- Yale New Haven Children's Hospital Specialty CentersYale New Haven Hospital - West Pavilion1 Park Street, Wing West Pavilion Ste 2nd FloorNew Haven, CT 06510
- Pediatric Specialty Center747 Belden AvenueSte 1st FloorNorwalk, CT 06850
- Yale Surgery Pediatric SurgeryTrumbull Pediatric Specialty Center5520 Park AvenueTrumbull, CT 06611
- Pediatric Specialty CenterOld Saybrook Medical Center633 Middlesex TurnpikeOld Saybrook, CT 06475
David Stitelman, MD
Biography
David H. Stitelman, MD, says he considers it an honor to work to improve the lives and health of children. As a pediatric surgeon who treats children of all ages, Dr. Stitelman is often able to make an impact on a child’s life soon after he or she is born.
Dr. Stitelman is the surgical director of the Fetal Care Center, a joint program of Yale Medicine and Yale New Haven Children’s Hospital. At the Fetal Care Center, a multidisciplinary team of pediatric specialists, obstetricians and neonatologists work with families whose child has been diagnosed before birth with a condition that requires treatment.
“We spend a great deal of time explaining to families the medical and surgical issues their child faces,” Dr. Stitelman says. “We want them to understand, and we follow our patients long term to assure they are thriving after they go home.”
Dr. Stitelman is also an assistant professor of pediatric surgery at Yale School of Medicine. His research is focused on prenatal therapy, with the hope of treating and curing genetic and structural diseases before a child is born.
Titles
- Associate Professor of Surgery (Pediatrics)
Education & Training
- FellowshipChildren's Hospital of Philadelphia (2013)
- ResidencyHospital of the University of Pennsylvania (2011)
- MDUniversity of Pennsylvania Medical School (2004)
Additional Information
- C Elton Cahow Teaching Award: Yale Department of Surgery (2018)
- The Francis Gilman Blake Award: Yale School of Medicine (2017)
- AB of Surgery, Pediatric Surgery (2015)
- AB of Surgery, Surgery General (2012)
- Ricciardi A, Barone C, Putman R, Quijano E, Gupta A, Nguyen R, Mandl H, Piotrowski-Daspit A, Lopez-Giraldez F, Luks V, Freedman-Weiss M, Farrelly J, Ahle S, Lynn A, Glazer P, Saltzman W, Stitelman D, Egan M. Systemic in utero gene editing as a treatment for cystic fibrosis. Proceedings Of The National Academy Of Sciences Of The United States Of America 2025, 122: e2418731122. PMID: 40493185, PMCID: PMC12184489, DOI: 10.1073/pnas.2418731122.
- Haynes C, Thaxton C, Shaughnessy M, Stitelman D. Atypical presentation of occult congenital diaphragmatic hernia as intermittent obstructive symptoms: A case report. Journal Of Pediatric Surgery Case Reports 2025, 117: 103018. DOI: 10.1016/j.epsc.2025.103018.
- Lynn A, Shin K, Eaton D, Rose M, Zhang X, Ene M, Grundler J, Deschenes E, Rivero R, Bracaglia L, Glazer P, Stitelman D, Saltzman W. Investigation of the protein corona and biodistribution profile of polymeric nanoparticles for intra-amniotic delivery. Biomaterials 2025, 320: 123238. PMID: 40064138, PMCID: PMC11972154, DOI: 10.1016/j.biomaterials.2025.123238.
- Eaton D, Lynn A, Surprenant J, Deschenes E, Guerra M, Rivero R, Yung N, O'Connor M, Glazer P, Bahtiyar M, Saltzman W, Stitelman D. Biodistribution of Polymeric Nanoparticles following in utero Delivery to a Nonhuman Primate. Biomedicine Hub 2024, 10: 543138. PMID: 39845408, PMCID: PMC11753793, DOI: 10.1159/000543138.
- Rivero R, Brown L, Flom E, Morton C, Esdaille C, Jernigan E, Lui F, Stitelman D. Evaluating Operative Exposure for Medical Students in the Era of Virtual Learning: A Single-Institution Experience. Journal Of Surgical Education 2024, 81: 1346-1351. PMID: 39163718, DOI: 10.1016/j.jsurg.2024.07.015.
- Rivero R, Stitelman D. Prenatal Therapy for Congenital Diaphragmatic Hernia and Myelomeningocele: Advances in Particle-Based Delivery. Current Stem Cell Reports 2024, 10: 51-57. DOI: 10.1007/s40778-024-00237-8.
- Lynn A, Glazer P, Saltzman W, Stitelman D. The Technical and Ethical Framework of Fetal Therapy: Past and Current Advances. Current Stem Cell Reports 2024, 10: 30-36. DOI: 10.1007/s40778-024-00235-w.
- Roth L, Smith A, Buza N, Coons B, Stitelman D, Vash-Margita A. Ovarian Leydig Cell Tumor Associated with Recurrent Torsion and Virilization in an Adolescent Patient. Journal Of Pediatric And Adolescent Gynecology 2023, 37: 217-219. PMID: 38110028, DOI: 10.1016/j.jpag.2023.11.014.
