1
1 of 2
- Digestive DiseasesTemple Medical Center40 Temple Street, Ste 1ANew Haven, CT 06510
- Yale Medicine Digestive Diseases8 Devine StreetNorth Haven, CT 06473
Bubu Banini, MD, PhD
Hepatology, Obesity Medicine
Telehealth is available
Patient type treated
Adult
Accepting new patients
Yes
Referral required
From physicians only
Board Certified in
Obesity Medicine
Biography
Bubu Banini, MD, PhD, specializes in digestive diseases, treating various liver conditions, such as hepatitis A, B, and E, alcoholic cirrhosis, and nonalcoholic fatty liver disease (NAFLD).
As the Translational Research Director of the Metabolic Health and Weight Loss Program, Dr. Banini's research interests include NAFLD, decompensated cirrhosis and hepatic hydrothorax, liver cancer, portal hypertension and transient elastography, and the role of genes in alcoholic hepatitis.
Dr. Banini has received various awards, including the Young Scientist Travel Award, the Fellow Travel Awards for AASLD, DDW, ACG, and EASL, and the Early Investigator Career Enhancement Program Award.
Dr. Banini is an assistant professor of medicine at Yale School of Medicine.
Titles
- Assistant Professor of Medicine (Digestive Diseases)
- Translational Research Director of the Metabolic Health and Weight Loss Program, Digestive Diseases
Education & Training
- FellowshipVirginia Commonwealth University (2020)
- Clinical FellowshipVirginia Commonwealth University (2019)
- Research FellowshipVirginia Commonwealth University (2017)
- Post-doctoral Research FellowshipMayo Clinic (2015)
- Chief ResidencyMontefiore New Rochelle Hospital (Sound Shore Medical Center), Albert Einstein College of Medicine (2013)
- ResidencyMontefiore New Rochelle Hospital (Sound Shore Medical Center), Albert Einstein College of Medicine (2012)
- InternshipMontefiore Medical Center, Albert Einstein College of Medicine (2010)
- MDSidney Kimmel Medical College (Jefferson Medical College), Thomas Jefferson University (2009)
- PhDCollege of Graduate Studies, Thomas Jefferson University, Genetics and Molecular Biology (2009)
- Doctor of Medicine (M.D.)Sidney Kimmel Medical College (Jefferson Medical College), Thomas Jefferson University (2009)
- Doctor of Philosophy (Ph.D.)College of Graduate Studies, Thomas Jefferson University (2009)
- BASwarthmore College, Biology Major; Chemistry Minor (2002)
Additional Information
Honors & Recognitions
- Public Voices Fellow: Yale University (2023)
- Early Investigator Career Enhancement Program Award: National Institute on Alcohol Abuse and Alcoholism and the Office of Research on Women’s Health (2022)
- Best Poster Award : American College of Physicians (2022)
- AGA FORWARD Scholar: American Gastroenterology Association (2022)
- ACG Young Physician Leadership Program: American College of Gastroenterology (2021)
- Fellow Travel award for AASLD: Virginia Commonwealth University (2019)
- Fellow Travel Award for DDW: Virginia Commonwealth University (2019)
- Fellow Travel Award for ACG: Virginia Commonwealth University (2018)
- Young Scientist Travel Award: European Association for the Study of the Liver (2018)
- Fellow Travel Award: American College of Gastroenterology (2016)
Board Certifications
- AB of Obesity Medicine, Obesity Medicine (2021)
Professional Service
- American Association for the Study of Liver Disease (2023 - 2026): Membership and Mentorship Committee
- American Gastroenterological Association (2023 - 2024): AGA Nominating Committee
- Novo Nordisck (2023 - 2024): Board Member
- Research Society on Alcohol (2023): Abstract Reviewer
- American College of Gastroenterology (2023): Grant Reviewer
- Women's Health Education Champion (Digestive Diseases) (2023 - Present): Lead
- American Association for Study of the Liver (2023 - Present): Committee Member
- Clinical Liver Disease (2023 - Present): Editorial Board Member
- American College of Gastroenterology (2022 - 2023): Abstract Reviewer
- American Association for the Study of Liver Disease (2022 - 2023): Emerging Liver Scholar Program
Publications
- Barrios N, Riordan W, Garcia-Rivas V, Peltier M, Roberts W, Verplaetse T, Kohler R, Zhou H, Banini B, McKee S, Cosgrove K, Zakiniaeiz Y. Preclinical and clinical sex differences in the effects of alcohol on measures of brain dopamine: a systematic review. Biology Of Sex Differences 2025, 16: 24. PMID: 40200334, DOI: 10.1186/s13293-025-00706-7.
- Barrios N, Nartey N, Yue J, Riordan W, Kohler R, Verplaetse T, Roberts W, Carretta R, Banini B, Zhou H, Garcia-Rivas V, Blackford J, Zakiniaeiz Y. Sex-based Influences on White Matter Tract Integrity in Alcohol Use Disorder: a Systematic Review. Current Addiction Reports 2025, 12: 10. DOI: 10.1007/s40429-025-00624-z.
- Banini B, Chauhan S, Amatya A, Dashti F, Zahrawi K, Zahrawi F, Mehal W, McKee S. US mortality trends from alcohol‐associated hepatitis by sex, age, race, and ethnicity, 1999–2020. Alcohol Clinical And Experimental Research 2024, 49: 358-367. PMID: 39739407, DOI: 10.1111/acer.15515.
- Boateng S, Zahrawi F, Jalalzai M, Banini B. S1849 Are Patients With MASH Cirrhosis or Alcohol-Associated Cirrhosis More Likely to Develop Hepatic Hydrothorax? A National Transplant Database Analysis. The American Journal Of Gastroenterology 2024, 119: s1331-s1331. DOI: 10.14309/01.ajg.0001036764.22289.36.
