- Yale Medicine Fertility Center200 West Campus DriveFl 2Orange, CT 06477
David Seifer, MD
Biography
As a reproductive endocrinologist and infertility specialist, David B. Seifer, MD, sees himself as a liaison. His goal is to help his patients choose the right medical approach, while respecting their personal values.
“When I first meet with a couple or an individual, we talk. Over the course of an hour, I get an idea of their world view, how they envision their future and their hopes for a family,” Dr. Seifer says. “I then figure out how to apply the technology we have at our disposal to their individual needs. That might mean egg freezing for women who are concerned about future fertility but aren’t ready to conceive now. We also have egg donor and surrogate options for women of advanced maternal age or for same-sex couples.”
Dr. Seifer says he was drawn to the field of obstetrics and gynecology in medical school. “It was an epiphany when I realized how appreciative patients were,” he says. “To have someone let you into their life during such an important time, and to be able to make an impact, is such a joy.”
The dawn of in vitro fertilization (IVF) was occurring around the time Dr. Seifer completed his medical degree. “There was such excitement, like science fiction becoming a reality,” he says. “It’s a convergence of technology and biology, and I was excited to practice it and help build families.”
Plus, he enjoys working with patients who are as motivated as he is to reach a successful outcome. “Everybody is moving in the same direction,” says Dr. Seifer, who primarily sees patients in Yale Fertility Center’s Orange office, which he describes as a comfortable, calming place. “We take care of everything that may seem daunting in an efficient, relaxed way.”
Dr. Seifer’s research include the mechanisms of reproductive aging. In fact, his research led to a simple blood test used worldwide today that helps determine the health of a woman’s ovaries and a rough estimate of her egg count. He is also president of the Society for Assisted Reproductive Technology, the primary, national organization that sets clinical and laboratory guidelines and standards for safety and quality metrics for the practice of IVF.
Titles
- Professor of Obstetrics, Gynecology & Reproductive Sciences
- Fellowship Director, Reproductive Endocrinology & Infertility
Education & Training
- MDUniversity of Illinois - Chicago, Medicine (1981)
Additional Information
- Ferring Innovation Grant for Racial Equality in Reproductive Medicine and Maternal Health (2021-22): Ferring Pharmaceuticals (2021)
- Connecticut Top Docs: Connecticut Magazine (2021), (2022)
- Prize Paper Awards for SART and ASRM - Co-author: ASRM (2020)
- Prize Paper Award for Health Care Disparities- Co-author: ASRM (2019), (2022)
- Titus Fellowship Award: Yale School of Medicine (2019)
- ASRM Star Award: American Society of Reproductive Medicine (2016), (2017), (2018), (2019), (2020), (2021), (2022)
- America’s Top Doctors Castle Connolly Medical Guide for 12 years: Castle Connolly (2014)
- Thomas Alva Edison Patent Award: Research and Development Council of New Jersey (2011)
- Inventor of the Year Award: New Jersey Inventors Hall of Fame (2011)
- Life Teacher Award: Maimonides Medical Center (2007)
- Society for Assisted Reproductive Technology (SART) (2017 - 2021): President of SART 2017-2018; Member of Presidential and Executive Council of Society for Assisted Reproductive Technology (SART) 2016 - 2021.
- Reproductive Biology and Endocrinology (2016 - Present): Co-Editor-in-Chief
- NICHD – NIH Reproduction, Andrology, Gynecology Study Section (2004 - 2008)
- FDA Advisory Committee Obstetrics and Gynecology Devices Panel (2001 - 2005)
- Kotlyar AM, Simsek B, Seifer DB. Disparities in ART Live Birth and Cumulative Live Birth Outcomes for Hispanic and Asian Women Compared to White Non-Hispanic Women Journal Of Clinical Medicine 2021, 10: 2615. PMID: 34198545, PMCID: PMC8231797, DOI: 10.3390/jcm10122615.
- Glenn TL, Kotlyar AM, Seifer DB. The Impact of Intracytoplasmic Sperm Injection in Non-Male Factor Infertility—A Critical Review Journal Of Clinical Medicine 2021, 10: 2616. PMID: 34198564, PMCID: PMC8231975, DOI: 10.3390/jcm10122616.
- Seifer DB, Petok WD, Agrawal A, Glenn TL, Bayer AH, Witt BR, Burgin BD, Lieman HJ. Correction to: Psychological experience and coping strategies of patients in the Northeast US delaying care for infertility during the COVID-19 pandemic Reproductive Biology And Endocrinology 2021, 19: 66. PMID: 33910567, PMCID: PMC8079515, DOI: 10.1186/s12958-021-00746-9.
- Tal R, Seifer DB, Tal R, Granger E, Wantman E, Tal O. AMH Highly Correlates With Cumulative Live Birth Rate in Women with Diminished Ovarian Reserve Independent of Age. The Journal Of Clinical Endocrinology & Metabolism 2021, 106: 2754-2766. PMID: 33729496, DOI: 10.1210/clinem/dgab168.
- Seifer DB. Connecting the dots between oocyte quantity and quality in diminished ovarian reserve Fertility And Sterility 2021, 115: 890. PMID: 33750616, DOI: 10.1016/j.fertnstert.2021.01.020.
- Seifer DB, Petok WD, Agrawal A, Glenn TL, Bayer AH, Witt BR, Burgin BD, Lieman HJ. Psychological experience and coping strategies of patients in the Northeast US delaying care for infertility during the COVID-19 pandemic Reproductive Biology And Endocrinology 2021, 19: 28. PMID: 33618732, PMCID: PMC7899935, DOI: 10.1186/s12958-021-00721-4.
- Kotlyar AM, Seifer DB. Ethnicity/Race and Age-Specific Variations of Serum AMH in Women—A Review Frontiers In Endocrinology 2021, 11: 593216. PMID: 33633682, PMCID: PMC7900163, DOI: 10.3389/fendo.2020.593216.
- Miscarriage determination in first trimester based on alpha-fetoprotein extracted from sanitary padsMor A, Gardezi M, Jubanyik K, Simsek B, Seifer DB, Patrizio P, Esencan E, Imamoglu G, Zhang M, Nichols-Burns SM, Taylor HS. Miscarriage determination in first trimester based on alpha-fetoprotein extracted from sanitary pads Fertility And Sterility 2021, 116: 462-469. PMID: 33461753, DOI: 10.1016/j.fertnstert.2020.10.006.
- Seifer DB, Simsek B, Wantman E, Kotlyar AM. Correction to: Status of racial disparities between black and white women undergoing assisted reproductive technology in the US Reproductive Biology And Endocrinology 2020, 18: 125. PMID: 33349258, PMCID: PMC7751097, DOI: 10.1186/s12958-020-00683-z.
- Simpson S, Seifer DB, Shabanova V, Lynn AY, Howe C, Rowe E, Caprio S, Vash-Margita A. The association between anti-Müllerian hormone and vitamin 25(OH)D serum levels and polycystic ovarian syndrome in adolescent females Reproductive Biology And Endocrinology 2020, 18: 118. PMID: 33218348, PMCID: PMC7679991, DOI: 10.1186/s12958-020-00676-y.
- Kotlyar A, Seifer DB. Anti-Müllerian hormone as a qualitative marker - or just quantity? Current Opinion In Obstetrics & Gynecology 2020, 32: 219-226. PMID: 32205525, DOI: 10.1097/gco.0000000000000623.
- Zagadailov P, Seifer DB, Shan H, Zarek SM, Hsu AL. Do state insurance mandates alter ICSI utilization? Reproductive Biology And Endocrinology 2020, 18: 33. PMID: 32334609, PMCID: PMC7183130, DOI: 10.1186/s12958-020-00589-w.
- Tal R, Seifer CM, Khanimov M, Seifer DB, Tal O. High serum Antimullerian hormone levels are associated with lower live birth rates in women with polycystic ovarian syndrome undergoing assisted reproductive technology Reproductive Biology And Endocrinology 2020, 18: 20. PMID: 32156287, PMCID: PMC7065318, DOI: 10.1186/s12958-020-00581-4.
- Seifer DB, Kallen AN. A counterintuitive lesson in family planning? Patience first: taking a “gap year” after live birth from assisted reproductive technology before frozen embryo transfer is performed Fertility And Sterility 2019, 111: 1109-1110. PMID: 31056317, DOI: 10.1016/j.fertnstert.2019.03.017.
- Xu J, Lawson MS, Xu F, Du Y, Tkachenko OY, Bishop CV, Pejovic-Nezhat L, Seifer DB, Hennebold JD. Vitamin D3 Regulates Follicular Development and Intrafollicular Vitamin D Biosynthesis and Signaling in the Primate Ovary Frontiers In Physiology 2018, 09: 1600. PMID: 30487754, PMCID: PMC6246691, DOI: 10.3389/fphys.2018.01600.
- Seifer DB, Wantman E, Sparks AE, Luke B, Doody KJ, Toner JP, van Voorhis BJ, Lin PC, Reindollar RH. National survey of the Society for Assisted Reproductive Technology membership regarding insurance coverage for assisted reproductive technologies Fertility And Sterility 2018, 110: 1081-1088.e1. PMID: 30396552, DOI: 10.1016/j.fertnstert.2018.07.016.
- Seifer DB. Relevance of International Committee for Monitoring Assisted Reproductive Technology (ICMART) Registry report 2011 Fertility And Sterility 2018, 110: 1032-1033. PMID: 30396542, DOI: 10.1016/j.fertnstert.2018.07.011.
- Luke B, Brown MB, Wantman E, Seifer DB, Sparks AT, Lin PC, Doody KJ, Van Voorhis BJ, Spector LG. Risk of prematurity and infant morbidity and mortality by maternal fertility status and plurality Journal Of Assisted Reproduction And Genetics 2018, 36: 121-138. PMID: 30328574, PMCID: PMC6338589, DOI: 10.1007/s10815-018-1333-z.
- Luke B, Brown MB, Wantman E, Baker VL, Doody KJ, Seifer DB, Spector LG. Risk of severe maternal morbidity by maternal fertility status: a US study in 8 states American Journal Of Obstetrics And Gynecology 2018, 220: 195.e1-195.e12. PMID: 30321527, PMCID: PMC9758649, DOI: 10.1016/j.ajog.2018.10.012.
- Butts SF, Seifer DB, Koelper N, Senapati S, Sammel MD, Hoofnagle AN, Kelly A, Krawetz SA, Santoro N, Zhang H, Diamond MP, Legro RS. Vitamin D Deficiency Is Associated With Poor Ovarian Stimulation Outcome in PCOS but Not Unexplained Infertility. The Journal Of Clinical Endocrinology & Metabolism 2018, 104: 369-378. PMID: 30085176, PMCID: PMC6300410, DOI: 10.1210/jc.2018-00750.
