- Yale New Haven Hospital20 York StreetNew Haven, CT 06510
Aymen Alian, MBChB, MD, MSc, MBBCh
Biography
Aymen Alian, MBChB (a medical degree awarded outside the U.S.), is an anesthesiologist who specializes in obstetric and gynecological anesthesiology.
Dr. Alian is an associate professor of anesthesiology at Yale School of Medicine and interim division chief for obstetrics and gynecologic anesthesiology. He studies cardiopulmonary and autonomic physiology and uses non-invasive monitors to detect central hypovolemia, a condition where there is decreased blood volume in the central circulatory system, during surgical procedures. Dr. Alian earned his medical degree from Zagazig University in Egypt. He completed his residency in anesthesiology at Yale New Haven Hospital and an internship at Griffin Hospital.
Titles
- Associate Professor of Anesthesiology
- Division Chief, Obstetric & Gynecological Anesthesiology
Education & Training
- MBChBZagazig University (1991)
Additional Information
- AB of Anesthesiology, Anesthesiology (2009)
- Elgendi M, Chen J, Xiao X, Yin J, Paez-Granados D, Menon C, Riener R, Allen J, Pineda-Alpízar A, Zheng D, Easthope C, Gnarra O, Lazaro J, Gil E, Bailon R, Laguna P, Guo X, Chan R, Cheung V, Cheung R, Wei Y, Aboagye S, Sasagaki K, Ali A, Hunt J, Akerman H, White N, Massaroni C, Schena E, Alsaafeen N, Fatma B, Pitsalidis C, Pappa A, Yang W, Ahmadizadeh C, Galli V, Hannigan B, Li Y, Shokurov A, Kim S, Luo S, Chan V, Truong V, Baker S, Papale L, Philippa B, Alberto Cruz-Castaneda W, Bertemes-Filho P, Borik S, Alian A, Tom N, Yuce M, Markov K, Islam S, Dunn J, Franklin D, Williams J, Lovell N, Alinejad-Rokny H, Argha A, Dheman K, Wagih M, Goltay M, Liu H, Albagdady A, Dave D, Akbulut E, Vinella D, Carlini A, Steinhubl S, Dickey M. The 2026 global roadmap for textile-integrated wearable technologies in health. Physiological Measurement 2026 PMID: 42392179, DOI: 10.1088/1361-6579/ae85b0.
- Elgendi M, Li S, Menon C, Lam E, Al-Omari B, Borik S, Shelley K, Alian A. Roadmap of remote photoplethysmography from heart rate measurement toward clinical translation. Npj Digital Medicine 2026 PMID: 42106569, DOI: 10.1038/s41746-026-02715-1.
- Borik S, Zemanikova M, Procka P, Seleng J, Labuda M, Alian A. Photoplethysmography imaging reveals frequency-specific microvascular responses to histamine in human skin. Computers In Biology And Medicine 2026, 202: 111464. PMID: 41520475, DOI: 10.1016/j.compbiomed.2026.111464.
- Woolcock H, Katsidoniotaki M, Meng L, Haghighi N, van Wingerden A, Alian A, Booker W, Bello N, Marshall R, Kougioumtzoglou I, Petersen N, Miller E. Aggregated postpartum cerebral autoregulatory curves in normotensive individuals, preeclampsia with severe features, and superimposed preeclampsia with severe features. Physiological Measurement 2025, 46: 09nt01. PMID: 40845907, PMCID: PMC12441783, DOI: 10.1088/1361-6579/adfeb4.
- Chand S, Chiu N, Chou Y, Alian A, Shelley K, Wu H. Comparison of feature-based indices derived from photoplethysmogram recorded from different body locations during lower body negative pressure. Physiological Measurement 2025, 46: 085002. PMID: 40712634, DOI: 10.1088/1361-6579/adf489.
- Anakmeteeprugsa S, Gonzalez-Fiol A, Garay A, Lin H, He Z, Alian A. Baseline values for Quantra® QPlus® in healthy pregnant women at term and comparison to standard laboratory coagulation values: a prospective observational study. BMC Pregnancy And Childbirth 2025, 25: 826. PMID: 40781663, PMCID: PMC12333236, DOI: 10.1186/s12884-025-07927-z.
- Borik S, Gilmore M, Gonzales-Fiol A, Biondi J, Wu H, Shelley K, Alian A. Photoplethysmography imaging to assess facial perfusion under simulated hypovolemia. Physiological Measurement 2025, 46: 075008. PMID: 40623433, DOI: 10.1088/1361-6579/adece3.
