- Adult Emergency DepartmentYale New Haven Hospital20 York Street, Ste Pavilion 218New Haven, CT 06510
- Yale New Haven Hospital and Emergency DepartmentYale New Haven Hospital20 York StreetNew Haven, CT 06510
- New London Buprenorphine Clinic931 Bank StreetNew London, CT 06320
Gail D'Onofrio, MD, MS
Biography
Gail D’Onofrio, MD, MS, is an emergency medicine and addiction medicine specialist who is internationally known for her work in alcohol and other substance use disorders, and in gender variations in women with ischemic heart disease. She is the former physician-in-chief of emergency services at Yale New Haven Hospital and was the inaugural chair of the Department of Emergency Medicine at Yale School of Medicine.
Dr. D’Onofrio’s goals have always been to provide quality medical care for the wide range of people who come through the emergency department (ED) doors, whether that means resuscitating and stabilizing critically ill or injured patients, or assessing and treating nonemergent illness or injuries.
“The ED offers access to care for all—all day, all night, every day,” she says. “Our goal Is to treat the presenting problem and make connections to any services or resources our patients might need, whether they have an acute illness or injury, an addiction, or exacerbation of chronic disease such as diabetes or hypertension.”
In addition to her role as Albert E. Kent professor of emergency medicine at Yale School of Medicine, Dr. D’Onofrio holds professorships in chronic disease epidemiology in Yale School of Public Health, and in internal medicine (core faculty in addiction).
For the past 30 years she has developed and tested interventions for alcohol, opioids, and other substance use disorders, serving as the principal investigator (PI) on several large National Institutes of Health (NIH), Substance Abuse and Mental Health Services Administration (SAMSHA), and Centers for Disease Control and Prevention (CDC) studies. Her research demonstrating that ED-initiated buprenorphine increases engagement in addiction treatment for people with opioid use disorder changed clinical practice.
Dr. D’Onofrio is also a founding member of the Board of Addiction Medicine, which is now recognized by the American Board of Medical Specialties as a specialty and subspecialty through Preventive Medicine. She has worked on the state and national levels and with multiple agencies to change policies and introduce interventions to combat the opioid crisis.
Titles
- Albert E. Kent Professor of Emergency Medicine, Professor of Epidemiology (Chronic Diseases) and Professor of Medicine Core Addiction
Education & Training
- FellowSAMSHA (1997)
- ResidentBoston City Hospital (1991)
- MDBoston University School of Medicine (1987)
- MSBoston University (1975)
Additional Information
- Distinguished Alumni Award: Boston University (2022)
- Distinguished Service Award: Association of Academic Chairs of Emergency Medicine (2022)
- AB of Preventive Medicine, Addiction Medicine (Preventive Medicine) (2018)
- AB of Emergency Medicine, Emergency Medicine (1992, recertified: 2011)
- Joseph D, Brokowski C, D'Onofrio G, Bogucki S, McGovern J, Allen R, Dziura J, Cone D, Pantalon M. "SafetyNet": Evaluation of a Recovery Coach and Paramedic Intervention Following Naloxone Resuscitation From an Opioid Overdose. Substance Use & Addiction Journal 2024, 29767342241266412. PMID: 39171791, DOI: 10.1177/29767342241266412.
- Howell B, Black A, Lin H, Lauretta G, Heimer R, Hawk K, D'Onofrio G, Fiellin D, Becker W. T50 Receipt of Prescribed Opioids and Benzodiazepines After Non-Fatal Overdose and Risk of Subsequent Overdose. Drug And Alcohol Dependence 2024, 260: 110499. DOI: 10.1016/j.drugalcdep.2023.110499.
- Hawk K, D'Onofrio G, Chawarski M, Coupet E, Cowan E, Curry L, Freiermurth C, Lyons M, Murphy A, O'Connor P, Richardson L, Rothman R, Whiteside L, Williams J, Fiellin D, Edelman E. W81 Implementation Facilitation Improves Clinician Readiness to Provide Emergency Department-Initiated Buprenorphine in Four Urban Academic Centers. Drug And Alcohol Dependence 2024, 260: 110699. DOI: 10.1016/j.drugalcdep.2023.110699.
- D’Onofrio G, Herring A, Perrone J, Hawk K, Samuels E, Cowan E, Anderson E, McCormack R, Huntley K, Owens P, Martel S, Schactman M, Lofwall M, Walsh S, Dziura J, Fiellin D. Extended-Release 7-Day Injectable Buprenorphine for Patients With Minimal to Mild Opioid Withdrawal. JAMA Network Open 2024, 7: e2420702. PMID: 38976265, PMCID: PMC11231806, DOI: 10.1001/jamanetworkopen.2024.20702.
- Thompson R, Sabounchi N, Ali S, Heimer R, D’Onofrio G, Heckmann R. Using qualitative system dynamics modeling to understand overdose bystander behavior in the context of Connecticut’s Good Samaritan Laws and identify effective policy options. Harm Reduction Journal 2024, 21: 124. PMID: 38937759, PMCID: PMC11210010, DOI: 10.1186/s12954-024-00990-3.
- Savitz S, Stevens M, Nath B, D’Onofrio G, Melnick E, Jeffery M. Trends in the Prescribing of Buprenorphine for Opioid Use Disorder, 2019-2023. Mayo Clinic Proceedings Innovations Quality & Outcomes 2024, 8: 308-320. PMID: 38841599, PMCID: PMC11152959, DOI: 10.1016/j.mayocpiqo.2024.04.004.
- Kazemitabar M, Howell B, Becker W, Lin H, Grau L, Heimer R, D'Onofrio G, Hawk K, Fiellin D, Black A. Prescription Opioid Dose Change Prior to Fatal Opioid-Detected Overdose. Journal Of Studies On Alcohol And Drugs 2024 PMID: 38775307, DOI: 10.15288/jsad.24-00026.
- Zhu C, Dreyer R, Li F, Spatz E, Caraballo C, Mahajan S, Raparelli V, Leifheit E, Lu Y, Krumholz H, Spertus J, D'Onofrio G, Pilote L, Lichtman J. Association of marital/partner status with hospital readmission among young adults with acute myocardial infarction. PLOS ONE 2024, 19: e0287949. PMID: 38277368, PMCID: PMC10817183, DOI: 10.1371/journal.pone.0287949.
- Safdar B, Sobiesk M, Bertsimas D, Nowroozpoor A, Deng Y, D’Onofrio G, Dziura J, El-Khoury J, Guo X, Simonov M, Taylor R, Wang M, Desir G. Renalase Identified by Machine Learning Methods as A Novel Independent Predictor of Mortality in Hospitalized Patients with COVID-19. Journal Of Biotechnology And Biomedicine 2024, 07 DOI: 10.26502/jbb.2642-91280139.
- Heimer R, Black A, Lin H, Grau L, Fiellin D, Howell B, Hawk K, D'Onofrio G, Becker W. Receipt of opioid use disorder treatments prior to fatal overdoses and comparison to no treatment in Connecticut, 2016–17. Drug And Alcohol Dependence 2023, 254: 111040. PMID: 38043226, PMCID: PMC10872282, DOI: 10.1016/j.drugalcdep.2023.111040.
- Hawk K, Weiner S, Rothenberg C, Bernstein E, D'Onofrio G, Herring A, Hoppe J, Ketcham E, LaPietra A, Nelson L, Perrone J, Ranney M, Samuels E, Strayer R, Sharma D, Goyal P, Schuur J, Venkatesh A. Leveraging a Learning Collaborative Model to Develop and Pilot Quality Measures to Improve Opioid Prescribing in the Emergency Department. Annals Of Emergency Medicine 2023, 83: 225-234. PMID: 37831040, DOI: 10.1016/j.annemergmed.2023.08.490.
- Taylor R, Gilson A, Schulz W, Lopez K, Young P, Pandya S, Coppi A, Chartash D, Fiellin D, D’Onofrio G. Computational phenotypes for patients with opioid-related disorders presenting to the emergency department. PLOS ONE 2023, 18: e0291572. PMID: 37713393, PMCID: PMC10503758, DOI: 10.1371/journal.pone.0291572.
- D'Onofrio G, Perrone J, Hawk K, Cowan E, McCormack R, Coupet E, Owens P, Martel S, Huntley K, Walsh S, Lofwall M, Herring A, Investigators T. Early emergency department experience with 7‐day extended‐release injectable buprenorphine for opioid use disorder. Academic Emergency Medicine 2023, 30: 1264-1271. PMID: 37501652, PMCID: PMC10822018, DOI: 10.1111/acem.14782.
- Zhu C, Dreyer R, Li F, Spatz E, Caraballo‐Cordovez C, Mahajan S, Raparelli V, Leifheit E, Lu Y, Krumholz H, Spertus J, D'Onofrio G, Pilote L, Lichtman J. Impact of Marital Stress on 1‐Year Health Outcomes Among Young Adults With Acute Myocardial Infarction. Journal Of The American Heart Association 2023, 12: e030031. PMID: 37589125, PMCID: PMC10547344, DOI: 10.1161/jaha.123.030031.
- Yang D, Panthagani K, Ryus C, Nelson A, Wright D, Sherak R, Bernstein S, D'Onofrio G. Yale Emergency Scholars (YES) Program: A model for expanding emergency medicine research capacity. Academic Emergency Medicine 2023, 30: 1179-1182. PMID: 37436420, DOI: 10.1111/acem.14777.
- Jeffery M, Stevens M, D'Onofrio G, Melnick E. Fentanyl-Associated Overdose Deaths Outside the Hospital. New England Journal Of Medicine 2023, 389: 87-88. PMID: 37342960, PMCID: PMC10388669, DOI: 10.1056/nejmc2304991.
- Cowan E, Perrone J, Dziura J, Edelman E, Hawk K, Herring A, McCormack R, Murphy A, Phadke M, Fiellin D, D'Onofrio G. URINE TOXICOLOGY PROFILES OF EMERGENCY DEPARTMENT PATIENTS WITH UNTREATED OPIOID USE DISORDER: A MULTI-SITE VIEW. Journal Of Emergency Medicine 2023, 65: e357-e365. PMID: 37716904, PMCID: PMC10591927, DOI: 10.1016/j.jemermed.2023.06.007.
- Cowan E, Perrone J, Bernstein S, Coupet E, Fiellin D, Hawk K, Herring A, Huntley K, McCormack R, Venkatesh A, D'Onofrio G. National Institute on Drug Abuse Clinical Trials Network Meeting Report: Advancing Emergency Department Initiation of Buprenorphine for Opioid Use Disorder. Annals Of Emergency Medicine 2023, 82: 326-335. PMID: 37178101, PMCID: PMC10524880, DOI: 10.1016/j.annemergmed.2023.03.025.
- Justen M, Edelman E, Chawarski M, Coupet E, Cowan E, Lyons M, Owens P, Martel S, Richardson L, Rothman R, Whiteside L, O'Connor P, Zahn E, D'Onofrio G, Fiellin D, Hawk K. Perspectives on and experiences of emergency department–initiated buprenorphine among clinical pharmacists: A multi-site qualitative study. Journal Of Substance Use And Addiction Treatment 2023, 155: 209058. PMID: 37149149, DOI: 10.1016/j.josat.2023.209058.
- McCormack R, Rotrosen J, Gauthier P, D'Onofrio G, Fiellin D, Marsch L, Novo P, Liu D, Edelman E, Farkas S, Matthews A, Mulatya C, Salazar D, Wolff J, Knight R, Goodman W, Williams J, Hawk K. Implementing Programs to Initiate Buprenorphine for Opioid Use Disorder Treatment in High-Need, Low-Resource Emergency Departments: A Nonrandomized Controlled Trial. Annals Of Emergency Medicine 2023, 82: 272-287. PMID: 37140493, PMCID: PMC10524047, DOI: 10.1016/j.annemergmed.2023.02.013.
- Sawano M, Lu Y, Caraballo C, Mahajan S, Dreyer R, Lichtman J, D'Onofrio G, Spatz E, Khera R, Onuma O, Murugiah K, Spertus J, Krumholz H. Sex Difference in Outcomes of Acute Myocardial Infarction in Young Patients. Journal Of The American College Of Cardiology 2023, 81: 1797-1806. PMID: 37137590, DOI: 10.1016/j.jacc.2023.03.383.
- Sue K, Chawarski M, Curry L, McNeil R, Coupet E, Schwartz R, Wilder C, Tsui J, Hawk K, D’Onofrio G, O’Connor P, Fiellin D, Edelman E. Perspectives of Clinicians and Staff at Community-Based Opioid Use Disorder Treatment Settings on Linkages With Emergency Department–Initiated Buprenorphine Programs. JAMA Network Open 2023, 6: e2312718. PMID: 37163263, PMCID: PMC10173026, DOI: 10.1001/jamanetworkopen.2023.12718.
- Vaca F, Dziura J, Abujarad F, Pantalon M, Hsiao A, Reynolds J, Maciejewski K, Field C, D’Onofrio G. Use of an Automated Bilingual Digital Health Tool to Reduce Unhealthy Alcohol Use Among Latino Emergency Department Patients. JAMA Network Open 2023, 6: e2314848. PMID: 37219901, PMCID: PMC10208138, DOI: 10.1001/jamanetworkopen.2023.14848.
- Brush J, Chaudhry S, Dreyer R, D'Onofrio G, Greene E, Hajduk A, Lu Y, Krumholz H. Sex Differences in Symptom Complexity and Door-to-Balloon Time in Patients With ST-Elevation Myocardial Infarction. The American Journal Of Cardiology 2023, 197: 101-107. PMID: 37062667, PMCID: PMC10198892, DOI: 10.1016/j.amjcard.2023.03.009.
- D’Onofrio G, Edelman E, Hawk K, Chawarski M, Pantalon M, Owens P, Martel S, Rothman R, Saheed M, Schwartz R, Cowan E, Richardson L, Salsitz E, Lyons M, Freiermuth C, Wilder C, Whiteside L, Tsui J, Klein J, Coupet E, O’Connor P, Matthews A, Murphy S, Huntley K, Fiellin D. Implementation Facilitation to Promote Emergency Department–Initiated Buprenorphine for Opioid Use Disorder. JAMA Network Open 2023, 6: e235439. PMID: 37017967, PMCID: PMC10077107, DOI: 10.1001/jamanetworkopen.2023.5439.
- Bernstein S, Li F, Abujarad F, Grant D, D'Onofrio G, Dziura J. Modeling human health behavior with a new index that measures connectivity. Preventive Medicine Reports 2023, 33: 102172. PMID: 37223571, PMCID: PMC10201843, DOI: 10.1016/j.pmedr.2023.102172.
- D’Onofrio G, Hawk K, Perrone J, Walsh S, Lofwall M, Fiellin D, Herring A. Incidence of Precipitated Withdrawal During a Multisite Emergency Department–Initiated Buprenorphine Clinical Trial in the Era of Fentanyl. JAMA Network Open 2023, 6: e236108. PMID: 36995717, PMCID: PMC10064247, DOI: 10.1001/jamanetworkopen.2023.6108.
- Holland W, Li F, Nath B, Jeffery M, Stevens M, Melnick E, Dziura J, Khidir H, Skains R, D'Onofrio G, Soares W. Racial and ethnic disparities in emergency department–initiated buprenorphine across five health care systems. Academic Emergency Medicine 2023, 30: 709-720. PMID: 36660800, PMCID: PMC10467357, DOI: 10.1111/acem.14668.
- Hawk K, D'Onofrio G. Time to Treat Alcohol Use Disorder in the Emergency Department. Annals Of Emergency Medicine 2023, 81: 450-452. PMID: 36775724, DOI: 10.1016/j.annemergmed.2022.11.013.
- Sangal R, Rothenberg C, Hawk K, D'Onofrio G, Hsiao A, Solad Y, Venkatesh A. Real-World Observational Evaluation of Common Interventions to Reduce Emergency Department Prescribing of Opioid Medications. The Joint Commission Journal On Quality And Patient Safety 2023, 49: 239-246. PMID: 36914528, DOI: 10.1016/j.jcjq.2023.01.013.
- Okafor C, Zhu C, Raparelli V, Murphy T, Arakaki A, D’Onofrio G, Tsang S, Smith M, Lichtman J, Spertus J, Pilote L, Dreyer R. Association of Sociodemographic Characteristics With 1-Year Hospital Readmission Among Adults Aged 18 to 55 Years With Acute Myocardial Infarction. JAMA Network Open 2023, 6: e2255843. PMID: 36787140, PMCID: PMC9929697, DOI: 10.1001/jamanetworkopen.2022.55843.
- Howell B, Black A, Grau L, Lin H, Greene C, Lee H, Heimer R, Hawk K, D'Onofrio G, Fiellin D, Becker W. Concordance between controlled substance receipt and post-mortem toxicology in opioid-detected overdose deaths: A statewide analysis. Drug And Alcohol Dependence 2023, 244: 109788. PMID: 36738634, PMCID: PMC9975083, DOI: 10.1016/j.drugalcdep.2023.109788.
- Abujarad F, Choo E, Dziura J, Edwards C, Pantalon M, Jubanyik K, D'Onofrio G, Gill T. A DIGITAL ELDER ABUSE INTERVENTION FOR THE EMERGENCY DEPARTMENT. Innovation In Aging 2022, 6: 425-425. PMCID: PMC9766766, DOI: 10.1093/geroni/igac059.1669.
- Dreyer R, Arakaki A, Raparelli V, Murphy T, Tsang S, D’Onofrio G, Wood M, Wright C, Pilote L. Young Women With Acute Myocardial Infarction: Risk Prediction Model for 1-Year Hospital Readmission. CJC Open 2022, 5: 335-344. PMID: 37377522, PMCID: PMC10290947, DOI: 10.1016/j.cjco.2022.12.004.
- Taylor A, Kinsman J, Hawk K, D'Onofrio G, Malicki C, Malcom B, Goyal P, Venkatesh A. Development and testing of data infrastructure in the American College of Emergency Physicians’ Clinical Emergency Data Registry for opioid‐related research. Journal Of The American College Of Emergency Physicians Open 2022, 3: e12816. PMID: 36311336, PMCID: PMC9597093, DOI: 10.1002/emp2.12816.