- Zagadailov P, Hsu A, Stern JE, Seifer DB. Temporal Differences in Utilization of Intracytoplasmic Sperm Injection Among U.S. Regions Obstetrics And Gynecology 2018, 132: 310-320. PMID: 29995722, DOI: 10.1097/aog.0000000000002730.
- Tal R, Seifer DB, Wantman E, Baker V, Tal O. Antimüllerian hormone as a predictor of live birth following assisted reproduction: an analysis of 85,062 fresh and thawed cycles from the Society for Assisted Reproductive Technology Clinic Outcome Reporting System database for 2012–2013 Fertility And Sterility 2018, 109: 258-265. PMID: 29331235, DOI: 10.1016/j.fertnstert.2017.10.021.
- Kushnir VA, Seifer DB, Barad DH, Sen A, Gleicher N. Potential therapeutic applications of human anti-Müllerian hormone (AMH) analogues in reproductive medicine Journal Of Assisted Reproduction And Genetics 2017, 34: 1105-1113. PMID: 28643088, PMCID: PMC5581791, DOI: 10.1007/s10815-017-0977-4.
- Zagadailov P, Hsu A, Seifer DB, Stern JE. Differences in utilization of Intracytoplasmic sperm injection (ICSI) within human services (HHS) regions and metropolitan megaregions in the U.S. Reproductive Biology And Endocrinology 2017, 15: 45. PMID: 28606175, PMCID: PMC5469007, DOI: 10.1186/s12958-017-0263-4.
- Irani M, Seifer DB, Grazi RV, Irani S, Rosenwaks Z, Tal R. Vitamin D Decreases Serum VEGF Correlating with Clinical Improvement in Vitamin D-Deficient Women with PCOS: A Randomized Placebo-Controlled Trial Nutrients 2017, 9: 334. PMID: 28350328, PMCID: PMC5409673, DOI: 10.3390/nu9040334.
- Tal R, Seifer DB. Ovarian reserve testing: a user’s guide American Journal Of Obstetrics And Gynecology 2017, 217: 129-140. PMID: 28235465, DOI: 10.1016/j.ajog.2017.02.027.
- Xu J, Hennebold JD, Seifer DB. Direct vitamin D3 actions on rhesus macaque follicles in three-dimensional culture: assessment of follicle survival, growth, steroid, and antimüllerian hormone production Fertility And Sterility 2016, 106: 1815-1820.e1. PMID: 27678030, PMCID: PMC5136302, DOI: 10.1016/j.fertnstert.2016.08.037.
- Orvieto R, Seifer DB. Erratum: Biosimilar FSH preparations- are they identical twins or just siblings? Reproductive Biology And Endocrinology 2016, 14: 59. PMID: 27633971, PMCID: PMC5024420, DOI: 10.1186/s12958-016-0194-5.
- Orvieto R, Seifer DB. Biosimilar FSH preparations- are they identical twins or just siblings? Reproductive Biology And Endocrinology 2016, 14: 32. PMID: 27301324, PMCID: PMC4908720, DOI: 10.1186/s12958-016-0167-8.
- Toner JP, Coddington CC, Doody K, Van Voorhis B, Seifer DB, Ball GD, Luke B, Wantman E. Society for Assisted Reproductive Technology and assisted reproductive technology in the United States: a 2016 update Fertility And Sterility 2016, 106: 541-546. PMID: 27301796, DOI: 10.1016/j.fertnstert.2016.05.026.
- Seifer DB, Tal O, Wantman E, Edul P, Baker VL. Prognostic indicators of assisted reproduction technology outcomes of cycles with ultralow serum antimüllerian hormone: a multivariate analysis of over 5,000 autologous cycles from the Society for Assisted Reproductive Technology Clinic Outcome Reporting System database for 2012–2013 Fertility And Sterility 2015, 105: 385-393.e3. PMID: 26515380, DOI: 10.1016/j.fertnstert.2015.10.004.
- Irani M, Seifer DB, Grazi RV, Julka N, Bhatt D, Kalgi B, Irani S, Tal O, Lambert-Messerlian G, Tal R. Vitamin D Supplementation Decreases TGF-β1 Bioavailability in PCOS: A Randomized Placebo-Controlled Trial. The Journal Of Clinical Endocrinology & Metabolism 2015, 100: 4307-14. PMID: 26485217, DOI: 10.1210/jc.2015-2580.
- Fleming R, Seifer DB, Frattarelli JL, Ruman J. Assessing ovarian response: antral follicle count versus anti-Müllerian hormone Reproductive BioMedicine Online 2015, 31: 486-496. PMID: 26283017, DOI: 10.1016/j.rbmo.2015.06.015.
- Seifer DB, Tal R. Personalized prediction of live birth: Are we there yet? Fertility And Sterility 2015, 104: 283-285. PMID: 26049289, DOI: 10.1016/j.fertnstert.2015.05.004.
- Tal R, Seifer DB, Arici A. The Emerging Role of Angiogenic Factor Dysregulation in the Pathogenesis of Polycystic Ovarian Syndrome Seminars In Reproductive Medicine 2015, 33: 195-207. PMID: 26036901, DOI: 10.1055/s-0035-1552582.
- Mor A, Tal R, Haberman S, McCalla S, Irani M, Perlman J, Seifer DB, Minkoff H. Alpha-Fetoprotein as a Tool to Distinguish Amniotic Fluid From Urine, Vaginal Discharge, and Semen Obstetrics And Gynecology 2015, 125: 448-452. PMID: 25569004, DOI: 10.1097/aog.0000000000000635.
- Azhar E, Seifer DB, Melzer K, Ahmed A, Weedon J, Minkoff H. Knowledge of ovarian reserve and reproductive choices Journal Of Assisted Reproduction And Genetics 2015, 32: 409-415. PMID: 25596723, PMCID: PMC4363241, DOI: 10.1007/s10815-014-0415-9.
- Seifer DB, Minkoff H, Merhi Z. Putting ‘family’ back in family planning Human Reproduction 2014, 30: 16-19. PMID: 25406182, DOI: 10.1093/humrep/deu304.
- Tal R, Tal O, Seifer BJ, Seifer DB. Antimüllerian hormone as predictor of implantation and clinical pregnancy after assisted conception: a systematic review and meta-analysis Fertility And Sterility 2014, 103: 119-130.e3. PMID: 25450298, DOI: 10.1016/j.fertnstert.2014.09.041.
- Scherzer R, Bacchetti P, Messerlian G, Goderre J, Maki PM, Seifer DB, Anastos K, Karim R, Greenblatt RM. Impact of CD4+ Lymphocytes and HIV Infection on Anti‐Müllerian Hormone Levels in a Large Cohort of HIV‐infected and HIV‐uninfected Women American Journal Of Reproductive Immunology 2014, 73: 273-284. PMID: 25339186, PMCID: PMC4323676, DOI: 10.1111/aji.12332.
- Seifer DB, Merhi Z. Is AMH a regulator of follicular atresia? Journal Of Assisted Reproduction And Genetics 2014, 31: 1403-1407. PMID: 25193290, PMCID: PMC4389943, DOI: 10.1007/s10815-014-0328-7.
- Tal R, Seifer DB, Grazi RV, Malter HE. Follicular fluid placental growth factor is increased in polycystic ovarian syndrome: correlation with ovarian stimulation Reproductive Biology And Endocrinology 2014, 12: 82. PMID: 25141961, PMCID: PMC4150963, DOI: 10.1186/1477-7827-12-82.
- Butts SF, Owen C, Mainigi M, Senapati S, Seifer DB, Dokras A. Assisted hatching and intracytoplasmic sperm injection are not associated with improved outcomes in assisted reproduction cycles for diminished ovarian reserve: an analysis of cycles in the United States from 2004 to 2011 Fertility And Sterility 2014, 102: 1041-1047.e1. PMID: 25086790, PMCID: PMC4184996, DOI: 10.1016/j.fertnstert.2014.06.043.
- Irani M, Tal R, Seifer DB, Grazi RV. Successful Same-Cycle Blastocyst Transfer following Laparoscopic Ovarian Detorsion: A Report of Two Cases and Literature Review Case Reports In Obstetrics And Gynecology 2014, 2014: 806378. PMID: 24864219, PMCID: PMC4020476, DOI: 10.1155/2014/806378.
- Tal R, Seifer DB, Khanimov M, Malter HE, Grazi RV, Leader B. Characterization of women with elevated antimüllerian hormone levels (AMH): correlation of AMH with polycystic ovarian syndrome phenotypes and assisted reproductive technology outcomes American Journal Of Obstetrics And Gynecology 2014, 211: 59.e1-59.e8. PMID: 24593938, DOI: 10.1016/j.ajog.2014.02.026.
- Irani M, Minkoff H, Seifer DB, Merhi Z. Vitamin D increases serum levels of the soluble receptor for advanced glycation end products in women with PCOS. The Journal Of Clinical Endocrinology & Metabolism 2014, 99: e886-90. PMID: 24606102, DOI: 10.1210/jc.2013-4374.
- Tal R, Seifer DB. Potential Mechanisms for Racial and Ethnic Differences in Antimüllerian Hormone and Ovarian Reserve International Journal Of Endocrinology 2013, 2013: 818912. PMID: 24348557, PMCID: PMC3857838, DOI: 10.1155/2013/818912.
- Tal R, Seifer DB, Grazi RV, Malter HE. Angiopoietin-1 and angiopoietin-2 are altered in polycystic ovarian syndrome (PCOS) during controlled ovarian stimulation Vascular Cell 2013, 5: 18. PMID: 24156373, PMCID: PMC3895756, DOI: 10.1186/2045-824x-5-18.
- Tal R, Seifer DB, Shohat-Tal A, Grazi RV, Malter HE. Transforming growth factor-β1 and its receptor soluble endoglin are altered in polycystic ovary syndrome during controlled ovarian stimulation Fertility And Sterility 2013, 100: 538-543. PMID: 23684116, DOI: 10.1016/j.fertnstert.2013.04.022.
- Toner JP, Seifer DB. But isn't antimüllerian hormone still better than follicle-stimulating hormone? Fertility And Sterility 2013, 99: e21. PMID: 23628108, DOI: 10.1016/j.fertnstert.2013.03.045.
- Toner JP, Seifer DB. Why we may abandon basal follicle-stimulating hormone testing: a sea change in determining ovarian reserve using antimüllerian hormone Fertility And Sterility 2013, 99: 1825-1830. PMID: 23548941, DOI: 10.1016/j.fertnstert.2013.03.001.
- Tal R, Seifer DB, Khanimov M, Schwartz E, Grazi RV, Malter HE. Anti-Müllerian hormone as an independent predictor of twin versus singleton pregnancy in fresh cycles Reproductive BioMedicine Online 2012, 26: 360-367. PMID: 23419793, DOI: 10.1016/j.rbmo.2012.12.002.
