- Yale Therapeutic RadiologyLawrence + Memorial Cancer Center230 Waterford Parkway SouthWaterford, CT 06385
Abhijit Patel, MD, PhD
Therapeutic Radiology
Telehealth is available
Patient type treated
Adult
Accepting new patients
Yes
Referral required
From patients or physicians
Titles
- Associate Professor of Therapeutic Radiology
Education & Training
- Postdoctoral ResearchHHMI, Massachusetts General Hospital (2008)
- ResidencyHarvard Radiation Oncology (2008)
- InternshipMemorial Sloan-Kettering Cancer Center (2004)
- MDYale University School of Medicine (2003)
- PhDYale University Graduate School, Molecular Biophysics and Biochemistry (2002)
- MSYale College, Chemistry (1995)
- BSYale College, Chemistry (1995)
Additional Information
Honors & Recognitions
- Lungevity Foundation Early Detection Award: (2015)
- Tina's Wish Foundation Research Award: (2015)
- ASTRO Junior Faculty Career Research Training Award: American Society for Radiation Oncology (2011)
- Brozman Foundation Fellowship: (2011)
- American Cancer Society Institutional Research Grant: (2010)
- YCCI Scholar Award: Yale Center for Clinical Investigation (2010)
- Rudolph Anderson Fellowship: (2009)
- Yale Cancer Center Pilot Research Grant: (2009)
- M.D./Ph.D. Award: Yale School of Medicine (2003)
- Sterling Prize Fellowship: Yale Graduate School of Arts and Sciences (1995)
Publications
- Song P, Chen SX, Yan YH, Pinto A, Cheng LY, Dai P, Patel AA, Zhang DY. Selective multiplexed enrichment for the detection and quantitation of low-fraction DNA variants via low-depth sequencing. Nature Biomedical Engineering 2021, 5:690-701.
- Cheok SK, Narayan A, Arnal-Estape A, Gettinger S, Goldberg SB, Kluger HM, Nguyen D, Patel A, Chiang V. Tumor DNA Mutations From Intraparenchymal Brain Metastases Are Detectable in CSF. JCO Precision Oncology 2021, 5.
- Narayan A, Johnkennedy R, Zakaria M, Lee V, Patel AA. META RNA profiling: Multiplexed quantitation of targeted RNAs across large numbers of samples. Methods (San Diego, Calif.) 2019, 152:41-47.
- Kole AJ, Park HS, Johnson SB, Kelly JR, Moran MS, Patel AA. Overall survival is improved when DCIS accompanies invasive breast cancer. Scientific Reports 2019, 9:9934.
- Goldberg SB, Narayan A, Kole AJ, Decker RH, Teysir J, Carriero NJ, Lee A, Nemati R, Nath SK, Mane SM, Deng Y, Sukumar N, Zelterman D, Boffa DJ, Politi K, Gettinger S, Wilson LD, Herbst RS, Patel AA. Early Assessment of Lung Cancer Immunotherapy Response via Circulating Tumor DNA. Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research 2018, 24:1872-1880.
- Han C, Bellone S, Siegel ER, Altwerger G, Menderes G, Bonazzoli E, Egawa-Takata T, Pettinella F, Bianchi A, Riccio F, Zammataro L, Yadav G, Marto JA, Penet MF, Levine DA, Drapkin R, Patel A, Litkouhi B, Ratner E, Silasi DA, Huang GS, Azodi M, Schwartz PE, Santin AD. A novel multiple biomarker panel for the early detection of high-grade serous ovarian carcinoma. Gynecologic Oncology 2018, 149:585-591.
- Lopez Sambrooks C, Baro M, Quijano A, Narayan A, Wei C, Greninger P, Egan RK, Patel AA, Benes CH, Saltzman WM, Contessa JN. Oligosaccharyltransferase Inhibition Overcomes Therapeutic Resistance to EGFR Tyrosine Kinase Inhibitors. Cancer Research 2018, 78:5094-5106.
