- Yale CardiologyYale Physicians Building800 Howard AvenueNew Haven, CT 06519
- Yale CardiologyYale Heart and Vascular Outpatient Services84 North Main StreetBranford, CT 06405
Michael Cleman, MD
Biography
Michael Cleman, MD, is an interventional cardiologist and focuses on adult structural heart disease (defects or disorders in the heart’s valves).
Dr. Cleman says he became interested in medicine after participating in independent research studies in high school and college. One program in college with a cardiologist convinced him that cardiology was the right career for him.
“It was an exciting time. Everything was moving very quickly and there was so much enthusiasm around the coronary field,” Dr. Cleman says.
He came to Yale in the early 1980s to do research in electrophysiology but ended up in the catheterization lab and performing angioplasty procedures. He became involved in the original studies and applications of what were then novel technologies—coronary stents (devices that keep the coronary arteries open to treat heart disease), rotational atherectomy(a procedure that removes plaque that clogs coronary arteries), and intravascular ultrasound.
“We were one of the first three or four people in the United States to do coronary stents, and one of the first to do rotational atherectomy,” he says.
Today, Dr. Cleman’s clinical work includes stents and diagnostic procedures, as well as TAVR (transcatheter aortic valve replacement), and mitral valve clip placements.
The best part of his job, Dr. Cleman says, is the variety—and helping to train the next generation of physicians. He also enjoys working with patients and describes himself as laid-back and approachable.
“I have a lot of experience, and I have watched how things have progressed. It’s reassuring to tell patients where things were and where they are now,” he says. “The changes have been dramatic and there are so many different treatments we can offer.”
Dr. Cleman’s clinical research interests include structural heart disease.
Titles
- Professor of Medicine (Cardiovascular Medicine)
Education & Training
- MDJohns Hopkins University (1977)
Additional Information
- AB of Internal Medicine, Cardiovascular Disease (1985)
- AB of Internal Medicine, Internal Medicine (1980)
- See C, Wang Y, Yang Y, Tirziu D, Papoutsidakis N, Francese D, Kaple R, Cleman M, Lansky A, Forrest J. Impact of sex on Transcatheter aortic valve replacement outcomes: Results of a single-center study. International Journal Of Cardiology 2023, 398: 131643. PMID: 38065329, DOI: 10.1016/j.ijcard.2023.131643.
- See C, Wang Y, Huang H, Parise H, Yang Y, Tirziu D, Francese D, Papoutsidakis N, Bader E, Kaple R, Cleman M, Lansky A, Forrest J. Impact of New‐Onset Conduction Disturbances following Transcatheter Aortic Valve Replacement on Outcomes: A Single‐Center Study. Journal Of Interventional Cardiology 2023, 2023: 5390338. PMID: 37292113, PMCID: PMC10247319, DOI: 10.1155/2023/5390338.
- Shah T, McCarthy M, Nasir I, Archer H, Ragheb E, Kluger J, Kashyap N, Paredes C, Patel P, Lu J, Kandel P, Song C, Khan M, Huang H, Haq F, Ahmad R, Howes C, Cambi B, Lancaster G, Cleman M, Dela Cruz C, Parise H, Lansky A. Colchicine and high-intensity rosuvastatin in the treatment of non-critically ill patients hospitalised with COVID-19: a randomised clinical trial. BMJ Open 2023, 13: e067910. PMID: 36828654, PMCID: PMC9971831, DOI: 10.1136/bmjopen-2022-067910.
- Outcomes of the Novel Supreme Drug-Eluting Stent in Complex Coronary Lesions: A PIONEER III SubstudyPatel K, Lansky A, Kereiakes D, Windecker S, Cristea E, Pietras C, Dressler O, Issever M, Curtis M, Bertolet B, Zidar J, Smits P, Díaz V, McLaurin B, Brogno D, Janssens L, Vrolix M, Gómez-Blázquez I, Sahul Z, Kabour A, Salido L, Cleman M, Saito S, Leon M, Baumbach A, Investigators I. Outcomes of the Novel Supreme Drug-Eluting Stent in Complex Coronary Lesions: A PIONEER III Substudy. Journal Of The Society For Cardiovascular Angiography & Interventions 2022, 1: 100004. PMID: 39130138, PMCID: PMC11308031, DOI: 10.1016/j.jscai.2021.100004.
- Arora S, Panaich SS, Patel N, Patel NJ, Lahewala S, Thakkar B, Savani C, Jhamnani S, Singh V, Patel N, Patel S, Sonani R, Patel A, Tripathi B, Deshmukh A, Chothani A, Patel J, Bhatt P, Mohamad T, Remetz MS, Curtis JP, Attaran RR, Mena CI, Schreiber T, Grines C, Cleman M, Forrest JK, Badheka AO. Impact of Glycoprotein IIb/IIIa Inhibitors Use on Outcomes After Lower Extremity Endovascular Interventions From Nationwide Inpatient Sample (2006–2011). Catheterization And Cardiovascular Interventions 2016, 88: 605-616. PMID: 26914274, DOI: 10.1002/ccd.26452.
- Deftereos S, Papoutsidakis N, Giannopoulos G, Angelidis C, Raisakis K, Bouras G, Davlouros P, Panagopoulou V, Goudevenos J, Cleman M, Lekakis J. Calcium Ions in Inherited Cardiomyopathies. Medicinal Chemistry 2015, 11: 1-1. DOI: 10.2174/1573406411666150928113018.
- Mouratoglou S, Giannakoulas G, Deftereos S, Giannopoulos G, Angelidis C, Cleman M, Vassilikos V. Intra - and Intercellular Calcium Handling in Pulmonary Arterial Hypertension. Medicinal Chemistry 2015, 11: 1-1. DOI: 10.2174/1573406411666150928113434.
- Nichols E, Kapadia S, Feldman T, Kar S, Cleman M, Buchbinder M. Updates in Mitral Valve Repair and Replacement. MD Conference Express 2015, 15: 15-18. DOI: 10.1177/1559897715591155.
- Attaran R, Cleman M. Invasive Hemodynamics. 2013, 1-7. DOI: 10.1007/978-1-4471-4528-8_1.
- Fearon W, Luna J, Samady H, Powers E, Feldman T, Dib N, Tuzcu E, Cleman M, Chou T, Cohen D, Ragosta M, Takagi A, Jeremias A, Fitzgerald P, Yeung A, Kern M, Yock P. Fractional Flow Reserve Compared With Intravascular Ultrasound Guidance for Optimizing Stent Deployment. Circulation 2001, 104: 1917-1922. PMID: 11602494, DOI: 10.1161/hc4101.097539.
