Yale Therapeutic Radiology
Lawrence + Memorial Cancer Center
230 Waterford Parkway South
Waterford, CT 06385
- Yale Therapeutic RadiologyLawrence + Memorial Cancer Center230 Waterford Parkway SouthWaterford, CT 06385
Abhijit Patel, MD, PhD
Therapeutic Radiology
Telehealth is available
Patient type treated
Adult
Accepting new patients
Yes
Referral required
From patients or physicians
Board Certified in
Radiation Oncology
Titles
- Associate Professor of Therapeutic Radiology
Education & Training
- Postdoctoral ResearchHHMI, Massachusetts General Hospital (2008)
- ResidencyHarvard Radiation Oncology (2008)
- InternshipMemorial Sloan-Kettering Cancer Center (2004)
- MDYale University School of Medicine (2003)
- PhDYale University Graduate School, Molecular Biophysics and Biochemistry (2002)
- MSYale College, Chemistry (1995)
- BSYale College, Chemistry (1995)
Additional Information
Honors & Recognitions
- Lungevity Foundation Early Detection Award: (2015)
- Tina's Wish Foundation Research Award: (2015)
- ASTRO Junior Faculty Career Research Training Award: American Society for Radiation Oncology (2011)
- Brozman Foundation Fellowship: (2011)
- American Cancer Society Institutional Research Grant: (2010)
- YCCI Scholar Award: Yale Center for Clinical Investigation (2010)
- Rudolph Anderson Fellowship: (2009)
- Yale Cancer Center Pilot Research Grant: (2009)
- M.D./Ph.D. Award: Yale School of Medicine (2003)
- Sterling Prize Fellowship: Yale Graduate School of Arts and Sciences (1995)
Publications
- Batool SM, Hsia T, Beecroft A, Lewis B, Ekanayake E, Rosenfeld Y, Escobedo AK, Gamblin AS, Rawal S, Cote RJ, Watson M, Wong DTW, Patel AA, Skog J, Papadopoulos N, Bettegowda C, Castro CM, Lee H, Srivastava S, Carter BS, Balaj L. Extrinsic and intrinsic preanalytical variables affecting liquid biopsy in cancer. Cell Rep Med 2023, 4: 101196. PMID: 37725979, DOI: 10.1016/j.xcrm.2023.101196.
- The Liquid Biopsy Consortium: Challenges and opportunities for early cancer detection and monitoringBatool S, Yekula A, Khanna P, Hsia T, Gamblin A, Ekanayake E, Escobedo A, You D, Castro C, Im H, Kilic T, Garlin M, Skog J, Dinulescu D, Dudley J, Agrawal N, Cheng J, Abtin F, Aberle D, Chia D, Elashoff D, Grognan T, Krysan K, Oh S, Strom C, Tu M, Wei F, Xian R, Skates S, Zhang D, Trinh T, Watson M, Aft R, Rawal S, Agarwal A, Kesmodel S, Yang C, Shen C, Hochberg F, Wong D, Patel A, Papadopoulos N, Bettegowda C, Cote R, Srivastava S, Lee H, Carter B, Balaj L. The Liquid Biopsy Consortium: Challenges and opportunities for early cancer detection and monitoring. Cell Reports Medicine 2023, 4: 101198. PMID: 37716353, PMCID: PMC10591039, DOI: 10.1016/j.xcrm.2023.101198.
- Cheng J, Hu Y, Wong D, Patel A. ctDNA and Lung Cancer. 2023, 511-537. DOI: 10.1007/978-3-031-22903-9_20.
- Tyagi T, Jain K, Yarovinsky TO, Chiorazzi M, Du J, Castro C, Griffin J, Korde A, Martin KA, Takyar SS, Flavell RA, Patel AA, Hwa J. Platelet-derived TLT-1 promotes tumor progression by suppressing CD8+ T cells. Journal Of Experimental Medicine 2022, 220: e20212218. PMID: 36305874, PMCID: PMC9814191, DOI: 10.1084/jem.20212218.
- Cheng LY, Dai P, Wu LR, Patel AA, Zhang DY. Direct capture and sequencing reveal ultra-short single-stranded DNA in biofluids. IScience 2022, 25: 105046. PMID: 36147958, PMCID: PMC9486625, DOI: 10.1016/j.isci.2022.105046.
