- Yale Dermatology New HavenDoctors Building2 Church Street SouthNew Haven, CT 06519
William Damsky, MD, PhD
Biography
William Damsky, MD, PhD, is a dermatologist at Yale Medicine specializing in skin conditions such as psoriasis, eczema, acne, skin cancer, and such rare skin conditions as sarcoidosis, granuloma annulare, necrobiosis lipoidica, and others . He also conducts research on new treatments for these conditions, especially a new class of medications called JAK inhibitors, which inhibit a specific protein responsible for the immune reactions that cause certain rashes.
As a clinician, Dr. Damsky’s goal is to guide patients through the decision-making process to choose an effective therapy that is right for them. While conservative by nature, he also utilizes more aggressive approaches when needed, as long as the patient is comfortable with the decision and is a candidate for the treatment.
Dr. Damsky first became interested in skin conditions when he conducted research on skin cancer and learned about rare skin diseases. “I really like trying to understand rashes and skin conditions that most people haven’t even heard of. Finding treatments for patients who have been told that nothing can be done is really gratifying,” he says.
Titles
- Assistant Professor in Dermatology and Dermatopathology
Education & Training
- FellowYale School of Medicine (2020)
- ResidentYale New Haven Hospital / Yale School of Medicine (2017)
- InternshipYale New Haven Hospital (2014)
- MDUniversity of Vermont, College of Medicine (2013)
- PhDUniversity of Vermont College of Medicine (2011)
- BSUniversity of Vermont (2005)
Additional Information
- Young Investigator Award: American Society for Clinical Investigation (2022)
- 2022 Young Physician-Scientist Award: American Society for Clinical Investigation (2022)
- Young Investigator Award: American Academy of Dermatology (2020)
- Todd Nagel Memorial Award: Skin Cancer Foundation (2018)
- Career Development Award: Dermatology Foundation (2017)
- Physician Scientist Career Development Award: Dermatology Foundation (2017)
- Dermatologist Investigator Research Fellowship: Dermatology Foundation (2016)
- Joseph B Warshaw Award: University of Vermont College of Medicine (2012)
- Research Scholar Award: Joanna Nicolay Melanoma Research Foundation (2010)
- Lyman S Rowell Award: University of Vermont, Department of Biology (2004)
- AB of Dermatology, Dermatology (2017)
- Girardi M, Ren J, Qu R, Rahman N, Lewis J, King A, Liao X, Mirza F, Carlson K, Huang Y, Gigante S, Evans B, Rajendran B, Xu S, Wang G, Foss F, Damsky W, Kluger Y, Krishnaswamy S. Integrated transcriptome and trajectory analysis of cutaneous T-cell lymphoma identifies putative precancer populations Blood Advances 2023, 7: 445-457. PMID: 35947128, PMCID: PMC9979716, DOI: 10.1182/bloodadvances.2022008168.
- Joel M, Fan R, Damsky W, Cohen J. Psoriasis associated with asthma and allergic rhinitis: a US-based cross-sectional study using the All of US Research Program Archives Of Dermatological Research 2023, 1-4. PMID: 36707438, DOI: 10.1007/s00403-023-02539-z.
- Hodelin C, Fan R, Damsky W, Cohen J. The association of atopic dermatitis and chronic rhinosinusitis in adults: a cross‐sectional study using the All of Us research program International Journal Of Dermatology 2022 PMID: 36468789, DOI: 10.1111/ijd.16544.
- Ahmad M, Murphy M, Damsky W, Leventhal J. Dupilumab‐induced psoriasis in the setting of pembrolizumab therapy: an analysis of cytokine expression International Journal Of Dermatology 2022 PMID: 36468831, DOI: 10.1111/ijd.16538.
- Belzer A, Leasure A, Damsky W, Cohen J. The association of anxiety with granuloma annulare: a case-control study of the National Institutes of Health 'All of Us' research programme. British Journal Of Dermatology 2022 PMID: 36715356, DOI: 10.1093/bjd/ljac114.
- Association of sarcoidosis with psoriasis: a cross-sectional study in the All of Us research programMurphy M, Leasure A, Damsky W, Cohen J. Association of sarcoidosis with psoriasis: a cross-sectional study in the All of Us research program Archives Of Dermatological Research 2022, 1-3. PMID: 36436011, DOI: 10.1007/s00403-022-02488-z.
- Fan R, Leasure A, Damsky W, Cohen J. Migraine among adults with atopic dermatitis: a cross-sectional study in the All of Us research programme. Clinical And Experimental Dermatology 2022, 48: 24-26. PMID: 36669173, DOI: 10.1093/ced/llac004.
- Clark A, Murphy M, King B, Cohen J, Rosenbach M, Barbieri J, Damsky W. Patient perspectives on the lived experience of granuloma annulare. British Journal Of Dermatology 2022, 188: 134-136. PMID: 36689498, DOI: 10.1093/bjd/ljac004.
