- Yale Fertility Center200 West Campus DriveFl 2ndOrange, CT 06477
David Frankfurter, MD
he/him/his
Reproductive Endocrinology & Infertility, Obstetrics, Gynecology & Reproductive Sciences
Patient type treated
Adult
Accepting new patients
Yes
Referral required
From patients or physicians
Titles
- Professor of Obstetrics, Gynecology and Reproductive Sciences
Education & Training
- FellowshipHarvard University School of Medicine (1998)
- FellowshipTufts University School of Medicine (1996)
- ResidencyYale School of Medicine (1995)
- MDYale Medical School (1991)
- BSSyracuse University , Psychology (1986)
Additional Information
Publications
- Seifer D, Wang S, Frankfurter D. Cumulative live birth rates with autologous oocytes plateau with fewer number of cycles for each year of age > 42. Reproductive Biology And Endocrinology 2023, 21: 94. PMID: 37872609, PMCID: PMC10591412, DOI: 10.1186/s12958-023-01144-z.
- Frankfurter D, Kliman H. Progress on the Endometrium. Obstetrics And Gynecology Clinics Of North America 2023, 50: 677-694. PMID: 37914487, DOI: 10.1016/j.ogc.2023.09.002.
- Humm K, Frankfurter D. The road to validating preimplantation genetic testing for aneuploidy; are we there yet? Fertility And Sterility 2021, 115: 585-586. PMID: 33558020, DOI: 10.1016/j.fertnstert.2020.12.029.
- Frishman G, Raker C, Frankfurter D. Well-being in trainee and faculty physicians. Medical Education Online 2021, 26: 1950107. PMID: 34252014, PMCID: PMC8276666, DOI: 10.1080/10872981.2021.1950107.
- McLeland-Wieser H, Young H, Neumann L, Crites J, Moody D, Irwig M, Frankfurter D, Perry M. Association of Urinary THC Concentrations and Sperm Abnormalities in US Urban Men. ISEE Conference Abstracts 2020, 2020 DOI: 10.1289/isee.2020.virtual.p-1117.
- McCray N, Young H, Irwig M, Frankfurter D, Schwartz A, Witmyer J, Hynes M, Jayanthi V, Marcus M, Patel M, Perry M. The Association Between Race, Obesity, and Sperm Quality Among Men Attending a University Physician Practice in Washington, DC. American Journal Of Men's Health 2020, 14: 1557988320925985. PMID: 32602769, PMCID: PMC7328221, DOI: 10.1177/1557988320925985.
- Kliman HJ, Frankfurter D. Clinical approach to recurrent implantation failure: evidence-based evaluation of the endometrium. Fertility And Sterility 2019, 111: 618-628. PMID: 30929719, DOI: 10.1016/j.fertnstert.2019.02.011.
- Grant K, Comstock I, Humm K, Lalwani S, Peak D, Witmyer J, Frankfurter D. Trophectodermal euploidy rates as a function of time to blastocoele expansion. Fertility And Sterility 2018, 110: e351. DOI: 10.1016/j.fertnstert.2018.07.981.
- Godiwala P, Humm K, Comstock I, Witmyer J, Peak D, Sparks A, Lalwani S, Frankfurter D. Performance of retrieved oocytes that mature from metaphase I (MI) to metaphase II (MII) after a GnRH agonist trigger. Fertility And Sterility 2018, 110: e312. DOI: 10.1016/j.fertnstert.2018.07.881.
- Comstock I, Frankfurter D. Are too many eggs truly too many? Fertility And Sterility 2018, 110: 632-633. PMID: 30196952, DOI: 10.1016/j.fertnstert.2018.05.030.
- Plowden T, Millan N, Owen C, Healy M, Banks N, Hsieh M, Fitzhugh C, Witmyer J, Peak D, Frankfurter D, DeCherney A, Tisdale J, Wolff E. Fertility Preservation for Women with Sickle Cell Disease (SCD). Blood 2015, 126: 3408. DOI: 10.1182/blood.v126.23.3408.3408.
- Lalwani S, Witmyer J, Gaba N, Frankfurter D. Preimplantation Genetic Screening. Topics In Obstetrics & Gynecology 2015, 35: 1-5. DOI: 10.1097/01.pgo.0000471712.79930.33.
- Orkunoglu-Suer F, Harralson A, Frankfurter D, Gindoff P, O’Brien T. Targeted single molecule sequencing methodology for ovarian hyperstimulation syndrome. BMC Genomics 2015, 16: 264. PMID: 25888426, PMCID: PMC4397691, DOI: 10.1186/s12864-015-1451-2.
- Frankfurter D. Getting Pregnant with PCOS. 2015, 317-326. DOI: 10.1007/978-1-4939-2059-4_38.
- O’Brien T, Harralson A, Frankfurter D, Gindoff P, Orkunoglu-Suer F. Development of a targeted single molecule sequencing panel for ovarian hyperstimulation syndrome. Fertility And Sterility 2014, 102: e122. DOI: 10.1016/j.fertnstert.2014.07.417.
