Gretchen Hermes, MD, PhD
Psychiatry, Addiction Medicine
Titles
- Associate Professor of Psychiatry
- Medical Director, APT Foundation
- Chief Psychiatrist, Yale Stress Center
- Addiction Psychiatry Fellowship Coordinator, APT Foundation
Education & Training
- Research Fellowship, SchizophreniaYale University (2013)
- ResidencyYale University (2011)
- MDUniversity of Chicago Pritzker School of Medicine (2007)
- Postdoctoral Fellowship, NIH, Interdisciplinary Program in ImmunologyUniversity of Chicago (2005)
- PhDUniversity of Chicago (2003)
- MAHarvard Divinity School (1997)
Languages Spoken
- English
- Français (French)
Additional Information
Honors & Recognitions
- NARSAD Young Investigator Grant: Brain and Behavior Research Foundation (2015)
- Workshop on Schizophrenia and Related Disorders, Travel Award and Stipend: Cold Spring Harbor Laboratory (2012)
- Daniel X. and Mary Freedman Fellowship in Academic Psychiatry: Freedman Foundation (2011)
- APA-Pfizer M.D., Ph.D. Research Fellowship Award: American Psychiatric Association (2011)
- Power Day Award, Psychiatry, for a resident nominated by 3rd year medical class, who serves as a true role model for Yale medical students : Yale School of Medicine (2011)
- APA-Janssen Resident Psychiatric Research Scholar: American Psychiatric Association (2010)
- Seymour Lustman Award for Outstanding Resident Research: Yale Department of Psychiatry (2009)
- ACNP Travel Award: American College of Neuropsychopharmacology (2008)
Professional Service
- Female Opioid Research and Clinical Experts (FORCE) (2017 - Present): Member
- California Breast Cancer Research Program; University of California, Office of the President (2016 - Present): Peer Review: Grant submissions in response to an Animal Models Initiative to Investigate Concurrent Effects of Environmental Chemicals and Stress Factors on Mammary Cancer
- Ad Hoc Reviewer (2008 - Present): Brain, Behavior, and Immunity; Frontiers: Schizophrenia, Associate Editor; Neuropharmacology; Neuroendocrinology; Neuroscience Letters; Psychoneuroimmunolgy; Psychiatry Research; Sage OPEN Publications; Schizophrenia Research; Schizophrenia Bulletin
Publications
- Louie D, Jegede O, Hermes G. Chronic use of benzodiazepines: The problem that persists. The International Journal Of Psychiatry In Medicine 2023, 58: 426-432. PMID: 36972700, DOI: 10.1177/00912174231166252.
- Hermes G. Martha K. McClintock. 2022, 359-383. DOI: 10.1007/978-3-031-12970-4_36.
- Milivojevic V, Sullivan L, Tiber J, Fogelman N, Simpson C, Hermes G, Sinha R. Pregnenolone effects on provoked alcohol craving, anxiety, HPA axis, and autonomic arousal in individuals with alcohol use disorder. Psychopharmacology 2022, 240: 101-114. PMID: 36445398, PMCID: PMC10630889, DOI: 10.1007/s00213-022-06278-3.
- Milivojevic V, Charron L, Fogelman N, Hermes G, Sinha R. Pregnenolone Reduces Stress-Induced Craving, Anxiety, and Autonomic Arousal in Individuals with Cocaine Use Disorder. Biomolecules 2022, 12: 1593. PMID: 36358943, PMCID: PMC9687893, DOI: 10.3390/biom12111593.
- Sinha R, Seo D, Lacadie C, Constable T, Hermes G. 98. Effects of Childhood Maltreatment on Neural and Biobehavioral Biomarkers of Relapse and Recovery in Substance Use Disorders. Biological Psychiatry 2018, 83: s40. DOI: 10.1016/j.biopsych.2018.02.116.
- Hermes G, Sanacora G. Ketamine’s Mechanisms of Rapid Antidepressant Activity: Evidence from Preclinical Studies. 2016, 73-98. DOI: 10.1007/978-3-319-42925-0_6.