- Butts SF, Ratcliffe S, Dokras A, Seifer DB. Diagnosis and treatment of diminished ovarian reserve in assisted reproductive technology cycles of women up to age 40 years: the role of insurance mandates Fertility And Sterility 2012, 99: 382-388.e7. PMID: 23102859, PMCID: PMC3561490, DOI: 10.1016/j.fertnstert.2012.09.026.
- Leader B, Hegde A, Baca Q, Stone K, Lannon B, Seifer DB, Broekmans F, Baker VL. High frequency of discordance between antimüllerian hormone and follicle-stimulating hormone levels in serum from estradiol-confirmed days 2 to 4 of the menstrual cycle from 5,354 women in U.S. fertility centers Fertility And Sterility 2012, 98: 1037-1042. PMID: 22771028, DOI: 10.1016/j.fertnstert.2012.06.006.
- Merhi ZO, Seifer DB, Weedon J, Adeyemi O, Holman S, Anastos K, Golub ET, Young M, Karim R, Greenblatt R, Minkoff H. Circulating vitamin D correlates with serum antimüllerian hormone levels in late-reproductive-aged women: Women's Interagency HIV Study Fertility And Sterility 2012, 98: 228-234. PMID: 22494925, PMCID: PMC3389125, DOI: 10.1016/j.fertnstert.2012.03.029.
- Buyuk E, Seifer DB, Illions E, Grazi RV, Lieman H. Elevated body mass index is associated with lower serum anti-mullerian hormone levels in infertile women with diminished ovarian reserve but not with normal ovarian reserve Fertility And Sterility 2011, 95: 2364-2368. PMID: 21529798, DOI: 10.1016/j.fertnstert.2011.03.081.
- Buyuk E, Seifer DB, Younger J, Grazi RV, Lieman H. Random anti-Müllerian hormone (AMH) is a predictor of ovarian response in women with elevated baseline early follicular follicle-stimulating hormone levels Fertility And Sterility 2011, 95: 2369-2372. PMID: 21497340, DOI: 10.1016/j.fertnstert.2011.03.071.
- Aslam MF, Merhi ZO, Ahmed S, Kuzbari O, Seifer DB, Minkoff H. Changes in plasma müllerian-inhibiting substance and brain-derived neurotrophic factor after chemotherapy in premenopausal women Fertility And Sterility 2011, 95: 1790-1793. PMID: 21075370, PMCID: PMC3047594, DOI: 10.1016/j.fertnstert.2010.10.033.
- Seifer DB. Strategic planning is long overdue and could mitigate long-term complications that result from delayed diagnosis of primary ovarian insufficiency Fertility And Sterility 2011, 95: 1898. PMID: 21444076, DOI: 10.1016/j.fertnstert.2011.03.008.
- Missmer SA, Seifer DB, Jain T. Cultural factors contributing to health care disparities among patients with infertility in Midwestern United States Fertility And Sterility 2011, 95: 1943-1949. PMID: 21420677, DOI: 10.1016/j.fertnstert.2011.02.039.
- Seifer DB, Baker VL, Leader B. Age-specific serum anti-Müllerian hormone values for 17,120 women presenting to fertility centers within the United States Fertility And Sterility 2010, 95: 747-750. PMID: 21074758, DOI: 10.1016/j.fertnstert.2010.10.011.
- Butts SF, Seifer DB. Racial and ethnic differences in reproductive potential across the life cycle Fertility And Sterility 2009, 93: 681-690. PMID: 19939362, DOI: 10.1016/j.fertnstert.2009.10.047.
- Seifer DB, Zackula R, Grainger DA, Report S. Trends of racial disparities in assisted reproductive technology outcomes in black women compared with white women: Society for Assisted Reproductive Technology 1999 and 2000 vs. 2004–2006 Fertility And Sterility 2009, 93: 626-635. PMID: 19368916, DOI: 10.1016/j.fertnstert.2009.02.084.
- Merhi ZO, Minkoff H, Lambert-Messerlian GM, Macura J, Feldman J, Seifer DB. Plasma brain-derived neurotrophic factor in women after bariatric surgery: a pilot study Fertility And Sterility 2008, 91: 1544-1548. PMID: 18950757, DOI: 10.1016/j.fertnstert.2008.09.032.
- Seifer DB, Golub ET, Lambert-Messerlian G, Benning L, Anastos K, Watts DH, Cohen MH, Karim R, Young MA, Minkoff H, Greenblatt RM. Variations in serum müllerian inhibiting substance between white, black, and Hispanic women Fertility And Sterility 2008, 92: 1674-1678. PMID: 18930217, PMCID: PMC3037722, DOI: 10.1016/j.fertnstert.2008.08.110.
- Buyuk E, Seifer DB. Follicular-fluid neurotrophin levels in women undergoing assisted reproductive technology for different etiologies of infertility Fertility And Sterility 2008, 90: 1611-1615. PMID: 18222435, DOI: 10.1016/j.fertnstert.2007.08.085.
- Seifer DB, Frazier LM, Grainger DA. Disparity in assisted reproductive technologies outcomes in black women compared with white women Fertility And Sterility 2007, 90: 1701-1710. PMID: 17980873, DOI: 10.1016/j.fertnstert.2007.08.024.
- Merhi ZO, Minkoff H, Feldman J, Macura J, Rodriguez C, Seifer DB. Relationship of bariatric surgery to Müllerian-inhibiting substance levels Fertility And Sterility 2007, 90: 221-224. PMID: 17727846, DOI: 10.1016/j.fertnstert.2007.05.073.
- Merhi ZO, Messerlian GM, Minkoff H, Eklund EE, Macura J, Feldman J, Rodriguez C, Seifer DB. Comparison of serum and plasma measurements of Müllerian inhibiting substance Fertility And Sterility 2007, 89: 1836-1837. PMID: 17603056, DOI: 10.1016/j.fertnstert.2007.05.041.
- Seifer DB, MacLaughlin DT. Mullerian Inhibiting Substance is an ovarian growth factor of emerging clinical significance Fertility And Sterility 2007, 88: 539-546. PMID: 17559842, DOI: 10.1016/j.fertnstert.2007.02.014.
- Seifer DB, Golub ET, Lambert-Messerlian G, Springer G, Holman S, Moxley M, Cejtin H, Nathwani N, Anastos K, Minkoff H, Greenblatt RM. Biologic markers of ovarian reserve and reproductive aging: application in a cohort study of HIV infection in women Fertility And Sterility 2007, 88: 1645-1652. PMID: 17418155, PMCID: PMC2682326, DOI: 10.1016/j.fertnstert.2007.01.122.
- Finamore PS, Seifer DB, Ananth CV, Leiblum SR. Social concerns of women undergoing infertility treatment Fertility And Sterility 2007, 88: 817-821. PMID: 17418158, DOI: 10.1016/j.fertnstert.2007.01.009.
- Seifer DB, MacLaughlin DT, Cuckle HS. Serum müllerian-inhibiting substance in Down's syndrome pregnancies Human Reproduction 2007, 22: 1017-1020. PMID: 17218369, DOI: 10.1093/humrep/del497.
- Massad LS, Evans CT, Minkoff H, Watts DH, Greenblatt RM, Levine AM, Anastos K, Young M, Seifer DB, Golub E, Cohen M. Effects of HIV Infection and Its Treatment on Self-Reported Menstrual Abnormalities in Women Journal Of Women's Health 2006, 15: 591-598. PMID: 16796486, DOI: 10.1089/jwh.2006.15.591.
- Seifer DB, Feng B, Shelden RM. Immunocytochemical evidence for the presence and location of the neurotrophin–Trk receptor family in adult human preovulatory ovarian follicles American Journal Of Obstetrics And Gynecology 2006, 194: 1129-1134. PMID: 16580310, DOI: 10.1016/j.ajog.2005.12.022.
- Silberstein T, MacLaughlin DT, Shai I, Trimarchi JR, Lambert-Messerlian G, Seifer DB, Keefe DL, Blazar AS. Müllerian inhibiting substance levels at the time of HCG administration in IVF cycles predict both ovarian reserve and embryo morphology Human Reproduction 2005, 21: 159-163. PMID: 16123085, DOI: 10.1093/humrep/dei270.
- Fleming R, Harborne L, MacLaughlin DT, Ling D, Norman J, Sattar N, Seifer DB. Metformin reduces serum müllerian-inhibiting substance levels in women with polycystic ovary syndrome after protracted treatment Fertility And Sterility 2005, 83: 130-136. PMID: 15652898, DOI: 10.1016/j.fertnstert.2004.05.098.
- Hazout A, Bouchard P, Seifer DB, Aussage P, Junca AM, Cohen-Bacrie P. Serum antimüllerian hormone/müllerian-inhibiting substance appears to be a more discriminatory marker of assisted reproductive technology outcome than follicle-stimulating hormone, inhibin B, or estradiol Fertility And Sterility 2004, 82: 1323-1329. PMID: 15533354, DOI: 10.1016/j.fertnstert.2004.03.061.
- Lee HC, Seifer DB, Shelden RM. Impact of retained embryos on the outcome of assisted reproductive technologies Fertility And Sterility 2004, 82: 334-337. PMID: 15302280, DOI: 10.1016/j.fertnstert.2004.01.035.
- Derman SG, Seifer DB. In vitro fertilization in the older patient. Current Women'S Health Reports 2003, 3: 375-83. PMID: 12959695.
- Feng B, Chen S, Shelden RM, Seifer DB. Effect of gonadotropins on brain-derived neurotrophic factor secretion by human follicular cumulus cells Fertility And Sterility 2003, 80: 658-659. PMID: 12969721, DOI: 10.1016/s0015-0282(03)00742-8.
- Ovarian brain-derived neurotrophic factor is present in follicular fluid from normally cycling womenSeifer DB, Lambert-Messerlian G, Schneyer AL. Ovarian brain-derived neurotrophic factor is present in follicular fluid from normally cycling women Fertility And Sterility 2003, 79: 451-452. PMID: 12568867, DOI: 10.1016/s0015-0282(02)04669-1.
- Seifer DB, DeJesus V, Hubbard K. Mitochondrial deletions in luteinized granulosa cells as a function of age in women undergoing in vitro fertilization Fertility And Sterility 2002, 78: 1046-1048. PMID: 12413991, DOI: 10.1016/s0015-0282(02)04214-0.
- Seifer DB, Feng B, Shelden RM, Chen S, Dreyfus CF. Neurotrophin-4/5 and Neurotrophin-3 Are Present within the Human Ovarian Follicle but Appear to Have Different Paracrine/Autocrine Functions The Journal Of Clinical Endocrinology & Metabolism 2002, 87: 4569-4571. PMID: 12364436, DOI: 10.1210/jc.2002-020499.
- Chin KV, Seifer DB, Feng B, Lin Y, Shih WC. DNA microarray analysis of the expression profiles of luteinized granulosa cells as a function of ovarian reserve Fertility And Sterility 2002, 77: 1214-1218. PMID: 12057731, DOI: 10.1016/s0015-0282(02)03114-x.