- O’Brien T, Harralson A, Tran T, Gindoff I, Orkunoglu-Suer F, Frankfurter D, Gindoff P. Kinase insert domain receptor/vascular endothelial growth factor receptor 2 (KDR) genetic variation is associated with ovarian hyperstimulation syndrome. Reproductive Biology And Endocrinology 2014, 12: 36. PMID: 24886133, PMCID: PMC4024119, DOI: 10.1186/1477-7827-12-36.
- O’Brien T, Kalmin M, Harralson A, Clark A, Gindoff I, Simmens S, Frankfurter D, Gindoff P. Association between the luteinizing hormone/chorionic gonadotropin receptor (LHCGR) rs4073366 polymorphism and ovarian hyperstimulation syndrome during controlled ovarian hyperstimulation. Reproductive Biology And Endocrinology 2013, 11: 71. PMID: 23883350, PMCID: PMC3727944, DOI: 10.1186/1477-7827-11-71.
- Frankfurter D. Human assisted reproductive technology: future trends in laboratory and clinical practice David K. Gardner, Bartros R.M.B. Rizk, Tommaso Falcone, eds. Human Assisted Reproductive Technology: Future Trends in Laboratory and Clinical Practice. Cambridge, United Kingdom: Cambridge University Press; 336 pages; $110.00. Fertility And Sterility 2012, 98: 1060. DOI: 10.1016/j.fertnstert.2012.08.019.
- Gindoff P, Frankfurter D, Dayal M, Marshall M, Harralson A, O'Brien T. Distribution of LH receptor (LHCGR) polymorphisms in patients undergoing controlled ovarian stimulation (COS) – IVF. Fertility And Sterility 2012, 98: s16. DOI: 10.1016/j.fertnstert.2012.07.060.
- Skora D, Frankfurter D. Adverse Perinatal Events Associated with ART. Seminars In Reproductive Medicine 2012, 30: 084-091. PMID: 22549708, DOI: 10.1055/s-0032-1307416.
- Ambroggio J, Gindoff P, Dayal M, Khaldi R, Peak D, Frankfurter D, Dubey A. Multinucleation of a sibling blastomere on day 2 suggests unsuitability for embryo transfer in IVF–preimplantation genetic screening cycles. Fertility And Sterility 2011, 96: 856-859. PMID: 21851938, DOI: 10.1016/j.fertnstert.2011.07.1110.
- Frankfurter D. A new paradigm for studying and treating primary ovarian insufficiency: the community of practice. Fertility And Sterility 2011, 95: 1899-1900. PMID: 21444072, DOI: 10.1016/j.fertnstert.2011.03.007.
- Dayal M, Frankfurter D, Athanasiadis I, Peak D, Dubey A, Gindoff P. Day 2 embryo transfer (ET) and day 3 ET afford similar reproductive outcomes in the poor responder. Fertility And Sterility 2010, 95: 1130-1132. PMID: 21071020, DOI: 10.1016/j.fertnstert.2010.10.010.
- Dubey A, Dayal M, Peak D, Khaldi R, Frankfurter D, Gindoff P. Prefered day of embryo transfer (day 4 vs day 5) of normal PGD embryos depends on develpomental stage. Fertility And Sterility 2010, 94: s127. DOI: 10.1016/j.fertnstert.2010.07.514.
- Dubey A, Khaldi R, Dayal M, Frankfurter D, Ambroggio J, Gindoff P. Blastomere multinucleation on day 2 post egg retrieval predicts an increased risk for aneuploidy with PGD. Fertility And Sterility 2010, 94: s127. DOI: 10.1016/j.fertnstert.2010.07.512.
- Dayal M, Gindoff P, Zarek S, Peak D, Dubey A, Frankfurter D. Profound teratospermia does not influence sex chromosomal aneuploidy rate in in vitro fertilization–preimplantation genetic diagnosis cycles. Fertility And Sterility 2009, 93: 666-668. PMID: 19732890, DOI: 10.1016/j.fertnstert.2009.07.1006.
- Dayal M, Frankfurter D, Moawad G, Peak D, Dubey A, Gindoff P. A new threshold sperm index predicts IUI outcome. Fertility And Sterility 2009, 92: s144. DOI: 10.1016/j.fertnstert.2009.07.1237.
- Robinson J, Dayal M, Gindoff P, Frankfurter D. A novel surgical treatment for cesarean scar pregnancy: laparoscopically assisted operative hysteroscopy. Fertility And Sterility 2009, 92: 1497.e13-1497.e16. PMID: 19683711, DOI: 10.1016/j.fertnstert.2009.07.996.
- Dayal M, Frankfurter D, O'Hern C, Peak D, Dubey A, Gindoff P. The use of lead follicle diameter to initiate gonadotropin-releasing hormone antagonist does not affect in vitro fertilization clinical pregnancy, implantation, or live birth rates: a prospective, randomized study. Fertility And Sterility 2009, 92: 2047-2049. PMID: 19591990, DOI: 10.1016/j.fertnstert.2009.05.083.
