Zachary Harvanek, MD, PhD
he/him/his
Psychosomatic Medicine, Psychiatry
Telehealth is available
Patient type treated
Adult
Accepting new patients
Yes
Referral required
From physicians only
Board Certified in
Consultation-Liaison Psychiatry
Titles
- Assistant Professor
Education & Training
- Consultation-Liaison Psychiatry FellowYale University (2023)
- ResidentYale University (2022)
- PhDUniversity of Michigan, Molecular & Integrative Physiology (2018)
- MDUniversity of Michigan, Molecular & Integrative Physiology (2018)
- BEngSciDuke University, Biomedical Engineering & Biology (2010)
Additional Information
Honors & Recognitions
- Yale Physician-Scientist Development Award: Yale School of Medicine (2023)
- APA Research Colloquium: American Psychiatric Association (2023)
- William Webb Fellowship: Academy of Consultation-Liaison Psychiatry (2022)
- Seymour Lustman Resident Research Award - 2nd Place: Yale Department of Psychiatry (2022)
- Honors Scholars Program: American Association for Geriatric Psychiatry (2022)
- Early Career Investigator Travel Award: Society of Biological Psychiatry (2021)
- Seymour Lustman Resident Research Award - 1st Place: Yale Department of Psychiatry (2021)
- Outstanding Resident Award Program - Honorable Mention: NIMH (2020)
Board Certifications
- AB of Psychiatry & Neurology, Consultation-Liaison Psychiatry (2023)
Professional Service
- Peer Reviewed Medical Research Program (2024): ad-hoc grant reviewer for study section
- Aging Cell (2024 - Present): Reviewer
- PLOS Computational Biology (2024 - Present): Guest Editor
- Neurobiology of Stress (2023 - Present): Reviewer
- Frontiers in Epigenetics and Epigenomics (2023 - Present): Topic editor for Epigenetic Basis of Circadian Rhythm and Metabolism
- ACLP - Guidelines & Evidence-Based Medicine Subcommittee (2022 - Present): Includes writing quarterly updates for ACLP about new research in psychiatry and aging.
- Epigenomics (2022 - Present): Reviewer
- Developmental Psychology (2022 - Present): Reviewer
- eLife (2021 - Present): Reviewer
- Psychoneuroendrocrinology (2021 - Present): Reviewer
Publications
- Chowdhary A, Holloway T, Xu K, Sinha R, Harvanek Z. Race-Related Differences in Protective Effects of Emotion Regulation Against GrimAge Acceleration Are Driven by Assaultive Trauma. Psychological Trauma Theory Research Practice And Policy 2025 PMID: 40232770, DOI: 10.1037/tra0001888.
- Crusto C, Kaufman J, Harvanek Z, Nelson C, Forray A. Perceptions of Care and Perceived Discrimination: A Qualitative Assessment of Adults Living with Sickle Cell Disease. Journal Of Racial And Ethnic Health Disparities 2024, 1-10. PMID: 39227547, DOI: 10.1007/s40615-024-02153-3.
- Harvanek Z, Kudinova A, Wong S, Xu K, Brick L, Daniels T, Marsit C, Burt A, Sinha R, Tyrka A. Childhood adversity, accelerated GrimAge, and associated health consequences. Journal Of Behavioral Medicine 2024, 47: 913-926. PMID: 38762606, PMCID: PMC11365810, DOI: 10.1007/s10865-024-00496-0.
- Holloway T, Harvanek Z, Xu K, Gordon D, Sinha R. Greater Stress and Trauma Mediate Race-Related Differences in Epigenetic Age Between Black and White Young Adults in a Community Sample. Biological Psychiatry 2024, 95: s41. DOI: 10.1016/j.biopsych.2024.02.104.
- Harvanek Z, Zhang X, Xu K, Sinha R. 353. Methylation of CRHR1 and CRHR2 is Associated With Lifetime Adversity, HPA-Axis Signaling Changes, and Obesity. Biological Psychiatry 2024, 95: s244. DOI: 10.1016/j.biopsych.2024.02.852.
- Holloway T, Harvanek Z, Xu K, Gordon D, Sinha R. Greater stress and trauma mediate race-related differences in epigenetic age between Black and White young adults in a community sample. Neurobiology Of Stress 2023, 26: 100557. PMID: 37501940, PMCID: PMC10369475, DOI: 10.1016/j.ynstr.2023.100557.