- Goldberg SB, Patel AA. Monitoring immunotherapy outcomes with circulating tumor DNA. Immunotherapy 2018, 10:1023-1025.
- Wu LR, Chen SX, Wu Y, Patel AA, Zhang DY. Multiplexed enrichment of rare DNA variants via sequence-selective and temperature-robust amplification. Nature Biomedical Engineering 2017, 1:714-723.
- Narayan A, Bommakanti A, Patel AA. High-throughput RNA profiling via up-front sample parallelization. Nature Methods 2015, 12:343-6.
- Narayan A, Carriero NJ, Gettinger SN, Kluytenaar J, Kozak KR, Yock TI, Muscato NE, Ugarelli P, Decker RH, Patel AA. Ultrasensitive measurement of hotspot mutations in tumor DNA in blood using error-suppressed multiplexed deep sequencing. Cancer Research 2012, 72:3492-8.
- Patel AA, Wolfgang JA, Niemierko A, Hong TS, Yock T, Choi NC. Implications of respiratory motion as measured by four-dimensional computed tomography for radiation treatment planning of esophageal cancer. International Journal Of Radiation Oncology, Biology, Physics 2009, 74:290-6.
- Patel AA, Chen MH, Renshaw AA, D'Amico AV. PSA failure following definitive treatment of prostate cancer having biopsy Gleason score 7 with tertiary grade 5. JAMA 2007, 298:1533-8.
- Flampouri S, Jiang SB, Sharp GC, Wolfgang J, Patel AA, Choi NC. Estimation of the delivered patient dose in lung IMRT treatment based on deformable registration of 4D-CT data and Monte Carlo simulations. Physics In Medicine And Biology 2006, 51:2763-79.
- Patel AA, Steitz JA. Splicing double: insights from the second spliceosome. Nature Reviews. Molecular Cell Biology 2003, 4:960-70.
- Patel AA, McCarthy M, Steitz JA. The splicing of U12-type introns can be a rate-limiting step in gene expression. The EMBO Journal 2002, 21:3804-15.
Titles
- Associate Professor of Therapeutic Radiology
Education & Training
- Postdoctoral ResearchHHMI, Massachusetts General Hospital (2008)
- ResidencyHarvard Radiation Oncology (2008)
- InternshipMemorial Sloan-Kettering Cancer Center (2004)
- MDYale University School of Medicine (2003)
- PhDYale University Graduate School, Molecular Biophysics and Biochemistry (2002)
- MSYale College, Chemistry (1995)
- BSYale College, Chemistry (1995)
Additional Information
Honors & Recognitions
- Lungevity Foundation Early Detection Award: (2015)
- Tina's Wish Foundation Research Award: (2015)
- ASTRO Junior Faculty Career Research Training Award: American Society for Radiation Oncology (2011)
- Brozman Foundation Fellowship: (2011)
- American Cancer Society Institutional Research Grant: (2010)
- YCCI Scholar Award: Yale Center for Clinical Investigation (2010)
- Rudolph Anderson Fellowship: (2009)
- Yale Cancer Center Pilot Research Grant: (2009)
- M.D./Ph.D. Award: Yale School of Medicine (2003)
- Sterling Prize Fellowship: Yale Graduate School of Arts and Sciences (1995)
Publications
- Song P, Chen SX, Yan YH, Pinto A, Cheng LY, Dai P, Patel AA, Zhang DY. Selective multiplexed enrichment for the detection and quantitation of low-fraction DNA variants via low-depth sequencing. Nature Biomedical Engineering 2021, 5:690-701.
- Cheok SK, Narayan A, Arnal-Estape A, Gettinger S, Goldberg SB, Kluger HM, Nguyen D, Patel A, Chiang V. Tumor DNA Mutations From Intraparenchymal Brain Metastases Are Detectable in CSF. JCO Precision Oncology 2021, 5.
