- Yale Neurology - GuilfordYale Medicine Multispecialty800 Boston Post RoadGuilford, CT 06437
James A. Giles, MD, PhD
Biography
James A. Giles, MD, PhD, is a vascular neurologist who specializes in the care of patients with cerebrovascular diseases, including ischemic and hemorrhagic strokes.
As an assistant professor at Yale School of Medicine, Dr. Giles's research interests lie in advancing stroke treatment and prevention, with a focus on translating scientific discoveries into clinical practice.
Dr. Giles completed his medical degree and a doctoral degree in neuroscience at The University of Manchester in the United Kingdom. He then completed his neurology residency and stroke fellowship at Washington University School of Medicine and a clinical research fellowship at Oxford University.
Titles
- Assistant Professor of Neurology
Education & Training
- FellowOxford University School of Medicine (2020)
- MPHSWashington University School of Medicine, Population Health Sciences (2020)
- FellowWashington University School of Medicine (2019)
- Chief ResidentWashington University School of Medicine (2018)
- ResidentWashington University School of Medicine (2018)
- MDSchool of Medicine, The University of Manchester, Medicine (2013)
- PhDFaculty of Life Sciences, The University of Manchester, Neuroscience (2012)
Languages Spoken
- English
- Español (Spanish)
Additional Information
- AB of Psychiatry & Neurology, Vascular Neurology (2020)
- AB of Psychiatry & Neurology, Neurology (2018)
- Junior & Early Career Committee, American Neurological Association (2021 - Present): Member
- Kosyakovsky J, Rossitto C, Antonios J, Renedo D, Stapleton C, Sansing L, Navaratnam D, Giles J, Patel A, Matouk C, Sujijantarat N. Clot Composition and Ischemic Stroke Etiology: A Contemporary Narrative Review. Journal Of Clinical Medicine 2025, 14: 6203. PMID: 40943965, PMCID: PMC12429028, DOI: 10.3390/jcm14176203.
- Renedo D, Barak T, DeLong J, Acosta J, Sujijantarat N, Koo A, Rivier C, Clocchiatti-Tuozzo S, Huo S, Antonios J, Giles J, Falcone G, Sheth K, Hebert R, Gunel M, Sansing L, Navaratnam D, Matouk C. Characterizing Stroke Clots Using Single‐Cell Sequencing. Journal Of The American Heart Association 2025, 14: ejaha/2025/041738-t. PMID: 40878981, PMCID: PMC12553457, DOI: 10.1161/jaha.125.041738.
- Mandel D, Shu L, Chang C, Jack N, Guerrero C, Henninger N, Muppa J, Affan M, Lodhi O, Heldner M, Antonenko K, Seiffge D, Arnold M, Omran S, Crandall R, Lester E, Mena D, Arauz A, Nehme A, Boulanger M, Touzé E, Sousa J, Sargento-Freitas J, Barata V, Castro-Chaves P, Brito M, Khan M, Mallick D, Rothstein A, Khazaal O, Kaufman J, Engelter S, Traenka C, de Sousa D, Soares M, Rosa S, Zhou L, Gandhi P, Field T, Mancini S, Metanis I, Leker R, Pan K, Dantu V, Baumgartner K, Burton T, von Rennenberg R, Nolte C, Choi R, MacDonald J, Shahripour R, Guo X, Ghannam M, Almajali M, Samaniego E, Sanchez S, Rioux B, Zine-Eddine F, Poppe A, Fonseca A, Baptista M, Cruz D, Romoli M, De Marco G, Longoni M, Keser Z, Griffin K, Kuohn L, Frontera J, Amar J, Giles J, Zedde M, Pascarella R, Grisendi I, Nzwalo H, Liebeskind D, Molaie A, Cavalier A, Kam W, Mac Grory B, Al Kasab S, Anadani M, Kicielinski K, Eltatawy A, Chervak L, Rivas R, Aziz Y, Bakradze E, Tran T, Gisbert M, Requena M, Velez F, Garcia J, Muddasani V, de Havenon A, Vishnu V, Yaddanapudi S, Adams L, Browngoehl A, Ranasinghe T, Dunston R, Lynch Z, Penckofer M, Siegler J, Mayer S, Willey J, Zubair A, Cheng Y, Sharma R, Marto J, Ferreira V, Klein P, Nguyen T, Asad S, Sarwat Z, Balabhadra A, Patel S, Secchi T, Martins S, Mantovani G, Kim Y, Krishnaiah B, Elangovan C, Lingam S, Qureshi A, Fridman S, Alvarado-Bolanos A, Khasiyev F, Linares G, Mannino M, Terruso V, Vassilopoulou S, Tentolouris-Piperas V, Marino M, Wall V, Indraswari F, Jamal S, Liu S, Alvi M, Ali F, Sarvath M, Morsi R, Kass-Hout T, Shi F, Zhang J, Sokhi D, Said J, Mongare N, Simpkins A, Gomez R, Sen S, Ghani M, Elnazeir M, Xiao H, Kala N, Khan F, Stretz C, Mohammadzadeh N, Goldstein E, Furie K, Yaghi S. Factors Associated With Stroke Recurrence After Initial Diagnosis of Cervical Artery Dissection. Stroke 2025, 56: 1413-1421. PMID: 40143807, DOI: 10.1161/strokeaha.124.048215.
- Sujijantarat N, Templeton K, Antonios J, Renedo D, Koo A, Haynes J, Fathima B, Amllay A, Nowicki K, Huttner A, Giles J, Navaratnam D, Sansing L, Hebert R, King J, Matouk C. Is Clot Composition Associated With Cause of Stroke? A Systematic Review and Meta‐Analysis. Stroke Vascular And Interventional Neurology 2024, 4 DOI: 10.1161/svin.124.001426.
- Bower M, Giles J, Sansing L, Carhuapoma J, Woo D. Stroke Controversies and Debates: Imaging in Intracerebral Hemorrhage. Stroke 2024, 55: 2765-2771. PMID: 39355925, PMCID: PMC11536919, DOI: 10.1161/strokeaha.123.043480.