- Harvanek Z, Boks M, Vinkers C, Higgins-Chen A. The Cutting Edge of Epigenetic Clocks: In Search of Mechanisms Linking Aging and Mental Health. Biological Psychiatry 2023, 94: 694-705. PMID: 36764569, PMCID: PMC10409884, DOI: 10.1016/j.biopsych.2023.02.001.
- Holloway T, Harvanek Z, Xu K, Gordon D, Sinha R. P75. Stress and Trauma Mediate Some, But Not All, Differences in GrimAge Acceleration Between Black and White Participants in Observed Cohort Study. Biological Psychiatry 2022, 91: s117. DOI: 10.1016/j.biopsych.2022.02.309.
- Harvanek ZM, Fogelman N, Xu K, Sinha R. Psychological and biological resilience modulates the effects of stress on epigenetic aging. Translational Psychiatry 2021, 11: 601. PMID: 34839356, PMCID: PMC8627511, DOI: 10.1038/s41398-021-01735-7.
- Gendron CM, Chakraborty TS, Chung BY, Harvanek ZM, Holme KJ, Johnson JC, Lyu Y, Munneke AS, Pletcher SD. Neuronal Mechanisms that Drive Organismal Aging Through the Lens of Perception. Annual Review Of Physiology 2019, 82: 1-23. PMID: 31635526, PMCID: PMC7012701, DOI: 10.1146/annurev-physiol-021119-034440.
- Harvanek ZM, Millard H. A Structured Approach to Introducing Residents to Group Therapy Leadership. Academic Psychiatry 2019, 43: 652-653. PMID: 31485999, DOI: 10.1007/s40596-019-01112-z.
- Henderson D, Huebner C, Markowitz M, Taube N, Harvanek ZM, Jakob U, Knoefler D. Do developmental temperatures affect redox level and lifespan in C. elegans through upregulation of peroxiredoxin? Redox Biology 2017, 14: 386-390. PMID: 29055282, PMCID: PMC5647470, DOI: 10.1016/j.redox.2017.10.003.
- Harvanek ZM, Lyu Y, Gendron CM, Johnson JC, Kondo S, Promislow DEL, Pletcher SD. Perceptive costs of reproduction drive ageing and physiology in male Drosophila. Nature Ecology & Evolution 2017, 1: 0152. PMID: 28812624, PMCID: PMC5657004, DOI: 10.1038/s41559-017-0152.
- Harvanek ZM, Mourão MA, Schnell S, Pletcher SD. A computational approach to studying ageing at the individual level. Proceedings Of The Royal Society B 2016, 283: 20152346. PMID: 26865300, PMCID: PMC4760160, DOI: 10.1098/rspb.2015.2346.
- Ro J, Harvanek ZM, Pletcher SD. FLIC: High-Throughput, Continuous Analysis of Feeding Behaviors in Drosophila. PLOS ONE 2014, 9: e101107. PMID: 24978054, PMCID: PMC4076220, DOI: 10.1371/journal.pone.0101107.
- Waterson MJ, Chung BY, Harvanek ZM, Ostojic I, Alcedo J, Pletcher SD. Water sensor ppk28 modulates Drosophila lifespan and physiology through AKH signaling. Proceedings Of The National Academy Of Sciences Of The United States Of America 2014, 111: 8137-8142. PMID: 24821805, PMCID: PMC4050545, DOI: 10.1073/pnas.1315461111.
- Gendron CM, Kuo TH, Harvanek ZM, Chung BY, Yew JY, Dierick HA, Pletcher SD. Drosophila Life Span and Physiology Are Modulated by Sexual Perception and Reward. Science 2013, 343: 544-548. PMID: 24292624, PMCID: PMC4042187, DOI: 10.1126/science.1243339.
- Tang W, Dominska M, Greenwell PW, Harvanek Z, Lobachev KS, Kim HM, Narayanan V, Mirkin SM, Petes TD. Friedreich's Ataxia (GAA)n•(TTC)n Repeats Strongly Stimulate Mitotic Crossovers in Saccharomyces cerevisae. PLOS Genetics 2011, 7: e1001270. PMID: 21249181, PMCID: PMC3020933, DOI: 10.1371/journal.pgen.1001270.