- Ali S, Sabounchi N, Thompson R, Heimer R, D’Onofrio G, Heckmann R. 168 Impact of Connecticut’s Good Samaritan Laws in Preventing Opioid Overdose Deaths – An Applied System Dynamics Approach. Annals Of Emergency Medicine 2022, 80: s76-s77. DOI: 10.1016/j.annemergmed.2022.08.192.
- Lyons MS, Chawarski MC, Rothman R, Whiteside L, Cowan E, Richardson LD, Hawk K, Tsui JI, Schwartz RP, O’Connor P, D’Onofrio G, Fiellin DA, Edelman EJ. Missed Opportunities for HIV and Hepatitis C Screening Among Emergency Department Patients With Untreated Opioid Use Disorder. Journal Of Addiction Medicine 2022, 17: 210-214. PMID: 36170184, PMCID: PMC10023471, DOI: 10.1097/adm.0000000000001074.
- Kaur A, Dreyer R, Marsh T, Thanassoulis G, Raparelli V, D’Onofrio G, Engert J, Pilote L. Sex Differences in Clopidogrel Effects Among Young Patients With Acute Coronary Syndrome: A Role for Genetics? CJC Open 2022, 4: 970-978. PMID: 36444366, PMCID: PMC9700217, DOI: 10.1016/j.cjco.2022.07.013.
- Melnick ER, Nath B, Dziura JD, Casey MF, Jeffery MM, Paek H, Soares WE, Hoppe JA, Rajeevan H, Li F, Skains RM, Walter LA, Patel MD, Chari SV, Platts-Mills TF, Hess EP, D'Onofrio G. User centered clinical decision support to implement initiation of buprenorphine for opioid use disorder in the emergency department: EMBED pragmatic cluster randomized controlled trial. The BMJ 2022, 377: e069271. PMID: 35760423, PMCID: PMC9231533, DOI: 10.1136/bmj-2021-069271.
- Whiteside LK, D'Onofrio G, Fiellin DA, Edelman EJ, Richardson L, O'Connor P, Rothman RE, Cowan E, Lyons MS, Fockele CE, Saheed M, Freiermuth C, Punches BE, Guo C, Martel S, Owens PH, Coupet E, Hawk KF. Models for Implementing Emergency Department–Initiated Buprenorphine With Referral for Ongoing Medication Treatment at Emergency Department Discharge in Diverse Academic Centers. Annals Of Emergency Medicine 2022, 80: 410-419. PMID: 35752520, PMCID: PMC9588652, DOI: 10.1016/j.annemergmed.2022.05.010.
- Stevens MA, Tsai J, Savitz ST, Nath B, Melnick ER, D’Onofrio G, Jeffery MM. Trends and Disparities in Access to Buprenorphine Treatment Following an Opioid-Related Emergency Department Visit Among an Insured Cohort, 2014-2020. JAMA Network Open 2022, 5: e2215287. PMID: 35657629, PMCID: PMC9166266, DOI: 10.1001/jamanetworkopen.2022.15287.
- Safdar B, Mori M, Nowroozpoor A, Geirsson A, D'Onofrio G, Mangi AA. Clinical Profile and Sex-Specific Recovery With Cardiac Rehabilitation After Coronary Artery Bypass Grafting Surgery. Clinical Therapeutics 2022, 44: 846-858. PMID: 35570056, DOI: 10.1016/j.clinthera.2022.04.002.
- Lu Y, Li SX, Liu Y, Rodriguez F, Watson KE, Dreyer RP, Khera R, Murugiah K, D’Onofrio G, Spatz ES, Nasir K, Masoudi FA, Krumholz HM. Sex-Specific Risk Factors Associated With First Acute Myocardial Infarction in Young Adults. JAMA Network Open 2022, 5: e229953. PMID: 35503221, PMCID: PMC9066284, DOI: 10.1001/jamanetworkopen.2022.9953.
- Shenvi CL, Wang Y, Revankar R, Phillips J, Bush M, Biese KJ, Aylward A, D'Onofrio G, Platts‐Mills T. Use of a Brief Negotiation Interview in the emergency department to reduce high‐risk alcohol use among older adults: A randomized trial. Journal Of The American College Of Emergency Physicians Open 2022, 3: e12651. PMID: 35156089, PMCID: PMC8828696, DOI: 10.1002/emp2.12651.
- Rockett IRH, Jia H, Ali B, Banerjee A, Connery HS, Nolte KB, Miller T, White FMM, DiGregorio BD, Larkin GL, Stack S, Kõlves K, McHugh RK, Lulla VO, Cossman J, De Leo D, Hendricks B, Nestadt PS, Berry JH, D’Onofrio G, Caine ED. Association of State Social and Environmental Factors With Rates of Self-injury Mortality and Suicide in the United States. JAMA Network Open 2022, 5: e2146591. PMID: 35138401, PMCID: PMC8829661, DOI: 10.1001/jamanetworkopen.2021.46591.
- D'Onofrio G, Melnick ER, Hawk KF. In reply:. Annals Of Emergency Medicine 2022, 79: 219-220. PMID: 35065746, DOI: 10.1016/j.annemergmed.2021.10.022.
- Venkatesh AK, Janke AT, Kinsman J, Rothenberg C, Goyal P, Malicki C, D’Onofrio G, Taylor A, Hawk K. Emergency department utilization for substance use disorders and mental health conditions during COVID-19. PLOS ONE 2022, 17: e0262136. PMID: 35025921, PMCID: PMC8757912, DOI: 10.1371/journal.pone.0262136.
- Sabounchi NS, Heckmann R, D’Onofrio G, Walker J, Heimer R. Assessing the impact of the Good Samaritan Law in the state of Connecticut: a system dynamics approach. Health Research Policy And Systems 2022, 20: 5. PMID: 34991591, PMCID: PMC8734429, DOI: 10.1186/s12961-021-00807-w.
- Hawk K, McCormack R, Edelman EJ, Coupet E, Toledo N, Gauthier P, Rotrosen J, Chawarski M, Martel S, Owens P, Pantalon MV, O’Connor P, Whiteside LK, Cowan E, Richardson LD, Lyons MS, Rothman R, Marsch L, Fiellin DA, D’Onofrio G. Perspectives About Emergency Department Care Encounters Among Adults With Opioid Use Disorder. JAMA Network Open 2022, 5: e2144955. PMID: 35076700, PMCID: PMC8790663, DOI: 10.1001/jamanetworkopen.2021.44955.
- Taylor RA, Fiellin D, D'Onofrio G, Venkatesh A. Identifying Opioid-Related Electronic Health Record Phenotypes for Emergency Care Research and Surveillance: An Expert Consensus Driven Concept Mapping Process. Substance Abuse 2022, 43: 841-847. PMID: 35156912, DOI: 10.1080/08897077.2021.1975864.
- Abujarad F, Choo E, Dziura J, Edwards C, Pantalon M, Jubanyik K, D'Onofrio G, Gill T. Patient-Centered Digital Screener for Elder Abuse in the Emergency Department. Innovation In Aging 2021, 5: 152-152. PMCID: PMC8682507, DOI: 10.1093/geroni/igab046.580.
- Nowroozpoor A, Sharp E, Gordon R, Malicki C, Hwang U, Dziura J, D'Onofrio' G, Safdar B. Corrigendum to: Mild cognitive impairment in middle-aged adults with coronary microvascular dysfunction. European Heart Journal 2021, 43: 1776-1776. PMID: 34897369, DOI: 10.1093/eurheartj/ehab845.
- Guo CZ, D'Onofrio G, Fiellin DA, Edelman EJ, Hawk K, Herring A, McCormack R, Perrone J, Cowan E. Emergency department‐initiated buprenorphine protocols: A national evaluation. Journal Of The American College Of Emergency Physicians Open 2021, 2: e12606. PMID: 34877567, PMCID: PMC8630357, DOI: 10.1002/emp2.12606.
- Hawk K, Malicki C, Kinsman J, D’Onofrio G, Taylor A, Venkatesh A. Feasibility and acceptability of electronic administration of patient reported outcomes using mHealth platform in emergency department patients with non-medical opioid use. Addiction Science & Clinical Practice 2021, 16: 66. PMID: 34758881, PMCID: PMC8579535, DOI: 10.1186/s13722-021-00276-0.
- Nowroozpoor A, Sharp E, Gordon R, Malicki C, Hwang U, Dziura J, D'Onofrio' G, Safdar B. Mild cognitive impairment in middle-aged adults with coronary microvascular dysfunction. European Heart Journal 2021, 42: ehab724.2744. DOI: 10.1093/eurheartj/ehab724.2744.
- Raparelli V, Pilote L, Dang B, Behlouli H, Dziura JD, Bueno H, D’Onofrio G, Krumholz HM, Dreyer RP. Variations in Quality of Care by Sex and Social Determinants of Health Among Younger Adults With Acute Myocardial Infarction in the US and Canada. JAMA Network Open 2021, 4: e2128182. PMID: 34668947, PMCID: PMC8529414, DOI: 10.1001/jamanetworkopen.2021.28182.
- Scofi J, Parwani V, Rothenberg C, Patel A, Ravi S, Sevilla M, D'Onofrio G, Ulrich A, Venkatesh AK. Improving Emergency Department Throughput Using Audit-and-Feedback With Peer Comparison Among Emergency Department Physicians. Journal For Healthcare Quality 2021, 44: 69-77. PMID: 34570029, DOI: 10.1097/jhq.0000000000000329.
- Neumar RW, Blomkalns AL, Cairns CB, D’Onofrio G, Kuppermann N, Lewis RJ, Newgard CD, O’Neil B, Rathlev NK, Rothman RE, Wright DW. Emergency medicine research: 2030 strategic goals. Academic Emergency Medicine 2021, 29: 241-251. PMID: 34363718, DOI: 10.1111/acem.14367.
- Samuels E, Coupet E, D’Onofrio G. Emergency Department Treatment of Opioid Use Disorder. 2021, 57-75. DOI: 10.1007/978-3-030-80818-1_5.
- Dreyer RP, Raparelli V, Tsang SW, D’Onofrio G, Lorenze N, Xie CF, Geda M, Pilote L, Murphy TE. Development and Validation of a Risk Prediction Model for 1‐Year Readmission Among Young Adults Hospitalized for Acute Myocardial Infarction. Journal Of The American Heart Association 2021, 10: e021047. PMID: 34514837, PMCID: PMC8649501, DOI: 10.1161/jaha.121.021047.
- Raparelli V, Benea D, Smith M, Behlouli H, Murphy TE, D’Onofrio G, Pilote L, Dreyer RP. Impact of Race on the In‐Hospital Quality of Care Among Young Adults With Acute Myocardial Infarction. Journal Of The American Heart Association 2021, 10: e021408. PMID: 34431311, PMCID: PMC8649291, DOI: 10.1161/jaha.121.021408.
- Anderson ES, Chamberlin M, Zuluaga M, Ullal M, Hawk K, McCormack R, D'Onofrio G, Herring AA. Implementation of Oral and Extended-Release Naltrexone for the Treatment of Emergency Department Patients With Moderate to Severe Alcohol Use Disorder: Feasibility and Initial Outcomes. Annals Of Emergency Medicine 2021, 78: 752-758. PMID: 34353648, DOI: 10.1016/j.annemergmed.2021.05.013.
- Gaeta M, Nowroozpoor A, Dziura J, D'Onofrio G, Sinusas AJ, Safdar B. Use of peripheral arterial tonometry in detection of abnormal coronary flow reserve. Microvascular Research 2021, 138: 104223. PMID: 34256085, PMCID: PMC10227886, DOI: 10.1016/j.mvr.2021.104223.
- Herring AA, Vosooghi AA, Luftig J, Anderson ES, Zhao X, Dziura J, Hawk KF, McCormack RP, Saxon A, D’Onofrio G. High-Dose Buprenorphine Induction in the Emergency Department for Treatment of Opioid Use Disorder. JAMA Network Open 2021, 4: e2117128. PMID: 34264326, PMCID: PMC8283555, DOI: 10.1001/jamanetworkopen.2021.17128.
- Tuzzio L, Meyers CM, Dember LM, Grudzen CR, Melnick ER, Staman KL, Huang SS, Richards J, DeBar L, Vazquez MA, Green BB, Coronado GD, Jarvik JG, Braciszewski J, Ho PM, Wells BL, James K, Toto R, D’Onofrio G, Volandes A, Kuklinski MR, Catalano RF, Sterling SA, Morse EF, Curtis L, Larson EB. Accounting for quality improvement during the conduct of embedded pragmatic clinical trials within healthcare systems: NIH Collaboratory case studies. Healthcare 2021, 8: 100432. PMID: 34175091, PMCID: PMC8900087, DOI: 10.1016/j.hjdsi.2020.100432.
- Hawk K, Hoppe J, Ketcham E, LaPietra A, Moulin A, Nelson L, Schwarz E, Shahid S, Stader D, Wilson MP, D'Onofrio G. Consensus Recommendations on the Treatment of Opioid Use Disorder in the Emergency Department. Annals Of Emergency Medicine 2021, 78: 434-442. PMID: 34172303, DOI: 10.1016/j.annemergmed.2021.04.023.
- Gilson AS, Chartash D, Chang D, Hawk K, D'Onofrio G, Haimovich AD, Fiellin DA, Taylor RA. Analysis of Health Trajectories Leading to Adverse Opioid-Related Events. AMIA Joint Summits On Translational Science Proceedings 2021, 2021: 248-256. PMID: 34457139, PMCID: PMC8378649.
- D'Onofrio G, Melnick ER, Hawk KF. Improve Access to Care for Opioid Use Disorder: A Call to Eliminate the X-Waiver Requirement Now. Annals Of Emergency Medicine 2021, 78: 220-222. PMID: 33966933, PMCID: PMC8324519, DOI: 10.1016/j.annemergmed.2021.03.023.
- Kaur A, Dreyer R, Marsh T, Thanassoulis G, Raparelli V, D'Onofrio G, Engert J, Pilote L. ROLE OF GENETICS IN SEX-SPECIFIC EFFECTS OF CLOPIDOGREL ON ATHEROTHROMBOTIC EVENTS. Journal Of The American College Of Cardiology 2021, 77: 181. DOI: 10.1016/s0735-1097(21)01540-0.
- Pantalon MV, Dziura J, Li FY, D'Onofrio G, Weiss J, Bernstein SL. A Brief Negotiation Interview Adherence Scale for Smoking Cessation: A psychometric evaluation. Journal Of Substance Use And Addiction Treatment 2021, 126: 108398. PMID: 34116807, DOI: 10.1016/j.jsat.2021.108398.
- Gettel CJ, Canavan ME, D'Onofrio G, Carr BG, Venkatesh AK. Corrigendum to “Who provides what care? An analysis of clinical focus among the national emergency care workforce” [Am J Emerg Med. 2021 Apr;42:228–232]. The American Journal Of Emergency Medicine 2021, 46: 804. PMID: 33875317, PMCID: PMC8338896, DOI: 10.1016/j.ajem.2021.04.015.
- Soares WE, Melnick ER, Nath B, D'Onofrio G, Paek H, Skains RM, Walter LA, Casey MF, Napoli A, Hoppe JA, Jeffery MM. Emergency Department Visits for Nonfatal Opioid Overdose During the COVID-19 Pandemic Across Six US Health Care Systems. Annals Of Emergency Medicine 2021, 79: 158-167. PMID: 34119326, PMCID: PMC8449788, DOI: 10.1016/j.annemergmed.2021.03.013.
- D'Onofrio G, Hawk KF, Herring AA, Perrone J, Cowan E, McCormack RP, Dziura J, Taylor RA, Coupet E, Edelman EJ, Pantalon MV, Owens PH, Martel SH, O'Connor PG, Van Veldhuisen P, DeVogel N, Huntley K, Murphy SM, Lofwall MR, Walsh SL, Fiellin DA. The design and conduct of a randomized clinical trial comparing emergency department initiation of sublingual versus a 7-day extended-release injection formulation of buprenorphine for opioid use disorder: Project ED Innovation. Contemporary Clinical Trials 2021, 104: 106359. PMID: 33737199, PMCID: PMC9153252, DOI: 10.1016/j.cct.2021.106359.
- McCormack RP, Rotrosen J, Gauthier P, D’Onofrio G, Fiellin DA, Marsch LA, Novo P, Liu D, Edelman EJ, Farkas S, Matthews AG, Mulatya C, Salazar D, Wolff J, Knight R, Goodman W, Hawk K. Implementation facilitation to introduce and support emergency department-initiated buprenorphine for opioid use disorder in high need, low resource settings: protocol for multi-site implementation-feasibility study. Addiction Science & Clinical Practice 2021, 16: 16. PMID: 33750454, PMCID: PMC7941881, DOI: 10.1186/s13722-021-00224-y.
- Samuels EA, Kelley L, Pham T, Cross J, Carmona J, Ellis P, Cobbs-Lomax D, D’Onofrio G, Capp R. “I wanted to participate in my own care”: Evaluation of a Patient Navigation Program. Western Journal Of Emergency Medicine 2021, 22: 417-426. PMID: 33856334, PMCID: PMC7972383, DOI: 10.5811/westjem.2020.9.48105.
- Hawk K, Grau LE, Fiellin DA, Chawarski M, O’Connor P, Cirillo N, Breen C, D’Onofrio G. A qualitative study of emergency department patients who survived an opioid overdose: Perspectives on treatment and unmet needs. Academic Emergency Medicine 2021, 28: 542-552. PMID: 33346926, PMCID: PMC8281441, DOI: 10.1111/acem.14197.
- Rockett IRH, Caine ED, Banerjee A, Ali B, Miller T, Connery HS, Lulla VO, Nolte KB, Larkin GL, Stack S, Hendricks B, McHugh RK, White FMM, Greenfield SF, Bohnert ASB, Cossman JS, D'Onofrio G, Nelson LS, Nestadt PS, Berry JH, Jia H. Fatal self-injury in the United States, 1999–2018: Unmasking a national mental health crisis. EClinicalMedicine 2021, 32: 100741. PMID: 33681743, PMCID: PMC7910714, DOI: 10.1016/j.eclinm.2021.100741.
- Becker WC, Heimer R, Dormitzer CM, Doernberg M, D’Onofrio G, Grau LE, Hawk K, Lin HJ, Secora AM, Fiellin DA. Merging statewide data in a public/university collaboration to address opioid use disorder and overdose. Addiction Science & Clinical Practice 2021, 16: 1. PMID: 33397480, PMCID: PMC7780404, DOI: 10.1186/s13722-020-00211-9.