- Shu L, Akpokiere F, Mandel D, Field T, Leon Guerrero C, Henninger N, Muppa J, Affan M, Haq Lodhi O, Heldner M, Antonenko K, Seiffge D, Arnold M, Salehi Omran S, Crandall R, Lester E, López-Mena D, Arauz A, Nehme A, Boulanger M, Touzé E, Sousa J, Sargento-Freitas J, Barata V, Castro-Chaves P, Brito M, Khan M, Mallick D, Rothstein A, Khazaal O, Kaufmann J, Engelter S, Traenka C, Aguiar de Sousa D, Soares M, Rosa S, Zhou L, Gandhi P, Mancini S, Metanis I, Leker R, Pan K, Dantu V, Baumgartner K, Burton T, Von Rennenberg R, Nolte C, Choi R, MacDonald J, Bavarsad Shahripour R, Guo X, Ghannam M, Almajali M, Samaniego E, Rioux B, Zine-Eddine F, Poppe A, Fonseca A, Baptista M, Cruz D, Romoli M, De Marco G, Longoni M, Keser Z, Griffin K, Kuohn L, Frontera J, Amar J, Giles J, Zedde M, Pascarella R, Grisendi I, Nzwalo H, Liebeskind D, Molaie A, Cavalier A, Kam W, Mac Grory B, Al Kasab S, Anadani M, Kicielinski K, Eltatawy A, Chervak L, Chulluncuy Rivas R, Aziz Y, Mistry E, Bakradze E, Tran T, Rodrigo-Gisbert M, Requena M, Saleh Velez F, Garcia J, Muddasani V, de Havenon A, Sanchez S, Vishnu V, Yaddanapudi S, Adams L, Browngoehl A, Ranasinghe T, Dunston R, Lynch Z, Penckofer M, Siegler J, Mayer S, Willey J, Zubair A, Cheng Y, Sharma R, Marto J, Krupka D, Klein P, Nguyen T, Asad S, Sarwat Z, Balabhadra A, Patel S, Secchi T, Martins S, Mantovani G, Kim Y, Krishnaiah B, Elangovan C, Lingam S, Qureshi A, Fridman S, Alvarado A, Khasiyev F, Linares G, Mannino M, Terruso V, Tountopoulou A, Tentolouris-Piperas V, Martinez-Marino M, Carrasco Wall V, Indraswari F, El Jamal S, Liu S, Zhou M, Alvi M, Ali F, Sarvath M, Morsi R, Kass-Hout T, Shi F, Zhang J, Sokhi D, Said J, Mongare N, Simpkins A, Gomez R, Sen S, Ghani M, Elnazeir M, Wangqin R, Xiao H, Kala N, Khan F, Stretz C, Mohammadzadeh N, Goldstein E, Furie K, Yaghi S. Intravenous Thrombolysis in Patients With Cervical Artery Dissection. Neurology 2024, 103: e209843. PMID: 39298709, PMCID: PMC11415265, DOI: 10.1212/wnl.0000000000209843.
- Giles J, Lee J, Dhar R. Multi-Omics Approaches to Discovering Acute Stroke Injury and Recovery Mechanisms. 2024, 547-584. DOI: 10.1007/978-3-031-41777-1_19.
- Bakradze E, Shu L, Henninger N, Prabhakaran S, Siegler J, De Marchis G, Giles J, Dittrich T, Heldner M, Antonenko K, Kam W, Liebeskind D, Simpkins A, Nguyen T, Yaghi S, Liberman A. Delayed Diagnosis in Cerebral Venous Thrombosis: Associated Factors and Clinical Outcomes. Journal Of The American Heart Association 2023, 12: e030421. PMID: 37753785, PMCID: PMC10727263, DOI: 10.1161/jaha.123.030421.
- Shu L, Bakradze E, Omran SS, Giles J, Amar J, Henninger N, Elnazeir M, Liberman A, Moncrieffe K, Rotblat J, Sharma R, Cheng Y, Zubair AS, Simpkins A, Li G, Kung J, Perez D, Heldner MR, Scutelnic A, von Martial R, Siepen B, Rothstein A, Khazaal O, Do D, Al Kasab S, Rahman LA, Mistry EA, Kerrigan D, Lafever H, Nguyen TN, Klein P, Aparicio HJ, Frontera JA, Kuohn L, Agarwal S, Stretz C, Kala N, ElJamal S, Chang A, Cutting S, Indraswari F, de Havenon A, Muddasani V, Wu T, Wilson D, Nouh A, Asad D, Qureshi A, Moore J, Khatri P, Aziz Y, Casteigne B, Khan M, Cheng Y, Grory BM, Weiss M, Ryan D, Vedovati MC, Paciaroni M, Siegler J, Kamen S, Yu S, Guerrero CL, Atallah E, De Marchis GM, Brehm A, Dittrich T, Psychogios M, Alvarado-Dyer R, Kass-Hout T, Prabhakaran S, Honda T, Liebeskind D, Furie K, Yaghi S. Predictors of Recurrent Venous Thrombosis After Cerebral Venous Thrombosis. Neurology 2022, 99: e2368-e2377. PMID: 36123126, PMCID: PMC9687409, DOI: 10.1212/wnl.0000000000201122.
- Yaghi S, Shu L, Bakradze E, Salehi Omran S, Giles JA, Amar JY, Henninger N, Elnazeir M, Liberman AL, Moncrieffe K, Lu J, Sharma R, Cheng Y, Zubair AS, Simpkins AN, Li GT, Kung JC, Perez D, Heldner M, Scutelnic A, Seiffge D, Siepen B, Rothstein A, Khazaal O, Do D, Kasab S, Rahman LA, Mistry EA, Kerrigan D, Lafever H, Nguyen TN, Klein P, Aparicio H, Frontera J, Kuohn L, Agarwal S, Stretz C, Kala N, El Jamal S, Chang A, Cutting S, Xiao H, de Havenon A, Muddasani V, Wu T, Wilson D, Nouh A, Asad SD, Qureshi A, Moore J, Khatri P, Aziz Y, Casteigne B, Khan M, Cheng Y, Mac Grory B, Weiss M, Ryan D, Vedovati MC, Paciaroni M, Siegler JE, Kamen S, Yu S, Leon Guerrero C, Atallah E, De Marchis GM, Brehm A, Dittrich T, Psychogios M, Alvarado-Dyer R, Kass-Hout T, Prabhakaran S, Honda T, Liebeskind DS, Furie K. Direct Oral Anticoagulants Versus Warfarin in the Treatment of Cerebral Venous Thrombosis (ACTION-CVT): A Multicenter International Study. Stroke 2022, 53: 728-738. PMID: 35143325, DOI: 10.1161/strokeaha.121.037541.
- Giles J, Vellimana A, Adeoye O. Endovascular Treatment of Acute Stroke. Current Neurology And Neuroscience Reports 2022, 22: 83-91. PMID: 35098425, DOI: 10.1007/s11910-022-01168-9.
- Petersen NH, Kodali S, Meng C, Li F, Nguyen CK, Peshwe KU, Strander S, Silverman A, Kimmel A, Wang A, Anadani M, Almallouhi E, Spiotta AM, Kim JT, Giles JA, Keyrouz SG, Farooqui M, Zevallos C, Maier IL, Psychogios MN, Liman J, Riou-Comte N, Richard S, Gory B, Wolfe S, Brown PA, Fargen KM, Mistry EA, Fakhri H, Mistry AM, Wong KH, de Havenon A, Nascimento FA, Kan P, Matouk C, Ortega-Gutiérrez S, Sheth KN. Blood Pressure Trajectory Groups and Outcome After Endovascular Thrombectomy: A Multicenter Study. Stroke 2021, 53: 1216-1225. PMID: 34781705, PMCID: PMC8960326, DOI: 10.1161/strokeaha.121.034408.