- A case of eosinophilic dermatosis of hematologic malignancy with tissue-based Th2 cytokine profilingXu S, Singh K, McNiff J, Damsky W, Gehlhausen J. A case of eosinophilic dermatosis of hematologic malignancy with tissue-based Th2 cytokine profiling JAAD Case Reports 2022, 30: 5-7. PMID: 36345409, PMCID: PMC9636011, DOI: 10.1016/j.jdcr.2022.09.020.
- Belzer A, Leasure A, Damsky W. 35151 The association of major depressive disorder and anxiety with granuloma annulare: A case-control study of the NIH All of Us database Journal Of The American Academy Of Dermatology 2022, 87: ab116. DOI: 10.1016/j.jaad.2022.06.498.
- Fan R, Leasure A, Damsky W, Cohen J. 187 Mental health comorbidities and alcohol use disorder in atopic dermatitis: A case-control study in the All of Us research program Journal Of Investigative Dermatology 2022, 142: s32. DOI: 10.1016/j.jid.2022.05.194.
- Shipman W, Singh K, Cohen J, Leventhal J, Damsky W, Tomayko M. 030 Immune checkpoint inhibitor-induced bullous pemphigoid skin has elevated interleukin-4 and interleukin-13 expression and responds to IL-4R inhibition Journal Of Investigative Dermatology 2022, 142: s5. DOI: 10.1016/j.jid.2022.05.084.
- Choi R, Wang J, Damsky W, Wang A, Galan A, Leventhal J. 103 JAK-STAT activation in anti-PD-1 therapy-associated granuloma annulare Journal Of Investigative Dermatology 2022, 142: s18. DOI: 10.1016/j.jid.2022.05.038.
- Singh K, Valido K, Swallow M, Cohen J, Damsky W. 814 Correlation between skin cytokine profile and response to dupilumab in atopic dermatitis Journal Of Investigative Dermatology 2022, 142: s141. DOI: 10.1016/j.jid.2022.05.828.
- McGeary M, Damsky W, Daniels D, Micevic G, Song E, Lou H, Calderwood C, Paradkar S, Iwasaki A, Calderwood D, Turk B, Bosenberg M. Abstract 1380: Setdb1 -loss reactivates ERV expression and interferon signaling to induce immune-mediated melanoma clearance Cancer Research 2022, 82: 1380-1380. DOI: 10.1158/1538-7445.am2022-1380.
- Daniels A, Damsky W, McGeary M, Iwasaki A, Bosenberg M. Abstract 1357: T cell memory and the critical effectors of successful anticancer immune response Cancer Research 2022, 82: 1357-1357. DOI: 10.1158/1538-7445.am2022-1357.
- Ricardo-Gonzalez R, Kotas M, O’Leary C, Tenvooren I, Marquez D, Singh K, Damsky W, Liao C, Schroeder A, Cohen J, Fassett M, Lee J, Daniel S, Bittinger K, Diaz R, Fraser J, Ansel K, Spitzer M, Liang H, Locksley R. Innate type 2 immunity controls hair follicle commensalism by Demodex mites The Journal Of Immunology 2022, 208: 50.39-50.39. DOI: 10.4049/jimmunol.208.supp.50.39.
- Gehlhausen JR, Little AJ, Ko CJ, Emmenegger M, Lucas C, Wong P, Klein J, Lu P, Mao T, Jaycox J, Wang E, Ugwu N, Muenker C, Mekael D, Klein R, Patrignelli R, Antaya R, McNiff J, Damsky W, Kamath K, Shon J, Ring A, Yildirim I, Omer S, Ko A, Aguzzi A, Iwasaki A, Obaid A, Lu-Culligan A, Nelson A, Brito A, Nunez A, Martin A, Watkins A, Geng B, Kalinich C, Harden C, Todeasa C, Jensen C, Kim D, McDonald D, Shepard D, Courchaine E, White E, Song E, Silva E, Kudo E, DeIuliis G, Rahming H, Park H, Matos I, Nouws J, Valdez J, Fauver J, Lim J, Rose K, Anastasio K, Brower K, Glick L, Sharma L, Sewanan L, Knaggs L, Minasyan M, Batsu M, Petrone M, Kuang M, Nakahata M, Campbell M, Linehan M, Askenase M, Simonov M, Smolgovsky M, Sonnert N, Naushad N, Vijayakumar P, Martinello R, Datta R, Handoko R, Bermejo S, Prophet S, Bickerton S, Velazquez S, Alpert T, Rice T, Khoury-Hanold W, Peng X, Yang Y, Cao Y, Strong Y. Lack of association between pandemic chilblains and SARS-CoV-2 infection Proceedings Of The National Academy Of Sciences Of The United States Of America 2022, 119: e2122090119. PMID: 35217624, PMCID: PMC8892496, DOI: 10.1073/pnas.2122090119.
