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- Yale Sleep Medicine Centers1291 Boston Post RoadMadison, CT 06443
- Yale Sleep Medicine Centers8 Devine StreetNorth Haven, CT 06473
Henry Yaggi, MD, MPH
Sleep Medicine, Pulmonology & Sleep Medicine
Telehealth is available
Patient type treated
Adult
Accepting new patients
Yes
Referral required
From patients or physicians
Board Certified in
Critical Care Medicine (Internal Medicine) and Sleep Medicine
Biography
Henry Yaggi, MD, MPH, is director of the Sleep Medicine Program and a specialist in pulmonary, critical care, and sleep medicine.
Dr. Yaggi’s patient care and research focuses on the intersection between sleep medicine and other specialties, including cardiovascular health, metabolic health, and cognitive function.
He often treats patients with sleep apnea, a sleeping disorder in which breathing stops and starts frequently during the night. His research explores many aspects of sleep apnea, including why it raises risk for cardiovascular and metabolic health issues and how at-home diagnosis and treatment of sleep apnea impacts cardiovascular risk.
Dr. Yaggi’s goal is to emphasize to his patients how important sleep is for their overall health and well-being and to make treatment for sleep disorders more accessible. Some of his research looks at how cognitive behavioral therapy can help patients who have insomnia and heart failure.
He is also a principal investigator at the National VA Clinical Epidemiology Research Center.
Titles
- Professor of Internal Medicine (Pulmonary, Critical Care & Sleep Medicine)
- Vice Chief of Research, Pulmonary, Critical Care & Sleep Medicine
- Director, Yale Centers for Sleep Medicine, Pulmonary, Critical Care & Sleep Medicine
Education & Training
- FellowYale-New Haven Hospital (2003)
- MPHYale School of Public Health, Chronic Disease Epidemiology (2003)
- VA Clinical Scholar Research FellowYale University (2000)
- ResidentYale-New Haven Hospital (1999)
- MDUniversity of Maryland/Baltimore County (1996)
- BAJohns Hopkins University (1992)
Additional Information
Honors & Recognitions
- Mentee Andrey Zinchuk, 12th Annual Young Investigators Award: Respiratory Disease Forum (2019)
- Mentee Andrey Zinchuk selected as Young investigator of the Year: Associated Professional Sleep Society, National SLEEP Meeting (2018)
- "Cardiovascular Phenotypes and their Cardiovascular Implications" cited as a top 10 article of the year: Associated Professional Sleep Society, National SLEEP Meeting (2018)
- "Cardiovascular phenotypes and their cardiovascular implication in Obstructive Sleep Apnea" Highlighted paper: British Thoracic Society (2017)
- Faculty Achievement Award for Accomplishment in Research: Yale University School of Medicine, Department of Medicine (2010)
- Ralph Horowitz Annual Lecturer in Clinical Epidemiology: Yale University School of Medicine, Department of Medicine (2010)
- Advanced Career Development Award: VA Clinical Science Research and Development Service (2008)
- A Top 5 Cited Article in Sleep Medicine, “Obstructive Sleep Apnea as a Risk Factor for Stroke and Death” cited by American: American Thoracic Society (2006)
- “The Year in Medicine from A to Z” ; (cited our research related to obstructive sleep apnea and stroke). Highlighted on Today Show.: Time Magazine (2005)
- Master’s Thesis with Honors in Public Health: Yale University School of Epidemiology and Public Health (2003)
Board Certifications
- AB of Internal Medicine, Critical Care Medicine (Internal Medicine) (2006, recertified: 2020)
- AB of Sleep Medicine, Sleep Medicine (2004)
Professional Service
- NIH/NHLBI (U01) "New Epidemiology Cohort Studies in Heart, Lung, Blood and Sleep Disorders" (2019): Committee Member
- Sleep in Heavenly Peace (Construction of Beds for Children in New Haven) (2019 - Present): Participant
- New Haven Bed Race, Fundraiser for the Connecticut Burns Care Foundation (2018 - Present): Volunteer
- CHEST, Sleep Medicine Board Review Course, Pheonix, AZ (2017 - 2019): Chair
- Bayer Pharmaceuticals (2017): Committee Member
- Closer to Free Ride, Fundraiser for Smilow Cancer Center (2017 - Present): Participant
- ALA Autumn Trek, Fundraiser for the American Lung Association (2016 - Present): Participant
- Yale Center for Clinical Investigation (YCCI), Study Section for YCCI Clinical and Community Research Scholar Awards (2015 - 2017): Committee Member
- CHEST Sleep Medicine Board Review Course, Orlando, FL (2015 - 2017): Co-Chair
- Research Advisory Panel, Food and Drug Administration, Upper Airway Neurostimulation for the Treatment of Obstructive Sleep Apnea (2014): Member
Publications
- Knauert M, Adekolu O, Xu Z, Deng A, Chu J, Baldassarri S, Kushida C, Yaggi H, Zinchuk A. Morning Chronotype Is Associated with Improved Adherence to Continuous Positive Airway Pressure among Individuals with Obstructive Sleep Apnea. Annals Of The American Thoracic Society 2023, 20: 1182-1191. PMID: 36917194, PMCID: PMC10405611, DOI: 10.1513/annalsats.202210-885oc.
- Redeker N, Conley S, O'Connell M, Geer J, Yaggi H, Jeon S. Sleep-related predictors of cognition among adults with chronic insomnia and heart failure enrolled in a randomized controlled trial of cognitive behavioral therapy for insomnia. Journal Of Clinical Sleep Medicine 2023, 19: 1073-1081. PMID: 36740924, PMCID: PMC10235706, DOI: 10.5664/jcsm.10498.
- Aneni E, Saeed G, Thorn S, Miller E, Sinusas A, Yaggi H. 0488 The Relationship between Myocardial Blood Flow and Diastolic Function in a Clinical Population with Obstructive Sleep Apnea. Sleep 2023, 46: a217-a217. DOI: 10.1093/sleep/zsad077.0488.
- Miner B, Pan Y, Burzynski C, Iannone L, Knauert M, Gill T, Yaggi H. 0726 Agreement Between an Electroencephalography-Measuring Headband and Polysomnography in Older Adults with Sleep Disturbances. Sleep 2023, 46: a319-a320. DOI: 10.1093/sleep/zsad077.0726.
- Lukas M, Doyle M, Intihar T, Wright K, Redeker N, Pisani M, Yaggi H, Knauert M. 0841 Feasibility of Actigraphy during a Daytime Bright Pilot Study in the Medical ICU. Sleep 2023, 46: a370-a371. DOI: 10.1093/sleep/zsad077.0841.
- Intihar T, Doyle M, Lukas M, Wright K, Redeker N, Pisani M, Yaggi H, Knauert M. 0842 Feasibility of daytime bright light exposure and urinary 6-sulfatoxymelatonin profiling in the medical ICU: A pilot study. Sleep 2023, 46: a371-a371. DOI: 10.1093/sleep/zsad077.0842.
- Walker A, Baldassarri S, Chu J, Deng A, Xu Z, Blohowiak R, Byrne S, Kushida C, Yaggi H, Zinchuk A. 0480 Psychoactive Substance Use and Sleep Characteristics Among Individuals with Untreated Obstructive Sleep Apnea. Sleep 2023, 46: a213-a214. DOI: 10.1093/sleep/zsad077.0480.
- Jeon S, Conley S, Hollenbeak C, O’Connell M, Yaggi H, Jacoby D, Wang Z, Tocchi C, Redeker N. 0395 Effects of Insomnia and Rest-Activity on Hospitalizations and Emergency Department Visits in People with Stable Heart Failure. Sleep 2023, 46: a175-a175. DOI: 10.1093/sleep/zsad077.0395.
- Nwanaji-Enwerem U, Sadler L, Jeon S, Barry D, Yaggi H, Redeker N. 0144 A Mixed Methods Exploration of Stigma, Discrimination, and Sleep among Individuals on Medication for Opioid Use Disorder. Sleep 2023, 46: a65-a65. DOI: 10.1093/sleep/zsad077.0144.
- Cox R, Haller S, Martinez-Lisowska Z, Kuppa A, Sprecher K, Withrow D, Barry D, Scheinost D, Redeker N, Yaggi H, Wright K. 0677 Blunted daily light rhythm amplitude in adults with opioid use disorder (OUD). Sleep 2023, 46: a297-a298. DOI: 10.1093/sleep/zsad077.0677.
- Mehta S, Peterson H, Ibrahim A, Saeed G, Linsky S, Kreinin I, Tsang S, Nwanaji-Enwerem U, Raso A, Barry D, Redeker N, Yaggi H, Scheinost D. 350. Brain Volume Alterations in Individuals With Opioid Use Disorder. Biological Psychiatry 2023, 93: s235. DOI: 10.1016/j.biopsych.2023.02.590.