- Abujarad F, Choo E, Pantalon M, Jubanyik K, Dziura J, Edwards C, D’Onofrio G, Gill T. Digital Health Tool to Assist Older Adults in Self-Disclosing Elder Mistreatment. Innovation In Aging 2020, 4: 755-756. PMCID: PMC7743726, DOI: 10.1093/geroni/igaa057.2724.
- Perceived Value of Using a Digital Tool to Screen for Elder Mistreatment in the Emergency DepartmentAbujarad F, Gill T, Pantalon M, Jubanyik K, Dziura J, D’Onofrio G, Choo E. Perceived Value of Using a Digital Tool to Screen for Elder Mistreatment in the Emergency Department. Innovation In Aging 2020, 4: 195-195. PMCID: PMC7740753, DOI: 10.1093/geroni/igaa057.631.
- Coupet E, D’Onofrio G, Chawarski M, Edelman E, O’Connor P, Owens P, Martel S, Fiellin DA, Cowan E, Richardson L, Huntley K, Whiteside LK, Lyons MS, Rothman RE, Pantalon M, Hawk K. Emergency department patients with untreated opioid use disorder: A comparison of those seeking versus not seeking referral to substance use treatment. Drug And Alcohol Dependence 2020, 219: 108428. PMID: 33307301, PMCID: PMC8110210, DOI: 10.1016/j.drugalcdep.2020.108428.
- Raparelli V, Pilote L, Behlouli H, Dziura J, Bueno H, D'Onofrio G, Krumholz H, Dreyer R. The impact of sex, gender and healthcare system on quality of care among young adults with acute myocardial infarction. European Heart Journal 2020, 41: ehaa946.3175. DOI: 10.1093/ehjci/ehaa946.3175.
- Cone DC, Bogucki S, Burns K, D’Onofrio G, Hawk K, Joseph D, Fiellin DA. Naloxone Use by Emergency Medical Services During the COVID-19 Pandemic: A National Survey. Journal Of Addiction Medicine 2020, 14: e369-e371. PMID: 33031212, PMCID: PMC7647432, DOI: 10.1097/adm.0000000000000746.
- Abujarad F, Edwards C, Choo E, Pantalon M, Jubanyik K, Dziura J, D'Onofrio G, Gill T. Digital health screening tool for identification of elder mistreatment. Gerontechnology 2020, 19: 1-1. PMID: 33574738, PMCID: PMC7875481, DOI: 10.4017/gt.2020.19.s.70138.
- Rhee TG, D’Onofrio G, Fiellin DA. Trends in the Use of Buprenorphine in US Emergency Departments, 2002-2017. JAMA Network Open 2020, 3: e2021209. PMID: 33079195, PMCID: PMC7576404, DOI: 10.1001/jamanetworkopen.2020.21209.
- Jubanyik K, Choo E, Pantalon M, Dziura J, Edwards C, Gill T, D'Onofrio G, Abujarad F. 404 Emergency Department Tablet-Based Screening Tool for Elder Abuse. Annals Of Emergency Medicine 2020, 76: s154. DOI: 10.1016/j.annemergmed.2020.09.420.
- Jeffery MM, D’Onofrio G, Paek H, Platts-Mills TF, Soares WE, Hoppe JA, Genes N, Nath B, Melnick ER. Trends in Emergency Department Visits and Hospital Admissions in Health Care Systems in 5 States in the First Months of the COVID-19 Pandemic in the US. JAMA Internal Medicine 2020, 180: 1328-1333. PMID: 32744612, PMCID: PMC7400214, DOI: 10.1001/jamainternmed.2020.3288.
- Venkatesh AK, Gettel CJ, Mei H, Chou SC, Rothenberg C, Liu SL, D’Onofrio G, Lin Z, Krumholz HM. Where Skilled Nursing Facility Residents Get Acute Care: Is the Emergency Department the Medical Home? Journal Of Applied Gerontology 2020, 40: 828-836. PMID: 32842827, PMCID: PMC7904961, DOI: 10.1177/0733464820950125.
- Venkatesh A, Malicki C, Hawk K, D’Onofrio G, Kinsman J, Taylor A. Assessing the readiness of digital data infrastructure for opioid use disorder research. Addiction Science & Clinical Practice 2020, 15: 24. PMID: 32650817, PMCID: PMC7350566, DOI: 10.1186/s13722-020-00198-3.
- Venkatesh AK, Mei H, Shuling L, D’Onofrio G, Rothenberg C, Lin Z, Krumholz HM. Cross‐sectional Analysis of Emergency Department and Acute Care Utilization Among Medicare Beneficiaries. Academic Emergency Medicine 2020, 27: 570-579. PMID: 32302034, DOI: 10.1111/acem.13971.
- Hawk KF, D’Onofrio G, Chawarski MC, O’Connor P, Cowan E, Lyons MS, Richardson L, Rothman RE, Whiteside LK, Owens PH, Martel SH, Coupet E, Pantalon M, Curry L, Fiellin DA, Edelman EJ. Barriers and Facilitators to Clinician Readiness to Provide Emergency Department–Initiated Buprenorphine. JAMA Network Open 2020, 3: e204561. PMID: 32391893, PMCID: PMC7215257, DOI: 10.1001/jamanetworkopen.2020.4561.
- Melnick ER, Nath B, Ahmed OM, Brandt C, Chartash D, Dziura JD, Hess EP, Holland WC, Hoppe JA, Jeffery MM, Katsovich L, Li F, Lu CC, Maciejewski K, Maleska M, Mao JA, Martel S, Michael S, Paek H, Patel MD, Platts-Mills TF, Rajeevan H, Ray JM, Skains RM, Soares WE, Deutsch A, Solad Y, D’Onofrio G. Progress Report on EMBED: A Pragmatic Trial of User-Centered Clinical Decision Support to Implement EMergency Department-Initiated BuprenorphinE for Opioid Use Disorder †. Journal Of Psychiatry And Brain Science 2020, 2: e200003. PMID: 32309637, PMCID: PMC7164817, DOI: 10.20900/jpbs.20200003.
- Melnick ER, Holland WC, Ahmed OM, K A, Michael SS, Goldberg HS, Lagier C, D’Onofrio G, Stachowiak T, Brandt C, Solad Y. An integrated web application for decision support and automation of EHR workflow: a case study of current challenges to standards-based messaging and scalability from the EMBED trial. JAMIA Open 2019, 2: 434-439. PMID: 32025639, PMCID: PMC6994013, DOI: 10.1093/jamiaopen/ooz053.
- Hawk K, D’Onofrio G. Correction to: Emergency department screening and interventions for substance use disorders. Addiction Science & Clinical Practice 2019, 14: 26. PMID: 31311584, PMCID: PMC6636051, DOI: 10.1186/s13722-019-0155-3.
- Melnick ER, Jeffery MM, Dziura JD, Mao JA, Hess EP, Platts-Mills TF, Solad Y, Paek H, Martel S, Patel MD, Bankowski L, Lu C, Brandt C, D’Onofrio G. User-centred clinical decision support to implement emergency department-initiated buprenorphine for opioid use disorder: protocol for the pragmatic group randomised EMBED trial. BMJ Open 2019, 9: e028488. PMID: 31152039, PMCID: PMC6550013, DOI: 10.1136/bmjopen-2018-028488.
- D’Onofrio G, Edelman EJ, Hawk KF, Pantalon MV, Chawarski MC, Owens PH, Martel SH, VanVeldhuisen P, Oden N, Murphy SM, Huntley K, O’Connor P, Fiellin DA. Implementation facilitation to promote emergency department-initiated buprenorphine for opioid use disorder: protocol for a hybrid type III effectiveness-implementation study (Project ED HEALTH). Implementation Science 2019, 14: 48. PMID: 31064390, PMCID: PMC6505286, DOI: 10.1186/s13012-019-0891-5.
- Association Between Insurance Status and Access to Hospital Care in Emergency Department DispositionVenkatesh AK, Chou SC, Li SX, Choi J, Ross JS, D’Onofrio G, Krumholz HM, Dharmarajan K. Association Between Insurance Status and Access to Hospital Care in Emergency Department Disposition. JAMA Internal Medicine 2019, 179: 686-693. PMID: 30933243, PMCID: PMC6503571, DOI: 10.1001/jamainternmed.2019.0037.
- Ray JM, Ahmed OM, Solad Y, Maleska M, Martel S, Jeffery MM, Platts-Mills TF, Hess EP, D’Onofrio G, Melnick ER. Computerized Clinical Decision Support System for Emergency Department–Initiated Buprenorphine for Opioid Use Disorder: User-Centered Design. JMIR Human Factors 2019, 6: e13121. PMID: 30810531, PMCID: PMC6414819, DOI: 10.2196/13121.
- Samuels EA, D'Onofrio G, Huntley K, Levin S, Schuur JD, Bart G, Hawk K, Tai B, Campbell CI, Venkatesh AK. A Quality Framework for Emergency Department Treatment of Opioid Use Disorder. Annals Of Emergency Medicine 2018, 73: 237-247. PMID: 30318376, PMCID: PMC6817947, DOI: 10.1016/j.annemergmed.2018.08.439.
- Zogg C, Rook J, Schlesinger M, Schwartz J, Henschen B, Winkelman T, Haider A, D'Onofrio G. 2EMF Understanding Emergency Medicine Providers’ Perceptions of the ACA in a Renewed Era of Health Care Reform: National Survey and Qualitative Mixed-Methods Approach. Annals Of Emergency Medicine 2018, 72: s154. DOI: 10.1016/j.annemergmed.2018.08.399.
- Zogg C, Rook J, Das B, Schlesinger M, Schwartz J, Haider A, D’Onofrio G. 301 United States Emergency Medicine Providers' Perceptions of Health Care Disparities: A National Survey. Annals Of Emergency Medicine 2018, 72: s118-s119. DOI: 10.1016/j.annemergmed.2018.08.306.
- Hawk K, D’Onofrio G. Emergency department screening and interventions for substance use disorders. Addiction Science & Clinical Practice 2018, 13: 18. PMID: 30078375, PMCID: PMC6077851, DOI: 10.1186/s13722-018-0117-1.
- Safdar B, Spatz ES, Dreyer RP, Beltrame JF, Lichtman JH, Spertus JA, Reynolds HR, Geda M, Bueno H, Dziura JD, Krumholz HM, D'Onofrio G. Presentation, Clinical Profile, and Prognosis of Young Patients With Myocardial Infarction With Nonobstructive Coronary Arteries (MINOCA): Results From the VIRGO Study. Journal Of The American Heart Association 2018, 7: e009174. PMID: 29954744, PMCID: PMC6064896, DOI: 10.1161/jaha.118.009174.
- Safdar B, D’Onofrio G, Dziura J, Russell RR, Johnson C, Sinusas AJ. Prevalence and characteristics of coronary microvascular dysfunction among chest pain patients in the emergency department. European Heart Journal Acute Cardiovascular Care 2018, 9: 5-13. PMID: 29543037, DOI: 10.1177/2048872618764418.
- Lichtman JH, Leifheit EC, Safdar B, Bao H, Krumholz HM, Lorenze NP, Daneshvar M, Spertus JA, D'Onofrio G. Sex Differences in the Presentation and Perception of Symptoms Among Young Patients With Myocardial Infarction. Circulation 2018, 137: 781-790. PMID: 29459463, PMCID: PMC5822747, DOI: 10.1161/circulationaha.117.031650.
- Rockett IRH, Caine ED, Connery HS, D’Onofrio G, Gunnell DJ, Miller TR, Nolte KB, Kaplan MS, Kapusta ND, Lilly CL, Nelson LS, Putnam SL, Stack S, Värnik P, Webster LR, Jia H. Discerning suicide in drug intoxication deaths: Paucity and primacy of suicide notes and psychiatric history. PLOS ONE 2018, 13: e0190200. PMID: 29320540, PMCID: PMC5761891, DOI: 10.1371/journal.pone.0190200.
- Kim Y, Hogan K, D’Onofrio G, Chekijian S, Safdar B. Patient Ethnicity Predicts Poor Health Access and Gaps in Perception of Personal Cardiovascular Risk Factors. Critical Pathways In Cardiology A Journal Of Evidence-Based Medicine 2017, 16: 147-157. PMID: 29135623, DOI: 10.1097/hpc.0000000000000132.
- Busch SH, Fiellin DA, Chawarski MC, Owens PH, Pantalon MV, Hawk K, Bernstein SL, O'Connor PG, D'Onofrio G. Cost‐effectiveness of emergency department‐initiated treatment for opioid dependence. Addiction 2017, 112: 2002-2010. PMID: 28815789, PMCID: PMC5657503, DOI: 10.1111/add.13900.
- Bernstein SL, D’Onofrio G. Screening, treatment initiation, and referral for substance use disorders. Addiction Science & Clinical Practice 2017, 12: 18. PMID: 28780906, PMCID: PMC5545867, DOI: 10.1186/s13722-017-0083-z.
- Lindau S, Abramsohn E, Bueno H, D’Onofrio G, Lichtman J, Lorenze N, Sanghani R, Spatz E, Spertus J, Strait K, Wroblewski K, Zhou S, Krumholz H. Sexual Activity and Function in the Year After an Acute Myocardial Infarction Among Younger Women and Men in the United States and Spain. Obstetrical & Gynecological Survey 2017, 72: 334-335. DOI: 10.1097/01.ogx.0000516136.75506.a3.
- Sciria C, Dreyer R, Safdar B, D'Onofrio G, Krumholz H, Spatz E. MECHANISMS OF ACUTE MYOCARDIAL INFARCTION IN YOUNG WOMEN AND DISCHARGE MEDICATION PATTERNS. Journal Of The American College Of Cardiology 2017, 69: 195. DOI: 10.1016/s0735-1097(17)33584-2.
- D’Onofrio G, Chawarski MC, O’Connor P, Pantalon MV, Busch SH, Owens PH, Hawk K, Bernstein SL, Fiellin DA. Emergency Department-Initiated Buprenorphine for Opioid Dependence with Continuation in Primary Care: Outcomes During and After Intervention. Journal Of General Internal Medicine 2017, 32: 660-666. PMID: 28194688, PMCID: PMC5442013, DOI: 10.1007/s11606-017-3993-2.
- Tomassoni AJ, Hawk KF, Jubanyik K, Nogee DP, Durant T, Lynch KL, Patel R, Dinh D, Ulrich A, D’Onofrio G. Multiple Fentanyl Overdoses — New Haven, Connecticut, June 23, 2016. MMWR Morbidity And Mortality Weekly Report 2017, 66: 107-111. PMID: 28151928, PMCID: PMC5657834, DOI: 10.15585/mm6604a4.
- Hawk K, Weiner S, Dziura J, Fiellin D, DaEun D, Nelson L, Hoppe J, Perrone J, D’Onofrio G. Prescribing opioids safely in the emergency department study: Predictors of emergency department discharge with high morphine milligram equivalent prescription. Drug And Alcohol Dependence 2017, 171: e86. DOI: 10.1016/j.drugalcdep.2016.08.242.
- Safdar B, D’Onofrio G, Dziura J, Russell RR, Johnson C, Sinusas AJ. Ranolazine and Microvascular Angina by PET in the Emergency Department: Results From a Pilot Randomized Controlled Trial. Clinical Therapeutics 2017, 39: 55-63. PMID: 28081848, PMCID: PMC10345862, DOI: 10.1016/j.clinthera.2016.12.002.
- Xu X, Bao H, Strait KM, Edmondson DE, Davidson KW, Beltrame JF, Bueno H, Lin H, Dreyer RP, Brush JE, Spertus JA, Lichtman JH, D'Onofrio G, Krumholz HM. Perceived Stress After Acute Myocardial Infarction. Psychosomatic Medicine 2017, 79: 50-58. PMID: 27984507, PMCID: PMC5459399, DOI: 10.1097/psy.0000000000000429.
- Lindau ST, Abramsohn E, Bueno H, D’Onofrio G, Lichtman JH, Lorenze NP, Sanghani RM, Spatz ES, Spertus JA, Strait KM, Wroblewski K, Zhou S, Krumholz HM. Sexual Activity and Function in the Year After an Acute Myocardial Infarction Among Younger Women and Men in the United States and Spain. JAMA Cardiology 2016, 1: 754-764. PMID: 27579897, PMCID: PMC5459405, DOI: 10.1001/jamacardio.2016.2362.
- Bucholz EM, Strait KM, Dreyer RP, Lindau ST, D’Onofrio G, Geda M, Spatz ES, Beltrame JF, Lichtman JH, Lorenze NP, Bueno H, Krumholz HM. Editor’s Choice-Sex differences in young patients with acute myocardial infarction: A VIRGO study analysis. European Heart Journal Acute Cardiovascular Care 2016, 6: 610-622. PMID: 27485141, PMCID: PMC5459677, DOI: 10.1177/2048872616661847.
- Safdar B, D’Onofrio G, Dziura J, Russell R, Naftilan M, Johnson C, Sinusas A. MICROVASCULAR ANGINA IN THE ABSENCE OF CORONARY ARTERY DISEASE IS COMMON IN UNDIFFERENTIATED CHEST PAIN PATIENTS IN THE EMERGENCY DEPARTMENT. Journal Of The American College Of Cardiology 2016, 67: 1824. DOI: 10.1016/s0735-1097(16)31825-3.
- Safdar B, Ali A, D’Onofrio G, Katz SD. Microvascular Dysfunction as Opposed to Conduit Artery Disease Explains Sex-specific Chest Pain in Emergency Department Patients With Low to Moderate Cardiac Risk. Clinical Therapeutics 2016, 38: 240-255.e1. PMID: 26778090, DOI: 10.1016/j.clinthera.2015.12.010.
- Leifheit-Limson EC, D’Onofrio G, Daneshvar M, Geda M, Bueno H, Spertus JA, Krumholz HM, Lichtman JH. Sex Differences in Cardiac Risk Factors, Perceived Risk, and Health Care Provider Discussion of Risk and Risk Modification Among Young Patients With Acute Myocardial Infarction The VIRGO Study. Journal Of The American College Of Cardiology 2015, 66: 1949-1957. PMID: 26515996, PMCID: PMC4628727, DOI: 10.1016/j.jacc.2015.08.859.