- Pazdrak B, Mak D, Damsky W, Bosenberg M, Lochmann B, Gubin M, McQuade J. Abstract 70: Obesity-induced impairment of antitumor immunity is associated with an immunosuppressive tumor immune landscape Cancer Research 2021, 81: 70-70. DOI: 10.1158/1538-7445.am2021-70.
- Mirza F, Wang A, Ramachandran S, Damsky W, Cohen J. Dupilumab‐induced phenotype switch from atopic dermatitis to psoriasis is characterized by de novo interleukin‐17A expression: a case report British Journal Of Dermatology 2021, 185: 432-434. PMID: 33730377, DOI: 10.1111/bjd.20064.
- Wang A, King B, Damsky W. 674 Single-cell RNA sequencing (scRNA-seq) of sarcoidosis skin biopsies reveals key pathogenic cytokines and potential treatment targets Journal Of Investigative Dermatology 2021, 141: s117. DOI: 10.1016/j.jid.2021.02.704.
- Zhou T, Weizman O, Damsky W, McGeary M, Bosenberg M, Ring A. Abstract 2156: IL-18 pathway agonism expands intratumoral PD1+ Tcf1+ stem-like CD8+ cells and their polyfunctional effector progeny to promote anti-tumor immunity Cancer Research 2020, 80: 2156-2156. DOI: 10.1158/1538-7445.am2020-2156.
- Weizman O, Zhou T, Damsky W, McGeary M, Bosenberg M, Ring A. Abstract 3424: IL-18 immunotherapy is efficacious against checkpoint-immunotherapy refractory tumors by promoting the maturation of highly proliferative, polyfunctional NK cells Cancer Research 2020, 80: 3424-3424. DOI: 10.1158/1538-7445.am2020-3424.
- Zhou T, Damsky W, Weizman OE, McGeary MK, Hartmann KP, Rosen CE, Fischer S, Jackson R, Flavell RA, Wang J, Sanmamed MF, Bosenberg MW, Ring AM. IL-18BP is a secreted immune checkpoint and barrier to IL-18 immunotherapy Nature 2020, 583: 609-614. PMID: 32581358, PMCID: PMC7381364, DOI: 10.1038/s41586-020-2422-6.
- Damsky W, Wang A, Olamiju B, Peterson D, Galan A, King B. Treatment of severe lichen planus with the JAK inhibitor tofacitinib Journal Of Allergy And Clinical Immunology 2020, 145: 1708-1710.e2. PMID: 32018031, DOI: 10.1016/j.jaci.2020.01.031.
- Damsky W, Patel D, Garelli CJ, Garg M, Wang A, Dresser K, Deng A, Harris JE, Richmond J, King B. JAK inhibition prevents bleomycin-induced fibrosis in mice and is effective in morphea patients Journal Of Investigative Dermatology 2020, 140: 1446-1449.e4. PMID: 31954727, DOI: 10.1016/j.jid.2019.12.019.
- Krykbaeva I, Damsky W, Turner N, Perry C, Kluger H, Bosenberg M. LB1122 Myeloid targeting in combination with PD1 inhibition boosts anti-tumor immunity in melanoma Journal Of Investigative Dermatology 2019, 139: b19. DOI: 10.1016/j.jid.2019.06.089.
- Ramseier J, Charos A, Park K, Damsky W, Bosenberg M. Abstract 4622: The YUMMER.G mouse melanoma model recapitulates the heterogeneous response to immune checkpoint blockade based on patient sex 2019, 4622-4622. DOI: 10.1158/1538-7445.sabcs18-4622.
- Ramseier J, Charos A, Park K, Damsky W, Bosenberg M. Abstract 4622: The YUMMER.G mouse melanoma model recapitulates the heterogeneous response to immune checkpoint blockade based on patient sex Cancer Research 2019, 79: 4622-4622. DOI: 10.1158/1538-7445.am2019-4622.
- Damsky W, Thakral D, McGeary MK, Leventhal J, Galan A, King B. Janus kinase inhibition induces disease remission in cutaneous sarcoidosis and granuloma annulare Journal Of The American Academy Of Dermatology 2019, 82: 612-621. PMID: 31185230, PMCID: PMC7590533, DOI: 10.1016/j.jaad.2019.05.098.
- Ferreira M, Krykbaeva I, Damsky W, Kluger H, Bosenberg M. Evaluating the role of the COX2/PGE2 pathway in anti-melanoma immunity. Journal Of Clinical Oncology 2019, 37: e14114-e14114. DOI: 10.1200/jco.2019.37.15_suppl.e14114.
- Ferreira M, Damsky W, Bosenberg M. 783 Evaluating the impact of high-dose steroids on checkpoint inhibitor efficacy in a murine model of melanoma Journal Of Investigative Dermatology 2019, 139: s135. DOI: 10.1016/j.jid.2019.03.859.