- Song P, Wu LR, Yan YH, Zhang JX, Chu T, Kwong LN, Patel AA, Zhang DY. Limitations and opportunities of technologies for the analysis of cell-free DNA in cancer diagnostics. Nature Biomedical Engineering 2022, 6: 232-245. PMID: 35102279, PMCID: PMC9336539, DOI: 10.1038/s41551-021-00837-3.
- Hu Y, Narayan A, Wolfe J, Vu D, Thi T, Kantak C, Ivy S, Eder J, LoRusso P, Kim J, Patel A. Dynamics of circulating tumor DNA in patients with advanced solid tumors treated with cediranib and olaparib. Journal Of Clinical Oncology 2021, 39: 3035-3035. DOI: 10.1200/jco.2021.39.15_suppl.3035.
- Song P, Chen SX, Yan YH, Pinto A, Cheng LY, Dai P, Patel AA, Zhang DY. Selective multiplexed enrichment for the detection and quantitation of low-fraction DNA variants via low-depth sequencing. Nature Biomedical Engineering 2021, 5: 690-701. PMID: 33941896, PMCID: PMC9631981, DOI: 10.1038/s41551-021-00713-0.
- Cheok SK, Narayan A, Arnal-Estape A, Gettinger S, Goldberg SB, Kluger HM, Nguyen D, Patel A, Chiang V. Tumor DNA Mutations From Intraparenchymal Brain Metastases Are Detectable in CSF. JCO Precision Oncology 2021, 5: 163-172. PMID: 34250381, PMCID: PMC8232069, DOI: 10.1200/po.20.00292.
- Cheok S, Narayan A, Arnal-Estape A, Patel A, Nguyen D, Chiang V. 35. EVALUATING CSF CIRCULATING TUMOR DNA IN INTRAPARENCHYMAL BRAIN METASTASIS. Neuro-Oncology Advances 2020, 2: ii6-ii6. PMCID: PMC7401400, DOI: 10.1093/noajnl/vdaa073.023.
- Hafez N, Soliman H, Fu S, Gelmon K, Abdul Razak A, Munster P, Vaishampayan U, Kato S, Lara P, Swisher E, Nixon A, Patel A, Shyr Y, Ivy S, LoRusso P, Kim J. Preliminary efficacy data of triple-negative breast cancer cohort of NCI 9881 study: A phase II study of cediranib in combination with olaparib in advanced solid tumors. Journal Of Clinical Oncology 2020, 38: 1077-1077. DOI: 10.1200/jco.2020.38.15_suppl.1077.
- Kim J, Hafez N, Soliman H, Fu S, Kato S, Lara P, Vaishampayan U, Abdul Razak A, Cardin D, Munster P, Eder J, Swisher E, Nixon A, Patel A, Shyr Y, Ivy S, LoRusso P. Preliminary efficacy data of platinum-pretreated small cell lung cancer (SCLC) cohort of NCI 9881 study: A phase II study of cediranib in combination with olaparib in advanced solid tumors. Journal Of Clinical Oncology 2020, 38: 9065-9065. DOI: 10.1200/jco.2020.38.15_suppl.9065.
- Cheok S, Arnal-Estape A, Narayan A, Zakaria M, Goldberg S, Patel A, Nguyen D, Chiang V. Cerebrospinal Fluid Biomarkers of Brain Metastasis. Neurosurgery 2019, 66: 310-631. DOI: 10.1093/neuros/nyz310_631.
- Kole AJ, Park HS, Johnson SB, Kelly JR, Moran MS, Patel AA. Overall survival is improved when DCIS accompanies invasive breast cancer. Scientific Reports 2019, 9: 9934. PMID: 31289308, PMCID: PMC6616329, DOI: 10.1038/s41598-019-46309-2.
- Narayan A, Johnkennedy R, Zakaria M, Lee V, Patel AA. META RNA profiling: Multiplexed quantitation of targeted RNAs across large numbers of samples. Methods 2018, 152: 41-47. PMID: 30308315, PMCID: PMC6311137, DOI: 10.1016/j.ymeth.2018.09.012.
- Goldberg SB, Patel AA. Monitoring immunotherapy outcomes with circulating tumor DNA. Immunotherapy 2018, 10: 1023-1025. PMID: 30185140, DOI: 10.2217/imt-2018-0084.
- Lopez Sambrooks C, Baro M, Quijano A, Narayan A, Cui W, Greninger P, Egan R, Patel A, Benes CH, Saltzman WM, Contessa JN. Oligosaccharyltransferase Inhibition Overcomes Therapeutic Resistance to EGFR Tyrosine Kinase Inhibitors. Cancer Research 2018, 78: canres.0505.2018. PMID: 30026325, PMCID: PMC6125176, DOI: 10.1158/0008-5472.can-18-0505.
- Goldberg SB, Narayan A, Kole AJ, Decker RH, Teysir J, Carriero NJ, Lee A, Nemati R, Nath SK, Mane SM, Deng Y, Sukumar N, Zelterman D, Boffa DJ, Politi K, Gettinger S, Wilson LD, Herbst RS, Patel AA. Early Assessment of Lung Cancer Immunotherapy Response via Circulating Tumor DNA. Clinical Cancer Research 2018, 24: 1872-1880. PMID: 29330207, PMCID: PMC5899677, DOI: 10.1158/1078-0432.ccr-17-1341.
- Han C, Bellone S, Siegel ER, Altwerger G, Menderes G, Bonazzoli E, Egawa-Takata T, Pettinella F, Bianchi A, Riccio F, Zammataro L, Yadav G, Marto JA, Penet MF, Levine DA, Drapkin R, Patel A, Litkouhi B, Ratner E, Silasi DA, Huang GS, Azodi M, Schwartz PE, Santin AD. A novel multiple biomarker panel for the early detection of high-grade serous ovarian carcinoma. Gynecologic Oncology 2018, 149: 585-591. PMID: 29572027, PMCID: PMC5986604, DOI: 10.1016/j.ygyno.2018.03.050.
- Kole A, Park H, Johnson S, Kelly J, Patel A. Breast Cancer Survival is Improved When DCIS Accompanies Invasive Ductal Carcinoma. International Journal Of Radiation Oncology • Biology • Physics 2017, 99: e25. DOI: 10.1016/j.ijrobp.2017.06.651.
- Wu LR, Chen SX, Wu Y, Patel AA, Zhang DY. Multiplexed enrichment of rare DNA variants via sequence-selective and temperature-robust amplification. Nature Biomedical Engineering 2017, 1: 714-723. PMID: 29805844, PMCID: PMC5969535, DOI: 10.1038/s41551-017-0126-5.
- Goldberg S, Narayan A, Kole A, Decker R, Teysir J, Carriero N, Lee A, Nemati R, Nath S, Mane S, Deng Y, Sukumar N, Zelterman D, Boffa D, Politi K, Gettinger S, Wilson L, Herbst R, Patel A. 1341P Assessing response to immunotherapy in patients with non-small cell lung cancer using circulating tumor DNA. Annals Of Oncology 2017, 28: v478. DOI: 10.1093/annonc/mdx380.043.
- Henick B, Goldberg S, Narayan A, Rossi C, Rodney S, Kole A, Politi K, Gettinger S, Herbst R, Patel A. Circulating tumor DNA (ctDNA) to monitor treatment response and progression in patients treated with tyrosine kinase inhibitors (TKIs) and immunotherapy for EGFR-mutant non-small cell lung cancer (NSCLC). Journal Of Clinical Oncology 2017, 35: e20652-e20652. DOI: 10.1200/jco.2017.35.15_suppl.e20652.
- Cecchini M, Salem R, Zaheer Kidwai W, Kortmansky J, Fischbach N, Patel A, Hochster H, Lacy J. Interim analysis of perioperative modified FOLFIRINOX (mFOLFIRINOX) in resectable pancreatic cancer (PC). Journal Of Clinical Oncology 2017, 35: 393-393. DOI: 10.1200/jco.2017.35.4_suppl.393.
- Narayan A, Bommakanti A, Patel AA. High-throughput RNA profiling via up-front sample parallelization. Nature Methods 2015, 12: 343-346. PMID: 25730493, PMCID: PMC4451056, DOI: 10.1038/nmeth.3311.
- Goldberg S, Narayan A, Carriero N, Nemati R, Bommakanti A, Wurtz A, Boffa D, Decker R, Herbst R, Juergensmeier J, Politi K, Gettinger S, Patel A. Detection of sensitizing and resistance EGFR mutations from circulating tumor DNA (ctDNA) in blood using multiplexed next-generation sequencing in patients with advanced EGFR -mutant lung adenocarcinoma. Journal Of Clinical Oncology 2014, 32: 8093-8093. DOI: 10.1200/jco.2014.32.15_suppl.8093.