- Baldassarri S, Chu J, Deng A, Xu Z, Blohowiak R, Byrne S, Kushida C, Yaggi H, Zinchuk A. Nicotine, alcohol, and caffeine use among individuals with untreated obstructive sleep apnea. Sleep And Breathing 2023, 27: 2479-2490. PMID: 37058215, PMCID: PMC10576010, DOI: 10.1007/s11325-023-02830-3.
- Wojeck B, Inzucchi S, Qin L, Yaggi H. Polysomnographic predictors of incident diabetes and pre-diabetes: an analysis of the DREAM study. Journal Of Clinical Sleep Medicine 2023, 19: 703-710. PMID: 36689314, PMCID: PMC10071389, DOI: 10.5664/jcsm.10414.
- Aneni E, Thorn S, Feher A, Hong Chen J, Sinusas A, Yaggi H, Miller E. The Association Between Obstructive Sleep Apnea and Abnormal 82Rubidium Cardiac PET Perfusion Myocardial Flow Reserve. JACC Cardiovascular Imaging 2023, 16: 856-858. PMID: 36881426, PMCID: PMC10718199, DOI: 10.1016/j.jcmg.2022.11.024.
- Geer J, Karagoz E, Yaggi H. Sleep apnea and stroke. 2023, 271-277. DOI: 10.1016/b978-0-12-822963-7.00325-x.
- Miner B, Doyle M, Knauert M, Yaggi H, Stone K, Ancoli‐Israel S, Cauley J, Redline S, Blackwell T, Gill T, Groups F. Insomnia with objective short sleep duration in community‐living older persons: A multifactorial geriatric health condition. Journal Of The American Geriatrics Society 2022, 71: 1198-1208. PMID: 36524599, PMCID: PMC10089942, DOI: 10.1111/jgs.18195.
- Dreyer R, Berkowitz A, Yaggi H, Schneeberg L, Shah N, Emanuel L, Prakash K, Jeffery M, Thorndike F, Deeg M, Ervin K, Ross J. PreScription DigitaL ThErapEutic For Patients with Insomnia (SLEEP-I): A Protocol for a Pragmatic Randomized Controlled Trial. Sleep Medicine 2022, 100: s133-s134. DOI: 10.1016/j.sleep.2022.05.365.
- Aneni E, Chen J, Thorn S, Miller E, Sinusas A, Yaggi H. Obstructive Sleep Apnea Severity is Associated with Abnormal Myocardial 82Rubidium PET Blood Flow Reserve. Sleep Medicine 2022, 100: s261. DOI: 10.1016/j.sleep.2022.05.703.
- Wojeck B, Inzucchi S, Neeland I, Mancuso J, Frederich R, Masiukiewicz U, Cater N, McGuire D, Cannon C, Yaggi H. Ertugliflozin and Incident Obstructive Sleep Apnea: An Analysis from the VERTIS CV Trial. Sleep Medicine 2022, 100: s249-s250. DOI: 10.1016/j.sleep.2022.05.671.
- Saeed G, Aneni E, Otite F, Thorn S, Miller E, Sinusas A, Yaggi H. Abstract 14839: Clinical, Polysomnographic and Echocardiographic Correlates of Excessive Daytime Sleepiness. Circulation 2022, 146: a14839-a14839. DOI: 10.1161/circ.146.suppl_1.14839.
- Aneni E, Miller E, Saeed G, deKemp R, KLEIN R, Beanlands R, Yaggi H, Sinusas A, Thorn S. Abstract 13798: Obstructive Sleep Apnea Severity and Abnormal Right Ventricular Flow Reserve in Adult OSA Patients Who Received Rubidium-82 Cardiac PET Perfusion Imaging. Circulation 2022, 146: a13798-a13798. DOI: 10.1161/circ.146.suppl_1.13798.
- Hollenbeak C, Jeong S, O'Connell M, Redeker N, Yaggi H. Abstract 10200: Costs and Resource Utilization of People With Stable Heart Failure and Insomnia: Evidence From a Randomized Trial. Circulation 2022, 146: a10200-a10200. DOI: 10.1161/circ.146.suppl_1.10200.
- Sharma A, Byrne S, Deng A, Chu J, Sands S, Wellman A, Redeke N, Yaggi H, Zinchuk A. 0158 Risk perception, outcome expectancy, and treatment self-efficacy among women and men with obstructive sleep apnea (OSA). Sleep 2022, 45: a73-a73. DOI: 10.1093/sleep/zsac079.156.
- Byrne S, Sharma A, Deng A, Chu J, Sands S, Wellman A, Redeker N, Yaggi H, Zinchuk A. 0790 Racial Differences in Self-Efficacy for Positive Airway Pressure Therapy Among Individuals Newly Diagnosed with Obstructive Sleep Apnea. Sleep 2022, 45: a343-a343. DOI: 10.1093/sleep/zsac079.786.
- Miner B, Yaggi H, Gill T, Doyle M, Stone K, Redline S, Ensrud K, Blackwell T, Knauert M. 0321 Poor Agreement Among Self-Reported and Objective Sleep Deficiency Assessments in Older Persons. Sleep 2022, 45: a144-a145. DOI: 10.1093/sleep/zsac079.319.
- Miner B, Stone KL, Zeitzer JM, Han L, Doyle M, Blackwell T, Gill TM, Redeker NS, Hajduk A, Yaggi H. Self-reported and actigraphic short sleep duration in older adults. Journal Of Clinical Sleep Medicine 2022, 18: 403-413. PMID: 34338629, PMCID: PMC8804982, DOI: 10.5664/jcsm.9584.
- Ding Q, Qin L, Wojeck B, Inzucchi SE, Ibrahim A, Bravata DM, Strohl KP, Yaggi HK, Zinchuk AV. Polysomnographic Phenotypes of Obstructive Sleep Apnea and Incident Type 2 Diabetes: Results from the DREAM Study. Annals Of The American Thoracic Society 2021, 18: 2067-2078. PMID: 34185617, PMCID: PMC8641817, DOI: 10.1513/annalsats.202012-1556oc.
- Ding Q, Qin L, Wojeck B, Inzucchi S, Ibrahim A, Bravata D, Strohl K, Yaggi H, Zinchuk A. Associations Between Polysomnographic Phenotypes of Obstructive Sleep Apnea and Incident Type 2 Diabetes. 2021, a4679-a4679. DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a4679.
- Adekolu O, Xu Z, Chu J, Kushida C, Yaggi H, Knauert M, Zinchuk A. 441 Influence Of Chronotype On CPAP Adherence. Sleep 2021, 44: a174-a175. DOI: 10.1093/sleep/zsab072.440.
- Kunitomo Y, Lee M, DeRycke E, Yaggi H, Bastian L. Prevalence of Obstructive Sleep Apnea in a Cohort of Veterans with Chronic Pain and Active Smoking History. 2021, a1564-a1564. DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1564.
- Redeker N, Bessette A, Breazeale S, Conley S, Hollenbeak C, Hwang Y, Iannacco J, Jacoby D, Kelly-Hauser J, Linsky S, Moemeka L, Nwanaji-Enwerem U, O’Connell M, Yaggi H, Jeon S. 342 CBT-I Has Sustained Effects on Insomnia Versus Heart-Failure Self-Management Education among Adults with Chronic Heart Failure. Sleep 2021, 44: a136-a137. DOI: 10.1093/sleep/zsab072.341.
- Zinchuk A, Yaggi H. Treatment-Emergent Central Sleep Apnea. 2021, 85-102. DOI: 10.1007/978-3-030-57942-5_8.
- Anker S, Fitchett D, Zinman B, Ofstad A, Wanner C, Vedin O, Schinzel B, Yaggi H, George J, Sander L, Inzucchi S, Verma S. Abstract 14962: Empagliflozin’s Cardiovascular Impact in High-Risk Patients With Type 2 Diabetes and Obstructive Pulmonary Disease: An Inquiry From EMPA-REG OUTCOME. Circulation 2020, 142 DOI: 10.1161/circ.142.suppl_3.14962.
- Yaggi H, Eliasson B, Kasai T, Marx N, Zinman B, Inzucchi S, Wanner C, Zwiener I, Wojeck B, Neeland I, Johansen O. Obstructive sleep apnoe and cardiovascular, heart failure and mortality outcomes with empagliflozin versus placebo in the EMPA-REG OUTCOME trial. European Heart Journal 2020, 41 DOI: 10.1093/ehjci/ehaa946.2883.
- NEELAND I, ELIASSON B, KASAI T, MARX N, ZINMAN B, INZUCCHI S, WANNER C, ZWIENER I, WOJECK B, YAGGI H, JOHANSEN O. 1128-P: Empagliflozin and Obstructive Sleep Apnea (OSA): Exploratory Analysis from the EMPA-REG OUTCOME Trial. Diabetes 2020, 69 DOI: 10.2337/db20-1128-p.
- Miner B, Fragoso C, Han L, Yaggi H, Redeker N, Stone K. 0852 Geriatric Health Conditions And The Combined Outcome Of Poor Sleep Quality With Objective Short Sleep Duration. Sleep 2020, 43: a324-a325. DOI: 10.1093/sleep/zsaa056.848.