- Ramseier J, Thakral D, Damsky W, Bosenberg M. 789 Immune checkpoint therapy polarizes fibroblasts into a proinflammatory state Journal Of Investigative Dermatology 2019, 139: s136. DOI: 10.1016/j.jid.2019.03.865.
- Damsky W, Thakral D, Emeagwali N, Galan A, King B. Tofacitinib Treatment and Molecular Analysis of Cutaneous Sarcoidosis New England Journal Of Medicine 2018, 379: 2540-2546. PMID: 30586518, PMCID: PMC6351852, DOI: 10.1056/nejmoa1805958.
- Turner N, Damsky W, Wang J, Meeth K, Blenman K, Bosenberg M. 1245 PD-1 blockade impedes tumor growth in the immunogenic YUMMER1.7 mouse melanoma model Journal Of Investigative Dermatology 2018, 138: s211. DOI: 10.1016/j.jid.2018.03.1260.
- Wang J, Perry CJ, Meeth K, Thakral D, Damsky W, Micevic G, Kaech S, Blenman K, Bosenberg M. UV‐induced somatic mutations elicit a functional T cell response in the YUMMER1.7 mouse melanoma model Pigment Cell & Melanoma Research 2017, 30: 428-435. PMID: 28379630, PMCID: PMC5820096, DOI: 10.1111/pcmr.12591.
- Damsky W, Wang J, Perry C, Meeth K, Kaech S, Bosenberg M. 766 Exposure to ultraviolet light enhances anti-tumor immunity and response to immunotherapy in a mouse model of melanoma Journal Of Investigative Dermatology 2017, 137: s132. DOI: 10.1016/j.jid.2017.02.791.
- Damsky W, King BA. JAK inhibitors in dermatology: The promise of a new drug class Journal Of The American Academy Of Dermatology 2017, 76: 736-744. PMID: 28139263, PMCID: PMC6035868, DOI: 10.1016/j.jaad.2016.12.005.
- Meeth K, Wang JX, Micevic G, Damsky W, Bosenberg MW. The YUMM lines: a series of congenic mouse melanoma cell lines with defined genetic alterations Pigment Cell & Melanoma Research 2016, 29: 590-597. PMID: 27287723, PMCID: PMC5331933, DOI: 10.1111/pcmr.12498.
- Bosenberg M, Meeth K, Damsky W. A comprehensive system of congenic mouse melanoma models for evaluation of immune therapies The Journal Of Immunology 2016, 196: 144.19-144.19. DOI: 10.4049/jimmunol.196.supp.144.19.
- Meeth K, Damsky W, Bosenberg M. Abstract 5141: A comprehensive system of congenic mouse melanoma models for evaluation of immune therapies 2015, 5141-5141. DOI: 10.1158/1538-7445.am2015-5141.
- Damsky W, Micevic G, Meeth K, Muthusamy V, Curley DP, Santhanakrishnan M, Erdelyi I, Platt JT, Huang L, Theodosakis N, Zaidi MR, Tighe S, Davies MA, Dankort D, McMahon M, Merlino G, Bardeesy N, Bosenberg M. mTORC1 Activation Blocks Braf V600E -Induced Growth Arrest but Is Insufficient for Melanoma Formation Cancer Cell 2015, 27: 41-56. PMID: 25584893, PMCID: PMC4295062, DOI: 10.1016/j.ccell.2014.11.014.
- Maniecki M, Etzerodt A, Damsky W, Rafique A, Gonzalez D, Dyrskjøt L, Møller H, Bosenberg M, Moestrup S. Abstract 1534: CD163-expressing macrophages constitute a distinct malignancy-promoting phenotype in melanoma facilitating tumor development, progression, and metastasis: Implications for novel anticancer therapy. Cancer Research 2013, 73: 1534-1534. DOI: 10.1158/1538-7445.am2013-1534.
- Damsky WE, Curley DP, Santhanakrishnan M, Rosenbaum LE, Platt JT, Rothberg B, Taketo MM, Dankort D, Rimm DL, McMahon M, Bosenberg M. β-Catenin Signaling Controls Metastasis in Braf-Activated Pten-Deficient Melanomas Cancer Cell 2011, 20: 741-754. PMID: 22172720, PMCID: PMC3241928, DOI: 10.1016/j.ccr.2011.10.030.
- Rosenbaum L, Damsky W, Bosenberg M. Abstract 3377: The effect of E-cadherin loss on melanoma formation and metastasis in a conditional mouse model Cancer Research 2011, 71: 3377-3377. DOI: 10.1158/1538-7445.am2011-3377.
- Maniecki M, Damsky W, Ulhøi B, Steiniche T, Ørntoft T, Dyrskjøt L, Borre M, Kjeldsen E, Bosenberg M, Møller H. Abstract 539: The expression of monocyte/macrophage-restricted scavenger receptor CD163 by malignant cells may be a consequence of cell fusion with tumor-associated macrophages: A novel target for cancer therapy Cancer Research 2011, 71: 539-539. DOI: 10.1158/1538-7445.am2011-539.