- Busch S, Hawk K, Fiellin D, O’Connor P, Chawarski M, Owens P, Pantalon M, Bernstein S, D’Onofrio G. Health service use in a randomized clinical trial comparing three methods of emergency department interventions for opioid dependence. Drug And Alcohol Dependence 2015, 156: e32. DOI: 10.1016/j.drugalcdep.2015.07.1005.
- D’Onofrio G, O’Connor P, Pantalon M, Chawarski M, Busch S, Owens P, Bernstein S, Fiellin D. A randomized clinical trial of emergency department initiated treatment for opioid dependence: Two and six month outcomes. Drug And Alcohol Dependence 2015, 156: e53. DOI: 10.1016/j.drugalcdep.2015.07.1062.
- McCormack R, Gauthier P, McClure B, Moy L, Hu M, Pavlicova M, Nunes E, Thompson D, Mandler R, Bogenschutz M, D'Onofrio G, Rotrosen J. Do chief complaints allow targeting of SBIRT in the Emergency Department? Addiction Science & Clinical Practice 2015, 10: o42. PMCID: PMC4596949, DOI: 10.1186/1940-0640-10-s2-o42.
- Fiellin DA, O’Connor P, D’Onofrio G. Opioid Dependence Treatment in the Emergency Department—Reply. JAMA 2015, 314: 835-835. PMID: 26305657, DOI: 10.1001/jama.2015.8527.
- D’Onofrio G, O’Connor P, Pantalon MV, Chawarski MC, Busch SH, Owens PH, Bernstein SL, Fiellin DA. Emergency Department–Initiated Buprenorphine/Naloxone Treatment for Opioid Dependence: A Randomized Clinical Trial. JAMA 2015, 313: 1636-1644. PMID: 25919527, PMCID: PMC4527523, DOI: 10.1001/jama.2015.3474.
- Bernstein SL, D’Onofrio G, Rosner J, O’Malley S, Makuch R, Busch S, Pantalon MV, Toll B. Successful Tobacco Dependence Treatment in Low-Income Emergency Department Patients: A Randomized Trial. Annals Of Emergency Medicine 2015, 66: 140-147. PMID: 25920384, PMCID: PMC4819432, DOI: 10.1016/j.annemergmed.2015.03.030.
- D'Onofrio G, Safdar B, Lichtman JH, Strait KM, Dreyer RP, Geda M, Spertus JA, Krumholz HM. Sex Differences in Reperfusion in Young Patients With ST-Segment–Elevation Myocardial Infarction. Circulation 2015, 131: 1324-1332. PMID: 25792558, PMCID: PMC4652789, DOI: 10.1161/circulationaha.114.012293.
- Dreyer R, Wang Y, Strait K, Lorenze N, D’Onofrio G, Bueno H, Lichtman J, Spertus J, Krumholz H. SEX DIFFERENCES IN 12-MONTH HEALTH STATUS IN YOUNG PATIENTS FOLLOWING ACUTE MYOCARDIAL INFARCTION: RESULTS FROM THE VIRGO STUDY (VARIATION IN RECOVERY: ROLE OF GENDER ON OUTCOMES OF YOUNG ACUTE MYOCARDIAL INFARCTION PATIENTS). Journal Of The American College Of Cardiology 2015, 65: a6. DOI: 10.1016/s0735-1097(15)60006-7.
- Dreyer RP, Smolderen KG, Strait KM, Beltrame JF, Lichtman JH, Lorenze NP, D’Onofrio G, Bueno H, Krumholz HM, Spertus JA. Gender differences in pre-event health status of young patients with acute myocardial infarction: A VIRGO study analysis. European Heart Journal Acute Cardiovascular Care 2015, 5: 43-54. PMID: 25681487, PMCID: PMC4658311, DOI: 10.1177/2048872615568967.
- O’Connor P, Sokol RJ, D’Onofrio G. Addiction Medicine: The Birth of a New Discipline. JAMA Internal Medicine 2014, 174: 1717-1718. PMID: 25201642, DOI: 10.1001/jamainternmed.2014.4211.
- Lord K, D'Onofrio G, Venkatesh A. 228 The Repeal of Connecticut Sunday Alcohol Sale Restrictions did not Increase Emergency Department Visitation. Annals Of Emergency Medicine 2014, 64: s82. DOI: 10.1016/j.annemergmed.2014.07.255.
- Safdar B, Bezek SK, Sinusas AJ, Russell RR, Klein MR, Dziura JD, D’onofrio G. Elevated CK-MB with a Normal Troponin Does Not Predict 30-Day Adverse Cardiac Events in Emergency Department Chest Pain Observation Unit Patients. Critical Pathways In Cardiology A Journal Of Evidence-Based Medicine 2014, 13: 14-19. PMID: 24526146, DOI: 10.1097/hpc.0000000000000001.
- Bernstein SL, D’Onofrio G. A Promising Approach For Emergency Departments To Care For Patients With Substance Use And Behavioral Disorders. Health Affairs 2013, 32: 2122-2128. PMID: 24301395, DOI: 10.1377/hlthaff.2013.0664.
- Gupta A, Wang Y, Spertus J, Geda M, Lorenze N, D'Onofrio G, Lichtman J, Krumholz H. SEX-SPECIFIC TRENDS IN HOSPITALIZATIONS AMONG YOUNG PATIENTS WITH ACUTE MYOCARDIAL INFARCTION IN UNITED STATES, 2001-2010. Journal Of The American College Of Cardiology 2013, 61: e1483. DOI: 10.1016/s0735-1097(13)61483-7.
- Vashi AA, Fox JP, Carr BG, D’Onofrio G, Pines JM, Ross JS, Gross CP. Use of Hospital-Based Acute Care Among Patients Recently Discharged From the Hospital. JAMA 2013, 309: 364-371. PMID: 23340638, PMCID: PMC3598620, DOI: 10.1001/jama.2012.216219.
- Ryan S, Martel S, Pantalon M, Martino S, Tetrault J, Thung S, Bernstein S, Auinger P, D’Onofrio G. Screening, brief intervention, and referral to treatment for alcohol and other drug use among adolescents: evaluation of a pediatric residency curriculum. Addiction Science & Clinical Practice 2012, 7: a98. PMCID: PMC3480164, DOI: 10.1186/1940-0640-7-s1-a98.
- Edelman EJ, Dinh A, Radulescu R, Lurie B, D'Onofrio G, Tetrault JM, Fiellin DA, Fiellin LE. Combining Rapid HIV Testing and a Brief Alcohol Intervention in Young Unhealthy Drinkers in the Emergency Department: A Pilot Study. The American Journal Of Drug And Alcohol Abuse 2012, 38: 539-543. PMID: 22794939, PMCID: PMC3522092, DOI: 10.3109/00952990.2012.701359.
- Ryan SA, Martel S, Pantalon M, Martino S, Tetrault J, Thung SF, Bernstein SL, Auinger P, Green ML, Fiellin DA, O'Connor P, D'Onofrio G. Screening, Brief Intervention, and Referral to Treatment (SBIRT) for Alcohol and Other Drug Use among Adolescents: Evaluation of a Pediatric Residency Curriculum. Substance Abuse 2012, 33: 251-260. PMID: 22738002, DOI: 10.1080/08897077.2011.640182.
- Tetrault JM, Green ML, Martino S, Thung SF, Degutis LC, Ryan SA, Martel S, Pantalon MV, Bernstein SL, O'Connor P, Fiellin DA, D'Onofrio G. Developing and Implementing a Multispecialty Graduate Medical Education Curriculum on Screening, Brief Intervention, and Referral to Treatment (SBIRT). Substance Abuse 2012, 33: 168-181. PMID: 22489589, DOI: 10.1080/08897077.2011.640220.
- D'Onofrio G, Fiellin DA, Pantalon MV, Chawarski MC, Owens PH, Degutis LC, Busch SH, Bernstein SL, O'Connor PG. A Brief Intervention Reduces Hazardous and Harmful Drinking in Emergency Department Patients. Annals Of Emergency Medicine 2012, 60: 181-192. PMID: 22459448, PMCID: PMC3811141, DOI: 10.1016/j.annemergmed.2012.02.006.
- D'Onofrio G, Jauch E, Jagoda A, Allen MH, Anglin D, Barsan WG, Berger RP, Bobrow BJ, Boudreaux ED, Bushnell C, Chan YF, Currier G, Eggly S, Ichord R, Larkin GL, Laskowitz D, Neumar RW, Newman-Toker DE, Quinn J, Shear K, Todd KH, Zatzick D, Participants R. NIH Roundtable on Opportunities to Advance Research on Neurologic and Psychiatric Emergencies. Annals Of Emergency Medicine 2010, 56: 551-564. PMID: 21036295, DOI: 10.1016/j.annemergmed.2010.06.562.
- Evans LV, Dodge KL, Shah TD, Kaplan LJ, Siegel MD, Moore CL, Hamann CJ, Lin Z, D'Onofrio G. Simulation Training in Central Venous Catheter Insertion: Improved Performance in Clinical Practice. Academic Medicine 2010, 85: 1462-1469. PMID: 20736674, DOI: 10.1097/acm.0b013e3181eac9a3.
- Kotlyar S, Larkin GL, Moore CL, D’Onofrio G. S100b Immunoassay: An Assessment of Diagnostic Utility in Minor Head Trauma. Journal Of Emergency Medicine 2010, 41: 285-293. PMID: 20692788, DOI: 10.1016/j.jemermed.2010.05.040.
- D’Onofrio G, Degutis LC. Integrating Project ASSERT: A Screening, Intervention, and Referral to Treatment Program for Unhealthy Alcohol and Drug Use Into an Urban Emergency Department. Academic Emergency Medicine 2010, 17: 903-911. PMID: 20670330, DOI: 10.1111/j.1553-2712.2010.00824.x.
- D’Onofrio G, Goldstein AB, Denisco RA, Hingson R, Heffelfinger JD, Post LA. Emergency Medicine Public Health Research Funded by Federal Agencies: Progress and Priorities. Academic Emergency Medicine 2009, 16: 1065-1071. PMID: 20053224, DOI: 10.1111/j.1553-2712.2009.00555.x.
- Cunningham RM, Bernstein SL, Walton M, Broderick K, Vaca FE, Woolard R, Bernstein E, Blow F, D’Onofrio G. Alcohol, Tobacco, and Other Drugs: Future Directions for Screening and Intervention in the Emergency Department. Academic Emergency Medicine 2009, 16: 1078-1088. PMID: 20053226, DOI: 10.1111/j.1553-2712.2009.00552.x.
- Broderick KB, Ranney ML, Vaca FE, D’Onofrio G, Rothman RE, Rhodes KV, Becker B, Haukoos JS. Study Designs and Evaluation Models for Emergency Department Public Health Research. Academic Emergency Medicine 2009, 16: 1124-1131. PMID: 20053232, PMCID: PMC3082772, DOI: 10.1111/j.1553-2712.2009.00557.x.
- Kirrane B, Degutis L, D'onofrio G. Alcohol and Other Drugs. 2008, 624-634. DOI: 10.1002/9781444303674.ch62.
- Kulkarni R, Pell F, Agocs-Holler E, D’Onofrio G. 227: Care Coordination in the Emergency Department: Avoiding Inappropriate Hospital Admissions. Annals Of Emergency Medicine 2007, 50: s71-s72. DOI: 10.1016/j.annemergmed.2007.06.210.
- Schuur J, Collins D, Smith A, Lisitano R, Kulkarni R, D’Onofrio G. 286: Use of Lean Techniques to Simplify Admission Procedures and Decrease ED Process Time. Annals Of Emergency Medicine 2007, 50: s90. DOI: 10.1016/j.annemergmed.2007.06.272.
- Bernstein S, Bernstein E, Boudreaux E, Babcock-Irvin C, Mello M, Kapur A, Becker B, Sattin R, Cohen V, D'Onofrio G. Public health considerations in knowledge translation in the emergency department. Academic Emergency Medicine 2007, 14: 1036-41. PMID: 17699805, DOI: 10.1197/j.aem.2007.06.012.
- Safdar B, Foody J, D'Onofrio G. Depression is a Common Coronary Risk Factor in Women Admitted to an ED Chest Pain Center. Academic Emergency Medicine 2007, 14: s131-s131. DOI: 10.1197/j.aem.2007.03.1069.
- Safdar B, Parkosewich J, Freed L, Foody J, Tandon S, Jubanyik K, Lin Z, D’Onofrio G. 375 A Multi-Faceted Community-Based Educational Program Promotes Cardiovascular Health in Women: 5 Year Analysis. Annals Of Emergency Medicine 2006, 48: 112-113. DOI: 10.1016/j.annemergmed.2006.07.841.
- Rathlev NK, Ulrich AS, Delanty N, D’Onofrio G. Alcohol-related seizures. Journal Of Emergency Medicine 2006, 31: 157-163. PMID: 17044577, DOI: 10.1016/j.jemermed.2005.09.012.
- Safdar B, Degutis LC, Landry K, Vedere SR, Moscovitz HC, D’Onofrio G. Intravenous Morphine Plus Ketorolac Is Superior to Either Drug Alone for Treatment of Acute Renal Colic. Annals Of Emergency Medicine 2006, 48: 173-181.e1. PMID: 16953530, DOI: 10.1016/j.annemergmed.2006.03.013.
- O’Rourke M, Richardson LD, Wilets I, D’Onofrio G. Alcohol-related problems: Emergency physicians’ current practice and attitudes. Journal Of Emergency Medicine 2006, 30: 263-268. PMID: 16677975, DOI: 10.1016/j.jemermed.2005.05.031.
- D'Onofrio G, Pantalon M, Degutis L, Fiellin D, O'Connor P. Development and Implementation of an Emergency Practitioner–Performed Brief Intervention for Hazardous and Harmful Drinkers in the Emergency Department. Academic Emergency Medicine 2005, 12: 249-256. DOI: 10.1111/j.1553-2712.2005.tb00879.x.
- Degutis L, Rabinovici R, Sabbaj A, Mascia R, D'Onofrio G. The saliva strip test is an accurate method to determine blood alcohol concentration in trauma patients. Academic Emergency Medicine 2004, 11: 885-7. PMID: 15289199, DOI: 10.1111/j.1553-2712.2004.tb00775.x.
- Kane B, Degutis L, Sayward H, D'Onofrio G. Compliance with the Centers for Disease Control and Prevention Recommendations for the Diagnosis and Treatment of Sexually Transmitted Diseases. Academic Emergency Medicine 2004, 11: 371-377. DOI: 10.1111/j.1553-2712.2004.tb01455.x.
- Rathlev N, Ulrich A, Shieh T, Callum M, Bernstein E, D'Onofrio G. Etiology and weekly occurrence of alcohol-related seizures. Academic Emergency Medicine 2002, 9: 824-8. PMID: 12153888, DOI: 10.1111/j.1553-2712.2002.tb02171.x.
- D'Onofrio G, Degutis L. Preventive care in the emergency department: screening and brief intervention for alcohol problems in the emergency department: a systematic review. Academic Emergency Medicine 2002, 9: 627-38. PMID: 12045080, DOI: 10.1111/j.1553-2712.2002.tb02304.x.
- D'Onofrio G, Ulrich A, Rathlev N. Alcohol and Seizures. 2001, 0: 167-182. DOI: 10.1385/1-59259-094-2:167.
- Cydulka R, D'Onofrio G, Schneider S, Emerman C, Sullivan L, Force T. Women in Academic Emergency Medicine. Academic Emergency Medicine 2000, 7: 999-1007. PMID: 11043995, DOI: 10.1111/j.1553-2712.2000.tb02091.x.
- Rathlev N, Ulrich A, Fish S, D'Onofrio G. Clinical Characteristics as Predictors of Recurrent Alcohol‐related Seizures. Academic Emergency Medicine 2000, 7: 886-891. PMID: 10958128, DOI: 10.1111/j.1553-2712.2000.tb02066.x.
- D'Onofrio G. Screening and Brief Intervention for Alcohol and Other Drug Problems: What Will It Take? Academic Emergency Medicine 2000, 7: 69-71. PMID: 10894246, DOI: 10.1111/j.1553-2712.2000.tb01896.x.
- D'Onofrio G, Rathlev N, Ulrich A, Fish S, Freedland E. Lorazepam for the Prevention of Recurrent Seizures Related to Alcohol. New England Journal Of Medicine 1999, 340: 915-919. PMID: 10094637, DOI: 10.1056/nejm199903253401203.
- D'Onofrio G, Bernstein E, Bernstein J, Woolard R, Brewer P, Craig S, Zink B, Force F. Patients with Alcohol Problems in the Emergency Department, Part 2: Intervention and Referral. Academic Emergency Medicine 1998, 5: 1210-1217. PMID: 9864135, DOI: 10.1111/j.1553-2712.1998.tb02697.x.
- D'Onofrio G, Bernstein E, Bernstein J, Woolard R, Brewer P, Craig S, Zink B, Force F. Patients with Alcohol Problems in the Emergency Department, Part 1: Improving Detection*. Academic Emergency Medicine 1998, 5: 1200-1209. PMID: 9864134, DOI: 10.1111/j.1553-2712.1998.tb02696.x.
- Burdick W, Jouriles N, D'Onofrio G, Kass L, Mahoney J, Restifo K, Committee U. Emergency Medicine in Undergraduate Education. Academic Emergency Medicine 1998, 5: 1105-1110. PMID: 9835475, DOI: 10.1111/j.1553-2712.1998.tb02671.x.
- Rathlev N, D'Onofrio G, Fish S, Harrison P, Bernstein E, Hossack R, Pickens L. The lack of efficacy of phenytoin in the prevention of recurrent alcohol-related seizures. Annals Of Emergency Medicine 1994, 23: 513-518. PMID: 8135426, DOI: 10.1016/s0196-0644(94)70070-2.
- Freedland E, McMicken D, D'Onofrio G. Alcohol and Trauma. Emergency Medicine Clinics Of North America 1993, 11: 225-239. PMID: 8432251, DOI: 10.1016/s0733-8627(20)30668-4.
- Rathlev N, D'onofrio G, Fish S. Sample size & selection criteria. Annals Of Emergency Medicine 1992, 21: 344-345. PMID: 1536500, DOI: 10.1016/s0196-0644(05)80920-5.
- Long GD. Managing the patient with abdominal aortic aneurysm. Nursing 1978, 8: 20-7. PMID: 248638.