- Fathma S, Boateng S, Amatya A, Ameyaw P, Banini B. The impact of MELD exception points for hydrothorax on posttransplant mortality: a propensity score-matched analysis. European Journal Of Gastroenterology & Hepatology 2024, 36: 1016-1021. PMID: 38829948, PMCID: PMC11230850, DOI: 10.1097/meg.0000000000002792.
- Boateng S, Ameyaw P, Annor E, Watt K, Banini B. 136 IMPACT OF PRE-TRANSPLANT MALIGNANCY ON INTESTINAL TRANSPLANT OUTCOMES: AN ANALYSIS OF THE UNITED NETWORK FOR ORGAN SHARING DATABASE. Gastroenterology 2024, 166: s-1778. DOI: 10.1016/s0016-5085(24)04561-x.
- Abboud Y, Ismail M, Khan H, Goyal R, Banini B. Tu1572 RACIAL DISPARITIES IN HEPATOCELLULAR CARCINOMA BASED ON TUMOR STAGE AT DIAGNOSIS: A NATIONWIDE POPULATION-BASED ANALYSIS USING THE UNITED STATES CANCER STATISTICS (USCS) DATABASE, 2001-2020. Gastroenterology 2024, 166: s-1735. DOI: 10.1016/s0016-5085(24)04454-8.
- Boateng S, Zahrawi F, Amatya A, Sanyal A, Banini B. Tu1606 EVOLVING BMI TRENDS IN LIVER TRANSPLANT RECIPIENTS: A 34-YEAR RETROSPECTIVE ANALYSIS (1988-2022). Gastroenterology 2024, 166: s-1359. DOI: 10.1016/s0016-5085(24)03577-7.
- Elliott E, Smith D, Lipscomb J, Banini B, Meurer L, Vanderford T, Johnson J, Jain D, Achhra A. Acute Hepatitis due to Primary Human Immunodeficiency Virus Infection. Open Forum Infectious Diseases 2024, 11: ofae170. PMID: 38585186, PMCID: PMC10996125, DOI: 10.1093/ofid/ofae170.
- Thevenot T, Raevens S, Aujayeb A, Banini B, Cadranel J, DuBrock H. Pulmonary complications of advanced chronic liver diseases: an updated review. Exploration Of Digestive Diseases 2024, 3: 301-325. DOI: 10.37349/edd.2024.00053.
- Lam R, Banini B, Do A, Lim J. Chapter 6 Clinical diagnosis and evaluation pathway. 2024, 77-100. DOI: 10.1016/b978-0-323-99649-5.00003-0.
- White M, Alvarado M, Joldoshova A, Zhang X, Banini B. S3757 A Case of Late-Onset Hepatic Sinusoidal Obstructive Syndrome/Veno-Occlusive Disease One Year Post Transplant. The American Journal Of Gastroenterology 2023, 118: s2423-s2423. DOI: 10.14309/01.ajg.0000964668.39868.c7.
- Ismail M, Asotibe J, Akuna E, Banini B. S1453 Regional Variation in Baseline Characteristics and Clinical Outcomes of Decompensated Cirrhosis With Hepatic Hydrothorax. The American Journal Of Gastroenterology 2023, 118: s1109-s1109. DOI: 10.14309/01.ajg.0000955452.92758.00.
- Do A, Ilagan-Ying Y, Deng Y, Banini B, Lim J, Mehal W. S1581 Assessing the Effectiveness of Incorporating Weight Management Treatments Into a Fatty Liver Disease Program. The American Journal Of Gastroenterology 2023, 118: s1193-s1194. DOI: 10.14309/01.ajg.0000955964.73046.7b.
- Ilagan-Ying Y, Banini B, Do A, Lam R, Lim J. Screening, Diagnosis, and Staging of Non-Alcoholic Fatty Liver Disease (NAFLD): Application of Society Guidelines to Clinical Practice. Current Gastroenterology Reports 2023, 25: 213-224. PMID: 37768417, DOI: 10.1007/s11894-023-00883-8.
- Chen G, Banini B, Do A, Gunderson C, Zaman S, Lim J. Exercise Does Not Independently Improve Histological Outcomes in Biopsy-Proven Non-Alcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis. Genes 2023, 14: 1811. PMID: 37761951, PMCID: PMC10531443, DOI: 10.3390/genes14091811.
- Agyapong G, Dashti F, Banini B. Nonalcoholic liver disease: Epidemiology, risk factors, natural history, and management strategies. Annals Of The New York Academy Of Sciences 2023, 1526: 16-29. PMID: 37400359, PMCID: PMC10524684, DOI: 10.1111/nyas.15012.
- Zahrawi F, Fathma S, Mehal W, Banini B. Pharmacologic Management of Obesity after Liver Transplantation: A Critical Review. Annals Of Gastroenterology And Digestive Disorders 2023, 6: 17-25. PMID: 38098758, PMCID: PMC10719957.
- New uses for an old remedy: Digoxin as a potential treatment for steatohepatitis and other disordersJamshed F, Dashti F, Ouyang X, Mehal W, Banini B. New uses for an old remedy: Digoxin as a potential treatment for steatohepatitis and other disorders. World Journal Of Gastroenterology 2023, 29: 1824-1837. PMID: 37032732, PMCID: PMC10080697, DOI: 10.3748/wjg.v29.i12.1824.
- Chen G, Banini B, Do A, Lim J. The Independent Effect of Exercise on Biopsy-Proven Non-Alcoholic Fatty Liver Disease: A Systematic Review. Clinical And Molecular Hepatology 2022, 29: s319-s332. PMID: 36517000, PMCID: PMC10029942, DOI: 10.3350/cmh.2022.0366.