- James E, Narayan A, Carriero N, Chang B, Lacy J, Stein S, Hochster H, Patel A. Monitoring changes in circulating tumor DNA in gastrointestinal malignancies using a novel next-generation sequencing method. Journal Of Clinical Oncology 2014, 32: 3645-3645. DOI: 10.1200/jco.2014.32.15_suppl.3645.
- James E, Narayan A, Stein S, Lacy J, Patel A, Hochster H. Measurement of circulating tumor DNA as a cancer biomarker in gastrointestinal malignancies using a novel next-generation sequencing method. Journal Of Clinical Oncology 2014, 32: 217-217. DOI: 10.1200/jco.2014.32.3_suppl.217.
- Narayan A, Carriero NJ, Gettinger SN, Kluytenaar J, Kozak KR, Yock TI, Muscato NE, Ugarelli P, Decker RH, Patel AA. Ultrasensitive Measurement of Hotspot Mutations in Tumor DNA in Blood Using Error-Suppressed Multiplexed Deep Sequencing. Cancer Research 2012, 72: 3492-3498. PMID: 22581825, PMCID: PMC3426449, DOI: 10.1158/0008-5472.can-11-4037.
- Patel AA, Wolfgang JA, Niemierko A, Hong TS, Yock T, Choi NC. Implications of Respiratory Motion as Measured by Four-Dimensional Computed Tomography for Radiation Treatment Planning of Esophageal Cancer. International Journal Of Radiation Oncology • Biology • Physics 2009, 74: 290-296. PMID: 19362248, DOI: 10.1016/j.ijrobp.2008.12.060.
- Patel AA, Chen MH, Renshaw AA, D'Amico AV. PSA failure following definitive treatment of prostate cancer having biopsy Gleason score 7 with tertiary grade 5. JAMA 2007, 298: 1533-8. PMID: 17911498, DOI: 10.1001/jama.298.13.1533.
- Patel A, Wolfgang J, Niemierko A, Hong T, Yock T, Choi N. 2715 Implications of Respiratory Motion as Measured by 4D CT for Radiation Treatment Planning of Esophageal Tumors. International Journal Of Radiation Oncology • Biology • Physics 2006, 66: s607. DOI: 10.1016/j.ijrobp.2006.07.1131.
- Flampouri S, Jiang SB, Sharp GC, Wolfgang J, Patel AA, Choi NC. Estimation of the delivered patient dose in lung IMRT treatment based on deformable registration of 4D-CT data and Monte Carlo simulations. Physics In Medicine And Biology 2006, 51: 2763-2779. PMID: 16723765, DOI: 10.1088/0031-9155/51/11/006.
- Choi N, Wolfgang J, Flampouri S, Patel A, Jiang S, Niemierko A, Chen G. 4D CT Planning Improves Tumor Control Probability (TCP) When Compared with Helical CT Scan in 3D Conformal Radiation Therapy (CRT) in Lung Cancer. International Journal Of Radiation Oncology • Biology • Physics 2005, 63: s398. DOI: 10.1016/j.ijrobp.2005.07.678.
- Choi N, Wolfgang J, Flampouri S, Patel A, Jiang S, Niemierko A, Chen G. E16. 4D CT (Computed Tomography) improves TCP without an increase in NTCP of lung when compared with helical CT planning in 3D conformal radiation therapy (CRT) for patients with lung cancer. Lung Cancer 2005, 49: s25-s26. DOI: 10.1016/s0169-5002(05)80079-0.
- Patel AA, Steitz JA. Splicing double: insights from the second spliceosome. Nature Reviews Molecular Cell Biology 2003, 4: 960-970. PMID: 14685174, DOI: 10.1038/nrm1259.
- Patel AA, McCarthy M, Steitz JA. The splicing of U12‐type introns can be a rate‐limiting step in gene expression. The EMBO Journal 2002, 21: 3804-3815. PMID: 12110592, PMCID: PMC126102, DOI: 10.1093/emboj/cdf297.