- Hermes G, Nagy D, Waterson M, Zsarnovszky A, Varela L, Hajos M, Horvath TL. Role of mitochondrial uncoupling protein-2 (UCP2) in higher brain functions, neuronal plasticity and network oscillation. Molecular Metabolism 2016, 5: 415-421. PMID: 27257601, PMCID: PMC4877662, DOI: 10.1016/j.molmet.2016.04.002.
- Gao XB, Hermes G. Neural plasticity in hypocretin neurons: the basis of hypocretinergic regulation of physiological and behavioral functions in animals. Frontiers In Systems Neuroscience 2015, 9: 142. PMID: 26539086, PMCID: PMC4612503, DOI: 10.3389/fnsys.2015.00142.
- Simon-Areces J, Dietrich MO, Hermes G, Garcia-Segura LM, Arevalo MA, Horvath TL. Ucp2 Induced by Natural Birth Regulates Neuronal Differentiation of the Hippocampus and Related Adult Behavior. PLOS ONE 2012, 7: e42911. PMID: 22905184, PMCID: PMC3414493, DOI: 10.1371/journal.pone.0042911.
- Hill D, Coss C, Dubey J, Wroblewski K, Sautter M, Hosten T, Muñoz-Zanzi C, Mui E, Withers S, Boyer K, Hermes G, Coyne J, Jagdis F, Burnett A, McLeod P, Morton H, Robinson D, McLeod R. Identification of a Sporozoite-Specific Antigen from Toxoplasma gondii. Journal Of Parasitology 2011, 97: 328-337. PMID: 21506817, PMCID: PMC3684278, DOI: 10.1645/ge-2782.1.
- Hermes G, Li N, Duman C, Duman R. Post-weaning chronic social isolation produces profound behavioral dysregulation with decreases in prefrontal cortex synaptic-associated protein expression in female rats. Physiology & Behavior 2010, 104: 354-359. PMID: 21185848, PMCID: PMC3387788, DOI: 10.1016/j.physbeh.2010.12.019.
- Hermes GL, Delgado B, Tretiakova M, Cavigelli SA, Krausz T, Conzen SD, McClintock MK. Social isolation dysregulates endocrine and behavioral stress while increasing malignant burden of spontaneous mammary tumors. Proceedings Of The National Academy Of Sciences Of The United States Of America 2009, 106: 22393-22398. PMID: 20018726, PMCID: PMC2799783, DOI: 10.1073/pnas.0910753106.
- Hermes G, Ajioka JW, Kelly KA, Mui E, Roberts F, Kasza K, Mayr T, Kirisits MJ, Wollmann R, Ferguson D, Roberts CW, Hwang JH, Trendler T, Kennan RP, Suzuki Y, Reardon C, Hickey WF, Chen L, McLeod R. Neurological and behavioral abnormalities, ventricular dilatation, altered cellular functions, inflammation, and neuronal injury in brains of mice due to common, persistent, parasitic infection. Journal Of Neuroinflammation 2008, 5: 48. PMID: 18947414, PMCID: PMC2588578, DOI: 10.1186/1742-2094-5-48.
- Hermes GL, McClintock MK. Isolation and the timing of mammary gland development, gonadarche, and ovarian senescence: Implications for mammary tumor burden. Developmental Psychobiology 2008, 50: 353-360. PMID: 18393277, DOI: 10.1002/dev.20295.
- Hermes GL, Rosenthal L, Montag A, McClintock MK. Social isolation and the inflammatory response: sex differences in the enduring effects of a prior stressor. AJP Regulatory Integrative And Comparative Physiology 2005, 290: r273-r282. PMID: 16210419, DOI: 10.1152/ajpregu.00368.2005.
- Hermes GL, Jacobs LF, McClintock MK. The sectored foraging field: A novel design to quantify spatial strategies, learning, memory, and emotion. Neurobiology Of Learning And Memory 2005, 84: 69-73. PMID: 15936684, DOI: 10.1016/j.nlm.2005.02.001.