- Miner B, Fragoso C, Han L, Stone K, Redeker N, Yaggi H. 0855 Primary Sleep Disorders And The Combined Outcome Of Poor Sleep Quality With Objective Short Sleep Duration In Older Persons. Sleep 2020, 43: a325-a326. DOI: 10.1093/sleep/zsaa056.851.
- Zinchuk A, Yaggi H, Liang J, Chu J, De Beeck S, Stepnowski C, Wellman A, Peker Y, Sands S. 0568 Physiologic OSA Traits and CPAP Adherence Among Patients with Coronary Artery Disease and OSA. Sleep 2020, 43: a218-a218. DOI: 10.1093/sleep/zsaa056.565.
- Liu J, Yaggi H. Maximal Airflow Increase Rate (MAFIR): A New Metric of Arousal Threshold and a Cause of Respiratory Arousal. 2020, a6455-a6455. DOI: 10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a6455.
- Geer J, Vanent K, Leasure A, Pisani M, Sansing L, Woo D, Langefeld C, Falcone G, Sheth K, Yaggi H. Obstructive Sleep Apnea: A Prevalent and Novel Risk Factor for Intracerebral Hemorrhage. 2020, a2713-a2713. DOI: 10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a2713.
- Yaggi H, Eliasson B, Kasai T, Marx N, Zinman B, Inzucchi S, Wanner C, Zwiener I, Wojeck B, Neeland I, Johansen O. Obstructive Sleep Apnoe and Cardiovascular, Heart Failure and Mortality Outcomes with Empagliflozin Versus Placebo in the EMPA-REG Outcome ® Trial. 2020, a4713-a4713. DOI: 10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a4713.
- Zinchuk A, Yaggi H, Liang J, Chu J, Op de Beeck S, Stepnowsky C, Wellman D, Peker Y, Sands S. Physiologic Traits Predict Therapeutic Pressure Requirements and Residual Respiratory Events Among Patients with Coronary Artery Disease and Obstructive Sleep Apnea. 2020, a6439-a6439. DOI: 10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a6439.
- Geer J, Leasure A, Vanent K, Sansing L, Woo D, Langefeld C, Yaggi H, Falcone G, Sheth K. Abstract TP347: Obstructive Sleep Apnea Frequency in Intracerebral Hemorrhage. Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.tp347.
- Zinchuk A, Yaggi H, Concato J, Jeon S, Bravata D, Wellman D, Sands S. Low Arousal Threshold Correlates with Reduced Continuous Positive Airway Pressure Use in Non-Obese Individuals with Obstructive Sleep Apnea and Stroke. 2019, a2598-a2598. DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2598.
- Zinchuk A, Yaggi H, Concato J, Wellman D, Smales E, Hess L, Denos J, Peker Y, Sands S. Effect of Arousal Scoring on Reliability of Automated, Non-Invasive Phenotyping of Physiologic Sleep Apnea Traits from Polysomnography. 2019, a7078-a7078. DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7078.
- Liu J, Qin L, Yaggi H. 0138 Physiological Effects of Respiratory Events that Terminate Without Arousals During Sleep. Sleep 2019, 42: a56-a57. DOI: 10.1093/sleep/zsz067.137.
- Liu J, Qin L, McConaughey C, Yaggi H. 0494 Associations of Obstructive Sleep Apnea with Renal Function Decline in a Cohort of Veterans. Sleep 2019, 42: a198-a198. DOI: 10.1093/sleep/zsz067.492.
- Miner B, MHS M, Stone K, Hajduk A, Yaggi H, Redeker N, Fragoso C. 0709 Self-Reported and Actigraphic Short Sleep Duration in Older Persons. Sleep 2019, 42: a284-a285. DOI: 10.1093/sleep/zsz067.707.
- Liu J, Yaggi H. Characterization of Arousals in Polysomnography Using the Statistical Significance of Power Change. 2018, 00: 1-6. DOI: 10.1109/spmb.2018.8615603.
- Zinchuk A, Jeon S, Yaggi H. 0466 High Frequency Of PLMS Is Associated With Increased Risk Of Incident Adverse Cardiovascular Events And Death Among OSA Patients. Sleep 2018, 41: a176-a176. DOI: 10.1093/sleep/zsy061.465.
- Williams C, Yaggi H, Kuna S, Asare V. 0943 Dream Enactment Behavior in Post Traumatic Stress Disorder Patients. Sleep 2018, 41: a350-a350. DOI: 10.1093/sleep/zsy061.942.
- Conley S, Jeon S, Yaggi H, Jacoby D, Hollenbeak C, O’Connell M, Linsky S, Darden J, Gaiser E, Kelly-Hauser J, Matthew B, Richardson P, Redeker N. 0881 Insomnia Is Related To Self-care In People With Stable Heart Failure. Sleep 2018, 41: a327-a328. DOI: 10.1093/sleep/zsy061.880.
- Trivedi V, Zinchuk A, Qin L, Bravata D, Strohl K, Selim B, Yaggi H. 0574 A Composite Model of Commonly Derived Polysomnographic Variables Predicts Risk of Cardiovascular Outcomes Better than the Apnea Hypopnea Index Alone. Sleep 2018, 41: a213-a214. DOI: 10.1093/sleep/zsy061.573.
- Miner B, Hajduk A, Yaggi H, Fragoso C. 0734 Subjective-Objective Sleep Discrepancy in Older Adults. Sleep 2018, 41: a272-a273. DOI: 10.1093/sleep/zsy061.733.
- Miner B, Redeker N, Yaggi H, Van Ness P, Han L, Gill T, Fragoso C. 0755 LONGITUDINAL ASSOCIATIONS OF RISK FACTORS WITH INSOMNIA SEVERITY IN OLDER PERSONS. Sleep 2017, 40: a280-a280. DOI: 10.1093/sleepj/zsx050.754.
- Womack JA, Murphy TE, Bathulapalli H, Akgün KM, Gibert C, Kunisaki KM, Rimland D, Rodriguez-Barradas M, Yaggi H, Justice AC, Redeker NS. Sleep Disturbance Among HIV-Infected and Uninfected Veterans. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2017, 74: e117-e120. PMID: 27906767, PMCID: PMC5326673, DOI: 10.1097/qai.0000000000001264.
- Redeker NS, Knies AK, Hollenbeak C, Yaggi H, Cline J, Andrews L, Jacoby D, Sullivan A, O'Connell M, Iennaco J, Finoia L, Jeon S. Cognitive behavioral therapy for insomnia in stable heart failure: Protocol for a randomized controlled trial. Contemporary Clinical Trials 2017, 55: 16-23. PMID: 28159703, PMCID: PMC5348292, DOI: 10.1016/j.cct.2017.01.009.
- Koo BB, Won C, Selim BJ, Qin L, Jeon S, Redeker NS, Bravata DM, Strohl KP, Concato J, Zinchuk AV, Yaggi HK. The Determining Risk of Vascular Events by Apnea Monitoring (DREAM) study: design, rationale, and methods. Sleep And Breathing 2015, 20: 893-900. PMID: 26642771, DOI: 10.1007/s11325-015-1254-3.
- Koo B, Yaggi H, Qin L, Tobias L, Bravata D. Abstract W P167: Obstructive Sleep Apnea in Wake-Up Stroke. Stroke 2015, 46 DOI: 10.1161/str.46.suppl_1.wp167.
- Sharifi H, Sands M, Bernardo S, Strohl K, Ferguson J, Jimenez W, Qin L, Bennett A, Doctor K, Struve F, Bravata D, Yaggi H. The Association of Opioid Use, Sleep-Disordered Breathing, and Mortality in the DREAM Study. CHEST Journal 2014, 146: 959a. DOI: 10.1378/chest.1988052.
- Kunisaki K, Akgün K, Fiellin D, Gibert C, Kim J, Rimland D, Rodriguez‐Barradas M, Yaggi H, Crothers K. OSA and HIV infection. HIV Medicine 2014, 16: 105-113. PMID: 25230851, PMCID: PMC4300288, DOI: 10.1111/hiv.12182.
- Sico J, Ofner S, Qin L, Yaggi H, Bravata D. Abstract W P128: Development and Validation of Clinical Prediction Model for Obstructive Sleep Apnea among Patients with Ischemic Stroke and TIA. Stroke 2014, 45 DOI: 10.1161/str.45.suppl_1.wp128.
- Shah N, Kizer J, Yaggi H. Effects of Obstructive Sleep Apnea Therapy on Cardiovascular Disease. Sleep Medicine Clinics 2013, 8: 453-461. DOI: 10.1016/j.jsmc.2013.07.015.
- Shah N, Yaggi H, Redline S. Sex-related Differences in Cardiometabolic Outcomes Associated With Obstructive Sleep Apnea. Clinical Pulmonary Medicine 2013, 20: 149-154. DOI: 10.1097/cpm.0b013e31828fce1b.