- Dashti F, Jamshed F, Ouyang X, Mehal W, Banini B. Digoxin as an emerging therapy in noncardiac diseases. Trends In Pharmacological Sciences 2022, 44: 199-203. PMID: 36396496, DOI: 10.1016/j.tips.2022.10.002.
- Banini BA, Mehta R, Santhekadur PK. Editorial: Recent advances in the understanding of hepatocellular carcinogenesis. Frontiers In Oncology 2022, 12: 963998. PMID: 35936725, PMCID: PMC9350505, DOI: 10.3389/fonc.2022.963998.
- Asotibe JC, Banini BA. Hepatic Hydrothorax: An Independent Predictor of Mortality in Cirrhosis? Is the MELD-Na Score Worth Its Salt? Digestive Diseases And Sciences 2022, 67: 4609-4611. PMID: 35534743, DOI: 10.1007/s10620-022-07523-7.
- Banini BA, Patel S, Yu JW, Kang L, Bailey C, Strife BJ, Siddiqui MS, Patel V, Matherly SC, Lee H, Lewis S, Cherian R, Stravitz RT, Luketic V, Sanyal AJ, Sterling RK. Derivation and Validation of a Model to Predict Clinically Significant Portal Hypertension Using Transient Elastography and FIB-4. Journal Of Clinical Gastroenterology 2022, 57: 189-197. PMID: 34999644, PMCID: PMC9271129, DOI: 10.1097/mcg.0000000000001664.
- Beaudoin JJ, Liang T, Tang Q, Banini BA, Shah VH, Sanyal AJ, Chalasani NP, Gawrieh S. Role of candidate gene variants in modulating the risk and severity of alcoholic hepatitis. Alcohol Clinical And Experimental Research 2021, 45: 709-719. PMID: 33616244, PMCID: PMC8076096, DOI: 10.1111/acer.14581.
- Banini BA, Kumar DP, Cazanave S, Seneshaw M, Mirshahi F, Santhekadur PK, Wang L, Guan HP, Oseini AM, Alonso C, Bedossa P, Koduru SV, Min H, Sanyal AJ. Identification of a Metabolic, Transcriptomic, and Molecular Signature of Patatin‐Like Phospholipase Domain Containing 3–Mediated Acceleration of Steatohepatitis. Hepatology 2021, 73: 1290-1306. PMID: 33131062, PMCID: PMC8046714, DOI: 10.1002/hep.31609.
- Banini BA, Alwatari Y, Ogden N, Gershman E, Shah RD, Strife BJ, Shojaee S, Sterling RK. Reply:. Hepatology 2021, 73: 1237-1238. PMID: 32767857, DOI: 10.1002/hep.31512.
- Banini BA, Sanyal AJ. NAFLD-related HCC. Advances In Cancer Research 2021, 149: 143-169. PMID: 33579423, DOI: 10.1016/bs.acr.2020.11.001.
- Banini BA, Alwatari Y, Stovall M, Ogden N, Gershman E, Shah RD, Strife BJ, Shojaee S, Sterling RK. Multidisciplinary Management of Hepatic Hydrothorax in 2020: An Evidence‐Based Review and Guidance. Hepatology 2020, 72: 1851-1863. PMID: 32585037, DOI: 10.1002/hep.31434.
- Kim TH, Banini BA, Asumda FZ, Campbell NA, Hu C, Moser CD, Shire AM, Han S, Ma C, Krishnan A, Mounajjed T, White TA, Gores GJ, LeBrasseur NK, Charlton MR, Roberts LR. Knockout of sulfatase 2 is associated with decreased steatohepatitis and fibrosis in a mouse model of nonalcoholic fatty liver disease. AJP Gastrointestinal And Liver Physiology 2020, 319: g333-g344. PMID: 32683952, PMCID: PMC7509257, DOI: 10.1152/ajpgi.00150.2019.
- Carr RM, Romecin Duran PA, Tolosa EJ, Ma C, Oseini AM, Moser CD, Banini BA, Huang J, Asumda F, Dhanasekaran R, Graham RP, Toruner MD, Safgren SL, Almada LL, Wang S, Patnaik MM, Roberts LR, Fernandez-Zapico ME. The extracellular sulfatase SULF2 promotes liver tumorigenesis by stimulating assembly of a promoter-looping GLI1-STAT3 transcriptional complex. Journal Of Biological Chemistry 2020, 295: 2698-2712. PMID: 31988246, PMCID: PMC7049957, DOI: 10.1074/jbc.ra119.011146.
- Banini BA, Cazanave SC, Yates KP, Asgharpour A, Vincent R, Mirshahi F, Le P, Contos MJ, Tonascia J, Chalasani NP, Kowdley KV, McCullough AJ, Behling CA, Schwimmer JB, Lavine JE, Sanyal AJ. Haptoglobin 2 Allele is Associated With Histologic Response to Vitamin E in Subjects With Nonalcoholic Steatohepatitis. Journal Of Clinical Gastroenterology 2019, 53: 750-758. PMID: 30586008, PMCID: PMC6588507, DOI: 10.1097/mcg.0000000000001142.
- Banini BA, Sanyal AJ. The use of cell free DNA in the diagnosis of HCC. Hepatoma Research 2019, 2019: 34. PMID: 31673629, PMCID: PMC6822275, DOI: 10.20517/2394-5079.2019.30.
- Lee HM, Banini BA. Updates on Chronic HBV: Current Challenges and Future Goals. Current Treatment Options In Gastroenterology 2019, 17: 271-291. PMID: 31077059, DOI: 10.1007/s11938-019-00236-3.
