- Pediatric Specialty CenterSmilow Cancer Hospital at Yale New Haven35 Park Street, Wing North Pavillion Fl 7New Haven, CT 06511
- Pediatric Specialty CenterTrumbull Pediatric Specialty Center5520 Park Avenue, Ste 600Trumbull, CT 06611
- Pediatric Specialty CenterOld Saybrook Medical Center633 Middlesex Turnpike, Ste 110Old Saybrook, CT 06475
Lakshmanan Krishnamurti, MD
Biography
Lakshmanan Krishnamurti, MD, is chief of Pediatric Hematology and Oncology and specializes in bone marrow transplant and treating sickle cell disease and other inherited red blood cell disorders.
Dr. Krishnamurti says he decided in second grade that he would become a physician.
“I read something about doctors helping people and I just knew that was what I was going to do. Nobody ever dissuaded me,” he says.
Pediatrics, he adds, was an obvious fit because of the joy he finds working with children.
“Children have such an original view of the world. They aren’t weighed down by burdens, and they see life as an unending horizon in front of them. They are confident in their perspective and they are unfiltered,” he says. “You can look at a child and know if they are doing well or not.”
Still, it takes a special set of communication skills to draw them out, Dr. Krishnamurti says. “Children often have concrete anxieties and fears. They aren’t worried about global warming, but if something is going to hurt and if you are someone they can trust,” he says. “They might not have the eloquence to say that, but you can read their body language.”
To connect with children and their families, Dr. Krishnamurti says he makes a point to sit down when he enters the exam room. Naturally, much of his job also entails working with family members, too.
“You have to be at ease for people to be at ease with you. And you have to radiate that they have your time and attention,” he says. “And then I talk to the child right away, on their level. The most important aspect of these encounters is reassurance. It can be a minor thing, but you can’t reassure people enough.”
Dr. Krishnamurti says he was drawn to hematology because it combines pathology, procedures, and the cognitive aspects of medicine. “I am fascinated by red cell disorders and genetic disorders,” he says. “And I love working with underserved populations, which is how I got interested in sickle cell disease. I became acutely aware of the burden of this disease and the stigma of all genetic diseases, as well as the hopelessness and despair people can feel around them.
His research focuses on curative therapies, including gene therapy and how people make medical decisions, including what motivates them to take (or not take) medications, particularly with transplant patients.
Titles
- Professor of Pediatrics (Hematology/Oncology)
- Chief, Pediatric Hematology and Oncology
Education & Training
- MDUniversity of Poona, Armed Forces Medical College (1980)
Additional Information
- AB of Pediatrics, Pediatric Hematology-Oncology (2000)
- AB of Pediatrics, Pediatrics (1998)
- Chetlapalli K, Ito S, Ng DQ, Sra MS, Wang D, Krumholz H, Krishnamurti L, Pandya A, Goshua G. Haploidentical transplant, gene therapy, and standard care in sickle cell disease: a cost-effectiveness analysis. Blood Journal 2026, blood.2025032290. DOI: 10.1182/blood.2025032290.
- Jagtiani A, Hawk A, Sinha C, Gillespie S, Mirbeyk M, Burke R, Ifendu N, Reese S, Howard V, Boguslawski S, Thompson O, Ikkurthy N, El Rassi F, Smith W, Krishnamurti L, Sil S, Bakshi N. A prospective study of high-impact chronic pain in sickle cell disease: the Sickle Pain-Related Impact (SPiRIt) study. Pain 2026 PMID: 42017907, DOI: 10.1097/j.pain.0000000000003956.
- Sharma A, Abraham A, Bhatia M, Cancio M, Chaudhury S, Corbacioglu S, Guilcher G, Gupta A, Hanna R, Heeney M, John T, Krishnamurti L, LaBelle J, Rangarajan H, Shenoy S, Stenger E, Strunk C, Fitzhugh C. G‐CSF for Mobilizing CD34+ Cells in Individuals With SCD: A Word of Caution. American Journal Of Hematology 2026 PMID: 41705621, DOI: 10.1002/ajh.70235.
- Krishnamurti L, Olafimihan A, Hsu L. Informed shared decision-making or rigid eligibility and exclusion criteria for gene therapy for sickle cell disease? Blood Advances 2026, 10: 608-617. PMID: 41092461, PMCID: PMC12865566, DOI: 10.1182/bloodadvances.2025017015.
- Inam Z, Stenger E, John T, Liu K, Gillespie S, Shah R, Chellapandian D, Bhatia M, Chaudhury S, Eckrich M, Guilcher G, Hendrickson J, Hulbert M, Jaroscak J, Kasow K, Camacho‐Bydume C, Ngwube A, Olson T, Rangarajan H, Horan J, Krishnamurti L, Shenoy S, Abraham A, Nickel R. RBC Alloimmunization Impacts Pediatric Sickle Cell Disease Transplant Outcomes and Transfusion Burden: A STAR Registry Report. American Journal Of Hematology 2026, 101: 756-767. PMID: 41524608, DOI: 10.1002/ajh.70200.
- Jamwal S, Calhoun C, Mohanty S, Montgomery R, Krishnamurti L, Shaw A, Yildirim I. Unravelling the Immunological Enigma of Sickle Cell Disease: Current Understanding and Future Directions. Immunology 2025, 177: 445-456. PMID: 41387179, PMCID: PMC12826409, DOI: 10.1111/imm.70080.
- John T, Krishnamurti L. The Pediatric Clinician’s Approach to Referring Children and Adolescents with Sickle Cell Disease for Potentially Curative Therapies. Pediatric Clinics Of North America 2025, 73: 203-218. PMID: 41207739, DOI: 10.1016/j.pcl.2025.08.018.
- Chandrasekar R, Kane M, Krishnamurti L. Machine-Learning Predictive Tool for the Individualized Prediction of Outcomes of Hematopoietic Cell Transplantation for Sickle Cell Disease: Registry-Based Study. JMIR AI 2025, 4: e64519. PMID: 40952774, PMCID: PMC12435087, DOI: 10.2196/64519.
- Shenoy S, Kanter J, Kassim A, Fitzhugh C, Stenger E, Bhatia M, Pecker L, Krishnamurti L, King A. A road map for uniform, comprehensive long-term follow-up after curative therapy for sickle cell disease. Blood Advances 2025, 9: 3090-3103. PMID: 39993235, PMCID: PMC12432986, DOI: 10.1182/bloodadvances.2024013953.
- Shah N, Ngwube A, Suresh T, Sowa A, Abraham A, Anderson E, Andreansky M, Bhatia M, Chaudhury S, Cuvelier G, Dalal J, Grimley M, Jacobsohn D, Kamani N, Krajewski J, Krishnamurti L, Saini S, Skiles J, Shenoy S. Impact of Abatacept Inclusive Graft-Versus-Host Disease Prophylaxis in Pediatric Stem Cell Transplantation for Hemoglobinopathy. Transplantation And Cellular Therapy 2025, 31: 826.e1-826.e10. PMID: 40543708, DOI: 10.1016/j.jtct.2025.06.015.
- Prior D, Liang J, Deng Y, Shah N, Flagg A, Krishnamurti L. Comparison of Regimens Used for Allogeneic Matched Related Donor Hematopoietic Cell Transplantation for Sickle Cell Disease. Transplantation And Cellular Therapy 2025, 31: 594.e1-594.e13. PMID: 40379050, DOI: 10.1016/j.jtct.2025.05.004.
- Walters M, Eapen M, Liu Y, El Rassi F, Waller E, Levine J, Strouse J, Antin J, Parikh S, Bakshi N, Dampier C, Jaroscak J, Bergmann S, Wong T, Kota V, Pace B, Lekakis L, Lulla P, Nickel R, Kasow K, Popat U, Smith W, Yu L, DiFronzo N, Geller N, Kamani N, Klings E, Hassell K, Mendizabal A, Sullivan K, Neuberg D, Krishnamurti L. Hematopoietic cell transplant compared with standard care in adolescents and young adults with sickle cell disease. Blood Advances 2025, 9: 955-965. PMID: 39471440, PMCID: PMC11907447, DOI: 10.1182/bloodadvances.2024013926.
- Huang S, Gillespie S, Chou E, Liu K, Jagtiani A, Krishnamurti L, Bakshi N. Clinical phenotype of high-impact chronic pain in sickle cell disease at consultation for hematopoietic cell transplant. Journal Of Sickle Cell Disease 2025, 2: yoaf028. PMID: 41024866, PMCID: PMC12476911, DOI: 10.1093/jscdis/yoaf028.
- Gupta K, Krishnamurti L, Jain D. Sickle cell disease in India: the journey and hope for the future. Hematology 2024, 2024: 1-9. PMID: 39644008, PMCID: PMC11665512, DOI: 10.1182/hematology.2024000678.
- Gupta V, Krishnamurti L. Haematopoietic stem-cell transplantation for sickle cell disease in low-income and middle-income countries: the experience in India. The Lancet Haematology 2024, 11: e812-e813. PMID: 39482019, DOI: 10.1016/s2352-3026(24)00272-2.
- Lessard S, Rimmelé P, Ling H, Moran K, Vieira B, Lin Y, Rajani G, Hong V, Reik A, Boismenu R, Hsu B, Chen M, Cockroft B, Uchida N, Tisdale J, Alavi A, Krishnamurti L, Abedi M, Galeon I, Reiner D, Wang L, Ramezi A, Rendo P, Walters M, Levasseur D, Peters R, Harris T, Hicks A. Zinc finger nuclease-mediated gene editing in hematopoietic stem cells results in reactivation of fetal hemoglobin in sickle cell disease. Scientific Reports 2024, 14: 24298. PMID: 39414860, PMCID: PMC11484757, DOI: 10.1038/s41598-024-74716-7.
- Arnold S, Bakshi N, Ross D, Smith C, Sinha C, Veludhandi A, Dutreuil V, Bai S, Meacham L, Guilcher G, Bhatia M, Abraham A, Kasow K, Haight A, Rassi F, Stenger E, Lipscomb J, Krishnamurti L. Long‐term quality of life after hematopoietic cell transplant for sickle cell disease in childhood: A STELLAR interim analysis. American Journal Of Hematology 2024, 99: 2037-2040. PMID: 39105410, DOI: 10.1002/ajh.27436.
- George S, Veludhandi A, Xiang Y, Liu K, Stenger E, Arnold S, Mehta A, Schirmer D, Spencer J, Guilcher G, Bhatia M, Abraham A, Gomez-Lobo V, Krishnamurti L, Meacham L. Reproductive Health Assessment and Reports of Fertility Counseling in Pediatric and Adolescent Patients with Sickle Cell Disease After Hematopoietic Cell Transplantation. Transplantation And Cellular Therapy 2024, 30: 912.e1-912.e13. PMID: 38972510, PMCID: PMC11344653, DOI: 10.1016/j.jtct.2024.06.029.
- Jagtiani A, Chou E, Gillespie S, Liu K, Krishnamurti L, McClish D, Smith W, Bakshi N. High-impact chronic pain in sickle cell disease: insights from the Pain in Sickle Cell Epidemiology Study (PiSCES). Pain 2024, 165: 2364-2369. PMID: 38787626, PMCID: PMC11404329, DOI: 10.1097/j.pain.0000000000003262.
- Jain D, Gupta M, Madkaikar M, Jena R, Khargekar N, Saraf S, Krishnamurti L, Gupta K. Sickle cell disease in India: current status and progress. The Lancet Haematology 2024, 11: e322-e323. PMID: 38701819, DOI: 10.1016/s2352-3026(24)00109-1.
- Krishnamurti L, Liang J, He Z, Deng Y, Nallagatla V, Hamidi R, Flagg A, Shah N. Incidence and risk factors of pain crisis after hematopoietic cell transplantation for sickle cell disease. Blood Advances 2024, 8: 1908-1919. PMID: 38324722, PMCID: PMC11021890, DOI: 10.1182/bloodadvances.2023010749.
- Eapen M, Kou J, Andreansky M, Bhatia M, Brochstein J, Chaudhury S, Haight A, Haines H, Jacobsohn D, Jaroscak J, Kasow K, Krishnamurti L, Levine J, Leung K, Margolis D, Yu L, Horowitz M, Kamani N, Walters M, Shenoy S. Long‐term outcomes after unrelated donor transplantation for severe sickle cell disease on the BMT CTN 0601 trial. American Journal Of Hematology 2024, 99: 785-788. PMID: 38343182, PMCID: PMC10947844, DOI: 10.1002/ajh.27251.
- Ito S, Pandya A, Hauser R, Krishnamurti L, Stites E, Tormey C, Krumholz H, Hendrickson J, Goshua G. Decreasing alloimmunization‐specific mortality in sickle cell disease in the United States: Cost‐effectiveness of a shared transfusion resource. American Journal Of Hematology 2024, 99: 570-576. PMID: 38279581, DOI: 10.1002/ajh.27211.
- Goshua G, Calhoun C, Ito S, James L, Luviano A, Krishnamurti L, Pandya A. Distributional Cost-Effectiveness of Equity-Enhancing Gene Therapy in Sickle Cell Disease in the United States. Annals Of Internal Medicine 2023, 176: 779-787. PMID: 37247420, PMCID: PMC10370480, DOI: 10.7326/m22-3272.
- Meacham L, George S, Veludhandi A, Pruett M, Haight A, Arnold S, Elchuri S, Stenger E, Krishnamurti L. Female Reproductive Health Outcomes after Hematopoietic Cell Transplantation for Sickle Cell Disease: Is Reduced Intensity Better Than Myeloablative Conditioning? Transplantation And Cellular Therapy 2023, 29: 531.e1-531.e4. PMID: 37169288, DOI: 10.1016/j.jtct.2023.05.004.
- Sinha C, Meacham L, Bakshi N, Ross D, Krishnamurti L. Parental perspective on the risk of infertility and fertility preservation options for children and adolescents with sickle cell disease considering hematopoietic stem cell transplantation. Pediatric Blood & Cancer 2023, 70: e30276-e30276. PMID: 37051746, PMCID: PMC10544372, DOI: 10.1002/pbc.30276.
- Chiang K, Gupta A, Sundd P, Krishnamurti L. Thrombo-Inflammation in COVID-19 and Sickle Cell Disease: Two Faces of the Same Coin. Biomedicines 2023, 11: 338. PMID: 36830874, PMCID: PMC9953430, DOI: 10.3390/biomedicines11020338.
- Eapen M, Brazauskas R, Williams D, Walters M, St Martin A, Jacobs B, Antin J, Bona K, Chaudhury S, Coleman-Cowger V, DiFronzo N, Esrick E, Field J, Fitzhugh C, Kanter J, Kapoor N, Kohn D, Krishnamurti L, London W, Pulsipher M, Talib S, Thompson A, Waller E, Wun T, Horowitz M. Secondary Neoplasms After Hematopoietic Cell Transplant for Sickle Cell Disease. Journal Of Clinical Oncology 2023, 41: 2227-2237. PMID: 36623245, PMCID: PMC10448940, DOI: 10.1200/jco.22.01203.
- Bakshi N, Astles R, Chou E, Hurreh A, Sil S, Sinha C, Sanders K, Peddineni M, Gillespie S, Keesari R, Krishnamurti L. Multimodal phenotyping and correlates of pain following hematopoietic cell transplant in children with sickle cell disease. Pediatric Blood & Cancer 2022, 70: e30046-e30046. PMID: 36322607, PMCID: PMC9820671, DOI: 10.1002/pbc.30046.