- Akbik F, Alawieh A, Cawley CM, Howard BM, Tong FC, Nahab F, Saad H, Dimisko L, Mustroph C, Samuels OB, Pradilla G, Maier I, Goyal N, Starke RM, Rai A, Fargen KM, Psychogios MN, Jabbour P, De Leacy R, Giles J, Dumont TM, Kan P, Arthur AS, Crosa RJ, Gory B, Spiotta AM, Grossberg JA. Differential effect of mechanical thrombectomy and intravenous thrombolysis in atrial fibrillation associated stroke. Journal Of Neurointerventional Surgery 2021, 13: 883-888. PMID: 33318066, PMCID: PMC8377613, DOI: 10.1136/neurintsurg-2020-016720.
- Yaghi S, Mistry E, de Havenon A, Guerrero C, Nouh A, Liberman AL, Giles J, Liu A, Nagy M, Kaushal A, Azher I, Mac Grory B, Fakhri H, Espaillat K, Asad SD, Pasupuleti H, Martin H, Tan J, Veerasamy M, Esenwa C, Cheng N, Moncrieffe K, Moeini‐Naghani I, Siddu M, Scher E, Trivedi T, Wu T, Khan M, Keyrouz S, Furie K, Henninger N. Effect of Alteplase Use on Outcomes in Patients With Atrial Fibrillation: Analysis of the Initiation of Anticoagulation After Cardioembolic Stroke Study. Journal Of The American Heart Association 2021, 10: e020945. PMID: 34323120, PMCID: PMC8475683, DOI: 10.1161/jaha.121.020945.
- Holder D, Leeseberg K, Giles J, Lee J, Namazie S, Ford A. Central Triage of Acute Stroke Patients Across a Distributive Stroke Network Is Safe and Reduces Transfer Denials. Stroke 2021, 52: 2671-2675. PMID: 34154389, PMCID: PMC8316396, DOI: 10.1161/strokeaha.120.033018.
- Giles J, Balasetti V, Zazulia A. Non-Vitamin K Antagonist Oral Anticoagulants for the Treatment of Cerebral Venous Sinus Thrombosis: a Retrospective, Matched Cohort Analysis. Neurocritical Care 2021, 35: 783-788. PMID: 34046861, DOI: 10.1007/s12028-021-01244-x.
- Yaghi S, Henninger N, Giles JA, Guerrero C, Mistry E, Liberman AL, Asad D, Liu A, Nagy M, Kaushal A, Azher I, Mac Grory B, Fakhri H, Espaillat K, Pasupuleti H, Martin H, Tan J, Veerasamy M, Esenwa C, Cheng N, Moncrieffe K, Moeini-Naghani I, Siddu M, Scher E, Trivedi T, Furie KL, Keyrouz SG, Nouh A, de Havenon A, Khan M, Smith EE, Gurol ME. Ischaemic stroke on anticoagulation therapy and early recurrence in acute cardioembolic stroke: the IAC study. Journal Of Neurology Neurosurgery & Psychiatry 2021, 92: 1062-1067. PMID: 33903185, PMCID: PMC8448925, DOI: 10.1136/jnnp-2021-326166.
- Alawieh AM, Eid M, Anadani M, Sattur M, Maier IL, Feng W, Goyal N, Starke RM, Rai A, Fargen KM, Psychogios MN, De Leacy R, Grossberg JA, Keyrouz SG, Dumont TM, Kan P, Lena J, Liman J, Arthur AS, Elijovich L, Mccarthy DJ, Saini V, Wolfe SQ, Mocco J, Fifi JT, Nascimento FA, Giles JA, Allen M, Crosa R, Fox WC, Gory B, Spiotta AM. Thrombectomy Technique Predicts Outcome in Posterior Circulation Stroke-Insights from the STAR Collaboration. Neurosurgery 2020, 87: 982-991. PMID: 32433730, DOI: 10.1093/neuros/nyaa179.
- Hill E, El-Haj M, Giles J, Fox I. Using electrodiagnostics to define injury patterns amenable to nerve transfer surgery in tetraplegia: an illustrative case report. Spinal Cord Series And Cases 2020, 6: 78. PMID: 32826861, PMCID: PMC7442626, DOI: 10.1038/s41394-020-00325-x.
- Yaghi S, Mistry E, Liberman AL, Giles J, Asad SD, Liu A, Nagy M, Kaushal A, Azher I, Mac Grory B, Fakhri H, Brown Espaillat K, Pasupuleti H, Martin H, Tan J, Veerasamy M, Esenwa C, Cheng N, Moncrieffe K, Moeini-Naghani I, Siddu M, Scher E, Trivedi T, Lord A, Furie K, Keyrouz S, Nouh A, Leon Guerrero CR, de Havenon A, Khan M, Henninger N. Anticoagulation Type and Early Recurrence in Cardioembolic Stroke. Stroke 2020, 51: 2724-2732. PMID: 32757753, PMCID: PMC7484360, DOI: 10.1161/strokeaha.120.028867.
- Yaghi S, Trivedi T, Henninger N, Giles J, Liu A, Nagy M, Kaushal A, Azher I, Mac Grory B, Fakhri H, Espaillat K, Asad S, Pasupuleti H, Martin H, Tan J, Veerasamy M, Liberman A, Esenwa C, Cheng N, Moncrieffe K, Moeini‐Naghani I, Siddu M, Scher E, Guerrero C, Khan M, Nouh A, Mistry E, Keyrouz S, Furie K. Anticoagulation Timing in Cardioembolic Stroke and Recurrent Event Risk. Annals Of Neurology 2020, 88: 807-816. PMID: 32656768, PMCID: PMC8259451, DOI: 10.1002/ana.25844.
- Yaghi S, Liberman AL, Henninger N, Grory BM, Nouh A, Scher E, Giles J, Liu A, Nagy M, Kaushal A, Azher I, Fakhri H, Espaillat KB, Asad SD, Pasupuleti H, Martin H, Tan J, Veerasamy M, Esenwa C, Cheng N, Moncrieffe K, Moeini-Naghani I, Siddu M, Trivedi T, Ishida K, Frontera J, Lord A, Furie K, Keyrouz S, de Havenon A, Mistry E, Leon Guerrero CR, Khan M. Factors associated with therapeutic anticoagulation status in patients with ischemic stroke and atrial fibrillation. Journal Of Stroke And Cerebrovascular Diseases 2020, 29: 104888. PMID: 32414583, PMCID: PMC8207529, DOI: 10.1016/j.jstrokecerebrovasdis.2020.104888.
