, 10: 104105. PMID: 39813824, PMCID: PMC11783098, DOI: 10.1016/j.esmoop.2024.104105.
- Schoenfeld D, Djureinovic D, Su D, Zhang L, Lu B, Kamga L, Mann J, Huck J, Hurwitz M, Braun D, Jilaveanu L, Ring A, Kluger H. Decoy-resistant IL-18 reshapes the tumor microenvironment and enhances rejection by anti-CTLA-4 in renal cell carcinoma. JCI Insight 2024, 10: e184545. PMID: 39561007, PMCID: PMC11721305, DOI: 10.1172/jci.insight.184545.
- Costa P, Arora A, Fernandez Y, Yi I, Bakkila B, Tan H, Coelho P, Campoverde L, Hardy N, Bialick S, Freire A, D’Amato G, Chang Y, Mesenger J, Subhawong T, Haims A, Hurwitz M, Olino K, Turaga K, Deshpande H, Trent J. Sorafenib or anthracycline‐based chemotherapy for progressive desmoid tumors. Cancer 2024, 131: e35647. PMID: 39543805, DOI: 10.1002/cncr.35647.
- Forman R, Long J, Westvold S, Agnish K, McManus H, Leapman M, Hurwitz M, Spees L, Wheeler S, Gross C, Dinan M. Cost trends of metastatic renal cell carcinoma therapy: the impact of oral anticancer agents and immunotherapy. JNCI Cancer Spectrum 2024, 8: pkae067. PMID: 39133171, PMCID: PMC11376369, DOI: 10.1093/jncics/pkae067.
- Perales O, Jilaveanu L, Adeniran A, Su D, Hurwitz M, Braun D, Kluger H, Schoenfeld D. TIGIT expression in renal cell carcinoma infiltrating T cells is variable and inversely correlated with PD-1 and LAG3. Cancer Immunology, Immunotherapy 2024, 73: 192. PMID: 39105820, PMCID: PMC11303630, DOI: 10.1007/s00262-024-03773-8.
- Atkins M, Jegede O, Haas N, Mcdermott D, Bilen M, Stein M, Sosman J, Alter R, Plimack E, Ornstein M, Hurwitz M, Peace D, Einstein D, Catalano P, Hammers H, Regan M. Treatment-free survival outcomes from the phase II study of nivolumab and salvage nivolumab/ipilimumab in advanced clear cell renal cell carcinoma (HCRN GU16-260-Cohort A). Journal For ImmunoTherapy Of Cancer 2024, 12: e008293. PMID: 38604810, PMCID: PMC11015345, DOI: 10.1136/jitc-2023-008293.
- Pal S, Tran B, Haanen J, Hurwitz M, Sacher A, Tannir N, Budde L, Harrison S, Klobuch S, Patel S, Meza L, Dequeant M, Ma A, He Q, Williams L, Keegan A, Gurary E, Dar H, Karnik S, Guo C, Heath H, Yuen R, Morrow P, Agarwal N, Srour S. CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma. Cancer Discovery 2024, 14: of1-of14. PMID: 38583184, PMCID: PMC11215406, DOI: 10.1158/2159-8290.cd-24-0102.
- Rahman S, Long J, Westvold S, Leapman M, Spees L, Hurwitz M, McManus H, Gross C, Wheeler S, Dinan M. Area Vulnerability and Disparities in Therapy for Patients With Metastatic Renal Cell Carcinoma. JAMA Network Open 2024, 7: e248747. PMID: 38687479, PMCID: PMC11061765, DOI: 10.1001/jamanetworkopen.2024.8747.
- Butt A, Christian J, Kress A, Lu B, Hurwitz M, Goldberg S, Podoltsev N, Gilkes L, Lee A. Providing 0.1 Full-Time Equivalent (FTE) Support to Fellowship Core Faculty Improves Faculty Involvement in Fellowship Education and Recruitment. Journal Of Cancer Education 2024, 39: 325-334. PMID: 38430454, PMCID: PMC12279297, DOI: 10.1007/s13187-024-02414-z.
- Djureinovic D, Weiss S, Krykbaeva I, Qu R, Vathiotis I, Moutafi M, Zhang L, Perdigoto A, Wei W, Anderson G, Damsky W, Hurwitz M, Johnson B, Schoenfeld D, Mahajan A, Hsu F, Miller-Jensen K, Kluger Y, Sznol M, Kaech S, Bosenberg M, Jilaveanu L, Kluger H. A bedside to bench study of anti-PD-1, anti-CD40, and anti-CSF1R indicates that more is not necessarily better. Molecular Cancer 2023, 22: 182. PMID: 37964379, PMCID: PMC10644655, DOI: 10.1186/s12943-023-01884-x.
- Schoenfeld D, Moutafi M, Martinez S, Djureinovic D, Merkin R, Adeniran A, Braun D, Signoretti S, Choueiri T, Parisi F, Hurwitz M, Rimm D, Wei W, Jilaveanu L, Kluger H. Immune dysfunction revealed by digital spatial profiling of immuno-oncology markers in progressive stages of renal cell carcinoma and in brain metastases. Journal For ImmunoTherapy Of Cancer 2023, 11: e007240. PMID: 37586773, PMCID: PMC10432651, DOI: 10.1136/jitc-2023-007240.
- Lokeshwar S, Choksi A, Haltstuch D, Rahman S, Press B, Syed J, Hurwitz M, Kim I, Leapman M. Personalizing approaches to the management of metastatic hormone sensitive prostate cancer: role of advanced imaging, genetics and therapeutics. World Journal Of Urology 2023, 41: 2007-2019. PMID: 37160450, DOI: 10.1007/s00345-023-04409-9.
- Chow R, Long J, Hassan S, Wheeler S, Spees L, Leapman M, Hurwitz M, McManus H, Gross C, Dinan M. Disparities in immune and targeted therapy utilization for older US patients with metastatic renal cell carcinoma. JNCI Cancer Spectrum 2023, 7: pkad036. PMID: 37202354, PMCID: PMC10276895, DOI: 10.1093/jncics/pkad036.