- Stenger E, Xiang Y, Wetzel M, Gillespie S, Chellapandian D, Shah R, Arnold S, Bhatia M, Chaudhury S, Eckrich M, Kanter J, Kasow K, Krajewski J, Nickel R, Ngwube A, Olson T, Rangarajan H, Wobma H, Guilcher G, Horan J, Krishnamurti L, Shenoy S, Abraham A. Long-Term Organ Function After HCT for SCD: A Report From the Sickle Cell Transplant Advocacy and Research Alliance. Transplantation And Cellular Therapy 2022, 29: 47.e1-47.e10. PMID: 36273784, DOI: 10.1016/j.jtct.2022.10.012.
- Krishnamurti L, Neuberg D, Sullivan K, Smith S, Eapen M, Walters M. Enrollment Lessons from a Biological Assignment Study of Marrow Transplantation versus Standard Care for Adolescents and Young Adults with Sickle Cell Disease: Considerations for Future Gene and Cellular Therapy Trials. Transplantation And Cellular Therapy 2022, 29: 217-221. PMID: 36270432, PMCID: PMC10539686, DOI: 10.1016/j.jtct.2022.10.008.
- Quarmyne M, Ross D, Sinha C, Bakshi N, Boudreaux J, Krishnamurti L. Decision-making about gene therapy in transfusion dependent thalassemia. BMC Pediatrics 2022, 22: 536. PMID: 36085025, PMCID: PMC9461218, DOI: 10.1186/s12887-022-03598-3.
- Krishnamurti L, Arnold S, Haight A, Abraham A, Guilcher G, John T, Bakshi N, Shenoy S, Syrjala K, Martin P, Chaudhury S, Eames G, Olowoselu O, Hsieh M, De La Fuente J, Kasow K, Stenger E, Mertens A, El-Rassi F, Lane P, Shaw B, Meacham L, Archer D. Sickle Cell Transplantation Evaluation of Long-term and Late Effects Registry (STELLAR) to Compare Long-term Outcomes After Hematopoietic Cell Transplantation to Those in Siblings Without Sickle Cell Disease and in Nontransplanted Individuals With Sickle Cell Disease: Design and Feasibility Study. JMIR Research Protocols 2022, 11: e36780. PMID: 35793124, PMCID: PMC9301564, DOI: 10.2196/36780.
- Rodgers-Melnick S, Lin L, Gam K, Souza de Santana Carvalho E, Jenerette C, Rowland D, Little J, Dusek J, Bakshi N, Krishnamurti L. Effects of Music Therapy on Quality of Life in Adults with Sickle Cell Disease (MUSIQOLS): A Mixed Methods Feasibility Study [Erratum]. Journal Of Pain Research 2022, 15: 1123-1124. PMID: 35469252, PMCID: PMC9034844, DOI: 10.2147/jpr.s370799.
- Day J, Takemoto C, Sharathkumar A, Makhani S, Gupta A, Bitner S, Josephson C, Bloch E, Tobian A, Krishnamurti L, Goel R. Associated comorbidities, healthcare utilization & mortality in hospitalized patients with haemophilia in the United States: Contemporary nationally representative estimates. Haemophilia 2022, 28: 532-541. PMID: 35412659, PMCID: PMC9540439, DOI: 10.1111/hae.14557.
- Rodgers-Melnick S, Lin L, Gam K, de Santana Carvalho E, Jenerette C, Rowland D, Little J, Dusek J, Bakshi N, Krishnamurti L. Effects of Music Therapy on Quality of Life in Adults with Sickle Cell Disease (MUSIQOLS): A Mixed Methods Feasibility Study. Journal Of Pain Research 2022, 15: 71-91. PMID: 35046718, PMCID: PMC8760983, DOI: 10.2147/jpr.s337390.
- Chiang K, Rizk J, Nelson D, Krishnamurti L, Subbian S, Imig J, Khan I, Reddy S, Gupta A. Ramatroban for chemoprophylaxis and treatment of COVID-19: David takes on Goliath. Expert Opinion On Therapeutic Targets 2022, 26: 13-28. PMID: 35068281, PMCID: PMC10119876, DOI: 10.1080/14728222.2022.2031975.
- Krishnamurti L. Hematopoietic cell transplantation for sickle cell disease: updates and future directions. Hematology 2021, 2021: 181-189. PMID: 34889368, PMCID: PMC8791142, DOI: 10.1182/hematology.2021000251.
- Veludhandi A, Ross D, Sinha C, McCracken C, Bakshi N, Krishnamurti L. A Decision Support Tool for Allogeneic Hematopoietic Stem Cell Transplantation for Children With Sickle Cell Disease: Acceptability and Usability Study. JMIR Formative Research 2021, 5: e30093. PMID: 34709190, PMCID: PMC8587189, DOI: 10.2196/30093.
- Katoch D, Krishnamurti L. Assessing Patient Preferences for Treatment Options for Pediatric Sickle Cell Disease: A Critical Review of Quantitative and Qualitative Studies. Patient Preference And Adherence 2021, 15: 2221-2229. PMID: 34629865, PMCID: PMC8493010, DOI: 10.2147/ppa.s264918.
- Bakshi N, Gillespie S, McClish D, McCracken C, Smith W, Krishnamurti L. Intraindividual pain variability and phenotypes of pain in sickle cell disease: a secondary analysis from the Pain in Sickle Cell Epidemiology Study. Pain 2021, 163: 1102-1113. PMID: 34538841, PMCID: PMC9100443, DOI: 10.1097/j.pain.0000000000002479.
- Mupfudze T, Meyer C, Preussler J, Mau L, Bolon Y, Steinert P, Arnold S, Saber W, Krishnamurti L. Hematopoietic Cell Transplantation Outcomes among Medicaid and Privately Insured Patients with Sickle Cell Disease. Transplantation And Cellular Therapy 2021, 27: 685.e1-685.e8. PMID: 33895405, PMCID: PMC8680220, DOI: 10.1016/j.jtct.2021.04.009.
- Bakshi N, Cooley A, Ross D, Hawkins L, Sullivan M, Astles R, Sinha C, Katoch D, Peddineni M, Gee B, Lane P, Krishnamurti L. A pilot study of the acceptability, feasibility and safety of yoga for chronic pain in sickle cell disease. Complementary Therapies In Medicine 2021, 59: 102722. PMID: 33892094, PMCID: PMC8284565, DOI: 10.1016/j.ctim.2021.102722.
- Krishnamurti L. Gaps in Medicaid Coverage and Financial Toxicity: A Health Disparity in Hematopoietic Cell Transplantation for Sickle Cell Disease. Transplantation And Cellular Therapy 2021, 27: 284-285. PMID: 33836866, DOI: 10.1016/j.jtct.2021.03.016.
- Krishnamurti L. Hematopoietic Cell Transplantation for Sickle Cell Disease. Frontiers In Pediatrics 2021, 8: 551170. PMID: 33469520, PMCID: PMC7813811, DOI: 10.3389/fped.2020.551170.
- Sheshadri V, Shabeer P, Santhirapala V, Jayaram A, Krishnamurti L, Menon N. Mortality in sickle cell disease: A population‐based study in an aboriginal community in the Gudalur Valley, Nilgiris, Tamil Nadu, India. Pediatric Blood & Cancer 2020, 68: e28875. PMID: 33381914, DOI: 10.1002/pbc.28875.
- Ross D, Sinha C, Bakshi N, Krishnamurti L. Educational needs of patients and caregivers living with sickle cell disease results in development of web‐based patient decision aid. Journal Of Advanced Nursing 2020, 77: 1432-1441. PMID: 33277763, DOI: 10.1111/jan.14704.
- Sinha C, Bakshi N, Ross D, Loewenstein G, Krishnamurti L. Primary caregiver decision‐making in hematopoietic cell transplantation and gene therapy for sickle cell disease. Pediatric Blood & Cancer 2020, 68: e28749-e28749. PMID: 33034129, PMCID: PMC8246626, DOI: 10.1002/pbc.28749.
- Tisdale J, Pierciey F, Bonner M, Thompson A, Krishnamurti L, Mapara M, Kwiatkowski J, Shestopalov I, Ribeil J, Huang W, Asmal M, Kanter J, Walters M. Safety and feasibility of hematopoietic progenitor stem cell collection by mobilization with plerixafor followed by apheresis vs bone marrow harvest in patients with sickle cell disease in the multi‐center HGB‐206 trial. American Journal Of Hematology 2020, 95: e239-e242. PMID: 32401372, DOI: 10.1002/ajh.25867.
- Bakshi N, Katoch D, Sinha C, Ross D, Quarmyne M, Loewenstein G, Krishnamurti L. Assessment of Patient and Caregiver Attitudes and Approaches to Decision-Making Regarding Bone Marrow Transplant for Sickle Cell Disease. JAMA Network Open 2020, 3: e206742. PMID: 32469414, PMCID: PMC7260617, DOI: 10.1001/jamanetworkopen.2020.6742.
- Hawkins L, Sinha C, Ross D, Yee M, Quarmyne M, Krishnamurti L, Bakshi N. Patient and family experience with chronic transfusion therapy for sickle cell disease: A qualitative study. BMC Pediatrics 2020, 20: 172. PMID: 32305060, PMCID: PMC7165370, DOI: 10.1186/s12887-020-02078-w.
- Krishnamurti L. Should young children with sickle cell disease and an available human leukocyte antigen identical sibling donor be offered hematopoietic cell transplantation? Hematology/Oncology And Stem Cell Therapy 2020, 13: 53-57. PMID: 32202246, DOI: 10.1016/j.hemonc.2019.12.008.
- Matthie N, Jenerette C, Gibson A, Paul S, Higgins M, Krishnamurti L. Prevalence and predictors of chronic pain intensity and disability among adults with sickle cell disease. Health Psychology Open 2020, 7: 2055102920917250. PMID: 32426150, PMCID: PMC7218472, DOI: 10.1177/2055102920917250.
- Stenger E, Shenoy S, Krishnamurti L. How I treat sickle cell disease with hematopoietic cell transplantation. Blood 2019, 134: 2249-2260. PMID: 31697818, PMCID: PMC6923666, DOI: 10.1182/blood.2019000821.
- Farrell A, Panepinto J, Desai A, Kassim A, Lebensburger J, Walters M, Bauer D, Blaylark R, DiMichele D, Gladwin M, Green N, Hassell K, Kato G, Klings E, Kohn D, Krishnamurti L, Little J, Makani J, Malik P, McGann P, Minniti C, Morris C, Odame I, Oneal P, Setse R, Sharma P, Shenoy S. End points for sickle cell disease clinical trials: renal and cardiopulmonary, cure, and low-resource settings. Blood Advances 2019, 3: 4002-4020. PMID: 31809537, PMCID: PMC6963248, DOI: 10.1182/bloodadvances.2019000883.
- Krishnamurti L, Ross D, Sinha C, Leong T, Bakshi N, Mittal N, Veludhandi D, Pham A, Taneja A, Gupta K, Nwanze J, Matthews A, Joshi S, Olivieri V, Arjunan S, Okonkwo I, Lukombo I, Lane P, Bakshi N, Loewenstein G. Comparative Effectiveness of a Web-Based Patient Decision Aid for Therapeutic Options for Sickle Cell Disease: Randomized Controlled Trial. Journal Of Medical Internet Research 2019, 21: e14462. PMID: 31799940, PMCID: PMC6934048, DOI: 10.2196/14462.
- Khemani K, Katoch D, Krishnamurti L. Curative Therapies for Sickle Cell Disease. Ochsner Journal 2019, 19: 131-137. PMID: 31258425, PMCID: PMC6584191, DOI: 10.31486/toj.18.0044.
- Sinha C, Bakshi N, Ross D, Krishnamurti L. Management of Chronic Pain in Adults Living With Sickle Cell Disease in the Era of the Opioid Epidemic. JAMA Network Open 2019, 2: e194410. PMID: 31125105, PMCID: PMC6632133, DOI: 10.1001/jamanetworkopen.2019.4410.
- Krishnamurti L, Neuberg D, Sullivan K, Kamani N, Abraham A, Campigotto F, Zhang W, Dahdoul T, De Castro L, Parikh S, Bakshi N, Haight A, Hassell K, Loving R, Rosenthal J, Smith S, Smith W, Spearman M, Stevenson K, Wu C, Wiedl C, Waller E, Walters M. Bone marrow transplantation for adolescents and young adults with sickle cell disease: Results of a prospective multicenter pilot study. American Journal Of Hematology 2019, 94: 446-454. PMID: 30637784, PMCID: PMC6542639, DOI: 10.1002/ajh.25401.
- Goel R, Chopra S, Tobian A, Ness P, Frank S, Cushing M, Vasovic L, Kaicker S, Takemoto C, Josephson C, Nellis M, Bussel J, Krishnamurti L. Platelet transfusion practices in immune thrombocytopenia related hospitalizations. Transfusion 2018, 59: 169-176. PMID: 30520045, DOI: 10.1111/trf.15069.
- Matthie N, Ross D, Sinha C, Khemani K, Bakshi N, Krishnamurti L. A Qualitative Study of Chronic Pain and Self-Management in Adults with Sickle Cell Disease. Journal Of The National Medical Association 2018, 111: 158-168. PMID: 30266214, PMCID: PMC6433553, DOI: 10.1016/j.jnma.2018.08.001.
- Phillips L, Krishnamurti L, Rytting H, Olson T. Ovarian Sertoli–Leydig tumor after bone marrow transplant for sickle cell disease. Pediatric Blood & Cancer 2018, 65: e27367. PMID: 30039911, DOI: 10.1002/pbc.27367.
- Sinha C, Bakshi N, Ross D, Krishnamurti L. From trust to skepticism: An in-depth analysis across age groups of adults with sickle cell disease on their perspectives regarding hydroxyurea. PLOS ONE 2018, 13: e0199375. PMID: 29949647, PMCID: PMC6021071, DOI: 10.1371/journal.pone.0199375.
- Bakshi N, Lukombo I, Belfer I, Krishnamurti L. Pain catastrophizing is associated with poorer health-related quality of life in pediatric patients with sickle cell disease. Journal Of Pain Research 2018, 11: 947-953. PMID: 29773954, PMCID: PMC5947835, DOI: 10.2147/jpr.s151198.
- Kato G, Piel F, Reid C, Gaston M, Ohene-Frempong K, Krishnamurti L, Smith W, Panepinto J, Weatherall D, Costa F, Vichinsky E. Sickle cell disease. Nature Reviews Disease Primers 2018, 4: 18010. PMID: 29542687, DOI: 10.1038/nrdp.2018.10.
- Zhang Y, Belfer I, Nouraie M, Zeng Q, Goel R, Chu Y, Krasiy I, Krishnamurti L. Association of genetic variation in COMT gene with pain related to sickle cell disease in patients from the walk-PHaSST study. Journal Of Pain Research 2018, 11: 537-543. PMID: 29559808, PMCID: PMC5856032, DOI: 10.2147/jpr.s149958.
- Bakshi N, Ross D, Krishnamurti L. Presence of pain on three or more days of the week is associated with worse patient reported outcomes in adults with sickle cell disease. Journal Of Pain Research 2018, 11: 313-318. PMID: 29445298, PMCID: PMC5810514, DOI: 10.2147/jpr.s150065.
- Bakshi N, Lukombo I, Belfer I, Krishnamurti L. Quantitative sensory testing is feasible and is well-tolerated in patients with sickle cell disease following a vaso-occlusive episode. Journal Of Pain Research 2018, 11: 435-443. PMID: 29503580, PMCID: PMC5827673, DOI: 10.2147/jpr.s150066.