Biography
William Damsky, MD, PhD, is a dermatologist at Yale Medicine specializing in skin conditions such as psoriasis, eczema, acne, skin cancer, and such rare skin conditions as sarcoidosis, granuloma annulare, necrobiosis lipoidica, and others . He also conducts research on new treatments for these conditions, especially a new class of medications called JAK inhibitors, which inhibit a specific protein responsible for the immune reactions that cause certain rashes.
As a clinician, Dr. Damsky’s goal is to guide patients through the decision-making process to choose an effective therapy that is right for them. While conservative by nature, he also utilizes more aggressive approaches when needed, as long as the patient is comfortable with the decision and is a candidate for the treatment.
Dr. Damsky first became interested in skin conditions when he conducted research on skin cancer and learned about rare skin diseases. “I really like trying to understand rashes and skin conditions that most people haven’t even heard of. Finding treatments for patients who have been told that nothing can be done is really gratifying,” he says.
Titles
- Assistant Professor in Dermatology and Dermatopathology
Education & Training
- FellowYale School of Medicine (2020)
- ResidentYale New Haven Hospital / Yale School of Medicine (2017)
- InternshipYale New Haven Hospital (2014)
- MDUniversity of Vermont, College of Medicine (2013)
- PhDUniversity of Vermont College of Medicine (2011)
- BSUniversity of Vermont (2005)
Additional Information
- Young Investigator Award: American Society for Clinical Investigation (2022)
- 2022 Young Physician-Scientist Award: American Society for Clinical Investigation (2022)
- Young Investigator Award: American Academy of Dermatology (2020)
- Todd Nagel Memorial Award: Skin Cancer Foundation (2018)
- Career Development Award: Dermatology Foundation (2017)
- Physician Scientist Career Development Award: Dermatology Foundation (2017)
- Dermatologist Investigator Research Fellowship: Dermatology Foundation (2016)
- Joseph B Warshaw Award: University of Vermont College of Medicine (2012)
- Research Scholar Award: Joanna Nicolay Melanoma Research Foundation (2010)
- Lyman S Rowell Award: University of Vermont, Department of Biology (2004)
- AB of Dermatology, Dermatology (2017)
- Girardi M, Ren J, Qu R, Rahman N, Lewis J, King A, Liao X, Mirza F, Carlson K, Huang Y, Gigante S, Evans B, Rajendran B, Xu S, Wang G, Foss F, Damsky W, Kluger Y, Krishnaswamy S. Integrated transcriptome and trajectory analysis of cutaneous T-cell lymphoma identifies putative precancer populations Blood Advances 2023, 7: 445-457. PMID: 35947128, PMCID: PMC9979716, DOI: 10.1182/bloodadvances.2022008168.
- Joel M, Fan R, Damsky W, Cohen J. Psoriasis associated with asthma and allergic rhinitis: a US-based cross-sectional study using the All of US Research Program Archives Of Dermatological Research 2023, 1-4. PMID: 36707438, DOI: 10.1007/s00403-023-02539-z.
- Hodelin C, Fan R, Damsky W, Cohen J. The association of atopic dermatitis and chronic rhinosinusitis in adults: a cross‐sectional study using the All of Us research program International Journal Of Dermatology 2022 PMID: 36468789, DOI: 10.1111/ijd.16544.
- Ahmad M, Murphy M, Damsky W, Leventhal J. Dupilumab‐induced psoriasis in the setting of pembrolizumab therapy: an analysis of cytokine expression International Journal Of Dermatology 2022 PMID: 36468831, DOI: 10.1111/ijd.16538.
- Belzer A, Leasure A, Damsky W, Cohen J. The association of anxiety with granuloma annulare: a case-control study of the National Institutes of Health 'All of Us' research programme. British Journal Of Dermatology 2022 PMID: 36715356, DOI: 10.1093/bjd/ljac114.
- Association of sarcoidosis with psoriasis: a cross-sectional study in the All of Us research programMurphy M, Leasure A, Damsky W, Cohen J. Association of sarcoidosis with psoriasis: a cross-sectional study in the All of Us research program Archives Of Dermatological Research 2022, 1-3. PMID: 36436011, DOI: 10.1007/s00403-022-02488-z.
- Fan R, Leasure A, Damsky W, Cohen J. Migraine among adults with atopic dermatitis: a cross-sectional study in the All of Us research programme. Clinical And Experimental Dermatology 2022, 48: 24-26. PMID: 36669173, DOI: 10.1093/ced/llac004.
- Clark A, Murphy M, King B, Cohen J, Rosenbach M, Barbieri J, Damsky W. Patient perspectives on the lived experience of granuloma annulare. British Journal Of Dermatology 2022, 188: 134-136. PMID: 36689498, DOI: 10.1093/bjd/ljac004.