- Ullrich S, Yung N, Bauer-Pisani T, Maassel N, Guerra M, Freedman-Weiss M, Ahle S, Ricciardi A, Sauler M, Saltzman W, Piotrowski-Daspit A, Stitelman D. In utero delivery of miRNA induces epigenetic alterations and corrects pulmonary pathology in congenital diaphragmatic hernia. Molecular Therapy - Nucleic Acids 2023, 32: 594-602. PMID: 37200861, PMCID: PMC10185702, DOI: 10.1016/j.omtn.2023.04.018.
- Maassel N, Stitelman D. Cholecystitis and Gallstone Disease. 2022, 837-841. DOI: 10.1007/978-3-031-07524-7_90.
- Herzeg A, Almeida‐Porada G, Charo RA, David AL, Gonzalez‐Velez J, Gupta N, Lapteva L, Lianoglou B, Peranteau W, Porada C, Sanders SJ, Sparks TN, Stitelman DH, Struble E, Sumner CJ, MacKenzie TC. Prenatal Somatic Cell Gene Therapies: Charting a Path Toward Clinical Applications (Proceedings of the CERSI‐FDA Meeting). The Journal Of Clinical Pharmacology 2022, 62: s36-s52. PMID: 36106778, PMCID: PMC9547535, DOI: 10.1002/jcph.2127.
- Luks VL, Mandl H, DiRito J, Barone C, Freedman-Weiss MR, Ricciardi AS, Tietjen GG, Egan ME, Saltzman WM, Stitelman DH. Surface conjugation of antibodies improves nanoparticle uptake in bronchial epithelial cells. PLOS ONE 2022, 17: e0266218. PMID: 35385514, PMCID: PMC8986008, DOI: 10.1371/journal.pone.0266218.
- Maassel NL, Wu DH, Yung NK, Bauer-Pisani T, Elizabeth Guerra M, Ullrich SJ, Mark Saltzman W, Stitelman DH. Intra-amniotic Injection of Poly(lactic-co-glycolic Acid) Microparticles Loaded with Growth Factor: Effect on Tissue Coverage and Cellular Apoptosis in the Rat Model of Myelomeningocele. Journal Of The American College Of Surgeons 2022, 234: 1010-1019. PMID: 35703790, DOI: 10.1097/xcs.0000000000000156.
- Maassel N, Saccary A, Solomon D, Stitelman D, Xu Y, Li F, Christison-Lagay E, Dodington J. Firework-related injuries treated at emergency departments in the United States during the COVID-19 pandemic in 2020 compared to 2018–2019. Injury Epidemiology 2021, 8: 65. PMID: 34758871, PMCID: PMC8579722, DOI: 10.1186/s40621-021-00358-2.
- Maassel NL, Guerra ME, Solomon DG, Stitelman DH. Institutional Variation in Gastrostomy Tube Placement After Duodenal Atresia Repair in Children With Trisomy 21. Journal Of Pediatric Gastroenterology And Nutrition 2021, 73: 560-565. PMID: 34238829, DOI: 10.1097/mpg.0000000000003227.
- Maassel N, Farrelly J, Coman D, Freedman-Weiss M, Ahle S, Ullrich S, Yung N, Hyder F, Stitelman D. Diffusion weighted imaging as a biomarker of retinoic acid induced myelomeningocele. PLOS ONE 2021, 16: e0253583. PMID: 34191842, PMCID: PMC8244849, DOI: 10.1371/journal.pone.0253583.
- Yung NK, Maassel NL, Ullrich SJ, Ricciardi AS, Stitelman DH. A narrative review of in utero gene therapy: advances, challenges, and future considerations. Translational Pediatrics 2021, 10: 1486496-1481496. PMID: 34189107, PMCID: PMC8192997, DOI: 10.21037/tp-20-89.
- Freedman-Weiss MR, Wu D, Maassel N, Ullrich SJ, Ahle SL, Roberts K, Farrelly JS, Buzzelli G, Saltzman WM, Stitelman DH. Engineering alginate microparticles for optimized accumulation in fetal rat myelomeningocele. Journal Of Pediatric Surgery 2021, 57: 544-550. PMID: 33933264, DOI: 10.1016/j.jpedsurg.2021.03.060.
- Wilpers A, Bahtiyar MO, Stitelman D, Batten J, Calix RX, Chase V, Yung N, Maassel N, Novick G. The parental journey of fetal care: a systematic review and metasynthesis. American Journal Of Obstetrics & Gynecology MFM 2021, 3: 100320. PMID: 33493706, DOI: 10.1016/j.ajogmf.2021.100320.
- Ullrich SJ, Freedman-Weiss M, Ahle S, Mandl HK, Piotrowski-Daspit AS, Roberts K, Yung N, Maassel N, Bauer-Pisani T, Ricciardi AS, Egan ME, Glazer PM, Saltzman WM, Stitelman DH. Nanoparticles for delivery of agents to fetal lungs. Acta Biomaterialia 2021, 123: 346-353. PMID: 33484911, PMCID: PMC7962939, DOI: 10.1016/j.actbio.2021.01.024.