- Jain S, Bakshi N, Krishnamurti L. Acute Chest Syndrome in Children with Sickle Cell Disease. Pediatric Allergy Immunology And Pulmonology 2017, 30: 191-201. PMID: 29279787, PMCID: PMC5733742, DOI: 10.1089/ped.2017.0814.
- Bakshi N, Sinha C, Ross D, Khemani K, Loewenstein G, Krishnamurti L. Proponent or collaborative: Physician perspectives and approaches to disease modifying therapies in sickle cell disease. PLOS ONE 2017, 12: e0178413. PMID: 28727801, PMCID: PMC5518995, DOI: 10.1371/journal.pone.0178413.
- Panepinto J, Paul Scott J, Badaki-Makun O, Darbari D, Chumpitazi C, Airewele G, Ellison A, Smith-Whitley K, Mahajan P, Sarnaik S, Charles Casper T, Cook L, Leonard J, Hulbert M, Powell E, Liem R, Hickey R, Krishnamurti L, Hillery C, Brousseau D, for the Pediatric Emergency Care Applied Research Network (PECARN). Determining the longitudinal validity and meaningful differences in HRQL of the PedsQL™ Sickle Cell Disease Module. Health And Quality Of Life Outcomes 2017, 15: 124. PMID: 28606098, PMCID: PMC5468970, DOI: 10.1186/s12955-017-0700-2.
- Bakshi N, Lukombo I, Shnol H, Belfer I, Krishnamurti L. Psychological Characteristics and Pain Frequency Are Associated With Experimental Pain Sensitivity in Pediatric Patients With Sickle Cell Disease. Journal Of Pain 2017, 18: 1216-1228. PMID: 28602692, DOI: 10.1016/j.jpain.2017.05.005.
- Bakshi N, Smith M, Ross D, Krishnamurti L. Novel Metrics in the Longitudinal Evaluation of Pain Data in Sickle Cell Disease. The Clinical Journal Of Pain 2017, 33: 517-527. PMID: 27584817, DOI: 10.1097/ajp.0000000000000431.
- Stenger E, Chinnadurai R, Yuan S, Garcia M, Arafat D, Gibson G, Krishnamurti L, Galipeau J. Bone Marrow–Derived Mesenchymal Stromal Cells from Patients with Sickle Cell Disease Display Intact Functionality. Transplantation And Cellular Therapy 2017, 23: 736-745. PMID: 28132869, PMCID: PMC5390328, DOI: 10.1016/j.bbmt.2017.01.081.
- Gluckman E, Cappelli B, Bernaudin F, Labopin M, Volt F, Carreras J, Pinto Simões B, Ferster A, Dupont S, de la Fuente J, Dalle J, Zecca M, Walters M, Krishnamurti L, Bhatia M, Leung K, Yanik G, Kurtzberg J, Dhedin N, Kuentz M, Michel G, Apperley J, Lutz P, Neven B, Bertrand Y, Vannier J, Ayas M, Cavazzana M, Matthes-Martin S, Rocha V, Elayoubi H, Kenzey C, Bader P, Locatelli F, Ruggeri A, Eapen M. Sickle cell disease: an international survey of results of HLA-identical sibling hematopoietic stem cell transplantation. Blood 2016, 129: 1548-1556. PMID: 27965196, PMCID: PMC5356458, DOI: 10.1182/blood-2016-10-745711.
- Shenoy S, Eapen M, Panepinto J, Logan B, Wu J, Abraham A, Brochstein J, Chaudhury S, Godder K, Haight A, Kasow K, Leung K, Andreansky M, Bhatia M, Dalal J, Haines H, Jaroscak J, Lazarus H, Levine J, Krishnamurti L, Margolis D, Megason G, Yu L, Pulsipher M, Gersten I, DiFronzo N, Horowitz M, Walters M, Kamani N. A trial of unrelated donor marrow transplantation for children with severe sickle cell disease. Blood 2016, 128: 2561-2567. PMID: 27625358, PMCID: PMC5123194, DOI: 10.1182/blood-2016-05-715870.
- Krishnamurti L. Iron-Deficiency Anemia. 2016, 2217-2227. DOI: 10.1542/9781610020473-part07-ch279.
- Jain D, Arjunan A, Sarathi V, Jain H, Bhandarwar A, Vuga M, Krishnamurti L. Clinical events in a large prospective cohort of children with sickle cell disease in Nagpur, India: evidence against a milder clinical phenotype in India. Pediatric Blood & Cancer 2016, 63: 1814-1821. PMID: 27279568, DOI: 10.1002/pbc.26085.
- Arnold S, Bhatia M, Horan J, Krishnamurti L. Haematopoietic stem cell transplantation for sickle cell disease – current practice and new approaches. British Journal Of Haematology 2016, 174: 515-525. PMID: 27255787, DOI: 10.1111/bjh.14167.
- Sayan M, Cassidy R, Butker E, Nanda R, Krishnamurti L, Khan M, Esiashvili N. Gonadal shielding technique to preserve fertility in male pediatric patients treated with total body irradiation for stem cell transplantation. Bone Marrow Transplantation 2016, 51: 997-998. PMID: 26950374, DOI: 10.1038/bmt.2016.25.
- Stenger E, Krishnamurti L, Galipeau J. Mesenchymal stromal cells to modulate immune reconstitution early post-hematopoietic cell transplantation. BMC Immunology 2015, 16: 74. PMID: 26674007, PMCID: PMC4681052, DOI: 10.1186/s12865-015-0135-7.
- Walters M, De Castro L, Sullivan K, Krishnamurti L, Kamani N, Bredeson C, Neuberg D, Hassell K, Farnia S, Campbell A, Petersdorf E. Indications and Results of HLA-Identical Sibling Hematopoietic Cell Transplantation for Sickle Cell Disease. Transplantation And Cellular Therapy 2015, 22: 207-211. PMID: 26500093, PMCID: PMC5031360, DOI: 10.1016/j.bbmt.2015.10.017.
- Creary S, Zickmund S, Ross D, Krishnamurti L, Bogen D. Hydroxyurea therapy for children with sickle cell disease: describing how caregivers make this decision. BMC Research Notes 2015, 8: 372. PMID: 26303306, PMCID: PMC4548690, DOI: 10.1186/s13104-015-1344-0.
- Brousseau D, Scott J, Badaki-Makun O, Darbari D, Chumpitazi C, Airewele G, Ellison A, Smith-Whitley K, Mahajan P, Sarnaik S, Casper T, Cook L, Dean J, Leonard J, Hulbert M, Powell E, Liem R, Hickey R, Krishnamurti L, Hillery C, Nimmer M, Panepinto J, Network F. A multicenter randomized controlled trial of intravenous magnesium for sickle cell pain crisis in children. Blood 2015, 126: 1651-1657. PMID: 26232172, PMCID: PMC4591790, DOI: 10.1182/blood-2015-05-647107.
- Ferrari R, Parker L, Grubs R, Krishnamurti L. Sickle Cell Trait Screening of Collegiate Athletes: Ethical Reasons for Program Reform. Journal Of Genetic Counseling 2015, 24: 873-877. PMID: 26040250, DOI: 10.1007/s10897-015-9849-1.
- Bakshi N, Stinson J, Ross D, Lukombo I, Mittal N, Joshi S, Belfer I, Krishnamurti L. Development, Content Validity, and User Review of a Web-based Multidimensional Pain Diary for Adolescent and Young Adults With Sickle Cell Disease. The Clinical Journal Of Pain 2015, 31: 580-590. PMID: 25565585, DOI: 10.1097/ajp.0000000000000195.
- Telen M, Wun T, McCavit T, De Castro L, Krishnamurti L, Lanzkron S, Hsu L, Smith W, Rhee S, Magnani J, Thackray H. Randomized phase 2 study of GMI-1070 in SCD: reduction in time to resolution of vaso-occlusive events and decreased opioid use. Blood 2015, 125: 2656-2664. PMID: 25733584, PMCID: PMC4408290, DOI: 10.1182/blood-2014-06-583351.
- Goel R, Ness P, Takemoto C, Krishnamurti L, King K, Tobian A. Platelet transfusions in platelet consumptive disorders are associated with arterial thrombosis and in-hospital mortality. Blood 2015, 125: 1470-1476. PMID: 25588677, PMCID: PMC4342358, DOI: 10.1182/blood-2014-10-605493.
- Italia Y, Krishnamurti L, Mehta V, Raicha B, Italia K, Mehta P, Ghosh K, Colah R. Feasibility of a Newborn Screening and Follow-up Programme for Sickle Cell Disease among South Gujarat (India) Tribal Populations. Journal Of Medical Screening 2014, 22: 1-7. PMID: 25341880, DOI: 10.1177/0969141314557372.
- Kato-Lin Y, Krishnamurti L, Padman R, Seltman H. Does e-pain plan improve management of sickle cell disease associated vaso-occlusive pain crisis? A mixed methods evaluation. International Journal Of Medical Informatics 2014, 83: 814-824. PMID: 25179666, DOI: 10.1016/j.ijmedinf.2014.08.003.
- Creary S, Krishnamurti L. Prodromal Illness Before Acute Chest Syndrome in Pediatric Patients With Sickle Cell Disease. Journal Of Pediatric Hematology/Oncology 2014, 36: 480-483. PMID: 24633302, DOI: 10.1097/mph.0000000000000146.
- Turaka K, Kietz D, Krishnamurti L, Mitchell E, Scanga H, Fu V, Sylvester C. Carcinoma-associated retinopathy in a young teenager with immature teratoma of the ovary. Journal Of American Association For Pediatric Ophthalmology And Strabismus 2014, 18: 396-398. PMID: 25173906, DOI: 10.1016/j.jaapos.2014.03.007.
- Shrikhande A, Arjunan A, Agarwal A, Dani A, Tijare J, Gettig E, Krishnamurti L. Prevalence of the βS Gene Among Scheduled Castes, Scheduled Tribes and Other Backward Class Groups in Central India. Hemoglobin 2014, 38: 230-235. PMID: 25023085, DOI: 10.3109/03630269.2014.931287.
- Gladwin M, Barst R, Gibbs J, Hildesheim M, Sachdev V, Nouraie M, Hassell K, Little J, Schraufnagel D, Krishnamurti L, Novelli E, Girgis R, Morris C, Rosenzweig E, Badesch D, Lanzkron S, Castro O, Taylor J, Goldsmith J, Kato G, Gordeuk V, Machado R, Investigators and Patients O. Risk Factors for Death in 632 Patients with Sickle Cell Disease in the United States and United Kingdom. PLOS ONE 2014, 9: e99489. PMID: 24988120, PMCID: PMC4079316, DOI: 10.1371/journal.pone.0099489.
- Klings E, Machado R, Morris C, Gordeuk V, Kato G, Ataga K, Castro O, Hsu L, Telen M, Krishnamurti L, Steinberg M, Gladwin M. Reply: Practice Guideline for Pulmonary Hypertension in Sickle Cell: Direct Evidence Needed before Universal Adoption. American Journal Of Respiratory And Critical Care Medicine 2014, 190: 238-240. PMID: 25025360, PMCID: PMC4226058, DOI: 10.1164/rccm.201404-0733le.
- Krishnamurti L, Smith‐Packard B, Gupta A, Campbell M, Gunawardena S, Saladino R. Impact of individualized pain plan on the emergency management of children with sickle cell disease. Pediatric Blood & Cancer 2014, 61: 1747-1753. PMID: 24962217, DOI: 10.1002/pbc.25024.
- Helton KJ, Investigators F, Adams R, Kesler K, Lockhart A, Aygun B, Driscoll C, Heeney M, Jackson S, Krishnamurti L, Miller S, Sarnaik S, Schultz W, Ware R. Magnetic resonance imaging/angiography and transcranial Doppler velocities in sickle cell anemia: results from the SWiTCH trial. Blood 2014, 124: 891-898. PMID: 24914136, PMCID: PMC4126329, DOI: 10.1182/blood-2013-12-545186.
- Bai Y, Krishnamurti L, Jia W, Mao Z, Sun M. An Electronic Six-Minute Walk Test Platform for Clinical Applications. 2014, 1-2. DOI: 10.1109/nebec.2014.6972715.
- Klings E, Machado R, Barst R, Morris C, Mubarak K, Gordeuk V, Kato G, Ataga K, Gibbs J, Castro O, Rosenzweig E, Sood N, Hsu L, Wilson K, Telen M, Decastro L, Krishnamurti L, Steinberg M, Badesch D, Gladwin M. An Official American Thoracic Society Clinical Practice Guideline: Diagnosis, Risk Stratification, and Management of Pulmonary Hypertension of Sickle Cell Disease. American Journal Of Respiratory And Critical Care Medicine 2014, 189: 727-740. PMID: 24628312, PMCID: PMC3983842, DOI: 10.1164/rccm.201401-0065st.
- Creary S, Gladwin M, Byrne M, Hildesheim M, Krishnamurti L. A pilot study of electronic directly observed therapy to improve hydroxyurea adherence in pediatric patients with sickle‐cell disease. Pediatric Blood & Cancer 2014, 61: 1068-1073. PMID: 24436121, DOI: 10.1002/pbc.24931.
- Nimgaonkar V, Krishnamurti L, Prabhakar H, Menon N. Comprehensive integrated care for patients with sickle cell disease in a remote aboriginal tribal population in southern India. Pediatric Blood & Cancer 2013, 61: 702-705. PMID: 24347362, DOI: 10.1002/pbc.24723.
- George M, Novelli E, Shigemura N, Simon M, Feingold B, Krishnamurti L, Morrell M, Gries C, Haider S, Johnson B, Crespo M, Bhama J, Bermudez C, Yousem S, Toyoda Y, Champion H, Pilewski J, Gladwin M. First Successful Lung Transplantation for Sickle Cell Disease with Severe Pulmonary Arterial Hypertension and Pulmonary Veno‐Occlusive Disease. Pulmonary Circulation 2013, 3: 952-958. PMID: 25006411, PMCID: PMC4070828, DOI: 10.1086/674749.
- Berg A, Courtney R, Krishnamurti L, Triulzi D, Yazer M. Is intensive monitoring during the first transfusion in pediatric patients necessary? Hematology 2013, 19: 304-308. PMID: 24074624, DOI: 10.1179/1607845413y.0000000122.
- Wun T, Soulieres D, Frelinger A, Krishnamurti L, Novelli E, Kutlar A, Ataga K, Knupp C, McMahon L, Strouse J, Zhou C, Heath L, Nwachuku C, Jakubowski J, Riesmeyer J, Winters K. A double-blind, randomized, multicenter phase 2 study of prasugrel versus placebo in adult patients with sickle cell disease. Journal Of Hematology & Oncology 2013, 6: 17. PMID: 23414938, PMCID: PMC3585853, DOI: 10.1186/1756-8722-6-17.
- Cruz R, Ranganathan S, Mazariegos G, Soltys K, Nayyar N, Sun Q, Bond G, Shaw P, Haberman K, Krishnamurti L, Marsh J, Humar A, Sindhi R. Analysis of national and single-center incidence and survival after liver transplantation for hepatoblastoma: New trends and future opportunities. Surgery 2013, 153: 150-159. PMID: 23331862, DOI: 10.1016/j.surg.2012.11.006.
- Nouraie M, Lee J, Zhang Y, Kanias T, Zhao X, Xiong Z, Oriss T, Zeng Q, Kato G, Gibbs J, Hildesheim M, Sachdev V, Barst R, Machado R, Hassell K, Little J, Schraufnagel D, Krishnamurti L, Novelli E, Girgis R, Morris C, Rosenzweig E, Badesch D, Lanzkron S, Castro O, Goldsmith J, Gordeuk V, Gladwin M. The relationship between the severity of hemolysis, clinical manifestations and risk of death in 415 patients with sickle cell anemia in the US and Europe. Haematologica 2012, 98: 464-472. PMID: 22983573, PMCID: PMC3659937, DOI: 10.3324/haematol.2012.068965.