- Hock DL, Seifer DB, Kontopoulos E, Ananth CV. Practice Patterns Among Board-Certified Reproductive Endocrinologists Regarding High-Order Multiple Gestations Obstetrics And Gynecology 2002, 99: 763-770. PMID: 11978285, DOI: 10.1097/00006250-200205000-00016.
- Seifer DB, MacLaughlin DT, Christian BP, Feng B, Shelden RM. Early follicular serum müllerian-inhibiting substance levels are associated with ovarian response during assisted reproductive technology cycles Fertility And Sterility 2002, 77: 468-471. PMID: 11872196, DOI: 10.1016/s0015-0282(01)03201-0.
- Seifer DB, Feng B, Shelden RM, Chen S, Dreyfus CF. Brain-derived neurotrophic factor: a novel human ovarian follicular protein. The Journal Of Clinical Endocrinology & Metabolism 2002, 87: 655-9. PMID: 11836300, DOI: 10.1210/jcem.87.2.8213.
- Hock DL, Sharafi K, Dagostino L, Kemmann E, Seifer DB. Contribution of diminished ovarian reserve to hypofertility associated with endometriosis. The Journal Of Reproductive Medicine 2001, 46: 7-10. PMID: 11209637.
- Hock DL, Seifer DB. NEW TREATMENTS OF HYPERANDROGENISM AND HIRSUTISM Obstetrics And Gynecology Clinics Of North America 2000, 27: 567-581. PMID: 10958004, DOI: 10.1016/s0889-8545(05)70156-x.
- Graczykowski JW, Seifer DB. Diagnosis of acute and persistent ectopic pregnancy. Clinical Obstetrics & Gynecology 1999, 42: 9-22; quiz 55-6. PMID: 10073295, DOI: 10.1097/00003081-199903000-00005.
- Houmard BS, Seifer DB. Infertility treatment and informed consent: current practices of reproductive endocrinologists. Obstetrics And Gynecology 1999, 93: 252-7. PMID: 9932565, DOI: 10.1016/s0029-7844(98)00389-5.
- Bopp BL, Seifer DB. Oocyte loss and the perimenopause. Clinical Obstetrics & Gynecology 1998, 41: 898-911. PMID: 9917945, DOI: 10.1097/00003081-199812000-00016.
- Seifer DB, Naftolin F. Moving toward an earlier and better understanding of perimenopause. Fertility And Sterility 1998, 69: 387-8. PMID: 9531863, DOI: 10.1016/s0015-0282(97)00564-5.
- Lambert-Messerlian GM, Steinhoff M, Zheng W, Canick JA, Gajewski WH, Seifer DB, Schneyer AL. Multiple Immunoreactive Inhibin Proteins in Serum from Postmenopausal Women with Epithelial Ovarian Cancer Gynecologic Oncology 1997, 65: 512-516. PMID: 9190984, DOI: 10.1006/gyno.1997.4719.
- Haning RV, Seifer DB, Wheeler CA, Frishman GN, Silver H, Pierce DJ. Effects of fetal number and multifetal reduction on length of in vitro fertilization pregnancies. Obstetrics And Gynecology 1996, 87: 964-8. PMID: 8649707, DOI: 10.1016/0029-7844(96)00059-2.
- Seifer DB, Gardiner AC, Lambert-Messerlian G, Schneyer AL. Differential secretion of dimeric inhibin in cultured luteinized granulosa cells as a function of ovarian reserve. The Journal Of Clinical Endocrinology & Metabolism 1996, 81: 736-9. PMID: 8636296, DOI: 10.1210/jcem.81.2.8636296.
- Tallo CP, Vohr B, Oh W, Rubin LP, Seifer DB, Haning RV. Maternal and neonatal morbidity associated with in vitro fertilization The Journal Of Pediatrics 1995, 127: 794-800. PMID: 7472838, DOI: 10.1016/s0022-3476(95)70175-3.
- Seifer DB, Giudice LC, Dsupin BA, Haning RV, Frishman GN, Burger HG. Follicular fluid insulin-like growth factor-I and insulin-like growth factor-II concentrations vary as a function of day 3 serum follicle stimulating hormone. Human Reproduction 1995, 10: 804-6. PMID: 7650124, DOI: 10.1093/oxfordjournals.humrep.a136042.
- Mark HF, Meyers-Seifer CH, Seifer DB, Demoranville BM, Jackson IM. Assessment of sex chromosome composition using fluorescent in situ hybridization as an adjunct to GTG-banding. Annals Of Clinical & Laboratory Science 1995, 25: 402-8. PMID: 7486815.
- Lyons CA, Wheeler CA, Frishman GN, Hackett RJ, Seifer DB, Haning RV. Early and late presentation of the ovarian hyperstimulation syndrome: two distinct entities with different risk factors. Human Reproduction 1994, 9: 792-9. PMID: 7929724, DOI: 10.1093/oxfordjournals.humrep.a138598.
- Cole LA, Kardana A, Seifer DB, Bohler HC. Urine hCG beta-subunit core fragment, a sensitive test for ectopic pregnancy. The Journal Of Clinical Endocrinology & Metabolism 1994, 78: 497-9. PMID: 7508952, DOI: 10.1210/jcem.78.2.7508952.
- Haning RV, Hua JJ, Hackett RJ, Wheeler CA, Frishman GN, Seifer DB, Dahl CA, Burger HG. Dehydroepiandrosterone sulfate and anovulation increase serum inhibin and affect follicular function during administration of gonadotropins. The Journal Of Clinical Endocrinology & Metabolism 1994, 78: 145-9. PMID: 8288697, DOI: 10.1210/jcem.78.1.8288697.
- Seifer DB, Gutmann JN, Grant WD, Kamps CA, DeCherney AH. Comparison of persistent ectopic pregnancy after laparoscopic salpingostomy versus salpingostomy at laparotomy for ectopic pregnancy. Obstetrics And Gynecology 1993, 81: 378-82. PMID: 8437790.
- Seifer DB, MacLaughlin DT, Penzias AS, Behrman HR, Asmundson L, Donahoe PK, Haning RV, Flynn SD. Gonadotropin-releasing hormone agonist-induced differences in granulosa cell cycle kinetics are associated with alterations in follicular fluid müllerian-inhibiting substance and androgen content. The Journal Of Clinical Endocrinology & Metabolism 1993, 76: 711-4. PMID: 8445031, DOI: 10.1210/jcem.76.3.8445031.
- Seifer DB, Honig J, Penzias AS, Lavy G, Nadkarni PM, Jones EE, DeCherney AH, Flynn SD. Flow cytometric analysis of deoxyribonucleic acid in human granulosa cells as a function of chronological age and ovulation induction regimen. The Journal Of Clinical Endocrinology & Metabolism 1992, 75: 636-40. PMID: 1639962, DOI: 10.1210/jcem.75.2.1639962.
- Schwartz LB, Seifer DB. Diagnostic imaging of adnexal masses. A review. The Journal Of Reproductive Medicine 1992, 37: 63-71. PMID: 1548639.
- Seifer DB, Meyers-Seifer CH, Lavy G, Genel M, DeCherney AH, Yang-Feng TL. Laparoscopic adnexectomy in a prepubertal Turner mosaic female with isodicentric Y. Human Reproduction 1991, 6: 566-7. PMID: 1918308, DOI: 10.1093/oxfordjournals.humrep.a137380.
- Hershlag A, Seifer DB, Carcangiu ML, Patton DL, Diamond MP, DeCherney AH. Salpingoscopy: light microscopic and electron microscopic correlations. Obstetrics And Gynecology 1991, 77: 399-405. PMID: 1992407.
- Seifer DB, Gutmann JN, Doyle MB, Jones EE, Diamond MP, DeCherney AH. Persistent ectopic pregnancy following laparoscopic linear salpingostomy. Obstetrics And Gynecology 1990, 76: 1121-5. PMID: 1700350.
- Miller DS, Seifer DB. Endocrinologic aspects of gestational trophoblastic diseases. International Journal Of Fertility 1990, 35: 137-53. PMID: 1973918.
- Seifer DB, Diamond MP, DeCherney AH. An Appraisal of Barrier Agents in the Reduction of Adhesion Formation Following Surgery Journal Of Gynecologic Surgery 1990, 6: 3-10. PMID: 10149754, DOI: 10.1089/gyn.1990.6.3.
- Seifer DB, Henry JB. The impact of technology on the clinical decision making of house staff. New York State Journal Of Medicine 1989, 89: 444-5. PMID: 2779878.
- Seifer DB, Kennedy AW, Webster KD, Vanderbrug Medendorp S, Isakson DG. Outcome of primary cytoreduction surgery for advanced epithelial ovarian carcinoma. Cleveland Clinic Journal Of Medicine 1988, 55: 555-60. PMID: 3228977, DOI: 10.3949/ccjm.55.6.555.
- Adelson MD, Baggish MS, Seifer DB, Cassell SL, Thompson MA. Cytoreduction of ovarian cancer with the Cavitron ultrasonic surgical aspirator. Obstetrics And Gynecology 1988, 72: 140-3. PMID: 3380505.
- Seifer DB, Albright GA. Epidural anesthesia in toxemia of pregnancy. The New England Journal Of Medicine 1986, 314: 582-3. PMID: 3945301, DOI: 10.1056/NEJM198602273140916.
- Catanzarite VA, Bhat N, Seifer DB, Cortina P, Fainstat T. Successful intrauterine pregnancy after unilateral hysterectomy in a patient with uterus didelphys. A case report. The Journal Of Reproductive Medicine 1986, 31: 133-5. PMID: 3959018.
- Lombard CM, Moore MH, Seifer DB. Diagnosis of systemic polyarteritis nodosa following total abdominal hysterectomy and bilateral salpingo-oophorectomy: a case report. International Journal Of Gynecological Pathology : Official Journal Of The International Society Of Gynecological Pathologists 1986, 5: 63-8. PMID: 2870032, DOI: 10.1097/00004347-198603000-00007.
- Seifer DB, Ferguson JE, Behrens CM, Zemel S, Stevenson DK, Ross JC. Nonimmune hydrops fetalis in association with hemangioma of the umbilical cord. Obstetrics And Gynecology 1985, 66: 283-6. PMID: 3895076.
- Seifer DB, Sandberg EC, Ueland K, Sladen RN. Water intoxication and hyponatremic encephalopathy from the use of an oxytocin nasal spray. A case report. The Journal Of Reproductive Medicine 1985, 30: 225-8. PMID: 3923190.
- Kresch AJ, Seifer DB, Sachs LB, Barrese I. Laparoscopy in 100 women with chronic pelvic pain. Obstetrics And Gynecology 1984, 64: 672-4. PMID: 6238250.
- Lewinstein C, Silberman H, Goren G, Feinstein E, Berne TV, Seifer D, Witt R, Gonsier A, Greaney G. Experience with a coaxial dialysis cannula for temporary vascular access. Transactions - American Society For Artificial Internal Organs 1983, 29: 357-9. PMID: 6673252.