- Frankfurter D, Dayal M, Peak D, Dubey A, Gindoff P. Profound teratospermia does not influence sex chromosomal aneuploidy rates in IVF-PGD cycles. Fertility And Sterility 2008, 90: s89. DOI: 10.1016/j.fertnstert.2008.07.956.
- Dayal M, Frankfurter D, Moawad G, Peak D, Dubey A, Gindoff P. A novel semen measure for predicting post-IUI pregnancy: the absolute motile morphology count. Fertility And Sterility 2008, 90: s486. DOI: 10.1016/j.fertnstert.2008.07.071.
- Dayal M, Gindoff P, Dubey A, Spitzer T, Bergin A, Peak D, Frankfurter D. Does ethnicity influence in vitro fertilization (IVF) birth outcomes? Fertility And Sterility 2008, 91: 2414-2418. PMID: 18691706, DOI: 10.1016/j.fertnstert.2008.03.055.
- Dayal M, Gindoff P, Sarhan A, Dubey A, Peak D, Frankfurter D. Effects of triploidy after intracytoplasmic sperm injection on in vitro fertilization cycle outcome. Fertility And Sterility 2008, 91: 101-105. PMID: 18249397, DOI: 10.1016/j.fertnstert.2007.11.033.
- Dean M, Frankfurter D, Dayal M, Dubey A, Peak D, Gindoff P. Pregnant and non-pregnant IVF-ET cycles yield adequate endometrial development regardless of serum estradiol levels. Fertility And Sterility 2007, 88: s294. DOI: 10.1016/j.fertnstert.2007.07.991.
- Dubey A, Dayal M, Frankfurter D, Balazy P, Peak D, Gindoff P. The influence of sperm morphology on preimplantation genetic diagnosis cycles outcome. Fertility And Sterility 2007, 89: 1665-1669. PMID: 17727848, DOI: 10.1016/j.fertnstert.2007.06.052.
- Frankfurter D, Dayal M, Dubey A, Peak D, Gindoff P. Novel follicular-phase gonadotropin-releasing hormone antagonist stimulation protocol for in vitro fertilization in the poor responder. Fertility And Sterility 2007, 88: 1442-1445. PMID: 17481626, DOI: 10.1016/j.fertnstert.2007.01.022.
- Dayal M, Dubey A, Frankfurter D, Peak D, Gindoff P. Second cycle: to hatch or not to hatch? Fertility And Sterility 2007, 88: 718-720. PMID: 17320876, DOI: 10.1016/j.fertnstert.2006.11.147.
- Dubey A, Dayal M, Frankfurter D, Balazy P, Peak D, Gindoff P. O-149 The influence of sperm morphology on IVF-PGD cycle outcome. Fertility And Sterility 2006, 86: s63-s64. DOI: 10.1016/j.fertnstert.2006.07.172.
- Dayal M, Frankfurter D, Peak D, Dubey A, Gindoff P. P-815 Late initiation of GnRH antagonist does not jeopardize IVF outcome: A randomized study. Fertility And Sterility 2006, 86: s436. DOI: 10.1016/j.fertnstert.2006.07.1202.
- Dayal M, Frankfurter D, Peak D, Dubey A, Gindoff P. P-501 Polyploidy following ICSI impacts IVF outcome. Fertility And Sterility 2006, 86: s320-s321. DOI: 10.1016/j.fertnstert.2006.07.865.
- Silberstein T, Trimarchi J, Shackelton R, Weitzen S, Frankfurter D, Plosker S. Ultrasound-guided miduterine cavity embryo transfer is associated with a decreased incidence of retained embryos in the transfer catheter. Fertility And Sterility 2005, 84: 1510-1512. PMID: 16275257, DOI: 10.1016/j.fertnstert.2005.06.023.
- Dayal M, Gindoff P, Dubey A, Bergin A, Peak D, Frankfurter D. The Influence of Ethnicity on IVF Outcome. Fertility And Sterility 2005, 84: s250. DOI: 10.1016/j.fertnstert.2005.07.648.
- Dayal M, Frankfurter D, Peak D, Dubey A, Gindoff P. Day 2 Embryo Transfer (ET) and Day 3 ET Afford Similar Reproductive Outcomes in the Poor Responder. Fertility And Sterility 2005, 84: s327. DOI: 10.1016/j.fertnstert.2005.07.854.
- Silberstein T, Weitzen S, Frankfurter D, Trimarchi J, Keefe D, Plosker S. Cannulation of a resistant internal os with the malleable outer sheath of a coaxial soft embryo transfer catheter does not affect in vitro fertilization–embryo transfer outcome. Fertility And Sterility 2004, 82: 1402-1406. PMID: 15533367, DOI: 10.1016/j.fertnstert.2004.04.044.