- Yaghi S, Henninger N, Scher E, Giles J, Liu A, Nagy M, Kaushal A, Azher I, Mac Grory B, Fakhri H, Espaillat K, Asad S, Pasupuleti H, Martin H, Tan J, Veerasamy M, Liberman A, Esenwa C, Cheng N, Moncrieffe K, Moeini-Naghani I, Siddu M, Trivedi T, Guerrero C, Khan M, Nouh A, Mistry E, Keyrouz S, Furie K. Early ischaemic and haemorrhagic complications after atrial fibrillation-related ischaemic stroke: analysis of the IAC study. Journal Of Neurology Neurosurgery & Psychiatry 2020, 91: 750-755. PMID: 32404380, PMCID: PMC8179007, DOI: 10.1136/jnnp-2020-323041.
- Anadani M, Arthur A, Tsivgoulis G, Simpson K, Alawieh A, Orabi Y, Goyal N, Alexandrov A, Maier I, Psychogios M, Liman J, Brinton D, Swisher C, Shah S, Inamullah O, Keyrouz S, Kansagra A, Allen M, Giles J, Wolfe S, Fargen K, Gory B, De Marini P, Kan P, Nascimento F, Almallouhi E, Petersen N, Kodali S, Rahman S, Richard S, Spiotta A. Blood Pressure Goals and Clinical Outcomes after Successful Endovascular Therapy: A Multicenter Study. Annals Of Neurology 2020, 87: 830-839. PMID: 32187711, DOI: 10.1002/ana.25716.
- Anadani M, Arthur AS, Alawieh A, Orabi Y, Alexandrov A, Goyal N, Psychogios MN, Maier I, Kim JT, Keyrouz SG, de Havenon A, Petersen NH, Pandhi A, Swisher CB, Inamullah O, Liman J, Kodali S, Giles JA, Allen M, Wolfe SQ, Tsivgoulis G, Cagle BA, Oravec CS, Gory B, De Marini P, Kan P, Rahman S, Richard S, Nascimento FA, Spiotta A. Blood pressure reduction and outcome after endovascular therapy with successful reperfusion: a multicenter study. Journal Of NeuroInterventional Surgery 2019, 12: 932-936. PMID: 31806668, PMCID: PMC7998040, DOI: 10.1136/neurintsurg-2019-015561.
- Anadani M, Orabi M, Alawieh A, Goyal N, Alexandrov A, Petersen N, Kodali S, Maier I, Psychogios M, Swisher C, Inamullah O, Kansagra A, Giles J, Wolfe S, Singh J, Gory B, De Marini P, Kan P, Nascimento F, Freire L, Pandhi A, Mitchell H, Kim J, Fargen K, Al Kasab S, Liman J, Rahman S, Allen M, Richard S, Spiotta A. Blood Pressure and Outcome After Mechanical Thrombectomy With Successful Revascularization. Stroke 2019, 50: 2448-2454. PMID: 31318633, DOI: 10.1161/strokeaha.118.024687.
- Tamachi S, Giles J, Dornan T, Hill E. “You understand that whole big situation they’re in”: interpretative phenomenological analysis of peer-assisted learning. BMC Medical Education 2018, 18: 197. PMID: 30107801, PMCID: PMC6092812, DOI: 10.1186/s12909-018-1291-2.
- Giles J, Greenhalgh A, Denes A, Nieswandt B, Coutts G, McColl B, Allan S. Neutrophil infiltration to the brain is platelet‐dependent, and is reversed by blockade of platelet GPIbα. Immunology 2018, 154: 322-328. PMID: 29325217, PMCID: PMC5979746, DOI: 10.1111/imm.12892.
- Giles J, Hill E. Examining our hidden curricula: powerful, visible, gendered and discriminatory. Medical Education 2015, 49: 244-246. PMID: 25693983, DOI: 10.1111/medu.12664.
- Giles J, Greenhalgh A, Davies C, Denes A, Shaw T, Coutts G, Rothwell N, McColl B, Allan S. Requirement for interleukin‐1 to drive brain inflammation reveals tissue‐specific mechanisms of innate immunity. European Journal Of Immunology 2014, 45: 525-530. PMID: 25367678, PMCID: PMC4357393, DOI: 10.1002/eji.201444748.
- Giles J, Hill E. Looking more reflexively at surgical culture. Medical Education 2014, 48: 1245-1245. PMID: 25413918, DOI: 10.1111/medu.12611.
- Hill E, Giles J. Career decisions and gender: the illusion of choice? Perspectives On Medical Education 2014, 3: 151-154. PMID: 24957796, PMCID: PMC4078050, DOI: 10.1007/s40037-014-0128-x.
- Girard S, Brough D, Lopez-Castejon G, Giles J, Rothwell N, Allan S. Microglia and macrophages differentially modulate cell death after brain injury caused by oxygen‐glucose deprivation in organotypic brain slices. Glia 2013, 61: 813-824. PMID: 23404620, PMCID: PMC3644876, DOI: 10.1002/glia.22478.
- Hill E, Giles J, Dornan T. Teaching in a busy clinic. Practical Neurology 2012, 12: 376. PMID: 23144301, DOI: 10.1136/practneurol-2012-000267.
- Luheshi N, Giles J, Lopez‐Castejon G, Brough D. Sphingosine regulates the NLRP3‐inflammasome and IL‐1β release from macrophages. European Journal Of Immunology 2011, 42: 716-725. PMID: 22105559, PMCID: PMC3491674, DOI: 10.1002/eji.201142079.
- Giles J, Greenhalgh A, Denes A, Thornton P, Rothwell N, McColl B, Allan S. 48 Endovascular inflammation may occur via tissue-specific mechanisms. Heart 2011, 97: e7. DOI: 10.1136/heartjnl-2011-300920b.48.
- Hill E, Liuzzi F, Giles J. Peer‐assisted learning from three perspectives: student, tutor and co‐ordinator. The Clinical Teacher 2010, 7: 244-246. PMID: 21134199, DOI: 10.1111/j.1743-498x.2010.00399.x.
- Giles J. Clinical neuroscience attachments: a student’s view of ‘neurophobia’. The Clinical Teacher 2010, 7: 9-13. PMID: 21134136, DOI: 10.1111/j.1743-498x.2009.00330.x.
- Giles J. Surgical training and the European Working Time Directive: The role of informal workplace learning. International Journal Of Surgery 2010, 8: 179-180. PMID: 20144752, DOI: 10.1016/j.ijsu.2010.01.011.
