Brian Smith, MD
Laboratory Medicine, Hematopathology, Hematology & Oncology, Internal Medicine
Titles
- Professor of Laboratory Medicine, of Biomedical Engineering, of Medicine (Hematology) and of Pediatrics
- Deputy Dean for Research, (Clinical and Translational)
- Co-Director, Yale Center for Clinical Investigation (YCCI)
- Director, Clinical Immunology Laboratory, Laboratory Medicine
- Chair, Laboratory Medicine
- Chief, Laboratory Medicine
Education & Training
- FellowBrigham & Women's Hospital/Dana Farber Cancer Center/Children's Hospital,Boston (1982)
- ResidentBrigham & Women's Hospital/Harvard Medical School (1978)
- MDHarvard University (1976)
- BAPrinceton University, Chemistry (1972)
Additional Information
Honors & Recognitions
- Evans Award for Outstanding Contributions to Laboratory Medicine: Academy of Clinical Laboratory Physicians & Scientists (2010)
- Chair (elected), Research Committee and Member of the Council: Association of Pathology Chairs (2010)
- President, Academy of Clinical Laboratory Physicians & Scientists: Academy of Clinical Laboratory Physicians & Scientists (2007), (2008)
Board Certifications
- AB of Pathology, Hematology (Pathology) (1999)
- AB of Internal Medicine, Medical Oncology (1981)
- AB of Internal Medicine, Hematology (Internal Medicine) (1980)
- AB of Internal Medicine, Internal Medicine (1979)
Publications
- Smith BR, Kamoun M, Hickner J. Laboratory Medicine Education at U.S. Medical Schools: A 2014 Status Report. Academic Medicine : Journal Of The Association Of American Medical Colleges 2016, 91: 107-12. PMID: 26200574, PMCID: PMC5480607, DOI: 10.1097/ACM.0000000000000817.
- Ziai JM, Smith BR. Pathology resident and fellow education in a time of disruptive technologies. Clinics In Laboratory Medicine 2012, 32: 623-38. PMID: 23078663, DOI: 10.1016/j.cll.2012.07.004.
- Smith BR, Aguero-Rosenfeld M, Anastasi J, Baron B, Berg A, Bock JL, Campbell S, Crookston KP, Fitzgerald R, Fung M, Haspel R, Howe JG, Jhang J, Kamoun M, Koethe S, Krasowski MD, Landry ML, Marques MB, Rinder HM, Roberts W, Schreiber WE, Spitalnik SL, Tormey CA, Wolf P, Wu YY. Educating medical students in laboratory medicine: a proposed curriculum. American Journal Of Clinical Pathology 2010, 133: 533-42. PMID: 20231605, DOI: 10.1309/AJCPQCT94SFERLNI.
- Remick DG, Lorenz RG, Smith BR. Opportunity: Newly Created Physician-Scientist Research Pathway by the American Board of Pathology. Academic Pathology 2016, 3: 2374289516632240. PMID: 28725759, PMCID: PMC5497862, DOI: 10.1177/2374289516632240.
- Rifai N, Smith BR, Connelly MT. A Message to Medical School Promotion Committees: Proper Credit for Peer-Reviewed Online Educational Materials. Clinical Chemistry 2019, 65: 715-717. PMID: 31003977, DOI: 10.1373/clinchem.2019.305862.
- Tormey CA, Smith BR. The transfusion medicine specialist as a coagulation consultant: a new variant of therapeutic pathology. Transfusion 2013, 53: 2086-93. PMID: 23228202, DOI: 10.1111/trf.12012.
- Smith BR. Therapeutic pathology: time to move beyond diagnostics. Human Pathology 2008, 39: 1725-7. PMID: 18656233, DOI: 10.1016/j.humpath.2008.04.004.
- Schulz WL, Rinder HM, Durant TJS, Tormey CA, Torres R, Smith BR, Hager KM, Howe JG, Siddon AJ. Impact of intra-tumoral heterogeneity detected by next-generation sequencing on acute myeloid leukemia survival. Leukemia & Lymphoma 2020, 61: 3269-3271. PMID: 32715805, DOI: 10.1080/10428194.2020.1797016.
- Chen PP, Tormey CA, Eisenbarth SC, Torres R, Richardson SS, Rinder HM, Smith BR, Siddon AJ. False-Positive Light Chain Clonal Restriction by Flow Cytometry in Patients Treated With Alemtuzumab: Potential Pitfalls for the Misdiagnosis of B-Cell Neoplasms. American Journal Of Clinical Pathology 2019, 151: 154-163. PMID: 30307483, DOI: 10.1093/ajcp/aqy129.