- Frankfurter D, Dayal M, Dubey A, Peak D, Gindoff P. Mid follicular GnRH antagonist suppression: A novel means of improving follicular recruitment in the poor responder. Fertility And Sterility 2004, 82: s125. DOI: 10.1016/j.fertnstert.2004.07.316.
- Dayal M, Dubey A, Frankfurter D, Peak D, Gindoff P. Impact of assisted hatching (AH) in patients displaying prior implantation failure. Fertility And Sterility 2004, 82: s258. DOI: 10.1016/j.fertnstert.2004.07.688.
- Frankfurter D, Trimarchi J, Hackett R, Meng L, Keefe D. Monozygotic pregnancies from transfers of zona-free blastocysts. Fertility And Sterility 2004, 82: 483-485. PMID: 15302309, DOI: 10.1016/j.fertnstert.2004.02.105.
- Frankfurter D, Keefe D, Trimarchi J. Reply of the authors. Fertility And Sterility 2004, 81: 1715-1716. DOI: 10.1016/j.fertnstert.2004.03.005.
- Blazar A, Hogan J, Frankfurter D, Hackett R, Keefe D. Serum estradiol positively predicts outcomes in patients undergoing in vitro fertilization. Fertility And Sterility 2004, 81: 1707-1709. PMID: 15193504, DOI: 10.1016/j.fertnstert.2003.10.039.
- Frankfurter D, Trimarchi J, Silva C, Keefe D. Middle to lower uterine segment embryo transfer improves implantation and pregnancy rates compared with fundal embryo transfer. Fertility And Sterility 2004, 81: 1273-1277. PMID: 15136089, DOI: 10.1016/j.fertnstert.2003.11.026.
- Frankfurter D, Keefe D. Reply of the authors. Fertility And Sterility 2003, 80: 1532-1533. DOI: 10.1016/s0015-0282(03)02220-9.
- Frankfurter D, Keefe D, Trimarchi J. Day 2 embryo transfer improves IVF-ET outcome in the poor responder. Fertility And Sterility 2003, 80: 61. DOI: 10.1016/s0015-0282(03)01966-6.
- Frankfurter D, Hackett R, Keefe D, Trimarchi J. Using 100% embryo implantation IVF cycles to identify preferred embryo development patterns—morphokinetics. Fertility And Sterility 2003, 80: 71. DOI: 10.1016/s0015-0282(03)01992-7.
- Silberstein T, Trimarchi J, Frankfurter D, Pagidas K, Keefe D, Plosker S. Reduced incidence of embryo retention in the transfer catheter after universal adaptation of mid-cavity transfer by a large multiple clinician IVF center. Fertility And Sterility 2003, 80: 127. DOI: 10.1016/s0015-0282(03)01209-3.
- Silva C, Trimarchi J, Keefe D, Frankfurter D. High incidence of ectopic pregnancy following frozen embryo transfer. Fertility And Sterility 2003, 80: 178. DOI: 10.1016/s0015-0282(03)01372-4.
- Frankfurter D. To insure or not to insure: that is the question. Fertility And Sterility 2003, 80: 24-26. PMID: 12849795, DOI: 10.1016/s0015-0282(03)00574-0.
- Frankfurter D, Silva C, Mota F, Trimarchi J, Keefe D. The transfer point is a novel measure of embryo placement. Fertility And Sterility 2003, 79: 1416-1421. PMID: 12798891, DOI: 10.1016/s0015-0282(03)00263-2.
- Blazar A, Hogan J, Frankfurter D, Hackett R, Keefe D. Serum estradiol positively predicts outcomes in patients doing IVF. Fertility And Sterility 2002, 78: s43. DOI: 10.1016/s0015-0282(02)03492-1.
- Frankfurter D, Trimarchi J, Silva C, Keefe D. Transfer of embryos to the mid- to lower uterine segment significantly improves implantation and pregnancy rates when compared to fundal embryo transfers. Fertility And Sterility 2002, 78: s45-s46. DOI: 10.1016/s0015-0282(02)03499-4.
- Frankfurter D, Hackett R, Meng L, Keefe D. Complete removal of the zona pellucida by pronase digestion prior to blastocyst embryo transfer does not eliminate monozygotic pregnancies following IVF. Fertility And Sterility 2001, 76: s144. DOI: 10.1016/s0015-0282(01)02422-0.
- Frankfurter D, Wang W, Oldenbourg R, Meng L, Hackett R, Keefe D. Follicular dynamics and ovarian stimulation influence meiotic spindle integrity during human IVF. Fertility And Sterility 2001, 76: s91-s92. DOI: 10.1016/s0015-0282(01)02274-9.
- Frankfurter D, Dinh Q, Hackett R, Keefe D, Pagidas K. Sequential Embryo Culture and Blastocyst Embryo Transfer (BET) Do Not Increase the Risk of Monozygotic (MZ) Pregnancy Outcomes Beyond That Seen With Cleavage Stage Embryo Transfer (CET). Fertility And Sterility 2000, 74: s60-s61. DOI: 10.1016/s0015-0282(00)00883-9.