- Yale Neurology - GuilfordYale Medicine Multispecialty800 Boston Post RoadGuilford, CT 06437
Biography
James A. Giles, MD, PhD, is a vascular neurologist who specializes in the care of patients with cerebrovascular diseases, including ischemic and hemorrhagic strokes.
As an assistant professor at Yale School of Medicine, Dr. Giles's research interests lie in advancing stroke treatment and prevention, with a focus on translating scientific discoveries into clinical practice.
Dr. Giles completed his medical degree and a doctoral degree in neuroscience at The University of Manchester in the United Kingdom. He then completed his neurology residency and stroke fellowship at Washington University School of Medicine and a clinical research fellowship at Oxford University.
Titles
- Assistant Professor of Neurology
Education & Training
- FellowOxford University School of Medicine (2020)
- MPHSWashington University School of Medicine, Population Health Sciences (2020)
- FellowWashington University School of Medicine (2019)
- Chief ResidentWashington University School of Medicine (2018)
- ResidentWashington University School of Medicine (2018)
- MDSchool of Medicine, The University of Manchester, Medicine (2013)
- PhDFaculty of Life Sciences, The University of Manchester, Neuroscience (2012)
Languages Spoken
- English
- Español (Spanish)
Additional Information
- AB of Psychiatry & Neurology, Vascular Neurology (2020)
- AB of Psychiatry & Neurology, Neurology (2018)
- Junior & Early Career Committee, American Neurological Association (2021 - Present): Member
- Kosyakovsky J, Rossitto C, Antonios J, Renedo D, Stapleton C, Sansing L, Navaratnam D, Giles J, Patel A, Matouk C, Sujijantarat N. Clot Composition and Ischemic Stroke Etiology: A Contemporary Narrative Review. Journal Of Clinical Medicine 2025, 14: 6203. PMID: 40943965, PMCID: PMC12429028, DOI: 10.3390/jcm14176203.
- Renedo D, Barak T, DeLong J, Acosta J, Sujijantarat N, Koo A, Rivier C, Clocchiatti-Tuozzo S, Huo S, Antonios J, Giles J, Falcone G, Sheth K, Hebert R, Gunel M, Sansing L, Navaratnam D, Matouk C. Characterizing Stroke Clots Using Single‐Cell Sequencing. Journal Of The American Heart Association 2025, 14: ejaha/2025/041738-t. PMID: 40878981, PMCID: PMC12553457, DOI: 10.1161/jaha.125.041738.
- Mandel D, Shu L, Chang C, Jack N, Guerrero C, Henninger N, Muppa J, Affan M, Lodhi O, Heldner M, Antonenko K, Seiffge D, Arnold M, Omran S, Crandall R, Lester E, Mena D, Arauz A, Nehme A, Boulanger M, Touzé E, Sousa J, Sargento-Freitas J, Barata V, Castro-Chaves P, Brito M, Khan M, Mallick D, Rothstein A, Khazaal O, Kaufman J, Engelter S, Traenka C, de Sousa D, Soares M, Rosa S, Zhou L, Gandhi P, Field T, Mancini S, Metanis I, Leker R, Pan K, Dantu V, Baumgartner K, Burton T, von Rennenberg R, Nolte C, Choi R, MacDonald J, Shahripour R, Guo X, Ghannam M, Almajali M, Samaniego E, Sanchez S, Rioux B, Zine-Eddine F, Poppe A, Fonseca A, Baptista M, Cruz D, Romoli M, De Marco G, Longoni M, Keser Z, Griffin K, Kuohn L, Frontera J, Amar J, Giles J, Zedde M, Pascarella R, Grisendi I, Nzwalo H, Liebeskind D, Molaie A, Cavalier A, Kam W, Mac Grory B, Al Kasab S, Anadani M, Kicielinski K, Eltatawy A, Chervak L, Rivas R, Aziz Y, Bakradze E, Tran T, Gisbert M, Requena M, Velez F, Garcia J, Muddasani V, de Havenon A, Vishnu V, Yaddanapudi S, Adams L, Browngoehl A, Ranasinghe T, Dunston R, Lynch Z, Penckofer M, Siegler J, Mayer S, Willey J, Zubair A, Cheng Y, Sharma R, Marto J, Ferreira V, Klein P, Nguyen T, Asad S, Sarwat Z, Balabhadra A, Patel S, Secchi T, Martins S, Mantovani G, Kim Y, Krishnaiah B, Elangovan C, Lingam S, Qureshi A, Fridman S, Alvarado-Bolanos A, Khasiyev F, Linares G, Mannino M, Terruso V, Vassilopoulou S, Tentolouris-Piperas V, Marino M, Wall V, Indraswari F, Jamal S, Liu S, Alvi M, Ali F, Sarvath M, Morsi R, Kass-Hout T, Shi F, Zhang J, Sokhi D, Said J, Mongare N, Simpkins A, Gomez R, Sen S, Ghani M, Elnazeir M, Xiao H, Kala N, Khan F, Stretz C, Mohammadzadeh N, Goldstein E, Furie K, Yaghi S. Factors Associated With Stroke Recurrence After Initial Diagnosis of Cervical Artery Dissection. Stroke 2025, 56: 1413-1421. PMID: 40143807, DOI: 10.1161/strokeaha.124.048215.
- Sujijantarat N, Templeton K, Antonios J, Renedo D, Koo A, Haynes J, Fathima B, Amllay A, Nowicki K, Huttner A, Giles J, Navaratnam D, Sansing L, Hebert R, King J, Matouk C. Is Clot Composition Associated With Cause of Stroke? A Systematic Review and Meta‐Analysis. Stroke Vascular And Interventional Neurology 2024, 4 DOI: 10.1161/svin.124.001426.
- Bower M, Giles J, Sansing L, Carhuapoma J, Woo D. Stroke Controversies and Debates: Imaging in Intracerebral Hemorrhage. Stroke 2024, 55: 2765-2771. PMID: 39355925, PMCID: PMC11536919, DOI: 10.1161/strokeaha.123.043480.