Titles
- Assistant Professor
Education & Training
- Consultation-Liaison Psychiatry FellowYale University (2023)
- ResidentYale University (2022)
- PhDUniversity of Michigan, Molecular & Integrative Physiology (2018)
- MDUniversity of Michigan, Molecular & Integrative Physiology (2018)
- BEngSciDuke University, Biomedical Engineering & Biology (2010)
Additional Information
Honors & Recognitions
- Yale Physician-Scientist Development Award: Yale School of Medicine (2023)
- APA Research Colloquium: American Psychiatric Association (2023)
- William Webb Fellowship: Academy of Consultation-Liaison Psychiatry (2022)
- Seymour Lustman Resident Research Award - 2nd Place: Yale Department of Psychiatry (2022)
- Honors Scholars Program: American Association for Geriatric Psychiatry (2022)
- Early Career Investigator Travel Award: Society of Biological Psychiatry (2021)
- Seymour Lustman Resident Research Award - 1st Place: Yale Department of Psychiatry (2021)
- Outstanding Resident Award Program - Honorable Mention: NIMH (2020)
Board Certifications
- AB of Psychiatry & Neurology, Consultation-Liaison Psychiatry (2023)
Professional Service
- Peer Reviewed Medical Research Program (2024): ad-hoc grant reviewer for study section
- Aging Cell (2024 - Present): Reviewer
- PLOS Computational Biology (2024 - Present): Guest Editor
- Neurobiology of Stress (2023 - Present): Reviewer
- Frontiers in Epigenetics and Epigenomics (2023 - Present): Topic editor for Epigenetic Basis of Circadian Rhythm and Metabolism
- ACLP - Guidelines & Evidence-Based Medicine Subcommittee (2022 - Present): Includes writing quarterly updates for ACLP about new research in psychiatry and aging.
- Epigenomics (2022 - Present): Reviewer
- Developmental Psychology (2022 - Present): Reviewer
- eLife (2021 - Present): Reviewer
- Psychoneuroendrocrinology (2021 - Present): Reviewer
Publications
- Chowdhary A, Holloway T, Xu K, Sinha R, Harvanek Z. Race-Related Differences in Protective Effects of Emotion Regulation Against GrimAge Acceleration Are Driven by Assaultive Trauma. Psychological Trauma Theory Research Practice And Policy 2025 PMID: 40232770, DOI: 10.1037/tra0001888.
- Crusto C, Kaufman J, Harvanek Z, Nelson C, Forray A. Perceptions of Care and Perceived Discrimination: A Qualitative Assessment of Adults Living with Sickle Cell Disease. Journal Of Racial And Ethnic Health Disparities 2024, 1-10. PMID: 39227547, DOI: 10.1007/s40615-024-02153-3.
- Harvanek Z, Kudinova A, Wong S, Xu K, Brick L, Daniels T, Marsit C, Burt A, Sinha R, Tyrka A. Childhood adversity, accelerated GrimAge, and associated health consequences. Journal Of Behavioral Medicine 2024, 47: 913-926. PMID: 38762606, PMCID: PMC11365810, DOI: 10.1007/s10865-024-00496-0.
- Holloway T, Harvanek Z, Xu K, Gordon D, Sinha R. Greater Stress and Trauma Mediate Race-Related Differences in Epigenetic Age Between Black and White Young Adults in a Community Sample. Biological Psychiatry 2024, 95: s41. DOI: 10.1016/j.biopsych.2024.02.104.
- Harvanek Z, Zhang X, Xu K, Sinha R. 353. Methylation of CRHR1 and CRHR2 is Associated With Lifetime Adversity, HPA-Axis Signaling Changes, and Obesity. Biological Psychiatry 2024, 95: s244. DOI: 10.1016/j.biopsych.2024.02.852.
- Holloway T, Harvanek Z, Xu K, Gordon D, Sinha R. Greater stress and trauma mediate race-related differences in epigenetic age between Black and White young adults in a community sample. Neurobiology Of Stress 2023, 26: 100557. PMID: 37501940, PMCID: PMC10369475, DOI: 10.1016/j.ynstr.2023.100557.