- Sico J, Ofner S, Yaggi H, Bravata D. Abstract WP189: Prediction of Apnea Hypopnea Index among Stroke and TIA Patients. Stroke 2013, 44 DOI: 10.1161/str.44.suppl_1.awp189.
- Addison-Brown K, Letter A, Yaggi H, McClure L, Unverzagt F, Howard V, Lichtman J, Wadley V. Abstract WP445: Age Differences in the Impact of Sleep Apnea on Cognition and Quality of Life. Stroke 2013, 44 DOI: 10.1161/str.44.suppl_1.awp445.
- Schmid A, Yaggi H, Burrus N, McClain V, Austin C, Ferguson J, Fragoso C, Sico J, Ofner S, Miech E, Matthias M, Williams L, Bravata D. Abstract TP318: The Circumstances and Consequences of Post-stroke Falls. Stroke 2013, 44 DOI: 10.1161/str.44.suppl_1.atp318.
- Shah N, Redline S, Yaggi H, Wu R, Zhao C, Ostfeld R, Menegus M, Tracy D, Brush E, Appel W, Kaplan R. Erratum to: Obstructive sleep apnea and acute myocardial infarction severity: ischemic preconditioning? Sleep And Breathing 2012, 17: 1119-1119. DOI: 10.1007/s11325-012-0793-0.
- Knauert M, Yaggi H, Redeker N, Murphy T, Araujo K, Pisani M. Sources of Overnight Patient Sleep Disruption in the Medical Intensive Care Unit. CHEST Journal 2012, 142: 547a-547b. DOI: 10.1378/chest.1383037.
- Bravata D, Sico J, Phipps M, Yaggi H. Response to ambulatory blood pressure monitoring in acute stroke. Blood Pressure Monitoring 2012, 17: 221-222. DOI: 10.1097/mbp.0b013e328358d95a.
- Dieffenbach P, Bravata D, Ferguson J, McClain V, Austin C, Struve F, Li X, Williams L, Sico J, Fragoso C, Burrus N, Concato J, Kim N, Yaggi H. Investigating the Healthy User Effect: Correlating CPAP Use and Medication Adherence. CHEST Journal 2012, 142: 1053a-1053c. DOI: 10.1378/chest.1386770.
- Bravata D, Yaggi H. Response to the Letter to the Editor from Parra and Arboix. Sleep 2012, 35: 749-749. PMCID: PMC3353050, DOI: 10.5665/sleep.1862.
- Knauert-Brown M, Yaggi H, Redeker N, Murphy T, Araujo K, Donlon T, Pisani M. Feasibility Of Conducting 24-Hour Polysomnography Studies In The Medical Intensive Care Unit. 2012, a1617-a1617. DOI: 10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a1617.
- Yaggi H, Dieffenbach P. Chapter 51 Sleep-Disordered Breathing and Cerebrovascular Disease. 2012, 647-655. DOI: 10.1016/b978-1-4377-1703-7.10051-9.
- Fragoso C, Gill TM, McAvay G, Van Ness PH, Yaggi HK, Concato J. Use of Lambda-Mu-Sigma-Derived Z Score for Evaluating Respiratory Impairment in Middle-Aged Persons. Respiratory Care 2011, 56: 1771-1777. PMID: 21605489, PMCID: PMC3676885, DOI: 10.4187/respcare.01192.
- Yaggi H. Sleep Apnea and Cerebrovascular Disorders. 2011, 302-310. DOI: 10.2174/978160805153311101010302.
- Dieffenbach P, Yaggi H. The Role of Obstructive Sleep Apnea in Type 2 Diabetes. International Journal Of Clinical Reviews 2011 DOI: 10.5275/ijcr.2011.07.03.
- Shah N, Appel D, Kaplan R, Yaggi H. Obstructive Sleep Apnea And Severity Of Acute Myocardial Infarction: Ischemic Preconditioning? 2011, a2485-a2485. DOI: 10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a2485.
- Yaggi H, Chiong T, Mohsenin V. Preface. Clinics In Chest Medicine 2010, 31: xiii-xiv. DOI: 10.1016/j.ccm.2010.03.003.
- Auto-Titrating Continuous Positive Airway Pressure for Patients With Acute Transient Ischemic AttackBravata DM, Concato J, Fried T, Ranjbar N, Sadarangani T, McClain V, Struve F, Zygmunt L, Knight HJ, Lo A, Richerson GB, Gorman M, Williams LS, Brass LM, Agostini J, Mohsenin V, Roux F, Yaggi HK. Auto-Titrating Continuous Positive Airway Pressure for Patients With Acute Transient Ischemic Attack. Stroke 2010, 41: 1464-1470. PMID: 20508184, PMCID: PMC4567557, DOI: 10.1161/strokeaha.109.566745.
- Vaz Fragoso CA, Concato J, McAvay G, Van Ness PH, Rochester CL, Yaggi HK, Gill TM. The Ratio of FEV1 to FVC as a Basis for Establishing Chronic Obstructive Pulmonary Disease. American Journal Of Respiratory And Critical Care Medicine 2009, 181: 446-451. PMID: 20019341, PMCID: PMC3159085, DOI: 10.1164/rccm.200909-1366oc.
- Botros N, Concato J, Mohsenin V, Selim B, Doctor K, Yaggi HK. Obstructive Sleep Apnea as a Risk Factor for Type 2 Diabetes. The American Journal Of Medicine 2009, 122: 1122-1127. PMID: 19958890, PMCID: PMC2799991, DOI: 10.1016/j.amjmed.2009.04.026.
- Yaggi H, Concato J, Mohsenin V, McClain V, Fried T, Ranjbar N, Sadarangani T, Struve F, Zygmunt L, Lo A, Richerson G, Gorman M, Williams L, Brass L, Agostini J, Roux F, Bravata D. The Diagnosis and Treatment of Sleep Apnea among Patients with Transient Ischemic Attack: Results of a Feasibility Study. 2009, a3989. DOI: 10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a3989.
- Yaggi H, Concato J, Fried T, Ranjbar N, Sadarangani T, McClain V, Struve F, Zygmunt L, Lo A, Richerson G, Gorman M, Williams L, Brass L, Agostini J, Mohsenin V, Roux F, Bravata D. The Diagnosis and Treatment of Sleep Apnea among Patients with Acute Ischemic Stroke: Results of a Feasiblity Study. 2009, a5338. DOI: 10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a5338.
- Mohsenin V, Yaggi HK, Shah N, Dziura J. The effect of gender on the prevalence of hypertension in obstructive sleep apnea. Sleep Medicine 2009, 10: 759-762. PMID: 19185538, DOI: 10.1016/j.sleep.2008.09.005.
- Yaggi H. Sleep and the Cardiovascular System. 2009, 123-132. DOI: 10.1378/smbr.4th.123.
- Yaggi H. Obstructive Sleep Apnea-Hypopnea Syndrome: Definitions, Epidemiology, and Pathogenesis. 2009, 185-192. DOI: 10.1378/smbr.4th.185.
- Sands M, Botros N, Lichtman J, Yaggi H. RACIAL DIFFERENCES IN OBSTRUCTIVE SLEEP APNEA AND RISK OF HYPERTENSION. CHEST Journal 2008, 134: s51003-a-s51003-b. DOI: 10.1378/chest.134.4_meetingabstracts.s51003.
- Fragoso C, McAvay G, Van Ness P, Yaggi H, Rochester C, Concato J, Gill T. DEFINING CHRONIC OBSTRUCTIVE PULMONARY DISEASE IN OLDER PERSONS. CHEST Journal 2008, 134: s27003-a-s27003-b. DOI: 10.1378/chest.134.4_meetingabstracts.s27003.
- Yaggi H, Mohsenin V. Sleep Apnea and Stroke: A Risk Factor or an Association? Sleep Medicine Clinics 2007, 2: 583-591. DOI: 10.1016/j.jsmc.2007.07.004.
- Yaggi H, Mohsenin V. ELECTRIC AND MAGNETIC FIELDS. 2006, 88-91. DOI: 10.1201/b14948-16.
- Yaggi HK, Concato J, Kernan WN, Lichtman JH, Brass LM, Mohsenin V. Obstructive Sleep Apnea as a Risk Factor for Stroke and Death. New England Journal Of Medicine 2005, 353: 2034-2041. PMID: 16282178, DOI: 10.1056/nejmoa043104.
- Mohsenin V, Yaggi H. Sleep Apnea and Cerebrovascular Disease. 2005, 287-292. DOI: 10.1002/0471751723.ch38.
- Araujo A, Yaggi H, McKinlay J. Sleep duration and risk of diabetes in middle-aged and older men: prospective results from the Massachusetts male aging study. Annals Of Epidemiology 2004, 14: 598. DOI: 10.1016/j.annepidem.2004.07.019.