- Rubinstein J, Farrelly J, Stitelman D, Christison-Lagay E. Anomalies of the Gastrointestinal Tract. 2020, 179-204. DOI: 10.1007/978-3-030-55660-0_9.
- Eysenbach LM, Caty MG, Christison-Lagay ER, Cowles RA, Dillon B, Goodman TR, Ozgediz DE, Stitelman DH, Solomon DG. Outcomes following adoption of a standardized protocol for abscess drain management in pediatric appendicitis. Journal Of Pediatric Surgery 2020, 56: 43-46. PMID: 33143877, DOI: 10.1016/j.jpedsurg.2020.09.050.
- Cochran ED, Lazow SP, Kim AG, Burkhalter LS, Frost NW, Stitelman D, Davis J, Santiago-Munoz P, Buchmiller TL, Perrone EE, Schindel DT. The in-utero diagnosis of choledochal cyst: can postnatal imaging predict benefit from early surgical intervention? The Journal Of Maternal-Fetal & Neonatal Medicine 2020, 35: 1070-1074. PMID: 32188329, DOI: 10.1080/14767058.2020.1742320.
- Freedman-Weiss M, Stitelman D. Minimally Invasive Fetal Therapy for Myelomeningocele. Current Stem Cell Reports 2020, 6: 1-5. DOI: 10.1007/s40778-020-00167-1.
- Freedman-Weiss MR, Chiu AS, Worhunsky D, Manchisi A, Torres-Maldonado I, Sagnella L, Caty MG, Cowles RA, Ozgediz DE, Christison-Lagay ER, Solomon DG, Stitelman DH. An Evidence-Based Guideline Supporting Restricted Opioid Prescription after Pediatric Appendectomy. Journal Of Pediatric Surgery 2019, 55: 106-111. PMID: 31699433, DOI: 10.1016/j.jpedsurg.2019.09.063.
- Tuzovic L, Copel JA, Stitelman DH, Levit O, Bahtiyar MO. Utility of Fetal Cardiac Axis and Cardiac Position Assessment in Predicting Neonatal Respiratory Morbidity in Fetal Congenital Lung Lesions. Journal Of Ultrasound In Medicine 2019, 38: 2361-2372. PMID: 30653685, DOI: 10.1002/jum.14931.
- Freedman-Weiss MR, Chiu A, Solomon DG, Christison-Lagay ER, Ozgediz DE, Cowles RA, Caty MG, Stitelman DH. Opioid Prescribing Habits of General Versus Pediatric Surgeons After Uncomplicated Laparoscopic Appendectomy. Journal Of Surgical Research 2018, 235: 404-409. PMID: 30691822, DOI: 10.1016/j.jss.2018.09.085.
- Greig CJ, Keiser AM, Cleary MA, Stitelman DH, Christison-Lagay ER, Ozgediz DE, Solomon DG, Caty MG, Cowles RA. Routine postnatal chest x-ray and intensive care admission are unnecessary for a majority of infants with congenital lung malformations. Journal Of Pediatric Surgery 2018, 54: 670-674. PMID: 30503193, DOI: 10.1016/j.jpedsurg.2018.10.063.
- Farrelly JS, Bianchi AH, Ricciardi AS, Buzzelli GL, Ahle SL, Freedman-Weiss MR, Luks VL, Saltzman WM, Stitelman DH. Alginate microparticles loaded with basic fibroblast growth factor induce tissue coverage in a rat model of myelomeningocele. Journal Of Pediatric Surgery 2018, 54: 80-85. PMID: 30414695, DOI: 10.1016/j.jpedsurg.2018.10.031.
- Ricciardi AS, Bahal R, Farrelly JS, Quijano E, Bianchi AH, Luks VL, Putman R, López-Giráldez F, Coşkun S, Song E, Liu Y, Hsieh WC, Ly DH, Stitelman DH, Glazer PM, Saltzman WM. In utero nanoparticle delivery for site-specific genome editing. Nature Communications 2018, 9: 2481. PMID: 29946143, PMCID: PMC6018676, DOI: 10.1038/s41467-018-04894-2.
- Farrelly J, Weiss R, Copel J, Porto A, Ahle S, Luks V, McGrath J, Stitelman D. An atypical case of megacystis microcolon intestinal hypoperistalsis syndrome with extended survival and consistent bowel function. Journal Of Pediatric Surgery Case Reports 2018, 30: 48-51. DOI: 10.1016/j.epsc.2017.11.010.
- Ahle SL, Cardella JA, Cleary MA, Stitelman DH, Sarac TP, Caty MG. Repair of a mycotic abdominal aortic aneurysm in a neonate using an everted jugular vein patch. Journal Of Vascular Surgery Cases And Innovative Techniques 2017, 3: 218-220. PMID: 29349429, PMCID: PMC5765176, DOI: 10.1016/j.jvscit.2017.08.003.
- Farrelly JS, Clemons C, Witkins S, Hall W, Christison-Lagay ER, Ozgediz DE, Cowles RA, Stitelman DH, Caty MG. Surgical tray optimization as a simple means to decrease perioperative costs. Journal Of Surgical Research 2017, 220: 320-326. PMID: 29180198, DOI: 10.1016/j.jss.2017.06.029.