- Adult Emergency DepartmentYale New Haven Hospital20 York Street, Ste Pavilion 218New Haven, CT 06510
- Yale New Haven Hospital and Emergency DepartmentYale New Haven Hospital20 York StreetNew Haven, CT 06510
- New London Buprenorphine Clinic931 Bank StreetNew London, CT 06320
Biography
Gail D’Onofrio, MD, MS, is an emergency medicine and addiction medicine specialist who is internationally known for her work in alcohol and other substance use disorders, and in gender variations in women with ischemic heart disease. She is the former physician-in-chief of emergency services at Yale New Haven Hospital and was the inaugural chair of the Department of Emergency Medicine at Yale School of Medicine.
Dr. D’Onofrio’s goals have always been to provide quality medical care for the wide range of people who come through the emergency department (ED) doors, whether that means resuscitating and stabilizing critically ill or injured patients, or assessing and treating nonemergent illness or injuries.
“The ED offers access to care for all—all day, all night, every day,” she says. “Our goal Is to treat the presenting problem and make connections to any services or resources our patients might need, whether they have an acute illness or injury, an addiction, or exacerbation of chronic disease such as diabetes or hypertension.”
In addition to her role as Albert E. Kent professor of emergency medicine at Yale School of Medicine, Dr. D’Onofrio holds professorships in chronic disease epidemiology in Yale School of Public Health, and in internal medicine (core faculty in addiction).
For the past 30 years she has developed and tested interventions for alcohol, opioids, and other substance use disorders, serving as the principal investigator (PI) on several large National Institutes of Health (NIH), Substance Abuse and Mental Health Services Administration (SAMSHA), and Centers for Disease Control and Prevention (CDC) studies. Her research demonstrating that ED-initiated buprenorphine increases engagement in addiction treatment for people with opioid use disorder changed clinical practice.
Dr. D’Onofrio is also a founding member of the Board of Addiction Medicine, which is now recognized by the American Board of Medical Specialties as a specialty and subspecialty through Preventive Medicine. She has worked on the state and national levels and with multiple agencies to change policies and introduce interventions to combat the opioid crisis.
Titles
- Albert E. Kent Professor of Emergency Medicine, Professor of Epidemiology (Chronic Diseases) and Professor of Medicine Core Addiction
Education & Training
- FellowSAMSHA (1997)
- ResidentBoston City Hospital (1991)
- MDBoston University School of Medicine (1987)
- MSBoston University (1975)
Additional Information
- Distinguished Alumni Award: Boston University (2022)
- Distinguished Service Award: Association of Academic Chairs of Emergency Medicine (2022)
- AB of Preventive Medicine, Addiction Medicine (Preventive Medicine) (2018)
- AB of Emergency Medicine, Emergency Medicine (1992, recertified: 2011)
- Joseph D, Brokowski C, D'Onofrio G, Bogucki S, McGovern J, Allen R, Dziura J, Cone D, Pantalon M. "SafetyNet": Evaluation of a Recovery Coach and Paramedic Intervention Following Naloxone Resuscitation From an Opioid Overdose. Substance Use & Addiction Journal 2024, 29767342241266412. PMID: 39171791, DOI: 10.1177/29767342241266412.
- Howell B, Black A, Lin H, Lauretta G, Heimer R, Hawk K, D'Onofrio G, Fiellin D, Becker W. T50 Receipt of Prescribed Opioids and Benzodiazepines After Non-Fatal Overdose and Risk of Subsequent Overdose. Drug And Alcohol Dependence 2024, 260: 110499. DOI: 10.1016/j.drugalcdep.2023.110499.
- Hawk K, D'Onofrio G, Chawarski M, Coupet E, Cowan E, Curry L, Freiermurth C, Lyons M, Murphy A, O'Connor P, Richardson L, Rothman R, Whiteside L, Williams J, Fiellin D, Edelman E. W81 Implementation Facilitation Improves Clinician Readiness to Provide Emergency Department-Initiated Buprenorphine in Four Urban Academic Centers. Drug And Alcohol Dependence 2024, 260: 110699. DOI: 10.1016/j.drugalcdep.2023.110699.
- D’Onofrio G, Herring A, Perrone J, Hawk K, Samuels E, Cowan E, Anderson E, McCormack R, Huntley K, Owens P, Martel S, Schactman M, Lofwall M, Walsh S, Dziura J, Fiellin D. Extended-Release 7-Day Injectable Buprenorphine for Patients With Minimal to Mild Opioid Withdrawal. JAMA Network Open 2024, 7: e2420702. PMID: 38976265, PMCID: PMC11231806, DOI: 10.1001/jamanetworkopen.2024.20702.
- Thompson R, Sabounchi N, Ali S, Heimer R, D’Onofrio G, Heckmann R. Using qualitative system dynamics modeling to understand overdose bystander behavior in the context of Connecticut’s Good Samaritan Laws and identify effective policy options. Harm Reduction Journal 2024, 21: 124. PMID: 38937759, PMCID: PMC11210010, DOI: 10.1186/s12954-024-00990-3.
- Savitz S, Stevens M, Nath B, D’Onofrio G, Melnick E, Jeffery M. Trends in the Prescribing of Buprenorphine for Opioid Use Disorder, 2019-2023. Mayo Clinic Proceedings Innovations Quality & Outcomes 2024, 8: 308-320. PMID: 38841599, PMCID: PMC11152959, DOI: 10.1016/j.mayocpiqo.2024.04.004.
- Kazemitabar M, Howell B, Becker W, Lin H, Grau L, Heimer R, D'Onofrio G, Hawk K, Fiellin D, Black A. Prescription Opioid Dose Change Prior to Fatal Opioid-Detected Overdose. Journal Of Studies On Alcohol And Drugs 2024 PMID: 38775307, DOI: 10.15288/jsad.24-00026.
- Zhu C, Dreyer R, Li F, Spatz E, Caraballo C, Mahajan S, Raparelli V, Leifheit E, Lu Y, Krumholz H, Spertus J, D'Onofrio G, Pilote L, Lichtman J. Association of marital/partner status with hospital readmission among young adults with acute myocardial infarction. PLOS ONE 2024, 19: e0287949. PMID: 38277368, PMCID: PMC10817183, DOI: 10.1371/journal.pone.0287949.
- Safdar B, Sobiesk M, Bertsimas D, Nowroozpoor A, Deng Y, D’Onofrio G, Dziura J, El-Khoury J, Guo X, Simonov M, Taylor R, Wang M, Desir G. Renalase Identified by Machine Learning Methods as A Novel Independent Predictor of Mortality in Hospitalized Patients with COVID-19. Journal Of Biotechnology And Biomedicine 2024, 07 DOI: 10.26502/jbb.2642-91280139.
- Heimer R, Black A, Lin H, Grau L, Fiellin D, Howell B, Hawk K, D'Onofrio G, Becker W. Receipt of opioid use disorder treatments prior to fatal overdoses and comparison to no treatment in Connecticut, 2016–17. Drug And Alcohol Dependence 2023, 254: 111040. PMID: 38043226, PMCID: PMC10872282, DOI: 10.1016/j.drugalcdep.2023.111040.
- Hawk K, Weiner S, Rothenberg C, Bernstein E, D'Onofrio G, Herring A, Hoppe J, Ketcham E, LaPietra A, Nelson L, Perrone J, Ranney M, Samuels E, Strayer R, Sharma D, Goyal P, Schuur J, Venkatesh A. Leveraging a Learning Collaborative Model to Develop and Pilot Quality Measures to Improve Opioid Prescribing in the Emergency Department. Annals Of Emergency Medicine 2023, 83: 225-234. PMID: 37831040, DOI: 10.1016/j.annemergmed.2023.08.490.
- Taylor R, Gilson A, Schulz W, Lopez K, Young P, Pandya S, Coppi A, Chartash D, Fiellin D, D’Onofrio G. Computational phenotypes for patients with opioid-related disorders presenting to the emergency department. PLOS ONE 2023, 18: e0291572. PMID: 37713393, PMCID: PMC10503758, DOI: 10.1371/journal.pone.0291572.
- D'Onofrio G, Perrone J, Hawk K, Cowan E, McCormack R, Coupet E, Owens P, Martel S, Huntley K, Walsh S, Lofwall M, Herring A, Investigators T. Early emergency department experience with 7‐day extended‐release injectable buprenorphine for opioid use disorder. Academic Emergency Medicine 2023, 30: 1264-1271. PMID: 37501652, PMCID: PMC10822018, DOI: 10.1111/acem.14782.
- Zhu C, Dreyer R, Li F, Spatz E, Caraballo‐Cordovez C, Mahajan S, Raparelli V, Leifheit E, Lu Y, Krumholz H, Spertus J, D'Onofrio G, Pilote L, Lichtman J. Impact of Marital Stress on 1‐Year Health Outcomes Among Young Adults With Acute Myocardial Infarction. Journal Of The American Heart Association 2023, 12: e030031. PMID: 37589125, PMCID: PMC10547344, DOI: 10.1161/jaha.123.030031.
- Yang D, Panthagani K, Ryus C, Nelson A, Wright D, Sherak R, Bernstein S, D'Onofrio G. Yale Emergency Scholars (YES) Program: A model for expanding emergency medicine research capacity. Academic Emergency Medicine 2023, 30: 1179-1182. PMID: 37436420, DOI: 10.1111/acem.14777.
- Jeffery M, Stevens M, D'Onofrio G, Melnick E. Fentanyl-Associated Overdose Deaths Outside the Hospital. New England Journal Of Medicine 2023, 389: 87-88. PMID: 37342960, PMCID: PMC10388669, DOI: 10.1056/nejmc2304991.
- Cowan E, Perrone J, Dziura J, Edelman E, Hawk K, Herring A, McCormack R, Murphy A, Phadke M, Fiellin D, D'Onofrio G. URINE TOXICOLOGY PROFILES OF EMERGENCY DEPARTMENT PATIENTS WITH UNTREATED OPIOID USE DISORDER: A MULTI-SITE VIEW. Journal Of Emergency Medicine 2023, 65: e357-e365. PMID: 37716904, PMCID: PMC10591927, DOI: 10.1016/j.jemermed.2023.06.007.
- Cowan E, Perrone J, Bernstein S, Coupet E, Fiellin D, Hawk K, Herring A, Huntley K, McCormack R, Venkatesh A, D'Onofrio G. National Institute on Drug Abuse Clinical Trials Network Meeting Report: Advancing Emergency Department Initiation of Buprenorphine for Opioid Use Disorder. Annals Of Emergency Medicine 2023, 82: 326-335. PMID: 37178101, PMCID: PMC10524880, DOI: 10.1016/j.annemergmed.2023.03.025.
- Justen M, Edelman E, Chawarski M, Coupet E, Cowan E, Lyons M, Owens P, Martel S, Richardson L, Rothman R, Whiteside L, O'Connor P, Zahn E, D'Onofrio G, Fiellin D, Hawk K. Perspectives on and experiences of emergency department–initiated buprenorphine among clinical pharmacists: A multi-site qualitative study. Journal Of Substance Use And Addiction Treatment 2023, 155: 209058. PMID: 37149149, DOI: 10.1016/j.josat.2023.209058.
- McCormack R, Rotrosen J, Gauthier P, D'Onofrio G, Fiellin D, Marsch L, Novo P, Liu D, Edelman E, Farkas S, Matthews A, Mulatya C, Salazar D, Wolff J, Knight R, Goodman W, Williams J, Hawk K. Implementing Programs to Initiate Buprenorphine for Opioid Use Disorder Treatment in High-Need, Low-Resource Emergency Departments: A Nonrandomized Controlled Trial. Annals Of Emergency Medicine 2023, 82: 272-287. PMID: 37140493, PMCID: PMC10524047, DOI: 10.1016/j.annemergmed.2023.02.013.
- Sawano M, Lu Y, Caraballo C, Mahajan S, Dreyer R, Lichtman J, D'Onofrio G, Spatz E, Khera R, Onuma O, Murugiah K, Spertus J, Krumholz H. Sex Difference in Outcomes of Acute Myocardial Infarction in Young Patients. Journal Of The American College Of Cardiology 2023, 81: 1797-1806. PMID: 37137590, DOI: 10.1016/j.jacc.2023.03.383.
- Sue K, Chawarski M, Curry L, McNeil R, Coupet E, Schwartz R, Wilder C, Tsui J, Hawk K, D’Onofrio G, O’Connor P, Fiellin D, Edelman E. Perspectives of Clinicians and Staff at Community-Based Opioid Use Disorder Treatment Settings on Linkages With Emergency Department–Initiated Buprenorphine Programs. JAMA Network Open 2023, 6: e2312718. PMID: 37163263, PMCID: PMC10173026, DOI: 10.1001/jamanetworkopen.2023.12718.
- Vaca F, Dziura J, Abujarad F, Pantalon M, Hsiao A, Reynolds J, Maciejewski K, Field C, D’Onofrio G. Use of an Automated Bilingual Digital Health Tool to Reduce Unhealthy Alcohol Use Among Latino Emergency Department Patients. JAMA Network Open 2023, 6: e2314848. PMID: 37219901, PMCID: PMC10208138, DOI: 10.1001/jamanetworkopen.2023.14848.
- Brush J, Chaudhry S, Dreyer R, D'Onofrio G, Greene E, Hajduk A, Lu Y, Krumholz H. Sex Differences in Symptom Complexity and Door-to-Balloon Time in Patients With ST-Elevation Myocardial Infarction. The American Journal Of Cardiology 2023, 197: 101-107. PMID: 37062667, PMCID: PMC10198892, DOI: 10.1016/j.amjcard.2023.03.009.
- D’Onofrio G, Edelman E, Hawk K, Chawarski M, Pantalon M, Owens P, Martel S, Rothman R, Saheed M, Schwartz R, Cowan E, Richardson L, Salsitz E, Lyons M, Freiermuth C, Wilder C, Whiteside L, Tsui J, Klein J, Coupet E, O’Connor P, Matthews A, Murphy S, Huntley K, Fiellin D. Implementation Facilitation to Promote Emergency Department–Initiated Buprenorphine for Opioid Use Disorder. JAMA Network Open 2023, 6: e235439. PMID: 37017967, PMCID: PMC10077107, DOI: 10.1001/jamanetworkopen.2023.5439.
- Bernstein S, Li F, Abujarad F, Grant D, D'Onofrio G, Dziura J. Modeling human health behavior with a new index that measures connectivity. Preventive Medicine Reports 2023, 33: 102172. PMID: 37223571, PMCID: PMC10201843, DOI: 10.1016/j.pmedr.2023.102172.
- D’Onofrio G, Hawk K, Perrone J, Walsh S, Lofwall M, Fiellin D, Herring A. Incidence of Precipitated Withdrawal During a Multisite Emergency Department–Initiated Buprenorphine Clinical Trial in the Era of Fentanyl. JAMA Network Open 2023, 6: e236108. PMID: 36995717, PMCID: PMC10064247, DOI: 10.1001/jamanetworkopen.2023.6108.
- Holland W, Li F, Nath B, Jeffery M, Stevens M, Melnick E, Dziura J, Khidir H, Skains R, D'Onofrio G, Soares W. Racial and ethnic disparities in emergency department–initiated buprenorphine across five health care systems. Academic Emergency Medicine 2023, 30: 709-720. PMID: 36660800, PMCID: PMC10467357, DOI: 10.1111/acem.14668.
- Hawk K, D'Onofrio G. Time to Treat Alcohol Use Disorder in the Emergency Department. Annals Of Emergency Medicine 2023, 81: 450-452. PMID: 36775724, DOI: 10.1016/j.annemergmed.2022.11.013.
- Sangal R, Rothenberg C, Hawk K, D'Onofrio G, Hsiao A, Solad Y, Venkatesh A. Real-World Observational Evaluation of Common Interventions to Reduce Emergency Department Prescribing of Opioid Medications. The Joint Commission Journal On Quality And Patient Safety 2023, 49: 239-246. PMID: 36914528, DOI: 10.1016/j.jcjq.2023.01.013.
- Okafor C, Zhu C, Raparelli V, Murphy T, Arakaki A, D’Onofrio G, Tsang S, Smith M, Lichtman J, Spertus J, Pilote L, Dreyer R. Association of Sociodemographic Characteristics With 1-Year Hospital Readmission Among Adults Aged 18 to 55 Years With Acute Myocardial Infarction. JAMA Network Open 2023, 6: e2255843. PMID: 36787140, PMCID: PMC9929697, DOI: 10.1001/jamanetworkopen.2022.55843.
- Howell B, Black A, Grau L, Lin H, Greene C, Lee H, Heimer R, Hawk K, D'Onofrio G, Fiellin D, Becker W. Concordance between controlled substance receipt and post-mortem toxicology in opioid-detected overdose deaths: A statewide analysis. Drug And Alcohol Dependence 2023, 244: 109788. PMID: 36738634, PMCID: PMC9975083, DOI: 10.1016/j.drugalcdep.2023.109788.
- Abujarad F, Choo E, Dziura J, Edwards C, Pantalon M, Jubanyik K, D'Onofrio G, Gill T. A DIGITAL ELDER ABUSE INTERVENTION FOR THE EMERGENCY DEPARTMENT. Innovation In Aging 2022, 6: 425-425. PMCID: PMC9766766, DOI: 10.1093/geroni/igac059.1669.
- Dreyer R, Arakaki A, Raparelli V, Murphy T, Tsang S, D’Onofrio G, Wood M, Wright C, Pilote L. Young Women With Acute Myocardial Infarction: Risk Prediction Model for 1-Year Hospital Readmission. CJC Open 2022, 5: 335-344. PMID: 37377522, PMCID: PMC10290947, DOI: 10.1016/j.cjco.2022.12.004.
- Taylor A, Kinsman J, Hawk K, D'Onofrio G, Malicki C, Malcom B, Goyal P, Venkatesh A. Development and testing of data infrastructure in the American College of Emergency Physicians’ Clinical Emergency Data Registry for opioid‐related research. Journal Of The American College Of Emergency Physicians Open 2022, 3: e12816. PMID: 36311336, PMCID: PMC9597093, DOI: 10.1002/emp2.12816.