- Atkins M, Jegede O, Haas N, McDermott D, Bilen M, Stein M, Sosman J, Alter R, Plimack E, Ornstein M, Hurwitz M, Peace D, Signoretti S, Denize T, Cimadamore A, Wu C, Braun D, Einstein D, Catalano P, Hammers H. Phase II study of nivolumab and salvage nivolumab/ipilimumab in treatment-naïve patients with advanced non-clear cell renal cell carcinoma (HCRN GU16-260-Cohort B). Journal For ImmunoTherapy Of Cancer 2023, 11: e004780. PMID: 36948504, PMCID: PMC10040058, DOI: 10.1136/jitc-2022-004780.
- Kluger H, Barrett J, Gainor J, Hamid O, Hurwitz M, LaVallee T, Moss R, Zappasodi R, Sullivan R, Tawbi H, Sharon E. Society for Immunotherapy of Cancer (SITC) consensus definitions for resistance to combinations of immune checkpoint inhibitors. Journal For ImmunoTherapy Of Cancer 2023, 11: e005921. PMID: 36918224, PMCID: PMC10016305, DOI: 10.1136/jitc-2022-005921.
- Dizman N, Austin M, Considine B, Jessel S, Schoenfeld D, Merl M, Hurwitz M, Sznol M, Kluger H. Outcomes With Combination Pembrolizumab and Axitinib in Second and Further Line Treatment of Metastatic Renal Cell Carcinoma. Clinical Genitourinary Cancer 2023, 21: 221-229. PMID: 36681606, DOI: 10.1016/j.clgc.2023.01.002.
- Qu R, Kluger Y, Yang J, Zhao J, Hafler D, Krause D, Bersenev A, Bosenberg M, Hurwitz M, Lucca L, Kluger H. Longitudinal single-cell analysis of a patient receiving adoptive cell therapy reveals potential mechanisms of treatment failure. Molecular Cancer 2022, 21: 219. PMID: 36514045, PMCID: PMC9749221, DOI: 10.1186/s12943-022-01688-5.
- Schoenfeld D, Merkin R, Moutafi M, Martinez S, Adeniran A, Kumar D, Jilaveanu L, Hurwitz M, Rimm D, Kluger H. Location matters: LAG3 levels are lower in renal cell carcinoma metastatic sites compared to primary tumors, and expression at metastatic sites only may have prognostic importance. Frontiers In Oncology 2022, 12: 990367. PMID: 36313654, PMCID: PMC9608089, DOI: 10.3389/fonc.2022.990367.
- Haspel R, Genzen J, Wagner J, Lockwood C, Fong K, Adesina A, Browning L, Chabot-Richards D, Cushman-Vokoun A, D’Angelo A, DeFrances M, Devarakonda S, Fernandes H, Fernandez P, Gupta R, Hurwitz M, Lindeman N, Nobori A, Nohr E, Payton J, Saylor B, Sobel M, Stringer K, Vanderbilt C, Young M, Adesina A, Browning L, Chabot-Richards D, Cushman-Vokoun A, D’Angelo A, DeFrances M, Devarakonda S, Fernandes H, Fernandez P, Gupta R, Hurwitz M, Lindeman N, Nobori A, Nohr E, Payton J, Saylor B, Sobel M, Stringer K, Vanderbilt C, Young M. Integration of Genomic Medicine in Pathology Resident Training. American Journal Of Clinical Pathology 2020, 154: 784-791. PMID: 32696061, PMCID: PMC7610262, DOI: 10.1093/ajcp/aqaa094.
- Mohler J, Antonarakis E, Armstrong A, D'Amico A, Davis B, Dorff T, Eastham J, Enke C, Farrington T, Higano C, Horwitz E, Hurwitz M, Ippolito J, Kane C, Kuettel M, Lang J, McKenney J, Netto G, Penson D, Plimack E, Pow-Sang J, Pugh T, Richey S, Roach M, Rosenfeld S, Schaeffer E, Shabsigh A, Small E, Spratt D, Srinivas S, Tward J, Shead D, Freedman-Cass D. Prostate Cancer, Version 2.2019, NCCN Clinical Practice Guidelines in Oncology. Journal Of The National Comprehensive Cancer Network 2019, 17: 479-505. PMID: 31085757, DOI: 10.6004/jnccn.2019.0023.
- Ager C, Reilley M, Nicholas C, Bartkowiak T, Jaiswal A, Curran M, Albershardt T, Bajaj A, Archer J, Reeves R, Ngo L, Berglund P, ter Meulen J, Denis C, Ghadially H, Arnoux T, Chanuc F, Fuseri N, Wilkinson R, Wagtmann N, Morel Y, Andre P, Atkins M, Carlino M, Ribas A, Thompson J, Choueiri T, Hodi F, Hwu W, McDermott D, Atkinson V, Cebon J, Fitzharris B, Jameson M, McNeil C, Hill A, Mangin E, Ahamadi M, van Vugt M, van Zutphen M, Ibrahim N, Long G, Gartrell R, Blake Z, Simoes I, Fu Y, Saito T, Qian Y, Lu Y, Saenger Y, Budhu S, De Henau O, Zappasodi R, Schlunegger K, Freimark B, Hutchins J, Barker C, Wolchok J, Merghoub T, Burova E, Allbritton O, Hong P, Dai J, Pei J, Liu M, Kantrowitz J, Lai V, Poueymirou W, MacDonald D, Ioffe E, Mohrs M, Olson W, Thurston G, Capasso C, Frascaro F, Carpi S, Tähtinen S, Feola S, Fusciello M, Peltonen K, Martins B, Sjöberg M, Pesonen S, Ranki T, Kyruk L, Ylösmäki E, Cerullo V, Cerignoli F, Xi B, Guenther G, Yu N, Muir L, Zhao L, Abassi Y, Cervera-Carrascón V, Siurala M, Santos J, Havunen R, Parviainen S, Hemminki A, Dalgleish A, Mudan S, DeBenedette M, Plachco A, Gamble A, Grogan E, Krisko J, Tcherepanova I, Nicolette C, Dhupkar P, Yu L, Kleinerman E, Gordon N, Grenga I, Lepone L, Gameiro S, Knudson K, Fantini