Lei Chen, MD, MHS, BS
Pediatrics, Pediatric Emergency Medicine
Biography
Lei Chen, MD, MHS, specializes in pediatric emergency medicine and treats children in the hospital suffering from trauma, seizures, asthma, abdominal pain and other conditions.
Dr. Chen is interested in adapting existing technologies to better care for children in developing countries. Calling the 2003 book, Mountains Beyond Mountains: The Quest of Dr. Paul Farmer, A Man Who Would Cure the World an inspiration, Dr. Chen is focused on “global health efforts to improve emergency and critical care of children in resource-limited settings.” He says, “I am currently mentoring a group of students to build a low-cost respirator for the developing world.”
Dr. Chen is an associate professor of pediatrics (emergency medicine) and of emergency medicine at Yale School of Medicine.
Titles
- Professor of Pediatrics (Emergency Medicine) and of Emergency Medicine
- Affiliated Faculty, Yale Institute for Global Health
- Associate Professor of Emergency Medicine
Education & Training
- MHSYale University School of Medicine (2010)
- FellowYale-New Haven Children's Hospital (2004)
- FellowYale-New Haven Children's Hospital (2001)
- ResidentYale-New Haven Children's Hospital (2000)
- MDNew York University School of Medicine (1997)
- MDNew York University - School of Medicine (1995)
- BSCalifornia Institute of Technology (1992)
- ResidencyYale New Haven Hospital, New Haven, CT
Languages Spoken
- 官話 / 官话 (Chinese-Mandarin)
- English
Additional Information
Board Certifications
- AB of Pediatrics, Pediatric Emergency Medicine (2006, recertified: 2015)
- AB of Pediatrics, Pediatrics (2000, recertified: 2007)
Publications
- Qi Q, Zhang H, Jin Z, Wang C, Xia M, Chen B, Lv B, Peres Diaz L, Li X, Feng R, Qiu M, Li Y, Meseguer D, Zheng X, Wang W, Song W, Huang H, Wu H, Chen L, Schneeberger M, Yu X. Hydrogen sulfide produced by the gut microbiota impairs host metabolism via reducing GLP-1 levels in male mice. Nature Metabolism 2024, 6: 1601-1615. PMID: 39030389, DOI: 10.1038/s42255-024-01068-x.
- Umuhoza C, Chen L, Unyuzumutima J, McCall N. Impact of structured basic life-support course on nurses' cardiopulmonary resuscitation knowledge and skills: Experience of a paediatric department in low-resource country. African Journal Of Emergency Medicine 2021, 11: 366-371. PMID: 34367898, PMCID: PMC8327485, DOI: 10.1016/j.afjem.2021.03.014.
- Soma G, Chen L. High Hopes for Very Preterm Infants in Neonatal Intensive Care Units in China. JAMA Network Open 2021, 4: e2113649. PMID: 34137833, DOI: 10.1001/jamanetworkopen.2021.13649.
- Riera A, Weeks B, Emerson BL, Chen L. Evaluation of a Focused Cardiac Ultrasound Protocol in a Pediatric Emergency Department. Pediatric Emergency Care 2021, 37: 191-198. PMID: 29746359, DOI: 10.1097/PEC.0000000000001495.
- Riera A, Leviter JI, Iqbal A, Soma G, Malik RN, Chen L. Agreement With Pediatric Suprapatellar Bursa Effusion Assessments by Point-of-Care Ultrasound After Remote Training. Pediatric Emergency Care 2021, 38: e746-e751. PMID: 34542989, DOI: 10.1097/pec.0000000000002341.
- Hossain R, Qadri U, Dembowski N, Garcia A, Chen L, Cicero MX, Riera A. Sound and Air. Pediatric Emergency Care 2020, 37: e1544-e1548. PMID: 32925707, DOI: 10.1097/pec.0000000000002112.