Biography
As a reproductive endocrinologist and infertility specialist, David B. Seifer, MD, sees himself as a liaison. His goal is to help his patients choose the right medical approach, while respecting their personal values.
“When I first meet with a couple or an individual, we talk. Over the course of an hour, I get an idea of their world view, how they envision their future and their hopes for a family,” Dr. Seifer says. “I then figure out how to apply the technology we have at our disposal to their individual needs. That might mean egg freezing for women who are concerned about future fertility but aren’t ready to conceive now. We also have egg donor and surrogate options for women of advanced maternal age or for same-sex couples.”
Dr. Seifer says he was drawn to the field of obstetrics and gynecology in medical school. “It was an epiphany when I realized how appreciative patients were,” he says. “To have someone let you into their life during such an important time, and to be able to make an impact, is such a joy.”
The dawn of in vitro fertilization (IVF) was occurring around the time Dr. Seifer completed his medical degree. “There was such excitement, like science fiction becoming a reality,” he says. “It’s a convergence of technology and biology, and I was excited to practice it and help build families.”
Plus, he enjoys working with patients who are as motivated as he is to reach a successful outcome. “Everybody is moving in the same direction,” says Dr. Seifer, who primarily sees patients in Yale Fertility Center’s Orange office, which he describes as a comfortable, calming place. “We take care of everything that may seem daunting in an efficient, relaxed way.”
Dr. Seifer’s research include the mechanisms of reproductive aging. In fact, his research led to a simple blood test used worldwide today that helps determine the health of a woman’s ovaries and a rough estimate of her egg count. He is also president of the Society for Assisted Reproductive Technology, the primary, national organization that sets clinical and laboratory guidelines and standards for safety and quality metrics for the practice of IVF.
Titles
- Professor of Obstetrics, Gynecology & Reproductive Sciences
- Fellowship Director, Reproductive Endocrinology & Infertility
Education & Training
- MDUniversity of Illinois - Chicago, Medicine (1981)
Additional Information
- Ferring Innovation Grant for Racial Equality in Reproductive Medicine and Maternal Health (2021-22): Ferring Pharmaceuticals (2021)
- Connecticut Top Docs: Connecticut Magazine (2021), (2022)
- Prize Paper Awards for SART and ASRM - Co-author: ASRM (2020)
- Prize Paper Award for Health Care Disparities- Co-author: ASRM (2019), (2022)
- Titus Fellowship Award: Yale School of Medicine (2019)
- ASRM Star Award: American Society of Reproductive Medicine (2016), (2017), (2018), (2019), (2020), (2021), (2022)
- America’s Top Doctors Castle Connolly Medical Guide for 12 years: Castle Connolly (2014)
- Thomas Alva Edison Patent Award: Research and Development Council of New Jersey (2011)
- Inventor of the Year Award: New Jersey Inventors Hall of Fame (2011)
- Life Teacher Award: Maimonides Medical Center (2007)
- Society for Assisted Reproductive Technology (SART) (2017 - 2021): President of SART 2017-2018; Member of Presidential and Executive Council of Society for Assisted Reproductive Technology (SART) 2016 - 2021.
- Reproductive Biology and Endocrinology (2016 - Present): Co-Editor-in-Chief
- NICHD – NIH Reproduction, Andrology, Gynecology Study Section (2004 - 2008)
- FDA Advisory Committee Obstetrics and Gynecology Devices Panel (2001 - 2005)
- Kotlyar AM, Simsek B, Seifer DB. Disparities in ART Live Birth and Cumulative Live Birth Outcomes for Hispanic and Asian Women Compared to White Non-Hispanic Women Journal Of Clinical Medicine 2021, 10: 2615. PMID: 34198545, PMCID: PMC8231797, DOI: 10.3390/jcm10122615.
- Glenn TL, Kotlyar AM, Seifer DB. The Impact of Intracytoplasmic Sperm Injection in Non-Male Factor Infertility—A Critical Review Journal Of Clinical Medicine 2021, 10: 2616. PMID: 34198564, PMCID: PMC8231975, DOI: 10.3390/jcm10122616.
- Seifer DB, Petok WD, Agrawal A, Glenn TL, Bayer AH, Witt BR, Burgin BD, Lieman HJ. Correction to: Psychological experience and coping strategies of patients in the Northeast US delaying care for infertility during the COVID-19 pandemic Reproductive Biology And Endocrinology 2021, 19: 66. PMID: 33910567, PMCID: PMC8079515, DOI: 10.1186/s12958-021-00746-9.
- Tal R, Seifer DB, Tal R, Granger E, Wantman E, Tal O. AMH Highly Correlates With Cumulative Live Birth Rate in Women with Diminished Ovarian Reserve Independent of Age. The Journal Of Clinical Endocrinology & Metabolism 2021, 106: 2754-2766. PMID: 33729496, DOI: 10.1210/clinem/dgab168.
- Seifer DB. Connecting the dots between oocyte quantity and quality in diminished ovarian reserve Fertility And Sterility 2021, 115: 890. PMID: 33750616, DOI: 10.1016/j.fertnstert.2021.01.020.
- Seifer DB, Petok WD, Agrawal A, Glenn TL, Bayer AH, Witt BR, Burgin BD, Lieman HJ. Psychological experience and coping strategies of patients in the Northeast US delaying care for infertility during the COVID-19 pandemic Reproductive Biology And Endocrinology 2021, 19: 28. PMID: 33618732, PMCID: PMC7899935, DOI: 10.1186/s12958-021-00721-4.
- Kotlyar AM, Seifer DB. Ethnicity/Race and Age-Specific Variations of Serum AMH in Women—A Review Frontiers In Endocrinology 2021, 11: 593216. PMID: 33633682, PMCID: PMC7900163, DOI: 10.3389/fendo.2020.593216.
- Miscarriage determination in first trimester based on alpha-fetoprotein extracted from sanitary padsMor A, Gardezi M, Jubanyik K, Simsek B, Seifer DB, Patrizio P, Esencan E, Imamoglu G, Zhang M, Nichols-Burns SM, Taylor HS. Miscarriage determination in first trimester based on alpha-fetoprotein extracted from sanitary pads Fertility And Sterility 2021, 116: 462-469. PMID: 33461753, DOI: 10.1016/j.fertnstert.2020.10.006.
- Seifer DB, Simsek B, Wantman E, Kotlyar AM. Correction to: Status of racial disparities between black and white women undergoing assisted reproductive technology in the US Reproductive Biology And Endocrinology 2020, 18: 125. PMID: 33349258, PMCID: PMC7751097, DOI: 10.1186/s12958-020-00683-z.
- Simpson S, Seifer DB, Shabanova V, Lynn AY, Howe C, Rowe E, Caprio S, Vash-Margita A. The association between anti-Müllerian hormone and vitamin 25(OH)D serum levels and polycystic ovarian syndrome in adolescent females Reproductive Biology And Endocrinology 2020, 18: 118. PMID: 33218348, PMCID: PMC7679991, DOI: 10.1186/s12958-020-00676-y.
- Kotlyar A, Seifer DB. Anti-Müllerian hormone as a qualitative marker - or just quantity? Current Opinion In Obstetrics & Gynecology 2020, 32: 219-226. PMID: 32205525, DOI: 10.1097/gco.0000000000000623.
- Zagadailov P, Seifer DB, Shan H, Zarek SM, Hsu AL. Do state insurance mandates alter ICSI utilization? Reproductive Biology And Endocrinology 2020, 18: 33. PMID: 32334609, PMCID: PMC7183130, DOI: 10.1186/s12958-020-00589-w.
- Tal R, Seifer CM, Khanimov M, Seifer DB, Tal O. High serum Antimullerian hormone levels are associated with lower live birth rates in women with polycystic ovarian syndrome undergoing assisted reproductive technology Reproductive Biology And Endocrinology 2020, 18: 20. PMID: 32156287, PMCID: PMC7065318, DOI: 10.1186/s12958-020-00581-4.
- Seifer DB, Kallen AN. A counterintuitive lesson in family planning? Patience first: taking a “gap year” after live birth from assisted reproductive technology before frozen embryo transfer is performed Fertility And Sterility 2019, 111: 1109-1110. PMID: 31056317, DOI: 10.1016/j.fertnstert.2019.03.017.
- Xu J, Lawson MS, Xu F, Du Y, Tkachenko OY, Bishop CV, Pejovic-Nezhat L, Seifer DB, Hennebold JD. Vitamin D3 Regulates Follicular Development and Intrafollicular Vitamin D Biosynthesis and Signaling in the Primate Ovary Frontiers In Physiology 2018, 09: 1600. PMID: 30487754, PMCID: PMC6246691, DOI: 10.3389/fphys.2018.01600.
- Seifer DB, Wantman E, Sparks AE, Luke B, Doody KJ, Toner JP, van Voorhis BJ, Lin PC, Reindollar RH. National survey of the Society for Assisted Reproductive Technology membership regarding insurance coverage for assisted reproductive technologies Fertility And Sterility 2018, 110: 1081-1088.e1. PMID: 30396552, DOI: 10.1016/j.fertnstert.2018.07.016.
- Seifer DB. Relevance of International Committee for Monitoring Assisted Reproductive Technology (ICMART) Registry report 2011 Fertility And Sterility 2018, 110: 1032-1033. PMID: 30396542, DOI: 10.1016/j.fertnstert.2018.07.011.
- Luke B, Brown MB, Wantman E, Seifer DB, Sparks AT, Lin PC, Doody KJ, Van Voorhis BJ, Spector LG. Risk of prematurity and infant morbidity and mortality by maternal fertility status and plurality Journal Of Assisted Reproduction And Genetics 2018, 36: 121-138. PMID: 30328574, PMCID: PMC6338589, DOI: 10.1007/s10815-018-1333-z.
- Luke B, Brown MB, Wantman E, Baker VL, Doody KJ, Seifer DB, Spector LG. Risk of severe maternal morbidity by maternal fertility status: a US study in 8 states American Journal Of Obstetrics And Gynecology 2018, 220: 195.e1-195.e12. PMID: 30321527, PMCID: PMC9758649, DOI: 10.1016/j.ajog.2018.10.012.
- Butts SF, Seifer DB, Koelper N, Senapati S, Sammel MD, Hoofnagle AN, Kelly A, Krawetz SA, Santoro N, Zhang H, Diamond MP, Legro RS. Vitamin D Deficiency Is Associated With Poor Ovarian Stimulation Outcome in PCOS but Not Unexplained Infertility. The Journal Of Clinical Endocrinology & Metabolism 2018, 104: 369-378. PMID: 30085176, PMCID: PMC6300410, DOI: 10.1210/jc.2018-00750.
- Zagadailov P, Hsu A, Stern JE, Seifer DB. Temporal Differences in Utilization of Intracytoplasmic Sperm Injection Among U.S. Regions Obstetrics And Gynecology 2018, 132: 310-320. PMID: 29995722, DOI: 10.1097/aog.0000000000002730.