M, Tsang K, Hodge J, Donahue R, Schlom J, Evans E, Bussler H, Mallow C, Reilly C, Torno S, Scrivens M, Foster C, Howell A, Balch L, Knapp A, Leonard J, Paris M, Fisher T, Hu-Lieskovan S, Ribas A, Smith E, Zauderer M, Fogler W, Franklin M, Thayer M, Saims D, Magnani J, Gong J, Gray M, Hutchins J, Freimark B, Fromm G, de Silva S, Giffin L, Xu X, Rose J, Schreiber T, Fantini M, Gameiro S, Knudson K, Clavijo P, Allen C, Donahue R, Lepone L, Grenga I, Hodge J, Tsang K, Schlom J, Gray M, Gong J, Hutchins J, Freimark B, Grogan J, Manieri N, Chiang E, Caplazi P, Yadav M, Hagner P, Chiu H, Waldman M, Klippel A, Thakurta A, Pourdehnad M, Gandhi A, Henrich I, Quick L, Young R, Chou M, Hotson A, Willingham S, Ho P, Choy C, Laport G, McCaffery I, Miller R, Tipton K, Wong K, Singson V, Wong C, Chan C, Huang Y, Liu S, Richardson J, Kavanaugh W, West J, Irving B, Tipton K, Wong K, Singson V, Wong C, Chan C, Huang Y, Liu S, Richardson J, Kavanaugh W, West J, Irving B, Jaini R, Loya M, Eng C, Johnson M, Adjei A, Opyrchal M, Ramalingam S, Janne P, Dominguez G, Gabrilovich D, de Leon L, Hasapidis J, Diede S, Ordentlich P, Cruickshank S, Meyers M, Hellmann M, Kalinski P, Zureikat A, Edwards R, Muthuswamy R, Obermajer N, Urban J, Butterfield L, Gooding W, Zeh H, Bartlett D, Zubkova O, Agapova L, Kapralova M, Krasovskaia L, Ovsepyan A, Lykov M, Eremeev A, Bokovanov V, Grigoryeva O, Karpov A, Ruchko S, Nicolette C, Shuster A, Khalil D, Campesato L, Li Y, Merghoub T, Wolchok J, Lazorchak A, Patterson T, Ding Y, Sasikumar P, Sudarshan N, Gowda N, Ramachandra R, Samiulla D, Giri S, Eswarappa R, Ramachandra M, Tuck D, Wyant T, Leshem J, Liu X, Bera T, Terabe M, Bossenmaier B, Niederfellner G, Reiter Y, Pastan I, Xia L, Xia Y, Hu Y, Wang Y, Bao Y, Dai F, Huang S, Hurt E, Hollingsworth R, Lum L, Chang A, Wicha M, Li Q, Mace T, Makhijani N, Talbert E, Young G, Guttridge D, Conwell D, Lesinski G, Gonzales R, Huffman A, Wang X, Reshef R, MacKinnon A, Chen J, Gross M, Marguier G, Shwonek P, Sotirovska N, Steggerda S, Parlati F, Makkouk A, Bennett M, Chen J, Emberley E, Gross M, Huang T, Li W, MacKinnon A, Marguier G, Neou S, Pan A, Zhang J, Zhang W, Parlati F, Marshall N, Marron T, Agudo J, Brown B, Brody J, McQuinn C, Mace T, Farren M, Komar H, Shakya R, Young G, Ludwug T, Lesinski G, Morillon Y, Hammond S, Schlom J, Greiner J, Nath P, Schwartz A, Maric D, Roberts D, Obermajer N, Bartlett D, Kalinski P, Naing A, Papadopoulos K, Autio K, Wong D, Patel M, Falchook G, Pant S, Ott P, Whiteside M, Patnaik A, Mumm J, Janku F, Chan I, Bauer T, Colen R, VanVlasselaer P, Brown G, Tannir N, Oft M, Infante J, Lipson E, Gopal A, Neelapu S, Armand P, Spurgeon S, Leonard J, Hodi F, Sanborn R, Melero I, Gajewski T, Maurer M, Perna S, Gutierrez A, Clynes R, Mitra P, Suryawanshi S, Gladstone D, Callahan M, Crooks J, Brown S, Gauthier A, de Boisferon M, MacDonald A, Brunet L, Rothwell W, Bell P, Wilson J, Sato-Kaneko F, Yao S, Zhang S, Carson D, Guiducci C, Coffman R, Kitaura K, Matsutani T, Suzuki R, Hayashi T, Cohen E, Schaer D, Li Y, Dobkin J, Amatulli M, Hall G, Doman T, Manro J, Dorsey F, Sams L, Holmgaard R, Persaud K, Ludwig D, Surguladze D, Kauh J, Novosiadly R, Kalos M, Driscoll K, Pandha H, Ralph C, Harrington K, Curti B, Sanborn R, Akerley W, Gupta S, Melcher A, Mansfield D, Kaufman D, Schmidt E, Grose M, Davies B, Karpathy R, Shafren D, Shamalov K, Cohen C, Sharma N, Allison J, Shekarian T, Valsesia-Wittmann S, Caux C, Marabelle A, Slomovitz B, Moore K, Youssoufian H, Posner M, Tewary P, Brooks A, Xu Y, Wijeratne K, Gunatilaka L, Sayers T, Vasilakos J, Alston T, Dovedi S, Elvecrog J, Grigsby I, Herbst R, Johnson K, Moeckly C, Mullins S, Siebenaler K, SternJohn J, Tilahun A, Tomai M, Vogel K, Wilkinson R, Vietsch E, Wellstein A, Wythes M, Crosignani S, Tumang J, Alekar S, Bingham P, Cauwenberghs S, Chaplin J, Dalvie D, Denies S, De Maeseneire C, Feng J, Frederix K, Greasley S, Guo J, Hardwick J, Kaiser S, Jessen K, Kindt E, Letellier M, Li W, Maegley K, Marillier R, Miller N, Murray B, Pirson R, Preillon J, Rabolli V, Ray C, Ryan K, Scales S, Srirangam J, Solowiej J, Stewart A, Streiner N, Torti V, Tsaparikos K, Zheng X, Driessens G, Gomes B, Kraus M, Xu C, Zhang Y, Kradjian G, Qin G, Qi J, Xu X, Marelli B, Yu H, Guzman W, Tighe R, Salazar R, Lo K, English J, Radvanyi L, Lan Y, Zappasodi R, Budhu S, Hellmann M, Postow M, Senbabaoglu Y, Gasmi B, Zhong H, Li Y, Liu C, Hirschhorhn-Cymerman D, Wolchok J, Merghoub T, Zha