- Bangura JB, Xiao S, Qiu D, Ouyang F, Chen L. Barriers to childhood immunization in sub-Saharan Africa: A systematic review. BMC Public Health 2020, 20: 1108. PMID: 32664849, PMCID: PMC7362649, DOI: 10.1186/s12889-020-09169-4.
- Whitney RE, Riera A, Chen L. Accuracy of Remote Interpretation of Pediatric Emergency Ultrasound Over Third Generation Networks Across Continents. Pediatric Emergency Care 2020, 36: e340-e342. PMID: 31851076, DOI: 10.1097/PEC.0000000000001948.
- Smith AL, Chen L. Incidence and Imminence of Pregnancy in At-Risk Teens After Emergency Department Visits. Pediatric Emergency Care 2019, 35: 837-839. PMID: 31790072, DOI: 10.1097/PEC.0000000000001989.
- Riera A, Hayward H, Silva C, Chen L. Reevaluation of FAST Sensitivity in Pediatric Blunt Abdominal Trauma Patients. Pediatric Emergency Care 2019, 37: e1012-e1019. PMID: 31356479, DOI: 10.1097/pec.0000000000001877.
- Ho K, Wang X, Chen L. Reasons for parental withdrawal of care in a pediatric intensive care unit in China. PLOS ONE 2018, 13: e0199419. PMID: 30044777, PMCID: PMC6059386, DOI: 10.1371/journal.pone.0199419.
- Huang R, Ning H, Baum CR, Chen L, Hsiao A. “What do you know?”——knowledge among village doctors of lead poisoning in children in rural China. BMC Public Health 2017, 17: 895. PMID: 29169343, PMCID: PMC5701361, DOI: 10.1186/s12889-017-4895-2.
- Whitney RE, Santucci K, Hsiao A, Chen L. Cost-effectiveness of point-of-care testing for dehydration in the pediatric ED. The American Journal Of Emergency Medicine 2016, 34: 1573-1575. PMID: 27289438, DOI: 10.1016/j.ajem.2016.05.075.
- Siew L, Hsiao A, McCarthy P, Agarwal A, Lee E, Chen L. Reliability of Telemedicine in the Assessment of Seriously Ill Children. Pediatrics 2016, 137: e20150712. PMID: 26908666, DOI: 10.1542/peds.2015-0712.
- Vieira RL, Hsu D, Nagler J, Chen L, Gallagher R, Levy JA. Pediatric emergency medicine fellow training in ultrasound: consensus educational guidelines. Academic Emergency Medicine : Official Journal Of The Society For Academic Emergency Medicine 2013, 20: 300-6. PMID: 23517263, DOI: 10.1111/acem.12087.
- Faustino EV, Spinella PC, Li S, Pinto MG, Stoltz P, Tala J, Card ME, Northrup V, Baker KE, Goodman TR, Chen L, Silva CT. Incidence and Acute Complications of Asymptomatic Central Venous Catheter–Related Deep Venous Thrombosis in Critically Ill Children. The Journal Of Pediatrics 2012, 162: 387-391. PMID: 22883418, PMCID: PMC3575007, DOI: 10.1016/j.jpeds.2012.06.059.
- Riera A, Chen L. Ultrasound Evaluation of Skull Fractures in Children. Pediatric Emergency Care 2012, 28: 420-425. PMID: 22531195, DOI: 10.1097/pec.0b013e318252da3b.
- Riera A, Hsiao AL, Langhan ML, Goodman TR, Chen L. Diagnosis of Intussusception by Physician Novice Sonographers in the Emergency Department. Annals Of Emergency Medicine 2012, 60: 264-268. PMID: 22424652, PMCID: PMC3431911, DOI: 10.1016/j.annemergmed.2012.02.007.
- Chen L, Hsiao A, Langhan M, Riera A, Santucci KA. Use of Bedside Ultrasound to Assess Degree of Dehydration in Children With Gastroenteritis. Academic Emergency Medicine 2010, 17: 1042-1047. PMID: 21040104, PMCID: PMC3058669, DOI: 10.1111/j.1553-2712.2010.00873.x.