- A case of eosinophilic dermatosis of hematologic malignancy with tissue-based Th2 cytokine profilingXu S, Singh K, McNiff J, Damsky W, Gehlhausen J. A case of eosinophilic dermatosis of hematologic malignancy with tissue-based Th2 cytokine profiling JAAD Case Reports 2022, 30: 5-7. PMID: 36345409, PMCID: PMC9636011, DOI: 10.1016/j.jdcr.2022.09.020.
- Belzer A, Leasure A, Damsky W. 35151 The association of major depressive disorder and anxiety with granuloma annulare: A case-control study of the NIH All of Us database Journal Of The American Academy Of Dermatology 2022, 87: ab116. DOI: 10.1016/j.jaad.2022.06.498.
- Fan R, Leasure A, Damsky W, Cohen J. 187 Mental health comorbidities and alcohol use disorder in atopic dermatitis: A case-control study in the All of Us research program Journal Of Investigative Dermatology 2022, 142: s32. DOI: 10.1016/j.jid.2022.05.194.
- Shipman W, Singh K, Cohen J, Leventhal J, Damsky W, Tomayko M. 030 Immune checkpoint inhibitor-induced bullous pemphigoid skin has elevated interleukin-4 and interleukin-13 expression and responds to IL-4R inhibition Journal Of Investigative Dermatology 2022, 142: s5. DOI: 10.1016/j.jid.2022.05.084.
- Choi R, Wang J, Damsky W, Wang A, Galan A, Leventhal J. 103 JAK-STAT activation in anti-PD-1 therapy-associated granuloma annulare Journal Of Investigative Dermatology 2022, 142: s18. DOI: 10.1016/j.jid.2022.05.038.
- Singh K, Valido K, Swallow M, Cohen J, Damsky W. 814 Correlation between skin cytokine profile and response to dupilumab in atopic dermatitis Journal Of Investigative Dermatology 2022, 142: s141. DOI: 10.1016/j.jid.2022.05.828.
- McGeary M, Damsky W, Daniels D, Micevic G, Song E, Lou H, Calderwood C, Paradkar S, Iwasaki A, Calderwood D, Turk B, Bosenberg M. Abstract 1380: Setdb1 -loss reactivates ERV expression and interferon signaling to induce immune-mediated melanoma clearance Cancer Research 2022, 82: 1380-1380. DOI: 10.1158/1538-7445.am2022-1380.
- Daniels A, Damsky W, McGeary M, Iwasaki A, Bosenberg M. Abstract 1357: T cell memory and the critical effectors of successful anticancer immune response Cancer Research 2022, 82: 1357-1357. DOI: 10.1158/1538-7445.am2022-1357.
- Ricardo-Gonzalez R, Kotas M, O’Leary C, Tenvooren I, Marquez D, Singh K, Damsky W, Liao C, Schroeder A, Cohen J, Fassett M, Lee J, Daniel S, Bittinger K, Diaz R, Fraser J, Ansel K, Spitzer M, Liang H, Locksley R. Innate type 2 immunity controls hair follicle commensalism by Demodex mites The Journal Of Immunology 2022, 208: 50.39-50.39. DOI: 10.4049/jimmunol.208.supp.50.39.
- Gehlhausen JR, Little AJ, Ko CJ, Emmenegger M, Lucas C, Wong P, Klein J, Lu P, Mao T, Jaycox J, Wang E, Ugwu N, Muenker C, Mekael D, Klein R, Patrignelli R, Antaya R, McNiff J, Damsky W, Kamath K, Shon J, Ring A, Yildirim I, Omer S, Ko A, Aguzzi A, Iwasaki A, Obaid A, Lu-Culligan A, Nelson A, Brito A, Nunez A, Martin A, Watkins A, Geng B, Kalinich C, Harden C, Todeasa C, Jensen C, Kim D, McDonald D, Shepard D, Courchaine E, White E, Song E, Silva E, Kudo E, DeIuliis G, Rahming H, Park H, Matos I, Nouws J, Valdez J, Fauver J, Lim J, Rose K, Anastasio K, Brower K, Glick L, Sharma L, Sewanan L, Knaggs L, Minasyan M, Batsu M, Petrone M, Kuang M, Nakahata M, Campbell M, Linehan M, Askenase M, Simonov M, Smolgovsky M, Sonnert N, Naushad N, Vijayakumar P, Martinello R, Datta R, Handoko R, Bermejo S, Prophet S, Bickerton S, Velazquez S, Alpert T, Rice T, Khoury-Hanold W, Peng X, Yang Y, Cao Y, Strong Y. Lack of association between pandemic chilblains and SARS-CoV-2 infection Proceedings Of The National Academy Of Sciences Of The United States Of America 2022, 119: e2122090119. PMID: 35217624, PMCID: PMC8892496, DOI: 10.1073/pnas.2122090119.