- Tal R, Seifer DB, Wantman E, Baker V, Tal O. Antimüllerian hormone as a predictor of live birth following assisted reproduction: an analysis of 85,062 fresh and thawed cycles from the Society for Assisted Reproductive Technology Clinic Outcome Reporting System database for 2012–2013 Fertility And Sterility 2018, 109: 258-265. PMID: 29331235, DOI: 10.1016/j.fertnstert.2017.10.021.
- Kushnir VA, Seifer DB, Barad DH, Sen A, Gleicher N. Potential therapeutic applications of human anti-Müllerian hormone (AMH) analogues in reproductive medicine Journal Of Assisted Reproduction And Genetics 2017, 34: 1105-1113. PMID: 28643088, PMCID: PMC5581791, DOI: 10.1007/s10815-017-0977-4.
- Zagadailov P, Hsu A, Seifer DB, Stern JE. Differences in utilization of Intracytoplasmic sperm injection (ICSI) within human services (HHS) regions and metropolitan megaregions in the U.S. Reproductive Biology And Endocrinology 2017, 15: 45. PMID: 28606175, PMCID: PMC5469007, DOI: 10.1186/s12958-017-0263-4.
- Irani M, Seifer DB, Grazi RV, Irani S, Rosenwaks Z, Tal R. Vitamin D Decreases Serum VEGF Correlating with Clinical Improvement in Vitamin D-Deficient Women with PCOS: A Randomized Placebo-Controlled Trial Nutrients 2017, 9: 334. PMID: 28350328, PMCID: PMC5409673, DOI: 10.3390/nu9040334.
- Tal R, Seifer DB. Ovarian reserve testing: a user’s guide American Journal Of Obstetrics And Gynecology 2017, 217: 129-140. PMID: 28235465, DOI: 10.1016/j.ajog.2017.02.027.
- Xu J, Hennebold JD, Seifer DB. Direct vitamin D3 actions on rhesus macaque follicles in three-dimensional culture: assessment of follicle survival, growth, steroid, and antimüllerian hormone production Fertility And Sterility 2016, 106: 1815-1820.e1. PMID: 27678030, PMCID: PMC5136302, DOI: 10.1016/j.fertnstert.2016.08.037.
- Orvieto R, Seifer DB. Erratum: Biosimilar FSH preparations- are they identical twins or just siblings? Reproductive Biology And Endocrinology 2016, 14: 59. PMID: 27633971, PMCID: PMC5024420, DOI: 10.1186/s12958-016-0194-5.
- Orvieto R, Seifer DB. Biosimilar FSH preparations- are they identical twins or just siblings? Reproductive Biology And Endocrinology 2016, 14: 32. PMID: 27301324, PMCID: PMC4908720, DOI: 10.1186/s12958-016-0167-8.
- Toner JP, Coddington CC, Doody K, Van Voorhis B, Seifer DB, Ball GD, Luke B, Wantman E. Society for Assisted Reproductive Technology and assisted reproductive technology in the United States: a 2016 update Fertility And Sterility 2016, 106: 541-546. PMID: 27301796, DOI: 10.1016/j.fertnstert.2016.05.026.
- Seifer DB, Tal O, Wantman E, Edul P, Baker VL. Prognostic indicators of assisted reproduction technology outcomes of cycles with ultralow serum antimüllerian hormone: a multivariate analysis of over 5,000 autologous cycles from the Society for Assisted Reproductive Technology Clinic Outcome Reporting System database for 2012–2013 Fertility And Sterility 2015, 105: 385-393.e3. PMID: 26515380, DOI: 10.1016/j.fertnstert.2015.10.004.
- Irani M, Seifer DB, Grazi RV, Julka N, Bhatt D, Kalgi B, Irani S, Tal O, Lambert-Messerlian G, Tal R. Vitamin D Supplementation Decreases TGF-β1 Bioavailability in PCOS: A Randomized Placebo-Controlled Trial. The Journal Of Clinical Endocrinology & Metabolism 2015, 100: 4307-14. PMID: 26485217, DOI: 10.1210/jc.2015-2580.
- Fleming R, Seifer DB, Frattarelli JL, Ruman J. Assessing ovarian response: antral follicle count versus anti-Müllerian hormone Reproductive BioMedicine Online 2015, 31: 486-496. PMID: 26283017, DOI: 10.1016/j.rbmo.2015.06.015.
- Seifer DB, Tal R. Personalized prediction of live birth: Are we there yet? Fertility And Sterility 2015, 104: 283-285. PMID: 26049289, DOI: 10.1016/j.fertnstert.2015.05.004.
- Tal R, Seifer DB, Arici A. The Emerging Role of Angiogenic Factor Dysregulation in the Pathogenesis of Polycystic Ovarian Syndrome Seminars In Reproductive Medicine 2015, 33: 195-207. PMID: 26036901, DOI: 10.1055/s-0035-1552582.
- Mor A, Tal R, Haberman S, McCalla S, Irani M, Perlman J, Seifer DB, Minkoff H. Alpha-Fetoprotein as a Tool to Distinguish Amniotic Fluid From Urine, Vaginal Discharge, and Semen Obstetrics And Gynecology 2015, 125: 448-452. PMID: 25569004, DOI: 10.1097/aog.0000000000000635.
- Azhar E, Seifer DB, Melzer K, Ahmed A, Weedon J, Minkoff H. Knowledge of ovarian reserve and reproductive choices Journal Of Assisted Reproduction And Genetics 2015, 32: 409-415. PMID: 25596723, PMCID: PMC4363241, DOI: 10.1007/s10815-014-0415-9.
- Seifer DB, Minkoff H, Merhi Z. Putting ‘family’ back in family planning Human Reproduction 2014, 30: 16-19. PMID: 25406182, DOI: 10.1093/humrep/deu304.
- Tal R, Tal O, Seifer BJ, Seifer DB. Antimüllerian hormone as predictor of implantation and clinical pregnancy after assisted conception: a systematic review and meta-analysis Fertility And Sterility 2014, 103: 119-130.e3. PMID: 25450298, DOI: 10.1016/j.fertnstert.2014.09.041.
- Scherzer R, Bacchetti P, Messerlian G, Goderre J, Maki PM, Seifer DB, Anastos K, Karim R, Greenblatt RM. Impact of CD4+ Lymphocytes and HIV Infection on Anti‐Müllerian Hormone Levels in a Large Cohort of HIV‐infected and HIV‐uninfected Women American Journal Of Reproductive Immunology 2014, 73: 273-284. PMID: 25339186, PMCID: PMC4323676, DOI: 10.1111/aji.12332.
- Seifer DB, Merhi Z. Is AMH a regulator of follicular atresia? Journal Of Assisted Reproduction And Genetics 2014, 31: 1403-1407. PMID: 25193290, PMCID: PMC4389943, DOI: 10.1007/s10815-014-0328-7.
- Tal R, Seifer DB, Grazi RV, Malter HE. Follicular fluid placental growth factor is increased in polycystic ovarian syndrome: correlation with ovarian stimulation Reproductive Biology And Endocrinology 2014, 12: 82. PMID: 25141961, PMCID: PMC4150963, DOI: 10.1186/1477-7827-12-82.
- Butts SF, Owen C, Mainigi M, Senapati S, Seifer DB, Dokras A. Assisted hatching and intracytoplasmic sperm injection are not associated with improved outcomes in assisted reproduction cycles for diminished ovarian reserve: an analysis of cycles in the United States from 2004 to 2011 Fertility And Sterility 2014, 102: 1041-1047.e1. PMID: 25086790, PMCID: PMC4184996, DOI: 10.1016/j.fertnstert.2014.06.043.
- Irani M, Tal R, Seifer DB, Grazi RV. Successful Same-Cycle Blastocyst Transfer following Laparoscopic Ovarian Detorsion: A Report of Two Cases and Literature Review Case Reports In Obstetrics And Gynecology 2014, 2014: 806378. PMID: 24864219, PMCID: PMC4020476, DOI: 10.1155/2014/806378.
- Tal R, Seifer DB, Khanimov M, Malter HE, Grazi RV, Leader B. Characterization of women with elevated antimüllerian hormone levels (AMH): correlation of AMH with polycystic ovarian syndrome phenotypes and assisted reproductive technology outcomes American Journal Of Obstetrics And Gynecology 2014, 211: 59.e1-59.e8. PMID: 24593938, DOI: 10.1016/j.ajog.2014.02.026.
- Irani M, Minkoff H, Seifer DB, Merhi Z. Vitamin D increases serum levels of the soluble receptor for advanced glycation end products in women with PCOS. The Journal Of Clinical Endocrinology & Metabolism 2014, 99: e886-90. PMID: 24606102, DOI: 10.1210/jc.2013-4374.
- Tal R, Seifer DB. Potential Mechanisms for Racial and Ethnic Differences in Antimüllerian Hormone and Ovarian Reserve International Journal Of Endocrinology 2013, 2013: 818912. PMID: 24348557, PMCID: PMC3857838, DOI: 10.1155/2013/818912.
- Tal R, Seifer DB, Grazi RV, Malter HE. Angiopoietin-1 and angiopoietin-2 are altered in polycystic ovarian syndrome (PCOS) during controlled ovarian stimulation Vascular Cell 2013, 5: 18. PMID: 24156373, PMCID: PMC3895756, DOI: 10.1186/2045-824x-5-18.
- Tal R, Seifer DB, Shohat-Tal A, Grazi RV, Malter HE. Transforming growth factor-β1 and its receptor soluble endoglin are altered in polycystic ovary syndrome during controlled ovarian stimulation Fertility And Sterility 2013, 100: 538-543. PMID: 23684116, DOI: 10.1016/j.fertnstert.2013.04.022.
- Toner JP, Seifer DB. But isn't antimüllerian hormone still better than follicle-stimulating hormone? Fertility And Sterility 2013, 99: e21. PMID: 23628108, DOI: 10.1016/j.fertnstert.2013.03.045.
- Toner JP, Seifer DB. Why we may abandon basal follicle-stimulating hormone testing: a sea change in determining ovarian reserve using antimüllerian hormone Fertility And Sterility 2013, 99: 1825-1830. PMID: 23548941, DOI: 10.1016/j.fertnstert.2013.03.001.
- Tal R, Seifer DB, Khanimov M, Schwartz E, Grazi RV, Malter HE. Anti-Müllerian hormone as an independent predictor of twin versus singleton pregnancy in fresh cycles Reproductive BioMedicine Online 2012, 26: 360-367. PMID: 23419793, DOI: 10.1016/j.rbmo.2012.12.002.
- Butts SF, Ratcliffe S, Dokras A, Seifer DB. Diagnosis and treatment of diminished ovarian reserve in assisted reproductive technology cycles of women up to age 40 years: the role of insurance mandates Fertility And Sterility 2012, 99: 382-388.e7. PMID: 23102859, PMCID: PMC3561490, DOI: 10.1016/j.fertnstert.2012.09.026.