- Banini B, Sanyal A. Vitamin E in Nonalcoholic Fatty Liver Disease. Nutrition And Health 2019, 311-323. DOI: 10.1007/978-3-030-05315-4_23.
- Banini B, Sanyal A. Coagulopathy: Pathophysiology, Evaluation, and Treatment. 2018, 173-193. DOI: 10.1007/978-3-319-64298-7_15.
- Cazanave S, Podtelezhnikov A, Jensen K, Seneshaw M, Kumar DP, Min HK, Santhekadur PK, Banini B, Mauro AG, M. Oseini A, Vincent R, Tanis KQ, Webber AL, Wang L, Bedossa P, Mirshahi F, Sanyal AJ. The Transcriptomic Signature Of Disease Development And Progression Of Nonalcoholic Fatty Liver Disease. Scientific Reports 2017, 7: 17193. PMID: 29222421, PMCID: PMC5722878, DOI: 10.1038/s41598-017-17370-6.
- Banini BA, Sanyal AJ. Corrigendum: Treatment of NASH: What Helps Beyond Weight Loss? The American Journal Of Gastroenterology 2017, 112: 1352-1352. PMID: 28631731, DOI: 10.1038/ajg.2017.187.
- Banini BA, Sanyal AJ. Current and future pharmacologic treatment of nonalcoholic steatohepatitis. Current Opinion In Gastroenterology 2017, 33: 134-141. PMID: 28346237, PMCID: PMC5491795, DOI: 10.1097/mog.0000000000000356.
- Banini BA, Sanyal AJ. Treatment of NASH: What Helps Beyond Weight Loss? The American Journal Of Gastroenterology 2017, 112: 821. PMID: 28397875, DOI: 10.1038/ajg.2017.83.
- Chen G, Nakamura I, Dhanasekaran R, Iguchi E, Tolosa EJ, Romecin PA, Vera RE, Almada LL, Miamen AG, Chaiteerakij R, Zhou M, Asiedu MK, Moser CD, Han S, Hu C, Banini BA, Oseini AM, Chen Y, Fang Y, Yang D, Shaleh HM, Wang S, Wu D, Song T, Lee JS, Thorgeirsson SS, Chevet E, Shah VH, Fernandez-Zapico ME, Roberts LR. Transcriptional Induction of Periostin by a Sulfatase 2–TGFβ1–SMAD Signaling Axis Mediates Tumor Angiogenesis in Hepatocellular Carcinoma. Cancer Research 2017, 77: 632-645. PMID: 27872089, PMCID: PMC5429157, DOI: 10.1158/0008-5472.can-15-2556.
- Asgharpour A, Cazanave SC, Pacana T, Seneshaw M, Vincent R, Banini BA, Kumar DP, Daita K, Min HK, Mirshahi F, Bedossa P, Sun X, Hoshida Y, Koduru SV, Contaifer D, Warncke UO, Wijesinghe DS, Sanyal AJ. A diet-induced animal model of non-alcoholic fatty liver disease and hepatocellular cancer. Journal Of Hepatology 2016, 65: 579-588. PMID: 27261415, PMCID: PMC5012902, DOI: 10.1016/j.jhep.2016.05.005.
- Mota M, Banini BA, Cazanave SC, Sanyal AJ. Molecular mechanisms of lipotoxicity and glucotoxicity in nonalcoholic fatty liver disease. Metabolism 2016, 65: 1049-1061. PMID: 26997538, PMCID: PMC4931958, DOI: 10.1016/j.metabol.2016.02.014.
- Banini BA, Sanyal AJ. Nonalcoholic Fatty Liver Disease: Epidemiology, Pathogenesis, Natural History, Diagnosis, and Current Treatment Options. Clinical Medicine Insights Therapeutics 2016, 8: cmt.s18885. PMID: 28670148, PMCID: PMC5491796, DOI: 10.4137/cmt.s18885.
- Banini B, Roberts L. Hepatocellular Carcinoma. 2015, 207-218. DOI: 10.1007/978-3-319-13614-1_22.
- Hepatocellular carcinoma. In Complications of Cirrhosis: Evaluation and Management.Banini BA and Roberts LR. Hepatocellular carcinoma. In Complications of Cirrhosis: Evaluation and Management. Keaveny A and Cardenas A, Editors. Springer 2015.
- Nakamura I, Zakharia K, Banini BA, Mikhail DS, Kim TH, Yang JD, Moser CD, Shaleh HM, Thornburgh SR, Walters I, Roberts LR. Brivanib Attenuates Hepatic Fibrosis In Vivo and Stellate Cell Activation In Vitro by Inhibition of FGF, VEGF and PDGF Signaling. PLOS ONE 2014, 9: e92273. PMID: 24710173, PMCID: PMC3977817, DOI: 10.1371/journal.pone.0092273.
- Keller MA, Addya S, Vadigepalli R, Banini B, Delgrosso K, Huang H, Surrey S. Transcriptional regulatory network analysis of developing human erythroid progenitors reveals patterns of coregulation and potential transcriptional regulators. Physiological Genomics 2006, 28: 114-128. PMID: 16940433, DOI: 10.1152/physiolgenomics.00055.2006.
- Keller M, Addya S, Vadigepalli R, Ponte C, Banini B, Delgrosso K, Surrey S. Transcriptome Analysis of Human Hematopoietic Progenitor Cells during In Vitro Erythroid Differentiation. Blood 2005, 106: 1750. DOI: 10.1182/blood.v106.11.1750.1750.