Y, Malnassy G, Fulton N, Park J, Stock W, Nakamura Y, Gajewski T, Liu H, Ju X, Kosoff R, Ramos K, Coder B, Petit R, Princiotta M, Perry K, Zou J, Arina A, Fernandez C, Zheng W, Beckett M, Mauceri H, Fu Y, Weichselbaum R, DeBenedette M, Lewis W, Gamble A, Nicolette C, Han Y, Wu Y, Yang C, Huang J, Wu D, Li J, Liang X, Zhou X, Hou J, Hassan R, Jahan T, Antonia S, Kindler H, Alley E, Honarmand S, Liu W, Leong M, Whiting C, Nair N, Enstrom A, Lemmens E, Tsujikawa T, Kumar S, Coussens L, Murphy A, Brockstedt D, Koch S, Sebastian M, Weiss C, Früh M, Pless M, Cathomas R, Hilbe W, Pall G, Wehler T, Alt J, Bischoff H, Geissler M, Griesinger F, Kollmeier J, Papachristofilou A, Doener F, Fotin-Mleczek M, Hipp M, Hong H, Kallen K, Klinkhardt U, Stosnach C, Scheel B, Schroeder A, Seibel T, Gnad-Vogt U, Zippelius A, Park H, Ahn Y, Kim T, Kim S, Kim S, Lee Y, Keam B, Kim D, Heo D, Pilon-Thomas S, Weber A, Morse J, Kodumudi K, Liu H, Mullinax J, Sarnaik A, Pike L, Bang A, Ott P, Balboni T, Taylor A, Spektor A, Wilhite T, Krishnan M, Cagney D, Alexander B, Aizer A, Buchbinder E, Awad M, Ghandi L, Hodi F, Schoenfeld J, Schwartz A, Nath P, Lessey-Morillon E, Ridnour L, Roberts D, Segal N, Sharma M, Le D, Ott P, Ferris R, Zelenetz A, Neelapu S, Levy R, Lossos I, Jacobson C, Ramchandren R, Godwin J, Colevas A, Meier R, Krishnan S, Gu X, Neely J, Suryawanshi S, Timmerman J, Vanpouille-Box C, Formenti S, Demaria S, Wennerberg E, Mediero A, Cronstein B, Formenti S, Demaria S, Gustafson M, DiCostanzo A, Wheatley C, Kim C, Bornschlegl S, Gastineau D, Johnson B, Dietz A, MacDonald C, Bucsek M, Qiao G, Hylander B, Repasky E, Turbitt W, Xu Y, Mastro A, Rogers C, Withers S, Wang Z, Khuat L, Dunai C, Blazar B, Longo D, Rebhun R, Grossenbacher S, Monjazeb A, Murphy W, Rowlinson S, Agnello G, Alters S, Lowe D, Scharping N, Menk A, Whetstone R, Zeng X, Delgoffe G, Santos P, Menk A, Shi J, Delgoffe G, Butterfield L, Whetstone R, Menk A, Scharping N, Delgoffe G, Nagasaka M, Sukari A, Byrne-Steele M, Pan W, Hou X, Brown B, Eisenhower M, Han J, Collins N, Manguso R, Pope H, Shrestha Y, Boehm J, Haining W, Cron K, Sivan A, Aquino-Michaels K, Gajewski T, Orecchioni M, Bedognetti D, Hendrickx W, Fuoco C, Spada F, Sgarrella F, Cesareni G, Marincola F, Kostarelos K, Bianco A, Delogu L, Hendrickx W, Roelands J, Boughorbel S, Decock J, Presnell S, Wang E, Marincola F, Kuppen P, Ceccarelli M, Rinchai D, Chaussabel D, Miller L, Bedognetti D, Nguyen A, Sanborn J, Vaske C, Rabizadeh S, Niazi K, Benz S, Patel S, Restifo N, White J, Angiuoli S, Sausen M, Jones S, Sevdali M, Simmons J, Velculescu V, Diaz L, Zhang T, Sims J, Barton S, Gartrell R, Kadenhe-Chiweshe A, Dela Cruz F, Turk A, Lu Y, Mazzeo C, Kung A, Bruce J, Saenger Y, Yamashiro D, Connolly E, Baird J, Crittenden M, Friedman D, Xiao H, Leidner R, Bell B, Young K, Gough M, Bian Z, Kidder K, Liu Y, Curran E, Chen X, Corrales L, Kline J, Dunai C, Aguilar E, Khuat L, Murphy W, Guerriero J, Sotayo A, Ponichtera H, Pourzia A, Schad S, Carrasco R, Lazo S, Bronson R, Letai A, Kornbluth R, Gupta S, Termini J, Guirado E, Stone G, Meyer C, Helming L, Tumang J, Wilson N, Hofmeister R, Radvanyi L, Neubert N, Tillé L, Barras D, Soneson C, Baumgaertner P, Rimoldi D, Gfeller D, Delorenzi M, Fuertes Marraco S, Speiser D, Abraham T, Xiang B, Magee M, Waldman S, Snook A, Blogowski W, Zuba-Surma E, Budkowska M, Salata D, Dolegowska B, Starzynska T, Chan L, Somanchi S, McCulley K, Lee D, Buettner N, Shi F, Myers P, Curbishley S, Penny S, Steadman L, Millar D, Speers E, Ruth N, Wong G, Thimme R, Adams D, Cobbold M, Thomas R, Hendrickx W, Al-Muftah M, Decock J, Wong M, Morse M, McDermott D, Clark J, Kaufman H, Daniels G, Hua H, Rao T, Dutcher J, Kang K, Saunthararajah Y, Velcheti V, Kumar V, Anwar F, Verma A, Chheda Z, Kohanbash G, Sidney J, Okada K, Shrivastav S, Carrera D, Liu S, Jahan N, Mueller S, Pollack I, Carcaboso A, Sette A, Hou Y, Okada H, Field J, Zeng W, Shih V, Law C, Senter P, Gardai S, Okeley N, Penny S, Abelin J, Saeed A, Malaker S, Myers P, Shabanowitz J, Ward S, Hunt D, Cobbold M, Profusek P, Wood L, Shepard D, Grivas P, Kapp K, Volz B, Oswald D, Wittig B, Schmidt M, Sefrin J, Hillringhaus L, Lifke V, Lifke A, Skaletskaya A, Ponte J, Chittenden T, Setiady Y, Valsesia-Wittmann S, Sivado E, Thomas V, El Alaoui M, Papot S, Dumontet C, Dyson M, McCafferty J, El Alaoui S, Verma A, Kumar V, Bommareddy P, Kaufman H, Zloza A, Kohlhapp F, Silk A, Jhawar S, Paneque T, Bommareddy