- Yoo A, Staahl B, Chen L, Crabtree G. Erratum: MicroRNA-mediated switching of chromatin-remodelling complexes in neural development. Nature 2009, 461: 296-296. DOI: 10.1038/nature08359.
- Chen L, Hsiao AL. Randomized Trial of Endotracheal Tube Versus Laryngeal Mask Airway in Simulated Prehospital Pediatric Arrest. 2008, 122: e294-e297. PMID: 18644845, DOI: 10.1542/peds.2008-0103.
- Langhan ML, Chen L. Current Utilization of Continuous End-Tidal Carbon Dioxide Monitoring in Pediatric Emergency Departments. Pediatric Emergency Care 2008, 24: 211-213. PMID: 18431217, DOI: 10.1097/pec.0b013e31816a8d31.
- Chen L, Kim Y, Santucci KA. Use of Ultrasound Measurement of the Inferior Vena Cava Diameter as an Objective Tool in the Assessment of Children with Clinical Dehydration. Academic Emergency Medicine 2007, 14: 841-845. PMID: 17898246, DOI: 10.1197/j.aem.2007.06.040.
- Chen L, Kim Y, Santucci K. Use of Ultrasound Measurement of the Inferior Vena Cava Diameter as an Objective Tool in the Assessment of Children with Clinical Dehydration. Academic Emergency Medicine 2007, 14: 841-845. DOI: 10.1111/j.1553-2712.2007.tb02314.x.
- Chen L, Kim Y, Moore CL. Diagnosis and Guided Reduction of Forearm Fractures in Children Using Bedside Ultrasound. Pediatric Emergency Care 2007, 23: 528-531. PMID: 17726410, DOI: 10.1097/pec.0b013e318128f85d.
- Chen L, Santucci K. PROBING THE AVAILABILITY OF EMERGENCY ULTRASOUND IN PEDIATRICS. Pediatric Emergency Care 2006, 22: 688. DOI: 10.1097/00006565-200609000-00041.
- Hsiao AL, Chen L, Baker MD. Incidence and Predictors of Serious Bacterial Infections Among 57- to 180-Day-Old Infants. 2006, 117: 1695-1701. PMID: 16651326, DOI: 10.1542/peds.2005-1673.
- Chen L, Hsiao AL, Moore CL, Dziura JD, Santucci KA. Utility of Bedside Bladder Ultrasound Before Urethral Catheterization in Young Children. 2005, 115: 108-111. PMID: 15629989, DOI: 10.1542/peds.2004-0738.
- Bao S, Chen L, Kim J, Thompson R. Cerebellar cortical inhibition and classical eyeblink conditioning. Proceedings Of The National Academy Of Sciences Of The United States Of America 2002, 99: 1592-1597. PMID: 11805298, PMCID: PMC122235, DOI: 10.1073/pnas.032655399.
- Bao S, Chen L, Thompson R. Learning- and Cerebellum-Dependent Neuronal Activity in the Lateral Pontine Nucleus. Behavioral Neuroscience 2000, 114: 254-261. PMID: 10832787, DOI: 10.1037/0735-7044.114.2.254.
- Chen L, Bao S, Qiao X, Thompson R. Impaired cerebellar synapse maturation in waggler, a mutant mouse with a disrupted neuronal calcium channel γ subunit. Proceedings Of The National Academy Of Sciences Of The United States Of America 1999, 96: 12132-12137. PMID: 10518588, PMCID: PMC18424, DOI: 10.1073/pnas.96.21.12132.
- Bao S, Chen L, Qiao X, Thompson R. Transgenic Brain-Derived Neurotrophic Factor Modulates a Developing Cerebellar Inhibitory Synapse. Learning & Memory 1999, 6: 276-283. PMID: 10492009, PMCID: PMC311309, DOI: 10.1101/lm.6.3.276.
- Chen L, Bao S, Thompson R. Bilateral Lesions of the Interpositus Nucleus Completely Prevent Eyeblink Conditioning in Purkinje Cell-Degeneration Mutant Mice. Behavioral Neuroscience 1999, 113: 204-210. PMID: 10197920, DOI: 10.1037/0735-7044.113.1.204.