- Clark D, Cleman M, Pfau S, Rollins S, Ramahi T, Mayer C, Caulin-Glaser T, Daher E, Kosiborod M, Bell L, Setaro J. Serum complement activation in congestive heart failure. American Heart Journal 2001, 141: 684-690. PMID: 11275938, DOI: 10.1067/mhj.2001.113758.
- Fitzgerald P, Oshima A, Hayase M, Metz J, Bailey S, Baim D, Cleman M, Deutsch E, Diver D, Leon M, Moses J, Oesterle S, Overlie P, Pepine C, Safian R, Shani J, Simonton C, Smalling R, Teirstein P, Zidar J, Yeung A, Kuntz R, Yock P, Investigators F. Final Results of the Can Routine Ultrasound Influence Stent Expansion (CRUISE) Study. Circulation 2000, 102: 523-530. PMID: 10920064, DOI: 10.1161/01.cir.102.5.523.
- Caulin-Glaser T, Farrell W, Pfau S, Zaret B, Bunger K, Setaro J, Brennan J, Bender J, Cleman M, Cabin H, Remetz M. Modulation of Circulating Cellular Adhesion Molecules in Postmenopausal Women With Coronary Artery Disease. Journal Of The American College Of Cardiology 1998, 31: 1555-1560. PMID: 9626834, DOI: 10.1016/s0735-1097(98)00145-4.
- Savage M, Fischman D, Rake R, Leon M, Schatz R, Penn I, Nobuyoshi M, Moses J, Hirshfeld J, Heuser R, Baim D, Cleman M, Brinker J, Gebhardt S, Goldberg S, Investigators F. Efficacy of Coronary Stenting Versus Balloon Angioplasty in Small Coronary Arteries fn1fn1This study was supported in part by a grant from Johnson & Johnson Interventional Systems, Inc., Warren, New Jersey. Journal Of The American College Of Cardiology 1998, 31: 307-311. PMID: 9462572, DOI: 10.1016/s0735-1097(97)00511-1.
- Carrozza J, Schatz R, George C, Leon M, King S, Hirshfeld J, Curry R, Ivanhoe R, Buchbinder M, Cleman M, Goldberg S, Ricci D, Popma J, Safian R, Baim D, Investigators F. Acute and Long-Term Outcome After Palmaz-Schatz Stenting: Analysis From the New Approaches To Coronary Intervention (NACI) Registry. The American Journal Of Cardiology 1997, 80: 78k-88k. PMID: 9409695, DOI: 10.1016/s0002-9149(97)00767-4.
- Brown D, George C, Steenkiste A, Cowley M, Leon M, Cleman M, Moses J, King S, Carrozza J, Holmes D, Burkhard-Meier C, Popma J, Brinker J, Buchbinder M, Investigators F. High-Speed Rotational Atherectomy of Human Coronary Stenoses: Acute and One-Year Outcomes From the New Approaches to Coronary Intervention (NACI) Registry. The American Journal Of Cardiology 1997, 80: 60k-67k. PMID: 9409693, DOI: 10.1016/s0002-9149(97)00765-0.
- Savage M, Douglas J, Fischman D, Pepine C, King S, Werner J, Bailey S, Overlie P, Fenton S, Brinker J, Leon M, Goldberg S, Heuser R, Smalling R, Safian R, Cleman M, Buchbinder M, Snead D, Rake R, Gebhardt S. Stent Placement Compared with Balloon Angioplasty for Obstructed Coronary Bypass Grafts. The New England Journal Of Medicine 1997, 337: 740-747. PMID: 9287229, DOI: 10.1056/nejm199709113371103.
- Krumholz H, Cohen D, Williams C, Baim D, Brinker J, Cabin H, Heuser R, Hirshfeld J, Leon M, Moses J, Savage M, Cleman M. Health after coronary stenting or balloon angioplasty: Results from the Stent Restenosis Study. American Heart Journal 1997, 134: 337-344. PMID: 9327686, DOI: 10.1016/s0002-8703(97)70065-6.
- Heller L, Cates C, Popma J, Deckelbaum L, Joye J, Dahlberg S, Villegas B, Arnold A, Kipperman R, Grinstead W, Balcom S, Ma Y, Cleman M, Steingart R, Leppo J. Intracoronary Doppler assessment of moderate coronary artery disease: comparison with 201Tl imaging and coronary angiography. FACTS Study Group. Circulation 1997, 96: 484-90. PMID: 9244216, DOI: 10.1161/01.cir.96.2.484.
- Mark D, Talley J, Topol E, Bowman L, Lam L, Anderson K, Jollis J, Cleman M, Lee K, Aversano T, Untereker W, Davidson-Ray L, Califf R. Economic assessment of platelet glycoprotein IIb/IIIa inhibition for prevention of ischemic complications of high-risk coronary angioplasty. EPIC Investigators. Circulation 1996, 94: 629-35. PMID: 8772681, DOI: 10.1161/01.cir.94.4.629.
- Cohen D, Krumholz H, Sukin C, Ho K, Siegrist R, Cleman M, Heuser R, Brinker J, Moses J, Savage M, Detre K, Leon M, Baim D. In-hospital and one-year economic outcomes after coronary stenting or balloon angioplasty. Results from a randomized clinical trial. Stent Restenosis Study Investigators. Circulation 1995, 92: 2480-7. PMID: 7586348, DOI: 10.1161/01.cir.92.9.2480.
- Wong S, Baim D, Schatz R, Teirstein P, King S, Curry R, Heuser R, Ellis S, Cleman M, Overlie P, Hirshfeld J, Walker C, Litvack F, Fish D, Brinker J, Buchbinder M, Goldberg S, Chuang Y, Leon M, Group P. Immediate results and late outcomes after stent implantation in saphenous vein graft lesions: The multicenter U.S. Palmaz-Schatz stent experience. Journal Of The American College Of Cardiology 1995, 26: 704-712. PMID: 7642863, DOI: 10.1016/0735-1097(95)00217-r.