P, Kohlhapp F, Newman J, Beltran P, Zloza A, Kaufman H, Cao F, Hong B, Rodriguez-Cruz T, Song X, Gottschalk S, Calderon H, Illingworth S, Brown A, Fisher K, Seymour L, Champion B, Eriksson E, Wenthe J, Hellström A, Paul-Wetterberg G, Loskog A, Eriksson E, Milenova I, Wenthe J, Ståhle M, Jarblad-Leja J, Ullenhag G, Dimberg A, Moreno R, Alemany R, Loskog A, Eriksson E, Milenova I, Moreno R, Alemany R, Loskog A, Jhawar S, Goyal S, Bommareddy P, Paneque T, Kaufman H, Zloza A, Kaufman H, Silk A, Mehnert J, Gabrail N, Bryan J, Medina D, Bommareddy P, Shafren D, Grose M, Zloza A, Mitchell L, Yagiz K, Lopez F, Mendoza D, Munday A, Gruber H, Jolly D, Fuhrmann S, Radoja S, Tan W, Pourchet A, Frey A, Mohr I, Mulvey M, Ranki T, Pesonen S, Capasso C, Ylösmäki E, Cerullo V, Andtbacka R, Ross M, Agarwala S, Grossmann K, Taylor M, Vetto J, Neves R, Daud A, Khong H, Meek S, Ungerleider R, Welden S, Tanaka M, Williams M, Andtbacka R, Curti B, Hallmeyer S, Fox B, Feng Z, Paustian C, Bifulco C, Grose M, Shafren D, Zafar S, Parviainen S, Siurala M, Hemminki O, Havunen R, Tähtinen S, Bramante S, Vassilev L, Wang H, Lieber A, Hemmi S, de Gruijl T, Kanerva A, Hemminki A, Ansari T, Sundararaman S, Roen D, Lehmann P, Bloom A, Bender L, Walters I, Terabe M, Berzofsky J, Chapelin F, Okada H, Ahrens E, DeFalco J, Harbell M, Manning-Bog A, Scholz A, Zhang D, Baia G, Tan Y, Sokolove J, Kim D, Williamson K, Chen X, Colrain J, Santo G, Nguyen N, Volkmuth W, Greenberg N, Robinson W, Emerling D, Drake C, Petrylak D, Antonarakis E, Kibel A, Chang N, Vu T, Campogan D, Haynes H, Trager J, Sheikh N, Quinn D, Kirk P, Addepalli M, Chang T, Zhang P, Konakova M, Hagihara K, Pai S, VanderVeen L, Obalapur P, Kuo P, Quach P, Fong L, Charych D, Zalevsky J, Langowski J, Addepalli M, Kirksey Y, Nutakki R, Kolarkar S, Pena R, Hoch U, Zalevsky J, Doberstein S, Charych D, Cha J, Mallon Z, Perez M, McDaniel A, Anand S, Uecker D, Nuccitelli R, McDaniel A, Anand S, Cha J, Uecker D, Nuccitelli R, Obermajer N, Urban J, Wieckowski E, Muthuswamy R, Ravindranathan R, Bartlett D, Kalinski P, Renrick A, Thounaojam M, Thomas P, Pellom S, Shanker A, Pellom S, Thounaojam M, Dudimah D, Brooks A, Sayers T, Shanker A, Su Y, Adamus T, Zhang Q, Nechaev S, Kortylewski M, Wei S, Allison J, Anderson C, Tang C, Schoenhals J, Tsouko E, Heymach J, de Groot P, Chang J, Hess K, Diab A, Sharma P, Allison J, Naing A, Hong D, Welsh J, Albershardt T, Parsons A, Leleux J, Reeves R, ter Meulen J, Berglund P, Ascarateil S, Koziol M, Penny S, Malaker S, Steadman L, Myers P, Bai D, Shabanowitz J, Hunt D, Cobbold M, Dai P, Wang W, Yang N, Shuman S, Merghoub T, Wolchok J, Deng L, Dillon P, Petroni G, Brenin D, Bullock K, Olson W, Smolkin M, Smith K, Nail C, Slingluff C, Sharma M, Fa’ak F, Janssen L, Khong H, Xiao Z, Hailemichael Y, Singh M, Vianden C, Diab A, Zalevsky J, Hoch U, Overwijk W, Facciabene A, Stefano P, Chongyung F, Rafail S, Hailemichael Y, Nielsen M, Fa’ak F, Vanderslice P, Woodside D, Market R, Biediger R, Marathi U, Overwijk W, Hollevoet K, Geukens N, Declerck P, Joly N, McIntosh L, Paramithiotis E, Rizell M, Sternby M, Andersson B, Karlsson-Parra A, Kuai R, Ochyl L, Schwendeman A, Moon J, Deng W, Hudson T, Lemmens E, Hanson B, Rae C, Burrill J, Skoble J, Katibah G, Murphy A, deVries M, Brockstedt D, Leong M, Lauer P, Dubensky T, Whiting C, Chen X, Hu Y, Xia Y, Zhou L, Bao Y, Huang S, Ren X, Hurt E, Hollingsworth R, Chang A, Wicha M, Li Q, Aggarwal C, Mangrolia D, Cohen R, Weinstein G, Morrow M, Bauml J, Kraynyak K, Boyer J, Yan J, Lee J, Humeau L, Oyola S, Duff S, Weiner D, Yang Z, Bagarazzi M, McNeel D, Eickhoff J, Jeraj R, Staab M, Straus J, Rekoske B, Liu G, Melssen M, Petroni G, Grosh W, Varhegyi N, Bullock K, Smolkin M, Smith K, Galeassi N, Deacon D, Gaughan E, Slingluff C, Ghisoli M, Barve M, Mennel R, Wallraven G, Manning L, Senzer N, Nemunaitis J, Ogasawara M, Ota S, Peace K, Hale D, Vreeland T, Jackson D, Berry J, Trappey A, Herbert G, Clifton G, Hardin M, Toms A, Qiao N, Litton J, Peoples G, Mittendorf E, Ghamsari L, Flano E, Jacques J, Liu B, Havel J, Makarov V, Merghoub T, Wolchok J, Hellmann M, Chan T, Flechtner J, Stefano P, Facciabene A, Facciponte J, Ugel S, De Sanctis F, Coukos G, Paris S, Pottier A, Levy L, Lu B, Cappuccini F, Pollock E, Bryant R, Hamdy F, Hill A, Redchenko I, Sultan H, Kumai T, Fesenkova V, Celis E, Tsang K, Fantini M, Fernando I, Palena C, David J, Hodge J, Gabitzsch E, Jones F, Gulley J, Schlom J, Herranz