Locations
Yale Therapeutic Radiology
Lawrence + Memorial Cancer Center
230 Waterford Parkway South
Waterford, CT 06385
- Yale Therapeutic RadiologyLawrence + Memorial Cancer Center230 Waterford Parkway SouthWaterford, CT 06385
Titles
- Associate Professor of Therapeutic Radiology
Education & Training
- Postdoctoral ResearchHHMI, Massachusetts General Hospital (2008)
- ResidencyHarvard Radiation Oncology (2008)
- InternshipMemorial Sloan-Kettering Cancer Center (2004)
- MDYale University School of Medicine (2003)
- PhDYale University Graduate School, Molecular Biophysics and Biochemistry (2002)
- MSYale College, Chemistry (1995)
- BSYale College, Chemistry (1995)
Additional Information
Honors & Recognitions
- Lungevity Foundation Early Detection Award: (2015)
- Tina's Wish Foundation Research Award: (2015)
- ASTRO Junior Faculty Career Research Training Award: American Society for Radiation Oncology (2011)
- Brozman Foundation Fellowship: (2011)
- American Cancer Society Institutional Research Grant: (2010)
- YCCI Scholar Award: Yale Center for Clinical Investigation (2010)
- Rudolph Anderson Fellowship: (2009)
- Yale Cancer Center Pilot Research Grant: (2009)
- M.D./Ph.D. Award: Yale School of Medicine (2003)
- Sterling Prize Fellowship: Yale Graduate School of Arts and Sciences (1995)
Publications
- Batool SM, Hsia T, Beecroft A, Lewis B, Ekanayake E, Rosenfeld Y, Escobedo AK, Gamblin AS, Rawal S, Cote RJ, Watson M, Wong DTW, Patel AA, Skog J, Papadopoulos N, Bettegowda C, Castro CM, Lee H, Srivastava S, Carter BS, Balaj L. Extrinsic and intrinsic preanalytical variables affecting liquid biopsy in cancer. Cell Rep Med 2023, 4: 101196. PMID: 37725979, DOI: 10.1016/j.xcrm.2023.101196.
- The Liquid Biopsy Consortium: Challenges and opportunities for early cancer detection and monitoringBatool S, Yekula A, Khanna P, Hsia T, Gamblin A, Ekanayake E, Escobedo A, You D, Castro C, Im H, Kilic T, Garlin M, Skog J, Dinulescu D, Dudley J, Agrawal N, Cheng J, Abtin F, Aberle D, Chia D, Elashoff D, Grognan T, Krysan K, Oh S, Strom C, Tu M, Wei F, Xian R, Skates S, Zhang D, Trinh T, Watson M, Aft R, Rawal S, Agarwal A, Kesmodel S, Yang C, Shen C, Hochberg F, Wong D, Patel A, Papadopoulos N, Bettegowda C, Cote R, Srivastava S, Lee H, Carter B, Balaj L. The Liquid Biopsy Consortium: Challenges and opportunities for early cancer detection and monitoring. Cell Reports Medicine 2023, 4: 101198. PMID: 37716353, PMCID: PMC10591039, DOI: 10.1016/j.xcrm.2023.101198.
- Cheng J, Hu Y, Wong D, Patel A. ctDNA and Lung Cancer. 2023, 511-537. DOI: 10.1007/978-3-031-22903-9_20.
- Tyagi T, Jain K, Yarovinsky TO, Chiorazzi M, Du J, Castro C, Griffin J, Korde A, Martin KA, Takyar SS, Flavell RA, Patel AA, Hwa J. Platelet-derived TLT-1 promotes tumor progression by suppressing CD8+ T cells. Journal Of Experimental Medicine 2022, 220: e20212218. PMID: 36305874, PMCID: PMC9814191, DOI: 10.1084/jem.20212218.
- Cheng LY, Dai P, Wu LR, Patel AA, Zhang DY. Direct capture and sequencing reveal ultra-short single-stranded DNA in biofluids. IScience 2022, 25: 105046. PMID: 36147958, PMCID: PMC9486625, DOI: 10.1016/j.isci.2022.105046.
- Song P, Wu LR, Yan YH, Zhang JX, Chu T, Kwong LN, Patel AA, Zhang DY. Limitations and opportunities of technologies for the analysis of cell-free DNA in cancer diagnostics. Nature Biomedical Engineering 2022, 6: 232-245. PMID: 35102279, PMCID: PMC9336539, DOI: 10.1038/s41551-021-00837-3.