- Farrelly JS, Stitelman DH. Complications in pediatric enteral and vascular access. Seminars In Pediatric Surgery 2016, 25: 371-379. PMID: 27989361, DOI: 10.1053/j.sempedsurg.2016.10.006.
- Farrelly J, Cleary M, Weiss R, Morotti R, Stitelman D. Acquired seminal vesicle cyst in a teenager with a urethral stricture of unknown etiology. Journal Of Pediatric Surgery Case Reports 2016, 7: 8-12. DOI: 10.1016/j.epsc.2016.01.002.
- Stitelman DH, Brazelton TR, Endo M, Bora A, Traas J, Zoltick PW, Flake AW. Life-Long Transgene Expression in Skeletal Muscle Without Transduction of Satellite Cells Following Embryonic Myogenic Progenitor Transduction by Lentivirus Administered in Utero. Stem Cells And Development 2015, 24: 1878-1887. PMID: 25915576, PMCID: PMC4533031, DOI: 10.1089/scd.2014.0585.
- Luks V, Moores C, Villalona G, Stitelman D, Caty M. Successful non-operative management of a contained tracheal tear following iatrogenic endotracheal tube injury. Journal Of Pediatric Surgery Case Reports 2014, 2: 524-526. DOI: 10.1016/j.epsc.2014.10.016.
- Stitelman DH, Brazelton T, Bora A, Traas J, Merianos D, Limberis M, Davey M, Flake AW. Developmental stage determines efficiency of gene transfer to muscle satellite cells by in utero delivery of adeno-associated virus vector serotype 2/9. Molecular Therapy — Methods & Clinical Development 2014, 1: 14040. PMID: 26015979, PMCID: PMC4362369, DOI: 10.1038/mtm.2014.40.
- Bermudez D, Herdrich B, Stitelman D, Radu A, Li H, Zoltick P, Mitchell M. Increased epithelial stem cell migration in vivo in response to stem cell factor-1. Journal Of The American College Of Surgeons 2010, 211: s93. DOI: 10.1016/j.jamcollsurg.2010.06.246.
- Stitelman DH, Endo M, Bora A, Muvarak N, Zoltick PW, Flake AW, Brazelton TR. Robust In Vivo Transduction of Nervous System and Neural Stem Cells by Early Gestational Intra Amniotic Gene Transfer Using Lentiviral Vector. Molecular Therapy 2010, 18: 1615-1623. PMID: 20571539, PMCID: PMC2956924, DOI: 10.1038/mt.2010.125.
- Allukian M, Herdrich B, Bermudez D, Stitelman D, Chin B, Davey M, Gorman J, Gorman R, Liechty K. Restoration of Function Following in Utero Fetal MI Is Associated with Increased Cardiac Progenitor Cell Recruitment. Journal Of Surgical Research 2010, 158: 307. DOI: 10.1016/j.jss.2009.11.379.
- Endo M, Henriques-Coelho T, Zoltick PW, Stitelman DH, Peranteau WH, Radu A, Flake AW. The developmental stage determines the distribution and duration of gene expression after early intra-amniotic gene transfer using lentiviral vectors. Gene Therapy 2009, 17: 61-71. PMID: 19727133, DOI: 10.1038/gt.2009.115.
- Stitelman D, Bora A, Jeremy T, Merianos D, Flake A, Brazelton T. Efficient gene transfer to muscle satellite cells by in utero intravenous delivery of adeno-associated viral vector. Journal Of The American College Of Surgeons 2009, 209: s124. DOI: 10.1016/j.jamcollsurg.2009.06.309.
- Stitelman D, Masayuki E, Zoltick P, Brazelton T, Flake A. Gene transfer to progenitor cells of the central nervous system by early intraamniotic delivery of lentiviral vector. Journal Of The American College Of Surgeons 2008, 207: s103. DOI: 10.1016/j.jamcollsurg.2008.06.263.
- Keswani S, Parvadia J, Stitelman D, Kozin E, Radu A, Alaee D, Zoltick P, Crombleholme T. Mechanism of angiopoietin-1 mediated endothelial progenitor cell recruitment in wound healing. Journal Of The American College Of Surgeons 2004, 199: 60. DOI: 10.1016/j.jamcollsurg.2004.05.124.
- Tuma J, Connors W, Stitelman D, Richert C. On the Effect of Covalently Appended Quinolones on Termini of DNA Duplexes. Journal Of The American Chemical Society 2002, 124: 4236-4246. PMID: 11960452, DOI: 10.1021/ja0125117.
- Haas T, Stitelman D, Davis S, Apte S, Madri J. Egr-1 Mediates Extracellular Matrix-driven Transcription of Membrane Type 1 Matrix Metalloproteinase in Endothelium*. Journal Of Biological Chemistry 1999, 274: 22679-22685. PMID: 10428849, DOI: 10.1074/jbc.274.32.22679.