M, Rafail S, Ugel S, Facciponte J, Stefano P, Facciabene A, Wada H, Shimizu A, Osada T, Fukaya S, Sasaki E, Abolhalaj M, Askmyr D, Lundberg K, Albrekt A, Greiff L, Lindstedt M, Flies D, Higuchi T, Ornatowski W, Harris J, Adams S, Aguilera T, Rafat M, Castellini L, Shehade H, Kariolis M, Jang D, vonEbyen R, Graves E, Ellies L, Rankin E, Koong A, Giaccia A, Ajina R, Wang S, Smith J, Pierobon M, Jablonski S, Petricoin E, Weiner L, Sherry L, Waller J, Anderson M, Bigley A, Bernatchez C, Haymaker C, Tannir N, Kluger H, Tetzlaff M, Jackson N, Gergel I, Tagliaferri M, Zalevsky J, Hoch U, Hwu P, Snzol M, Hurwitz M, Diab A, Barberi T, Martin A, Suresh R, Barakat D, Harris-Bookman S, Drake C, Friedman A, Berkey S, Downs-Canner S, Delgoffe G, Edwards R, Curiel T, Odunsi K, Bartlett D, Obermajer N, Bruno T, Moore B, Squalls O, Ebner P, Waugh K, Mitchell J, Franklin W, Merrick D, McCarter M, Palmer B, Kern J, Vignali D, Slansky J, Chan A, Qiu X, Fraser K, Jonas A, Ottoson N, Gordon K, Kangas T, Leonardo S, Ertelt K, Walsh R, Uhlik M, Graff J, Bose N, Gupta R, Mandloi N, Paul K, Patil A, Sathian R, Mohan A, Manoharan M, Chaudhuri A, Chen Y, Lin J, Ye Y, Xu C, Chen G, Guo Z, Komarov A, Chenchik A, Makhanov M, Frangou C, Zheng Y, Coltharp C, Unfricht D, Dilworth R, Fridman L, Liu L, Rajopadhye M, Miller P, Concha-Benavente F, Bauman J, Trivedi S, Srivastava R, Ohr J, Heron D, Duvvuri U, Kim S, Gooding W, Ferris R, Torrey H, Mera T, Okubo Y, Vanamee E, Foster R, Faustman D, Gartrell R, Stack E, Lu Y, Izaki D, Beck K, Jia D, Armenta P, White-Stern A, Fu Y, Blake Z, Marks D, Kaufman H, Taback B, Horst B, Saenger Y, Glickman L, Kanne D, Gauthier K, Desbien A, Francica B, Katibah G, Corrales L, Leong J, Sung L, Metchette K, Kasibhatla S, Pferdekamper A, Zheng L, Cho C, Feng Y, McKenna J, Tallarico J, Bender S, Ndubaku C, McWhirter S, Drake C, Gajewski T, Dubensky T, Gugel E, Bell C, Munk A, Muniz L, Bhardwaj N, Zhao F, Evans K, Xiao C, Holtzhausen A, Hanks B, Scholler N, Yin C, Van der Meijs P, Prantner A, Krejsa C, Smith L, Johnson B, Branstetter D, Stein P, Jaen J, Tan J, Chen A, Chen Y, Park T, Powers J, Sexton H, Xu G, Young S, Schindler U, Deng W, Klinke D, Komar H, Mace T, Serpa G, Elnaggar O, Conwell D, Hart P, Schmidt C, Dillhoff M, Jin M, Ostrowski M, Lesinski G, Koti M, Au K, Peterson N, Truesdell P, Reid-Schachter G, Graham C, Craig A, Francis J, Kotlan B, Balatoni T, Farkas E, Toth L, Ujhelyi M, Savolt A, Doleschall Z, Horvath S, Eles K, Olasz J, Csuka O, Kasler M, Liszkay G, Barnea E, Kumar S, Tsujikawa T, Blakely C, Flynn P, Goodman R, Bueno R, Sugarbaker D, Jablons D, Broaddus V, West B, Coussens L, Kunk P, Obeid J, Winters K, Pramoonjago P, Smolkin M, Stelow E, Bauer T, Slingluff C, Rahma O, Lamble A, Kosaka Y, Huang F, Saser K, Adams H, Tognon C, Laderas T, McWeeney S, Loriaux M, Tyner J, Druker B, Lind E, Liu Z, Lu S, Kane L, Ferris R, Liu Z, Shayan G, Lu S, Ferris R, Femel J, Tsujikawa T, Lane R, Booth J, Lund A, Melssen M, Rodriguez A, Slingluff C, Engelhard V, Metelli A, Wu B, Fugle C, Saleh R, Sun S, Wu J, Liu B, Li Z, Morris Z, Guy E, Heinze C, Kler J, Gressett M, Werner L, Gillies S, Korman A, Loibner H, Hank J, Rakhmilevich A, Harari P, Sondel P, Newman J, Zloza A, Huelsmann E, Broucek J, Kaufman H, Brech D, Straub T, Irmler M, Beckers J, Buettner F, Schaeffeler E, Schwab M, Noessner E, Anand S, McDaniel A, Cha J, Uecker D, Nuccitelli R, Ordentlich P, Wolfreys A, Da Costa A, Silva J, Crosby A, Staelens L, Craggs G, Cauvin A, Mason S, Paterson A, Lake A, Armet C, O’Connor R, Hill J, Normant E, Adam A, Biniszkiewicz D, Chappel S, Palombella V, Holland P, Powers J, Becker A, Chen A, Leleti M, Newcomb E, Sexton H, Schindler U, Tan J, Young S, Jaen J, Rapisuwon S, Radfar A, Gardner K, Gibney G, Atkins M, Rennier K, Crowder R, Wang P, Pachynski R, Carrero R, Rivas S, Beceren-Braun F, Anthony S, Schluns K, Sawant D, Chikina M, Yano H, Workman C, Vignali D, Salerno E, Bedognetti D, Mauldin I, Deacon D, Shea S, Pinczewski J, Obeid J, Coukos G, Wang E, Gajewski T, Marincola F, Slingluff C, Spranger S, Horton B, Gajewski T, Suzuki A, Leland P, Joshi B, Puri R, Sweis R, Bao R, Luke J, Gajewski T, Theodoraki M, Mogundo F, Edwards R, Kalinski P, Won H, Moreira D, Gao C, Zhao X, Duttagupta P, Jones J, D’Apuzzo M, Pal S, Kortylewski M. 31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two. Journal For ImmunoTherapy Of Cancer 2016, 4: 73. PMCID: PMC5123381, DOI: 10.1186/s40425-016-0173-6.