- Hu Y, Narayan A, Wolfe J, Vu D, Thi T, Kantak C, Ivy S, Eder J, LoRusso P, Kim J, Patel A. Dynamics of circulating tumor DNA in patients with advanced solid tumors treated with cediranib and olaparib. Journal Of Clinical Oncology 2021, 39: 3035-3035. DOI: 10.1200/jco.2021.39.15_suppl.3035.
- Song P, Chen SX, Yan YH, Pinto A, Cheng LY, Dai P, Patel AA, Zhang DY. Selective multiplexed enrichment for the detection and quantitation of low-fraction DNA variants via low-depth sequencing. Nature Biomedical Engineering 2021, 5: 690-701. PMID: 33941896, PMCID: PMC9631981, DOI: 10.1038/s41551-021-00713-0.
- Cheok SK, Narayan A, Arnal-Estape A, Gettinger S, Goldberg SB, Kluger HM, Nguyen D, Patel A, Chiang V. Tumor DNA Mutations From Intraparenchymal Brain Metastases Are Detectable in CSF. JCO Precision Oncology 2021, 5: 163-172. PMID: 34250381, PMCID: PMC8232069, DOI: 10.1200/po.20.00292.
- Cheok S, Narayan A, Arnal-Estape A, Patel A, Nguyen D, Chiang V. 35. EVALUATING CSF CIRCULATING TUMOR DNA IN INTRAPARENCHYMAL BRAIN METASTASIS. Neuro-Oncology Advances 2020, 2: ii6-ii6. PMCID: PMC7401400, DOI: 10.1093/noajnl/vdaa073.023.
- Hafez N, Soliman H, Fu S, Gelmon K, Abdul Razak A, Munster P, Vaishampayan U, Kato S, Lara P, Swisher E, Nixon A, Patel A, Shyr Y, Ivy S, LoRusso P, Kim J. Preliminary efficacy data of triple-negative breast cancer cohort of NCI 9881 study: A phase II study of cediranib in combination with olaparib in advanced solid tumors. Journal Of Clinical Oncology 2020, 38: 1077-1077. DOI: 10.1200/jco.2020.38.15_suppl.1077.
- Kim J, Hafez N, Soliman H, Fu S, Kato S, Lara P, Vaishampayan U, Abdul Razak A, Cardin D, Munster P, Eder J, Swisher E, Nixon A, Patel A, Shyr Y, Ivy S, LoRusso P. Preliminary efficacy data of platinum-pretreated small cell lung cancer (SCLC) cohort of NCI 9881 study: A phase II study of cediranib in combination with olaparib in advanced solid tumors. Journal Of Clinical Oncology 2020, 38: 9065-9065. DOI: 10.1200/jco.2020.38.15_suppl.9065.
- Cheok S, Arnal-Estape A, Narayan A, Zakaria M, Goldberg S, Patel A, Nguyen D, Chiang V. Cerebrospinal Fluid Biomarkers of Brain Metastasis. Neurosurgery 2019, 66: 310-631. DOI: 10.1093/neuros/nyz310_631.
- Kole AJ, Park HS, Johnson SB, Kelly JR, Moran MS, Patel AA. Overall survival is improved when DCIS accompanies invasive breast cancer. Scientific Reports 2019, 9: 9934. PMID: 31289308, PMCID: PMC6616329, DOI: 10.1038/s41598-019-46309-2.
- Narayan A, Johnkennedy R, Zakaria M, Lee V, Patel AA. META RNA profiling: Multiplexed quantitation of targeted RNAs across large numbers of samples. Methods 2018, 152: 41-47. PMID: 30308315, PMCID: PMC6311137, DOI: 10.1016/j.ymeth.2018.09.012.
- Goldberg SB, Patel AA. Monitoring immunotherapy outcomes with circulating tumor DNA. Immunotherapy 2018, 10: 1023-1025. PMID: 30185140, DOI: 10.2217/imt-2018-0084.
- Lopez Sambrooks C, Baro M, Quijano A, Narayan A, Cui W, Greninger P, Egan R, Patel A, Benes CH, Saltzman WM, Contessa JN. Oligosaccharyltransferase Inhibition Overcomes Therapeutic Resistance to EGFR Tyrosine Kinase Inhibitors. Cancer Research 2018, 78: canres.0505.2018. PMID: 30026325, PMCID: PMC6125176, DOI: 10.1158/0008-5472.can-18-0505.