Departments and Programs
Locations
1
1 of 2
- Digestive DiseasesTemple Medical Center40 Temple Street, Ste 1ANew Haven, CT 06510
- Yale Medicine Digestive Diseases8 Devine StreetNorth Haven, CT 06473
Biography
Bubu Banini, MD, PhD, specializes in digestive diseases, treating various liver conditions, such as hepatitis A, B, and E, alcoholic cirrhosis, and nonalcoholic fatty liver disease (NAFLD).
As the Translational Research Director of the Metabolic Health and Weight Loss Program, Dr. Banini's research interests include NAFLD, decompensated cirrhosis and hepatic hydrothorax, liver cancer, portal hypertension and transient elastography, and the role of genes in alcoholic hepatitis.
Dr. Banini has received various awards, including the Young Scientist Travel Award, the Fellow Travel Awards for AASLD, DDW, ACG, and EASL, and the Early Investigator Career Enhancement Program Award.
Dr. Banini is an assistant professor of medicine at Yale School of Medicine.
Titles
- Assistant Professor of Medicine (Digestive Diseases)
- Translational Research Director of the Metabolic Health and Weight Loss Program, Digestive Diseases
Education & Training
- FellowshipVirginia Commonwealth University (2020)
- Clinical FellowshipVirginia Commonwealth University (2019)
- Research FellowshipVirginia Commonwealth University (2017)
- Post-doctoral Research FellowshipMayo Clinic (2015)
- Chief ResidencyMontefiore New Rochelle Hospital (Sound Shore Medical Center), Albert Einstein College of Medicine (2013)
- ResidencyMontefiore New Rochelle Hospital (Sound Shore Medical Center), Albert Einstein College of Medicine (2012)
- InternshipMontefiore Medical Center, Albert Einstein College of Medicine (2010)
- MDSidney Kimmel Medical College (Jefferson Medical College), Thomas Jefferson University (2009)
- PhDCollege of Graduate Studies, Thomas Jefferson University, Genetics and Molecular Biology (2009)
- Doctor of Medicine (M.D.)Sidney Kimmel Medical College (Jefferson Medical College), Thomas Jefferson University (2009)
- Doctor of Philosophy (Ph.D.)College of Graduate Studies, Thomas Jefferson University (2009)
- BASwarthmore College, Biology Major; Chemistry Minor (2002)
Additional Information
Honors & Recognitions
- Public Voices Fellow: Yale University (2023)
- Early Investigator Career Enhancement Program Award: National Institute on Alcohol Abuse and Alcoholism and the Office of Research on Women’s Health (2022)
- Best Poster Award : American College of Physicians (2022)
- AGA FORWARD Scholar: American Gastroenterology Association (2022)
- ACG Young Physician Leadership Program: American College of Gastroenterology (2021)
- Fellow Travel award for AASLD: Virginia Commonwealth University (2019)
- Fellow Travel Award for DDW: Virginia Commonwealth University (2019)
- Fellow Travel Award for ACG: Virginia Commonwealth University (2018)
- Young Scientist Travel Award: European Association for the Study of the Liver (2018)
- Fellow Travel Award: American College of Gastroenterology (2016)
Board Certifications
- AB of Obesity Medicine, Obesity Medicine (2021)
Professional Service
- American Association for the Study of Liver Disease (2023 - 2026): Membership and Mentorship Committee
- American Gastroenterological Association (2023 - 2024): AGA Nominating Committee
- Novo Nordisck (2023 - 2024): Board Member
- Research Society on Alcohol (2023): Abstract Reviewer
- American College of Gastroenterology (2023): Grant Reviewer
- Women's Health Education Champion (Digestive Diseases) (2023 - Present): Lead
- American Association for Study of the Liver (2023 - Present): Committee Member
- Clinical Liver Disease (2023 - Present): Editorial Board Member
- American College of Gastroenterology (2022 - 2023): Abstract Reviewer
- American Association for the Study of Liver Disease (2022 - 2023): Emerging Liver Scholar Program
Publications
- Barrios N, Riordan W, Garcia-Rivas V, Peltier M, Roberts W, Verplaetse T, Kohler R, Zhou H, Banini B, McKee S, Cosgrove K, Zakiniaeiz Y. Preclinical and clinical sex differences in the effects of alcohol on measures of brain dopamine: a systematic review. Biology Of Sex Differences 2025, 16: 24. PMID: 40200334, DOI: 10.1186/s13293-025-00706-7.
- Barrios N, Nartey N, Yue J, Riordan W, Kohler R, Verplaetse T, Roberts W, Carretta R, Banini B, Zhou H, Garcia-Rivas V, Blackford J, Zakiniaeiz Y. Sex-based Influences on White Matter Tract Integrity in Alcohol Use Disorder: a Systematic Review. Current Addiction Reports 2025, 12: 10. DOI: 10.1007/s40429-025-00624-z.
- Banini B, Chauhan S, Amatya A, Dashti F, Zahrawi K, Zahrawi F, Mehal W, McKee S. US mortality trends from alcohol‐associated hepatitis by sex, age, race, and ethnicity, 1999–2020. Alcohol Clinical And Experimental Research 2024, 49: 358-367. PMID: 39739407, DOI: 10.1111/acer.15515.
- Boateng S, Zahrawi F, Jalalzai M, Banini B. S1849 Are Patients With MASH Cirrhosis or Alcohol-Associated Cirrhosis More Likely to Develop Hepatic Hydrothorax? A National Transplant Database Analysis. The American Journal Of Gastroenterology 2024, 119: s1331-s1331. DOI: 10.14309/01.ajg.0001036764.22289.36.