- GOEL R, KRISHNAMURTI L. Mortality, health care utilization and associated diagnoses in hospitalized patients with haemophilia in the United States: first reported nationwide estimates. Haemophilia 2012, 18: 688-692. PMID: 22500777, DOI: 10.1111/j.1365-2516.2012.02774.x.
- Gheorghe G, Galambos C, Jain S, Krishnamurti L, Jaffe R. A Novel TCIRG1 Gene Mutation Leads to Severe Osteopetrosis with Altered Content of Monocytes/Macrophages in Several Organs. Pediatric And Developmental Pathology 2012, 15: 156-159. PMID: 22280207, DOI: 10.2350/11-05-1032-cr.1.
- Dovey S, Krishnamurti L, Sanfilippo J, Gunawardena S, Mclendon P, Campbell M, Alway S, Efymow B, Gracia C. Oocyte cryopreservation in a patient with sickle cell disease prior to hematopoietic stem cell transplantation: first report. Journal Of Assisted Reproduction And Genetics 2012, 29: 265-269. PMID: 22219083, PMCID: PMC3288130, DOI: 10.1007/s10815-011-9698-2.
- Wetzler M, Brown P, Hunger S, Sheppard C, Hillyer C, Guinan E, Rodriguez N, Jamieson K, Morales-Arias J, Pietrangelo A, Chitlur M, Kulkarni R, Carpenter S, Mazloom A, Paulman P, Kyle R, Rajkumar S, Shammo J, Bonilla M, Evens A, Cornett P, Andrès E, Sood S, Abrams C, Duggan P, Pierach C, Novelli E, Gladwin M, Krishnamurti L, Holstein S, Hohl R, Millward P, Brecher M, Kiss J. 13 Hematology. 2012, 767-871. DOI: 10.1016/b978-1-4557-0738-6.00013-9.
- Peters-Lawrence M, Bell M, Hsu L, Osunkwo I, Seaman P, Blackwood M, Guillaume E, Bellevue R, Krishnamurti L, Smith W, Dampier C, Minniti C, Network F. Clinical trial implementation and recruitment: Lessons learned from the early closure of a randomized clinical trial. Contemporary Clinical Trials 2011, 33: 291-297. PMID: 22155024, PMCID: PMC3577351, DOI: 10.1016/j.cct.2011.11.018.
- Sachdev V, Kato G, Gibbs J, Barst R, Machado R, Nouraie M, Hassell K, Little J, Schraufnagel D, Krishnamurti L, Novelli E, Girgis R, Morris C, Rosenzweig E, Badesch D, Lanzkron S, Castro O, Taylor J, Hannoush H, Goldsmith J, Gladwin M, Gordeuk V. Echocardiographic Markers of Elevated Pulmonary Pressure and Left Ventricular Diastolic Dysfunction Are Associated With Exercise Intolerance in Adults and Adolescents With Homozygous Sickle Cell Anemia in the United States and United Kingdom. Circulation 2011, 124: 1452-1460. PMID: 21900080, PMCID: PMC3183314, DOI: 10.1161/circulationaha.111.032920.
- Long K, Thomas S, Grubs R, Gettig E, Krishnamurti L. Attitudes and Beliefs of African‐Americans Toward Genetics, Genetic Testing, and Sickle Cell Disease Education and Awareness. Journal Of Genetic Counseling 2011, 20: 572-592. PMID: 21748660, DOI: 10.1007/s10897-011-9388-3.
- Kladny B, Williams A, Gupta A, Gettig E, Krishnamurti L. Genetic counseling following the detection of hemoglobinopathy trait on the newborn screen is well received, improves knowledge, and relieves anxiety. Genetics In Medicine 2011, 13: 658-661. PMID: 21546841, DOI: 10.1097/gim.0b013e31821435f7.
- Machado R, Barst R, Yovetich N, Hassell K, Kato G, Gordeuk V, Gibbs J, Little J, Schraufnagel D, Krishnamurti L, Girgis R, Morris C, Rosenzweig E, Badesch D, Lanzkron S, Onyekwere O, Castro O, Sachdev V, Waclawiw M, Woolson R, Goldsmith J, Gladwin M, Investigators and Patients O. Hospitalization for pain in patients with sickle cell disease treated with sildenafil for elevated TRV and low exercise capacity. Blood 2011, 118: 855-864. PMID: 21527519, PMCID: PMC3148167, DOI: 10.1182/blood-2010-09-306167.
- Aloe A, Krishnamurti L, Kladny B. Testing of Collegiate Athletes for Sickle Cell Trait: What We, as Genetic Counselors Should Know. Journal Of Genetic Counseling 2011, 20: 337-340. PMID: 21503822, DOI: 10.1007/s10897-011-9366-9.
- Gladwin M, Kato G, Weiner D, Onyekwere O, Dampier C, Hsu L, Hagar R, Howard T, Nuss R, Okam M, Tremonti C, Berman B, Villella A, Krishnamurti L, Lanzkron S, Castro O, Gordeuk V, Coles W, Peters-Lawrence M, Nichols J, Hall M, Hildesheim M, Blackwelder W, Baldassarre J, Casella J, Investigators F. Nitric Oxide for Inhalation in the Acute Treatment of Sickle Cell Pain Crisis: A Randomized Controlled Trial. JAMA: The Journal Of The American Medical Association 2011, 305: 893-902. PMID: 21364138, PMCID: PMC3403835, DOI: 10.1001/jama.2011.235.
- Hematopoietic Stem Cell Transplantation for Hemoglobinopathies: Current Practice and Emerging TrendsSmiers F, Krishnamurti L, Lucarelli G. Hematopoietic Stem Cell Transplantation for Hemoglobinopathies: Current Practice and Emerging Trends. Pediatric Clinics Of North America 2010, 57: 181-205. PMID: 20307718, DOI: 10.1016/j.pcl.2010.01.003.
- Buchanan G, Vichinsky E, Krishnamurti L, Shenoy S. Severe Sickle Cell Disease—Pathophysiology and Therapy. Transplantation And Cellular Therapy 2009, 16: s64-s67. PMID: 19819341, PMCID: PMC2832723, DOI: 10.1016/j.bbmt.2009.10.001.
- Rao V, Price S, Perkins K, Aldridge P, Tretler J, Davis J, Dale J, Gill F, Hartman K, Stork L, Gnarra D, Krishnamurti L, Newburger P, Puck J, Fleisher T. Use of rituximab for refractory cytopenias associated with autoimmune lymphoproliferative syndrome (ALPS). Pediatric Blood & Cancer 2009, 52: 847-852. PMID: 19214977, PMCID: PMC2774763, DOI: 10.1002/pbc.21965.
- Krishnamurti L, Kharbanda S, Biernacki M, Zhang W, Baker K, Wagner J, Wu C. Stable Long-Term Donor Engraftment following Reduced-Intensity Hematopoietic Cell Transplantation for Sickle Cell Disease. Transplantation And Cellular Therapy 2008, 14: 1270-1278. PMID: 18940682, DOI: 10.1016/j.bbmt.2008.08.016.
- Krishnamurti L. Iron-Deficiency Anemia. 2008, 2201-2211. DOI: 10.1542/9781581106411-9-ch287.
- Krishnamurti L, Bunn H, Williams A, Tolar J. Hematopoietic Cell Transplantation for Hemoglobinopathies. Current Problems In Pediatric And Adolescent Health Care 2008, 38: 6-18. PMID: 18068866, DOI: 10.1016/j.cppeds.2007.10.002.
- Krishnamurti L, Gupta D. Hematopoietic stem cell transplantation for hemoglobinopathies: Progress and prospects. Indian Journal Of Medical And Paediatric Oncology 2008, 29: 39-48. DOI: 10.4103/0971-5851.51444.
- Adamkiewicz T, Szabolcs P, Haight A, Baker K, Staba S, Kedar A, Chiang K, Krishnamurti L, Boyer M, Kurtzberg J, Wagner J, Wingard J, Yeager A. Unrelated cord blood transplantation in children with sickle cell disease: Review of four‐center experience. Pediatric Transplantation 2007, 11: 641-644. PMID: 17663687, DOI: 10.1111/j.1399-3046.2007.00725.x.
- Gustafson S, Gettig E, Watt-Morse M, Krishnamurti L. Health beliefs among African American women regarding genetic testing and counseling for sickle cell disease. Genetics In Medicine 2007, 9: 303-310. PMID: 17505208, DOI: 10.1097/gim.0b013e3180534282.
- Krishnamurti L. Hematopoietic cell transplantation for sickle cell disease: state of the art. Expert Opinion On Biological Therapy 2007, 7: 161-172. PMID: 17250455, DOI: 10.1517/14712598.7.2.161.
- Krishnamurti L. HEMATOPOIETIC CELL TRANSPLANTATION: A Curative Option for Sickle Cell Disease. Pediatric Hematology And Oncology 2007, 24: 569-575. PMID: 18092247, DOI: 10.1080/08880010701640531.
- LaRosa C, McMullen L, Bakdash S, Ellis D, Krishnamurti L, Wu H, Moritz M. Acute renal failure from xanthine nephropathy during management of acute leukemia. Pediatric Nephrology 2006, 22: 132-135. PMID: 17039332, DOI: 10.1007/s00467-006-0287-z.
- Patik M, Phillips L, Kladny B, Captain A, Gettig E, Krishnamurti L. Structured telephone‐based outreach using nonmedical personnel can improve adherence to comprehensive care in families of children with sickle cell disease. American Journal Of Hematology 2006, 81: 462-464. PMID: 16680738, DOI: 10.1002/ajh.20605.
- Krishnamurti L, Lanford L, Munoz R. Life threatening parvovirus B19 and herpes simplex virus associated acute myocardial dysfunction in a child with homozygous sickle cell disease. Pediatric Blood & Cancer 2006, 49: 1019-1021. PMID: 16700044, DOI: 10.1002/pbc.20855.
- Ambrusko S, Gunawardena S, Sakara A, Windsor B, Lanford L, Michelson P, Krishnamurti L. Elevation of tricuspid regurgitant jet velocity, a marker for pulmonary hypertension in children with sickle cell disease. Pediatric Blood & Cancer 2006, 47: 907-913. PMID: 16496290, DOI: 10.1002/pbc.20791.
- Krishnamurti L. Commentary on “Identification of Unrelated Cord Blood Units for Hematopoietic Stem Cell Transplantation in Children With Sickle Cell Disease”. Journal Of Pediatric Hematology/Oncology 2006, 28: 1-3. PMID: 16394884, DOI: 10.1097/01.mph.0000196448.99446.0a.
- Kladny B, Gettig E, Krishnamurti L. Systematic follow-up and case management of the abnormal newborn screen can improve acceptance of genetic counseling for sickle cell or other hemoglobinopathy trait. Genetics In Medicine 2005, 7: 139-142. PMID: 15714082, DOI: 10.1097/01.gim.0000153662.88425.68.
- Wilson R, Krishnamurti L, Kamat D. Management of Sickle Cell Disease in Primary Care. Clinical Pediatrics 2003, 42: 753-761. PMID: 14686547, DOI: 10.1177/000992280304200901.
- Krishnamurti L, Abel S, Maiers M, Flesch S. Availability of unrelated donors for hematopoietic stem cell transplantation for hemoglobinopathies. Bone Marrow Transplantation 2003, 31: 547-550. PMID: 12692619, DOI: 10.1038/sj.bmt.1703887.
- Pastore Y, Jelinek J, Ang S, Guan Y, Liu E, Jedlickova K, Krishnamurti L, Prchal J. Mutations in the VHL gene in sporadic apparently congenital polycythemia. Blood 2002, 101: 1591-1595. PMID: 12393546, DOI: 10.1182/blood-2002-06-1843.
- Zapzalka D, Krishnamurti L, Manivel J, DiSandro M. Lymphangioma of the Renal Capsule. Journal Of Urology 2002, 168: 220. PMID: 12050546, DOI: 10.1016/s0022-5347(05)64895-1.
- Krishnamurti L, Neglia J, Nagarajan R, Berry S, Lohr J, Hirsch B, White J. Paris‐Trousseau syndrome platelets in a child with Jacobsen's syndrome. American Journal Of Hematology 2001, 66: 295-299. PMID: 11279643, DOI: 10.1002/ajh.1061.
- Krishnamurti L, Blazar B, Wagner J. Bone Marrow Transplantation without Myeloablation for Sickle Cell Disease. The New England Journal Of Medicine 2001, 344: 68. PMID: 11187121, DOI: 10.1056/nejm200101043440119.
- Krishnamurti L. Few Reports of Hemoglobin E/β-Thalassemia in Northeast India: Underdiagnosis or Complete Exclusion of β-Thalassemia by Hemoglobin E. Journal Of Pediatric Hematology/Oncology 2000, 22: 558-563. PMID: 11132230, DOI: 10.1097/00043426-200011000-00023.
- Krishnamurti L, Neglia J, Nagarajan R, Berry S, Hirsch B, Matsunaga A, White J. Paris-Trousseau platelets: a manifestation of Jacobsen syndrome. Journal Of Pediatric Hematology/Oncology 2000, 22: 373. DOI: 10.1097/00043426-200007000-00046.
- Recurrence of EBV associated, high-grade, post-transplant lymphoma presenting as acute renal failureLewis V, Dahl J, Braunlin E, Steiner M, Perentesis J, Neglia J, Krishnamurti L. Recurrence of EBV associated, high-grade, post-transplant lymphoma presenting as acute renal failure. Journal Of Pediatric Hematology/Oncology 2000, 22: 378-379. DOI: 10.1097/00043426-200007000-00065.
- Krishnamurti L, Blazar B, Grossi M, Abel S, Vichinsky E, Lubin B, Wagner J. Treatment of sickle cell disease (SCD) by an allogeneic hematopoietic stem cell transplantation (HSCT) using a non-myeloablative preparative regimen. Journal Of Pediatric Hematology/Oncology 2000, 22: 387. DOI: 10.1097/00043426-200007000-00093.
- Weigel B, Lasky A, Krishnamurti L, Perentesis J, Neglia J, Foker J, Key N, Edson R, Steiner M. #432 Danaparoid (orgaran) anti-coagulation of pediatric patients with heparin-induced thrombocytopenia (HIT). Journal Of Pediatric Hematology/Oncology 1999, 21: 457. DOI: 10.1097/00043426-199909000-00035.
- Weigel B, Lasky A, Krishnamurti L, Perentesis J, Neglia J, Foker J, Key N, Edson R, Steiner M. #432 Danaparoid (orgaran) anticoagulation of pediatric patients with heparininduced thrombocytopenia (HIT). Journal Of Pediatric Hematology/Oncology 1999, 21: 327. DOI: 10.1097/00043426-199907000-00093.
- KRISHNAMURTI L, LITTLE J. Homozygous Hemoglobin Constant Spring with Normal Electrophoresis: A Possible Cause for Under‐Diagnosis. Annals Of The New York Academy Of Sciences 1998, 850: 415-419. PMID: 9668571, DOI: 10.1111/j.1749-6632.1998.tb10508.x.
- Krishnamurti L, Chui D, Dallaire M, LeRoy B, Waye J, Perentesis J. Coinheritance of α-thalassemia-1 and hemoglobin E/β0-thalassemia: Practical implications for neonatal screening and genetic counseling. The Journal Of Pediatrics 1998, 132: 863-865. PMID: 9602201, DOI: 10.1016/s0022-3476(98)70319-1.