Departments and Programs
Locations
- Yale Fertility Center200 West Campus DriveFl 2ndOrange, CT 06477
Titles
- Professor of Obstetrics, Gynecology and Reproductive Sciences
Education & Training
- FellowshipHarvard University School of Medicine (1998)
- FellowshipTufts University School of Medicine (1996)
- ResidencyYale School of Medicine (1995)
- MDYale Medical School (1991)
- BSSyracuse University , Psychology (1986)
Additional Information
Publications
- Seifer D, Wang S, Frankfurter D. Cumulative live birth rates with autologous oocytes plateau with fewer number of cycles for each year of age > 42. Reproductive Biology And Endocrinology 2023, 21: 94. PMID: 37872609, PMCID: PMC10591412, DOI: 10.1186/s12958-023-01144-z.
- Frankfurter D, Kliman H. Progress on the Endometrium. Obstetrics And Gynecology Clinics Of North America 2023, 50: 677-694. PMID: 37914487, DOI: 10.1016/j.ogc.2023.09.002.
- Humm K, Frankfurter D. The road to validating preimplantation genetic testing for aneuploidy; are we there yet? Fertility And Sterility 2021, 115: 585-586. PMID: 33558020, DOI: 10.1016/j.fertnstert.2020.12.029.
- Frishman G, Raker C, Frankfurter D. Well-being in trainee and faculty physicians. Medical Education Online 2021, 26: 1950107. PMID: 34252014, PMCID: PMC8276666, DOI: 10.1080/10872981.2021.1950107.
- McLeland-Wieser H, Young H, Neumann L, Crites J, Moody D, Irwig M, Frankfurter D, Perry M. Association of Urinary THC Concentrations and Sperm Abnormalities in US Urban Men. ISEE Conference Abstracts 2020, 2020 DOI: 10.1289/isee.2020.virtual.p-1117.
- McCray N, Young H, Irwig M, Frankfurter D, Schwartz A, Witmyer J, Hynes M, Jayanthi V, Marcus M, Patel M, Perry M. The Association Between Race, Obesity, and Sperm Quality Among Men Attending a University Physician Practice in Washington, DC. American Journal Of Men's Health 2020, 14: 1557988320925985. PMID: 32602769, PMCID: PMC7328221, DOI: 10.1177/1557988320925985.
- Kliman HJ, Frankfurter D. Clinical approach to recurrent implantation failure: evidence-based evaluation of the endometrium. Fertility And Sterility 2019, 111: 618-628. PMID: 30929719, DOI: 10.1016/j.fertnstert.2019.02.011.
- Grant K, Comstock I, Humm K, Lalwani S, Peak D, Witmyer J, Frankfurter D. Trophectodermal euploidy rates as a function of time to blastocoele expansion. Fertility And Sterility 2018, 110: e351. DOI: 10.1016/j.fertnstert.2018.07.981.
- Godiwala P, Humm K, Comstock I, Witmyer J, Peak D, Sparks A, Lalwani S, Frankfurter D. Performance of retrieved oocytes that mature from metaphase I (MI) to metaphase II (MII) after a GnRH agonist trigger. Fertility And Sterility 2018, 110: e312. DOI: 10.1016/j.fertnstert.2018.07.881.
- Comstock I, Frankfurter D. Are too many eggs truly too many? Fertility And Sterility 2018, 110: 632-633. PMID: 30196952, DOI: 10.1016/j.fertnstert.2018.05.030.
- Plowden T, Millan N, Owen C, Healy M, Banks N, Hsieh M, Fitzhugh C, Witmyer J, Peak D, Frankfurter D, DeCherney A, Tisdale J, Wolff E. Fertility Preservation for Women with Sickle Cell Disease (SCD). Blood 2015, 126: 3408. DOI: 10.1182/blood.v126.23.3408.3408.
- Lalwani S, Witmyer J, Gaba N, Frankfurter D. Preimplantation Genetic Screening. Topics In Obstetrics & Gynecology 2015, 35: 1-5. DOI: 10.1097/01.pgo.0000471712.79930.33.
- Orkunoglu-Suer F, Harralson A, Frankfurter D, Gindoff P, O’Brien T. Targeted single molecule sequencing methodology for ovarian hyperstimulation syndrome. BMC Genomics 2015, 16: 264. PMID: 25888426, PMCID: PMC4397691, DOI: 10.1186/s12864-015-1451-2.
- Frankfurter D. Getting Pregnant with PCOS. 2015, 317-326. DOI: 10.1007/978-1-4939-2059-4_38.
- O’Brien T, Harralson A, Frankfurter D, Gindoff P, Orkunoglu-Suer F. Development of a targeted single molecule sequencing panel for ovarian hyperstimulation syndrome. Fertility And Sterility 2014, 102: e122. DOI: 10.1016/j.fertnstert.2014.07.417.