- Emotions and Disease Exhibtion Cataloghttps://www.nlm.nih.gov/exhibition/emotions/
Departments and Programs
Titles
- Associate Professor of Psychiatry
- Medical Director, APT Foundation
- Chief Psychiatrist, Yale Stress Center
- Addiction Psychiatry Fellowship Coordinator, APT Foundation
Education & Training
- Research Fellowship, SchizophreniaYale University (2013)
- ResidencyYale University (2011)
- MDUniversity of Chicago Pritzker School of Medicine (2007)
- Postdoctoral Fellowship, NIH, Interdisciplinary Program in ImmunologyUniversity of Chicago (2005)
- PhDUniversity of Chicago (2003)
- MAHarvard Divinity School (1997)
Languages Spoken
- English
- Français (French)
Additional Information
Honors & Recognitions
- NARSAD Young Investigator Grant: Brain and Behavior Research Foundation (2015)
- Workshop on Schizophrenia and Related Disorders, Travel Award and Stipend: Cold Spring Harbor Laboratory (2012)
- Daniel X. and Mary Freedman Fellowship in Academic Psychiatry: Freedman Foundation (2011)
- APA-Pfizer M.D., Ph.D. Research Fellowship Award: American Psychiatric Association (2011)
- Power Day Award, Psychiatry, for a resident nominated by 3rd year medical class, who serves as a true role model for Yale medical students : Yale School of Medicine (2011)
- APA-Janssen Resident Psychiatric Research Scholar: American Psychiatric Association (2010)
- Seymour Lustman Award for Outstanding Resident Research: Yale Department of Psychiatry (2009)
- ACNP Travel Award: American College of Neuropsychopharmacology (2008)
Professional Service
- Female Opioid Research and Clinical Experts (FORCE) (2017 - Present): Member
- California Breast Cancer Research Program; University of California, Office of the President (2016 - Present): Peer Review: Grant submissions in response to an Animal Models Initiative to Investigate Concurrent Effects of Environmental Chemicals and Stress Factors on Mammary Cancer
- Ad Hoc Reviewer (2008 - Present): Brain, Behavior, and Immunity; Frontiers: Schizophrenia, Associate Editor; Neuropharmacology; Neuroendocrinology; Neuroscience Letters; Psychoneuroimmunolgy; Psychiatry Research; Sage OPEN Publications; Schizophrenia Research; Schizophrenia Bulletin
Publications
- Louie D, Jegede O, Hermes G. Chronic use of benzodiazepines: The problem that persists. The International Journal Of Psychiatry In Medicine 2023, 58: 426-432. PMID: 36972700, DOI: 10.1177/00912174231166252.
- Hermes G. Martha K. McClintock. 2022, 359-383. DOI: 10.1007/978-3-031-12970-4_36.
- Milivojevic V, Sullivan L, Tiber J, Fogelman N, Simpson C, Hermes G, Sinha R. Pregnenolone effects on provoked alcohol craving, anxiety, HPA axis, and autonomic arousal in individuals with alcohol use disorder. Psychopharmacology 2022, 240: 101-114. PMID: 36445398, PMCID: PMC10630889, DOI: 10.1007/s00213-022-06278-3.
- Milivojevic V, Charron L, Fogelman N, Hermes G, Sinha R. Pregnenolone Reduces Stress-Induced Craving, Anxiety, and Autonomic Arousal in Individuals with Cocaine Use Disorder. Biomolecules 2022, 12: 1593. PMID: 36358943, PMCID: PMC9687893, DOI: 10.3390/biom12111593.
- Sinha R, Seo D, Lacadie C, Constable T, Hermes G. 98. Effects of Childhood Maltreatment on Neural and Biobehavioral Biomarkers of Relapse and Recovery in Substance Use Disorders. Biological Psychiatry 2018, 83: s40. DOI: 10.1016/j.biopsych.2018.02.116.
- Hermes G, Sanacora G. Ketamine’s Mechanisms of Rapid Antidepressant Activity: Evidence from Preclinical Studies. 2016, 73-98. DOI: 10.1007/978-3-319-42925-0_6.
- Hermes G, Nagy D, Waterson M, Zsarnovszky A, Varela L, Hajos M, Horvath TL. Role of mitochondrial uncoupling protein-2 (UCP2) in higher brain functions, neuronal plasticity and network oscillation. Molecular Metabolism 2016, 5: 415-421. PMID: 27257601, PMCID: PMC4877662, DOI: 10.1016/j.molmet.2016.04.002.
- Gao XB, Hermes G. Neural plasticity in hypocretin neurons: the basis of hypocretinergic regulation of physiological and behavioral functions in animals. Frontiers In Systems Neuroscience 2015, 9: 142. PMID: 26539086, PMCID: PMC4612503, DOI: 10.3389/fnsys.2015.00142.
- Simon-Areces J, Dietrich MO, Hermes G, Garcia-Segura LM, Arevalo MA, Horvath TL. Ucp2 Induced by Natural Birth Regulates Neuronal Differentiation of the Hippocampus and Related Adult Behavior. PLOS ONE 2012, 7: e42911. PMID: 22905184, PMCID: PMC3414493, DOI: 10.1371/journal.pone.0042911.
- Hill D, Coss C, Dubey J, Wroblewski K, Sautter M, Hosten T, Muñoz-Zanzi C, Mui E, Withers S, Boyer K, Hermes G, Coyne J, Jagdis F, Burnett A, McLeod P, Morton H, Robinson D, McLeod R. Identification of a Sporozoite-Specific Antigen from Toxoplasma gondii. Journal Of Parasitology 2011, 97: 328-337. PMID: 21506817, PMCID: PMC3684278, DOI: 10.1645/ge-2782.1.
- Hermes G, Li N, Duman C, Duman R. Post-weaning chronic social isolation produces profound behavioral dysregulation with decreases in prefrontal cortex synaptic-associated protein expression in female rats. Physiology & Behavior 2010, 104: 354-359. PMID: 21185848, PMCID: PMC3387788, DOI: 10.1016/j.physbeh.2010.12.019.
- Hermes GL, Delgado B, Tretiakova M, Cavigelli SA, Krausz T, Conzen SD, McClintock MK. Social isolation dysregulates endocrine and behavioral stress while increasing malignant burden of spontaneous mammary tumors. Proceedings Of The National Academy Of Sciences Of The United States Of America 2009, 106: 22393-22398. PMID: 20018726, PMCID: PMC2799783, DOI: 10.1073/pnas.0910753106.
- Hermes G, Ajioka JW, Kelly KA, Mui E, Roberts F, Kasza K, Mayr T, Kirisits MJ, Wollmann R, Ferguson D, Roberts CW, Hwang JH, Trendler T, Kennan RP, Suzuki Y, Reardon C, Hickey WF, Chen L, McLeod R. Neurological and behavioral abnormalities, ventricular dilatation, altered cellular functions, inflammation, and neuronal injury in brains of mice due to common, persistent, parasitic infection. Journal Of Neuroinflammation 2008, 5: 48. PMID: 18947414, PMCID: PMC2588578, DOI: 10.1186/1742-2094-5-48.
- Hermes GL, McClintock MK. Isolation and the timing of mammary gland development, gonadarche, and ovarian senescence: Implications for mammary tumor burden. Developmental Psychobiology 2008, 50: 353-360. PMID: 18393277, DOI: 10.1002/dev.20295.
- Hermes GL, Rosenthal L, Montag A, McClintock MK. Social isolation and the inflammatory response: sex differences in the enduring effects of a prior stressor. AJP Regulatory Integrative And Comparative Physiology 2005, 290: r273-r282. PMID: 16210419, DOI: 10.1152/ajpregu.00368.2005.
- Hermes GL, Jacobs LF, McClintock MK. The sectored foraging field: A novel design to quantify spatial strategies, learning, memory, and emotion. Neurobiology Of Learning And Memory 2005, 84: 69-73. PMID: 15936684, DOI: 10.1016/j.nlm.2005.02.001.
- Emotions and Disease Exhibtion Cataloghttps://www.nlm.nih.gov/exhibition/emotions/
Departments and Programs