- Pazdrak B, Mak D, Damsky W, Bosenberg M, Lochmann B, Gubin M, McQuade J. Abstract 70: Obesity-induced impairment of antitumor immunity is associated with an immunosuppressive tumor immune landscape Cancer Research 2021, 81: 70-70. DOI: 10.1158/1538-7445.am2021-70.
- Mirza F, Wang A, Ramachandran S, Damsky W, Cohen J. Dupilumab‐induced phenotype switch from atopic dermatitis to psoriasis is characterized by de novo interleukin‐17A expression: a case report British Journal Of Dermatology 2021, 185: 432-434. PMID: 33730377, DOI: 10.1111/bjd.20064.
- Wang A, King B, Damsky W. 674 Single-cell RNA sequencing (scRNA-seq) of sarcoidosis skin biopsies reveals key pathogenic cytokines and potential treatment targets Journal Of Investigative Dermatology 2021, 141: s117. DOI: 10.1016/j.jid.2021.02.704.
- Zhou T, Weizman O, Damsky W, McGeary M, Bosenberg M, Ring A. Abstract 2156: IL-18 pathway agonism expands intratumoral PD1+ Tcf1+ stem-like CD8+ cells and their polyfunctional effector progeny to promote anti-tumor immunity Cancer Research 2020, 80: 2156-2156. DOI: 10.1158/1538-7445.am2020-2156.
- Weizman O, Zhou T, Damsky W, McGeary M, Bosenberg M, Ring A. Abstract 3424: IL-18 immunotherapy is efficacious against checkpoint-immunotherapy refractory tumors by promoting the maturation of highly proliferative, polyfunctional NK cells Cancer Research 2020, 80: 3424-3424. DOI: 10.1158/1538-7445.am2020-3424.
- Zhou T, Damsky W, Weizman OE, McGeary MK, Hartmann KP, Rosen CE, Fischer S, Jackson R, Flavell RA, Wang J, Sanmamed MF, Bosenberg MW, Ring AM. IL-18BP is a secreted immune checkpoint and barrier to IL-18 immunotherapy Nature 2020, 583: 609-614. PMID: 32581358, PMCID: PMC7381364, DOI: 10.1038/s41586-020-2422-6.
- Damsky W, Wang A, Olamiju B, Peterson D, Galan A, King B. Treatment of severe lichen planus with the JAK inhibitor tofacitinib Journal Of Allergy And Clinical Immunology 2020, 145: 1708-1710.e2. PMID: 32018031, DOI: 10.1016/j.jaci.2020.01.031.
- Damsky W, Patel D, Garelli CJ, Garg M, Wang A, Dresser K, Deng A, Harris JE, Richmond J, King B. JAK inhibition prevents bleomycin-induced fibrosis in mice and is effective in morphea patients Journal Of Investigative Dermatology 2020, 140: 1446-1449.e4. PMID: 31954727, DOI: 10.1016/j.jid.2019.12.019.
- Krykbaeva I, Damsky W, Turner N, Perry C, Kluger H, Bosenberg M. LB1122 Myeloid targeting in combination with PD1 inhibition boosts anti-tumor immunity in melanoma Journal Of Investigative Dermatology 2019, 139: b19. DOI: 10.1016/j.jid.2019.06.089.
- Ramseier J, Charos A, Park K, Damsky W, Bosenberg M. Abstract 4622: The YUMMER.G mouse melanoma model recapitulates the heterogeneous response to immune checkpoint blockade based on patient sex 2019, 4622-4622. DOI: 10.1158/1538-7445.sabcs18-4622.
- Ramseier J, Charos A, Park K, Damsky W, Bosenberg M. Abstract 4622: The YUMMER.G mouse melanoma model recapitulates the heterogeneous response to immune checkpoint blockade based on patient sex Cancer Research 2019, 79: 4622-4622. DOI: 10.1158/1538-7445.am2019-4622.
- Damsky W, Thakral D, McGeary MK, Leventhal J, Galan A, King B. Janus kinase inhibition induces disease remission in cutaneous sarcoidosis and granuloma annulare Journal Of The American Academy Of Dermatology 2019, 82: 612-621. PMID: 31185230, PMCID: PMC7590533, DOI: 10.1016/j.jaad.2019.05.098.
- Ferreira M, Krykbaeva I, Damsky W, Kluger H, Bosenberg M. Evaluating the role of the COX2/PGE2 pathway in anti-melanoma immunity. Journal Of Clinical Oncology 2019, 37: e14114-e14114. DOI: 10.1200/jco.2019.37.15_suppl.e14114.
- Ferreira M, Damsky W, Bosenberg M. 783 Evaluating the impact of high-dose steroids on checkpoint inhibitor efficacy in a murine model of melanoma Journal Of Investigative Dermatology 2019, 139: s135. DOI: 10.1016/j.jid.2019.03.859.
- Ramseier J, Thakral D, Damsky W, Bosenberg M. 789 Immune checkpoint therapy polarizes fibroblasts into a proinflammatory state Journal Of Investigative Dermatology 2019, 139: s136. DOI: 10.1016/j.jid.2019.03.865.