- Fathma S, Boateng S, Amatya A, Ameyaw P, Banini B. The impact of MELD exception points for hydrothorax on posttransplant mortality: a propensity score-matched analysis. European Journal Of Gastroenterology & Hepatology 2024, 36: 1016-1021. PMID: 38829948, PMCID: PMC11230850, DOI: 10.1097/meg.0000000000002792.
- Boateng S, Ameyaw P, Annor E, Watt K, Banini B. 136 IMPACT OF PRE-TRANSPLANT MALIGNANCY ON INTESTINAL TRANSPLANT OUTCOMES: AN ANALYSIS OF THE UNITED NETWORK FOR ORGAN SHARING DATABASE. Gastroenterology 2024, 166: s-1778. DOI: 10.1016/s0016-5085(24)04561-x.
- Abboud Y, Ismail M, Khan H, Goyal R, Banini B. Tu1572 RACIAL DISPARITIES IN HEPATOCELLULAR CARCINOMA BASED ON TUMOR STAGE AT DIAGNOSIS: A NATIONWIDE POPULATION-BASED ANALYSIS USING THE UNITED STATES CANCER STATISTICS (USCS) DATABASE, 2001-2020. Gastroenterology 2024, 166: s-1735. DOI: 10.1016/s0016-5085(24)04454-8.
- Boateng S, Zahrawi F, Amatya A, Sanyal A, Banini B. Tu1606 EVOLVING BMI TRENDS IN LIVER TRANSPLANT RECIPIENTS: A 34-YEAR RETROSPECTIVE ANALYSIS (1988-2022). Gastroenterology 2024, 166: s-1359. DOI: 10.1016/s0016-5085(24)03577-7.
- Elliott E, Smith D, Lipscomb J, Banini B, Meurer L, Vanderford T, Johnson J, Jain D, Achhra A. Acute Hepatitis due to Primary Human Immunodeficiency Virus Infection. Open Forum Infectious Diseases 2024, 11: ofae170. PMID: 38585186, PMCID: PMC10996125, DOI: 10.1093/ofid/ofae170.
- Thevenot T, Raevens S, Aujayeb A, Banini B, Cadranel J, DuBrock H. Pulmonary complications of advanced chronic liver diseases: an updated review. Exploration Of Digestive Diseases 2024, 3: 301-325. DOI: 10.37349/edd.2024.00053.
- Lam R, Banini B, Do A, Lim J. Chapter 6 Clinical diagnosis and evaluation pathway. 2024, 77-100. DOI: 10.1016/b978-0-323-99649-5.00003-0.
- White M, Alvarado M, Joldoshova A, Zhang X, Banini B. S3757 A Case of Late-Onset Hepatic Sinusoidal Obstructive Syndrome/Veno-Occlusive Disease One Year Post Transplant. The American Journal Of Gastroenterology 2023, 118: s2423-s2423. DOI: 10.14309/01.ajg.0000964668.39868.c7.
- Ismail M, Asotibe J, Akuna E, Banini B. S1453 Regional Variation in Baseline Characteristics and Clinical Outcomes of Decompensated Cirrhosis With Hepatic Hydrothorax. The American Journal Of Gastroenterology 2023, 118: s1109-s1109. DOI: 10.14309/01.ajg.0000955452.92758.00.
- Do A, Ilagan-Ying Y, Deng Y, Banini B, Lim J, Mehal W. S1581 Assessing the Effectiveness of Incorporating Weight Management Treatments Into a Fatty Liver Disease Program. The American Journal Of Gastroenterology 2023, 118: s1193-s1194. DOI: 10.14309/01.ajg.0000955964.73046.7b.
- Ilagan-Ying Y, Banini B, Do A, Lam R, Lim J. Screening, Diagnosis, and Staging of Non-Alcoholic Fatty Liver Disease (NAFLD): Application of Society Guidelines to Clinical Practice. Current Gastroenterology Reports 2023, 25: 213-224. PMID: 37768417, DOI: 10.1007/s11894-023-00883-8.
- Chen G, Banini B, Do A, Gunderson C, Zaman S, Lim J. Exercise Does Not Independently Improve Histological Outcomes in Biopsy-Proven Non-Alcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis. Genes 2023, 14: 1811. PMID: 37761951, PMCID: PMC10531443, DOI: 10.3390/genes14091811.
- Agyapong G, Dashti F, Banini B. Nonalcoholic liver disease: Epidemiology, risk factors, natural history, and management strategies. Annals Of The New York Academy Of Sciences 2023, 1526: 16-29. PMID: 37400359, PMCID: PMC10524684, DOI: 10.1111/nyas.15012.
- Zahrawi F, Fathma S, Mehal W, Banini B. Pharmacologic Management of Obesity after Liver Transplantation: A Critical Review. Annals Of Gastroenterology And Digestive Disorders 2023, 6: 17-25. PMID: 38098758, PMCID: PMC10719957.
- New uses for an old remedy: Digoxin as a potential treatment for steatohepatitis and other disordersJamshed F, Dashti F, Ouyang X, Mehal W, Banini B. New uses for an old remedy: Digoxin as a potential treatment for steatohepatitis and other disorders. World Journal Of Gastroenterology 2023, 29: 1824-1837. PMID: 37032732, PMCID: PMC10080697, DOI: 10.3748/wjg.v29.i12.1824.
- Chen G, Banini B, Do A, Lim J. The Independent Effect of Exercise on Biopsy-Proven Non-Alcoholic Fatty Liver Disease: A Systematic Review. Clinical And Molecular Hepatology 2022, 29: s319-s332. PMID: 36517000, PMCID: PMC10029942, DOI: 10.3350/cmh.2022.0366.
- Dashti F, Jamshed F, Ouyang X, Mehal W, Banini B. Digoxin as an emerging therapy in noncardiac diseases. Trends In Pharmacological Sciences 2022, 44: 199-203. PMID: 36396496, DOI: 10.1016/j.tips.2022.10.002.
- Banini BA, Mehta R, Santhekadur PK. Editorial: Recent advances in the understanding of hepatocellular carcinogenesis. Frontiers In Oncology 2022, 12: 963998. PMID: 35936725, PMCID: PMC9350505, DOI: 10.3389/fonc.2022.963998.
- Asotibe JC, Banini BA. Hepatic Hydrothorax: An Independent Predictor of Mortality in Cirrhosis? Is the MELD-Na Score Worth Its Salt? Digestive Diseases And Sciences 2022, 67: 4609-4611. PMID: 35534743, DOI: 10.1007/s10620-022-07523-7.
- Banini BA, Patel S, Yu JW, Kang L, Bailey C, Strife BJ, Siddiqui MS, Patel V, Matherly SC, Lee H, Lewis S, Cherian R, Stravitz RT, Luketic V, Sanyal AJ, Sterling RK. Derivation and Validation of a Model to Predict Clinically Significant Portal Hypertension Using Transient Elastography and FIB-4. Journal Of Clinical Gastroenterology 2022, 57: 189-197. PMID: 34999644, PMCID: PMC9271129, DOI: 10.1097/mcg.0000000000001664.
- Beaudoin JJ, Liang T, Tang Q, Banini BA, Shah VH, Sanyal AJ, Chalasani NP, Gawrieh S. Role of candidate gene variants in modulating the risk and severity of alcoholic hepatitis. Alcohol Clinical And Experimental Research 2021, 45: 709-719. PMID: 33616244, PMCID: PMC8076096, DOI: 10.1111/acer.14581.
- Banini BA, Kumar DP, Cazanave S, Seneshaw M, Mirshahi F, Santhekadur PK, Wang L, Guan HP, Oseini AM, Alonso C, Bedossa P, Koduru SV, Min H, Sanyal AJ. Identification of a Metabolic, Transcriptomic, and Molecular Signature of Patatin‐Like Phospholipase Domain Containing 3–Mediated Acceleration of Steatohepatitis. Hepatology 2021, 73: 1290-1306. PMID: 33131062, PMCID: PMC8046714, DOI: 10.1002/hep.31609.
- Banini BA, Alwatari Y, Ogden N, Gershman E, Shah RD, Strife BJ, Shojaee S, Sterling RK. Reply:. Hepatology 2021, 73: 1237-1238. PMID: 32767857, DOI: 10.1002/hep.31512.
- Banini BA, Sanyal AJ. NAFLD-related HCC. Advances In Cancer Research 2021, 149: 143-169. PMID: 33579423, DOI: 10.1016/bs.acr.2020.11.001.
- Banini BA, Alwatari Y, Stovall M, Ogden N, Gershman E, Shah RD, Strife BJ, Shojaee S, Sterling RK. Multidisciplinary Management of Hepatic Hydrothorax in 2020: An Evidence‐Based Review and Guidance. Hepatology 2020, 72: 1851-1863. PMID: 32585037, DOI: 10.1002/hep.31434.
- Kim TH, Banini BA, Asumda FZ, Campbell NA, Hu C, Moser CD, Shire AM, Han S, Ma C, Krishnan A, Mounajjed T, White TA, Gores GJ, LeBrasseur NK, Charlton MR, Roberts LR. Knockout of sulfatase 2 is associated with decreased steatohepatitis and fibrosis in a mouse model of nonalcoholic fatty liver disease. AJP Gastrointestinal And Liver Physiology 2020, 319: g333-g344. PMID: 32683952, PMCID: PMC7509257, DOI: 10.1152/ajpgi.00150.2019.
- Carr RM, Romecin Duran PA, Tolosa EJ, Ma C, Oseini AM, Moser CD, Banini BA, Huang J, Asumda F, Dhanasekaran R, Graham RP, Toruner MD, Safgren SL, Almada LL, Wang S, Patnaik MM, Roberts LR, Fernandez-Zapico ME. The extracellular sulfatase SULF2 promotes liver tumorigenesis by stimulating assembly of a promoter-looping GLI1-STAT3 transcriptional complex. Journal Of Biological Chemistry 2020, 295: 2698-2712. PMID: 31988246, PMCID: PMC7049957, DOI: 10.1074/jbc.ra119.011146.
- Banini BA, Cazanave SC, Yates KP, Asgharpour A, Vincent R, Mirshahi F, Le P, Contos MJ, Tonascia J, Chalasani NP, Kowdley KV, McCullough AJ, Behling CA, Schwimmer JB, Lavine JE, Sanyal AJ. Haptoglobin 2 Allele is Associated With Histologic Response to Vitamin E in Subjects With Nonalcoholic Steatohepatitis. Journal Of Clinical Gastroenterology 2019, 53: 750-758. PMID: 30586008, PMCID: PMC6588507, DOI: 10.1097/mcg.0000000000001142.
- Banini BA, Sanyal AJ. The use of cell free DNA in the diagnosis of HCC. Hepatoma Research 2019, 2019: 34. PMID: 31673629, PMCID: PMC6822275, DOI: 10.20517/2394-5079.2019.30.
- Lee HM, Banini BA. Updates on Chronic HBV: Current Challenges and Future Goals. Current Treatment Options In Gastroenterology 2019, 17: 271-291. PMID: 31077059, DOI: 10.1007/s11938-019-00236-3.
- Banini B, Sanyal A. Vitamin E in Nonalcoholic Fatty Liver Disease. Nutrition And Health 2019, 311-323. DOI: 10.1007/978-3-030-05315-4_23.