Locations
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- Yale Sleep Medicine Centers1291 Boston Post RoadMadison, CT 06443
- Yale Sleep Medicine Centers8 Devine StreetNorth Haven, CT 06473
Biography
Henry Yaggi, MD, MPH, is director of the Sleep Medicine Program and a specialist in pulmonary, critical care, and sleep medicine.
Dr. Yaggi’s patient care and research focuses on the intersection between sleep medicine and other specialties, including cardiovascular health, metabolic health, and cognitive function.
He often treats patients with sleep apnea, a sleeping disorder in which breathing stops and starts frequently during the night. His research explores many aspects of sleep apnea, including why it raises risk for cardiovascular and metabolic health issues and how at-home diagnosis and treatment of sleep apnea impacts cardiovascular risk.
Dr. Yaggi’s goal is to emphasize to his patients how important sleep is for their overall health and well-being and to make treatment for sleep disorders more accessible. Some of his research looks at how cognitive behavioral therapy can help patients who have insomnia and heart failure.
He is also a principal investigator at the National VA Clinical Epidemiology Research Center.
Titles
- Professor of Internal Medicine (Pulmonary, Critical Care & Sleep Medicine)
- Vice Chief of Research, Pulmonary, Critical Care & Sleep Medicine
- Director, Yale Centers for Sleep Medicine, Pulmonary, Critical Care & Sleep Medicine
Education & Training
- FellowYale-New Haven Hospital (2003)
- MPHYale School of Public Health, Chronic Disease Epidemiology (2003)
- VA Clinical Scholar Research FellowYale University (2000)
- ResidentYale-New Haven Hospital (1999)
- MDUniversity of Maryland/Baltimore County (1996)
- BAJohns Hopkins University (1992)
Additional Information
Honors & Recognitions
- Mentee Andrey Zinchuk, 12th Annual Young Investigators Award: Respiratory Disease Forum (2019)
- Mentee Andrey Zinchuk selected as Young investigator of the Year: Associated Professional Sleep Society, National SLEEP Meeting (2018)
- "Cardiovascular Phenotypes and their Cardiovascular Implications" cited as a top 10 article of the year: Associated Professional Sleep Society, National SLEEP Meeting (2018)
- "Cardiovascular phenotypes and their cardiovascular implication in Obstructive Sleep Apnea" Highlighted paper: British Thoracic Society (2017)
- Faculty Achievement Award for Accomplishment in Research: Yale University School of Medicine, Department of Medicine (2010)
- Ralph Horowitz Annual Lecturer in Clinical Epidemiology: Yale University School of Medicine, Department of Medicine (2010)
- Advanced Career Development Award: VA Clinical Science Research and Development Service (2008)
- A Top 5 Cited Article in Sleep Medicine, “Obstructive Sleep Apnea as a Risk Factor for Stroke and Death” cited by American: American Thoracic Society (2006)
- “The Year in Medicine from A to Z” ; (cited our research related to obstructive sleep apnea and stroke). Highlighted on Today Show.: Time Magazine (2005)
- Master’s Thesis with Honors in Public Health: Yale University School of Epidemiology and Public Health (2003)
Board Certifications
- AB of Internal Medicine, Critical Care Medicine (Internal Medicine) (2006, recertified: 2020)
- AB of Sleep Medicine, Sleep Medicine (2004)
Professional Service
- NIH/NHLBI (U01) "New Epidemiology Cohort Studies in Heart, Lung, Blood and Sleep Disorders" (2019): Committee Member
- Sleep in Heavenly Peace (Construction of Beds for Children in New Haven) (2019 - Present): Participant
- New Haven Bed Race, Fundraiser for the Connecticut Burns Care Foundation (2018 - Present): Volunteer
- CHEST, Sleep Medicine Board Review Course, Pheonix, AZ (2017 - 2019): Chair
- Bayer Pharmaceuticals (2017): Committee Member
- Closer to Free Ride, Fundraiser for Smilow Cancer Center (2017 - Present): Participant
- ALA Autumn Trek, Fundraiser for the American Lung Association (2016 - Present): Participant
- Yale Center for Clinical Investigation (YCCI), Study Section for YCCI Clinical and Community Research Scholar Awards (2015 - 2017): Committee Member
- CHEST Sleep Medicine Board Review Course, Orlando, FL (2015 - 2017): Co-Chair
- Research Advisory Panel, Food and Drug Administration, Upper Airway Neurostimulation for the Treatment of Obstructive Sleep Apnea (2014): Member
Publications
- Knauert M, Adekolu O, Xu Z, Deng A, Chu J, Baldassarri S, Kushida C, Yaggi H, Zinchuk A. Morning Chronotype Is Associated with Improved Adherence to Continuous Positive Airway Pressure among Individuals with Obstructive Sleep Apnea. Annals Of The American Thoracic Society 2023, 20: 1182-1191. PMID: 36917194, PMCID: PMC10405611, DOI: 10.1513/annalsats.202210-885oc.
- Redeker N, Conley S, O'Connell M, Geer J, Yaggi H, Jeon S. Sleep-related predictors of cognition among adults with chronic insomnia and heart failure enrolled in a randomized controlled trial of cognitive behavioral therapy for insomnia. Journal Of Clinical Sleep Medicine 2023, 19: 1073-1081. PMID: 36740924, PMCID: PMC10235706, DOI: 10.5664/jcsm.10498.
- Aneni E, Saeed G, Thorn S, Miller E, Sinusas A, Yaggi H. 0488 The Relationship between Myocardial Blood Flow and Diastolic Function in a Clinical Population with Obstructive Sleep Apnea. Sleep 2023, 46: a217-a217. DOI: 10.1093/sleep/zsad077.0488.
- Miner B, Pan Y, Burzynski C, Iannone L, Knauert M, Gill T, Yaggi H. 0726 Agreement Between an Electroencephalography-Measuring Headband and Polysomnography in Older Adults with Sleep Disturbances. Sleep 2023, 46: a319-a320. DOI: 10.1093/sleep/zsad077.0726.
- Lukas M, Doyle M, Intihar T, Wright K, Redeker N, Pisani M, Yaggi H, Knauert M. 0841 Feasibility of Actigraphy during a Daytime Bright Pilot Study in the Medical ICU. Sleep 2023, 46: a370-a371. DOI: 10.1093/sleep/zsad077.0841.
- Intihar T, Doyle M, Lukas M, Wright K, Redeker N, Pisani M, Yaggi H, Knauert M. 0842 Feasibility of daytime bright light exposure and urinary 6-sulfatoxymelatonin profiling in the medical ICU: A pilot study. Sleep 2023, 46: a371-a371. DOI: 10.1093/sleep/zsad077.0842.
- Walker A, Baldassarri S, Chu J, Deng A, Xu Z, Blohowiak R, Byrne S, Kushida C, Yaggi H, Zinchuk A. 0480 Psychoactive Substance Use and Sleep Characteristics Among Individuals with Untreated Obstructive Sleep Apnea. Sleep 2023, 46: a213-a214. DOI: 10.1093/sleep/zsad077.0480.
- Jeon S, Conley S, Hollenbeak C, O’Connell M, Yaggi H, Jacoby D, Wang Z, Tocchi C, Redeker N. 0395 Effects of Insomnia and Rest-Activity on Hospitalizations and Emergency Department Visits in People with Stable Heart Failure. Sleep 2023, 46: a175-a175. DOI: 10.1093/sleep/zsad077.0395.
- Nwanaji-Enwerem U, Sadler L, Jeon S, Barry D, Yaggi H, Redeker N. 0144 A Mixed Methods Exploration of Stigma, Discrimination, and Sleep among Individuals on Medication for Opioid Use Disorder. Sleep 2023, 46: a65-a65. DOI: 10.1093/sleep/zsad077.0144.
- Cox R, Haller S, Martinez-Lisowska Z, Kuppa A, Sprecher K, Withrow D, Barry D, Scheinost D, Redeker N, Yaggi H, Wright K. 0677 Blunted daily light rhythm amplitude in adults with opioid use disorder (OUD). Sleep 2023, 46: a297-a298. DOI: 10.1093/sleep/zsad077.0677.
- Mehta S, Peterson H, Ibrahim A, Saeed G, Linsky S, Kreinin I, Tsang S, Nwanaji-Enwerem U, Raso A, Barry D, Redeker N, Yaggi H, Scheinost D. 350. Brain Volume Alterations in Individuals With Opioid Use Disorder. Biological Psychiatry 2023, 93: s235. DOI: 10.1016/j.biopsych.2023.02.590.
- Baldassarri S, Chu J, Deng A, Xu Z, Blohowiak R, Byrne S, Kushida C, Yaggi H, Zinchuk A. Nicotine, alcohol, and caffeine use among individuals with untreated obstructive sleep apnea. Sleep And Breathing 2023, 27: 2479-2490. PMID: 37058215, PMCID: PMC10576010, DOI: 10.1007/s11325-023-02830-3.