- Yale New Haven Children's Hospital Specialty CentersYale New Haven Hospital - West Pavilion1 Park Street, Wing West Pavilion Ste 2nd FloorNew Haven, CT 06510
- Pediatric Specialty Center747 Belden AvenueSte 1st FloorNorwalk, CT 06850
- Yale Surgery Pediatric SurgeryTrumbull Pediatric Specialty Center5520 Park AvenueTrumbull, CT 06611
- Pediatric Specialty CenterOld Saybrook Medical Center633 Middlesex TurnpikeOld Saybrook, CT 06475
Biography
David H. Stitelman, MD, says he considers it an honor to work to improve the lives and health of children. As a pediatric surgeon who treats children of all ages, Dr. Stitelman is often able to make an impact on a child’s life soon after he or she is born.
Dr. Stitelman is the surgical director of the Fetal Care Center, a joint program of Yale Medicine and Yale New Haven Children’s Hospital. At the Fetal Care Center, a multidisciplinary team of pediatric specialists, obstetricians and neonatologists work with families whose child has been diagnosed before birth with a condition that requires treatment.
“We spend a great deal of time explaining to families the medical and surgical issues their child faces,” Dr. Stitelman says. “We want them to understand, and we follow our patients long term to assure they are thriving after they go home.”
Dr. Stitelman is also an assistant professor of pediatric surgery at Yale School of Medicine. His research is focused on prenatal therapy, with the hope of treating and curing genetic and structural diseases before a child is born.
Titles
- Associate Professor of Surgery (Pediatrics)
Education & Training
- FellowshipChildren's Hospital of Philadelphia (2013)
- ResidencyHospital of the University of Pennsylvania (2011)
- MDUniversity of Pennsylvania Medical School (2004)
Additional Information
- C Elton Cahow Teaching Award: Yale Department of Surgery (2018)
- The Francis Gilman Blake Award: Yale School of Medicine (2017)
- AB of Surgery, Pediatric Surgery (2015)
- AB of Surgery, Surgery General (2012)
- Ricciardi A, Barone C, Putman R, Quijano E, Gupta A, Nguyen R, Mandl H, Piotrowski-Daspit A, Lopez-Giraldez F, Luks V, Freedman-Weiss M, Farrelly J, Ahle S, Lynn A, Glazer P, Saltzman W, Stitelman D, Egan M. Systemic in utero gene editing as a treatment for cystic fibrosis. Proceedings Of The National Academy Of Sciences Of The United States Of America 2025, 122: e2418731122. PMID: 40493185, PMCID: PMC12184489, DOI: 10.1073/pnas.2418731122.
- Haynes C, Thaxton C, Shaughnessy M, Stitelman D. Atypical presentation of occult congenital diaphragmatic hernia as intermittent obstructive symptoms: A case report. Journal Of Pediatric Surgery Case Reports 2025, 117: 103018. DOI: 10.1016/j.epsc.2025.103018.
- Lynn A, Shin K, Eaton D, Rose M, Zhang X, Ene M, Grundler J, Deschenes E, Rivero R, Bracaglia L, Glazer P, Stitelman D, Saltzman W. Investigation of the protein corona and biodistribution profile of polymeric nanoparticles for intra-amniotic delivery. Biomaterials 2025, 320: 123238. PMID: 40064138, PMCID: PMC11972154, DOI: 10.1016/j.biomaterials.2025.123238.
- Eaton D, Lynn A, Surprenant J, Deschenes E, Guerra M, Rivero R, Yung N, O'Connor M, Glazer P, Bahtiyar M, Saltzman W, Stitelman D. Biodistribution of Polymeric Nanoparticles following in utero Delivery to a Nonhuman Primate. Biomedicine Hub 2024, 10: 543138. PMID: 39845408, PMCID: PMC11753793, DOI: 10.1159/000543138.
- Rivero R, Brown L, Flom E, Morton C, Esdaille C, Jernigan E, Lui F, Stitelman D. Evaluating Operative Exposure for Medical Students in the Era of Virtual Learning: A Single-Institution Experience. Journal Of Surgical Education 2024, 81: 1346-1351. PMID: 39163718, DOI: 10.1016/j.jsurg.2024.07.015.
- Rivero R, Stitelman D. Prenatal Therapy for Congenital Diaphragmatic Hernia and Myelomeningocele: Advances in Particle-Based Delivery. Current Stem Cell Reports 2024, 10: 51-57. DOI: 10.1007/s40778-024-00237-8.
- Lynn A, Glazer P, Saltzman W, Stitelman D. The Technical and Ethical Framework of Fetal Therapy: Past and Current Advances. Current Stem Cell Reports 2024, 10: 30-36. DOI: 10.1007/s40778-024-00235-w.
- Roth L, Smith A, Buza N, Coons B, Stitelman D, Vash-Margita A. Ovarian Leydig Cell Tumor Associated with Recurrent Torsion and Virilization in an Adolescent Patient. Journal Of Pediatric And Adolescent Gynecology 2023, 37: 217-219. PMID: 38110028, DOI: 10.1016/j.jpag.2023.11.014.