- Bao S, Chen L, Qiao X, Knusel B, Thompson R. Impaired Eye-Blink Conditioning in waggler, a Mutant Mouse With Cerebellar BDNF Deficiency. Learning & Memory 1998, 5: 355-364. PMID: 10454360, PMCID: PMC311271, DOI: 10.1101/lm.5.4.355.
- Qiao X, Chen L, Gao H, Bao S, Hefti F, Thompson R, Knusel B. Cerebellar Brain-Derived Neurotrophic Factor–TrkB Defect Associated with Impairment of Eyeblink Conditioning in StargazerMutant Mice. Journal Of Neuroscience 1998, 18: 6990-6999. PMID: 9712667, PMCID: PMC6792950, DOI: 10.1523/jneurosci.18-17-06990.1998.
- Bao S, Chen L, Thompson R. Classical Eyeblink Conditioning in Two Strains of Mice: Conditioned Responses, Sensitization, and Spontaneous Eyeblinks. Behavioral Neuroscience 1998, 112: 714-718. PMID: 9676986, DOI: 10.1037/0735-7044.112.3.714.
- Kim J, Shih J, Chen K, Chen L, Bao S, Maren S, Anagnostaras S, Fanselow M, De Maeyer E, Seif I, Thompson R. Selective enhancement of emotional, but not motor, learning in monoamine oxidase A-deficient mice. Proceedings Of The National Academy Of Sciences Of The United States Of America 1997, 94: 5929-5933. PMID: 9159177, PMCID: PMC20883, DOI: 10.1073/pnas.94.11.5929.
- Thompson R, Bao S, Chen L, Cipriano B, Grethe J, Kim J, Thompson J, Tracy J, Weninger M, Krupa D. Associative Learning. International Review Of Neurobiology 1997, 41: 151-189. PMID: 9378587, DOI: 10.1016/s0074-7742(08)60351-7.
- Shibuki K, Gomi H, Chen L, Bao S, Kim J, Wakatsuki H, Fujisaki T, Fujimoto K, Katoh A, Ikeda T, Chen C, Thompson R, Itohara S. Deficient Cerebellar Long-Term Depression, Impaired Eyeblink Conditioning, and Normal Motor Coordination in GFAP Mutant Mice. Neuron 1996, 16: 587-599. PMID: 8785056, DOI: 10.1016/s0896-6273(00)80078-1.
- Chen C, Kano M, Abeliovich A, Chen L, Bao S, Kim J, Hashimoto K, Thompson R, Tonegawa S. Impaired motor coordination correlates with persistent multiple climbing fiber innervation in PKCγ mutant mice. Cell 1995, 83: 1233-1242. PMID: 8548809, DOI: 10.1016/0092-8674(95)90148-5.
Departments and Programs
Biography
Lei Chen, MD, MHS, specializes in pediatric emergency medicine and treats children in the hospital suffering from trauma, seizures, asthma, abdominal pain and other conditions.
Dr. Chen is interested in adapting existing technologies to better care for children in developing countries. Calling the 2003 book, Mountains Beyond Mountains: The Quest of Dr. Paul Farmer, A Man Who Would Cure the World an inspiration, Dr. Chen is focused on “global health efforts to improve emergency and critical care of children in resource-limited settings.” He says, “I am currently mentoring a group of students to build a low-cost respirator for the developing world.”
Dr. Chen is an associate professor of pediatrics (emergency medicine) and of emergency medicine at Yale School of Medicine.