- Wojeck B, Inzucchi S, Qin L, Yaggi H. Polysomnographic predictors of incident diabetes and pre-diabetes: an analysis of the DREAM study. Journal Of Clinical Sleep Medicine 2023, 19: 703-710. PMID: 36689314, PMCID: PMC10071389, DOI: 10.5664/jcsm.10414.
- Aneni E, Thorn S, Feher A, Hong Chen J, Sinusas A, Yaggi H, Miller E. The Association Between Obstructive Sleep Apnea and Abnormal 82Rubidium Cardiac PET Perfusion Myocardial Flow Reserve. JACC Cardiovascular Imaging 2023, 16: 856-858. PMID: 36881426, PMCID: PMC10718199, DOI: 10.1016/j.jcmg.2022.11.024.
- Geer J, Karagoz E, Yaggi H. Sleep apnea and stroke. 2023, 271-277. DOI: 10.1016/b978-0-12-822963-7.00325-x.
- Miner B, Doyle M, Knauert M, Yaggi H, Stone K, Ancoli‐Israel S, Cauley J, Redline S, Blackwell T, Gill T, Groups F. Insomnia with objective short sleep duration in community‐living older persons: A multifactorial geriatric health condition. Journal Of The American Geriatrics Society 2022, 71: 1198-1208. PMID: 36524599, PMCID: PMC10089942, DOI: 10.1111/jgs.18195.
- Dreyer R, Berkowitz A, Yaggi H, Schneeberg L, Shah N, Emanuel L, Prakash K, Jeffery M, Thorndike F, Deeg M, Ervin K, Ross J. PreScription DigitaL ThErapEutic For Patients with Insomnia (SLEEP-I): A Protocol for a Pragmatic Randomized Controlled Trial. Sleep Medicine 2022, 100: s133-s134. DOI: 10.1016/j.sleep.2022.05.365.
- Aneni E, Chen J, Thorn S, Miller E, Sinusas A, Yaggi H. Obstructive Sleep Apnea Severity is Associated with Abnormal Myocardial 82Rubidium PET Blood Flow Reserve. Sleep Medicine 2022, 100: s261. DOI: 10.1016/j.sleep.2022.05.703.
- Wojeck B, Inzucchi S, Neeland I, Mancuso J, Frederich R, Masiukiewicz U, Cater N, McGuire D, Cannon C, Yaggi H. Ertugliflozin and Incident Obstructive Sleep Apnea: An Analysis from the VERTIS CV Trial. Sleep Medicine 2022, 100: s249-s250. DOI: 10.1016/j.sleep.2022.05.671.
- Saeed G, Aneni E, Otite F, Thorn S, Miller E, Sinusas A, Yaggi H. Abstract 14839: Clinical, Polysomnographic and Echocardiographic Correlates of Excessive Daytime Sleepiness. Circulation 2022, 146: a14839-a14839. DOI: 10.1161/circ.146.suppl_1.14839.
- Aneni E, Miller E, Saeed G, deKemp R, KLEIN R, Beanlands R, Yaggi H, Sinusas A, Thorn S. Abstract 13798: Obstructive Sleep Apnea Severity and Abnormal Right Ventricular Flow Reserve in Adult OSA Patients Who Received Rubidium-82 Cardiac PET Perfusion Imaging. Circulation 2022, 146: a13798-a13798. DOI: 10.1161/circ.146.suppl_1.13798.
- Hollenbeak C, Jeong S, O'Connell M, Redeker N, Yaggi H. Abstract 10200: Costs and Resource Utilization of People With Stable Heart Failure and Insomnia: Evidence From a Randomized Trial. Circulation 2022, 146: a10200-a10200. DOI: 10.1161/circ.146.suppl_1.10200.
- Sharma A, Byrne S, Deng A, Chu J, Sands S, Wellman A, Redeke N, Yaggi H, Zinchuk A. 0158 Risk perception, outcome expectancy, and treatment self-efficacy among women and men with obstructive sleep apnea (OSA). Sleep 2022, 45: a73-a73. DOI: 10.1093/sleep/zsac079.156.
- Byrne S, Sharma A, Deng A, Chu J, Sands S, Wellman A, Redeker N, Yaggi H, Zinchuk A. 0790 Racial Differences in Self-Efficacy for Positive Airway Pressure Therapy Among Individuals Newly Diagnosed with Obstructive Sleep Apnea. Sleep 2022, 45: a343-a343. DOI: 10.1093/sleep/zsac079.786.
- Miner B, Yaggi H, Gill T, Doyle M, Stone K, Redline S, Ensrud K, Blackwell T, Knauert M. 0321 Poor Agreement Among Self-Reported and Objective Sleep Deficiency Assessments in Older Persons. Sleep 2022, 45: a144-a145. DOI: 10.1093/sleep/zsac079.319.
- Miner B, Stone KL, Zeitzer JM, Han L, Doyle M, Blackwell T, Gill TM, Redeker NS, Hajduk A, Yaggi H. Self-reported and actigraphic short sleep duration in older adults. Journal Of Clinical Sleep Medicine 2022, 18: 403-413. PMID: 34338629, PMCID: PMC8804982, DOI: 10.5664/jcsm.9584.
- Ding Q, Qin L, Wojeck B, Inzucchi SE, Ibrahim A, Bravata DM, Strohl KP, Yaggi HK, Zinchuk AV. Polysomnographic Phenotypes of Obstructive Sleep Apnea and Incident Type 2 Diabetes: Results from the DREAM Study. Annals Of The American Thoracic Society 2021, 18: 2067-2078. PMID: 34185617, PMCID: PMC8641817, DOI: 10.1513/annalsats.202012-1556oc.
- Ding Q, Qin L, Wojeck B, Inzucchi S, Ibrahim A, Bravata D, Strohl K, Yaggi H, Zinchuk A. Associations Between Polysomnographic Phenotypes of Obstructive Sleep Apnea and Incident Type 2 Diabetes. 2021, a4679-a4679. DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a4679.
- Adekolu O, Xu Z, Chu J, Kushida C, Yaggi H, Knauert M, Zinchuk A. 441 Influence Of Chronotype On CPAP Adherence. Sleep 2021, 44: a174-a175. DOI: 10.1093/sleep/zsab072.440.
- Kunitomo Y, Lee M, DeRycke E, Yaggi H, Bastian L. Prevalence of Obstructive Sleep Apnea in a Cohort of Veterans with Chronic Pain and Active Smoking History. 2021, a1564-a1564. DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1564.
- Redeker N, Bessette A, Breazeale S, Conley S, Hollenbeak C, Hwang Y, Iannacco J, Jacoby D, Kelly-Hauser J, Linsky S, Moemeka L, Nwanaji-Enwerem U, O’Connell M, Yaggi H, Jeon S. 342 CBT-I Has Sustained Effects on Insomnia Versus Heart-Failure Self-Management Education among Adults with Chronic Heart Failure. Sleep 2021, 44: a136-a137. DOI: 10.1093/sleep/zsab072.341.
- Zinchuk A, Yaggi H. Treatment-Emergent Central Sleep Apnea. 2021, 85-102. DOI: 10.1007/978-3-030-57942-5_8.
- Anker S, Fitchett D, Zinman B, Ofstad A, Wanner C, Vedin O, Schinzel B, Yaggi H, George J, Sander L, Inzucchi S, Verma S. Abstract 14962: Empagliflozin’s Cardiovascular Impact in High-Risk Patients With Type 2 Diabetes and Obstructive Pulmonary Disease: An Inquiry From EMPA-REG OUTCOME. Circulation 2020, 142 DOI: 10.1161/circ.142.suppl_3.14962.
- Yaggi H, Eliasson B, Kasai T, Marx N, Zinman B, Inzucchi S, Wanner C, Zwiener I, Wojeck B, Neeland I, Johansen O. Obstructive sleep apnoe and cardiovascular, heart failure and mortality outcomes with empagliflozin versus placebo in the EMPA-REG OUTCOME trial. European Heart Journal 2020, 41 DOI: 10.1093/ehjci/ehaa946.2883.
- NEELAND I, ELIASSON B, KASAI T, MARX N, ZINMAN B, INZUCCHI S, WANNER C, ZWIENER I, WOJECK B, YAGGI H, JOHANSEN O. 1128-P: Empagliflozin and Obstructive Sleep Apnea (OSA): Exploratory Analysis from the EMPA-REG OUTCOME Trial. Diabetes 2020, 69 DOI: 10.2337/db20-1128-p.
- Miner B, Fragoso C, Han L, Yaggi H, Redeker N, Stone K. 0852 Geriatric Health Conditions And The Combined Outcome Of Poor Sleep Quality With Objective Short Sleep Duration. Sleep 2020, 43: a324-a325. DOI: 10.1093/sleep/zsaa056.848.
- Miner B, Fragoso C, Han L, Stone K, Redeker N, Yaggi H. 0855 Primary Sleep Disorders And The Combined Outcome Of Poor Sleep Quality With Objective Short Sleep Duration In Older Persons. Sleep 2020, 43: a325-a326. DOI: 10.1093/sleep/zsaa056.851.