- Ullrich S, Yung N, Bauer-Pisani T, Maassel N, Guerra M, Freedman-Weiss M, Ahle S, Ricciardi A, Sauler M, Saltzman W, Piotrowski-Daspit A, Stitelman D. In utero delivery of miRNA induces epigenetic alterations and corrects pulmonary pathology in congenital diaphragmatic hernia. Molecular Therapy - Nucleic Acids 2023, 32: 594-602. PMID: 37200861, PMCID: PMC10185702, DOI: 10.1016/j.omtn.2023.04.018.
- Maassel N, Stitelman D. Cholecystitis and Gallstone Disease. 2022, 837-841. DOI: 10.1007/978-3-031-07524-7_90.
- Herzeg A, Almeida‐Porada G, Charo RA, David AL, Gonzalez‐Velez J, Gupta N, Lapteva L, Lianoglou B, Peranteau W, Porada C, Sanders SJ, Sparks TN, Stitelman DH, Struble E, Sumner CJ, MacKenzie TC. Prenatal Somatic Cell Gene Therapies: Charting a Path Toward Clinical Applications (Proceedings of the CERSI‐FDA Meeting). The Journal Of Clinical Pharmacology 2022, 62: s36-s52. PMID: 36106778, PMCID: PMC9547535, DOI: 10.1002/jcph.2127.
- Luks VL, Mandl H, DiRito J, Barone C, Freedman-Weiss MR, Ricciardi AS, Tietjen GG, Egan ME, Saltzman WM, Stitelman DH. Surface conjugation of antibodies improves nanoparticle uptake in bronchial epithelial cells. PLOS ONE 2022, 17: e0266218. PMID: 35385514, PMCID: PMC8986008, DOI: 10.1371/journal.pone.0266218.
- Maassel NL, Wu DH, Yung NK, Bauer-Pisani T, Elizabeth Guerra M, Ullrich SJ, Mark Saltzman W, Stitelman DH. Intra-amniotic Injection of Poly(lactic-co-glycolic Acid) Microparticles Loaded with Growth Factor: Effect on Tissue Coverage and Cellular Apoptosis in the Rat Model of Myelomeningocele. Journal Of The American College Of Surgeons 2022, 234: 1010-1019. PMID: 35703790, DOI: 10.1097/xcs.0000000000000156.
- Maassel N, Saccary A, Solomon D, Stitelman D, Xu Y, Li F, Christison-Lagay E, Dodington J. Firework-related injuries treated at emergency departments in the United States during the COVID-19 pandemic in 2020 compared to 2018–2019. Injury Epidemiology 2021, 8: 65. PMID: 34758871, PMCID: PMC8579722, DOI: 10.1186/s40621-021-00358-2.
- Maassel NL, Guerra ME, Solomon DG, Stitelman DH. Institutional Variation in Gastrostomy Tube Placement After Duodenal Atresia Repair in Children With Trisomy 21. Journal Of Pediatric Gastroenterology And Nutrition 2021, 73: 560-565. PMID: 34238829, DOI: 10.1097/mpg.0000000000003227.
- Maassel N, Farrelly J, Coman D, Freedman-Weiss M, Ahle S, Ullrich S, Yung N, Hyder F, Stitelman D. Diffusion weighted imaging as a biomarker of retinoic acid induced myelomeningocele. PLOS ONE 2021, 16: e0253583. PMID: 34191842, PMCID: PMC8244849, DOI: 10.1371/journal.pone.0253583.
- Yung NK, Maassel NL, Ullrich SJ, Ricciardi AS, Stitelman DH. A narrative review of in utero gene therapy: advances, challenges, and future considerations. Translational Pediatrics 2021, 10: 1486496-1481496. PMID: 34189107, PMCID: PMC8192997, DOI: 10.21037/tp-20-89.
- Freedman-Weiss MR, Wu D, Maassel N, Ullrich SJ, Ahle SL, Roberts K, Farrelly JS, Buzzelli G, Saltzman WM, Stitelman DH. Engineering alginate microparticles for optimized accumulation in fetal rat myelomeningocele. Journal Of Pediatric Surgery 2021, 57: 544-550. PMID: 33933264, DOI: 10.1016/j.jpedsurg.2021.03.060.
- Wilpers A, Bahtiyar MO, Stitelman D, Batten J, Calix RX, Chase V, Yung N, Maassel N, Novick G. The parental journey of fetal care: a systematic review and metasynthesis. American Journal Of Obstetrics & Gynecology MFM 2021, 3: 100320. PMID: 33493706, DOI: 10.1016/j.ajogmf.2021.100320.
- Ullrich SJ, Freedman-Weiss M, Ahle S, Mandl HK, Piotrowski-Daspit AS, Roberts K, Yung N, Maassel N, Bauer-Pisani T, Ricciardi AS, Egan ME, Glazer PM, Saltzman WM, Stitelman DH. Nanoparticles for delivery of agents to fetal lungs. Acta Biomaterialia 2021, 123: 346-353. PMID: 33484911, PMCID: PMC7962939, DOI: 10.1016/j.actbio.2021.01.024.