- Banini B, Sanyal A. Coagulopathy: Pathophysiology, Evaluation, and Treatment. 2018, 173-193. DOI: 10.1007/978-3-319-64298-7_15.
- Cazanave S, Podtelezhnikov A, Jensen K, Seneshaw M, Kumar DP, Min HK, Santhekadur PK, Banini B, Mauro AG, M. Oseini A, Vincent R, Tanis KQ, Webber AL, Wang L, Bedossa P, Mirshahi F, Sanyal AJ. The Transcriptomic Signature Of Disease Development And Progression Of Nonalcoholic Fatty Liver Disease. Scientific Reports 2017, 7: 17193. PMID: 29222421, PMCID: PMC5722878, DOI: 10.1038/s41598-017-17370-6.
- Banini BA, Sanyal AJ. Corrigendum: Treatment of NASH: What Helps Beyond Weight Loss? The American Journal Of Gastroenterology 2017, 112: 1352-1352. PMID: 28631731, DOI: 10.1038/ajg.2017.187.
- Banini BA, Sanyal AJ. Current and future pharmacologic treatment of nonalcoholic steatohepatitis. Current Opinion In Gastroenterology 2017, 33: 134-141. PMID: 28346237, PMCID: PMC5491795, DOI: 10.1097/mog.0000000000000356.
- Banini BA, Sanyal AJ. Treatment of NASH: What Helps Beyond Weight Loss? The American Journal Of Gastroenterology 2017, 112: 821. PMID: 28397875, DOI: 10.1038/ajg.2017.83.
- Chen G, Nakamura I, Dhanasekaran R, Iguchi E, Tolosa EJ, Romecin PA, Vera RE, Almada LL, Miamen AG, Chaiteerakij R, Zhou M, Asiedu MK, Moser CD, Han S, Hu C, Banini BA, Oseini AM, Chen Y, Fang Y, Yang D, Shaleh HM, Wang S, Wu D, Song T, Lee JS, Thorgeirsson SS, Chevet E, Shah VH, Fernandez-Zapico ME, Roberts LR. Transcriptional Induction of Periostin by a Sulfatase 2–TGFβ1–SMAD Signaling Axis Mediates Tumor Angiogenesis in Hepatocellular Carcinoma. Cancer Research 2017, 77: 632-645. PMID: 27872089, PMCID: PMC5429157, DOI: 10.1158/0008-5472.can-15-2556.
- Asgharpour A, Cazanave SC, Pacana T, Seneshaw M, Vincent R, Banini BA, Kumar DP, Daita K, Min HK, Mirshahi F, Bedossa P, Sun X, Hoshida Y, Koduru SV, Contaifer D, Warncke UO, Wijesinghe DS, Sanyal AJ. A diet-induced animal model of non-alcoholic fatty liver disease and hepatocellular cancer. Journal Of Hepatology 2016, 65: 579-588. PMID: 27261415, PMCID: PMC5012902, DOI: 10.1016/j.jhep.2016.05.005.
- Mota M, Banini BA, Cazanave SC, Sanyal AJ. Molecular mechanisms of lipotoxicity and glucotoxicity in nonalcoholic fatty liver disease. Metabolism 2016, 65: 1049-1061. PMID: 26997538, PMCID: PMC4931958, DOI: 10.1016/j.metabol.2016.02.014.
- Banini BA, Sanyal AJ. Nonalcoholic Fatty Liver Disease: Epidemiology, Pathogenesis, Natural History, Diagnosis, and Current Treatment Options. Clinical Medicine Insights Therapeutics 2016, 8: cmt.s18885. PMID: 28670148, PMCID: PMC5491796, DOI: 10.4137/cmt.s18885.
- Banini B, Roberts L. Hepatocellular Carcinoma. 2015, 207-218. DOI: 10.1007/978-3-319-13614-1_22.
- Hepatocellular carcinoma. In Complications of Cirrhosis: Evaluation and Management.Banini BA and Roberts LR. Hepatocellular carcinoma. In Complications of Cirrhosis: Evaluation and Management. Keaveny A and Cardenas A, Editors. Springer 2015.
- Nakamura I, Zakharia K, Banini BA, Mikhail DS, Kim TH, Yang JD, Moser CD, Shaleh HM, Thornburgh SR, Walters I, Roberts LR. Brivanib Attenuates Hepatic Fibrosis In Vivo and Stellate Cell Activation In Vitro by Inhibition of FGF, VEGF and PDGF Signaling. PLOS ONE 2014, 9: e92273. PMID: 24710173, PMCID: PMC3977817, DOI: 10.1371/journal.pone.0092273.
- Keller MA, Addya S, Vadigepalli R, Banini B, Delgrosso K, Huang H, Surrey S. Transcriptional regulatory network analysis of developing human erythroid progenitors reveals patterns of coregulation and potential transcriptional regulators. Physiological Genomics 2006, 28: 114-128. PMID: 16940433, DOI: 10.1152/physiolgenomics.00055.2006.
- Keller M, Addya S, Vadigepalli R, Ponte C, Banini B, Delgrosso K, Surrey S. Transcriptome Analysis of Human Hematopoietic Progenitor Cells during In Vitro Erythroid Differentiation. Blood 2005, 106: 1750. DOI: 10.1182/blood.v106.11.1750.1750.
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- Digestive DiseasesTemple Medical Center40 Temple Street, Ste 1ANew Haven, CT 06510
- Yale Medicine Digestive Diseases8 Devine StreetNorth Haven, CT 06473
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1 of 2
- Digestive DiseasesTemple Medical Center40 Temple Street, Ste 1ANew Haven, CT 06510
- Yale Medicine Digestive Diseases8 Devine StreetNorth Haven, CT 06473