- Zinchuk A, Yaggi H, Liang J, Chu J, De Beeck S, Stepnowski C, Wellman A, Peker Y, Sands S. 0568 Physiologic OSA Traits and CPAP Adherence Among Patients with Coronary Artery Disease and OSA. Sleep 2020, 43: a218-a218. DOI: 10.1093/sleep/zsaa056.565.
- Liu J, Yaggi H. Maximal Airflow Increase Rate (MAFIR): A New Metric of Arousal Threshold and a Cause of Respiratory Arousal. 2020, a6455-a6455. DOI: 10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a6455.
- Geer J, Vanent K, Leasure A, Pisani M, Sansing L, Woo D, Langefeld C, Falcone G, Sheth K, Yaggi H. Obstructive Sleep Apnea: A Prevalent and Novel Risk Factor for Intracerebral Hemorrhage. 2020, a2713-a2713. DOI: 10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a2713.
- Yaggi H, Eliasson B, Kasai T, Marx N, Zinman B, Inzucchi S, Wanner C, Zwiener I, Wojeck B, Neeland I, Johansen O. Obstructive Sleep Apnoe and Cardiovascular, Heart Failure and Mortality Outcomes with Empagliflozin Versus Placebo in the EMPA-REG Outcome ® Trial. 2020, a4713-a4713. DOI: 10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a4713.
- Zinchuk A, Yaggi H, Liang J, Chu J, Op de Beeck S, Stepnowsky C, Wellman D, Peker Y, Sands S. Physiologic Traits Predict Therapeutic Pressure Requirements and Residual Respiratory Events Among Patients with Coronary Artery Disease and Obstructive Sleep Apnea. 2020, a6439-a6439. DOI: 10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a6439.
- Geer J, Leasure A, Vanent K, Sansing L, Woo D, Langefeld C, Yaggi H, Falcone G, Sheth K. Abstract TP347: Obstructive Sleep Apnea Frequency in Intracerebral Hemorrhage. Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.tp347.
- Zinchuk A, Yaggi H, Concato J, Jeon S, Bravata D, Wellman D, Sands S. Low Arousal Threshold Correlates with Reduced Continuous Positive Airway Pressure Use in Non-Obese Individuals with Obstructive Sleep Apnea and Stroke. 2019, a2598-a2598. DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2598.
- Zinchuk A, Yaggi H, Concato J, Wellman D, Smales E, Hess L, Denos J, Peker Y, Sands S. Effect of Arousal Scoring on Reliability of Automated, Non-Invasive Phenotyping of Physiologic Sleep Apnea Traits from Polysomnography. 2019, a7078-a7078. DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7078.
- Liu J, Qin L, Yaggi H. 0138 Physiological Effects of Respiratory Events that Terminate Without Arousals During Sleep. Sleep 2019, 42: a56-a57. DOI: 10.1093/sleep/zsz067.137.
- Liu J, Qin L, McConaughey C, Yaggi H. 0494 Associations of Obstructive Sleep Apnea with Renal Function Decline in a Cohort of Veterans. Sleep 2019, 42: a198-a198. DOI: 10.1093/sleep/zsz067.492.
- Miner B, MHS M, Stone K, Hajduk A, Yaggi H, Redeker N, Fragoso C. 0709 Self-Reported and Actigraphic Short Sleep Duration in Older Persons. Sleep 2019, 42: a284-a285. DOI: 10.1093/sleep/zsz067.707.
- Liu J, Yaggi H. Characterization of Arousals in Polysomnography Using the Statistical Significance of Power Change. 2018, 00: 1-6. DOI: 10.1109/spmb.2018.8615603.
- Zinchuk A, Jeon S, Yaggi H. 0466 High Frequency Of PLMS Is Associated With Increased Risk Of Incident Adverse Cardiovascular Events And Death Among OSA Patients. Sleep 2018, 41: a176-a176. DOI: 10.1093/sleep/zsy061.465.
- Williams C, Yaggi H, Kuna S, Asare V. 0943 Dream Enactment Behavior in Post Traumatic Stress Disorder Patients. Sleep 2018, 41: a350-a350. DOI: 10.1093/sleep/zsy061.942.
- Conley S, Jeon S, Yaggi H, Jacoby D, Hollenbeak C, O’Connell M, Linsky S, Darden J, Gaiser E, Kelly-Hauser J, Matthew B, Richardson P, Redeker N. 0881 Insomnia Is Related To Self-care In People With Stable Heart Failure. Sleep 2018, 41: a327-a328. DOI: 10.1093/sleep/zsy061.880.
- Trivedi V, Zinchuk A, Qin L, Bravata D, Strohl K, Selim B, Yaggi H. 0574 A Composite Model of Commonly Derived Polysomnographic Variables Predicts Risk of Cardiovascular Outcomes Better than the Apnea Hypopnea Index Alone. Sleep 2018, 41: a213-a214. DOI: 10.1093/sleep/zsy061.573.
- Miner B, Hajduk A, Yaggi H, Fragoso C. 0734 Subjective-Objective Sleep Discrepancy in Older Adults. Sleep 2018, 41: a272-a273. DOI: 10.1093/sleep/zsy061.733.
- Miner B, Redeker N, Yaggi H, Van Ness P, Han L, Gill T, Fragoso C. 0755 LONGITUDINAL ASSOCIATIONS OF RISK FACTORS WITH INSOMNIA SEVERITY IN OLDER PERSONS. Sleep 2017, 40: a280-a280. DOI: 10.1093/sleepj/zsx050.754.
- Womack JA, Murphy TE, Bathulapalli H, Akgün KM, Gibert C, Kunisaki KM, Rimland D, Rodriguez-Barradas M, Yaggi H, Justice AC, Redeker NS. Sleep Disturbance Among HIV-Infected and Uninfected Veterans. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2017, 74: e117-e120. PMID: 27906767, PMCID: PMC5326673, DOI: 10.1097/qai.0000000000001264.
- Redeker NS, Knies AK, Hollenbeak C, Yaggi H, Cline J, Andrews L, Jacoby D, Sullivan A, O'Connell M, Iennaco J, Finoia L, Jeon S. Cognitive behavioral therapy for insomnia in stable heart failure: Protocol for a randomized controlled trial. Contemporary Clinical Trials 2017, 55: 16-23. PMID: 28159703, PMCID: PMC5348292, DOI: 10.1016/j.cct.2017.01.009.
- Koo BB, Won C, Selim BJ, Qin L, Jeon S, Redeker NS, Bravata DM, Strohl KP, Concato J, Zinchuk AV, Yaggi HK. The Determining Risk of Vascular Events by Apnea Monitoring (DREAM) study: design, rationale, and methods. Sleep And Breathing 2015, 20: 893-900. PMID: 26642771, DOI: 10.1007/s11325-015-1254-3.
- Koo B, Yaggi H, Qin L, Tobias L, Bravata D. Abstract W P167: Obstructive Sleep Apnea in Wake-Up Stroke. Stroke 2015, 46 DOI: 10.1161/str.46.suppl_1.wp167.
- Sharifi H, Sands M, Bernardo S, Strohl K, Ferguson J, Jimenez W, Qin L, Bennett A, Doctor K, Struve F, Bravata D, Yaggi H. The Association of Opioid Use, Sleep-Disordered Breathing, and Mortality in the DREAM Study. CHEST Journal 2014, 146: 959a. DOI: 10.1378/chest.1988052.
- Kunisaki K, Akgün K, Fiellin D, Gibert C, Kim J, Rimland D, Rodriguez‐Barradas M, Yaggi H, Crothers K. OSA and HIV infection. HIV Medicine 2014, 16: 105-113. PMID: 25230851, PMCID: PMC4300288, DOI: 10.1111/hiv.12182.
- Sico J, Ofner S, Qin L, Yaggi H, Bravata D. Abstract W P128: Development and Validation of Clinical Prediction Model for Obstructive Sleep Apnea among Patients with Ischemic Stroke and TIA. Stroke 2014, 45 DOI: 10.1161/str.45.suppl_1.wp128.
- Shah N, Kizer J, Yaggi H. Effects of Obstructive Sleep Apnea Therapy on Cardiovascular Disease. Sleep Medicine Clinics 2013, 8: 453-461. DOI: 10.1016/j.jsmc.2013.07.015.
- Shah N, Yaggi H, Redline S. Sex-related Differences in Cardiometabolic Outcomes Associated With Obstructive Sleep Apnea. Clinical Pulmonary Medicine 2013, 20: 149-154. DOI: 10.1097/cpm.0b013e31828fce1b.
- Sico J, Ofner S, Yaggi H, Bravata D. Abstract WP189: Prediction of Apnea Hypopnea Index among Stroke and TIA Patients. Stroke 2013, 44 DOI: 10.1161/str.44.suppl_1.awp189.
