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I. George Miller Jr, MD

Pediatrics, Pediatric Infectious Diseases, Internal Medicine, Medical Oncology
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Patient type treated
Child
Accepting new patients
Yes
Referral required
From physicians only
Board Certified in
Internal Medicine

Biography

Dr. Miller’s laboratory studies the mechanisms underlying the switch between latency and lytic replication of two oncogenic herpesviruses, Epstein-Barr virus and Kaposi’s sarcoma-associated herpesvirus. Current experiments explore how viral and cellular transcription factors that selectively bind to methylated DNA control expression of viral and cellular genes, how cellular gene expression is selectively inhibited while viral gene expression is enhanced, and how viral DNA replication is regulated by cellular proteins. Recent studies focus on a new class of anti-viral agents that inhibit reactivation of Epstein-Barr virus from latency into lytic infection.

Titles

  • John F. Enders Professor of Pediatrics (Infectious Disease) and Professor of Epidemiology (Microbial Diseases) and of Molecular Biophysics and Biochemistry
  • Section Chief, Pediatric Infectious Diseases

Education & Training

  • Research Fellow
    Children's Hospital, Boston (1969)
  • Research Fellow
    Harvard Medical School (1969)
  • AB
    Harvard College (1968)
  • Intern & Assistant Resident
    University Hospital, Cleveland (1964)
  • MD
    Harvard Medical School (1962)

Additional Information

  • Yale Pediatric Infectious Diseases
    Yale New Haven Children's Hospital
    1 Park Street, Ste West Pavilion - 2nd Floor
    New Haven, CT, 06504
  • Yale Pediatric Infectious Disease
    Yale New Haven Hospital
    20 York Street
    New Haven, CT, 06510