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Matthew Vesely, MD, PhD

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Patient type treated
Child, Adult
Accepting new patients
Referral required
Not Applicable
Board Certified in


I am a physician-scientist who has trained in immunology, molecular biology, genetics and clinical dermatology. My overall career goal as a physician-scientist are to integrate fundamental immunology with clinical dermatology. In particular, I am interested in the role of costimulatory and inhibitory immune receptors in cancer immunity, autoimmunity pathogenesis and immunotherapy. My interest in this field was driven by my experience in the Medical Scientist Training Program at Washington University in St. Louis, where I worked in the laboratory of Dr. Robert Schreiber to decipher key molecular regulators of cancer immunoediting. As a consequence, the expertise gained in skin immunology and the emerging immunotherapies to treat melanoma inspired me to become a dermatologist. During my dermatology residency, I joined the laboratory of Dr. Lieping Chen at Yale School of Medicine, who pioneered targeting the PD-1 axis for cancer immunotherapy and has discovered multiple novel immune checkpoint molecules including programmed death receptor-1 homolog (PD-1H) (also known as VISTA). My current research interests include: 1) identification of novel immune checkpoints such as PD-1H/VISTA and others in cutaneous malignancies (e.g., melanoma and keratinocyte carcinomas) and 2) elucidating the inhibitory immune landscape of chronic inflammatory disorders such as psoriasis and cutaneous lupus erythematosus.


  • Assistant Professor of Dermatology

Education & Training

  • Board Certification
    American Board of Dermatology (2017) (2018)
  • Resident
    Yale School of Medicine (Dermatology) (2014-2017) (2017)
  • Intern
    Barnes Jewish Hospital (St. Louis) (2013-2014) (2014)
  • PhD
    Washington University School of Medicine, St. Louis, Immunology (2013)
  • MD
    Washington University School of Medicine, St.Louis (2013)
  • BS
    Creighton University, Biology, Theology, History (2003)

Additional Information

  • Yale Dermatology Branford
    Yale Dermatology - Branford
    322 East Main Street, Ste Suite 2G
    Branford, CT, 06405