- Wolfe M, Roubin G, Schweiger M, Isner J, Ferguson J, Cannon A, Cleman M, Cabin H, Leya F, Bonan R, Strony J, Adelman B, Bittl J. Length of hospital stay and complications after percutaneous transluminal coronary angioplasty. Clinical and procedural predictors. Heparin Registry Investigators. Circulation 1995, 92: 311-9. PMID: 7634443, DOI: 10.1161/01.cir.92.3.311.
- Savage M, Fischman D, Schatz R, Teirstein P, Leon M, Baim D, Ellis S, Topol E, Hirshfeld J, Cleman M, Buchbinder M, Bailey S, Heuser R, Walker C, Curry R, Gebhardt S, Rake R, Goldberg S, group F. Long-term angiographic and clinical outcome after implantation of a ballon-expandable stent in the native coronary circulation. Journal Of The American College Of Cardiology 1994, 24: 1207-1212. PMID: 7930240, DOI: 10.1016/0735-1097(94)90099-x.
- Fischman D, Leon M, Baim D, Schatz R, Savage M, Penn I, Detre K, Veltri L, Ricci D, Nobuyoshi M, Cleman M, Heuser R, Almond D, Teirstein P, Fish R, Colombo A, Brinker J, Moses J, Shaknovich A, Hirshfeld J, Bailey S, Ellis S, Rake R, Goldberg S. A Randomized Comparison of Coronary-Stent Placement and Balloon Angioplasty in the Treatment of Coronary Artery Disease. The New England Journal Of Medicine 1994, 331: 496-501. PMID: 8041414, DOI: 10.1056/nejm199408253310802.
- Ling F, Brennan J, Cleman M, Cabin H. Physiologic assessment of ostial left circumflex coronary artery disease using a doppler guidewire before and after rotational atherectomy facilitated angioplasty. Catheterization And Cardiovascular Interventions 1994, 32: 53-57. PMID: 8039221, DOI: 10.1002/ccd.1810320113.
- Ilia R, Bigham H, Brennan J, Cabin H, Cleman M, Remetz M. Predictors of Coronary Dissection following Percutaneous Transluminal Coronary Balloon Angioplasty. Cardiology 1994, 85: 229-234. PMID: 7987880, DOI: 10.1159/000176680.
- Fischman D, Savage M, Leon M, Schatz R, Ellis S, Cleman M, Hirshfeld J, Teirstein P, Bailey S, Walker C, Goldberg S. Fate of lesion-related side branches after coronary artery stenting. Journal Of The American College Of Cardiology 1993, 22: 1641-1646. PMID: 8227832, DOI: 10.1016/0735-1097(93)90589-s.
- Haronian H, Remetz M, Sinusas A, Baron J, Miller H, Cleman M, Zaret B, Wackers F. Myocardial risk area defined by technetium-99m sestamibi imaging during percutaneous transluminal coronary angioplasty: Comparison with coronary angiography. Journal Of The American College Of Cardiology 1993, 22: 1033-1043. PMID: 8409038, DOI: 10.1016/0735-1097(93)90413-u.
- Ilia R, Kolanski D, Setaro J, Brennan J, Cabin H, Cleman M, Remetz M. Clinical and Angiographic Determinants of Initial Percutaneous Transluminal Coronary Angioplasty Success. Angiology 1993, 44: 677-682. PMID: 8357092, DOI: 10.1177/000331979304400901.
- Ilia R, Cabin H, McConnell S, Cleman M, Remetz M. Coronary angioplasty with gradual versus rapid balloon inflation: Initial results and complications. Catheterization And Cardiovascular Interventions 1993, 29: 199-202. PMID: 8402842, DOI: 10.1002/ccd.1810290305.
- Ellis S, Savage M, Fischman D, Baim D, Leon M, Goldberg S, Hirshfeld J, Cleman M, Teirstein P, Walker C. Restenosis after placement of Palmaz-Schatz stents in native coronary arteries. Initial results of a multicenter experience. Circulation 1992, 86: 1836-1844. PMID: 1451256, DOI: 10.1161/01.cir.86.6.1836.
- Characteristics of cigarette smokers versus nonsmokers in patients referred for coronary angioplastyIlia R, Brennan J, Cabin H, Cleman M, Remetz M. Characteristics of cigarette smokers versus nonsmokers in patients referred for coronary angioplasty. Coronary Artery Disease 1992, 3: 859-862. DOI: 10.1097/00019501-199209000-00013.
- Setaro J, Cleman M, Remetz M. The Right Ventricle in Disorders Causing Pulmonary Venous Hypertension. Cardiology Clinics 1992, 10: 165-183. PMID: 1739957, DOI: 10.1016/s0733-8651(18)30261-3.
- Ilia R, Kolansky D, Setaro J, Brennan J, Cabin H, Cleman M, Remetz M. Percutaneous Transluminal Coronary Angioplasty in Unstable and Stable Angina pectoris: A Comparison of Immediate Success and Complications. Cardiology 1992, 81: 245-250. PMID: 1301250, DOI: 10.1159/000175811.
- Fischman D, Savage M, Leon M, Schatz R, Ellis S, Cleman M, Teirstein P, Walker C, Bailey S, Hirshfeld J, Goldberg S. Effect of intracoronary stenting on intimal dissection after balloon angioplasty: Results of quantitative and qualitative coronary analysis. Journal Of The American College Of Cardiology 1991, 18: 1445-1451. PMID: 1939944, DOI: 10.1016/0735-1097(91)90673-w.
- Kayden D, Remetz M, Cabin H, Deckelbaum L, Cleman M, Wackers F, Zaret B. Validation of continuous radionuclide left ventricular functioning monitoring in detecting silent myocardial ischemia during balloon angioplasty of the left anterior descending coronary artery. The American Journal Of Cardiology 1991, 67: 1339-1343. PMID: 2042565, DOI: 10.1016/0002-9149(91)90462-t.
- Schatz R, Goldberg S, Leon M, Baim D, Hirshfeld J, Cleman M, Ellis S, Topol E. Clinical experience with the Palmaz-Schatz coronary stent. Journal Of The American College Of Cardiology 1991, 17: 155-159. PMID: 2016473, DOI: 10.1016/0735-1097(91)90952-6.
- Schatz R, Baim D, Leon M, Ellis S, Goldberg S, Hirshfeld J, Cleman M, Cabin H, Walker C, Stagg J. Clinical experience with the Palmaz-Schatz coronary stent. Initial results of a multicenter study. Circulation 1991, 83: 148-161. PMID: 1984878, DOI: 10.1161/01.cir.83.1.148.