- Gonzalez Fiol A, Pawan F, Alian A. Spinal Sonography for Ultrasound-Guided Lumbar Neuraxial Anesthesia. Journal Of Visualized Experiments 2025 PMID: 39960192, DOI: 10.3791/66901.
- Bhutani S, Alian A, Fletcher R, Bomberg H, Eichenberger U, Menon C, Elgendi M. Vital signs-based healthcare kiosks for screening chronic and infectious diseases: a systematic review. Communications Medicine 2025, 5: 28. PMID: 39837977, PMCID: PMC11751283, DOI: 10.1038/s43856-025-00738-5.
- Fiol A, McGuire P, Fardelmann K, Alian A. Chapter 20 Postoperative pain management for cesarean delivery. 2025, 213-221. DOI: 10.1016/b978-0-443-21707-4.00020-3.
- Elgendi M, Jost E, Alian A, Fletcher R, Bomberg H, Eichenberger U, Menon C. Photoplethysmography Features Correlated with Blood Pressure Changes. Diagnostics 2024, 14: 2309. PMID: 39451632, PMCID: PMC11506471, DOI: 10.3390/diagnostics14202309.
- van Wingerden A, Katsidoniotaki M, Haghighi N, Almonte C, Martinez H, Valdes E, Castro P, Alian A, Booker W, Bello N, Marshall R, Kougioumtzoglou I, Petersen N, Miller E. Postpartum Blood Pressure Variability and Heart Rate Variability in Preeclampsia. Hypertension 2024, 81: 2510-2519. PMID: 39403810, PMCID: PMC11578794, DOI: 10.1161/hypertensionaha.124.23321.
- Borik S, Wu H, Shelley K, Alian A. Graph connection Laplacian allows for enhanced outcomes of consumer camera based photoplethysmography imaging. Biomedical Signal Processing And Control 2024, 96: 106574. DOI: 10.1016/j.bspc.2024.106574.
- Su B, Lee J, Alian A, Calvert J. Renal and Hepatic Pathophysiology of Pregnancy. 2024, 67-72. DOI: 10.1007/978-3-031-62756-9_9.
- Elgendi M, Haugg F, Fletcher R, Allen J, Shin H, Alian A, Menon C. Recommendations for evaluating photoplethysmography-based algorithms for blood pressure assessment. Communications Medicine 2024, 4: 140. PMID: 38997447, PMCID: PMC11245506, DOI: 10.1038/s43856-024-00555-2.
- Fiol A, Rodriguez P, Zhao X, Gaiser R, Herrera A, Alian A. A Prospective Cohort Study to Evaluate Needle Passes Using a Portable Ultrasound Device versus Traditional Landmark Approach for Epidural Anesthesia in a Busy Obstetric Tertiary Care Center. POCUS Journal 2023, 8: 153-158. PMID: 38099155, PMCID: PMC10721287, DOI: 10.24908/pocus.v8i2.16298.
- Anakmeteeprugsa S, Gonzalez-Fiol A, Vychodil R, Shelley K, Alian A. Assessment of changes in blood volume during lower body negative pressure-induced hypovolemia using bioelectrical impedance analysis. Journal Of Clinical Monitoring And Computing 2023, 38: 293-299. PMID: 37966562, DOI: 10.1007/s10877-023-01098-y.
- Chiu N, Chuang B, Anakmeteeprugsa S, Shelley K, Alian A, Wu H. Signal quality assessment of peripheral venous pressure. Journal Of Clinical Monitoring And Computing 2023, 38: 101-112. PMID: 37917210, DOI: 10.1007/s10877-023-01071-9.
- Ackerman-Banks C, Bhinder J, Eder M, Heerdt P, Sugeng L, Testani J, Alian A, Lipkind H, Velazquez E, Reddy U, Chou J. Continuous non-invasive hemodynamic monitoring in early onset severe preeclampsia. Pregnancy Hypertension 2023, 34: 27-32. PMID: 37783090, DOI: 10.1016/j.preghy.2023.09.003.
- Fiol A, Yoo J, Yanez D, Fardelmann K, Salimi N, Alian M, Mancini P, Alian A. Baseline rotational thromboelastometry (ROTEM) values in a healthy, diverse obstetric population and parameter changes by pregnancy-induced comorbidities. Baylor University Medical Center Proceedings 2023, 36: 562-571. PMID: 37614857, PMCID: PMC10443986, DOI: 10.1080/08998280.2023.2217534.