- Rubinstein J, Farrelly J, Stitelman D, Christison-Lagay E. Anomalies of the Gastrointestinal Tract. 2020, 179-204. DOI: 10.1007/978-3-030-55660-0_9.
- Eysenbach LM, Caty MG, Christison-Lagay ER, Cowles RA, Dillon B, Goodman TR, Ozgediz DE, Stitelman DH, Solomon DG. Outcomes following adoption of a standardized protocol for abscess drain management in pediatric appendicitis. Journal Of Pediatric Surgery 2020, 56: 43-46. PMID: 33143877, DOI: 10.1016/j.jpedsurg.2020.09.050.
- Cochran ED, Lazow SP, Kim AG, Burkhalter LS, Frost NW, Stitelman D, Davis J, Santiago-Munoz P, Buchmiller TL, Perrone EE, Schindel DT. The in-utero diagnosis of choledochal cyst: can postnatal imaging predict benefit from early surgical intervention? The Journal Of Maternal-Fetal & Neonatal Medicine 2020, 35: 1070-1074. PMID: 32188329, DOI: 10.1080/14767058.2020.1742320.
- Freedman-Weiss M, Stitelman D. Minimally Invasive Fetal Therapy for Myelomeningocele. Current Stem Cell Reports 2020, 6: 1-5. DOI: 10.1007/s40778-020-00167-1.
- Freedman-Weiss MR, Chiu AS, Worhunsky D, Manchisi A, Torres-Maldonado I, Sagnella L, Caty MG, Cowles RA, Ozgediz DE, Christison-Lagay ER, Solomon DG, Stitelman DH. An Evidence-Based Guideline Supporting Restricted Opioid Prescription after Pediatric Appendectomy. Journal Of Pediatric Surgery 2019, 55: 106-111. PMID: 31699433, DOI: 10.1016/j.jpedsurg.2019.09.063.
- Tuzovic L, Copel JA, Stitelman DH, Levit O, Bahtiyar MO. Utility of Fetal Cardiac Axis and Cardiac Position Assessment in Predicting Neonatal Respiratory Morbidity in Fetal Congenital Lung Lesions. Journal Of Ultrasound In Medicine 2019, 38: 2361-2372. PMID: 30653685, DOI: 10.1002/jum.14931.
- Freedman-Weiss MR, Chiu A, Solomon DG, Christison-Lagay ER, Ozgediz DE, Cowles RA, Caty MG, Stitelman DH. Opioid Prescribing Habits of General Versus Pediatric Surgeons After Uncomplicated Laparoscopic Appendectomy. Journal Of Surgical Research 2018, 235: 404-409. PMID: 30691822, DOI: 10.1016/j.jss.2018.09.085.
- Greig CJ, Keiser AM, Cleary MA, Stitelman DH, Christison-Lagay ER, Ozgediz DE, Solomon DG, Caty MG, Cowles RA. Routine postnatal chest x-ray and intensive care admission are unnecessary for a majority of infants with congenital lung malformations. Journal Of Pediatric Surgery 2018, 54: 670-674. PMID: 30503193, DOI: 10.1016/j.jpedsurg.2018.10.063.
- Farrelly JS, Bianchi AH, Ricciardi AS, Buzzelli GL, Ahle SL, Freedman-Weiss MR, Luks VL, Saltzman WM, Stitelman DH. Alginate microparticles loaded with basic fibroblast growth factor induce tissue coverage in a rat model of myelomeningocele. Journal Of Pediatric Surgery 2018, 54: 80-85. PMID: 30414695, DOI: 10.1016/j.jpedsurg.2018.10.031.
- Ricciardi AS, Bahal R, Farrelly JS, Quijano E, Bianchi AH, Luks VL, Putman R, López-Giráldez F, Coşkun S, Song E, Liu Y, Hsieh WC, Ly DH, Stitelman DH, Glazer PM, Saltzman WM. In utero nanoparticle delivery for site-specific genome editing. Nature Communications 2018, 9: 2481. PMID: 29946143, PMCID: PMC6018676, DOI: 10.1038/s41467-018-04894-2.
- Farrelly J, Weiss R, Copel J, Porto A, Ahle S, Luks V, McGrath J, Stitelman D. An atypical case of megacystis microcolon intestinal hypoperistalsis syndrome with extended survival and consistent bowel function. Journal Of Pediatric Surgery Case Reports 2018, 30: 48-51. DOI: 10.1016/j.epsc.2017.11.010.
- Ahle SL, Cardella JA, Cleary MA, Stitelman DH, Sarac TP, Caty MG. Repair of a mycotic abdominal aortic aneurysm in a neonate using an everted jugular vein patch. Journal Of Vascular Surgery Cases And Innovative Techniques 2017, 3: 218-220. PMID: 29349429, PMCID: PMC5765176, DOI: 10.1016/j.jvscit.2017.08.003.
- Farrelly JS, Clemons C, Witkins S, Hall W, Christison-Lagay ER, Ozgediz DE, Cowles RA, Stitelman DH, Caty MG. Surgical tray optimization as a simple means to decrease perioperative costs. Journal Of Surgical Research 2017, 220: 320-326. PMID: 29180198, DOI: 10.1016/j.jss.2017.06.029.