- Abi-Raad R, Smith BR. Biosimilar biologics: never identical but close enough. Transfusion 2015, 55: 229-31. PMID: 25683185, DOI: 10.1111/trf.12961.
- Scott MG, Smith BR, Wu AH, Young IS, Plebani M, Chiu RW. How well are we training the next generation of clinical pathologists and clinical laboratory directors? A global perspective. Clinical Chemistry 2012, 58: 491-5. PMID: 21969387, DOI: 10.1373/clinchem.2011.171199.
- Wells A, Smith BR. The goals of resident training in laboratory medicine in combined anatomic pathology/clinical pathology programs: an overview. Clinics In Laboratory Medicine 2007, 27: 229-40; abstract v. PMID: 17556082, DOI: 10.1016/j.cll.2007.03.001.
- Smith BR, Wells A, Alexander CB, Bovill E, Campbell S, Dasgupta A, Fung M, Haller B, Howe JG, Parvin C, Peerschke E, Rinder H, Spitalnik S, Weiss R, Wener M. Curriculum content and evaluation of resident competency in clinical pathology (laboratory medicine): a proposal. Clinical Chemistry 2006, 52: 917-49. PMID: 16569705, DOI: 10.1373/clinchem.2005.066076.
- Ross G, Erickson R, Knorr D, Motulsky AG, Parkman R, Samulski J, Straus SE, Smith BR. Gene therapy in the United States: a five-year status report. Human Gene Therapy 1996, 7: 1781-90. PMID: 8886849, DOI: 10.1089/hum.1996.7.14-1781.
- Smith BR. Can medical rationing be made rational? Archives Of Internal Medicine 1992, 152: 476-7. PMID: 1546908.
- Smith BR. Flow cytometric analysis of circulating lymphocytes following human marrow transplantation. Cytometry. Supplement : The Journal Of The Society For Analytical Cytology 1988, 3: 48-51. PMID: 3076367.
- Smith BR, Weinberg DS, Robert NJ, Towle M, Luther E, Pinkus GS, Ault KA. Circulating monoclonal B lymphocytes in non-Hodgkin's lymphoma. The New England Journal Of Medicine 1984, 311: 1476-81. PMID: 6438505, DOI: 10.1056/NEJM198412063112304.
Patient Care Organizations
Titles
- Professor of Laboratory Medicine, of Biomedical Engineering, of Medicine (Hematology) and of Pediatrics
- Deputy Dean for Research, (Clinical and Translational)
- Co-Director, Yale Center for Clinical Investigation (YCCI)
- Director, Clinical Immunology Laboratory, Laboratory Medicine
- Chair, Laboratory Medicine
- Chief, Laboratory Medicine
Education & Training
- FellowBrigham & Women's Hospital/Dana Farber Cancer Center/Children's Hospital,Boston (1982)
- ResidentBrigham & Women's Hospital/Harvard Medical School (1978)
- MDHarvard University (1976)
- BAPrinceton University, Chemistry (1972)
Additional Information
Honors & Recognitions
- Evans Award for Outstanding Contributions to Laboratory Medicine: Academy of Clinical Laboratory Physicians & Scientists (2010)
- Chair (elected), Research Committee and Member of the Council: Association of Pathology Chairs (2010)
- President, Academy of Clinical Laboratory Physicians & Scientists: Academy of Clinical Laboratory Physicians & Scientists (2007), (2008)
Board Certifications
- AB of Pathology, Hematology (Pathology) (1999)
- AB of Internal Medicine, Medical Oncology (1981)
- AB of Internal Medicine, Hematology (Internal Medicine) (1980)
- AB of Internal Medicine, Internal Medicine (1979)
Publications
- Smith BR, Kamoun M, Hickner J. Laboratory Medicine Education at U.S. Medical Schools: A 2014 Status Report. Academic Medicine : Journal Of The Association Of American Medical Colleges 2016, 91: 107-12. PMID: 26200574, PMCID: PMC5480607, DOI: 10.1097/ACM.0000000000000817.
- Ziai JM, Smith BR. Pathology resident and fellow education in a time of disruptive technologies. Clinics In Laboratory Medicine 2012, 32: 623-38. PMID: 23078663, DOI: 10.1016/j.cll.2012.07.004.