- Eid A, Elgamal M, Gonzalez-Fiol A, Shelley K, Wu H, Alian A. Using the ear photoplethysmographic waveform as an early indicator of central hypovolemia in healthy volunteers utilizing LBNP induced hypovolemia model. Physiological Measurement 2023, 44: 055008. PMID: 37116503, DOI: 10.1088/1361-6579/acd165.
- Salimi N, Gonzalez-Fiol A, Yanez N, Fardelmann K, Harmon E, Kohari K, Abdel-Razeq S, Magriples U, Alian A. Ultrasound Image Quality Comparison Between a Handheld Ultrasound Transducer and Mid-Range Ultrasound Machine. POCUS Journal 2022, 7: 154-159. PMID: 36896280, PMCID: PMC9979954, DOI: 10.24908/pocus.v7i1.15052.
- Alian A, Shelley K. 10 PPG in clinical monitoring. 2022, 341-359. DOI: 10.1016/b978-0-12-823374-0.00006-2.
- Alian A, Lo Y, Shelley K, Wu H. Reconsider phase reconstruction in signals with dynamic periodicity from the modern signal processing perspective. Foundations Of Data Science 2022, 4: 355-393. DOI: 10.3934/fods.2022010.
- Fiol A, Eid A, Yassin Elgamal M, Matlin H, Fardelmann K, Yanez D, Garay A, Alian A. Is There A Role for Liposomal Bupivacaine as Part of a Multimodal Strategy Inclusive of Intrathecal Morphine for Post-Cesarean Analgesia? A Retrospective Chart Review Study. Anesthesia & Pain Research 2020, 4 DOI: 10.33425/2639-846x.1041.
- Alian A, Shelley K. Photoplethysmography: Analysis of the Pulse Oximeter Waveform. 2013, 165-178. DOI: 10.1007/978-1-4614-8557-5_19.
- Alian A, Shelley K. Understanding Anesthesia Equipment, 5th Edition. Anesthesiology 2008, 109: 754-755. DOI: 10.1097/aln.0b013e3181863209.
- Yale New Haven Hospital20 York StreetNew Haven, CT 06510
Biography
Aymen Alian, MBChB (a medical degree awarded outside the U.S.), is an anesthesiologist who specializes in obstetric and gynecological anesthesiology.
Dr. Alian is an associate professor of anesthesiology at Yale School of Medicine and interim division chief for obstetrics and gynecologic anesthesiology. He studies cardiopulmonary and autonomic physiology and uses non-invasive monitors to detect central hypovolemia, a condition where there is decreased blood volume in the central circulatory system, during surgical procedures. Dr. Alian earned his medical degree from Zagazig University in Egypt. He completed his residency in anesthesiology at Yale New Haven Hospital and an internship at Griffin Hospital.
Titles
- Associate Professor of Anesthesiology
- Division Chief, Obstetric & Gynecological Anesthesiology
Education & Training
- MBChBZagazig University (1991)
Additional Information
- AB of Anesthesiology, Anesthesiology (2009)
- Elgendi M, Chen J, Xiao X, Yin J, Paez-Granados D, Menon C, Riener R, Allen J, Pineda-Alpízar A, Zheng D, Easthope C, Gnarra O, Lazaro J, Gil E, Bailon R, Laguna P, Guo X, Chan R, Cheung V, Cheung R, Wei Y, Aboagye S, Sasagaki K, Ali A, Hunt J, Akerman H, White N, Massaroni C, Schena E, Alsaafeen N, Fatma B, Pitsalidis C, Pappa A, Yang W, Ahmadizadeh C, Galli V, Hannigan B, Li Y, Shokurov A, Kim S, Luo S, Chan V, Truong V, Baker S, Papale L, Philippa B, Alberto Cruz-Castaneda W, Bertemes-Filho P, Borik S, Alian A, Tom N, Yuce M, Markov K, Islam S, Dunn J, Franklin D, Williams J, Lovell N, Alinejad-Rokny H, Argha A, Dheman K, Wagih M, Goltay M, Liu H, Albagdady A, Dave D, Akbulut E, Vinella D, Carlini A, Steinhubl S, Dickey M. The 2026 global roadmap for textile-integrated wearable technologies in health. Physiological Measurement 2026 PMID: 42392179, DOI: 10.1088/1361-6579/ae85b0.