- Shu L, Akpokiere F, Mandel D, Field T, Leon Guerrero C, Henninger N, Muppa J, Affan M, Haq Lodhi O, Heldner M, Antonenko K, Seiffge D, Arnold M, Salehi Omran S, Crandall R, Lester E, López-Mena D, Arauz A, Nehme A, Boulanger M, Touzé E, Sousa J, Sargento-Freitas J, Barata V, Castro-Chaves P, Brito M, Khan M, Mallick D, Rothstein A, Khazaal O, Kaufmann J, Engelter S, Traenka C, Aguiar de Sousa D, Soares M, Rosa S, Zhou L, Gandhi P, Mancini S, Metanis I, Leker R, Pan K, Dantu V, Baumgartner K, Burton T, Von Rennenberg R, Nolte C, Choi R, MacDonald J, Bavarsad Shahripour R, Guo X, Ghannam M, Almajali M, Samaniego E, Rioux B, Zine-Eddine F, Poppe A, Fonseca A, Baptista M, Cruz D, Romoli M, De Marco G, Longoni M, Keser Z, Griffin K, Kuohn L, Frontera J, Amar J, Giles J, Zedde M, Pascarella R, Grisendi I, Nzwalo H, Liebeskind D, Molaie A, Cavalier A, Kam W, Mac Grory B, Al Kasab S, Anadani M, Kicielinski K, Eltatawy A, Chervak L, Chulluncuy Rivas R, Aziz Y, Mistry E, Bakradze E, Tran T, Rodrigo-Gisbert M, Requena M, Saleh Velez F, Garcia J, Muddasani V, de Havenon A, Sanchez S, Vishnu V, Yaddanapudi S, Adams L, Browngoehl A, Ranasinghe T, Dunston R, Lynch Z, Penckofer M, Siegler J, Mayer S, Willey J, Zubair A, Cheng Y, Sharma R, Marto J, Krupka D, Klein P, Nguyen T, Asad S, Sarwat Z, Balabhadra A, Patel S, Secchi T, Martins S, Mantovani G, Kim Y, Krishnaiah B, Elangovan C, Lingam S, Qureshi A, Fridman S, Alvarado A, Khasiyev F, Linares G, Mannino M, Terruso V, Tountopoulou A, Tentolouris-Piperas V, Martinez-Marino M, Carrasco Wall V, Indraswari F, El Jamal S, Liu S, Zhou M, Alvi M, Ali F, Sarvath M, Morsi R, Kass-Hout T, Shi F, Zhang J, Sokhi D, Said J, Mongare N, Simpkins A, Gomez R, Sen S, Ghani M, Elnazeir M, Wangqin R, Xiao H, Kala N, Khan F, Stretz C, Mohammadzadeh N, Goldstein E, Furie K, Yaghi S. Intravenous Thrombolysis in Patients With Cervical Artery Dissection. Neurology 2024, 103: e209843. PMID: 39298709, PMCID: PMC11415265, DOI: 10.1212/wnl.0000000000209843.
- Giles J, Lee J, Dhar R. Multi-Omics Approaches to Discovering Acute Stroke Injury and Recovery Mechanisms. 2024, 547-584. DOI: 10.1007/978-3-031-41777-1_19.
- Bakradze E, Shu L, Henninger N, Prabhakaran S, Siegler J, De Marchis G, Giles J, Dittrich T, Heldner M, Antonenko K, Kam W, Liebeskind D, Simpkins A, Nguyen T, Yaghi S, Liberman A. Delayed Diagnosis in Cerebral Venous Thrombosis: Associated Factors and Clinical Outcomes. Journal Of The American Heart Association 2023, 12: e030421. PMID: 37753785, PMCID: PMC10727263, DOI: 10.1161/jaha.123.030421.
- Shu L, Bakradze E, Omran SS, Giles J, Amar J, Henninger N, Elnazeir M, Liberman A, Moncrieffe K, Rotblat J, Sharma R, Cheng Y, Zubair AS, Simpkins A, Li G, Kung J, Perez D, Heldner MR, Scutelnic A, von Martial R, Siepen B, Rothstein A, Khazaal O, Do D, Al Kasab S, Rahman LA, Mistry EA, Kerrigan D, Lafever H, Nguyen TN, Klein P, Aparicio HJ, Frontera JA, Kuohn L, Agarwal S, Stretz C, Kala N, ElJamal S, Chang A, Cutting S, Indraswari F, de Havenon A, Muddasani V, Wu T, Wilson D, Nouh A, Asad D, Qureshi A, Moore J, Khatri P, Aziz Y, Casteigne B, Khan M, Cheng Y, Grory BM, Weiss M, Ryan D, Vedovati MC, Paciaroni M, Siegler J, Kamen S, Yu S, Guerrero CL, Atallah E, De Marchis GM, Brehm A, Dittrich T, Psychogios M, Alvarado-Dyer R, Kass-Hout T, Prabhakaran S, Honda T, Liebeskind D, Furie K, Yaghi S. Predictors of Recurrent Venous Thrombosis After Cerebral Venous Thrombosis. Neurology 2022, 99: e2368-e2377. PMID: 36123126, PMCID: PMC9687409, DOI: 10.1212/wnl.0000000000201122.
- Yaghi S, Shu L, Bakradze E, Salehi Omran S, Giles JA, Amar JY, Henninger N, Elnazeir M, Liberman AL, Moncrieffe K, Lu J, Sharma R, Cheng Y, Zubair AS, Simpkins AN, Li GT, Kung JC, Perez D, Heldner M, Scutelnic A, Seiffge D, Siepen B, Rothstein A, Khazaal O, Do D, Kasab S, Rahman LA, Mistry EA, Kerrigan D, Lafever H, Nguyen TN, Klein P, Aparicio H, Frontera J, Kuohn L, Agarwal S, Stretz C, Kala N, El Jamal S, Chang A, Cutting S, Xiao H, de Havenon A, Muddasani V, Wu T, Wilson D, Nouh A, Asad SD, Qureshi A, Moore J, Khatri P, Aziz Y, Casteigne B, Khan M, Cheng Y, Mac Grory B, Weiss M, Ryan D, Vedovati MC, Paciaroni M, Siegler JE, Kamen S, Yu S, Leon Guerrero C, Atallah E, De Marchis GM, Brehm A, Dittrich T, Psychogios M, Alvarado-Dyer R, Kass-Hout T, Prabhakaran S, Honda T, Liebeskind DS, Furie K. Direct Oral Anticoagulants Versus Warfarin in the Treatment of Cerebral Venous Thrombosis (ACTION-CVT): A Multicenter International Study. Stroke 2022, 53: 728-738. PMID: 35143325, DOI: 10.1161/strokeaha.121.037541.
- Giles J, Vellimana A, Adeoye O. Endovascular Treatment of Acute Stroke. Current Neurology And Neuroscience Reports 2022, 22: 83-91. PMID: 35098425, DOI: 10.1007/s11910-022-01168-9.
- Petersen NH, Kodali S, Meng C, Li F, Nguyen CK, Peshwe KU, Strander S, Silverman A, Kimmel A, Wang A, Anadani M, Almallouhi E, Spiotta AM, Kim JT, Giles JA, Keyrouz SG, Farooqui M, Zevallos C, Maier IL, Psychogios MN, Liman J, Riou-Comte N, Richard S, Gory B, Wolfe S, Brown PA, Fargen KM, Mistry EA, Fakhri H, Mistry AM, Wong KH, de Havenon A, Nascimento FA, Kan P, Matouk C, Ortega-Gutiérrez S, Sheth KN. Blood Pressure Trajectory Groups and Outcome After Endovascular Thrombectomy: A Multicenter Study. Stroke 2021, 53: 1216-1225. PMID: 34781705, PMCID: PMC8960326, DOI: 10.1161/strokeaha.121.034408.