- Farrelly JS, Stitelman DH. Complications in pediatric enteral and vascular access. Seminars In Pediatric Surgery 2016, 25: 371-379. PMID: 27989361, DOI: 10.1053/j.sempedsurg.2016.10.006.
- Farrelly J, Cleary M, Weiss R, Morotti R, Stitelman D. Acquired seminal vesicle cyst in a teenager with a urethral stricture of unknown etiology. Journal Of Pediatric Surgery Case Reports 2016, 7: 8-12. DOI: 10.1016/j.epsc.2016.01.002.
- Stitelman DH, Brazelton TR, Endo M, Bora A, Traas J, Zoltick PW, Flake AW. Life-Long Transgene Expression in Skeletal Muscle Without Transduction of Satellite Cells Following Embryonic Myogenic Progenitor Transduction by Lentivirus Administered in Utero. Stem Cells And Development 2015, 24: 1878-1887. PMID: 25915576, PMCID: PMC4533031, DOI: 10.1089/scd.2014.0585.
- Luks V, Moores C, Villalona G, Stitelman D, Caty M. Successful non-operative management of a contained tracheal tear following iatrogenic endotracheal tube injury. Journal Of Pediatric Surgery Case Reports 2014, 2: 524-526. DOI: 10.1016/j.epsc.2014.10.016.
- Stitelman DH, Brazelton T, Bora A, Traas J, Merianos D, Limberis M, Davey M, Flake AW. Developmental stage determines efficiency of gene transfer to muscle satellite cells by in utero delivery of adeno-associated virus vector serotype 2/9. Molecular Therapy — Methods & Clinical Development 2014, 1: 14040. PMID: 26015979, PMCID: PMC4362369, DOI: 10.1038/mtm.2014.40.
- Bermudez D, Herdrich B, Stitelman D, Radu A, Li H, Zoltick P, Mitchell M. Increased epithelial stem cell migration in vivo in response to stem cell factor-1. Journal Of The American College Of Surgeons 2010, 211: s93. DOI: 10.1016/j.jamcollsurg.2010.06.246.
- Stitelman DH, Endo M, Bora A, Muvarak N, Zoltick PW, Flake AW, Brazelton TR. Robust In Vivo Transduction of Nervous System and Neural Stem Cells by Early Gestational Intra Amniotic Gene Transfer Using Lentiviral Vector. Molecular Therapy 2010, 18: 1615-1623. PMID: 20571539, PMCID: PMC2956924, DOI: 10.1038/mt.2010.125.
- Allukian M, Herdrich B, Bermudez D, Stitelman D, Chin B, Davey M, Gorman J, Gorman R, Liechty K. Restoration of Function Following in Utero Fetal MI Is Associated with Increased Cardiac Progenitor Cell Recruitment. Journal Of Surgical Research 2010, 158: 307. DOI: 10.1016/j.jss.2009.11.379.
- Endo M, Henriques-Coelho T, Zoltick PW, Stitelman DH, Peranteau WH, Radu A, Flake AW. The developmental stage determines the distribution and duration of gene expression after early intra-amniotic gene transfer using lentiviral vectors. Gene Therapy 2009, 17: 61-71. PMID: 19727133, DOI: 10.1038/gt.2009.115.
- Stitelman D, Bora A, Jeremy T, Merianos D, Flake A, Brazelton T. Efficient gene transfer to muscle satellite cells by in utero intravenous delivery of adeno-associated viral vector. Journal Of The American College Of Surgeons 2009, 209: s124. DOI: 10.1016/j.jamcollsurg.2009.06.309.
- Stitelman D, Masayuki E, Zoltick P, Brazelton T, Flake A. Gene transfer to progenitor cells of the central nervous system by early intraamniotic delivery of lentiviral vector. Journal Of The American College Of Surgeons 2008, 207: s103. DOI: 10.1016/j.jamcollsurg.2008.06.263.
- Keswani S, Parvadia J, Stitelman D, Kozin E, Radu A, Alaee D, Zoltick P, Crombleholme T. Mechanism of angiopoietin-1 mediated endothelial progenitor cell recruitment in wound healing. Journal Of The American College Of Surgeons 2004, 199: 60. DOI: 10.1016/j.jamcollsurg.2004.05.124.
- Tuma J, Connors W, Stitelman D, Richert C. On the Effect of Covalently Appended Quinolones on Termini of DNA Duplexes. Journal Of The American Chemical Society 2002, 124: 4236-4246. PMID: 11960452, DOI: 10.1021/ja0125117.
- Haas T, Stitelman D, Davis S, Apte S, Madri J. Egr-1 Mediates Extracellular Matrix-driven Transcription of Membrane Type 1 Matrix Metalloproteinase in Endothelium*. Journal Of Biological Chemistry 1999, 274: 22679-22685. PMID: 10428849, DOI: 10.1074/jbc.274.32.22679.
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- Yale New Haven Children's Hospital Specialty CentersYale New Haven Hospital - West Pavilion1 Park Street, Wing West Pavilion Ste 2nd FloorNew Haven, CT 06510
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