- Lasala J, Remetz M, Cleman M, Cabin H. Inadvertent “atherectomy” during ostial right coronary artery angioplasty. American Heart Journal 1990, 120: 423-424. PMID: 2382619, DOI: 10.1016/0002-8703(90)90089-g.
- Kent K, Cleman M, Cowley M, Forman M, Jaffe C, Kaplan M, King S, Krucoff M, Lassar T, McAuley B, Smith R, Wisdom C, Wohlgelernter D. Reduction of myocardial ischemia during percutaneous transluminal coronary angioplasty with oxygenated Fluosol®11Fluosol® (20% Intravascular Perfluorochemical Emulsion) is a registered trademark of The Green Cross Corporation, Osaka, Japan. The American Journal Of Cardiology 1990, 66: 279-284. PMID: 2195864, DOI: 10.1016/0002-9149(90)90836-p.
- Young L, Jaffe C, Revkin J, McNulty P, Cleman M. Metabolic and functional effects of perfluorocarbon distal perfusion during coronary angioplasty. The American Journal Of Cardiology 1990, 65: 986-990. PMID: 2327360, DOI: 10.1016/0002-9149(90)91001-m.
- Cleman M, Wohlgelernter D, Cabin H, Remetz M, McConnell S, Jaffe C. Myocardial dysfunction during percutaneous transluminal coronary angioplasty. Circulation 1990, 81: iv14-9. PMID: 2306846.
- LaVeau P, Remetz M, Cabin H, Hennecken J, McConnell S, Rosen R, Cleman M. Predictors of success in percutaneous transluminal coronary angioplasty of chronic total occlusions. The American Journal Of Cardiology 1989, 64: 1264-1269. PMID: 2589190, DOI: 10.1016/0002-9149(89)90565-1.
- Remetz M, Cleman M, Cabin H. Pulmonary and Pleural Complications of Cardiac Disease. Clinics In Chest Medicine 1989, 10: 545-592. PMID: 2689066, DOI: 10.1016/s0272-5231(21)00655-9.
- Cabin H, Cleman M. Update on Percutaneous Transluminal Coronary Angioplasty. Cardiology Clinics 1988, 6: 321-328. PMID: 2977570, DOI: 10.1016/s0733-8651(18)30480-6.
- Cleman M, Cabin H. Preface. Cardiology Clinics 1988, 6: vii. DOI: 10.1016/s0733-8651(18)30479-x.
- Lasala J, Cleman M. Myocardial Protection During Percutaneous Transluminal Coronary Angioplasty. Cardiology Clinics 1988, 6: 329-343. PMID: 2977571, DOI: 10.1016/s0733-8651(18)30481-8.
- Jaffe C, Wohlgelernter D, Cabin H, Bowman L, Deckelbaum L, Remetz M, Cleman M. Preservation of left ventricular ejection fraction during percutaneous transluminal coronary angioplasty by distal transcatheter coronary perfusion of oxygenated fluosol DA 20%. American Heart Journal 1988, 115: 1156-1164. PMID: 2967624, DOI: 10.1016/0002-8703(88)90002-6.
- Bowman L, Cleman M, Cabin H, Zaret B, Jaffe C. Dynamics of early and late left ventricular filling determined by Doppler two-dimensional echocardiography during percutaneous transluminal coronary angioplasty. The American Journal Of Cardiology 1988, 61: 541-545. PMID: 2964191, DOI: 10.1016/0002-9149(88)90761-8.
- Remetz M, Cleman M. Percutaneous Transluminal Coronary Angioplasty During Acute Myocardial Infarction. Cardiology Clinics 1988, 6: 139-152. PMID: 2971441, DOI: 10.1016/s0733-8651(18)30507-1.
- Wohlgelernter D, Jaffe C, Cabin H, Yeatman L, Cleman M. Silent ischemia during coronary occlusion produced by balloon inflation: Relation to regional myocardial dysfunction. Journal Of The American College Of Cardiology 1987, 10: 491-498. PMID: 2957410, DOI: 10.1016/s0735-1097(87)80189-4.
- Klevan T, Deckelbaum L, Wohlgelernter D, Cleman M. Coronary vasospasm culminating in thromboels and infarction following “successful” coronary angioplasty. American Heart Journal 1987, 113: 1220-1222. PMID: 2953222, DOI: 10.1016/0002-8703(87)90937-9.
- Wohlgelernter D, Cleman M, Highman H, Zaret B. Percutaneous transluminal coronary angioplasty of the “culprit lesion” for management of unstable angina pectoris in patients with multivessel coronary artery disease. The American Journal Of Cardiology 1986, 58: 460-464. PMID: 2944366, DOI: 10.1016/0002-9149(86)90015-9.
- Cleman M, Jaffee C, Wohlgelernter D. Prevention of ischemia during percutaneous transluminal coronary angioplasty by transcatheter infusion of oxygenated Fluosol DA 20%. Circulation 1986, 74: 555-562. PMID: 2943533, DOI: 10.1161/01.cir.74.3.555.
- Wohlgelernter D, Cleman M, Highman H, Fetterman R, Duncan J, Zaret B, Jaffe C. Regional myocardial dysfunction during coronary angioplasty: Evaluation by two-dimensional echocardiography and 12 lead electrocardiography. Journal Of The American College Of Cardiology 1986, 7: 1245-1254. PMID: 2940283, DOI: 10.1016/s0735-1097(86)80143-7.
- Jaffe C, Wohlgelernter D, Highman H, Cleman M. Oxygenated fluosol DA-20% distal infusion during coronary angioplasty protects myocardial function. Progress In Clinical And Biological Research 1986, 211: 21-7. PMID: 2938192.
- Breisblatt W, Berger R, Cabin H, Cleman M, Cerqueira M, Neumann R, Ezekowitz M, Hashim S, Berger H. Unsuspected left ventricular pseudoaneurysm. American Journal Of Roentgenology 1984, 142: 680-2. PMID: 6608221, DOI: 10.2214/ajr.142.4.680.
- Francis C, Cleman M, Berger H, Davies R, Giles R, Black H, Vita N, Zito R, Zaret B. Left ventricular systolic performance during upright bicycle exercise in patients with essential hypertension. The American Journal Of Medicine 1983, 75: 40-46. PMID: 6226194, DOI: 10.1016/0002-9343(83)90116-x.