- Akbik F, Alawieh A, Cawley CM, Howard BM, Tong FC, Nahab F, Saad H, Dimisko L, Mustroph C, Samuels OB, Pradilla G, Maier I, Goyal N, Starke RM, Rai A, Fargen KM, Psychogios MN, Jabbour P, De Leacy R, Giles J, Dumont TM, Kan P, Arthur AS, Crosa RJ, Gory B, Spiotta AM, Grossberg JA. Differential effect of mechanical thrombectomy and intravenous thrombolysis in atrial fibrillation associated stroke. Journal Of Neurointerventional Surgery 2021, 13: 883-888. PMID: 33318066, PMCID: PMC8377613, DOI: 10.1136/neurintsurg-2020-016720.
- Yaghi S, Mistry E, de Havenon A, Guerrero C, Nouh A, Liberman AL, Giles J, Liu A, Nagy M, Kaushal A, Azher I, Mac Grory B, Fakhri H, Espaillat K, Asad SD, Pasupuleti H, Martin H, Tan J, Veerasamy M, Esenwa C, Cheng N, Moncrieffe K, Moeini‐Naghani I, Siddu M, Scher E, Trivedi T, Wu T, Khan M, Keyrouz S, Furie K, Henninger N. Effect of Alteplase Use on Outcomes in Patients With Atrial Fibrillation: Analysis of the Initiation of Anticoagulation After Cardioembolic Stroke Study. Journal Of The American Heart Association 2021, 10: e020945. PMID: 34323120, PMCID: PMC8475683, DOI: 10.1161/jaha.121.020945.
- Holder D, Leeseberg K, Giles J, Lee J, Namazie S, Ford A. Central Triage of Acute Stroke Patients Across a Distributive Stroke Network Is Safe and Reduces Transfer Denials. Stroke 2021, 52: 2671-2675. PMID: 34154389, PMCID: PMC8316396, DOI: 10.1161/strokeaha.120.033018.
- Giles J, Balasetti V, Zazulia A. Non-Vitamin K Antagonist Oral Anticoagulants for the Treatment of Cerebral Venous Sinus Thrombosis: a Retrospective, Matched Cohort Analysis. Neurocritical Care 2021, 35: 783-788. PMID: 34046861, DOI: 10.1007/s12028-021-01244-x.
- Yaghi S, Henninger N, Giles JA, Guerrero C, Mistry E, Liberman AL, Asad D, Liu A, Nagy M, Kaushal A, Azher I, Mac Grory B, Fakhri H, Espaillat K, Pasupuleti H, Martin H, Tan J, Veerasamy M, Esenwa C, Cheng N, Moncrieffe K, Moeini-Naghani I, Siddu M, Scher E, Trivedi T, Furie KL, Keyrouz SG, Nouh A, de Havenon A, Khan M, Smith EE, Gurol ME. Ischaemic stroke on anticoagulation therapy and early recurrence in acute cardioembolic stroke: the IAC study. Journal Of Neurology Neurosurgery & Psychiatry 2021, 92: 1062-1067. PMID: 33903185, PMCID: PMC8448925, DOI: 10.1136/jnnp-2021-326166.
- Alawieh AM, Eid M, Anadani M, Sattur M, Maier IL, Feng W, Goyal N, Starke RM, Rai A, Fargen KM, Psychogios MN, De Leacy R, Grossberg JA, Keyrouz SG, Dumont TM, Kan P, Lena J, Liman J, Arthur AS, Elijovich L, Mccarthy DJ, Saini V, Wolfe SQ, Mocco J, Fifi JT, Nascimento FA, Giles JA, Allen M, Crosa R, Fox WC, Gory B, Spiotta AM. Thrombectomy Technique Predicts Outcome in Posterior Circulation Stroke-Insights from the STAR Collaboration. Neurosurgery 2020, 87: 982-991. PMID: 32433730, DOI: 10.1093/neuros/nyaa179.
- Hill E, El-Haj M, Giles J, Fox I. Using electrodiagnostics to define injury patterns amenable to nerve transfer surgery in tetraplegia: an illustrative case report. Spinal Cord Series And Cases 2020, 6: 78. PMID: 32826861, PMCID: PMC7442626, DOI: 10.1038/s41394-020-00325-x.
- Yaghi S, Mistry E, Liberman AL, Giles J, Asad SD, Liu A, Nagy M, Kaushal A, Azher I, Mac Grory B, Fakhri H, Brown Espaillat K, Pasupuleti H, Martin H, Tan J, Veerasamy M, Esenwa C, Cheng N, Moncrieffe K, Moeini-Naghani I, Siddu M, Scher E, Trivedi T, Lord A, Furie K, Keyrouz S, Nouh A, Leon Guerrero CR, de Havenon A, Khan M, Henninger N. Anticoagulation Type and Early Recurrence in Cardioembolic Stroke. Stroke 2020, 51: 2724-2732. PMID: 32757753, PMCID: PMC7484360, DOI: 10.1161/strokeaha.120.028867.
- Yaghi S, Trivedi T, Henninger N, Giles J, Liu A, Nagy M, Kaushal A, Azher I, Mac Grory B, Fakhri H, Espaillat K, Asad S, Pasupuleti H, Martin H, Tan J, Veerasamy M, Liberman A, Esenwa C, Cheng N, Moncrieffe K, Moeini‐Naghani I, Siddu M, Scher E, Guerrero C, Khan M, Nouh A, Mistry E, Keyrouz S, Furie K. Anticoagulation Timing in Cardioembolic Stroke and Recurrent Event Risk. Annals Of Neurology 2020, 88: 807-816. PMID: 32656768, PMCID: PMC8259451, DOI: 10.1002/ana.25844.
- Yaghi S, Liberman AL, Henninger N, Grory BM, Nouh A, Scher E, Giles J, Liu A, Nagy M, Kaushal A, Azher I, Fakhri H, Espaillat KB, Asad SD, Pasupuleti H, Martin H, Tan J, Veerasamy M, Esenwa C, Cheng N, Moncrieffe K, Moeini-Naghani I, Siddu M, Trivedi T, Ishida K, Frontera J, Lord A, Furie K, Keyrouz S, de Havenon A, Mistry E, Leon Guerrero CR, Khan M. Factors associated with therapeutic anticoagulation status in patients with ischemic stroke and atrial fibrillation. Journal Of Stroke And Cerebrovascular Diseases 2020, 29: 104888. PMID: 32414583, PMCID: PMC8207529, DOI: 10.1016/j.jstrokecerebrovasdis.2020.104888.