- Addison-Brown K, Letter A, Yaggi H, McClure L, Unverzagt F, Howard V, Lichtman J, Wadley V. Abstract WP445: Age Differences in the Impact of Sleep Apnea on Cognition and Quality of Life. Stroke 2013, 44 DOI: 10.1161/str.44.suppl_1.awp445.
- Schmid A, Yaggi H, Burrus N, McClain V, Austin C, Ferguson J, Fragoso C, Sico J, Ofner S, Miech E, Matthias M, Williams L, Bravata D. Abstract TP318: The Circumstances and Consequences of Post-stroke Falls. Stroke 2013, 44 DOI: 10.1161/str.44.suppl_1.atp318.
- Shah N, Redline S, Yaggi H, Wu R, Zhao C, Ostfeld R, Menegus M, Tracy D, Brush E, Appel W, Kaplan R. Erratum to: Obstructive sleep apnea and acute myocardial infarction severity: ischemic preconditioning? Sleep And Breathing 2012, 17: 1119-1119. DOI: 10.1007/s11325-012-0793-0.
- Knauert M, Yaggi H, Redeker N, Murphy T, Araujo K, Pisani M. Sources of Overnight Patient Sleep Disruption in the Medical Intensive Care Unit. CHEST Journal 2012, 142: 547a-547b. DOI: 10.1378/chest.1383037.
- Bravata D, Sico J, Phipps M, Yaggi H. Response to ambulatory blood pressure monitoring in acute stroke. Blood Pressure Monitoring 2012, 17: 221-222. DOI: 10.1097/mbp.0b013e328358d95a.
- Dieffenbach P, Bravata D, Ferguson J, McClain V, Austin C, Struve F, Li X, Williams L, Sico J, Fragoso C, Burrus N, Concato J, Kim N, Yaggi H. Investigating the Healthy User Effect: Correlating CPAP Use and Medication Adherence. CHEST Journal 2012, 142: 1053a-1053c. DOI: 10.1378/chest.1386770.
- Bravata D, Yaggi H. Response to the Letter to the Editor from Parra and Arboix. Sleep 2012, 35: 749-749. PMCID: PMC3353050, DOI: 10.5665/sleep.1862.
- Knauert-Brown M, Yaggi H, Redeker N, Murphy T, Araujo K, Donlon T, Pisani M. Feasibility Of Conducting 24-Hour Polysomnography Studies In The Medical Intensive Care Unit. 2012, a1617-a1617. DOI: 10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a1617.
- Yaggi H, Dieffenbach P. Chapter 51 Sleep-Disordered Breathing and Cerebrovascular Disease. 2012, 647-655. DOI: 10.1016/b978-1-4377-1703-7.10051-9.
- Fragoso C, Gill TM, McAvay G, Van Ness PH, Yaggi HK, Concato J. Use of Lambda-Mu-Sigma-Derived Z Score for Evaluating Respiratory Impairment in Middle-Aged Persons. Respiratory Care 2011, 56: 1771-1777. PMID: 21605489, PMCID: PMC3676885, DOI: 10.4187/respcare.01192.
- Yaggi H. Sleep Apnea and Cerebrovascular Disorders. 2011, 302-310. DOI: 10.2174/978160805153311101010302.
- Dieffenbach P, Yaggi H. The Role of Obstructive Sleep Apnea in Type 2 Diabetes. International Journal Of Clinical Reviews 2011 DOI: 10.5275/ijcr.2011.07.03.
- Shah N, Appel D, Kaplan R, Yaggi H. Obstructive Sleep Apnea And Severity Of Acute Myocardial Infarction: Ischemic Preconditioning? 2011, a2485-a2485. DOI: 10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a2485.
- Yaggi H, Chiong T, Mohsenin V. Preface. Clinics In Chest Medicine 2010, 31: xiii-xiv. DOI: 10.1016/j.ccm.2010.03.003.
- Auto-Titrating Continuous Positive Airway Pressure for Patients With Acute Transient Ischemic AttackBravata DM, Concato J, Fried T, Ranjbar N, Sadarangani T, McClain V, Struve F, Zygmunt L, Knight HJ, Lo A, Richerson GB, Gorman M, Williams LS, Brass LM, Agostini J, Mohsenin V, Roux F, Yaggi HK. Auto-Titrating Continuous Positive Airway Pressure for Patients With Acute Transient Ischemic Attack. Stroke 2010, 41: 1464-1470. PMID: 20508184, PMCID: PMC4567557, DOI: 10.1161/strokeaha.109.566745.
- Vaz Fragoso CA, Concato J, McAvay G, Van Ness PH, Rochester CL, Yaggi HK, Gill TM. The Ratio of FEV1 to FVC as a Basis for Establishing Chronic Obstructive Pulmonary Disease. American Journal Of Respiratory And Critical Care Medicine 2009, 181: 446-451. PMID: 20019341, PMCID: PMC3159085, DOI: 10.1164/rccm.200909-1366oc.
- Botros N, Concato J, Mohsenin V, Selim B, Doctor K, Yaggi HK. Obstructive Sleep Apnea as a Risk Factor for Type 2 Diabetes. The American Journal Of Medicine 2009, 122: 1122-1127. PMID: 19958890, PMCID: PMC2799991, DOI: 10.1016/j.amjmed.2009.04.026.
- Yaggi H, Concato J, Mohsenin V, McClain V, Fried T, Ranjbar N, Sadarangani T, Struve F, Zygmunt L, Lo A, Richerson G, Gorman M, Williams L, Brass L, Agostini J, Roux F, Bravata D. The Diagnosis and Treatment of Sleep Apnea among Patients with Transient Ischemic Attack: Results of a Feasibility Study. 2009, a3989. DOI: 10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a3989.
- Yaggi H, Concato J, Fried T, Ranjbar N, Sadarangani T, McClain V, Struve F, Zygmunt L, Lo A, Richerson G, Gorman M, Williams L, Brass L, Agostini J, Mohsenin V, Roux F, Bravata D. The Diagnosis and Treatment of Sleep Apnea among Patients with Acute Ischemic Stroke: Results of a Feasiblity Study. 2009, a5338. DOI: 10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a5338.
- Mohsenin V, Yaggi HK, Shah N, Dziura J. The effect of gender on the prevalence of hypertension in obstructive sleep apnea. Sleep Medicine 2009, 10: 759-762. PMID: 19185538, DOI: 10.1016/j.sleep.2008.09.005.
- Yaggi H. Sleep and the Cardiovascular System. 2009, 123-132. DOI: 10.1378/smbr.4th.123.
- Yaggi H. Obstructive Sleep Apnea-Hypopnea Syndrome: Definitions, Epidemiology, and Pathogenesis. 2009, 185-192. DOI: 10.1378/smbr.4th.185.
- Sands M, Botros N, Lichtman J, Yaggi H. RACIAL DIFFERENCES IN OBSTRUCTIVE SLEEP APNEA AND RISK OF HYPERTENSION. CHEST Journal 2008, 134: s51003-a-s51003-b. DOI: 10.1378/chest.134.4_meetingabstracts.s51003.
- Fragoso C, McAvay G, Van Ness P, Yaggi H, Rochester C, Concato J, Gill T. DEFINING CHRONIC OBSTRUCTIVE PULMONARY DISEASE IN OLDER PERSONS. CHEST Journal 2008, 134: s27003-a-s27003-b. DOI: 10.1378/chest.134.4_meetingabstracts.s27003.
- Yaggi H, Mohsenin V. Sleep Apnea and Stroke: A Risk Factor or an Association? Sleep Medicine Clinics 2007, 2: 583-591. DOI: 10.1016/j.jsmc.2007.07.004.
- Yaggi H, Mohsenin V. ELECTRIC AND MAGNETIC FIELDS. 2006, 88-91. DOI: 10.1201/b14948-16.
- Yaggi HK, Concato J, Kernan WN, Lichtman JH, Brass LM, Mohsenin V. Obstructive Sleep Apnea as a Risk Factor for Stroke and Death. New England Journal Of Medicine 2005, 353: 2034-2041. PMID: 16282178, DOI: 10.1056/nejmoa043104.
- Mohsenin V, Yaggi H. Sleep Apnea and Cerebrovascular Disease. 2005, 287-292. DOI: 10.1002/0471751723.ch38.
- Araujo A, Yaggi H, McKinlay J. Sleep duration and risk of diabetes in middle-aged and older men: prospective results from the Massachusetts male aging study. Annals Of Epidemiology 2004, 14: 598. DOI: 10.1016/j.annepidem.2004.07.019.
Locations
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- Yale Sleep Medicine Centers1291 Boston Post RoadMadison, CT 06443
- Yale Sleep Medicine Centers8 Devine StreetNorth Haven, CT 06473
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1 of 2
- Yale Sleep Medicine Centers1291 Boston Post RoadMadison, CT 06443
- Yale Sleep Medicine Centers8 Devine StreetNorth Haven, CT 06473