- Pediatric Specialty CenterSmilow Cancer Hospital at Yale New Haven35 Park Street, Wing North Pavillion Fl 7New Haven, CT 06511
- Pediatric Specialty CenterTrumbull Pediatric Specialty Center5520 Park Avenue, Ste 600Trumbull, CT 06611
- Pediatric Specialty CenterOld Saybrook Medical Center633 Middlesex Turnpike, Ste 110Old Saybrook, CT 06475
Biography
Lakshmanan Krishnamurti, MD, is chief of Pediatric Hematology and Oncology and specializes in bone marrow transplant and treating sickle cell disease and other inherited red blood cell disorders.
Dr. Krishnamurti says he decided in second grade that he would become a physician.
“I read something about doctors helping people and I just knew that was what I was going to do. Nobody ever dissuaded me,” he says.
Pediatrics, he adds, was an obvious fit because of the joy he finds working with children.
“Children have such an original view of the world. They aren’t weighed down by burdens, and they see life as an unending horizon in front of them. They are confident in their perspective and they are unfiltered,” he says. “You can look at a child and know if they are doing well or not.”
Still, it takes a special set of communication skills to draw them out, Dr. Krishnamurti says. “Children often have concrete anxieties and fears. They aren’t worried about global warming, but if something is going to hurt and if you are someone they can trust,” he says. “They might not have the eloquence to say that, but you can read their body language.”
To connect with children and their families, Dr. Krishnamurti says he makes a point to sit down when he enters the exam room. Naturally, much of his job also entails working with family members, too.
“You have to be at ease for people to be at ease with you. And you have to radiate that they have your time and attention,” he says. “And then I talk to the child right away, on their level. The most important aspect of these encounters is reassurance. It can be a minor thing, but you can’t reassure people enough.”
Dr. Krishnamurti says he was drawn to hematology because it combines pathology, procedures, and the cognitive aspects of medicine. “I am fascinated by red cell disorders and genetic disorders,” he says. “And I love working with underserved populations, which is how I got interested in sickle cell disease. I became acutely aware of the burden of this disease and the stigma of all genetic diseases, as well as the hopelessness and despair people can feel around them.
His research focuses on curative therapies, including gene therapy and how people make medical decisions, including what motivates them to take (or not take) medications, particularly with transplant patients.
Titles
- Professor of Pediatrics (Hematology/Oncology)
- Chief, Pediatric Hematology and Oncology
Education & Training
- MDUniversity of Poona, Armed Forces Medical College (1980)
Additional Information
- AB of Pediatrics, Pediatric Hematology-Oncology (2000)
- AB of Pediatrics, Pediatrics (1998)
- Chetlapalli K, Ito S, Ng DQ, Sra MS, Wang D, Krumholz H, Krishnamurti L, Pandya A, Goshua G. Haploidentical transplant, gene therapy, and standard care in sickle cell disease: a cost-effectiveness analysis. Blood Journal 2026, blood.2025032290. DOI: 10.1182/blood.2025032290.
- Jagtiani A, Hawk A, Sinha C, Gillespie S, Mirbeyk M, Burke R, Ifendu N, Reese S, Howard V, Boguslawski S, Thompson O, Ikkurthy N, El Rassi F, Smith W, Krishnamurti L, Sil S, Bakshi N. A prospective study of high-impact chronic pain in sickle cell disease: the Sickle Pain-Related Impact (SPiRIt) study. Pain 2026 PMID: 42017907, DOI: 10.1097/j.pain.0000000000003956.
- Sharma A, Abraham A, Bhatia M, Cancio M, Chaudhury S, Corbacioglu S, Guilcher G, Gupta A, Hanna R, Heeney M, John T, Krishnamurti L, LaBelle J, Rangarajan H, Shenoy S, Stenger E, Strunk C, Fitzhugh C. G‐CSF for Mobilizing CD34+ Cells in Individuals With SCD: A Word of Caution. American Journal Of Hematology 2026 PMID: 41705621, DOI: 10.1002/ajh.70235.
- Krishnamurti L, Olafimihan A, Hsu L. Informed shared decision-making or rigid eligibility and exclusion criteria for gene therapy for sickle cell disease? Blood Advances 2026, 10: 608-617. PMID: 41092461, PMCID: PMC12865566, DOI: 10.1182/bloodadvances.2025017015.
- Inam Z, Stenger E, John T, Liu K, Gillespie S, Shah R, Chellapandian D, Bhatia M, Chaudhury S, Eckrich M, Guilcher G, Hendrickson J, Hulbert M, Jaroscak J, Kasow K, Camacho‐Bydume C, Ngwube A, Olson T, Rangarajan H, Horan J, Krishnamurti L, Shenoy S, Abraham A, Nickel R. RBC Alloimmunization Impacts Pediatric Sickle Cell Disease Transplant Outcomes and Transfusion Burden: A STAR Registry Report. American Journal Of Hematology 2026, 101: 756-767. PMID: 41524608, DOI: 10.1002/ajh.70200.
- Jamwal S, Calhoun C, Mohanty S, Montgomery R, Krishnamurti L, Shaw A, Yildirim I. Unravelling the Immunological Enigma of Sickle Cell Disease: Current Understanding and Future Directions. Immunology 2025, 177: 445-456. PMID: 41387179, PMCID: PMC12826409, DOI: 10.1111/imm.70080.
- John T, Krishnamurti L. The Pediatric Clinician’s Approach to Referring Children and Adolescents with Sickle Cell Disease for Potentially Curative Therapies. Pediatric Clinics Of North America 2025, 73: 203-218. PMID: 41207739, DOI: 10.1016/j.pcl.2025.08.018.
- Chandrasekar R, Kane M, Krishnamurti L. Machine-Learning Predictive Tool for the Individualized Prediction of Outcomes of Hematopoietic Cell Transplantation for Sickle Cell Disease: Registry-Based Study. JMIR AI 2025, 4: e64519. PMID: 40952774, PMCID: PMC12435087, DOI: 10.2196/64519.
- Shenoy S, Kanter J, Kassim A, Fitzhugh C, Stenger E, Bhatia M, Pecker L, Krishnamurti L, King A. A road map for uniform, comprehensive long-term follow-up after curative therapy for sickle cell disease. Blood Advances 2025, 9: 3090-3103. PMID: 39993235, PMCID: PMC12432986, DOI: 10.1182/bloodadvances.2024013953.
- Shah N, Ngwube A, Suresh T, Sowa A, Abraham A, Anderson E, Andreansky M, Bhatia M, Chaudhury S, Cuvelier G, Dalal J, Grimley M, Jacobsohn D, Kamani N, Krajewski J, Krishnamurti L, Saini S, Skiles J, Shenoy S. Impact of Abatacept Inclusive Graft-Versus-Host Disease Prophylaxis in Pediatric Stem Cell Transplantation for Hemoglobinopathy. Transplantation And Cellular Therapy 2025, 31: 826.e1-826.e10. PMID: 40543708, DOI: 10.1016/j.jtct.2025.06.015.
- Prior D, Liang J, Deng Y, Shah N, Flagg A, Krishnamurti L. Comparison of Regimens Used for Allogeneic Matched Related Donor Hematopoietic Cell Transplantation for Sickle Cell Disease. Transplantation And Cellular Therapy 2025, 31: 594.e1-594.e13. PMID: 40379050, DOI: 10.1016/j.jtct.2025.05.004.
- Walters M, Eapen M, Liu Y, El Rassi F, Waller E, Levine J, Strouse J, Antin J, Parikh S, Bakshi N, Dampier C, Jaroscak J, Bergmann S, Wong T, Kota V, Pace B, Lekakis L, Lulla P, Nickel R, Kasow K, Popat U, Smith W, Yu L, DiFronzo N, Geller N, Kamani N, Klings E, Hassell K, Mendizabal A, Sullivan K, Neuberg D, Krishnamurti L. Hematopoietic cell transplant compared with standard care in adolescents and young adults with sickle cell disease. Blood Advances 2025, 9: 955-965. PMID: 39471440, PMCID: PMC11907447, DOI: 10.1182/bloodadvances.2024013926.
- Huang S, Gillespie S, Chou E, Liu K, Jagtiani A, Krishnamurti L, Bakshi N. Clinical phenotype of high-impact chronic pain in sickle cell disease at consultation for hematopoietic cell transplant. Journal Of Sickle Cell Disease 2025, 2: yoaf028. PMID: 41024866, PMCID: PMC12476911, DOI: 10.1093/jscdis/yoaf028.
- Gupta K, Krishnamurti L, Jain D. Sickle cell disease in India: the journey and hope for the future. Hematology 2024, 2024: 1-9. PMID: 39644008, PMCID: PMC11665512, DOI: 10.1182/hematology.2024000678.
- Gupta V, Krishnamurti L. Haematopoietic stem-cell transplantation for sickle cell disease in low-income and middle-income countries: the experience in India. The Lancet Haematology 2024, 11: e812-e813. PMID: 39482019, DOI: 10.1016/s2352-3026(24)00272-2.
- Lessard S, Rimmelé P, Ling H, Moran K, Vieira B, Lin Y, Rajani G, Hong V, Reik A, Boismenu R, Hsu B, Chen M, Cockroft B, Uchida N, Tisdale J, Alavi A, Krishnamurti L, Abedi M, Galeon I, Reiner D, Wang L, Ramezi A, Rendo P, Walters M, Levasseur D, Peters R, Harris T, Hicks A. Zinc finger nuclease-mediated gene editing in hematopoietic stem cells results in reactivation of fetal hemoglobin in sickle cell disease. Scientific Reports 2024, 14: 24298. PMID: 39414860, PMCID: PMC11484757, DOI: 10.1038/s41598-024-74716-7.
- Arnold S, Bakshi N, Ross D, Smith C, Sinha C, Veludhandi A, Dutreuil V, Bai S, Meacham L, Guilcher G, Bhatia M, Abraham A, Kasow K, Haight A, Rassi F, Stenger E, Lipscomb J, Krishnamurti L. Long‐term quality of life after hematopoietic cell transplant for sickle cell disease in childhood: A STELLAR interim analysis. American Journal Of Hematology 2024, 99: 2037-2040. PMID: 39105410, DOI: 10.1002/ajh.27436.
- George S, Veludhandi A, Xiang Y, Liu K, Stenger E, Arnold S, Mehta A, Schirmer D, Spencer J, Guilcher G, Bhatia M, Abraham A, Gomez-Lobo V, Krishnamurti L, Meacham L. Reproductive Health Assessment and Reports of Fertility Counseling in Pediatric and Adolescent Patients with Sickle Cell Disease After Hematopoietic Cell Transplantation. Transplantation And Cellular Therapy 2024, 30: 912.e1-912.e13. PMID: 38972510, PMCID: PMC11344653, DOI: 10.1016/j.jtct.2024.06.029.
- Jagtiani A, Chou E, Gillespie S, Liu K, Krishnamurti L, McClish D, Smith W, Bakshi N. High-impact chronic pain in sickle cell disease: insights from the Pain in Sickle Cell Epidemiology Study (PiSCES). Pain 2024, 165: 2364-2369. PMID: 38787626, PMCID: PMC11404329, DOI: 10.1097/j.pain.0000000000003262.
- Jain D, Gupta M, Madkaikar M, Jena R, Khargekar N, Saraf S, Krishnamurti L, Gupta K. Sickle cell disease in India: current status and progress. The Lancet Haematology 2024, 11: e322-e323. PMID: 38701819, DOI: 10.1016/s2352-3026(24)00109-1.
- Krishnamurti L, Liang J, He Z, Deng Y, Nallagatla V, Hamidi R, Flagg A, Shah N. Incidence and risk factors of pain crisis after hematopoietic cell transplantation for sickle cell disease. Blood Advances 2024, 8: 1908-1919. PMID: 38324722, PMCID: PMC11021890, DOI: 10.1182/bloodadvances.2023010749.
- Eapen M, Kou J, Andreansky M, Bhatia M, Brochstein J, Chaudhury S, Haight A, Haines H, Jacobsohn D, Jaroscak J, Kasow K, Krishnamurti L, Levine J, Leung K, Margolis D, Yu L, Horowitz M, Kamani N, Walters M, Shenoy S. Long‐term outcomes after unrelated donor transplantation for severe sickle cell disease on the BMT CTN 0601 trial. American Journal Of Hematology 2024, 99: 785-788. PMID: 38343182, PMCID: PMC10947844, DOI: 10.1002/ajh.27251.
- Ito S, Pandya A, Hauser R, Krishnamurti L, Stites E, Tormey C, Krumholz H, Hendrickson J, Goshua G. Decreasing alloimmunization‐specific mortality in sickle cell disease in the United States: Cost‐effectiveness of a shared transfusion resource. American Journal Of Hematology 2024, 99: 570-576. PMID: 38279581, DOI: 10.1002/ajh.27211.
- Goshua G, Calhoun C, Ito S, James L, Luviano A, Krishnamurti L, Pandya A. Distributional Cost-Effectiveness of Equity-Enhancing Gene Therapy in Sickle Cell Disease in the United States. Annals Of Internal Medicine 2023, 176: 779-787. PMID: 37247420, PMCID: PMC10370480, DOI: 10.7326/m22-3272.
- Meacham L, George S, Veludhandi A, Pruett M, Haight A, Arnold S, Elchuri S, Stenger E, Krishnamurti L. Female Reproductive Health Outcomes after Hematopoietic Cell Transplantation for Sickle Cell Disease: Is Reduced Intensity Better Than Myeloablative Conditioning? Transplantation And Cellular Therapy 2023, 29: 531.e1-531.e4. PMID: 37169288, DOI: 10.1016/j.jtct.2023.05.004.
- Sinha C, Meacham L, Bakshi N, Ross D, Krishnamurti L. Parental perspective on the risk of infertility and fertility preservation options for children and adolescents with sickle cell disease considering hematopoietic stem cell transplantation. Pediatric Blood & Cancer 2023, 70: e30276-e30276. PMID: 37051746, PMCID: PMC10544372, DOI: 10.1002/pbc.30276.
- Chiang K, Gupta A, Sundd P, Krishnamurti L. Thrombo-Inflammation in COVID-19 and Sickle Cell Disease: Two Faces of the Same Coin. Biomedicines 2023, 11: 338. PMID: 36830874, PMCID: PMC9953430, DOI: 10.3390/biomedicines11020338.
- Eapen M, Brazauskas R, Williams D, Walters M, St Martin A, Jacobs B, Antin J, Bona K, Chaudhury S, Coleman-Cowger V, DiFronzo N, Esrick E, Field J, Fitzhugh C, Kanter J, Kapoor N, Kohn D, Krishnamurti L, London W, Pulsipher M, Talib S, Thompson A, Waller E, Wun T, Horowitz M. Secondary Neoplasms After Hematopoietic Cell Transplant for Sickle Cell Disease. Journal Of Clinical Oncology 2023, 41: 2227-2237. PMID: 36623245, PMCID: PMC10448940, DOI: 10.1200/jco.22.01203.
- Bakshi N, Astles R, Chou E, Hurreh A, Sil S, Sinha C, Sanders K, Peddineni M, Gillespie S, Keesari R, Krishnamurti L. Multimodal phenotyping and correlates of pain following hematopoietic cell transplant in children with sickle cell disease. Pediatric Blood & Cancer 2022, 70: e30046-e30046. PMID: 36322607, PMCID: PMC9820671, DOI: 10.1002/pbc.30046.