- Elgendi M, Li S, Menon C, Lam E, Al-Omari B, Borik S, Shelley K, Alian A. Roadmap of remote photoplethysmography from heart rate measurement toward clinical translation. Npj Digital Medicine 2026 PMID: 42106569, DOI: 10.1038/s41746-026-02715-1.
- Borik S, Zemanikova M, Procka P, Seleng J, Labuda M, Alian A. Photoplethysmography imaging reveals frequency-specific microvascular responses to histamine in human skin. Computers In Biology And Medicine 2026, 202: 111464. PMID: 41520475, DOI: 10.1016/j.compbiomed.2026.111464.
- Woolcock H, Katsidoniotaki M, Meng L, Haghighi N, van Wingerden A, Alian A, Booker W, Bello N, Marshall R, Kougioumtzoglou I, Petersen N, Miller E. Aggregated postpartum cerebral autoregulatory curves in normotensive individuals, preeclampsia with severe features, and superimposed preeclampsia with severe features. Physiological Measurement 2025, 46: 09nt01. PMID: 40845907, PMCID: PMC12441783, DOI: 10.1088/1361-6579/adfeb4.
- Chand S, Chiu N, Chou Y, Alian A, Shelley K, Wu H. Comparison of feature-based indices derived from photoplethysmogram recorded from different body locations during lower body negative pressure. Physiological Measurement 2025, 46: 085002. PMID: 40712634, DOI: 10.1088/1361-6579/adf489.
- Anakmeteeprugsa S, Gonzalez-Fiol A, Garay A, Lin H, He Z, Alian A. Baseline values for Quantra® QPlus® in healthy pregnant women at term and comparison to standard laboratory coagulation values: a prospective observational study. BMC Pregnancy And Childbirth 2025, 25: 826. PMID: 40781663, PMCID: PMC12333236, DOI: 10.1186/s12884-025-07927-z.
- Borik S, Gilmore M, Gonzales-Fiol A, Biondi J, Wu H, Shelley K, Alian A. Photoplethysmography imaging to assess facial perfusion under simulated hypovolemia. Physiological Measurement 2025, 46: 075008. PMID: 40623433, DOI: 10.1088/1361-6579/adece3.
- Gonzalez Fiol A, Pawan F, Alian A. Spinal Sonography for Ultrasound-Guided Lumbar Neuraxial Anesthesia. Journal Of Visualized Experiments 2025 PMID: 39960192, DOI: 10.3791/66901.
- Bhutani S, Alian A, Fletcher R, Bomberg H, Eichenberger U, Menon C, Elgendi M. Vital signs-based healthcare kiosks for screening chronic and infectious diseases: a systematic review. Communications Medicine 2025, 5: 28. PMID: 39837977, PMCID: PMC11751283, DOI: 10.1038/s43856-025-00738-5.
- Fiol A, McGuire P, Fardelmann K, Alian A. Chapter 20 Postoperative pain management for cesarean delivery. 2025, 213-221. DOI: 10.1016/b978-0-443-21707-4.00020-3.
- Elgendi M, Jost E, Alian A, Fletcher R, Bomberg H, Eichenberger U, Menon C. Photoplethysmography Features Correlated with Blood Pressure Changes. Diagnostics 2024, 14: 2309. PMID: 39451632, PMCID: PMC11506471, DOI: 10.3390/diagnostics14202309.
- van Wingerden A, Katsidoniotaki M, Haghighi N, Almonte C, Martinez H, Valdes E, Castro P, Alian A, Booker W, Bello N, Marshall R, Kougioumtzoglou I, Petersen N, Miller E. Postpartum Blood Pressure Variability and Heart Rate Variability in Preeclampsia. Hypertension 2024, 81: 2510-2519. PMID: 39403810, PMCID: PMC11578794, DOI: 10.1161/hypertensionaha.124.23321.
- Borik S, Wu H, Shelley K, Alian A. Graph connection Laplacian allows for enhanced outcomes of consumer camera based photoplethysmography imaging. Biomedical Signal Processing And Control 2024, 96: 106574. DOI: 10.1016/j.bspc.2024.106574.
- Su B, Lee J, Alian A, Calvert J. Renal and Hepatic Pathophysiology of Pregnancy. 2024, 67-72. DOI: 10.1007/978-3-031-62756-9_9.