- Mohler J, Armstrong A, Bahnson R, D'Amico A, Davis B, Eastham J, Enke C, Farrington T, Higano C, Horwitz E, Hurwitz M, Kane C, Kawachi M, Kuettel M, Lee R, Meeks J, Penson D, Plimack E, Pow-Sang J, Raben D, Richey S, Roach M, Rosenfeld S, Schaeffer E, Skolarus T, Small E, Sonpavde G, Srinivas S, Strope S, Tward J, Shead D, Freedman-Cass D. Prostate Cancer, Version 1.2016. Journal Of The National Comprehensive Cancer Network 2016, 14: 19-30. PMID: 26733552, DOI: 10.6004/jnccn.2016.0004.
- Hurwitz M, Vanderzalm P, Bloom L, Goldman J, Garriga G, Horvitz H. Correction: Abl Kinase Inhibits the Engulfment of Apopotic Cells in Caenorhabditis elegans. PLOS Biology 2009, 7: 10.1371/annotation/2259f958-a68e-4e57-92b5-2ef003070cf1. PMCID: PMC2706740, DOI: 10.1371/annotation/2259f958-a68e-4e57-92b5-2ef003070cf1.
Biography
Michael Hurwitz, MD, PhD, is a medical oncologist who cares for people with genitourinary cancers, including kidney, bladder, prostate, and testicular cancers. He uses immune cell-based therapies to treat a wide range of solid tumors.
“As a clinician, my goal is to provide the best clinical care to my patients,” Dr. Hurwitz says. “To do that, I think it is paramount to address patients’ goals and desires.”
As an associate professor of medicine (medical oncology) at Yale School of Medicine, Dr. Hurwitz focuses on expanding clinical trials for immune cell-based treatments. He collaborates with scientists to develop new approaches for improving outcomes in kidney and other solid tumor cancers. He is also the co-director of the Cell Therapy Clinical Research Program at Yale Cancer Center.
Dr. Hurwitz received his medical degree from Cornell University Medical College and earned a doctoral degree from Rockefeller University. He completed a residency in internal medicine at The NewYork-Presbyterian Hospital/Weill Cornell Medical Center, followed by a fellowship in adult oncology at Dana-Farber Cancer Institute, Brigham and Women’s Hospital, and Massachusetts General Hospital.
Titles
- Associate Professor of Internal Medicine (Medical Oncology)
- Program Director, Hematology/Oncology Fellowship Program
Education & Training
- Postdoctoral FellowMassachusetts Institute of Technology (2010)
- FellowDana-Farber Cancer Institute/Brigham and Women's Hospital/Massachusetts General Hospital (2004)
- Resident in MedicineThe New York Presbyterian Hospital - Weill Cornell Campus (2000)
- MDCornell University Medical College (1998)
- PhDRockefeller University (1997)
- ABHarvard College, Biochemical Sciences (1991)
Additional Information
Honors & Recognitions
- Medical Oncology Teaching Award: Yale Cancer Center (2024)
- Medical Oncology Teaching Award: Yale Medical Oncology and Hematology Fellowship Program (2015), (2023)
Publications
- Coppola G, Kerr S, Cha P, Bersenev A, Olino K, Kluger H, Sznol M, Weiss S, Bosenberg M, Kleinstein S, Krause D, Hurwitz M, Katz S. Ex vivo expansion of melanoma tumor infiltrating lymphocytes leads to a dominant exhausted T cell population with lack of memory markers. Cancer Immunology Research 2026, 14: 861-874. PMID: 41686210, PMCID: PMC13032746, DOI: 10.1158/2326-6066.cir-25-0798.
- Savion-Gaiger N, Considine B, Hasson N, Nelson M, Chiang V, Kluger H, Braun D, Schoenfeld D, Sznol M, Leapman M, Hurwitz M. Survival of patients with metastatic renal cell carcinoma with or without brain metastases. The Oncologist 2025, 30: oyaf387. PMID: 41287461, PMCID: PMC12704413, DOI: 10.1093/oncolo/oyaf387.
- Gaiger N, Hurwitz M, Hafez N, Kluger H, Herold K, Perdigoto A. Immune checkpoint inhibitor-induced diabetes can potentially be effectively treated with infliximab: a case report of two patients. Frontiers In Endocrinology 2025, 16: 1697724. PMID: 41282287, PMCID: PMC12634352, DOI: 10.3389/fendo.2025.1697724.
- Aizenbud L, Gaiger N, Perdigoto A, Mann J, Torres M, Boland G, Lawless A, Silverman S, Schoenfeld D, Destina J, Hasson N, Tran T, Hurwitz M, Austin M, Sullivan R, Herold K, Kluger H. Factors that increase class I MHC expression may contribute to the development of immune checkpoint inhibitor-induced diabetes. Journal For ImmunoTherapy Of Cancer 2025, 13: e012358. PMID: 40935567, PMCID: PMC13059913, DOI: 10.1136/jitc-2025-012358.