- Stenger E, Xiang Y, Wetzel M, Gillespie S, Chellapandian D, Shah R, Arnold S, Bhatia M, Chaudhury S, Eckrich M, Kanter J, Kasow K, Krajewski J, Nickel R, Ngwube A, Olson T, Rangarajan H, Wobma H, Guilcher G, Horan J, Krishnamurti L, Shenoy S, Abraham A. Long-Term Organ Function After HCT for SCD: A Report From the Sickle Cell Transplant Advocacy and Research Alliance. Transplantation And Cellular Therapy 2022, 29: 47.e1-47.e10. PMID: 36273784, DOI: 10.1016/j.jtct.2022.10.012.
- Krishnamurti L, Neuberg D, Sullivan K, Smith S, Eapen M, Walters M. Enrollment Lessons from a Biological Assignment Study of Marrow Transplantation versus Standard Care for Adolescents and Young Adults with Sickle Cell Disease: Considerations for Future Gene and Cellular Therapy Trials. Transplantation And Cellular Therapy 2022, 29: 217-221. PMID: 36270432, PMCID: PMC10539686, DOI: 10.1016/j.jtct.2022.10.008.
- Quarmyne M, Ross D, Sinha C, Bakshi N, Boudreaux J, Krishnamurti L. Decision-making about gene therapy in transfusion dependent thalassemia. BMC Pediatrics 2022, 22: 536. PMID: 36085025, PMCID: PMC9461218, DOI: 10.1186/s12887-022-03598-3.
- Krishnamurti L, Arnold S, Haight A, Abraham A, Guilcher G, John T, Bakshi N, Shenoy S, Syrjala K, Martin P, Chaudhury S, Eames G, Olowoselu O, Hsieh M, De La Fuente J, Kasow K, Stenger E, Mertens A, El-Rassi F, Lane P, Shaw B, Meacham L, Archer D. Sickle Cell Transplantation Evaluation of Long-term and Late Effects Registry (STELLAR) to Compare Long-term Outcomes After Hematopoietic Cell Transplantation to Those in Siblings Without Sickle Cell Disease and in Nontransplanted Individuals With Sickle Cell Disease: Design and Feasibility Study. JMIR Research Protocols 2022, 11: e36780. PMID: 35793124, PMCID: PMC9301564, DOI: 10.2196/36780.
- Rodgers-Melnick S, Lin L, Gam K, Souza de Santana Carvalho E, Jenerette C, Rowland D, Little J, Dusek J, Bakshi N, Krishnamurti L. Effects of Music Therapy on Quality of Life in Adults with Sickle Cell Disease (MUSIQOLS): A Mixed Methods Feasibility Study [Erratum]. Journal Of Pain Research 2022, 15: 1123-1124. PMID: 35469252, PMCID: PMC9034844, DOI: 10.2147/jpr.s370799.
- Day J, Takemoto C, Sharathkumar A, Makhani S, Gupta A, Bitner S, Josephson C, Bloch E, Tobian A, Krishnamurti L, Goel R. Associated comorbidities, healthcare utilization & mortality in hospitalized patients with haemophilia in the United States: Contemporary nationally representative estimates. Haemophilia 2022, 28: 532-541. PMID: 35412659, PMCID: PMC9540439, DOI: 10.1111/hae.14557.
- Rodgers-Melnick S, Lin L, Gam K, de Santana Carvalho E, Jenerette C, Rowland D, Little J, Dusek J, Bakshi N, Krishnamurti L. Effects of Music Therapy on Quality of Life in Adults with Sickle Cell Disease (MUSIQOLS): A Mixed Methods Feasibility Study. Journal Of Pain Research 2022, 15: 71-91. PMID: 35046718, PMCID: PMC8760983, DOI: 10.2147/jpr.s337390.
- Chiang K, Rizk J, Nelson D, Krishnamurti L, Subbian S, Imig J, Khan I, Reddy S, Gupta A. Ramatroban for chemoprophylaxis and treatment of COVID-19: David takes on Goliath. Expert Opinion On Therapeutic Targets 2022, 26: 13-28. PMID: 35068281, PMCID: PMC10119876, DOI: 10.1080/14728222.2022.2031975.
- Krishnamurti L. Hematopoietic cell transplantation for sickle cell disease: updates and future directions. Hematology 2021, 2021: 181-189. PMID: 34889368, PMCID: PMC8791142, DOI: 10.1182/hematology.2021000251.
- Veludhandi A, Ross D, Sinha C, McCracken C, Bakshi N, Krishnamurti L. A Decision Support Tool for Allogeneic Hematopoietic Stem Cell Transplantation for Children With Sickle Cell Disease: Acceptability and Usability Study. JMIR Formative Research 2021, 5: e30093. PMID: 34709190, PMCID: PMC8587189, DOI: 10.2196/30093.
- Katoch D, Krishnamurti L. Assessing Patient Preferences for Treatment Options for Pediatric Sickle Cell Disease: A Critical Review of Quantitative and Qualitative Studies. Patient Preference And Adherence 2021, 15: 2221-2229. PMID: 34629865, PMCID: PMC8493010, DOI: 10.2147/ppa.s264918.
- Bakshi N, Gillespie S, McClish D, McCracken C, Smith W, Krishnamurti L. Intraindividual pain variability and phenotypes of pain in sickle cell disease: a secondary analysis from the Pain in Sickle Cell Epidemiology Study. Pain 2021, 163: 1102-1113. PMID: 34538841, PMCID: PMC9100443, DOI: 10.1097/j.pain.0000000000002479.
- Mupfudze T, Meyer C, Preussler J, Mau L, Bolon Y, Steinert P, Arnold S, Saber W, Krishnamurti L. Hematopoietic Cell Transplantation Outcomes among Medicaid and Privately Insured Patients with Sickle Cell Disease. Transplantation And Cellular Therapy 2021, 27: 685.e1-685.e8. PMID: 33895405, PMCID: PMC8680220, DOI: 10.1016/j.jtct.2021.04.009.
- Bakshi N, Cooley A, Ross D, Hawkins L, Sullivan M, Astles R, Sinha C, Katoch D, Peddineni M, Gee B, Lane P, Krishnamurti L. A pilot study of the acceptability, feasibility and safety of yoga for chronic pain in sickle cell disease. Complementary Therapies In Medicine 2021, 59: 102722. PMID: 33892094, PMCID: PMC8284565, DOI: 10.1016/j.ctim.2021.102722.
- Krishnamurti L. Gaps in Medicaid Coverage and Financial Toxicity: A Health Disparity in Hematopoietic Cell Transplantation for Sickle Cell Disease. Transplantation And Cellular Therapy 2021, 27: 284-285. PMID: 33836866, DOI: 10.1016/j.jtct.2021.03.016.
- Krishnamurti L. Hematopoietic Cell Transplantation for Sickle Cell Disease. Frontiers In Pediatrics 2021, 8: 551170. PMID: 33469520, PMCID: PMC7813811, DOI: 10.3389/fped.2020.551170.
- Sheshadri V, Shabeer P, Santhirapala V, Jayaram A, Krishnamurti L, Menon N. Mortality in sickle cell disease: A population‐based study in an aboriginal community in the Gudalur Valley, Nilgiris, Tamil Nadu, India. Pediatric Blood & Cancer 2020, 68: e28875. PMID: 33381914, DOI: 10.1002/pbc.28875.
- Ross D, Sinha C, Bakshi N, Krishnamurti L. Educational needs of patients and caregivers living with sickle cell disease results in development of web‐based patient decision aid. Journal Of Advanced Nursing 2020, 77: 1432-1441. PMID: 33277763, DOI: 10.1111/jan.14704.
- Sinha C, Bakshi N, Ross D, Loewenstein G, Krishnamurti L. Primary caregiver decision‐making in hematopoietic cell transplantation and gene therapy for sickle cell disease. Pediatric Blood & Cancer 2020, 68: e28749-e28749. PMID: 33034129, PMCID: PMC8246626, DOI: 10.1002/pbc.28749.
- Tisdale J, Pierciey F, Bonner M, Thompson A, Krishnamurti L, Mapara M, Kwiatkowski J, Shestopalov I, Ribeil J, Huang W, Asmal M, Kanter J, Walters M. Safety and feasibility of hematopoietic progenitor stem cell collection by mobilization with plerixafor followed by apheresis vs bone marrow harvest in patients with sickle cell disease in the multi‐center HGB‐206 trial. American Journal Of Hematology 2020, 95: e239-e242. PMID: 32401372, DOI: 10.1002/ajh.25867.
- Bakshi N, Katoch D, Sinha C, Ross D, Quarmyne M, Loewenstein G, Krishnamurti L. Assessment of Patient and Caregiver Attitudes and Approaches to Decision-Making Regarding Bone Marrow Transplant for Sickle Cell Disease. JAMA Network Open 2020, 3: e206742. PMID: 32469414, PMCID: PMC7260617, DOI: 10.1001/jamanetworkopen.2020.6742.
- Hawkins L, Sinha C, Ross D, Yee M, Quarmyne M, Krishnamurti L, Bakshi N. Patient and family experience with chronic transfusion therapy for sickle cell disease: A qualitative study. BMC Pediatrics 2020, 20: 172. PMID: 32305060, PMCID: PMC7165370, DOI: 10.1186/s12887-020-02078-w.
- Krishnamurti L. Should young children with sickle cell disease and an available human leukocyte antigen identical sibling donor be offered hematopoietic cell transplantation? Hematology/Oncology And Stem Cell Therapy 2020, 13: 53-57. PMID: 32202246, DOI: 10.1016/j.hemonc.2019.12.008.
- Matthie N, Jenerette C, Gibson A, Paul S, Higgins M, Krishnamurti L. Prevalence and predictors of chronic pain intensity and disability among adults with sickle cell disease. Health Psychology Open 2020, 7: 2055102920917250. PMID: 32426150, PMCID: PMC7218472, DOI: 10.1177/2055102920917250.
- Stenger E, Shenoy S, Krishnamurti L. How I treat sickle cell disease with hematopoietic cell transplantation. Blood 2019, 134: 2249-2260. PMID: 31697818, PMCID: PMC6923666, DOI: 10.1182/blood.2019000821.
- Farrell A, Panepinto J, Desai A, Kassim A, Lebensburger J, Walters M, Bauer D, Blaylark R, DiMichele D, Gladwin M, Green N, Hassell K, Kato G, Klings E, Kohn D, Krishnamurti L, Little J, Makani J, Malik P, McGann P, Minniti C, Morris C, Odame I, Oneal P, Setse R, Sharma P, Shenoy S. End points for sickle cell disease clinical trials: renal and cardiopulmonary, cure, and low-resource settings. Blood Advances 2019, 3: 4002-4020. PMID: 31809537, PMCID: PMC6963248, DOI: 10.1182/bloodadvances.2019000883.
- Krishnamurti L, Ross D, Sinha C, Leong T, Bakshi N, Mittal N, Veludhandi D, Pham A, Taneja A, Gupta K, Nwanze J, Matthews A, Joshi S, Olivieri V, Arjunan S, Okonkwo I, Lukombo I, Lane P, Bakshi N, Loewenstein G. Comparative Effectiveness of a Web-Based Patient Decision Aid for Therapeutic Options for Sickle Cell Disease: Randomized Controlled Trial. Journal Of Medical Internet Research 2019, 21: e14462. PMID: 31799940, PMCID: PMC6934048, DOI: 10.2196/14462.
- Khemani K, Katoch D, Krishnamurti L. Curative Therapies for Sickle Cell Disease. Ochsner Journal 2019, 19: 131-137. PMID: 31258425, PMCID: PMC6584191, DOI: 10.31486/toj.18.0044.
- Sinha C, Bakshi N, Ross D, Krishnamurti L. Management of Chronic Pain in Adults Living With Sickle Cell Disease in the Era of the Opioid Epidemic. JAMA Network Open 2019, 2: e194410. PMID: 31125105, PMCID: PMC6632133, DOI: 10.1001/jamanetworkopen.2019.4410.
- Krishnamurti L, Neuberg D, Sullivan K, Kamani N, Abraham A, Campigotto F, Zhang W, Dahdoul T, De Castro L, Parikh S, Bakshi N, Haight A, Hassell K, Loving R, Rosenthal J, Smith S, Smith W, Spearman M, Stevenson K, Wu C, Wiedl C, Waller E, Walters M. Bone marrow transplantation for adolescents and young adults with sickle cell disease: Results of a prospective multicenter pilot study. American Journal Of Hematology 2019, 94: 446-454. PMID: 30637784, PMCID: PMC6542639, DOI: 10.1002/ajh.25401.
- Goel R, Chopra S, Tobian A, Ness P, Frank S, Cushing M, Vasovic L, Kaicker S, Takemoto C, Josephson C, Nellis M, Bussel J, Krishnamurti L. Platelet transfusion practices in immune thrombocytopenia related hospitalizations. Transfusion 2018, 59: 169-176. PMID: 30520045, DOI: 10.1111/trf.15069.
- Matthie N, Ross D, Sinha C, Khemani K, Bakshi N, Krishnamurti L. A Qualitative Study of Chronic Pain and Self-Management in Adults with Sickle Cell Disease. Journal Of The National Medical Association 2018, 111: 158-168. PMID: 30266214, PMCID: PMC6433553, DOI: 10.1016/j.jnma.2018.08.001.
- Phillips L, Krishnamurti L, Rytting H, Olson T. Ovarian Sertoli–Leydig tumor after bone marrow transplant for sickle cell disease. Pediatric Blood & Cancer 2018, 65: e27367. PMID: 30039911, DOI: 10.1002/pbc.27367.
- Sinha C, Bakshi N, Ross D, Krishnamurti L. From trust to skepticism: An in-depth analysis across age groups of adults with sickle cell disease on their perspectives regarding hydroxyurea. PLOS ONE 2018, 13: e0199375. PMID: 29949647, PMCID: PMC6021071, DOI: 10.1371/journal.pone.0199375.
- Bakshi N, Lukombo I, Belfer I, Krishnamurti L. Pain catastrophizing is associated with poorer health-related quality of life in pediatric patients with sickle cell disease. Journal Of Pain Research 2018, 11: 947-953. PMID: 29773954, PMCID: PMC5947835, DOI: 10.2147/jpr.s151198.
- Kato G, Piel F, Reid C, Gaston M, Ohene-Frempong K, Krishnamurti L, Smith W, Panepinto J, Weatherall D, Costa F, Vichinsky E. Sickle cell disease. Nature Reviews Disease Primers 2018, 4: 18010. PMID: 29542687, DOI: 10.1038/nrdp.2018.10.
- Zhang Y, Belfer I, Nouraie M, Zeng Q, Goel R, Chu Y, Krasiy I, Krishnamurti L. Association of genetic variation in COMT gene with pain related to sickle cell disease in patients from the walk-PHaSST study. Journal Of Pain Research 2018, 11: 537-543. PMID: 29559808, PMCID: PMC5856032, DOI: 10.2147/jpr.s149958.
- Bakshi N, Ross D, Krishnamurti L. Presence of pain on three or more days of the week is associated with worse patient reported outcomes in adults with sickle cell disease. Journal Of Pain Research 2018, 11: 313-318. PMID: 29445298, PMCID: PMC5810514, DOI: 10.2147/jpr.s150065.
- Bakshi N, Lukombo I, Belfer I, Krishnamurti L. Quantitative sensory testing is feasible and is well-tolerated in patients with sickle cell disease following a vaso-occlusive episode. Journal Of Pain Research 2018, 11: 435-443. PMID: 29503580, PMCID: PMC5827673, DOI: 10.2147/jpr.s150066.
- Jain S, Bakshi N, Krishnamurti L. Acute Chest Syndrome in Children with Sickle Cell Disease. Pediatric Allergy Immunology And Pulmonology 2017, 30: 191-201. PMID: 29279787, PMCID: PMC5733742, DOI: 10.1089/ped.2017.0814.