- Leader B, Hegde A, Baca Q, Stone K, Lannon B, Seifer DB, Broekmans F, Baker VL. High frequency of discordance between antimüllerian hormone and follicle-stimulating hormone levels in serum from estradiol-confirmed days 2 to 4 of the menstrual cycle from 5,354 women in U.S. fertility centers Fertility And Sterility 2012, 98: 1037-1042. PMID: 22771028, DOI: 10.1016/j.fertnstert.2012.06.006.
- Merhi ZO, Seifer DB, Weedon J, Adeyemi O, Holman S, Anastos K, Golub ET, Young M, Karim R, Greenblatt R, Minkoff H. Circulating vitamin D correlates with serum antimüllerian hormone levels in late-reproductive-aged women: Women's Interagency HIV Study Fertility And Sterility 2012, 98: 228-234. PMID: 22494925, PMCID: PMC3389125, DOI: 10.1016/j.fertnstert.2012.03.029.
- Buyuk E, Seifer DB, Illions E, Grazi RV, Lieman H. Elevated body mass index is associated with lower serum anti-mullerian hormone levels in infertile women with diminished ovarian reserve but not with normal ovarian reserve Fertility And Sterility 2011, 95: 2364-2368. PMID: 21529798, DOI: 10.1016/j.fertnstert.2011.03.081.
- Buyuk E, Seifer DB, Younger J, Grazi RV, Lieman H. Random anti-Müllerian hormone (AMH) is a predictor of ovarian response in women with elevated baseline early follicular follicle-stimulating hormone levels Fertility And Sterility 2011, 95: 2369-2372. PMID: 21497340, DOI: 10.1016/j.fertnstert.2011.03.071.
- Aslam MF, Merhi ZO, Ahmed S, Kuzbari O, Seifer DB, Minkoff H. Changes in plasma müllerian-inhibiting substance and brain-derived neurotrophic factor after chemotherapy in premenopausal women Fertility And Sterility 2011, 95: 1790-1793. PMID: 21075370, PMCID: PMC3047594, DOI: 10.1016/j.fertnstert.2010.10.033.
- Seifer DB. Strategic planning is long overdue and could mitigate long-term complications that result from delayed diagnosis of primary ovarian insufficiency Fertility And Sterility 2011, 95: 1898. PMID: 21444076, DOI: 10.1016/j.fertnstert.2011.03.008.
- Missmer SA, Seifer DB, Jain T. Cultural factors contributing to health care disparities among patients with infertility in Midwestern United States Fertility And Sterility 2011, 95: 1943-1949. PMID: 21420677, DOI: 10.1016/j.fertnstert.2011.02.039.
- Seifer DB, Baker VL, Leader B. Age-specific serum anti-Müllerian hormone values for 17,120 women presenting to fertility centers within the United States Fertility And Sterility 2010, 95: 747-750. PMID: 21074758, DOI: 10.1016/j.fertnstert.2010.10.011.
- Butts SF, Seifer DB. Racial and ethnic differences in reproductive potential across the life cycle Fertility And Sterility 2009, 93: 681-690. PMID: 19939362, DOI: 10.1016/j.fertnstert.2009.10.047.
- Seifer DB, Zackula R, Grainger DA, Report S. Trends of racial disparities in assisted reproductive technology outcomes in black women compared with white women: Society for Assisted Reproductive Technology 1999 and 2000 vs. 2004–2006 Fertility And Sterility 2009, 93: 626-635. PMID: 19368916, DOI: 10.1016/j.fertnstert.2009.02.084.
- Merhi ZO, Minkoff H, Lambert-Messerlian GM, Macura J, Feldman J, Seifer DB. Plasma brain-derived neurotrophic factor in women after bariatric surgery: a pilot study Fertility And Sterility 2008, 91: 1544-1548. PMID: 18950757, DOI: 10.1016/j.fertnstert.2008.09.032.
- Seifer DB, Golub ET, Lambert-Messerlian G, Benning L, Anastos K, Watts DH, Cohen MH, Karim R, Young MA, Minkoff H, Greenblatt RM. Variations in serum müllerian inhibiting substance between white, black, and Hispanic women Fertility And Sterility 2008, 92: 1674-1678. PMID: 18930217, PMCID: PMC3037722, DOI: 10.1016/j.fertnstert.2008.08.110.
- Buyuk E, Seifer DB. Follicular-fluid neurotrophin levels in women undergoing assisted reproductive technology for different etiologies of infertility Fertility And Sterility 2008, 90: 1611-1615. PMID: 18222435, DOI: 10.1016/j.fertnstert.2007.08.085.
- Seifer DB, Frazier LM, Grainger DA. Disparity in assisted reproductive technologies outcomes in black women compared with white women Fertility And Sterility 2007, 90: 1701-1710. PMID: 17980873, DOI: 10.1016/j.fertnstert.2007.08.024.
- Merhi ZO, Minkoff H, Feldman J, Macura J, Rodriguez C, Seifer DB. Relationship of bariatric surgery to Müllerian-inhibiting substance levels Fertility And Sterility 2007, 90: 221-224. PMID: 17727846, DOI: 10.1016/j.fertnstert.2007.05.073.
- Merhi ZO, Messerlian GM, Minkoff H, Eklund EE, Macura J, Feldman J, Rodriguez C, Seifer DB. Comparison of serum and plasma measurements of Müllerian inhibiting substance Fertility And Sterility 2007, 89: 1836-1837. PMID: 17603056, DOI: 10.1016/j.fertnstert.2007.05.041.
- Seifer DB, MacLaughlin DT. Mullerian Inhibiting Substance is an ovarian growth factor of emerging clinical significance Fertility And Sterility 2007, 88: 539-546. PMID: 17559842, DOI: 10.1016/j.fertnstert.2007.02.014.
- Seifer DB, Golub ET, Lambert-Messerlian G, Springer G, Holman S, Moxley M, Cejtin H, Nathwani N, Anastos K, Minkoff H, Greenblatt RM. Biologic markers of ovarian reserve and reproductive aging: application in a cohort study of HIV infection in women Fertility And Sterility 2007, 88: 1645-1652. PMID: 17418155, PMCID: PMC2682326, DOI: 10.1016/j.fertnstert.2007.01.122.
- Finamore PS, Seifer DB, Ananth CV, Leiblum SR. Social concerns of women undergoing infertility treatment Fertility And Sterility 2007, 88: 817-821. PMID: 17418158, DOI: 10.1016/j.fertnstert.2007.01.009.
- Seifer DB, MacLaughlin DT, Cuckle HS. Serum müllerian-inhibiting substance in Down's syndrome pregnancies Human Reproduction 2007, 22: 1017-1020. PMID: 17218369, DOI: 10.1093/humrep/del497.
- Massad LS, Evans CT, Minkoff H, Watts DH, Greenblatt RM, Levine AM, Anastos K, Young M, Seifer DB, Golub E, Cohen M. Effects of HIV Infection and Its Treatment on Self-Reported Menstrual Abnormalities in Women Journal Of Women's Health 2006, 15: 591-598. PMID: 16796486, DOI: 10.1089/jwh.2006.15.591.
- Seifer DB, Feng B, Shelden RM. Immunocytochemical evidence for the presence and location of the neurotrophin–Trk receptor family in adult human preovulatory ovarian follicles American Journal Of Obstetrics And Gynecology 2006, 194: 1129-1134. PMID: 16580310, DOI: 10.1016/j.ajog.2005.12.022.
- Silberstein T, MacLaughlin DT, Shai I, Trimarchi JR, Lambert-Messerlian G, Seifer DB, Keefe DL, Blazar AS. Müllerian inhibiting substance levels at the time of HCG administration in IVF cycles predict both ovarian reserve and embryo morphology Human Reproduction 2005, 21: 159-163. PMID: 16123085, DOI: 10.1093/humrep/dei270.
- Fleming R, Harborne L, MacLaughlin DT, Ling D, Norman J, Sattar N, Seifer DB. Metformin reduces serum müllerian-inhibiting substance levels in women with polycystic ovary syndrome after protracted treatment Fertility And Sterility 2005, 83: 130-136. PMID: 15652898, DOI: 10.1016/j.fertnstert.2004.05.098.
- Hazout A, Bouchard P, Seifer DB, Aussage P, Junca AM, Cohen-Bacrie P. Serum antimüllerian hormone/müllerian-inhibiting substance appears to be a more discriminatory marker of assisted reproductive technology outcome than follicle-stimulating hormone, inhibin B, or estradiol Fertility And Sterility 2004, 82: 1323-1329. PMID: 15533354, DOI: 10.1016/j.fertnstert.2004.03.061.
- Lee HC, Seifer DB, Shelden RM. Impact of retained embryos on the outcome of assisted reproductive technologies Fertility And Sterility 2004, 82: 334-337. PMID: 15302280, DOI: 10.1016/j.fertnstert.2004.01.035.
- Derman SG, Seifer DB. In vitro fertilization in the older patient. Current Women'S Health Reports 2003, 3: 375-83. PMID: 12959695.
- Feng B, Chen S, Shelden RM, Seifer DB. Effect of gonadotropins on brain-derived neurotrophic factor secretion by human follicular cumulus cells Fertility And Sterility 2003, 80: 658-659. PMID: 12969721, DOI: 10.1016/s0015-0282(03)00742-8.
- Ovarian brain-derived neurotrophic factor is present in follicular fluid from normally cycling womenSeifer DB, Lambert-Messerlian G, Schneyer AL. Ovarian brain-derived neurotrophic factor is present in follicular fluid from normally cycling women Fertility And Sterility 2003, 79: 451-452. PMID: 12568867, DOI: 10.1016/s0015-0282(02)04669-1.
- Seifer DB, DeJesus V, Hubbard K. Mitochondrial deletions in luteinized granulosa cells as a function of age in women undergoing in vitro fertilization Fertility And Sterility 2002, 78: 1046-1048. PMID: 12413991, DOI: 10.1016/s0015-0282(02)04214-0.
- Seifer DB, Feng B, Shelden RM, Chen S, Dreyfus CF. Neurotrophin-4/5 and Neurotrophin-3 Are Present within the Human Ovarian Follicle but Appear to Have Different Paracrine/Autocrine Functions The Journal Of Clinical Endocrinology & Metabolism 2002, 87: 4569-4571. PMID: 12364436, DOI: 10.1210/jc.2002-020499.
- Chin KV, Seifer DB, Feng B, Lin Y, Shih WC. DNA microarray analysis of the expression profiles of luteinized granulosa cells as a function of ovarian reserve Fertility And Sterility 2002, 77: 1214-1218. PMID: 12057731, DOI: 10.1016/s0015-0282(02)03114-x.