- Yaghi S, Henninger N, Scher E, Giles J, Liu A, Nagy M, Kaushal A, Azher I, Mac Grory B, Fakhri H, Espaillat K, Asad S, Pasupuleti H, Martin H, Tan J, Veerasamy M, Liberman A, Esenwa C, Cheng N, Moncrieffe K, Moeini-Naghani I, Siddu M, Trivedi T, Guerrero C, Khan M, Nouh A, Mistry E, Keyrouz S, Furie K. Early ischaemic and haemorrhagic complications after atrial fibrillation-related ischaemic stroke: analysis of the IAC study. Journal Of Neurology Neurosurgery & Psychiatry 2020, 91: 750-755. PMID: 32404380, PMCID: PMC8179007, DOI: 10.1136/jnnp-2020-323041.
- Anadani M, Arthur A, Tsivgoulis G, Simpson K, Alawieh A, Orabi Y, Goyal N, Alexandrov A, Maier I, Psychogios M, Liman J, Brinton D, Swisher C, Shah S, Inamullah O, Keyrouz S, Kansagra A, Allen M, Giles J, Wolfe S, Fargen K, Gory B, De Marini P, Kan P, Nascimento F, Almallouhi E, Petersen N, Kodali S, Rahman S, Richard S, Spiotta A. Blood Pressure Goals and Clinical Outcomes after Successful Endovascular Therapy: A Multicenter Study. Annals Of Neurology 2020, 87: 830-839. PMID: 32187711, DOI: 10.1002/ana.25716.
- Anadani M, Arthur AS, Alawieh A, Orabi Y, Alexandrov A, Goyal N, Psychogios MN, Maier I, Kim JT, Keyrouz SG, de Havenon A, Petersen NH, Pandhi A, Swisher CB, Inamullah O, Liman J, Kodali S, Giles JA, Allen M, Wolfe SQ, Tsivgoulis G, Cagle BA, Oravec CS, Gory B, De Marini P, Kan P, Rahman S, Richard S, Nascimento FA, Spiotta A. Blood pressure reduction and outcome after endovascular therapy with successful reperfusion: a multicenter study. Journal Of NeuroInterventional Surgery 2019, 12: 932-936. PMID: 31806668, PMCID: PMC7998040, DOI: 10.1136/neurintsurg-2019-015561.
- Anadani M, Orabi M, Alawieh A, Goyal N, Alexandrov A, Petersen N, Kodali S, Maier I, Psychogios M, Swisher C, Inamullah O, Kansagra A, Giles J, Wolfe S, Singh J, Gory B, De Marini P, Kan P, Nascimento F, Freire L, Pandhi A, Mitchell H, Kim J, Fargen K, Al Kasab S, Liman J, Rahman S, Allen M, Richard S, Spiotta A. Blood Pressure and Outcome After Mechanical Thrombectomy With Successful Revascularization. Stroke 2019, 50: 2448-2454. PMID: 31318633, DOI: 10.1161/strokeaha.118.024687.
- Tamachi S, Giles J, Dornan T, Hill E. “You understand that whole big situation they’re in”: interpretative phenomenological analysis of peer-assisted learning. BMC Medical Education 2018, 18: 197. PMID: 30107801, PMCID: PMC6092812, DOI: 10.1186/s12909-018-1291-2.
- Giles J, Greenhalgh A, Denes A, Nieswandt B, Coutts G, McColl B, Allan S. Neutrophil infiltration to the brain is platelet‐dependent, and is reversed by blockade of platelet GPIbα. Immunology 2018, 154: 322-328. PMID: 29325217, PMCID: PMC5979746, DOI: 10.1111/imm.12892.
- Giles J, Hill E. Examining our hidden curricula: powerful, visible, gendered and discriminatory. Medical Education 2015, 49: 244-246. PMID: 25693983, DOI: 10.1111/medu.12664.
- Giles J, Greenhalgh A, Davies C, Denes A, Shaw T, Coutts G, Rothwell N, McColl B, Allan S. Requirement for interleukin‐1 to drive brain inflammation reveals tissue‐specific mechanisms of innate immunity. European Journal Of Immunology 2014, 45: 525-530. PMID: 25367678, PMCID: PMC4357393, DOI: 10.1002/eji.201444748.
- Giles J, Hill E. Looking more reflexively at surgical culture. Medical Education 2014, 48: 1245-1245. PMID: 25413918, DOI: 10.1111/medu.12611.
- Hill E, Giles J. Career decisions and gender: the illusion of choice? Perspectives On Medical Education 2014, 3: 151-154. PMID: 24957796, PMCID: PMC4078050, DOI: 10.1007/s40037-014-0128-x.
- Girard S, Brough D, Lopez-Castejon G, Giles J, Rothwell N, Allan S. Microglia and macrophages differentially modulate cell death after brain injury caused by oxygen‐glucose deprivation in organotypic brain slices. Glia 2013, 61: 813-824. PMID: 23404620, PMCID: PMC3644876, DOI: 10.1002/glia.22478.
- Hill E, Giles J, Dornan T. Teaching in a busy clinic. Practical Neurology 2012, 12: 376. PMID: 23144301, DOI: 10.1136/practneurol-2012-000267.
- Luheshi N, Giles J, Lopez‐Castejon G, Brough D. Sphingosine regulates the NLRP3‐inflammasome and IL‐1β release from macrophages. European Journal Of Immunology 2011, 42: 716-725. PMID: 22105559, PMCID: PMC3491674, DOI: 10.1002/eji.201142079.
- Giles J, Greenhalgh A, Denes A, Thornton P, Rothwell N, McColl B, Allan S. 48 Endovascular inflammation may occur via tissue-specific mechanisms. Heart 2011, 97: e7. DOI: 10.1136/heartjnl-2011-300920b.48.
- Hill E, Liuzzi F, Giles J. Peer‐assisted learning from three perspectives: student, tutor and co‐ordinator. The Clinical Teacher 2010, 7: 244-246. PMID: 21134199, DOI: 10.1111/j.1743-498x.2010.00399.x.
- Giles J. Clinical neuroscience attachments: a student’s view of ‘neurophobia’. The Clinical Teacher 2010, 7: 9-13. PMID: 21134136, DOI: 10.1111/j.1743-498x.2009.00330.x.
- Giles J. Surgical training and the European Working Time Directive: The role of informal workplace learning. International Journal Of Surgery 2010, 8: 179-180. PMID: 20144752, DOI: 10.1016/j.ijsu.2010.01.011.
- Yale Neurology - GuilfordYale Medicine Multispecialty800 Boston Post RoadGuilford, CT 06437
- Yale Neurology - GuilfordYale Medicine Multispecialty800 Boston Post RoadGuilford, CT 06437