- Ali S, Sabounchi N, Thompson R, Heimer R, D’Onofrio G, Heckmann R. 168 Impact of Connecticut’s Good Samaritan Laws in Preventing Opioid Overdose Deaths – An Applied System Dynamics Approach. Annals Of Emergency Medicine 2022, 80: s76-s77. DOI: 10.1016/j.annemergmed.2022.08.192.
- Lyons MS, Chawarski MC, Rothman R, Whiteside L, Cowan E, Richardson LD, Hawk K, Tsui JI, Schwartz RP, O’Connor P, D’Onofrio G, Fiellin DA, Edelman EJ. Missed Opportunities for HIV and Hepatitis C Screening Among Emergency Department Patients With Untreated Opioid Use Disorder. Journal Of Addiction Medicine 2022, 17: 210-214. PMID: 36170184, PMCID: PMC10023471, DOI: 10.1097/adm.0000000000001074.
- Kaur A, Dreyer R, Marsh T, Thanassoulis G, Raparelli V, D’Onofrio G, Engert J, Pilote L. Sex Differences in Clopidogrel Effects Among Young Patients With Acute Coronary Syndrome: A Role for Genetics? CJC Open 2022, 4: 970-978. PMID: 36444366, PMCID: PMC9700217, DOI: 10.1016/j.cjco.2022.07.013.
- Melnick ER, Nath B, Dziura JD, Casey MF, Jeffery MM, Paek H, Soares WE, Hoppe JA, Rajeevan H, Li F, Skains RM, Walter LA, Patel MD, Chari SV, Platts-Mills TF, Hess EP, D'Onofrio G. User centered clinical decision support to implement initiation of buprenorphine for opioid use disorder in the emergency department: EMBED pragmatic cluster randomized controlled trial. The BMJ 2022, 377: e069271. PMID: 35760423, PMCID: PMC9231533, DOI: 10.1136/bmj-2021-069271.
- Whiteside LK, D'Onofrio G, Fiellin DA, Edelman EJ, Richardson L, O'Connor P, Rothman RE, Cowan E, Lyons MS, Fockele CE, Saheed M, Freiermuth C, Punches BE, Guo C, Martel S, Owens PH, Coupet E, Hawk KF. Models for Implementing Emergency Department–Initiated Buprenorphine With Referral for Ongoing Medication Treatment at Emergency Department Discharge in Diverse Academic Centers. Annals Of Emergency Medicine 2022, 80: 410-419. PMID: 35752520, PMCID: PMC9588652, DOI: 10.1016/j.annemergmed.2022.05.010.
- Stevens MA, Tsai J, Savitz ST, Nath B, Melnick ER, D’Onofrio G, Jeffery MM. Trends and Disparities in Access to Buprenorphine Treatment Following an Opioid-Related Emergency Department Visit Among an Insured Cohort, 2014-2020. JAMA Network Open 2022, 5: e2215287. PMID: 35657629, PMCID: PMC9166266, DOI: 10.1001/jamanetworkopen.2022.15287.
- Safdar B, Mori M, Nowroozpoor A, Geirsson A, D'Onofrio G, Mangi AA. Clinical Profile and Sex-Specific Recovery With Cardiac Rehabilitation After Coronary Artery Bypass Grafting Surgery. Clinical Therapeutics 2022, 44: 846-858. PMID: 35570056, DOI: 10.1016/j.clinthera.2022.04.002.
- Lu Y, Li SX, Liu Y, Rodriguez F, Watson KE, Dreyer RP, Khera R, Murugiah K, D’Onofrio G, Spatz ES, Nasir K, Masoudi FA, Krumholz HM. Sex-Specific Risk Factors Associated With First Acute Myocardial Infarction in Young Adults. JAMA Network Open 2022, 5: e229953. PMID: 35503221, PMCID: PMC9066284, DOI: 10.1001/jamanetworkopen.2022.9953.
- Shenvi CL, Wang Y, Revankar R, Phillips J, Bush M, Biese KJ, Aylward A, D'Onofrio G, Platts‐Mills T. Use of a Brief Negotiation Interview in the emergency department to reduce high‐risk alcohol use among older adults: A randomized trial. Journal Of The American College Of Emergency Physicians Open 2022, 3: e12651. PMID: 35156089, PMCID: PMC8828696, DOI: 10.1002/emp2.12651.
- Rockett IRH, Jia H, Ali B, Banerjee A, Connery HS, Nolte KB, Miller T, White FMM, DiGregorio BD, Larkin GL, Stack S, Kõlves K, McHugh RK, Lulla VO, Cossman J, De Leo D, Hendricks B, Nestadt PS, Berry JH, D’Onofrio G, Caine ED. Association of State Social and Environmental Factors With Rates of Self-injury Mortality and Suicide in the United States. JAMA Network Open 2022, 5: e2146591. PMID: 35138401, PMCID: PMC8829661, DOI: 10.1001/jamanetworkopen.2021.46591.
- D'Onofrio G, Melnick ER, Hawk KF. In reply:. Annals Of Emergency Medicine 2022, 79: 219-220. PMID: 35065746, DOI: 10.1016/j.annemergmed.2021.10.022.
- Venkatesh AK, Janke AT, Kinsman J, Rothenberg C, Goyal P, Malicki C, D’Onofrio G, Taylor A, Hawk K. Emergency department utilization for substance use disorders and mental health conditions during COVID-19. PLOS ONE 2022, 17: e0262136. PMID: 35025921, PMCID: PMC8757912, DOI: 10.1371/journal.pone.0262136.
- Sabounchi NS, Heckmann R, D’Onofrio G, Walker J, Heimer R. Assessing the impact of the Good Samaritan Law in the state of Connecticut: a system dynamics approach. Health Research Policy And Systems 2022, 20: 5. PMID: 34991591, PMCID: PMC8734429, DOI: 10.1186/s12961-021-00807-w.
- Hawk K, McCormack R, Edelman EJ, Coupet E, Toledo N, Gauthier P, Rotrosen J, Chawarski M, Martel S, Owens P, Pantalon MV, O’Connor P, Whiteside LK, Cowan E, Richardson LD, Lyons MS, Rothman R, Marsch L, Fiellin DA, D’Onofrio G. Perspectives About Emergency Department Care Encounters Among Adults With Opioid Use Disorder. JAMA Network Open 2022, 5: e2144955. PMID: 35076700, PMCID: PMC8790663, DOI: 10.1001/jamanetworkopen.2021.44955.
- Taylor RA, Fiellin D, D'Onofrio G, Venkatesh A. Identifying Opioid-Related Electronic Health Record Phenotypes for Emergency Care Research and Surveillance: An Expert Consensus Driven Concept Mapping Process. Substance Abuse 2022, 43: 841-847. PMID: 35156912, DOI: 10.1080/08897077.2021.1975864.
- Abujarad F, Choo E, Dziura J, Edwards C, Pantalon M, Jubanyik K, D'Onofrio G, Gill T. Patient-Centered Digital Screener for Elder Abuse in the Emergency Department. Innovation In Aging 2021, 5: 152-152. PMCID: PMC8682507, DOI: 10.1093/geroni/igab046.580.
- Nowroozpoor A, Sharp E, Gordon R, Malicki C, Hwang U, Dziura J, D'Onofrio' G, Safdar B. Corrigendum to: Mild cognitive impairment in middle-aged adults with coronary microvascular dysfunction. European Heart Journal 2021, 43: 1776-1776. PMID: 34897369, DOI: 10.1093/eurheartj/ehab845.
- Guo CZ, D'Onofrio G, Fiellin DA, Edelman EJ, Hawk K, Herring A, McCormack R, Perrone J, Cowan E. Emergency department‐initiated buprenorphine protocols: A national evaluation. Journal Of The American College Of Emergency Physicians Open 2021, 2: e12606. PMID: 34877567, PMCID: PMC8630357, DOI: 10.1002/emp2.12606.
- Hawk K, Malicki C, Kinsman J, D’Onofrio G, Taylor A, Venkatesh A. Feasibility and acceptability of electronic administration of patient reported outcomes using mHealth platform in emergency department patients with non-medical opioid use. Addiction Science & Clinical Practice 2021, 16: 66. PMID: 34758881, PMCID: PMC8579535, DOI: 10.1186/s13722-021-00276-0.
- Nowroozpoor A, Sharp E, Gordon R, Malicki C, Hwang U, Dziura J, D'Onofrio' G, Safdar B. Mild cognitive impairment in middle-aged adults with coronary microvascular dysfunction. European Heart Journal 2021, 42: ehab724.2744. DOI: 10.1093/eurheartj/ehab724.2744.
- Raparelli V, Pilote L, Dang B, Behlouli H, Dziura JD, Bueno H, D’Onofrio G, Krumholz HM, Dreyer RP. Variations in Quality of Care by Sex and Social Determinants of Health Among Younger Adults With Acute Myocardial Infarction in the US and Canada. JAMA Network Open 2021, 4: e2128182. PMID: 34668947, PMCID: PMC8529414, DOI: 10.1001/jamanetworkopen.2021.28182.
- Scofi J, Parwani V, Rothenberg C, Patel A, Ravi S, Sevilla M, D'Onofrio G, Ulrich A, Venkatesh AK. Improving Emergency Department Throughput Using Audit-and-Feedback With Peer Comparison Among Emergency Department Physicians. Journal For Healthcare Quality 2021, 44: 69-77. PMID: 34570029, DOI: 10.1097/jhq.0000000000000329.
- Neumar RW, Blomkalns AL, Cairns CB, D’Onofrio G, Kuppermann N, Lewis RJ, Newgard CD, O’Neil B, Rathlev NK, Rothman RE, Wright DW. Emergency medicine research: 2030 strategic goals. Academic Emergency Medicine 2021, 29: 241-251. PMID: 34363718, DOI: 10.1111/acem.14367.
- Samuels E, Coupet E, D’Onofrio G. Emergency Department Treatment of Opioid Use Disorder. 2021, 57-75. DOI: 10.1007/978-3-030-80818-1_5.
- Dreyer RP, Raparelli V, Tsang SW, D’Onofrio G, Lorenze N, Xie CF, Geda M, Pilote L, Murphy TE. Development and Validation of a Risk Prediction Model for 1‐Year Readmission Among Young Adults Hospitalized for Acute Myocardial Infarction. Journal Of The American Heart Association 2021, 10: e021047. PMID: 34514837, PMCID: PMC8649501, DOI: 10.1161/jaha.121.021047.
- Raparelli V, Benea D, Smith M, Behlouli H, Murphy TE, D’Onofrio G, Pilote L, Dreyer RP. Impact of Race on the In‐Hospital Quality of Care Among Young Adults With Acute Myocardial Infarction. Journal Of The American Heart Association 2021, 10: e021408. PMID: 34431311, PMCID: PMC8649291, DOI: 10.1161/jaha.121.021408.
- Anderson ES, Chamberlin M, Zuluaga M, Ullal M, Hawk K, McCormack R, D'Onofrio G, Herring AA. Implementation of Oral and Extended-Release Naltrexone for the Treatment of Emergency Department Patients With Moderate to Severe Alcohol Use Disorder: Feasibility and Initial Outcomes. Annals Of Emergency Medicine 2021, 78: 752-758. PMID: 34353648, DOI: 10.1016/j.annemergmed.2021.05.013.
- Gaeta M, Nowroozpoor A, Dziura J, D'Onofrio G, Sinusas AJ, Safdar B. Use of peripheral arterial tonometry in detection of abnormal coronary flow reserve. Microvascular Research 2021, 138: 104223. PMID: 34256085, PMCID: PMC10227886, DOI: 10.1016/j.mvr.2021.104223.
- Herring AA, Vosooghi AA, Luftig J, Anderson ES, Zhao X, Dziura J, Hawk KF, McCormack RP, Saxon A, D’Onofrio G. High-Dose Buprenorphine Induction in the Emergency Department for Treatment of Opioid Use Disorder. JAMA Network Open 2021, 4: e2117128. PMID: 34264326, PMCID: PMC8283555, DOI: 10.1001/jamanetworkopen.2021.17128.
- Tuzzio L, Meyers CM, Dember LM, Grudzen CR, Melnick ER, Staman KL, Huang SS, Richards J, DeBar L, Vazquez MA, Green BB, Coronado GD, Jarvik JG, Braciszewski J, Ho PM, Wells BL, James K, Toto R, D’Onofrio G, Volandes A, Kuklinski MR, Catalano RF, Sterling SA, Morse EF, Curtis L, Larson EB. Accounting for quality improvement during the conduct of embedded pragmatic clinical trials within healthcare systems: NIH Collaboratory case studies. Healthcare 2021, 8: 100432. PMID: 34175091, PMCID: PMC8900087, DOI: 10.1016/j.hjdsi.2020.100432.
- Hawk K, Hoppe J, Ketcham E, LaPietra A, Moulin A, Nelson L, Schwarz E, Shahid S, Stader D, Wilson MP, D'Onofrio G. Consensus Recommendations on the Treatment of Opioid Use Disorder in the Emergency Department. Annals Of Emergency Medicine 2021, 78: 434-442. PMID: 34172303, DOI: 10.1016/j.annemergmed.2021.04.023.
- Gilson AS, Chartash D, Chang D, Hawk K, D'Onofrio G, Haimovich AD, Fiellin DA, Taylor RA. Analysis of Health Trajectories Leading to Adverse Opioid-Related Events. AMIA Joint Summits On Translational Science Proceedings 2021, 2021: 248-256. PMID: 34457139, PMCID: PMC8378649.
- D'Onofrio G, Melnick ER, Hawk KF. Improve Access to Care for Opioid Use Disorder: A Call to Eliminate the X-Waiver Requirement Now. Annals Of Emergency Medicine 2021, 78: 220-222. PMID: 33966933, PMCID: PMC8324519, DOI: 10.1016/j.annemergmed.2021.03.023.
- Kaur A, Dreyer R, Marsh T, Thanassoulis G, Raparelli V, D'Onofrio G, Engert J, Pilote L. ROLE OF GENETICS IN SEX-SPECIFIC EFFECTS OF CLOPIDOGREL ON ATHEROTHROMBOTIC EVENTS. Journal Of The American College Of Cardiology 2021, 77: 181. DOI: 10.1016/s0735-1097(21)01540-0.
- Pantalon MV, Dziura J, Li FY, D'Onofrio G, Weiss J, Bernstein SL. A Brief Negotiation Interview Adherence Scale for Smoking Cessation: A psychometric evaluation. Journal Of Substance Use And Addiction Treatment 2021, 126: 108398. PMID: 34116807, DOI: 10.1016/j.jsat.2021.108398.
- Gettel CJ, Canavan ME, D'Onofrio G, Carr BG, Venkatesh AK. Corrigendum to “Who provides what care? An analysis of clinical focus among the national emergency care workforce” [Am J Emerg Med. 2021 Apr;42:228–232]. The American Journal Of Emergency Medicine 2021, 46: 804. PMID: 33875317, PMCID: PMC8338896, DOI: 10.1016/j.ajem.2021.04.015.
- Soares WE, Melnick ER, Nath B, D'Onofrio G, Paek H, Skains RM, Walter LA, Casey MF, Napoli A, Hoppe JA, Jeffery MM. Emergency Department Visits for Nonfatal Opioid Overdose During the COVID-19 Pandemic Across Six US Health Care Systems. Annals Of Emergency Medicine 2021, 79: 158-167. PMID: 34119326, PMCID: PMC8449788, DOI: 10.1016/j.annemergmed.2021.03.013.
- D'Onofrio G, Hawk KF, Herring AA, Perrone J, Cowan E, McCormack RP, Dziura J, Taylor RA, Coupet E, Edelman EJ, Pantalon MV, Owens PH, Martel SH, O'Connor PG, Van Veldhuisen P, DeVogel N, Huntley K, Murphy SM, Lofwall MR, Walsh SL, Fiellin DA. The design and conduct of a randomized clinical trial comparing emergency department initiation of sublingual versus a 7-day extended-release injection formulation of buprenorphine for opioid use disorder: Project ED Innovation. Contemporary Clinical Trials 2021, 104: 106359. PMID: 33737199, PMCID: PMC9153252, DOI: 10.1016/j.cct.2021.106359.
- McCormack RP, Rotrosen J, Gauthier P, D’Onofrio G, Fiellin DA, Marsch LA, Novo P, Liu D, Edelman EJ, Farkas S, Matthews AG, Mulatya C, Salazar D, Wolff J, Knight R, Goodman W, Hawk K. Implementation facilitation to introduce and support emergency department-initiated buprenorphine for opioid use disorder in high need, low resource settings: protocol for multi-site implementation-feasibility study. Addiction Science & Clinical Practice 2021, 16: 16. PMID: 33750454, PMCID: PMC7941881, DOI: 10.1186/s13722-021-00224-y.
- Samuels EA, Kelley L, Pham T, Cross J, Carmona J, Ellis P, Cobbs-Lomax D, D’Onofrio G, Capp R. “I wanted to participate in my own care”: Evaluation of a Patient Navigation Program. Western Journal Of Emergency Medicine 2021, 22: 417-426. PMID: 33856334, PMCID: PMC7972383, DOI: 10.5811/westjem.2020.9.48105.
- Hawk K, Grau LE, Fiellin DA, Chawarski M, O’Connor P, Cirillo N, Breen C, D’Onofrio G. A qualitative study of emergency department patients who survived an opioid overdose: Perspectives on treatment and unmet needs. Academic Emergency Medicine 2021, 28: 542-552. PMID: 33346926, PMCID: PMC8281441, DOI: 10.1111/acem.14197.
- Rockett IRH, Caine ED, Banerjee A, Ali B, Miller T, Connery HS, Lulla VO, Nolte KB, Larkin GL, Stack S, Hendricks B, McHugh RK, White FMM, Greenfield SF, Bohnert ASB, Cossman JS, D'Onofrio G, Nelson LS, Nestadt PS, Berry JH, Jia H. Fatal self-injury in the United States, 1999–2018: Unmasking a national mental health crisis. EClinicalMedicine 2021, 32: 100741. PMID: 33681743, PMCID: PMC7910714, DOI: 10.1016/j.eclinm.2021.100741.
- Becker WC, Heimer R, Dormitzer CM, Doernberg M, D’Onofrio G, Grau LE, Hawk K, Lin HJ, Secora AM, Fiellin DA. Merging statewide data in a public/university collaboration to address opioid use disorder and overdose. Addiction Science & Clinical Practice 2021, 16: 1. PMID: 33397480, PMCID: PMC7780404, DOI: 10.1186/s13722-020-00211-9.