- Smith BR, Aguero-Rosenfeld M, Anastasi J, Baron B, Berg A, Bock JL, Campbell S, Crookston KP, Fitzgerald R, Fung M, Haspel R, Howe JG, Jhang J, Kamoun M, Koethe S, Krasowski MD, Landry ML, Marques MB, Rinder HM, Roberts W, Schreiber WE, Spitalnik SL, Tormey CA, Wolf P, Wu YY. Educating medical students in laboratory medicine: a proposed curriculum. American Journal Of Clinical Pathology 2010, 133: 533-42. PMID: 20231605, DOI: 10.1309/AJCPQCT94SFERLNI.
- Remick DG, Lorenz RG, Smith BR. Opportunity: Newly Created Physician-Scientist Research Pathway by the American Board of Pathology. Academic Pathology 2016, 3: 2374289516632240. PMID: 28725759, PMCID: PMC5497862, DOI: 10.1177/2374289516632240.
- Rifai N, Smith BR, Connelly MT. A Message to Medical School Promotion Committees: Proper Credit for Peer-Reviewed Online Educational Materials. Clinical Chemistry 2019, 65: 715-717. PMID: 31003977, DOI: 10.1373/clinchem.2019.305862.
- Tormey CA, Smith BR. The transfusion medicine specialist as a coagulation consultant: a new variant of therapeutic pathology. Transfusion 2013, 53: 2086-93. PMID: 23228202, DOI: 10.1111/trf.12012.
- Smith BR. Therapeutic pathology: time to move beyond diagnostics. Human Pathology 2008, 39: 1725-7. PMID: 18656233, DOI: 10.1016/j.humpath.2008.04.004.
- Schulz WL, Rinder HM, Durant TJS, Tormey CA, Torres R, Smith BR, Hager KM, Howe JG, Siddon AJ. Impact of intra-tumoral heterogeneity detected by next-generation sequencing on acute myeloid leukemia survival. Leukemia & Lymphoma 2020, 61: 3269-3271. PMID: 32715805, DOI: 10.1080/10428194.2020.1797016.
- Chen PP, Tormey CA, Eisenbarth SC, Torres R, Richardson SS, Rinder HM, Smith BR, Siddon AJ. False-Positive Light Chain Clonal Restriction by Flow Cytometry in Patients Treated With Alemtuzumab: Potential Pitfalls for the Misdiagnosis of B-Cell Neoplasms. American Journal Of Clinical Pathology 2019, 151: 154-163. PMID: 30307483, DOI: 10.1093/ajcp/aqy129.
- Abi-Raad R, Smith BR. Biosimilar biologics: never identical but close enough. Transfusion 2015, 55: 229-31. PMID: 25683185, DOI: 10.1111/trf.12961.
- Scott MG, Smith BR, Wu AH, Young IS, Plebani M, Chiu RW. How well are we training the next generation of clinical pathologists and clinical laboratory directors? A global perspective. Clinical Chemistry 2012, 58: 491-5. PMID: 21969387, DOI: 10.1373/clinchem.2011.171199.
- Wells A, Smith BR. The goals of resident training in laboratory medicine in combined anatomic pathology/clinical pathology programs: an overview. Clinics In Laboratory Medicine 2007, 27: 229-40; abstract v. PMID: 17556082, DOI: 10.1016/j.cll.2007.03.001.
- Smith BR, Wells A, Alexander CB, Bovill E, Campbell S, Dasgupta A, Fung M, Haller B, Howe JG, Parvin C, Peerschke E, Rinder H, Spitalnik S, Weiss R, Wener M. Curriculum content and evaluation of resident competency in clinical pathology (laboratory medicine): a proposal. Clinical Chemistry 2006, 52: 917-49. PMID: 16569705, DOI: 10.1373/clinchem.2005.066076.
- Ross G, Erickson R, Knorr D, Motulsky AG, Parkman R, Samulski J, Straus SE, Smith BR. Gene therapy in the United States: a five-year status report. Human Gene Therapy 1996, 7: 1781-90. PMID: 8886849, DOI: 10.1089/hum.1996.7.14-1781.
- Smith BR. Can medical rationing be made rational? Archives Of Internal Medicine 1992, 152: 476-7. PMID: 1546908.
- Smith BR. Flow cytometric analysis of circulating lymphocytes following human marrow transplantation. Cytometry. Supplement : The Journal Of The Society For Analytical Cytology 1988, 3: 48-51. PMID: 3076367.
- Smith BR, Weinberg DS, Robert NJ, Towle M, Luther E, Pinkus GS, Ault KA. Circulating monoclonal B lymphocytes in non-Hodgkin's lymphoma. The New England Journal Of Medicine 1984, 311: 1476-81. PMID: 6438505, DOI: 10.1056/NEJM198412063112304.
Patient Care Organizations