- Bakshi N, Sinha C, Ross D, Khemani K, Loewenstein G, Krishnamurti L. Proponent or collaborative: Physician perspectives and approaches to disease modifying therapies in sickle cell disease. PLOS ONE 2017, 12: e0178413. PMID: 28727801, PMCID: PMC5518995, DOI: 10.1371/journal.pone.0178413.
- Panepinto J, Paul Scott J, Badaki-Makun O, Darbari D, Chumpitazi C, Airewele G, Ellison A, Smith-Whitley K, Mahajan P, Sarnaik S, Charles Casper T, Cook L, Leonard J, Hulbert M, Powell E, Liem R, Hickey R, Krishnamurti L, Hillery C, Brousseau D, for the Pediatric Emergency Care Applied Research Network (PECARN). Determining the longitudinal validity and meaningful differences in HRQL of the PedsQL™ Sickle Cell Disease Module. Health And Quality Of Life Outcomes 2017, 15: 124. PMID: 28606098, PMCID: PMC5468970, DOI: 10.1186/s12955-017-0700-2.
- Bakshi N, Lukombo I, Shnol H, Belfer I, Krishnamurti L. Psychological Characteristics and Pain Frequency Are Associated With Experimental Pain Sensitivity in Pediatric Patients With Sickle Cell Disease. Journal Of Pain 2017, 18: 1216-1228. PMID: 28602692, DOI: 10.1016/j.jpain.2017.05.005.
- Bakshi N, Smith M, Ross D, Krishnamurti L. Novel Metrics in the Longitudinal Evaluation of Pain Data in Sickle Cell Disease. The Clinical Journal Of Pain 2017, 33: 517-527. PMID: 27584817, DOI: 10.1097/ajp.0000000000000431.
- Stenger E, Chinnadurai R, Yuan S, Garcia M, Arafat D, Gibson G, Krishnamurti L, Galipeau J. Bone Marrow–Derived Mesenchymal Stromal Cells from Patients with Sickle Cell Disease Display Intact Functionality. Transplantation And Cellular Therapy 2017, 23: 736-745. PMID: 28132869, PMCID: PMC5390328, DOI: 10.1016/j.bbmt.2017.01.081.
- Gluckman E, Cappelli B, Bernaudin F, Labopin M, Volt F, Carreras J, Pinto Simões B, Ferster A, Dupont S, de la Fuente J, Dalle J, Zecca M, Walters M, Krishnamurti L, Bhatia M, Leung K, Yanik G, Kurtzberg J, Dhedin N, Kuentz M, Michel G, Apperley J, Lutz P, Neven B, Bertrand Y, Vannier J, Ayas M, Cavazzana M, Matthes-Martin S, Rocha V, Elayoubi H, Kenzey C, Bader P, Locatelli F, Ruggeri A, Eapen M. Sickle cell disease: an international survey of results of HLA-identical sibling hematopoietic stem cell transplantation. Blood 2016, 129: 1548-1556. PMID: 27965196, PMCID: PMC5356458, DOI: 10.1182/blood-2016-10-745711.
- Shenoy S, Eapen M, Panepinto J, Logan B, Wu J, Abraham A, Brochstein J, Chaudhury S, Godder K, Haight A, Kasow K, Leung K, Andreansky M, Bhatia M, Dalal J, Haines H, Jaroscak J, Lazarus H, Levine J, Krishnamurti L, Margolis D, Megason G, Yu L, Pulsipher M, Gersten I, DiFronzo N, Horowitz M, Walters M, Kamani N. A trial of unrelated donor marrow transplantation for children with severe sickle cell disease. Blood 2016, 128: 2561-2567. PMID: 27625358, PMCID: PMC5123194, DOI: 10.1182/blood-2016-05-715870.
- Krishnamurti L. Iron-Deficiency Anemia. 2016, 2217-2227. DOI: 10.1542/9781610020473-part07-ch279.
- Jain D, Arjunan A, Sarathi V, Jain H, Bhandarwar A, Vuga M, Krishnamurti L. Clinical events in a large prospective cohort of children with sickle cell disease in Nagpur, India: evidence against a milder clinical phenotype in India. Pediatric Blood & Cancer 2016, 63: 1814-1821. PMID: 27279568, DOI: 10.1002/pbc.26085.
- Arnold S, Bhatia M, Horan J, Krishnamurti L. Haematopoietic stem cell transplantation for sickle cell disease – current practice and new approaches. British Journal Of Haematology 2016, 174: 515-525. PMID: 27255787, DOI: 10.1111/bjh.14167.
- Sayan M, Cassidy R, Butker E, Nanda R, Krishnamurti L, Khan M, Esiashvili N. Gonadal shielding technique to preserve fertility in male pediatric patients treated with total body irradiation for stem cell transplantation. Bone Marrow Transplantation 2016, 51: 997-998. PMID: 26950374, DOI: 10.1038/bmt.2016.25.
- Stenger E, Krishnamurti L, Galipeau J. Mesenchymal stromal cells to modulate immune reconstitution early post-hematopoietic cell transplantation. BMC Immunology 2015, 16: 74. PMID: 26674007, PMCID: PMC4681052, DOI: 10.1186/s12865-015-0135-7.
- Walters M, De Castro L, Sullivan K, Krishnamurti L, Kamani N, Bredeson C, Neuberg D, Hassell K, Farnia S, Campbell A, Petersdorf E. Indications and Results of HLA-Identical Sibling Hematopoietic Cell Transplantation for Sickle Cell Disease. Transplantation And Cellular Therapy 2015, 22: 207-211. PMID: 26500093, PMCID: PMC5031360, DOI: 10.1016/j.bbmt.2015.10.017.
- Creary S, Zickmund S, Ross D, Krishnamurti L, Bogen D. Hydroxyurea therapy for children with sickle cell disease: describing how caregivers make this decision. BMC Research Notes 2015, 8: 372. PMID: 26303306, PMCID: PMC4548690, DOI: 10.1186/s13104-015-1344-0.
- Brousseau D, Scott J, Badaki-Makun O, Darbari D, Chumpitazi C, Airewele G, Ellison A, Smith-Whitley K, Mahajan P, Sarnaik S, Casper T, Cook L, Dean J, Leonard J, Hulbert M, Powell E, Liem R, Hickey R, Krishnamurti L, Hillery C, Nimmer M, Panepinto J, Network F. A multicenter randomized controlled trial of intravenous magnesium for sickle cell pain crisis in children. Blood 2015, 126: 1651-1657. PMID: 26232172, PMCID: PMC4591790, DOI: 10.1182/blood-2015-05-647107.
- Ferrari R, Parker L, Grubs R, Krishnamurti L. Sickle Cell Trait Screening of Collegiate Athletes: Ethical Reasons for Program Reform. Journal Of Genetic Counseling 2015, 24: 873-877. PMID: 26040250, DOI: 10.1007/s10897-015-9849-1.
- Bakshi N, Stinson J, Ross D, Lukombo I, Mittal N, Joshi S, Belfer I, Krishnamurti L. Development, Content Validity, and User Review of a Web-based Multidimensional Pain Diary for Adolescent and Young Adults With Sickle Cell Disease. The Clinical Journal Of Pain 2015, 31: 580-590. PMID: 25565585, DOI: 10.1097/ajp.0000000000000195.
- Telen M, Wun T, McCavit T, De Castro L, Krishnamurti L, Lanzkron S, Hsu L, Smith W, Rhee S, Magnani J, Thackray H. Randomized phase 2 study of GMI-1070 in SCD: reduction in time to resolution of vaso-occlusive events and decreased opioid use. Blood 2015, 125: 2656-2664. PMID: 25733584, PMCID: PMC4408290, DOI: 10.1182/blood-2014-06-583351.
- Goel R, Ness P, Takemoto C, Krishnamurti L, King K, Tobian A. Platelet transfusions in platelet consumptive disorders are associated with arterial thrombosis and in-hospital mortality. Blood 2015, 125: 1470-1476. PMID: 25588677, PMCID: PMC4342358, DOI: 10.1182/blood-2014-10-605493.
- Italia Y, Krishnamurti L, Mehta V, Raicha B, Italia K, Mehta P, Ghosh K, Colah R. Feasibility of a Newborn Screening and Follow-up Programme for Sickle Cell Disease among South Gujarat (India) Tribal Populations. Journal Of Medical Screening 2014, 22: 1-7. PMID: 25341880, DOI: 10.1177/0969141314557372.
- Kato-Lin Y, Krishnamurti L, Padman R, Seltman H. Does e-pain plan improve management of sickle cell disease associated vaso-occlusive pain crisis? A mixed methods evaluation. International Journal Of Medical Informatics 2014, 83: 814-824. PMID: 25179666, DOI: 10.1016/j.ijmedinf.2014.08.003.
- Creary S, Krishnamurti L. Prodromal Illness Before Acute Chest Syndrome in Pediatric Patients With Sickle Cell Disease. Journal Of Pediatric Hematology/Oncology 2014, 36: 480-483. PMID: 24633302, DOI: 10.1097/mph.0000000000000146.
- Turaka K, Kietz D, Krishnamurti L, Mitchell E, Scanga H, Fu V, Sylvester C. Carcinoma-associated retinopathy in a young teenager with immature teratoma of the ovary. Journal Of American Association For Pediatric Ophthalmology And Strabismus 2014, 18: 396-398. PMID: 25173906, DOI: 10.1016/j.jaapos.2014.03.007.
- Shrikhande A, Arjunan A, Agarwal A, Dani A, Tijare J, Gettig E, Krishnamurti L. Prevalence of the βS Gene Among Scheduled Castes, Scheduled Tribes and Other Backward Class Groups in Central India. Hemoglobin 2014, 38: 230-235. PMID: 25023085, DOI: 10.3109/03630269.2014.931287.
- Gladwin M, Barst R, Gibbs J, Hildesheim M, Sachdev V, Nouraie M, Hassell K, Little J, Schraufnagel D, Krishnamurti L, Novelli E, Girgis R, Morris C, Rosenzweig E, Badesch D, Lanzkron S, Castro O, Taylor J, Goldsmith J, Kato G, Gordeuk V, Machado R, Investigators and Patients O. Risk Factors for Death in 632 Patients with Sickle Cell Disease in the United States and United Kingdom. PLOS ONE 2014, 9: e99489. PMID: 24988120, PMCID: PMC4079316, DOI: 10.1371/journal.pone.0099489.
- Klings E, Machado R, Morris C, Gordeuk V, Kato G, Ataga K, Castro O, Hsu L, Telen M, Krishnamurti L, Steinberg M, Gladwin M. Reply: Practice Guideline for Pulmonary Hypertension in Sickle Cell: Direct Evidence Needed before Universal Adoption. American Journal Of Respiratory And Critical Care Medicine 2014, 190: 238-240. PMID: 25025360, PMCID: PMC4226058, DOI: 10.1164/rccm.201404-0733le.
- Krishnamurti L, Smith‐Packard B, Gupta A, Campbell M, Gunawardena S, Saladino R. Impact of individualized pain plan on the emergency management of children with sickle cell disease. Pediatric Blood & Cancer 2014, 61: 1747-1753. PMID: 24962217, DOI: 10.1002/pbc.25024.
- Helton KJ, Investigators F, Adams R, Kesler K, Lockhart A, Aygun B, Driscoll C, Heeney M, Jackson S, Krishnamurti L, Miller S, Sarnaik S, Schultz W, Ware R. Magnetic resonance imaging/angiography and transcranial Doppler velocities in sickle cell anemia: results from the SWiTCH trial. Blood 2014, 124: 891-898. PMID: 24914136, PMCID: PMC4126329, DOI: 10.1182/blood-2013-12-545186.
- Bai Y, Krishnamurti L, Jia W, Mao Z, Sun M. An Electronic Six-Minute Walk Test Platform for Clinical Applications. 2014, 1-2. DOI: 10.1109/nebec.2014.6972715.
- Klings E, Machado R, Barst R, Morris C, Mubarak K, Gordeuk V, Kato G, Ataga K, Gibbs J, Castro O, Rosenzweig E, Sood N, Hsu L, Wilson K, Telen M, Decastro L, Krishnamurti L, Steinberg M, Badesch D, Gladwin M. An Official American Thoracic Society Clinical Practice Guideline: Diagnosis, Risk Stratification, and Management of Pulmonary Hypertension of Sickle Cell Disease. American Journal Of Respiratory And Critical Care Medicine 2014, 189: 727-740. PMID: 24628312, PMCID: PMC3983842, DOI: 10.1164/rccm.201401-0065st.
- Creary S, Gladwin M, Byrne M, Hildesheim M, Krishnamurti L. A pilot study of electronic directly observed therapy to improve hydroxyurea adherence in pediatric patients with sickle‐cell disease. Pediatric Blood & Cancer 2014, 61: 1068-1073. PMID: 24436121, DOI: 10.1002/pbc.24931.
- Nimgaonkar V, Krishnamurti L, Prabhakar H, Menon N. Comprehensive integrated care for patients with sickle cell disease in a remote aboriginal tribal population in southern India. Pediatric Blood & Cancer 2013, 61: 702-705. PMID: 24347362, DOI: 10.1002/pbc.24723.
- George M, Novelli E, Shigemura N, Simon M, Feingold B, Krishnamurti L, Morrell M, Gries C, Haider S, Johnson B, Crespo M, Bhama J, Bermudez C, Yousem S, Toyoda Y, Champion H, Pilewski J, Gladwin M. First Successful Lung Transplantation for Sickle Cell Disease with Severe Pulmonary Arterial Hypertension and Pulmonary Veno‐Occlusive Disease. Pulmonary Circulation 2013, 3: 952-958. PMID: 25006411, PMCID: PMC4070828, DOI: 10.1086/674749.
- Berg A, Courtney R, Krishnamurti L, Triulzi D, Yazer M. Is intensive monitoring during the first transfusion in pediatric patients necessary? Hematology 2013, 19: 304-308. PMID: 24074624, DOI: 10.1179/1607845413y.0000000122.
- Wun T, Soulieres D, Frelinger A, Krishnamurti L, Novelli E, Kutlar A, Ataga K, Knupp C, McMahon L, Strouse J, Zhou C, Heath L, Nwachuku C, Jakubowski J, Riesmeyer J, Winters K. A double-blind, randomized, multicenter phase 2 study of prasugrel versus placebo in adult patients with sickle cell disease. Journal Of Hematology & Oncology 2013, 6: 17. PMID: 23414938, PMCID: PMC3585853, DOI: 10.1186/1756-8722-6-17.
- Cruz R, Ranganathan S, Mazariegos G, Soltys K, Nayyar N, Sun Q, Bond G, Shaw P, Haberman K, Krishnamurti L, Marsh J, Humar A, Sindhi R. Analysis of national and single-center incidence and survival after liver transplantation for hepatoblastoma: New trends and future opportunities. Surgery 2013, 153: 150-159. PMID: 23331862, DOI: 10.1016/j.surg.2012.11.006.
- Nouraie M, Lee J, Zhang Y, Kanias T, Zhao X, Xiong Z, Oriss T, Zeng Q, Kato G, Gibbs J, Hildesheim M, Sachdev V, Barst R, Machado R, Hassell K, Little J, Schraufnagel D, Krishnamurti L, Novelli E, Girgis R, Morris C, Rosenzweig E, Badesch D, Lanzkron S, Castro O, Goldsmith J, Gordeuk V, Gladwin M. The relationship between the severity of hemolysis, clinical manifestations and risk of death in 415 patients with sickle cell anemia in the US and Europe. Haematologica 2012, 98: 464-472. PMID: 22983573, PMCID: PMC3659937, DOI: 10.3324/haematol.2012.068965.