- Yale CardiologyYale Physicians Building800 Howard AvenueNew Haven, CT 06519
- Yale CardiologyYale Heart and Vascular Outpatient Services84 North Main StreetBranford, CT 06405
Biography
Michael Cleman, MD, is an interventional cardiologist and focuses on adult structural heart disease (defects or disorders in the heart’s valves).
Dr. Cleman says he became interested in medicine after participating in independent research studies in high school and college. One program in college with a cardiologist convinced him that cardiology was the right career for him.
“It was an exciting time. Everything was moving very quickly and there was so much enthusiasm around the coronary field,” Dr. Cleman says.
He came to Yale in the early 1980s to do research in electrophysiology but ended up in the catheterization lab and performing angioplasty procedures. He became involved in the original studies and applications of what were then novel technologies—coronary stents (devices that keep the coronary arteries open to treat heart disease), rotational atherectomy(a procedure that removes plaque that clogs coronary arteries), and intravascular ultrasound.
“We were one of the first three or four people in the United States to do coronary stents, and one of the first to do rotational atherectomy,” he says.
Today, Dr. Cleman’s clinical work includes stents and diagnostic procedures, as well as TAVR (transcatheter aortic valve replacement), and mitral valve clip placements.
The best part of his job, Dr. Cleman says, is the variety—and helping to train the next generation of physicians. He also enjoys working with patients and describes himself as laid-back and approachable.
“I have a lot of experience, and I have watched how things have progressed. It’s reassuring to tell patients where things were and where they are now,” he says. “The changes have been dramatic and there are so many different treatments we can offer.”
Dr. Cleman’s clinical research interests include structural heart disease.
Titles
- Professor of Medicine (Cardiovascular Medicine)
Education & Training
- MDJohns Hopkins University (1977)
Additional Information
- AB of Internal Medicine, Cardiovascular Disease (1985)
- AB of Internal Medicine, Internal Medicine (1980)
- See C, Wang Y, Yang Y, Tirziu D, Papoutsidakis N, Francese D, Kaple R, Cleman M, Lansky A, Forrest J. Impact of sex on Transcatheter aortic valve replacement outcomes: Results of a single-center study. International Journal Of Cardiology 2023, 398: 131643. PMID: 38065329, DOI: 10.1016/j.ijcard.2023.131643.
- See C, Wang Y, Huang H, Parise H, Yang Y, Tirziu D, Francese D, Papoutsidakis N, Bader E, Kaple R, Cleman M, Lansky A, Forrest J. Impact of New‐Onset Conduction Disturbances following Transcatheter Aortic Valve Replacement on Outcomes: A Single‐Center Study. Journal Of Interventional Cardiology 2023, 2023: 5390338. PMID: 37292113, PMCID: PMC10247319, DOI: 10.1155/2023/5390338.
- Shah T, McCarthy M, Nasir I, Archer H, Ragheb E, Kluger J, Kashyap N, Paredes C, Patel P, Lu J, Kandel P, Song C, Khan M, Huang H, Haq F, Ahmad R, Howes C, Cambi B, Lancaster G, Cleman M, Dela Cruz C, Parise H, Lansky A. Colchicine and high-intensity rosuvastatin in the treatment of non-critically ill patients hospitalised with COVID-19: a randomised clinical trial. BMJ Open 2023, 13: e067910. PMID: 36828654, PMCID: PMC9971831, DOI: 10.1136/bmjopen-2022-067910.
- Outcomes of the Novel Supreme Drug-Eluting Stent in Complex Coronary Lesions: A PIONEER III SubstudyPatel K, Lansky A, Kereiakes D, Windecker S, Cristea E, Pietras C, Dressler O, Issever M, Curtis M, Bertolet B, Zidar J, Smits P, Díaz V, McLaurin B, Brogno D, Janssens L, Vrolix M, Gómez-Blázquez I, Sahul Z, Kabour A, Salido L, Cleman M, Saito S, Leon M, Baumbach A, Investigators I. Outcomes of the Novel Supreme Drug-Eluting Stent in Complex Coronary Lesions: A PIONEER III Substudy. Journal Of The Society For Cardiovascular Angiography & Interventions 2022, 1: 100004. PMID: 39130138, PMCID: PMC11308031, DOI: 10.1016/j.jscai.2021.100004.
- Arora S, Panaich SS, Patel N, Patel NJ, Lahewala S, Thakkar B, Savani C, Jhamnani S, Singh V, Patel N, Patel S, Sonani R, Patel A, Tripathi B, Deshmukh A, Chothani A, Patel J, Bhatt P, Mohamad T, Remetz MS, Curtis JP, Attaran RR, Mena CI, Schreiber T, Grines C, Cleman M, Forrest JK, Badheka AO. Impact of Glycoprotein IIb/IIIa Inhibitors Use on Outcomes After Lower Extremity Endovascular Interventions From Nationwide Inpatient Sample (2006–2011). Catheterization And Cardiovascular Interventions 2016, 88: 605-616. PMID: 26914274, DOI: 10.1002/ccd.26452.
- Deftereos S, Papoutsidakis N, Giannopoulos G, Angelidis C, Raisakis K, Bouras G, Davlouros P, Panagopoulou V, Goudevenos J, Cleman M, Lekakis J. Calcium Ions in Inherited Cardiomyopathies. Medicinal Chemistry 2015, 11: 1-1. DOI: 10.2174/1573406411666150928113018.
- Mouratoglou S, Giannakoulas G, Deftereos S, Giannopoulos G, Angelidis C, Cleman M, Vassilikos V. Intra - and Intercellular Calcium Handling in Pulmonary Arterial Hypertension. Medicinal Chemistry 2015, 11: 1-1. DOI: 10.2174/1573406411666150928113434.
- Nichols E, Kapadia S, Feldman T, Kar S, Cleman M, Buchbinder M. Updates in Mitral Valve Repair and Replacement. MD Conference Express 2015, 15: 15-18. DOI: 10.1177/1559897715591155.
- Attaran R, Cleman M. Invasive Hemodynamics. 2013, 1-7. DOI: 10.1007/978-1-4471-4528-8_1.
- Fearon W, Luna J, Samady H, Powers E, Feldman T, Dib N, Tuzcu E, Cleman M, Chou T, Cohen D, Ragosta M, Takagi A, Jeremias A, Fitzgerald P, Yeung A, Kern M, Yock P. Fractional Flow Reserve Compared With Intravascular Ultrasound Guidance for Optimizing Stent Deployment. Circulation 2001, 104: 1917-1922. PMID: 11602494, DOI: 10.1161/hc4101.097539.