- Abujarad F, Choo E, Pantalon M, Jubanyik K, Dziura J, Edwards C, D’Onofrio G, Gill T. Digital Health Tool to Assist Older Adults in Self-Disclosing Elder Mistreatment. Innovation In Aging 2020, 4: 755-756. PMCID: PMC7743726, DOI: 10.1093/geroni/igaa057.2724.
- Perceived Value of Using a Digital Tool to Screen for Elder Mistreatment in the Emergency DepartmentAbujarad F, Gill T, Pantalon M, Jubanyik K, Dziura J, D’Onofrio G, Choo E. Perceived Value of Using a Digital Tool to Screen for Elder Mistreatment in the Emergency Department. Innovation In Aging 2020, 4: 195-195. PMCID: PMC7740753, DOI: 10.1093/geroni/igaa057.631.
- Coupet E, D’Onofrio G, Chawarski M, Edelman E, O’Connor P, Owens P, Martel S, Fiellin DA, Cowan E, Richardson L, Huntley K, Whiteside LK, Lyons MS, Rothman RE, Pantalon M, Hawk K. Emergency department patients with untreated opioid use disorder: A comparison of those seeking versus not seeking referral to substance use treatment. Drug And Alcohol Dependence 2020, 219: 108428. PMID: 33307301, PMCID: PMC8110210, DOI: 10.1016/j.drugalcdep.2020.108428.
- Raparelli V, Pilote L, Behlouli H, Dziura J, Bueno H, D'Onofrio G, Krumholz H, Dreyer R. The impact of sex, gender and healthcare system on quality of care among young adults with acute myocardial infarction. European Heart Journal 2020, 41: ehaa946.3175. DOI: 10.1093/ehjci/ehaa946.3175.
- Cone DC, Bogucki S, Burns K, D’Onofrio G, Hawk K, Joseph D, Fiellin DA. Naloxone Use by Emergency Medical Services During the COVID-19 Pandemic: A National Survey. Journal Of Addiction Medicine 2020, 14: e369-e371. PMID: 33031212, PMCID: PMC7647432, DOI: 10.1097/adm.0000000000000746.
- Abujarad F, Edwards C, Choo E, Pantalon M, Jubanyik K, Dziura J, D'Onofrio G, Gill T. Digital health screening tool for identification of elder mistreatment. Gerontechnology 2020, 19: 1-1. PMID: 33574738, PMCID: PMC7875481, DOI: 10.4017/gt.2020.19.s.70138.
- Rhee TG, D’Onofrio G, Fiellin DA. Trends in the Use of Buprenorphine in US Emergency Departments, 2002-2017. JAMA Network Open 2020, 3: e2021209. PMID: 33079195, PMCID: PMC7576404, DOI: 10.1001/jamanetworkopen.2020.21209.
- Jubanyik K, Choo E, Pantalon M, Dziura J, Edwards C, Gill T, D'Onofrio G, Abujarad F. 404 Emergency Department Tablet-Based Screening Tool for Elder Abuse. Annals Of Emergency Medicine 2020, 76: s154. DOI: 10.1016/j.annemergmed.2020.09.420.
- Jeffery MM, D’Onofrio G, Paek H, Platts-Mills TF, Soares WE, Hoppe JA, Genes N, Nath B, Melnick ER. Trends in Emergency Department Visits and Hospital Admissions in Health Care Systems in 5 States in the First Months of the COVID-19 Pandemic in the US. JAMA Internal Medicine 2020, 180: 1328-1333. PMID: 32744612, PMCID: PMC7400214, DOI: 10.1001/jamainternmed.2020.3288.
- Venkatesh AK, Gettel CJ, Mei H, Chou SC, Rothenberg C, Liu SL, D’Onofrio G, Lin Z, Krumholz HM. Where Skilled Nursing Facility Residents Get Acute Care: Is the Emergency Department the Medical Home? Journal Of Applied Gerontology 2020, 40: 828-836. PMID: 32842827, PMCID: PMC7904961, DOI: 10.1177/0733464820950125.
- Venkatesh A, Malicki C, Hawk K, D’Onofrio G, Kinsman J, Taylor A. Assessing the readiness of digital data infrastructure for opioid use disorder research. Addiction Science & Clinical Practice 2020, 15: 24. PMID: 32650817, PMCID: PMC7350566, DOI: 10.1186/s13722-020-00198-3.
- Venkatesh AK, Mei H, Shuling L, D’Onofrio G, Rothenberg C, Lin Z, Krumholz HM. Cross‐sectional Analysis of Emergency Department and Acute Care Utilization Among Medicare Beneficiaries. Academic Emergency Medicine 2020, 27: 570-579. PMID: 32302034, DOI: 10.1111/acem.13971.
- Hawk KF, D’Onofrio G, Chawarski MC, O’Connor P, Cowan E, Lyons MS, Richardson L, Rothman RE, Whiteside LK, Owens PH, Martel SH, Coupet E, Pantalon M, Curry L, Fiellin DA, Edelman EJ. Barriers and Facilitators to Clinician Readiness to Provide Emergency Department–Initiated Buprenorphine. JAMA Network Open 2020, 3: e204561. PMID: 32391893, PMCID: PMC7215257, DOI: 10.1001/jamanetworkopen.2020.4561.
- Melnick ER, Nath B, Ahmed OM, Brandt C, Chartash D, Dziura JD, Hess EP, Holland WC, Hoppe JA, Jeffery MM, Katsovich L, Li F, Lu CC, Maciejewski K, Maleska M, Mao JA, Martel S, Michael S, Paek H, Patel MD, Platts-Mills TF, Rajeevan H, Ray JM, Skains RM, Soares WE, Deutsch A, Solad Y, D’Onofrio G. Progress Report on EMBED: A Pragmatic Trial of User-Centered Clinical Decision Support to Implement EMergency Department-Initiated BuprenorphinE for Opioid Use Disorder †. Journal Of Psychiatry And Brain Science 2020, 2: e200003. PMID: 32309637, PMCID: PMC7164817, DOI: 10.20900/jpbs.20200003.
- Melnick ER, Holland WC, Ahmed OM, K A, Michael SS, Goldberg HS, Lagier C, D’Onofrio G, Stachowiak T, Brandt C, Solad Y. An integrated web application for decision support and automation of EHR workflow: a case study of current challenges to standards-based messaging and scalability from the EMBED trial. JAMIA Open 2019, 2: 434-439. PMID: 32025639, PMCID: PMC6994013, DOI: 10.1093/jamiaopen/ooz053.
- Hawk K, D’Onofrio G. Correction to: Emergency department screening and interventions for substance use disorders. Addiction Science & Clinical Practice 2019, 14: 26. PMID: 31311584, PMCID: PMC6636051, DOI: 10.1186/s13722-019-0155-3.
- Melnick ER, Jeffery MM, Dziura JD, Mao JA, Hess EP, Platts-Mills TF, Solad Y, Paek H, Martel S, Patel MD, Bankowski L, Lu C, Brandt C, D’Onofrio G. User-centred clinical decision support to implement emergency department-initiated buprenorphine for opioid use disorder: protocol for the pragmatic group randomised EMBED trial. BMJ Open 2019, 9: e028488. PMID: 31152039, PMCID: PMC6550013, DOI: 10.1136/bmjopen-2018-028488.
- D’Onofrio G, Edelman EJ, Hawk KF, Pantalon MV, Chawarski MC, Owens PH, Martel SH, VanVeldhuisen P, Oden N, Murphy SM, Huntley K, O’Connor P, Fiellin DA. Implementation facilitation to promote emergency department-initiated buprenorphine for opioid use disorder: protocol for a hybrid type III effectiveness-implementation study (Project ED HEALTH). Implementation Science 2019, 14: 48. PMID: 31064390, PMCID: PMC6505286, DOI: 10.1186/s13012-019-0891-5.
- Association Between Insurance Status and Access to Hospital Care in Emergency Department DispositionVenkatesh AK, Chou SC, Li SX, Choi J, Ross JS, D’Onofrio G, Krumholz HM, Dharmarajan K. Association Between Insurance Status and Access to Hospital Care in Emergency Department Disposition. JAMA Internal Medicine 2019, 179: 686-693. PMID: 30933243, PMCID: PMC6503571, DOI: 10.1001/jamainternmed.2019.0037.
- Ray JM, Ahmed OM, Solad Y, Maleska M, Martel S, Jeffery MM, Platts-Mills TF, Hess EP, D’Onofrio G, Melnick ER. Computerized Clinical Decision Support System for Emergency Department–Initiated Buprenorphine for Opioid Use Disorder: User-Centered Design. JMIR Human Factors 2019, 6: e13121. PMID: 30810531, PMCID: PMC6414819, DOI: 10.2196/13121.
- Samuels EA, D'Onofrio G, Huntley K, Levin S, Schuur JD, Bart G, Hawk K, Tai B, Campbell CI, Venkatesh AK. A Quality Framework for Emergency Department Treatment of Opioid Use Disorder. Annals Of Emergency Medicine 2018, 73: 237-247. PMID: 30318376, PMCID: PMC6817947, DOI: 10.1016/j.annemergmed.2018.08.439.
- Zogg C, Rook J, Schlesinger M, Schwartz J, Henschen B, Winkelman T, Haider A, D'Onofrio G. 2EMF Understanding Emergency Medicine Providers’ Perceptions of the ACA in a Renewed Era of Health Care Reform: National Survey and Qualitative Mixed-Methods Approach. Annals Of Emergency Medicine 2018, 72: s154. DOI: 10.1016/j.annemergmed.2018.08.399.
- Zogg C, Rook J, Das B, Schlesinger M, Schwartz J, Haider A, D’Onofrio G. 301 United States Emergency Medicine Providers' Perceptions of Health Care Disparities: A National Survey. Annals Of Emergency Medicine 2018, 72: s118-s119. DOI: 10.1016/j.annemergmed.2018.08.306.
- Hawk K, D’Onofrio G. Emergency department screening and interventions for substance use disorders. Addiction Science & Clinical Practice 2018, 13: 18. PMID: 30078375, PMCID: PMC6077851, DOI: 10.1186/s13722-018-0117-1.
- Safdar B, Spatz ES, Dreyer RP, Beltrame JF, Lichtman JH, Spertus JA, Reynolds HR, Geda M, Bueno H, Dziura JD, Krumholz HM, D'Onofrio G. Presentation, Clinical Profile, and Prognosis of Young Patients With Myocardial Infarction With Nonobstructive Coronary Arteries (MINOCA): Results From the VIRGO Study. Journal Of The American Heart Association 2018, 7: e009174. PMID: 29954744, PMCID: PMC6064896, DOI: 10.1161/jaha.118.009174.
- Safdar B, D’Onofrio G, Dziura J, Russell RR, Johnson C, Sinusas AJ. Prevalence and characteristics of coronary microvascular dysfunction among chest pain patients in the emergency department. European Heart Journal Acute Cardiovascular Care 2018, 9: 5-13. PMID: 29543037, DOI: 10.1177/2048872618764418.
- Lichtman JH, Leifheit EC, Safdar B, Bao H, Krumholz HM, Lorenze NP, Daneshvar M, Spertus JA, D'Onofrio G. Sex Differences in the Presentation and Perception of Symptoms Among Young Patients With Myocardial Infarction. Circulation 2018, 137: 781-790. PMID: 29459463, PMCID: PMC5822747, DOI: 10.1161/circulationaha.117.031650.
- Rockett IRH, Caine ED, Connery HS, D’Onofrio G, Gunnell DJ, Miller TR, Nolte KB, Kaplan MS, Kapusta ND, Lilly CL, Nelson LS, Putnam SL, Stack S, Värnik P, Webster LR, Jia H. Discerning suicide in drug intoxication deaths: Paucity and primacy of suicide notes and psychiatric history. PLOS ONE 2018, 13: e0190200. PMID: 29320540, PMCID: PMC5761891, DOI: 10.1371/journal.pone.0190200.
- Kim Y, Hogan K, D’Onofrio G, Chekijian S, Safdar B. Patient Ethnicity Predicts Poor Health Access and Gaps in Perception of Personal Cardiovascular Risk Factors. Critical Pathways In Cardiology A Journal Of Evidence-Based Medicine 2017, 16: 147-157. PMID: 29135623, DOI: 10.1097/hpc.0000000000000132.
- Busch SH, Fiellin DA, Chawarski MC, Owens PH, Pantalon MV, Hawk K, Bernstein SL, O'Connor PG, D'Onofrio G. Cost‐effectiveness of emergency department‐initiated treatment for opioid dependence. Addiction 2017, 112: 2002-2010. PMID: 28815789, PMCID: PMC5657503, DOI: 10.1111/add.13900.
- Bernstein SL, D’Onofrio G. Screening, treatment initiation, and referral for substance use disorders. Addiction Science & Clinical Practice 2017, 12: 18. PMID: 28780906, PMCID: PMC5545867, DOI: 10.1186/s13722-017-0083-z.
- Lindau S, Abramsohn E, Bueno H, D’Onofrio G, Lichtman J, Lorenze N, Sanghani R, Spatz E, Spertus J, Strait K, Wroblewski K, Zhou S, Krumholz H. Sexual Activity and Function in the Year After an Acute Myocardial Infarction Among Younger Women and Men in the United States and Spain. Obstetrical & Gynecological Survey 2017, 72: 334-335. DOI: 10.1097/01.ogx.0000516136.75506.a3.
- Sciria C, Dreyer R, Safdar B, D'Onofrio G, Krumholz H, Spatz E. MECHANISMS OF ACUTE MYOCARDIAL INFARCTION IN YOUNG WOMEN AND DISCHARGE MEDICATION PATTERNS. Journal Of The American College Of Cardiology 2017, 69: 195. DOI: 10.1016/s0735-1097(17)33584-2.
- D’Onofrio G, Chawarski MC, O’Connor P, Pantalon MV, Busch SH, Owens PH, Hawk K, Bernstein SL, Fiellin DA. Emergency Department-Initiated Buprenorphine for Opioid Dependence with Continuation in Primary Care: Outcomes During and After Intervention. Journal Of General Internal Medicine 2017, 32: 660-666. PMID: 28194688, PMCID: PMC5442013, DOI: 10.1007/s11606-017-3993-2.
- Tomassoni AJ, Hawk KF, Jubanyik K, Nogee DP, Durant T, Lynch KL, Patel R, Dinh D, Ulrich A, D’Onofrio G. Multiple Fentanyl Overdoses — New Haven, Connecticut, June 23, 2016. MMWR Morbidity And Mortality Weekly Report 2017, 66: 107-111. PMID: 28151928, PMCID: PMC5657834, DOI: 10.15585/mm6604a4.
- Hawk K, Weiner S, Dziura J, Fiellin D, DaEun D, Nelson L, Hoppe J, Perrone J, D’Onofrio G. Prescribing opioids safely in the emergency department study: Predictors of emergency department discharge with high morphine milligram equivalent prescription. Drug And Alcohol Dependence 2017, 171: e86. DOI: 10.1016/j.drugalcdep.2016.08.242.
- Safdar B, D’Onofrio G, Dziura J, Russell RR, Johnson C, Sinusas AJ. Ranolazine and Microvascular Angina by PET in the Emergency Department: Results From a Pilot Randomized Controlled Trial. Clinical Therapeutics 2017, 39: 55-63. PMID: 28081848, PMCID: PMC10345862, DOI: 10.1016/j.clinthera.2016.12.002.
- Xu X, Bao H, Strait KM, Edmondson DE, Davidson KW, Beltrame JF, Bueno H, Lin H, Dreyer RP, Brush JE, Spertus JA, Lichtman JH, D'Onofrio G, Krumholz HM. Perceived Stress After Acute Myocardial Infarction. Psychosomatic Medicine 2017, 79: 50-58. PMID: 27984507, PMCID: PMC5459399, DOI: 10.1097/psy.0000000000000429.
- Lindau ST, Abramsohn E, Bueno H, D’Onofrio G, Lichtman JH, Lorenze NP, Sanghani RM, Spatz ES, Spertus JA, Strait KM, Wroblewski K, Zhou S, Krumholz HM. Sexual Activity and Function in the Year After an Acute Myocardial Infarction Among Younger Women and Men in the United States and Spain. JAMA Cardiology 2016, 1: 754-764. PMID: 27579897, PMCID: PMC5459405, DOI: 10.1001/jamacardio.2016.2362.
- Bucholz EM, Strait KM, Dreyer RP, Lindau ST, D’Onofrio G, Geda M, Spatz ES, Beltrame JF, Lichtman JH, Lorenze NP, Bueno H, Krumholz HM. Editor’s Choice-Sex differences in young patients with acute myocardial infarction: A VIRGO study analysis. European Heart Journal Acute Cardiovascular Care 2016, 6: 610-622. PMID: 27485141, PMCID: PMC5459677, DOI: 10.1177/2048872616661847.
- Safdar B, D’Onofrio G, Dziura J, Russell R, Naftilan M, Johnson C, Sinusas A. MICROVASCULAR ANGINA IN THE ABSENCE OF CORONARY ARTERY DISEASE IS COMMON IN UNDIFFERENTIATED CHEST PAIN PATIENTS IN THE EMERGENCY DEPARTMENT. Journal Of The American College Of Cardiology 2016, 67: 1824. DOI: 10.1016/s0735-1097(16)31825-3.
- Safdar B, Ali A, D’Onofrio G, Katz SD. Microvascular Dysfunction as Opposed to Conduit Artery Disease Explains Sex-specific Chest Pain in Emergency Department Patients With Low to Moderate Cardiac Risk. Clinical Therapeutics 2016, 38: 240-255.e1. PMID: 26778090, DOI: 10.1016/j.clinthera.2015.12.010.
- Leifheit-Limson EC, D’Onofrio G, Daneshvar M, Geda M, Bueno H, Spertus JA, Krumholz HM, Lichtman JH. Sex Differences in Cardiac Risk Factors, Perceived Risk, and Health Care Provider Discussion of Risk and Risk Modification Among Young Patients With Acute Myocardial Infarction The VIRGO Study. Journal Of The American College Of Cardiology 2015, 66: 1949-1957. PMID: 26515996, PMCID: PMC4628727, DOI: 10.1016/j.jacc.2015.08.859.