- Harvanek Z, Boks M, Vinkers C, Higgins-Chen A. The Cutting Edge of Epigenetic Clocks: In Search of Mechanisms Linking Aging and Mental Health. Biological Psychiatry 2023, 94: 694-705. PMID: 36764569, PMCID: PMC10409884, DOI: 10.1016/j.biopsych.2023.02.001.
- Holloway T, Harvanek Z, Xu K, Gordon D, Sinha R. P75. Stress and Trauma Mediate Some, But Not All, Differences in GrimAge Acceleration Between Black and White Participants in Observed Cohort Study. Biological Psychiatry 2022, 91: s117. DOI: 10.1016/j.biopsych.2022.02.309.
- Harvanek ZM, Fogelman N, Xu K, Sinha R. Psychological and biological resilience modulates the effects of stress on epigenetic aging. Translational Psychiatry 2021, 11: 601. PMID: 34839356, PMCID: PMC8627511, DOI: 10.1038/s41398-021-01735-7.
- Gendron CM, Chakraborty TS, Chung BY, Harvanek ZM, Holme KJ, Johnson JC, Lyu Y, Munneke AS, Pletcher SD. Neuronal Mechanisms that Drive Organismal Aging Through the Lens of Perception. Annual Review Of Physiology 2019, 82: 1-23. PMID: 31635526, PMCID: PMC7012701, DOI: 10.1146/annurev-physiol-021119-034440.
- Harvanek ZM, Millard H. A Structured Approach to Introducing Residents to Group Therapy Leadership. Academic Psychiatry 2019, 43: 652-653. PMID: 31485999, DOI: 10.1007/s40596-019-01112-z.
- Henderson D, Huebner C, Markowitz M, Taube N, Harvanek ZM, Jakob U, Knoefler D. Do developmental temperatures affect redox level and lifespan in C. elegans through upregulation of peroxiredoxin? Redox Biology 2017, 14: 386-390. PMID: 29055282, PMCID: PMC5647470, DOI: 10.1016/j.redox.2017.10.003.
- Harvanek ZM, Lyu Y, Gendron CM, Johnson JC, Kondo S, Promislow DEL, Pletcher SD. Perceptive costs of reproduction drive ageing and physiology in male Drosophila. Nature Ecology & Evolution 2017, 1: 0152. PMID: 28812624, PMCID: PMC5657004, DOI: 10.1038/s41559-017-0152.
- Harvanek ZM, Mourão MA, Schnell S, Pletcher SD. A computational approach to studying ageing at the individual level. Proceedings Of The Royal Society B 2016, 283: 20152346. PMID: 26865300, PMCID: PMC4760160, DOI: 10.1098/rspb.2015.2346.
- Ro J, Harvanek ZM, Pletcher SD. FLIC: High-Throughput, Continuous Analysis of Feeding Behaviors in Drosophila. PLOS ONE 2014, 9: e101107. PMID: 24978054, PMCID: PMC4076220, DOI: 10.1371/journal.pone.0101107.
- Waterson MJ, Chung BY, Harvanek ZM, Ostojic I, Alcedo J, Pletcher SD. Water sensor ppk28 modulates Drosophila lifespan and physiology through AKH signaling. Proceedings Of The National Academy Of Sciences Of The United States Of America 2014, 111: 8137-8142. PMID: 24821805, PMCID: PMC4050545, DOI: 10.1073/pnas.1315461111.
- Gendron CM, Kuo TH, Harvanek ZM, Chung BY, Yew JY, Dierick HA, Pletcher SD. Drosophila Life Span and Physiology Are Modulated by Sexual Perception and Reward. Science 2013, 343: 544-548. PMID: 24292624, PMCID: PMC4042187, DOI: 10.1126/science.1243339.
- Tang W, Dominska M, Greenwell PW, Harvanek Z, Lobachev KS, Kim HM, Narayanan V, Mirkin SM, Petes TD. Friedreich's Ataxia (GAA)n•(TTC)n Repeats Strongly Stimulate Mitotic Crossovers in Saccharomyces cerevisae. PLOS Genetics 2011, 7: e1001270. PMID: 21249181, PMCID: PMC3020933, DOI: 10.1371/journal.pgen.1001270.