- Clark D, Cleman M, Pfau S, Rollins S, Ramahi T, Mayer C, Caulin-Glaser T, Daher E, Kosiborod M, Bell L, Setaro J. Serum complement activation in congestive heart failure. American Heart Journal 2001, 141: 684-690. PMID: 11275938, DOI: 10.1067/mhj.2001.113758.
- Fitzgerald P, Oshima A, Hayase M, Metz J, Bailey S, Baim D, Cleman M, Deutsch E, Diver D, Leon M, Moses J, Oesterle S, Overlie P, Pepine C, Safian R, Shani J, Simonton C, Smalling R, Teirstein P, Zidar J, Yeung A, Kuntz R, Yock P, Investigators F. Final Results of the Can Routine Ultrasound Influence Stent Expansion (CRUISE) Study. Circulation 2000, 102: 523-530. PMID: 10920064, DOI: 10.1161/01.cir.102.5.523.
- Caulin-Glaser T, Farrell W, Pfau S, Zaret B, Bunger K, Setaro J, Brennan J, Bender J, Cleman M, Cabin H, Remetz M. Modulation of Circulating Cellular Adhesion Molecules in Postmenopausal Women With Coronary Artery Disease. Journal Of The American College Of Cardiology 1998, 31: 1555-1560. PMID: 9626834, DOI: 10.1016/s0735-1097(98)00145-4.
- Savage M, Fischman D, Rake R, Leon M, Schatz R, Penn I, Nobuyoshi M, Moses J, Hirshfeld J, Heuser R, Baim D, Cleman M, Brinker J, Gebhardt S, Goldberg S, Investigators F. Efficacy of Coronary Stenting Versus Balloon Angioplasty in Small Coronary Arteries fn1fn1This study was supported in part by a grant from Johnson & Johnson Interventional Systems, Inc., Warren, New Jersey. Journal Of The American College Of Cardiology 1998, 31: 307-311. PMID: 9462572, DOI: 10.1016/s0735-1097(97)00511-1.
- Carrozza J, Schatz R, George C, Leon M, King S, Hirshfeld J, Curry R, Ivanhoe R, Buchbinder M, Cleman M, Goldberg S, Ricci D, Popma J, Safian R, Baim D, Investigators F. Acute and Long-Term Outcome After Palmaz-Schatz Stenting: Analysis From the New Approaches To Coronary Intervention (NACI) Registry. The American Journal Of Cardiology 1997, 80: 78k-88k. PMID: 9409695, DOI: 10.1016/s0002-9149(97)00767-4.
- Brown D, George C, Steenkiste A, Cowley M, Leon M, Cleman M, Moses J, King S, Carrozza J, Holmes D, Burkhard-Meier C, Popma J, Brinker J, Buchbinder M, Investigators F. High-Speed Rotational Atherectomy of Human Coronary Stenoses: Acute and One-Year Outcomes From the New Approaches to Coronary Intervention (NACI) Registry. The American Journal Of Cardiology 1997, 80: 60k-67k. PMID: 9409693, DOI: 10.1016/s0002-9149(97)00765-0.
- Savage M, Douglas J, Fischman D, Pepine C, King S, Werner J, Bailey S, Overlie P, Fenton S, Brinker J, Leon M, Goldberg S, Heuser R, Smalling R, Safian R, Cleman M, Buchbinder M, Snead D, Rake R, Gebhardt S. Stent Placement Compared with Balloon Angioplasty for Obstructed Coronary Bypass Grafts. The New England Journal Of Medicine 1997, 337: 740-747. PMID: 9287229, DOI: 10.1056/nejm199709113371103.
- Krumholz H, Cohen D, Williams C, Baim D, Brinker J, Cabin H, Heuser R, Hirshfeld J, Leon M, Moses J, Savage M, Cleman M. Health after coronary stenting or balloon angioplasty: Results from the Stent Restenosis Study. American Heart Journal 1997, 134: 337-344. PMID: 9327686, DOI: 10.1016/s0002-8703(97)70065-6.
- Heller L, Cates C, Popma J, Deckelbaum L, Joye J, Dahlberg S, Villegas B, Arnold A, Kipperman R, Grinstead W, Balcom S, Ma Y, Cleman M, Steingart R, Leppo J. Intracoronary Doppler assessment of moderate coronary artery disease: comparison with 201Tl imaging and coronary angiography. FACTS Study Group. Circulation 1997, 96: 484-90. PMID: 9244216, DOI: 10.1161/01.cir.96.2.484.
- Mark D, Talley J, Topol E, Bowman L, Lam L, Anderson K, Jollis J, Cleman M, Lee K, Aversano T, Untereker W, Davidson-Ray L, Califf R. Economic assessment of platelet glycoprotein IIb/IIIa inhibition for prevention of ischemic complications of high-risk coronary angioplasty. EPIC Investigators. Circulation 1996, 94: 629-35. PMID: 8772681, DOI: 10.1161/01.cir.94.4.629.
- Cohen D, Krumholz H, Sukin C, Ho K, Siegrist R, Cleman M, Heuser R, Brinker J, Moses J, Savage M, Detre K, Leon M, Baim D. In-hospital and one-year economic outcomes after coronary stenting or balloon angioplasty. Results from a randomized clinical trial. Stent Restenosis Study Investigators. Circulation 1995, 92: 2480-7. PMID: 7586348, DOI: 10.1161/01.cir.92.9.2480.
- Wong S, Baim D, Schatz R, Teirstein P, King S, Curry R, Heuser R, Ellis S, Cleman M, Overlie P, Hirshfeld J, Walker C, Litvack F, Fish D, Brinker J, Buchbinder M, Goldberg S, Chuang Y, Leon M, Group P. Immediate results and late outcomes after stent implantation in saphenous vein graft lesions: The multicenter U.S. Palmaz-Schatz stent experience. Journal Of The American College Of Cardiology 1995, 26: 704-712. PMID: 7642863, DOI: 10.1016/0735-1097(95)00217-r.
- Wolfe M, Roubin G, Schweiger M, Isner J, Ferguson J, Cannon A, Cleman M, Cabin H, Leya F, Bonan R, Strony J, Adelman B, Bittl J. Length of hospital stay and complications after percutaneous transluminal coronary angioplasty. Clinical and procedural predictors. Heparin Registry Investigators. Circulation 1995, 92: 311-9. PMID: 7634443, DOI: 10.1161/01.cir.92.3.311.