- McManus H, Long J, Westvold S, Leapman M, Hurwitz M, Mitchell A, Pollack C, Gross C, Dinan M. Off-Label Use of First-Line Immunotherapy for Metastatic Renal Cell Carcinoma. Clinical Genitourinary Cancer 2025, 23: 102330. PMID: 40186898, PMCID: PMC12084128, DOI: 10.1016/j.clgc.2025.102330.
- Hugaboom M, Wirth L, Street K, Ruthen N, Jegede O, Schindler N, Shah V, Zaemes J, El Ahmar N, Matar S, Savla V, Choueiri T, Denize T, West D, McDermott D, Plimack E, Sosman J, Haas N, Stein M, Alter R, Bilen M, Hurwitz M, Hammers H, Signoretti S, Atkins M, Wu C, Braun D. Presence of Tertiary Lymphoid Structures and Exhausted Tissue-Resident T Cells Determines Clinical Response to PD-1 Blockade in Renal Cell Carcinoma. Cancer Discovery 2025, 15: 948-968. PMID: 39992403, PMCID: PMC12048281, DOI: 10.1158/2159-8290.cd-24-0991.
- Xu W, Birch G, Meliki A, Moritz V, Bharadwaj M, Schindler N, Labaki C, Saliby R, Dinh K, Horst J, Sun M, Kashima S, Hugaboom M, Dighe A, Machaalani M, Lee G, Hurwitz M, McGregor B, Hirsch M, Shukla S, McDermott D, Signoretti S, Romee R, Choueiri T, Braun D. Progressive natural killer cell dysfunction in advanced-stage clear-cell renal cell carcinoma and association with clinical outcomes. ESMO Open 2025, 10: 104105. PMID: 39813824, PMCID: PMC11783098, DOI: 10.1016/j.esmoop.2024.104105.
- Schoenfeld D, Djureinovic D, Su D, Zhang L, Lu B, Kamga L, Mann J, Huck J, Hurwitz M, Braun D, Jilaveanu L, Ring A, Kluger H. Decoy-resistant IL-18 reshapes the tumor microenvironment and enhances rejection by anti-CTLA-4 in renal cell carcinoma. JCI Insight 2024, 10: e184545. PMID: 39561007, PMCID: PMC11721305, DOI: 10.1172/jci.insight.184545.
- Costa P, Arora A, Fernandez Y, Yi I, Bakkila B, Tan H, Coelho P, Campoverde L, Hardy N, Bialick S, Freire A, D’Amato G, Chang Y, Mesenger J, Subhawong T, Haims A, Hurwitz M, Olino K, Turaga K, Deshpande H, Trent J. Sorafenib or anthracycline‐based chemotherapy for progressive desmoid tumors. Cancer 2024, 131: e35647. PMID: 39543805, DOI: 10.1002/cncr.35647.
- Forman R, Long J, Westvold S, Agnish K, McManus H, Leapman M, Hurwitz M, Spees L, Wheeler S, Gross C, Dinan M. Cost trends of metastatic renal cell carcinoma therapy: the impact of oral anticancer agents and immunotherapy. JNCI Cancer Spectrum 2024, 8: pkae067. PMID: 39133171, PMCID: PMC11376369, DOI: 10.1093/jncics/pkae067.
- Perales O, Jilaveanu L, Adeniran A, Su D, Hurwitz M, Braun D, Kluger H, Schoenfeld D. TIGIT expression in renal cell carcinoma infiltrating T cells is variable and inversely correlated with PD-1 and LAG3. Cancer Immunology, Immunotherapy 2024, 73: 192. PMID: 39105820, PMCID: PMC11303630, DOI: 10.1007/s00262-024-03773-8.
- Atkins M, Jegede O, Haas N, Mcdermott D, Bilen M, Stein M, Sosman J, Alter R, Plimack E, Ornstein M, Hurwitz M, Peace D, Einstein D, Catalano P, Hammers H, Regan M. Treatment-free survival outcomes from the phase II study of nivolumab and salvage nivolumab/ipilimumab in advanced clear cell renal cell carcinoma (HCRN GU16-260-Cohort A). Journal For ImmunoTherapy Of Cancer 2024, 12: e008293. PMID: 38604810, PMCID: PMC11015345, DOI: 10.1136/jitc-2023-008293.
- Pal S, Tran B, Haanen J, Hurwitz M, Sacher A, Tannir N, Budde L, Harrison S, Klobuch S, Patel S, Meza L, Dequeant M, Ma A, He Q, Williams L, Keegan A, Gurary E, Dar H, Karnik S, Guo C, Heath H, Yuen R, Morrow P, Agarwal N, Srour S. CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma. Cancer Discovery 2024, 14: of1-of14. PMID: 38583184, PMCID: PMC11215406, DOI: 10.1158/2159-8290.cd-24-0102.
- Rahman S, Long J, Westvold S, Leapman M, Spees L, Hurwitz M, McManus H, Gross C, Wheeler S, Dinan M. Area Vulnerability and Disparities in Therapy for Patients With Metastatic Renal Cell Carcinoma. JAMA Network Open 2024, 7: e248747. PMID: 38687479, PMCID: PMC11061765, DOI: 10.1001/jamanetworkopen.2024.8747.
- Butt A, Christian J, Kress A, Lu B, Hurwitz M, Goldberg S, Podoltsev N, Gilkes L, Lee A. Providing 0.1 Full-Time Equivalent (FTE) Support to Fellowship Core Faculty Improves Faculty Involvement in Fellowship Education and Recruitment. Journal Of Cancer Education 2024, 39: 325-334. PMID: 38430454, PMCID: PMC12279297, DOI: 10.1007/s13187-024-02414-z.
- Djureinovic D, Weiss S, Krykbaeva I, Qu R, Vathiotis I, Moutafi M, Zhang L, Perdigoto A, Wei W, Anderson G, Damsky W, Hurwitz M, Johnson B, Schoenfeld D, Mahajan A, Hsu F, Miller-Jensen K, Kluger Y, Sznol M, Kaech S, Bosenberg M, Jilaveanu L, Kluger H. A bedside to bench study of anti-PD-1, anti-CD40, and anti-CSF1R indicates that more is not necessarily better. Molecular Cancer 2023, 22: 182. PMID: 37964379, PMCID: PMC10644655, DOI: 10.1186/s12943-023-01884-x.
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