- Goldberg SB, Narayan A, Kole AJ, Decker RH, Teysir J, Carriero NJ, Lee A, Nemati R, Nath SK, Mane SM, Deng Y, Sukumar N, Zelterman D, Boffa DJ, Politi K, Gettinger S, Wilson LD, Herbst RS, Patel AA. Early Assessment of Lung Cancer Immunotherapy Response via Circulating Tumor DNA. Clinical Cancer Research 2018, 24: 1872-1880. PMID: 29330207, PMCID: PMC5899677, DOI: 10.1158/1078-0432.ccr-17-1341.
- Han C, Bellone S, Siegel ER, Altwerger G, Menderes G, Bonazzoli E, Egawa-Takata T, Pettinella F, Bianchi A, Riccio F, Zammataro L, Yadav G, Marto JA, Penet MF, Levine DA, Drapkin R, Patel A, Litkouhi B, Ratner E, Silasi DA, Huang GS, Azodi M, Schwartz PE, Santin AD. A novel multiple biomarker panel for the early detection of high-grade serous ovarian carcinoma. Gynecologic Oncology 2018, 149: 585-591. PMID: 29572027, PMCID: PMC5986604, DOI: 10.1016/j.ygyno.2018.03.050.
- Kole A, Park H, Johnson S, Kelly J, Patel A. Breast Cancer Survival is Improved When DCIS Accompanies Invasive Ductal Carcinoma. International Journal Of Radiation Oncology • Biology • Physics 2017, 99: e25. DOI: 10.1016/j.ijrobp.2017.06.651.
- Wu LR, Chen SX, Wu Y, Patel AA, Zhang DY. Multiplexed enrichment of rare DNA variants via sequence-selective and temperature-robust amplification. Nature Biomedical Engineering 2017, 1: 714-723. PMID: 29805844, PMCID: PMC5969535, DOI: 10.1038/s41551-017-0126-5.
- Goldberg S, Narayan A, Kole A, Decker R, Teysir J, Carriero N, Lee A, Nemati R, Nath S, Mane S, Deng Y, Sukumar N, Zelterman D, Boffa D, Politi K, Gettinger S, Wilson L, Herbst R, Patel A. 1341P Assessing response to immunotherapy in patients with non-small cell lung cancer using circulating tumor DNA. Annals Of Oncology 2017, 28: v478. DOI: 10.1093/annonc/mdx380.043.
- Henick B, Goldberg S, Narayan A, Rossi C, Rodney S, Kole A, Politi K, Gettinger S, Herbst R, Patel A. Circulating tumor DNA (ctDNA) to monitor treatment response and progression in patients treated with tyrosine kinase inhibitors (TKIs) and immunotherapy for EGFR-mutant non-small cell lung cancer (NSCLC). Journal Of Clinical Oncology 2017, 35: e20652-e20652. DOI: 10.1200/jco.2017.35.15_suppl.e20652.
- Cecchini M, Salem R, Zaheer Kidwai W, Kortmansky J, Fischbach N, Patel A, Hochster H, Lacy J. Interim analysis of perioperative modified FOLFIRINOX (mFOLFIRINOX) in resectable pancreatic cancer (PC). Journal Of Clinical Oncology 2017, 35: 393-393. DOI: 10.1200/jco.2017.35.4_suppl.393.
- Narayan A, Bommakanti A, Patel AA. High-throughput RNA profiling via up-front sample parallelization. Nature Methods 2015, 12: 343-346. PMID: 25730493, PMCID: PMC4451056, DOI: 10.1038/nmeth.3311.
- Goldberg S, Narayan A, Carriero N, Nemati R, Bommakanti A, Wurtz A, Boffa D, Decker R, Herbst R, Juergensmeier J, Politi K, Gettinger S, Patel A. Detection of sensitizing and resistance EGFR mutations from circulating tumor DNA (ctDNA) in blood using multiplexed next-generation sequencing in patients with advanced EGFR -mutant lung adenocarcinoma. Journal Of Clinical Oncology 2014, 32: 8093-8093. DOI: 10.1200/jco.2014.32.15_suppl.8093.
- James E, Narayan A, Carriero N, Chang B, Lacy J, Stein S, Hochster H, Patel A. Monitoring changes in circulating tumor DNA in gastrointestinal malignancies using a novel next-generation sequencing method. Journal Of Clinical Oncology 2014, 32: 3645-3645. DOI: 10.1200/jco.2014.32.15_suppl.3645.