- Narayan A, Johnkennedy R, Zakaria M, Lee V, Patel AA. META RNA profiling: Multiplexed quantitation of targeted RNAs across large numbers of samples. Methods (San Diego, Calif.) 2019, 152:41-47.
- Kole AJ, Park HS, Johnson SB, Kelly JR, Moran MS, Patel AA. Overall survival is improved when DCIS accompanies invasive breast cancer. Scientific Reports 2019, 9:9934.
- Goldberg SB, Narayan A, Kole AJ, Decker RH, Teysir J, Carriero NJ, Lee A, Nemati R, Nath SK, Mane SM, Deng Y, Sukumar N, Zelterman D, Boffa DJ, Politi K, Gettinger S, Wilson LD, Herbst RS, Patel AA. Early Assessment of Lung Cancer Immunotherapy Response via Circulating Tumor DNA. Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research 2018, 24:1872-1880.
- Han C, Bellone S, Siegel ER, Altwerger G, Menderes G, Bonazzoli E, Egawa-Takata T, Pettinella F, Bianchi A, Riccio F, Zammataro L, Yadav G, Marto JA, Penet MF, Levine DA, Drapkin R, Patel A, Litkouhi B, Ratner E, Silasi DA, Huang GS, Azodi M, Schwartz PE, Santin AD. A novel multiple biomarker panel for the early detection of high-grade serous ovarian carcinoma. Gynecologic Oncology 2018, 149:585-591.
- Lopez Sambrooks C, Baro M, Quijano A, Narayan A, Wei C, Greninger P, Egan RK, Patel AA, Benes CH, Saltzman WM, Contessa JN. Oligosaccharyltransferase Inhibition Overcomes Therapeutic Resistance to EGFR Tyrosine Kinase Inhibitors. Cancer Research 2018, 78:5094-5106.
- Goldberg SB, Patel AA. Monitoring immunotherapy outcomes with circulating tumor DNA. Immunotherapy 2018, 10:1023-1025.
- Wu LR, Chen SX, Wu Y, Patel AA, Zhang DY. Multiplexed enrichment of rare DNA variants via sequence-selective and temperature-robust amplification. Nature Biomedical Engineering 2017, 1:714-723.
- Narayan A, Bommakanti A, Patel AA. High-throughput RNA profiling via up-front sample parallelization. Nature Methods 2015, 12:343-6.
- Narayan A, Carriero NJ, Gettinger SN, Kluytenaar J, Kozak KR, Yock TI, Muscato NE, Ugarelli P, Decker RH, Patel AA. Ultrasensitive measurement of hotspot mutations in tumor DNA in blood using error-suppressed multiplexed deep sequencing. Cancer Research 2012, 72:3492-8.
- Patel AA, Wolfgang JA, Niemierko A, Hong TS, Yock T, Choi NC. Implications of respiratory motion as measured by four-dimensional computed tomography for radiation treatment planning of esophageal cancer. International Journal Of Radiation Oncology, Biology, Physics 2009, 74:290-6.
- Patel AA, Chen MH, Renshaw AA, D'Amico AV. PSA failure following definitive treatment of prostate cancer having biopsy Gleason score 7 with tertiary grade 5. JAMA 2007, 298:1533-8.
- Flampouri S, Jiang SB, Sharp GC, Wolfgang J, Patel AA, Choi NC. Estimation of the delivered patient dose in lung IMRT treatment based on deformable registration of 4D-CT data and Monte Carlo simulations. Physics In Medicine And Biology 2006, 51:2763-79.
- Patel AA, Steitz JA. Splicing double: insights from the second spliceosome. Nature Reviews. Molecular Cell Biology 2003, 4:960-70.
- Patel AA, McCarthy M, Steitz JA. The splicing of U12-type introns can be a rate-limiting step in gene expression. The EMBO Journal 2002, 21:3804-15.
- Yale Therapeutic RadiologyLawrence + Memorial Cancer Center230 Waterford Parkway SouthWaterford, CT 06385