- O’Brien T, Harralson A, Tran T, Gindoff I, Orkunoglu-Suer F, Frankfurter D, Gindoff P. Kinase insert domain receptor/vascular endothelial growth factor receptor 2 (KDR) genetic variation is associated with ovarian hyperstimulation syndrome. Reproductive Biology And Endocrinology 2014, 12: 36. PMID: 24886133, PMCID: PMC4024119, DOI: 10.1186/1477-7827-12-36.
- O’Brien T, Kalmin M, Harralson A, Clark A, Gindoff I, Simmens S, Frankfurter D, Gindoff P. Association between the luteinizing hormone/chorionic gonadotropin receptor (LHCGR) rs4073366 polymorphism and ovarian hyperstimulation syndrome during controlled ovarian hyperstimulation. Reproductive Biology And Endocrinology 2013, 11: 71. PMID: 23883350, PMCID: PMC3727944, DOI: 10.1186/1477-7827-11-71.
- Frankfurter D. Human assisted reproductive technology: future trends in laboratory and clinical practice David K. Gardner, Bartros R.M.B. Rizk, Tommaso Falcone, eds. Human Assisted Reproductive Technology: Future Trends in Laboratory and Clinical Practice. Cambridge, United Kingdom: Cambridge University Press; 336 pages; $110.00. Fertility And Sterility 2012, 98: 1060. DOI: 10.1016/j.fertnstert.2012.08.019.
- Gindoff P, Frankfurter D, Dayal M, Marshall M, Harralson A, O'Brien T. Distribution of LH receptor (LHCGR) polymorphisms in patients undergoing controlled ovarian stimulation (COS) – IVF. Fertility And Sterility 2012, 98: s16. DOI: 10.1016/j.fertnstert.2012.07.060.
- Skora D, Frankfurter D. Adverse Perinatal Events Associated with ART. Seminars In Reproductive Medicine 2012, 30: 084-091. PMID: 22549708, DOI: 10.1055/s-0032-1307416.
- Ambroggio J, Gindoff P, Dayal M, Khaldi R, Peak D, Frankfurter D, Dubey A. Multinucleation of a sibling blastomere on day 2 suggests unsuitability for embryo transfer in IVF–preimplantation genetic screening cycles. Fertility And Sterility 2011, 96: 856-859. PMID: 21851938, DOI: 10.1016/j.fertnstert.2011.07.1110.
- Frankfurter D. A new paradigm for studying and treating primary ovarian insufficiency: the community of practice. Fertility And Sterility 2011, 95: 1899-1900. PMID: 21444072, DOI: 10.1016/j.fertnstert.2011.03.007.
- Dayal M, Frankfurter D, Athanasiadis I, Peak D, Dubey A, Gindoff P. Day 2 embryo transfer (ET) and day 3 ET afford similar reproductive outcomes in the poor responder. Fertility And Sterility 2010, 95: 1130-1132. PMID: 21071020, DOI: 10.1016/j.fertnstert.2010.10.010.
- Dubey A, Dayal M, Peak D, Khaldi R, Frankfurter D, Gindoff P. Prefered day of embryo transfer (day 4 vs day 5) of normal PGD embryos depends on develpomental stage. Fertility And Sterility 2010, 94: s127. DOI: 10.1016/j.fertnstert.2010.07.514.
- Dubey A, Khaldi R, Dayal M, Frankfurter D, Ambroggio J, Gindoff P. Blastomere multinucleation on day 2 post egg retrieval predicts an increased risk for aneuploidy with PGD. Fertility And Sterility 2010, 94: s127. DOI: 10.1016/j.fertnstert.2010.07.512.
- Dayal M, Gindoff P, Zarek S, Peak D, Dubey A, Frankfurter D. Profound teratospermia does not influence sex chromosomal aneuploidy rate in in vitro fertilization–preimplantation genetic diagnosis cycles. Fertility And Sterility 2009, 93: 666-668. PMID: 19732890, DOI: 10.1016/j.fertnstert.2009.07.1006.
- Dayal M, Frankfurter D, Moawad G, Peak D, Dubey A, Gindoff P. A new threshold sperm index predicts IUI outcome. Fertility And Sterility 2009, 92: s144. DOI: 10.1016/j.fertnstert.2009.07.1237.
- Robinson J, Dayal M, Gindoff P, Frankfurter D. A novel surgical treatment for cesarean scar pregnancy: laparoscopically assisted operative hysteroscopy. Fertility And Sterility 2009, 92: 1497.e13-1497.e16. PMID: 19683711, DOI: 10.1016/j.fertnstert.2009.07.996.
- Dayal M, Frankfurter D, O'Hern C, Peak D, Dubey A, Gindoff P. The use of lead follicle diameter to initiate gonadotropin-releasing hormone antagonist does not affect in vitro fertilization clinical pregnancy, implantation, or live birth rates: a prospective, randomized study. Fertility And Sterility 2009, 92: 2047-2049. PMID: 19591990, DOI: 10.1016/j.fertnstert.2009.05.083.