- GOEL R, KRISHNAMURTI L. Mortality, health care utilization and associated diagnoses in hospitalized patients with haemophilia in the United States: first reported nationwide estimates. Haemophilia 2012, 18: 688-692. PMID: 22500777, DOI: 10.1111/j.1365-2516.2012.02774.x.
- Gheorghe G, Galambos C, Jain S, Krishnamurti L, Jaffe R. A Novel TCIRG1 Gene Mutation Leads to Severe Osteopetrosis with Altered Content of Monocytes/Macrophages in Several Organs. Pediatric And Developmental Pathology 2012, 15: 156-159. PMID: 22280207, DOI: 10.2350/11-05-1032-cr.1.
- Dovey S, Krishnamurti L, Sanfilippo J, Gunawardena S, Mclendon P, Campbell M, Alway S, Efymow B, Gracia C. Oocyte cryopreservation in a patient with sickle cell disease prior to hematopoietic stem cell transplantation: first report. Journal Of Assisted Reproduction And Genetics 2012, 29: 265-269. PMID: 22219083, PMCID: PMC3288130, DOI: 10.1007/s10815-011-9698-2.
- Wetzler M, Brown P, Hunger S, Sheppard C, Hillyer C, Guinan E, Rodriguez N, Jamieson K, Morales-Arias J, Pietrangelo A, Chitlur M, Kulkarni R, Carpenter S, Mazloom A, Paulman P, Kyle R, Rajkumar S, Shammo J, Bonilla M, Evens A, Cornett P, Andrès E, Sood S, Abrams C, Duggan P, Pierach C, Novelli E, Gladwin M, Krishnamurti L, Holstein S, Hohl R, Millward P, Brecher M, Kiss J. 13 Hematology. 2012, 767-871. DOI: 10.1016/b978-1-4557-0738-6.00013-9.
- Peters-Lawrence M, Bell M, Hsu L, Osunkwo I, Seaman P, Blackwood M, Guillaume E, Bellevue R, Krishnamurti L, Smith W, Dampier C, Minniti C, Network F. Clinical trial implementation and recruitment: Lessons learned from the early closure of a randomized clinical trial. Contemporary Clinical Trials 2011, 33: 291-297. PMID: 22155024, PMCID: PMC3577351, DOI: 10.1016/j.cct.2011.11.018.
- Sachdev V, Kato G, Gibbs J, Barst R, Machado R, Nouraie M, Hassell K, Little J, Schraufnagel D, Krishnamurti L, Novelli E, Girgis R, Morris C, Rosenzweig E, Badesch D, Lanzkron S, Castro O, Taylor J, Hannoush H, Goldsmith J, Gladwin M, Gordeuk V. Echocardiographic Markers of Elevated Pulmonary Pressure and Left Ventricular Diastolic Dysfunction Are Associated With Exercise Intolerance in Adults and Adolescents With Homozygous Sickle Cell Anemia in the United States and United Kingdom. Circulation 2011, 124: 1452-1460. PMID: 21900080, PMCID: PMC3183314, DOI: 10.1161/circulationaha.111.032920.
- Long K, Thomas S, Grubs R, Gettig E, Krishnamurti L. Attitudes and Beliefs of African‐Americans Toward Genetics, Genetic Testing, and Sickle Cell Disease Education and Awareness. Journal Of Genetic Counseling 2011, 20: 572-592. PMID: 21748660, DOI: 10.1007/s10897-011-9388-3.
- Kladny B, Williams A, Gupta A, Gettig E, Krishnamurti L. Genetic counseling following the detection of hemoglobinopathy trait on the newborn screen is well received, improves knowledge, and relieves anxiety. Genetics In Medicine 2011, 13: 658-661. PMID: 21546841, DOI: 10.1097/gim.0b013e31821435f7.
- Machado R, Barst R, Yovetich N, Hassell K, Kato G, Gordeuk V, Gibbs J, Little J, Schraufnagel D, Krishnamurti L, Girgis R, Morris C, Rosenzweig E, Badesch D, Lanzkron S, Onyekwere O, Castro O, Sachdev V, Waclawiw M, Woolson R, Goldsmith J, Gladwin M, Investigators and Patients O. Hospitalization for pain in patients with sickle cell disease treated with sildenafil for elevated TRV and low exercise capacity. Blood 2011, 118: 855-864. PMID: 21527519, PMCID: PMC3148167, DOI: 10.1182/blood-2010-09-306167.
- Aloe A, Krishnamurti L, Kladny B. Testing of Collegiate Athletes for Sickle Cell Trait: What We, as Genetic Counselors Should Know. Journal Of Genetic Counseling 2011, 20: 337-340. PMID: 21503822, DOI: 10.1007/s10897-011-9366-9.
- Gladwin M, Kato G, Weiner D, Onyekwere O, Dampier C, Hsu L, Hagar R, Howard T, Nuss R, Okam M, Tremonti C, Berman B, Villella A, Krishnamurti L, Lanzkron S, Castro O, Gordeuk V, Coles W, Peters-Lawrence M, Nichols J, Hall M, Hildesheim M, Blackwelder W, Baldassarre J, Casella J, Investigators F. Nitric Oxide for Inhalation in the Acute Treatment of Sickle Cell Pain Crisis: A Randomized Controlled Trial. JAMA: The Journal Of The American Medical Association 2011, 305: 893-902. PMID: 21364138, PMCID: PMC3403835, DOI: 10.1001/jama.2011.235.
- Hematopoietic Stem Cell Transplantation for Hemoglobinopathies: Current Practice and Emerging TrendsSmiers F, Krishnamurti L, Lucarelli G. Hematopoietic Stem Cell Transplantation for Hemoglobinopathies: Current Practice and Emerging Trends. Pediatric Clinics Of North America 2010, 57: 181-205. PMID: 20307718, DOI: 10.1016/j.pcl.2010.01.003.
- Buchanan G, Vichinsky E, Krishnamurti L, Shenoy S. Severe Sickle Cell Disease—Pathophysiology and Therapy. Transplantation And Cellular Therapy 2009, 16: s64-s67. PMID: 19819341, PMCID: PMC2832723, DOI: 10.1016/j.bbmt.2009.10.001.
- Rao V, Price S, Perkins K, Aldridge P, Tretler J, Davis J, Dale J, Gill F, Hartman K, Stork L, Gnarra D, Krishnamurti L, Newburger P, Puck J, Fleisher T. Use of rituximab for refractory cytopenias associated with autoimmune lymphoproliferative syndrome (ALPS). Pediatric Blood & Cancer 2009, 52: 847-852. PMID: 19214977, PMCID: PMC2774763, DOI: 10.1002/pbc.21965.
- Krishnamurti L, Kharbanda S, Biernacki M, Zhang W, Baker K, Wagner J, Wu C. Stable Long-Term Donor Engraftment following Reduced-Intensity Hematopoietic Cell Transplantation for Sickle Cell Disease. Transplantation And Cellular Therapy 2008, 14: 1270-1278. PMID: 18940682, DOI: 10.1016/j.bbmt.2008.08.016.
- Krishnamurti L. Iron-Deficiency Anemia. 2008, 2201-2211. DOI: 10.1542/9781581106411-9-ch287.
- Krishnamurti L, Bunn H, Williams A, Tolar J. Hematopoietic Cell Transplantation for Hemoglobinopathies. Current Problems In Pediatric And Adolescent Health Care 2008, 38: 6-18. PMID: 18068866, DOI: 10.1016/j.cppeds.2007.10.002.
- Krishnamurti L, Gupta D. Hematopoietic stem cell transplantation for hemoglobinopathies: Progress and prospects. Indian Journal Of Medical And Paediatric Oncology 2008, 29: 39-48. DOI: 10.4103/0971-5851.51444.
- Adamkiewicz T, Szabolcs P, Haight A, Baker K, Staba S, Kedar A, Chiang K, Krishnamurti L, Boyer M, Kurtzberg J, Wagner J, Wingard J, Yeager A. Unrelated cord blood transplantation in children with sickle cell disease: Review of four‐center experience. Pediatric Transplantation 2007, 11: 641-644. PMID: 17663687, DOI: 10.1111/j.1399-3046.2007.00725.x.
- Gustafson S, Gettig E, Watt-Morse M, Krishnamurti L. Health beliefs among African American women regarding genetic testing and counseling for sickle cell disease. Genetics In Medicine 2007, 9: 303-310. PMID: 17505208, DOI: 10.1097/gim.0b013e3180534282.
- Krishnamurti L. Hematopoietic cell transplantation for sickle cell disease: state of the art. Expert Opinion On Biological Therapy 2007, 7: 161-172. PMID: 17250455, DOI: 10.1517/14712598.7.2.161.
- Krishnamurti L. HEMATOPOIETIC CELL TRANSPLANTATION: A Curative Option for Sickle Cell Disease. Pediatric Hematology And Oncology 2007, 24: 569-575. PMID: 18092247, DOI: 10.1080/08880010701640531.
- LaRosa C, McMullen L, Bakdash S, Ellis D, Krishnamurti L, Wu H, Moritz M. Acute renal failure from xanthine nephropathy during management of acute leukemia. Pediatric Nephrology 2006, 22: 132-135. PMID: 17039332, DOI: 10.1007/s00467-006-0287-z.
- Patik M, Phillips L, Kladny B, Captain A, Gettig E, Krishnamurti L. Structured telephone‐based outreach using nonmedical personnel can improve adherence to comprehensive care in families of children with sickle cell disease. American Journal Of Hematology 2006, 81: 462-464. PMID: 16680738, DOI: 10.1002/ajh.20605.
- Krishnamurti L, Lanford L, Munoz R. Life threatening parvovirus B19 and herpes simplex virus associated acute myocardial dysfunction in a child with homozygous sickle cell disease. Pediatric Blood & Cancer 2006, 49: 1019-1021. PMID: 16700044, DOI: 10.1002/pbc.20855.
- Ambrusko S, Gunawardena S, Sakara A, Windsor B, Lanford L, Michelson P, Krishnamurti L. Elevation of tricuspid regurgitant jet velocity, a marker for pulmonary hypertension in children with sickle cell disease. Pediatric Blood & Cancer 2006, 47: 907-913. PMID: 16496290, DOI: 10.1002/pbc.20791.
- Krishnamurti L. Commentary on “Identification of Unrelated Cord Blood Units for Hematopoietic Stem Cell Transplantation in Children With Sickle Cell Disease”. Journal Of Pediatric Hematology/Oncology 2006, 28: 1-3. PMID: 16394884, DOI: 10.1097/01.mph.0000196448.99446.0a.
- Kladny B, Gettig E, Krishnamurti L. Systematic follow-up and case management of the abnormal newborn screen can improve acceptance of genetic counseling for sickle cell or other hemoglobinopathy trait. Genetics In Medicine 2005, 7: 139-142. PMID: 15714082, DOI: 10.1097/01.gim.0000153662.88425.68.
- Wilson R, Krishnamurti L, Kamat D. Management of Sickle Cell Disease in Primary Care. Clinical Pediatrics 2003, 42: 753-761. PMID: 14686547, DOI: 10.1177/000992280304200901.
- Krishnamurti L, Abel S, Maiers M, Flesch S. Availability of unrelated donors for hematopoietic stem cell transplantation for hemoglobinopathies. Bone Marrow Transplantation 2003, 31: 547-550. PMID: 12692619, DOI: 10.1038/sj.bmt.1703887.
- Pastore Y, Jelinek J, Ang S, Guan Y, Liu E, Jedlickova K, Krishnamurti L, Prchal J. Mutations in the VHL gene in sporadic apparently congenital polycythemia. Blood 2002, 101: 1591-1595. PMID: 12393546, DOI: 10.1182/blood-2002-06-1843.
- Zapzalka D, Krishnamurti L, Manivel J, DiSandro M. Lymphangioma of the Renal Capsule. Journal Of Urology 2002, 168: 220. PMID: 12050546, DOI: 10.1016/s0022-5347(05)64895-1.
- Krishnamurti L, Neglia J, Nagarajan R, Berry S, Lohr J, Hirsch B, White J. Paris‐Trousseau syndrome platelets in a child with Jacobsen's syndrome. American Journal Of Hematology 2001, 66: 295-299. PMID: 11279643, DOI: 10.1002/ajh.1061.
- Krishnamurti L, Blazar B, Wagner J. Bone Marrow Transplantation without Myeloablation for Sickle Cell Disease. The New England Journal Of Medicine 2001, 344: 68. PMID: 11187121, DOI: 10.1056/nejm200101043440119.
- Krishnamurti L. Few Reports of Hemoglobin E/β-Thalassemia in Northeast India: Underdiagnosis or Complete Exclusion of β-Thalassemia by Hemoglobin E. Journal Of Pediatric Hematology/Oncology 2000, 22: 558-563. PMID: 11132230, DOI: 10.1097/00043426-200011000-00023.
- Krishnamurti L, Neglia J, Nagarajan R, Berry S, Hirsch B, Matsunaga A, White J. Paris-Trousseau platelets: a manifestation of Jacobsen syndrome. Journal Of Pediatric Hematology/Oncology 2000, 22: 373. DOI: 10.1097/00043426-200007000-00046.
- Recurrence of EBV associated, high-grade, post-transplant lymphoma presenting as acute renal failureLewis V, Dahl J, Braunlin E, Steiner M, Perentesis J, Neglia J, Krishnamurti L. Recurrence of EBV associated, high-grade, post-transplant lymphoma presenting as acute renal failure. Journal Of Pediatric Hematology/Oncology 2000, 22: 378-379. DOI: 10.1097/00043426-200007000-00065.
- Krishnamurti L, Blazar B, Grossi M, Abel S, Vichinsky E, Lubin B, Wagner J. Treatment of sickle cell disease (SCD) by an allogeneic hematopoietic stem cell transplantation (HSCT) using a non-myeloablative preparative regimen. Journal Of Pediatric Hematology/Oncology 2000, 22: 387. DOI: 10.1097/00043426-200007000-00093.
- Weigel B, Lasky A, Krishnamurti L, Perentesis J, Neglia J, Foker J, Key N, Edson R, Steiner M. #432 Danaparoid (orgaran) anti-coagulation of pediatric patients with heparin-induced thrombocytopenia (HIT). Journal Of Pediatric Hematology/Oncology 1999, 21: 457. DOI: 10.1097/00043426-199909000-00035.
- Weigel B, Lasky A, Krishnamurti L, Perentesis J, Neglia J, Foker J, Key N, Edson R, Steiner M. #432 Danaparoid (orgaran) anticoagulation of pediatric patients with heparininduced thrombocytopenia (HIT). Journal Of Pediatric Hematology/Oncology 1999, 21: 327. DOI: 10.1097/00043426-199907000-00093.
- KRISHNAMURTI L, LITTLE J. Homozygous Hemoglobin Constant Spring with Normal Electrophoresis: A Possible Cause for Under‐Diagnosis. Annals Of The New York Academy Of Sciences 1998, 850: 415-419. PMID: 9668571, DOI: 10.1111/j.1749-6632.1998.tb10508.x.
- Krishnamurti L, Chui D, Dallaire M, LeRoy B, Waye J, Perentesis J. Coinheritance of α-thalassemia-1 and hemoglobin E/β0-thalassemia: Practical implications for neonatal screening and genetic counseling. The Journal Of Pediatrics 1998, 132: 863-865. PMID: 9602201, DOI: 10.1016/s0022-3476(98)70319-1.
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