- Savage M, Fischman D, Schatz R, Teirstein P, Leon M, Baim D, Ellis S, Topol E, Hirshfeld J, Cleman M, Buchbinder M, Bailey S, Heuser R, Walker C, Curry R, Gebhardt S, Rake R, Goldberg S, group F. Long-term angiographic and clinical outcome after implantation of a ballon-expandable stent in the native coronary circulation. Journal Of The American College Of Cardiology 1994, 24: 1207-1212. PMID: 7930240, DOI: 10.1016/0735-1097(94)90099-x.
- Fischman D, Leon M, Baim D, Schatz R, Savage M, Penn I, Detre K, Veltri L, Ricci D, Nobuyoshi M, Cleman M, Heuser R, Almond D, Teirstein P, Fish R, Colombo A, Brinker J, Moses J, Shaknovich A, Hirshfeld J, Bailey S, Ellis S, Rake R, Goldberg S. A Randomized Comparison of Coronary-Stent Placement and Balloon Angioplasty in the Treatment of Coronary Artery Disease. The New England Journal Of Medicine 1994, 331: 496-501. PMID: 8041414, DOI: 10.1056/nejm199408253310802.
- Ling F, Brennan J, Cleman M, Cabin H. Physiologic assessment of ostial left circumflex coronary artery disease using a doppler guidewire before and after rotational atherectomy facilitated angioplasty. Catheterization And Cardiovascular Interventions 1994, 32: 53-57. PMID: 8039221, DOI: 10.1002/ccd.1810320113.
- Ilia R, Bigham H, Brennan J, Cabin H, Cleman M, Remetz M. Predictors of Coronary Dissection following Percutaneous Transluminal Coronary Balloon Angioplasty. Cardiology 1994, 85: 229-234. PMID: 7987880, DOI: 10.1159/000176680.
- Fischman D, Savage M, Leon M, Schatz R, Ellis S, Cleman M, Hirshfeld J, Teirstein P, Bailey S, Walker C, Goldberg S. Fate of lesion-related side branches after coronary artery stenting. Journal Of The American College Of Cardiology 1993, 22: 1641-1646. PMID: 8227832, DOI: 10.1016/0735-1097(93)90589-s.
- Haronian H, Remetz M, Sinusas A, Baron J, Miller H, Cleman M, Zaret B, Wackers F. Myocardial risk area defined by technetium-99m sestamibi imaging during percutaneous transluminal coronary angioplasty: Comparison with coronary angiography. Journal Of The American College Of Cardiology 1993, 22: 1033-1043. PMID: 8409038, DOI: 10.1016/0735-1097(93)90413-u.
- Ilia R, Kolanski D, Setaro J, Brennan J, Cabin H, Cleman M, Remetz M. Clinical and Angiographic Determinants of Initial Percutaneous Transluminal Coronary Angioplasty Success. Angiology 1993, 44: 677-682. PMID: 8357092, DOI: 10.1177/000331979304400901.
- Ilia R, Cabin H, McConnell S, Cleman M, Remetz M. Coronary angioplasty with gradual versus rapid balloon inflation: Initial results and complications. Catheterization And Cardiovascular Interventions 1993, 29: 199-202. PMID: 8402842, DOI: 10.1002/ccd.1810290305.
- Ellis S, Savage M, Fischman D, Baim D, Leon M, Goldberg S, Hirshfeld J, Cleman M, Teirstein P, Walker C. Restenosis after placement of Palmaz-Schatz stents in native coronary arteries. Initial results of a multicenter experience. Circulation 1992, 86: 1836-1844. PMID: 1451256, DOI: 10.1161/01.cir.86.6.1836.
- Characteristics of cigarette smokers versus nonsmokers in patients referred for coronary angioplastyIlia R, Brennan J, Cabin H, Cleman M, Remetz M. Characteristics of cigarette smokers versus nonsmokers in patients referred for coronary angioplasty. Coronary Artery Disease 1992, 3: 859-862. DOI: 10.1097/00019501-199209000-00013.
- Setaro J, Cleman M, Remetz M. The Right Ventricle in Disorders Causing Pulmonary Venous Hypertension. Cardiology Clinics 1992, 10: 165-183. PMID: 1739957, DOI: 10.1016/s0733-8651(18)30261-3.
- Ilia R, Kolansky D, Setaro J, Brennan J, Cabin H, Cleman M, Remetz M. Percutaneous Transluminal Coronary Angioplasty in Unstable and Stable Angina pectoris: A Comparison of Immediate Success and Complications. Cardiology 1992, 81: 245-250. PMID: 1301250, DOI: 10.1159/000175811.
- Fischman D, Savage M, Leon M, Schatz R, Ellis S, Cleman M, Teirstein P, Walker C, Bailey S, Hirshfeld J, Goldberg S. Effect of intracoronary stenting on intimal dissection after balloon angioplasty: Results of quantitative and qualitative coronary analysis. Journal Of The American College Of Cardiology 1991, 18: 1445-1451. PMID: 1939944, DOI: 10.1016/0735-1097(91)90673-w.
- Kayden D, Remetz M, Cabin H, Deckelbaum L, Cleman M, Wackers F, Zaret B. Validation of continuous radionuclide left ventricular functioning monitoring in detecting silent myocardial ischemia during balloon angioplasty of the left anterior descending coronary artery. The American Journal Of Cardiology 1991, 67: 1339-1343. PMID: 2042565, DOI: 10.1016/0002-9149(91)90462-t.
- Schatz R, Goldberg S, Leon M, Baim D, Hirshfeld J, Cleman M, Ellis S, Topol E. Clinical experience with the Palmaz-Schatz coronary stent. Journal Of The American College Of Cardiology 1991, 17: 155-159. PMID: 2016473, DOI: 10.1016/0735-1097(91)90952-6.
- Schatz R, Baim D, Leon M, Ellis S, Goldberg S, Hirshfeld J, Cleman M, Cabin H, Walker C, Stagg J. Clinical experience with the Palmaz-Schatz coronary stent. Initial results of a multicenter study. Circulation 1991, 83: 148-161. PMID: 1984878, DOI: 10.1161/01.cir.83.1.148.