- Damsky W, Thakral D, Emeagwali N, Galan A, King B. Tofacitinib Treatment and Molecular Analysis of Cutaneous Sarcoidosis New England Journal Of Medicine 2018, 379: 2540-2546. PMID: 30586518, PMCID: PMC6351852, DOI: 10.1056/nejmoa1805958.
- Turner N, Damsky W, Wang J, Meeth K, Blenman K, Bosenberg M. 1245 PD-1 blockade impedes tumor growth in the immunogenic YUMMER1.7 mouse melanoma model Journal Of Investigative Dermatology 2018, 138: s211. DOI: 10.1016/j.jid.2018.03.1260.
- Wang J, Perry CJ, Meeth K, Thakral D, Damsky W, Micevic G, Kaech S, Blenman K, Bosenberg M. UV‐induced somatic mutations elicit a functional T cell response in the YUMMER1.7 mouse melanoma model Pigment Cell & Melanoma Research 2017, 30: 428-435. PMID: 28379630, PMCID: PMC5820096, DOI: 10.1111/pcmr.12591.
- Damsky W, Wang J, Perry C, Meeth K, Kaech S, Bosenberg M. 766 Exposure to ultraviolet light enhances anti-tumor immunity and response to immunotherapy in a mouse model of melanoma Journal Of Investigative Dermatology 2017, 137: s132. DOI: 10.1016/j.jid.2017.02.791.
- Damsky W, King BA. JAK inhibitors in dermatology: The promise of a new drug class Journal Of The American Academy Of Dermatology 2017, 76: 736-744. PMID: 28139263, PMCID: PMC6035868, DOI: 10.1016/j.jaad.2016.12.005.
- Meeth K, Wang JX, Micevic G, Damsky W, Bosenberg MW. The YUMM lines: a series of congenic mouse melanoma cell lines with defined genetic alterations Pigment Cell & Melanoma Research 2016, 29: 590-597. PMID: 27287723, PMCID: PMC5331933, DOI: 10.1111/pcmr.12498.
- Bosenberg M, Meeth K, Damsky W. A comprehensive system of congenic mouse melanoma models for evaluation of immune therapies The Journal Of Immunology 2016, 196: 144.19-144.19. DOI: 10.4049/jimmunol.196.supp.144.19.
- Meeth K, Damsky W, Bosenberg M. Abstract 5141: A comprehensive system of congenic mouse melanoma models for evaluation of immune therapies 2015, 5141-5141. DOI: 10.1158/1538-7445.am2015-5141.
- Damsky W, Micevic G, Meeth K, Muthusamy V, Curley DP, Santhanakrishnan M, Erdelyi I, Platt JT, Huang L, Theodosakis N, Zaidi MR, Tighe S, Davies MA, Dankort D, McMahon M, Merlino G, Bardeesy N, Bosenberg M. mTORC1 Activation Blocks Braf V600E -Induced Growth Arrest but Is Insufficient for Melanoma Formation Cancer Cell 2015, 27: 41-56. PMID: 25584893, PMCID: PMC4295062, DOI: 10.1016/j.ccell.2014.11.014.
- Maniecki M, Etzerodt A, Damsky W, Rafique A, Gonzalez D, Dyrskjøt L, Møller H, Bosenberg M, Moestrup S. Abstract 1534: CD163-expressing macrophages constitute a distinct malignancy-promoting phenotype in melanoma facilitating tumor development, progression, and metastasis: Implications for novel anticancer therapy. Cancer Research 2013, 73: 1534-1534. DOI: 10.1158/1538-7445.am2013-1534.
- Damsky WE, Curley DP, Santhanakrishnan M, Rosenbaum LE, Platt JT, Rothberg B, Taketo MM, Dankort D, Rimm DL, McMahon M, Bosenberg M. β-Catenin Signaling Controls Metastasis in Braf-Activated Pten-Deficient Melanomas Cancer Cell 2011, 20: 741-754. PMID: 22172720, PMCID: PMC3241928, DOI: 10.1016/j.ccr.2011.10.030.
- Rosenbaum L, Damsky W, Bosenberg M. Abstract 3377: The effect of E-cadherin loss on melanoma formation and metastasis in a conditional mouse model Cancer Research 2011, 71: 3377-3377. DOI: 10.1158/1538-7445.am2011-3377.
- Maniecki M, Damsky W, Ulhøi B, Steiniche T, Ørntoft T, Dyrskjøt L, Borre M, Kjeldsen E, Bosenberg M, Møller H. Abstract 539: The expression of monocyte/macrophage-restricted scavenger receptor CD163 by malignant cells may be a consequence of cell fusion with tumor-associated macrophages: A novel target for cancer therapy Cancer Research 2011, 71: 539-539. DOI: 10.1158/1538-7445.am2011-539.
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