- Busch S, Hawk K, Fiellin D, O’Connor P, Chawarski M, Owens P, Pantalon M, Bernstein S, D’Onofrio G. Health service use in a randomized clinical trial comparing three methods of emergency department interventions for opioid dependence. Drug And Alcohol Dependence 2015, 156: e32. DOI: 10.1016/j.drugalcdep.2015.07.1005.
- D’Onofrio G, O’Connor P, Pantalon M, Chawarski M, Busch S, Owens P, Bernstein S, Fiellin D. A randomized clinical trial of emergency department initiated treatment for opioid dependence: Two and six month outcomes. Drug And Alcohol Dependence 2015, 156: e53. DOI: 10.1016/j.drugalcdep.2015.07.1062.
- McCormack R, Gauthier P, McClure B, Moy L, Hu M, Pavlicova M, Nunes E, Thompson D, Mandler R, Bogenschutz M, D'Onofrio G, Rotrosen J. Do chief complaints allow targeting of SBIRT in the Emergency Department? Addiction Science & Clinical Practice 2015, 10: o42. PMCID: PMC4596949, DOI: 10.1186/1940-0640-10-s2-o42.
- Fiellin DA, O’Connor P, D’Onofrio G. Opioid Dependence Treatment in the Emergency Department—Reply. JAMA 2015, 314: 835-835. PMID: 26305657, DOI: 10.1001/jama.2015.8527.
- D’Onofrio G, O’Connor P, Pantalon MV, Chawarski MC, Busch SH, Owens PH, Bernstein SL, Fiellin DA. Emergency Department–Initiated Buprenorphine/Naloxone Treatment for Opioid Dependence: A Randomized Clinical Trial. JAMA 2015, 313: 1636-1644. PMID: 25919527, PMCID: PMC4527523, DOI: 10.1001/jama.2015.3474.
- Bernstein SL, D’Onofrio G, Rosner J, O’Malley S, Makuch R, Busch S, Pantalon MV, Toll B. Successful Tobacco Dependence Treatment in Low-Income Emergency Department Patients: A Randomized Trial. Annals Of Emergency Medicine 2015, 66: 140-147. PMID: 25920384, PMCID: PMC4819432, DOI: 10.1016/j.annemergmed.2015.03.030.
- D'Onofrio G, Safdar B, Lichtman JH, Strait KM, Dreyer RP, Geda M, Spertus JA, Krumholz HM. Sex Differences in Reperfusion in Young Patients With ST-Segment–Elevation Myocardial Infarction. Circulation 2015, 131: 1324-1332. PMID: 25792558, PMCID: PMC4652789, DOI: 10.1161/circulationaha.114.012293.
- Dreyer R, Wang Y, Strait K, Lorenze N, D’Onofrio G, Bueno H, Lichtman J, Spertus J, Krumholz H. SEX DIFFERENCES IN 12-MONTH HEALTH STATUS IN YOUNG PATIENTS FOLLOWING ACUTE MYOCARDIAL INFARCTION: RESULTS FROM THE VIRGO STUDY (VARIATION IN RECOVERY: ROLE OF GENDER ON OUTCOMES OF YOUNG ACUTE MYOCARDIAL INFARCTION PATIENTS). Journal Of The American College Of Cardiology 2015, 65: a6. DOI: 10.1016/s0735-1097(15)60006-7.
- Dreyer RP, Smolderen KG, Strait KM, Beltrame JF, Lichtman JH, Lorenze NP, D’Onofrio G, Bueno H, Krumholz HM, Spertus JA. Gender differences in pre-event health status of young patients with acute myocardial infarction: A VIRGO study analysis. European Heart Journal Acute Cardiovascular Care 2015, 5: 43-54. PMID: 25681487, PMCID: PMC4658311, DOI: 10.1177/2048872615568967.
- O’Connor P, Sokol RJ, D’Onofrio G. Addiction Medicine: The Birth of a New Discipline. JAMA Internal Medicine 2014, 174: 1717-1718. PMID: 25201642, DOI: 10.1001/jamainternmed.2014.4211.
- Lord K, D'Onofrio G, Venkatesh A. 228 The Repeal of Connecticut Sunday Alcohol Sale Restrictions did not Increase Emergency Department Visitation. Annals Of Emergency Medicine 2014, 64: s82. DOI: 10.1016/j.annemergmed.2014.07.255.
- Safdar B, Bezek SK, Sinusas AJ, Russell RR, Klein MR, Dziura JD, D’onofrio G. Elevated CK-MB with a Normal Troponin Does Not Predict 30-Day Adverse Cardiac Events in Emergency Department Chest Pain Observation Unit Patients. Critical Pathways In Cardiology A Journal Of Evidence-Based Medicine 2014, 13: 14-19. PMID: 24526146, DOI: 10.1097/hpc.0000000000000001.
- Bernstein SL, D’Onofrio G. A Promising Approach For Emergency Departments To Care For Patients With Substance Use And Behavioral Disorders. Health Affairs 2013, 32: 2122-2128. PMID: 24301395, DOI: 10.1377/hlthaff.2013.0664.
- Gupta A, Wang Y, Spertus J, Geda M, Lorenze N, D'Onofrio G, Lichtman J, Krumholz H. SEX-SPECIFIC TRENDS IN HOSPITALIZATIONS AMONG YOUNG PATIENTS WITH ACUTE MYOCARDIAL INFARCTION IN UNITED STATES, 2001-2010. Journal Of The American College Of Cardiology 2013, 61: e1483. DOI: 10.1016/s0735-1097(13)61483-7.
- Vashi AA, Fox JP, Carr BG, D’Onofrio G, Pines JM, Ross JS, Gross CP. Use of Hospital-Based Acute Care Among Patients Recently Discharged From the Hospital. JAMA 2013, 309: 364-371. PMID: 23340638, PMCID: PMC3598620, DOI: 10.1001/jama.2012.216219.
- Ryan S, Martel S, Pantalon M, Martino S, Tetrault J, Thung S, Bernstein S, Auinger P, D’Onofrio G. Screening, brief intervention, and referral to treatment for alcohol and other drug use among adolescents: evaluation of a pediatric residency curriculum. Addiction Science & Clinical Practice 2012, 7: a98. PMCID: PMC3480164, DOI: 10.1186/1940-0640-7-s1-a98.
- Edelman EJ, Dinh A, Radulescu R, Lurie B, D'Onofrio G, Tetrault JM, Fiellin DA, Fiellin LE. Combining Rapid HIV Testing and a Brief Alcohol Intervention in Young Unhealthy Drinkers in the Emergency Department: A Pilot Study. The American Journal Of Drug And Alcohol Abuse 2012, 38: 539-543. PMID: 22794939, PMCID: PMC3522092, DOI: 10.3109/00952990.2012.701359.
- Ryan SA, Martel S, Pantalon M, Martino S, Tetrault J, Thung SF, Bernstein SL, Auinger P, Green ML, Fiellin DA, O'Connor P, D'Onofrio G. Screening, Brief Intervention, and Referral to Treatment (SBIRT) for Alcohol and Other Drug Use among Adolescents: Evaluation of a Pediatric Residency Curriculum. Substance Abuse 2012, 33: 251-260. PMID: 22738002, DOI: 10.1080/08897077.2011.640182.
- Tetrault JM, Green ML, Martino S, Thung SF, Degutis LC, Ryan SA, Martel S, Pantalon MV, Bernstein SL, O'Connor P, Fiellin DA, D'Onofrio G. Developing and Implementing a Multispecialty Graduate Medical Education Curriculum on Screening, Brief Intervention, and Referral to Treatment (SBIRT). Substance Abuse 2012, 33: 168-181. PMID: 22489589, DOI: 10.1080/08897077.2011.640220.
- D'Onofrio G, Fiellin DA, Pantalon MV, Chawarski MC, Owens PH, Degutis LC, Busch SH, Bernstein SL, O'Connor PG. A Brief Intervention Reduces Hazardous and Harmful Drinking in Emergency Department Patients. Annals Of Emergency Medicine 2012, 60: 181-192. PMID: 22459448, PMCID: PMC3811141, DOI: 10.1016/j.annemergmed.2012.02.006.
- D'Onofrio G, Jauch E, Jagoda A, Allen MH, Anglin D, Barsan WG, Berger RP, Bobrow BJ, Boudreaux ED, Bushnell C, Chan YF, Currier G, Eggly S, Ichord R, Larkin GL, Laskowitz D, Neumar RW, Newman-Toker DE, Quinn J, Shear K, Todd KH, Zatzick D, Participants R. NIH Roundtable on Opportunities to Advance Research on Neurologic and Psychiatric Emergencies. Annals Of Emergency Medicine 2010, 56: 551-564. PMID: 21036295, DOI: 10.1016/j.annemergmed.2010.06.562.
- Evans LV, Dodge KL, Shah TD, Kaplan LJ, Siegel MD, Moore CL, Hamann CJ, Lin Z, D'Onofrio G. Simulation Training in Central Venous Catheter Insertion: Improved Performance in Clinical Practice. Academic Medicine 2010, 85: 1462-1469. PMID: 20736674, DOI: 10.1097/acm.0b013e3181eac9a3.
- Kotlyar S, Larkin GL, Moore CL, D’Onofrio G. S100b Immunoassay: An Assessment of Diagnostic Utility in Minor Head Trauma. Journal Of Emergency Medicine 2010, 41: 285-293. PMID: 20692788, DOI: 10.1016/j.jemermed.2010.05.040.
- D’Onofrio G, Degutis LC. Integrating Project ASSERT: A Screening, Intervention, and Referral to Treatment Program for Unhealthy Alcohol and Drug Use Into an Urban Emergency Department. Academic Emergency Medicine 2010, 17: 903-911. PMID: 20670330, DOI: 10.1111/j.1553-2712.2010.00824.x.
- D’Onofrio G, Goldstein AB, Denisco RA, Hingson R, Heffelfinger JD, Post LA. Emergency Medicine Public Health Research Funded by Federal Agencies: Progress and Priorities. Academic Emergency Medicine 2009, 16: 1065-1071. PMID: 20053224, DOI: 10.1111/j.1553-2712.2009.00555.x.
- Cunningham RM, Bernstein SL, Walton M, Broderick K, Vaca FE, Woolard R, Bernstein E, Blow F, D’Onofrio G. Alcohol, Tobacco, and Other Drugs: Future Directions for Screening and Intervention in the Emergency Department. Academic Emergency Medicine 2009, 16: 1078-1088. PMID: 20053226, DOI: 10.1111/j.1553-2712.2009.00552.x.
- Broderick KB, Ranney ML, Vaca FE, D’Onofrio G, Rothman RE, Rhodes KV, Becker B, Haukoos JS. Study Designs and Evaluation Models for Emergency Department Public Health Research. Academic Emergency Medicine 2009, 16: 1124-1131. PMID: 20053232, PMCID: PMC3082772, DOI: 10.1111/j.1553-2712.2009.00557.x.
- Kirrane B, Degutis L, D'onofrio G. Alcohol and Other Drugs. 2008, 624-634. DOI: 10.1002/9781444303674.ch62.
- Kulkarni R, Pell F, Agocs-Holler E, D’Onofrio G. 227: Care Coordination in the Emergency Department: Avoiding Inappropriate Hospital Admissions. Annals Of Emergency Medicine 2007, 50: s71-s72. DOI: 10.1016/j.annemergmed.2007.06.210.
- Schuur J, Collins D, Smith A, Lisitano R, Kulkarni R, D’Onofrio G. 286: Use of Lean Techniques to Simplify Admission Procedures and Decrease ED Process Time. Annals Of Emergency Medicine 2007, 50: s90. DOI: 10.1016/j.annemergmed.2007.06.272.
- Bernstein S, Bernstein E, Boudreaux E, Babcock-Irvin C, Mello M, Kapur A, Becker B, Sattin R, Cohen V, D'Onofrio G. Public health considerations in knowledge translation in the emergency department. Academic Emergency Medicine 2007, 14: 1036-41. PMID: 17699805, DOI: 10.1197/j.aem.2007.06.012.
- Safdar B, Foody J, D'Onofrio G. Depression is a Common Coronary Risk Factor in Women Admitted to an ED Chest Pain Center. Academic Emergency Medicine 2007, 14: s131-s131. DOI: 10.1197/j.aem.2007.03.1069.
- Safdar B, Parkosewich J, Freed L, Foody J, Tandon S, Jubanyik K, Lin Z, D’Onofrio G. 375 A Multi-Faceted Community-Based Educational Program Promotes Cardiovascular Health in Women: 5 Year Analysis. Annals Of Emergency Medicine 2006, 48: 112-113. DOI: 10.1016/j.annemergmed.2006.07.841.
- Rathlev NK, Ulrich AS, Delanty N, D’Onofrio G. Alcohol-related seizures. Journal Of Emergency Medicine 2006, 31: 157-163. PMID: 17044577, DOI: 10.1016/j.jemermed.2005.09.012.
- Safdar B, Degutis LC, Landry K, Vedere SR, Moscovitz HC, D’Onofrio G. Intravenous Morphine Plus Ketorolac Is Superior to Either Drug Alone for Treatment of Acute Renal Colic. Annals Of Emergency Medicine 2006, 48: 173-181.e1. PMID: 16953530, DOI: 10.1016/j.annemergmed.2006.03.013.
- O’Rourke M, Richardson LD, Wilets I, D’Onofrio G. Alcohol-related problems: Emergency physicians’ current practice and attitudes. Journal Of Emergency Medicine 2006, 30: 263-268. PMID: 16677975, DOI: 10.1016/j.jemermed.2005.05.031.
- D'Onofrio G, Pantalon M, Degutis L, Fiellin D, O'Connor P. Development and Implementation of an Emergency Practitioner–Performed Brief Intervention for Hazardous and Harmful Drinkers in the Emergency Department. Academic Emergency Medicine 2005, 12: 249-256. DOI: 10.1111/j.1553-2712.2005.tb00879.x.
- Degutis L, Rabinovici R, Sabbaj A, Mascia R, D'Onofrio G. The saliva strip test is an accurate method to determine blood alcohol concentration in trauma patients. Academic Emergency Medicine 2004, 11: 885-7. PMID: 15289199, DOI: 10.1111/j.1553-2712.2004.tb00775.x.
- Kane B, Degutis L, Sayward H, D'Onofrio G. Compliance with the Centers for Disease Control and Prevention Recommendations for the Diagnosis and Treatment of Sexually Transmitted Diseases. Academic Emergency Medicine 2004, 11: 371-377. DOI: 10.1111/j.1553-2712.2004.tb01455.x.
- Rathlev N, Ulrich A, Shieh T, Callum M, Bernstein E, D'Onofrio G. Etiology and weekly occurrence of alcohol-related seizures. Academic Emergency Medicine 2002, 9: 824-8. PMID: 12153888, DOI: 10.1111/j.1553-2712.2002.tb02171.x.
- D'Onofrio G, Degutis L. Preventive care in the emergency department: screening and brief intervention for alcohol problems in the emergency department: a systematic review. Academic Emergency Medicine 2002, 9: 627-38. PMID: 12045080, DOI: 10.1111/j.1553-2712.2002.tb02304.x.
- D'Onofrio G, Ulrich A, Rathlev N. Alcohol and Seizures. 2001, 0: 167-182. DOI: 10.1385/1-59259-094-2:167.
- Cydulka R, D'Onofrio G, Schneider S, Emerman C, Sullivan L, Force T. Women in Academic Emergency Medicine. Academic Emergency Medicine 2000, 7: 999-1007. PMID: 11043995, DOI: 10.1111/j.1553-2712.2000.tb02091.x.
- Rathlev N, Ulrich A, Fish S, D'Onofrio G. Clinical Characteristics as Predictors of Recurrent Alcohol‐related Seizures. Academic Emergency Medicine 2000, 7: 886-891. PMID: 10958128, DOI: 10.1111/j.1553-2712.2000.tb02066.x.
- D'Onofrio G. Screening and Brief Intervention for Alcohol and Other Drug Problems: What Will It Take? Academic Emergency Medicine 2000, 7: 69-71. PMID: 10894246, DOI: 10.1111/j.1553-2712.2000.tb01896.x.
- D'Onofrio G, Rathlev N, Ulrich A, Fish S, Freedland E. Lorazepam for the Prevention of Recurrent Seizures Related to Alcohol. New England Journal Of Medicine 1999, 340: 915-919. PMID: 10094637, DOI: 10.1056/nejm199903253401203.
- D'Onofrio G, Bernstein E, Bernstein J, Woolard R, Brewer P, Craig S, Zink B, Force F. Patients with Alcohol Problems in the Emergency Department, Part 2: Intervention and Referral. Academic Emergency Medicine 1998, 5: 1210-1217. PMID: 9864135, DOI: 10.1111/j.1553-2712.1998.tb02697.x.
- D'Onofrio G, Bernstein E, Bernstein J, Woolard R, Brewer P, Craig S, Zink B, Force F. Patients with Alcohol Problems in the Emergency Department, Part 1: Improving Detection*. Academic Emergency Medicine 1998, 5: 1200-1209. PMID: 9864134, DOI: 10.1111/j.1553-2712.1998.tb02696.x.
- Burdick W, Jouriles N, D'Onofrio G, Kass L, Mahoney J, Restifo K, Committee U. Emergency Medicine in Undergraduate Education. Academic Emergency Medicine 1998, 5: 1105-1110. PMID: 9835475, DOI: 10.1111/j.1553-2712.1998.tb02671.x.
- Rathlev N, D'Onofrio G, Fish S, Harrison P, Bernstein E, Hossack R, Pickens L. The lack of efficacy of phenytoin in the prevention of recurrent alcohol-related seizures. Annals Of Emergency Medicine 1994, 23: 513-518. PMID: 8135426, DOI: 10.1016/s0196-0644(94)70070-2.
- Freedland E, McMicken D, D'Onofrio G. Alcohol and Trauma. Emergency Medicine Clinics Of North America 1993, 11: 225-239. PMID: 8432251, DOI: 10.1016/s0733-8627(20)30668-4.
- Rathlev N, D'onofrio G, Fish S. Sample size & selection criteria. Annals Of Emergency Medicine 1992, 21: 344-345. PMID: 1536500, DOI: 10.1016/s0196-0644(05)80920-5.
- Long GD. Managing the patient with abdominal aortic aneurysm. Nursing 1978, 8: 20-7. PMID: 248638.
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