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Phase I

Study of CD19-targeted NEX-T CAR T Cells in Participants with Relapsing Forms of Multiple Sclerosis (RMS) or Progressive Forms of Multiple Sclerosis (PMS)

  • Study HIC#:2000037550
  • Last Updated:05/15/2025

We are looking for people 18 to 50 years old with a diagnosis of relapsing multiple sclerosis (RMS), including relapsing-remitting MS (RRMS) and active secondary progressive MS (SPMS), as well as those 18 to 60 with a diagnosis of progressive multiple sclerosis (PMS), including primary progressive MS (PPMS) and/or inactive SPMS, to take part in a clinical research study.

Participants will receive the investigational therapy, study-related medical exams, and study-related laboratory tests at no cost. Reimbursement for travel and other out-of-pocket expenses will be available in addition to possible compensation for time.

To learn more and see if you may qualify, visit BMSStudyConnect.com/MSCARTpatient.

  • Age18 years - 60 years
  • GenderBoth

Contact Us

For more information about this study, including how to volunteer, contact:

Help Us Discover!

You can help our team find trials you might be eligible for by creating a volunteer profile in MyChart. To get started, create a volunteer profile, or contact helpusdiscover@yale.edu, or call +18779788343 for more information.

Trial Purpose and Description

We are looking for people 18 to 50 years old with a diagnosis of relapsing multiple sclerosis (RMS), including relapsing-remitting MS (RRMS) and active secondary progressive MS (SPMS), as well as those 18 to 60 with a diagnosis of progressive multiple sclerosis (PMS), including primary progressive MS (PPMS) and/or inactive SPMS, to take part in a clinical research study.

Participants will receive the investigational therapy, study-related medical exams, and study-related laboratory tests at no cost. Reimbursement for travel and other out-of-pocket expenses will be available in addition to possible compensation for time.

To learn more and see if you may qualify, visit BMSStudyConnect.com/MSCARTpatient.

Eligibility Criteria

18 to 50 years old with a diagnosis of relapsing multiple sclerosis (RMS), including relapsing-remitting MS (RRMS) and active secondary progressive MS (SPMS), as well as those 18 to 60 with a diagnosis of progressive multiple sclerosis (PMS), including primary progressive MS (PPMS) and/or inactive SPMS.

Principal Investigator

Sub-Investigators

For more information about this study, including how to volunteer, contact: