Diagnosing Lupus Nephritis

This information is useful for adults and older adults
A man with lupus nephritis gripping his ankle on a blue couch.

Lupus nephritis is an autoimmune disease that causes rampant inflammation throughout the body. It can affect the skin, bones, muscles and/or internal organs, including the heart, brain and kidneys. Kidney inflammation can be a sign of severe illness that indicates a need for aggressive treatment, says Yale Medicine pathologist Gilbert Moeckel, MD, PhD. Lupus nephritis (also called lupus kidney disease) is the diagnosis for lupus that has attacked the kidneys.