- Frankfurter D, Dayal M, Peak D, Dubey A, Gindoff P. Profound teratospermia does not influence sex chromosomal aneuploidy rates in IVF-PGD cycles. Fertility And Sterility 2008, 90: s89. DOI: 10.1016/j.fertnstert.2008.07.956.
- Dayal M, Frankfurter D, Moawad G, Peak D, Dubey A, Gindoff P. A novel semen measure for predicting post-IUI pregnancy: the absolute motile morphology count. Fertility And Sterility 2008, 90: s486. DOI: 10.1016/j.fertnstert.2008.07.071.
- Dayal M, Gindoff P, Dubey A, Spitzer T, Bergin A, Peak D, Frankfurter D. Does ethnicity influence in vitro fertilization (IVF) birth outcomes? Fertility And Sterility 2008, 91: 2414-2418. PMID: 18691706, DOI: 10.1016/j.fertnstert.2008.03.055.
- Dayal M, Gindoff P, Sarhan A, Dubey A, Peak D, Frankfurter D. Effects of triploidy after intracytoplasmic sperm injection on in vitro fertilization cycle outcome. Fertility And Sterility 2008, 91: 101-105. PMID: 18249397, DOI: 10.1016/j.fertnstert.2007.11.033.
- Dean M, Frankfurter D, Dayal M, Dubey A, Peak D, Gindoff P. Pregnant and non-pregnant IVF-ET cycles yield adequate endometrial development regardless of serum estradiol levels. Fertility And Sterility 2007, 88: s294. DOI: 10.1016/j.fertnstert.2007.07.991.
- Dubey A, Dayal M, Frankfurter D, Balazy P, Peak D, Gindoff P. The influence of sperm morphology on preimplantation genetic diagnosis cycles outcome. Fertility And Sterility 2007, 89: 1665-1669. PMID: 17727848, DOI: 10.1016/j.fertnstert.2007.06.052.
- Frankfurter D, Dayal M, Dubey A, Peak D, Gindoff P. Novel follicular-phase gonadotropin-releasing hormone antagonist stimulation protocol for in vitro fertilization in the poor responder. Fertility And Sterility 2007, 88: 1442-1445. PMID: 17481626, DOI: 10.1016/j.fertnstert.2007.01.022.
- Dayal M, Dubey A, Frankfurter D, Peak D, Gindoff P. Second cycle: to hatch or not to hatch? Fertility And Sterility 2007, 88: 718-720. PMID: 17320876, DOI: 10.1016/j.fertnstert.2006.11.147.
- Dubey A, Dayal M, Frankfurter D, Balazy P, Peak D, Gindoff P. O-149 The influence of sperm morphology on IVF-PGD cycle outcome. Fertility And Sterility 2006, 86: s63-s64. DOI: 10.1016/j.fertnstert.2006.07.172.
- Dayal M, Frankfurter D, Peak D, Dubey A, Gindoff P. P-815 Late initiation of GnRH antagonist does not jeopardize IVF outcome: A randomized study. Fertility And Sterility 2006, 86: s436. DOI: 10.1016/j.fertnstert.2006.07.1202.
- Dayal M, Frankfurter D, Peak D, Dubey A, Gindoff P. P-501 Polyploidy following ICSI impacts IVF outcome. Fertility And Sterility 2006, 86: s320-s321. DOI: 10.1016/j.fertnstert.2006.07.865.
- Silberstein T, Trimarchi J, Shackelton R, Weitzen S, Frankfurter D, Plosker S. Ultrasound-guided miduterine cavity embryo transfer is associated with a decreased incidence of retained embryos in the transfer catheter. Fertility And Sterility 2005, 84: 1510-1512. PMID: 16275257, DOI: 10.1016/j.fertnstert.2005.06.023.
- Dayal M, Gindoff P, Dubey A, Bergin A, Peak D, Frankfurter D. The Influence of Ethnicity on IVF Outcome. Fertility And Sterility 2005, 84: s250. DOI: 10.1016/j.fertnstert.2005.07.648.
- Dayal M, Frankfurter D, Peak D, Dubey A, Gindoff P. Day 2 Embryo Transfer (ET) and Day 3 ET Afford Similar Reproductive Outcomes in the Poor Responder. Fertility And Sterility 2005, 84: s327. DOI: 10.1016/j.fertnstert.2005.07.854.
- Silberstein T, Weitzen S, Frankfurter D, Trimarchi J, Keefe D, Plosker S. Cannulation of a resistant internal os with the malleable outer sheath of a coaxial soft embryo transfer catheter does not affect in vitro fertilization–embryo transfer outcome. Fertility And Sterility 2004, 82: 1402-1406. PMID: 15533367, DOI: 10.1016/j.fertnstert.2004.04.044.
- Frankfurter D, Dayal M, Dubey A, Peak D, Gindoff P. Mid follicular GnRH antagonist suppression: A novel means of improving follicular recruitment in the poor responder. Fertility And Sterility 2004, 82: s125. DOI: 10.1016/j.fertnstert.2004.07.316.