- Elgendi M, Haugg F, Fletcher R, Allen J, Shin H, Alian A, Menon C. Recommendations for evaluating photoplethysmography-based algorithms for blood pressure assessment. Communications Medicine 2024, 4: 140. PMID: 38997447, PMCID: PMC11245506, DOI: 10.1038/s43856-024-00555-2.
- Fiol A, Rodriguez P, Zhao X, Gaiser R, Herrera A, Alian A. A Prospective Cohort Study to Evaluate Needle Passes Using a Portable Ultrasound Device versus Traditional Landmark Approach for Epidural Anesthesia in a Busy Obstetric Tertiary Care Center. POCUS Journal 2023, 8: 153-158. PMID: 38099155, PMCID: PMC10721287, DOI: 10.24908/pocus.v8i2.16298.
- Anakmeteeprugsa S, Gonzalez-Fiol A, Vychodil R, Shelley K, Alian A. Assessment of changes in blood volume during lower body negative pressure-induced hypovolemia using bioelectrical impedance analysis. Journal Of Clinical Monitoring And Computing 2023, 38: 293-299. PMID: 37966562, DOI: 10.1007/s10877-023-01098-y.
- Chiu N, Chuang B, Anakmeteeprugsa S, Shelley K, Alian A, Wu H. Signal quality assessment of peripheral venous pressure. Journal Of Clinical Monitoring And Computing 2023, 38: 101-112. PMID: 37917210, DOI: 10.1007/s10877-023-01071-9.
- Ackerman-Banks C, Bhinder J, Eder M, Heerdt P, Sugeng L, Testani J, Alian A, Lipkind H, Velazquez E, Reddy U, Chou J. Continuous non-invasive hemodynamic monitoring in early onset severe preeclampsia. Pregnancy Hypertension 2023, 34: 27-32. PMID: 37783090, DOI: 10.1016/j.preghy.2023.09.003.
- Fiol A, Yoo J, Yanez D, Fardelmann K, Salimi N, Alian M, Mancini P, Alian A. Baseline rotational thromboelastometry (ROTEM) values in a healthy, diverse obstetric population and parameter changes by pregnancy-induced comorbidities. Baylor University Medical Center Proceedings 2023, 36: 562-571. PMID: 37614857, PMCID: PMC10443986, DOI: 10.1080/08998280.2023.2217534.
- Eid A, Elgamal M, Gonzalez-Fiol A, Shelley K, Wu H, Alian A. Using the ear photoplethysmographic waveform as an early indicator of central hypovolemia in healthy volunteers utilizing LBNP induced hypovolemia model. Physiological Measurement 2023, 44: 055008. PMID: 37116503, DOI: 10.1088/1361-6579/acd165.
- Salimi N, Gonzalez-Fiol A, Yanez N, Fardelmann K, Harmon E, Kohari K, Abdel-Razeq S, Magriples U, Alian A. Ultrasound Image Quality Comparison Between a Handheld Ultrasound Transducer and Mid-Range Ultrasound Machine. POCUS Journal 2022, 7: 154-159. PMID: 36896280, PMCID: PMC9979954, DOI: 10.24908/pocus.v7i1.15052.
- Alian A, Shelley K. 10 PPG in clinical monitoring. 2022, 341-359. DOI: 10.1016/b978-0-12-823374-0.00006-2.
- Alian A, Lo Y, Shelley K, Wu H. Reconsider phase reconstruction in signals with dynamic periodicity from the modern signal processing perspective. Foundations Of Data Science 2022, 4: 355-393. DOI: 10.3934/fods.2022010.
- Fiol A, Eid A, Yassin Elgamal M, Matlin H, Fardelmann K, Yanez D, Garay A, Alian A. Is There A Role for Liposomal Bupivacaine as Part of a Multimodal Strategy Inclusive of Intrathecal Morphine for Post-Cesarean Analgesia? A Retrospective Chart Review Study. Anesthesia & Pain Research 2020, 4 DOI: 10.33425/2639-846x.1041.
- Alian A, Shelley K. Photoplethysmography: Analysis of the Pulse Oximeter Waveform. 2013, 165-178. DOI: 10.1007/978-1-4614-8557-5_19.
- Alian A, Shelley K. Understanding Anesthesia Equipment, 5th Edition. Anesthesiology 2008, 109: 754-755. DOI: 10.1097/aln.0b013e3181863209.
- Yale New Haven Hospital20 York StreetNew Haven, CT 06510
- Yale New Haven Hospital20 York StreetNew Haven, CT 06510