- James E, Narayan A, Stein S, Lacy J, Patel A, Hochster H. Measurement of circulating tumor DNA as a cancer biomarker in gastrointestinal malignancies using a novel next-generation sequencing method. Journal Of Clinical Oncology 2014, 32: 217-217. DOI: 10.1200/jco.2014.32.3_suppl.217.
- Narayan A, Carriero NJ, Gettinger SN, Kluytenaar J, Kozak KR, Yock TI, Muscato NE, Ugarelli P, Decker RH, Patel AA. Ultrasensitive Measurement of Hotspot Mutations in Tumor DNA in Blood Using Error-Suppressed Multiplexed Deep Sequencing. Cancer Research 2012, 72: 3492-3498. PMID: 22581825, PMCID: PMC3426449, DOI: 10.1158/0008-5472.can-11-4037.
- Patel AA, Wolfgang JA, Niemierko A, Hong TS, Yock T, Choi NC. Implications of Respiratory Motion as Measured by Four-Dimensional Computed Tomography for Radiation Treatment Planning of Esophageal Cancer. International Journal Of Radiation Oncology • Biology • Physics 2009, 74: 290-296. PMID: 19362248, DOI: 10.1016/j.ijrobp.2008.12.060.
- Patel AA, Chen MH, Renshaw AA, D'Amico AV. PSA failure following definitive treatment of prostate cancer having biopsy Gleason score 7 with tertiary grade 5. JAMA 2007, 298: 1533-8. PMID: 17911498, DOI: 10.1001/jama.298.13.1533.
- Patel A, Wolfgang J, Niemierko A, Hong T, Yock T, Choi N. 2715 Implications of Respiratory Motion as Measured by 4D CT for Radiation Treatment Planning of Esophageal Tumors. International Journal Of Radiation Oncology • Biology • Physics 2006, 66: s607. DOI: 10.1016/j.ijrobp.2006.07.1131.
- Flampouri S, Jiang SB, Sharp GC, Wolfgang J, Patel AA, Choi NC. Estimation of the delivered patient dose in lung IMRT treatment based on deformable registration of 4D-CT data and Monte Carlo simulations. Physics In Medicine And Biology 2006, 51: 2763-2779. PMID: 16723765, DOI: 10.1088/0031-9155/51/11/006.
- Choi N, Wolfgang J, Flampouri S, Patel A, Jiang S, Niemierko A, Chen G. 4D CT Planning Improves Tumor Control Probability (TCP) When Compared with Helical CT Scan in 3D Conformal Radiation Therapy (CRT) in Lung Cancer. International Journal Of Radiation Oncology • Biology • Physics 2005, 63: s398. DOI: 10.1016/j.ijrobp.2005.07.678.
- Choi N, Wolfgang J, Flampouri S, Patel A, Jiang S, Niemierko A, Chen G. E16. 4D CT (Computed Tomography) improves TCP without an increase in NTCP of lung when compared with helical CT planning in 3D conformal radiation therapy (CRT) for patients with lung cancer. Lung Cancer 2005, 49: s25-s26. DOI: 10.1016/s0169-5002(05)80079-0.
- Patel AA, Steitz JA. Splicing double: insights from the second spliceosome. Nature Reviews Molecular Cell Biology 2003, 4: 960-970. PMID: 14685174, DOI: 10.1038/nrm1259.
- Patel AA, McCarthy M, Steitz JA. The splicing of U12‐type introns can be a rate‐limiting step in gene expression. The EMBO Journal 2002, 21: 3804-3815. PMID: 12110592, PMCID: PMC126102, DOI: 10.1093/emboj/cdf297.
Locations
Yale Therapeutic Radiology
Lawrence + Memorial Cancer Center
230 Waterford Parkway South
Waterford, CT 06385
- Yale Therapeutic RadiologyLawrence + Memorial Cancer Center230 Waterford Parkway SouthWaterford, CT 06385
Yale Therapeutic Radiology
Lawrence + Memorial Cancer Center
230 Waterford Parkway South
Waterford, CT 06385
- Yale Therapeutic RadiologyLawrence + Memorial Cancer Center230 Waterford Parkway SouthWaterford, CT 06385