- Hock DL, Seifer DB, Kontopoulos E, Ananth CV. Practice Patterns Among Board-Certified Reproductive Endocrinologists Regarding High-Order Multiple Gestations Obstetrics And Gynecology 2002, 99: 763-770. PMID: 11978285, DOI: 10.1097/00006250-200205000-00016.
- Seifer DB, MacLaughlin DT, Christian BP, Feng B, Shelden RM. Early follicular serum müllerian-inhibiting substance levels are associated with ovarian response during assisted reproductive technology cycles Fertility And Sterility 2002, 77: 468-471. PMID: 11872196, DOI: 10.1016/s0015-0282(01)03201-0.
- Seifer DB, Feng B, Shelden RM, Chen S, Dreyfus CF. Brain-derived neurotrophic factor: a novel human ovarian follicular protein. The Journal Of Clinical Endocrinology & Metabolism 2002, 87: 655-9. PMID: 11836300, DOI: 10.1210/jcem.87.2.8213.
- Hock DL, Sharafi K, Dagostino L, Kemmann E, Seifer DB. Contribution of diminished ovarian reserve to hypofertility associated with endometriosis. The Journal Of Reproductive Medicine 2001, 46: 7-10. PMID: 11209637.
- Hock DL, Seifer DB. NEW TREATMENTS OF HYPERANDROGENISM AND HIRSUTISM Obstetrics And Gynecology Clinics Of North America 2000, 27: 567-581. PMID: 10958004, DOI: 10.1016/s0889-8545(05)70156-x.
- Graczykowski JW, Seifer DB. Diagnosis of acute and persistent ectopic pregnancy. Clinical Obstetrics & Gynecology 1999, 42: 9-22; quiz 55-6. PMID: 10073295, DOI: 10.1097/00003081-199903000-00005.
- Houmard BS, Seifer DB. Infertility treatment and informed consent: current practices of reproductive endocrinologists. Obstetrics And Gynecology 1999, 93: 252-7. PMID: 9932565, DOI: 10.1016/s0029-7844(98)00389-5.
- Bopp BL, Seifer DB. Oocyte loss and the perimenopause. Clinical Obstetrics & Gynecology 1998, 41: 898-911. PMID: 9917945, DOI: 10.1097/00003081-199812000-00016.
- Seifer DB, Naftolin F. Moving toward an earlier and better understanding of perimenopause. Fertility And Sterility 1998, 69: 387-8. PMID: 9531863, DOI: 10.1016/s0015-0282(97)00564-5.
- Lambert-Messerlian GM, Steinhoff M, Zheng W, Canick JA, Gajewski WH, Seifer DB, Schneyer AL. Multiple Immunoreactive Inhibin Proteins in Serum from Postmenopausal Women with Epithelial Ovarian Cancer Gynecologic Oncology 1997, 65: 512-516. PMID: 9190984, DOI: 10.1006/gyno.1997.4719.
- Haning RV, Seifer DB, Wheeler CA, Frishman GN, Silver H, Pierce DJ. Effects of fetal number and multifetal reduction on length of in vitro fertilization pregnancies. Obstetrics And Gynecology 1996, 87: 964-8. PMID: 8649707, DOI: 10.1016/0029-7844(96)00059-2.
- Seifer DB, Gardiner AC, Lambert-Messerlian G, Schneyer AL. Differential secretion of dimeric inhibin in cultured luteinized granulosa cells as a function of ovarian reserve. The Journal Of Clinical Endocrinology & Metabolism 1996, 81: 736-9. PMID: 8636296, DOI: 10.1210/jcem.81.2.8636296.
- Tallo CP, Vohr B, Oh W, Rubin LP, Seifer DB, Haning RV. Maternal and neonatal morbidity associated with in vitro fertilization The Journal Of Pediatrics 1995, 127: 794-800. PMID: 7472838, DOI: 10.1016/s0022-3476(95)70175-3.
- Seifer DB, Giudice LC, Dsupin BA, Haning RV, Frishman GN, Burger HG. Follicular fluid insulin-like growth factor-I and insulin-like growth factor-II concentrations vary as a function of day 3 serum follicle stimulating hormone. Human Reproduction 1995, 10: 804-6. PMID: 7650124, DOI: 10.1093/oxfordjournals.humrep.a136042.
- Mark HF, Meyers-Seifer CH, Seifer DB, Demoranville BM, Jackson IM. Assessment of sex chromosome composition using fluorescent in situ hybridization as an adjunct to GTG-banding. Annals Of Clinical & Laboratory Science 1995, 25: 402-8. PMID: 7486815.
- Lyons CA, Wheeler CA, Frishman GN, Hackett RJ, Seifer DB, Haning RV. Early and late presentation of the ovarian hyperstimulation syndrome: two distinct entities with different risk factors. Human Reproduction 1994, 9: 792-9. PMID: 7929724, DOI: 10.1093/oxfordjournals.humrep.a138598.
- Cole LA, Kardana A, Seifer DB, Bohler HC. Urine hCG beta-subunit core fragment, a sensitive test for ectopic pregnancy. The Journal Of Clinical Endocrinology & Metabolism 1994, 78: 497-9. PMID: 7508952, DOI: 10.1210/jcem.78.2.7508952.
- Haning RV, Hua JJ, Hackett RJ, Wheeler CA, Frishman GN, Seifer DB, Dahl CA, Burger HG. Dehydroepiandrosterone sulfate and anovulation increase serum inhibin and affect follicular function during administration of gonadotropins. The Journal Of Clinical Endocrinology & Metabolism 1994, 78: 145-9. PMID: 8288697, DOI: 10.1210/jcem.78.1.8288697.
- Seifer DB, Gutmann JN, Grant WD, Kamps CA, DeCherney AH. Comparison of persistent ectopic pregnancy after laparoscopic salpingostomy versus salpingostomy at laparotomy for ectopic pregnancy. Obstetrics And Gynecology 1993, 81: 378-82. PMID: 8437790.
- Seifer DB, MacLaughlin DT, Penzias AS, Behrman HR, Asmundson L, Donahoe PK, Haning RV, Flynn SD. Gonadotropin-releasing hormone agonist-induced differences in granulosa cell cycle kinetics are associated with alterations in follicular fluid müllerian-inhibiting substance and androgen content. The Journal Of Clinical Endocrinology & Metabolism 1993, 76: 711-4. PMID: 8445031, DOI: 10.1210/jcem.76.3.8445031.
- Seifer DB, Honig J, Penzias AS, Lavy G, Nadkarni PM, Jones EE, DeCherney AH, Flynn SD. Flow cytometric analysis of deoxyribonucleic acid in human granulosa cells as a function of chronological age and ovulation induction regimen. The Journal Of Clinical Endocrinology & Metabolism 1992, 75: 636-40. PMID: 1639962, DOI: 10.1210/jcem.75.2.1639962.
- Schwartz LB, Seifer DB. Diagnostic imaging of adnexal masses. A review. The Journal Of Reproductive Medicine 1992, 37: 63-71. PMID: 1548639.
- Seifer DB, Meyers-Seifer CH, Lavy G, Genel M, DeCherney AH, Yang-Feng TL. Laparoscopic adnexectomy in a prepubertal Turner mosaic female with isodicentric Y. Human Reproduction 1991, 6: 566-7. PMID: 1918308, DOI: 10.1093/oxfordjournals.humrep.a137380.
- Hershlag A, Seifer DB, Carcangiu ML, Patton DL, Diamond MP, DeCherney AH. Salpingoscopy: light microscopic and electron microscopic correlations. Obstetrics And Gynecology 1991, 77: 399-405. PMID: 1992407.
- Seifer DB, Gutmann JN, Doyle MB, Jones EE, Diamond MP, DeCherney AH. Persistent ectopic pregnancy following laparoscopic linear salpingostomy. Obstetrics And Gynecology 1990, 76: 1121-5. PMID: 1700350.
- Miller DS, Seifer DB. Endocrinologic aspects of gestational trophoblastic diseases. International Journal Of Fertility 1990, 35: 137-53. PMID: 1973918.
- Seifer DB, Diamond MP, DeCherney AH. An Appraisal of Barrier Agents in the Reduction of Adhesion Formation Following Surgery Journal Of Gynecologic Surgery 1990, 6: 3-10. PMID: 10149754, DOI: 10.1089/gyn.1990.6.3.
- Seifer DB, Henry JB. The impact of technology on the clinical decision making of house staff. New York State Journal Of Medicine 1989, 89: 444-5. PMID: 2779878.
- Seifer DB, Kennedy AW, Webster KD, Vanderbrug Medendorp S, Isakson DG. Outcome of primary cytoreduction surgery for advanced epithelial ovarian carcinoma. Cleveland Clinic Journal Of Medicine 1988, 55: 555-60. PMID: 3228977, DOI: 10.3949/ccjm.55.6.555.
- Adelson MD, Baggish MS, Seifer DB, Cassell SL, Thompson MA. Cytoreduction of ovarian cancer with the Cavitron ultrasonic surgical aspirator. Obstetrics And Gynecology 1988, 72: 140-3. PMID: 3380505.
- Seifer DB, Albright GA. Epidural anesthesia in toxemia of pregnancy. The New England Journal Of Medicine 1986, 314: 582-3. PMID: 3945301, DOI: 10.1056/NEJM198602273140916.
- Catanzarite VA, Bhat N, Seifer DB, Cortina P, Fainstat T. Successful intrauterine pregnancy after unilateral hysterectomy in a patient with uterus didelphys. A case report. The Journal Of Reproductive Medicine 1986, 31: 133-5. PMID: 3959018.
- Lombard CM, Moore MH, Seifer DB. Diagnosis of systemic polyarteritis nodosa following total abdominal hysterectomy and bilateral salpingo-oophorectomy: a case report. International Journal Of Gynecological Pathology : Official Journal Of The International Society Of Gynecological Pathologists 1986, 5: 63-8. PMID: 2870032, DOI: 10.1097/00004347-198603000-00007.
- Seifer DB, Ferguson JE, Behrens CM, Zemel S, Stevenson DK, Ross JC. Nonimmune hydrops fetalis in association with hemangioma of the umbilical cord. Obstetrics And Gynecology 1985, 66: 283-6. PMID: 3895076.
- Seifer DB, Sandberg EC, Ueland K, Sladen RN. Water intoxication and hyponatremic encephalopathy from the use of an oxytocin nasal spray. A case report. The Journal Of Reproductive Medicine 1985, 30: 225-8. PMID: 3923190.
- Kresch AJ, Seifer DB, Sachs LB, Barrese I. Laparoscopy in 100 women with chronic pelvic pain. Obstetrics And Gynecology 1984, 64: 672-4. PMID: 6238250.
- Lewinstein C, Silberman H, Goren G, Feinstein E, Berne TV, Seifer D, Witt R, Gonsier A, Greaney G. Experience with a coaxial dialysis cannula for temporary vascular access. Transactions - American Society For Artificial Internal Organs 1983, 29: 357-9. PMID: 6673252.
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