- Dayal M, Dubey A, Frankfurter D, Peak D, Gindoff P. Impact of assisted hatching (AH) in patients displaying prior implantation failure. Fertility And Sterility 2004, 82: s258. DOI: 10.1016/j.fertnstert.2004.07.688.
- Frankfurter D, Trimarchi J, Hackett R, Meng L, Keefe D. Monozygotic pregnancies from transfers of zona-free blastocysts. Fertility And Sterility 2004, 82: 483-485. PMID: 15302309, DOI: 10.1016/j.fertnstert.2004.02.105.
- Frankfurter D, Keefe D, Trimarchi J. Reply of the authors. Fertility And Sterility 2004, 81: 1715-1716. DOI: 10.1016/j.fertnstert.2004.03.005.
- Blazar A, Hogan J, Frankfurter D, Hackett R, Keefe D. Serum estradiol positively predicts outcomes in patients undergoing in vitro fertilization. Fertility And Sterility 2004, 81: 1707-1709. PMID: 15193504, DOI: 10.1016/j.fertnstert.2003.10.039.
- Frankfurter D, Trimarchi J, Silva C, Keefe D. Middle to lower uterine segment embryo transfer improves implantation and pregnancy rates compared with fundal embryo transfer. Fertility And Sterility 2004, 81: 1273-1277. PMID: 15136089, DOI: 10.1016/j.fertnstert.2003.11.026.
- Frankfurter D, Keefe D. Reply of the authors. Fertility And Sterility 2003, 80: 1532-1533. DOI: 10.1016/s0015-0282(03)02220-9.
- Frankfurter D, Keefe D, Trimarchi J. Day 2 embryo transfer improves IVF-ET outcome in the poor responder. Fertility And Sterility 2003, 80: 61. DOI: 10.1016/s0015-0282(03)01966-6.
- Frankfurter D, Hackett R, Keefe D, Trimarchi J. Using 100% embryo implantation IVF cycles to identify preferred embryo development patterns—morphokinetics. Fertility And Sterility 2003, 80: 71. DOI: 10.1016/s0015-0282(03)01992-7.
- Silberstein T, Trimarchi J, Frankfurter D, Pagidas K, Keefe D, Plosker S. Reduced incidence of embryo retention in the transfer catheter after universal adaptation of mid-cavity transfer by a large multiple clinician IVF center. Fertility And Sterility 2003, 80: 127. DOI: 10.1016/s0015-0282(03)01209-3.
- Silva C, Trimarchi J, Keefe D, Frankfurter D. High incidence of ectopic pregnancy following frozen embryo transfer. Fertility And Sterility 2003, 80: 178. DOI: 10.1016/s0015-0282(03)01372-4.
- Frankfurter D. To insure or not to insure: that is the question. Fertility And Sterility 2003, 80: 24-26. PMID: 12849795, DOI: 10.1016/s0015-0282(03)00574-0.
- Frankfurter D, Silva C, Mota F, Trimarchi J, Keefe D. The transfer point is a novel measure of embryo placement. Fertility And Sterility 2003, 79: 1416-1421. PMID: 12798891, DOI: 10.1016/s0015-0282(03)00263-2.
- Blazar A, Hogan J, Frankfurter D, Hackett R, Keefe D. Serum estradiol positively predicts outcomes in patients doing IVF. Fertility And Sterility 2002, 78: s43. DOI: 10.1016/s0015-0282(02)03492-1.
- Frankfurter D, Trimarchi J, Silva C, Keefe D. Transfer of embryos to the mid- to lower uterine segment significantly improves implantation and pregnancy rates when compared to fundal embryo transfers. Fertility And Sterility 2002, 78: s45-s46. DOI: 10.1016/s0015-0282(02)03499-4.
- Frankfurter D, Hackett R, Meng L, Keefe D. Complete removal of the zona pellucida by pronase digestion prior to blastocyst embryo transfer does not eliminate monozygotic pregnancies following IVF. Fertility And Sterility 2001, 76: s144. DOI: 10.1016/s0015-0282(01)02422-0.
- Frankfurter D, Wang W, Oldenbourg R, Meng L, Hackett R, Keefe D. Follicular dynamics and ovarian stimulation influence meiotic spindle integrity during human IVF. Fertility And Sterility 2001, 76: s91-s92. DOI: 10.1016/s0015-0282(01)02274-9.
- Frankfurter D, Dinh Q, Hackett R, Keefe D, Pagidas K. Sequential Embryo Culture and Blastocyst Embryo Transfer (BET) Do Not Increase the Risk of Monozygotic (MZ) Pregnancy Outcomes Beyond That Seen With Cleavage Stage Embryo Transfer (CET). Fertility And Sterility 2000, 74: s60-s61. DOI: 10.1016/s0015-0282(00)00883-9.
Departments and Programs
Locations
- Yale Fertility Center200 West Campus DriveFl 2ndOrange, CT 06477
- Yale Fertility Center200 West Campus DriveFl 2ndOrange, CT 06477