- Lasala J, Remetz M, Cleman M, Cabin H. Inadvertent “atherectomy” during ostial right coronary artery angioplasty. American Heart Journal 1990, 120: 423-424. PMID: 2382619, DOI: 10.1016/0002-8703(90)90089-g.
- Kent K, Cleman M, Cowley M, Forman M, Jaffe C, Kaplan M, King S, Krucoff M, Lassar T, McAuley B, Smith R, Wisdom C, Wohlgelernter D. Reduction of myocardial ischemia during percutaneous transluminal coronary angioplasty with oxygenated Fluosol®11Fluosol® (20% Intravascular Perfluorochemical Emulsion) is a registered trademark of The Green Cross Corporation, Osaka, Japan. The American Journal Of Cardiology 1990, 66: 279-284. PMID: 2195864, DOI: 10.1016/0002-9149(90)90836-p.
- Young L, Jaffe C, Revkin J, McNulty P, Cleman M. Metabolic and functional effects of perfluorocarbon distal perfusion during coronary angioplasty. The American Journal Of Cardiology 1990, 65: 986-990. PMID: 2327360, DOI: 10.1016/0002-9149(90)91001-m.
- Cleman M, Wohlgelernter D, Cabin H, Remetz M, McConnell S, Jaffe C. Myocardial dysfunction during percutaneous transluminal coronary angioplasty. Circulation 1990, 81: iv14-9. PMID: 2306846.
- LaVeau P, Remetz M, Cabin H, Hennecken J, McConnell S, Rosen R, Cleman M. Predictors of success in percutaneous transluminal coronary angioplasty of chronic total occlusions. The American Journal Of Cardiology 1989, 64: 1264-1269. PMID: 2589190, DOI: 10.1016/0002-9149(89)90565-1.
- Remetz M, Cleman M, Cabin H. Pulmonary and Pleural Complications of Cardiac Disease. Clinics In Chest Medicine 1989, 10: 545-592. PMID: 2689066, DOI: 10.1016/s0272-5231(21)00655-9.
- Cabin H, Cleman M. Update on Percutaneous Transluminal Coronary Angioplasty. Cardiology Clinics 1988, 6: 321-328. PMID: 2977570, DOI: 10.1016/s0733-8651(18)30480-6.
- Cleman M, Cabin H. Preface. Cardiology Clinics 1988, 6: vii. DOI: 10.1016/s0733-8651(18)30479-x.
- Lasala J, Cleman M. Myocardial Protection During Percutaneous Transluminal Coronary Angioplasty. Cardiology Clinics 1988, 6: 329-343. PMID: 2977571, DOI: 10.1016/s0733-8651(18)30481-8.
- Jaffe C, Wohlgelernter D, Cabin H, Bowman L, Deckelbaum L, Remetz M, Cleman M. Preservation of left ventricular ejection fraction during percutaneous transluminal coronary angioplasty by distal transcatheter coronary perfusion of oxygenated fluosol DA 20%. American Heart Journal 1988, 115: 1156-1164. PMID: 2967624, DOI: 10.1016/0002-8703(88)90002-6.
- Bowman L, Cleman M, Cabin H, Zaret B, Jaffe C. Dynamics of early and late left ventricular filling determined by Doppler two-dimensional echocardiography during percutaneous transluminal coronary angioplasty. The American Journal Of Cardiology 1988, 61: 541-545. PMID: 2964191, DOI: 10.1016/0002-9149(88)90761-8.
- Remetz M, Cleman M. Percutaneous Transluminal Coronary Angioplasty During Acute Myocardial Infarction. Cardiology Clinics 1988, 6: 139-152. PMID: 2971441, DOI: 10.1016/s0733-8651(18)30507-1.
- Wohlgelernter D, Jaffe C, Cabin H, Yeatman L, Cleman M. Silent ischemia during coronary occlusion produced by balloon inflation: Relation to regional myocardial dysfunction. Journal Of The American College Of Cardiology 1987, 10: 491-498. PMID: 2957410, DOI: 10.1016/s0735-1097(87)80189-4.
- Klevan T, Deckelbaum L, Wohlgelernter D, Cleman M. Coronary vasospasm culminating in thromboels and infarction following “successful” coronary angioplasty. American Heart Journal 1987, 113: 1220-1222. PMID: 2953222, DOI: 10.1016/0002-8703(87)90937-9.
- Wohlgelernter D, Cleman M, Highman H, Zaret B. Percutaneous transluminal coronary angioplasty of the “culprit lesion” for management of unstable angina pectoris in patients with multivessel coronary artery disease. The American Journal Of Cardiology 1986, 58: 460-464. PMID: 2944366, DOI: 10.1016/0002-9149(86)90015-9.
- Cleman M, Jaffee C, Wohlgelernter D. Prevention of ischemia during percutaneous transluminal coronary angioplasty by transcatheter infusion of oxygenated Fluosol DA 20%. Circulation 1986, 74: 555-562. PMID: 2943533, DOI: 10.1161/01.cir.74.3.555.
- Wohlgelernter D, Cleman M, Highman H, Fetterman R, Duncan J, Zaret B, Jaffe C. Regional myocardial dysfunction during coronary angioplasty: Evaluation by two-dimensional echocardiography and 12 lead electrocardiography. Journal Of The American College Of Cardiology 1986, 7: 1245-1254. PMID: 2940283, DOI: 10.1016/s0735-1097(86)80143-7.
- Jaffe C, Wohlgelernter D, Highman H, Cleman M. Oxygenated fluosol DA-20% distal infusion during coronary angioplasty protects myocardial function. Progress In Clinical And Biological Research 1986, 211: 21-7. PMID: 2938192.
- Breisblatt W, Berger R, Cabin H, Cleman M, Cerqueira M, Neumann R, Ezekowitz M, Hashim S, Berger H. Unsuspected left ventricular pseudoaneurysm. American Journal Of Roentgenology 1984, 142: 680-2. PMID: 6608221, DOI: 10.2214/ajr.142.4.680.
- Francis C, Cleman M, Berger H, Davies R, Giles R, Black H, Vita N, Zito R, Zaret B. Left ventricular systolic performance during upright bicycle exercise in patients with essential hypertension. The American Journal Of Medicine 1983, 75: 40-46. PMID: 6226194, DOI: 10.1016/0002-9343(83)90116-x.
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- Yale CardiologyYale Heart and Vascular Outpatient Services84 North Main StreetBranford, CT 06405