Titles
- Professor of Pediatrics (Emergency Medicine) and of Emergency Medicine
- Affiliated Faculty, Yale Institute for Global Health
- Associate Professor of Emergency Medicine
Education & Training
- MHSYale University School of Medicine (2010)
- FellowYale-New Haven Children's Hospital (2004)
- FellowYale-New Haven Children's Hospital (2001)
- ResidentYale-New Haven Children's Hospital (2000)
- MDNew York University School of Medicine (1997)
- MDNew York University - School of Medicine (1995)
- BSCalifornia Institute of Technology (1992)
- ResidencyYale New Haven Hospital, New Haven, CT
Languages Spoken
- 官話 / 官话 (Chinese-Mandarin)
- English
Additional Information
Board Certifications
- AB of Pediatrics, Pediatric Emergency Medicine (2006, recertified: 2015)
- AB of Pediatrics, Pediatrics (2000, recertified: 2007)
Publications
- Qi Q, Zhang H, Jin Z, Wang C, Xia M, Chen B, Lv B, Peres Diaz L, Li X, Feng R, Qiu M, Li Y, Meseguer D, Zheng X, Wang W, Song W, Huang H, Wu H, Chen L, Schneeberger M, Yu X. Hydrogen sulfide produced by the gut microbiota impairs host metabolism via reducing GLP-1 levels in male mice. Nature Metabolism 2024, 6: 1601-1615. PMID: 39030389, DOI: 10.1038/s42255-024-01068-x.
- Umuhoza C, Chen L, Unyuzumutima J, McCall N. Impact of structured basic life-support course on nurses' cardiopulmonary resuscitation knowledge and skills: Experience of a paediatric department in low-resource country. African Journal Of Emergency Medicine 2021, 11: 366-371. PMID: 34367898, PMCID: PMC8327485, DOI: 10.1016/j.afjem.2021.03.014.
- Soma G, Chen L. High Hopes for Very Preterm Infants in Neonatal Intensive Care Units in China. JAMA Network Open 2021, 4: e2113649. PMID: 34137833, DOI: 10.1001/jamanetworkopen.2021.13649.
- Riera A, Weeks B, Emerson BL, Chen L. Evaluation of a Focused Cardiac Ultrasound Protocol in a Pediatric Emergency Department. Pediatric Emergency Care 2021, 37: 191-198. PMID: 29746359, DOI: 10.1097/PEC.0000000000001495.
- Riera A, Leviter JI, Iqbal A, Soma G, Malik RN, Chen L. Agreement With Pediatric Suprapatellar Bursa Effusion Assessments by Point-of-Care Ultrasound After Remote Training. Pediatric Emergency Care 2021, 38: e746-e751. PMID: 34542989, DOI: 10.1097/pec.0000000000002341.
- Hossain R, Qadri U, Dembowski N, Garcia A, Chen L, Cicero MX, Riera A. Sound and Air. Pediatric Emergency Care 2020, 37: e1544-e1548. PMID: 32925707, DOI: 10.1097/pec.0000000000002112.
- Bangura JB, Xiao S, Qiu D, Ouyang F, Chen L. Barriers to childhood immunization in sub-Saharan Africa: A systematic review. BMC Public Health 2020, 20: 1108. PMID: 32664849, PMCID: PMC7362649, DOI: 10.1186/s12889-020-09169-4.
- Whitney RE, Riera A, Chen L. Accuracy of Remote Interpretation of Pediatric Emergency Ultrasound Over Third Generation Networks Across Continents. Pediatric Emergency Care 2020, 36: e340-e342. PMID: 31851076, DOI: 10.1097/PEC.0000000000001948.
- Smith AL, Chen L. Incidence and Imminence of Pregnancy in At-Risk Teens After Emergency Department Visits. Pediatric Emergency Care 2019, 35: 837-839. PMID: 31790072, DOI: 10.1097/PEC.0000000000001989.
- Riera A, Hayward H, Silva C, Chen L. Reevaluation of FAST Sensitivity in Pediatric Blunt Abdominal Trauma Patients. Pediatric Emergency Care 2019, 37: e1012-e1019. PMID: 31356479, DOI: 10.1097/pec.0000000000001877.
- Ho K, Wang X, Chen L. Reasons for parental withdrawal of care in a pediatric intensive care unit in China. PLOS ONE 2018, 13: e0199419. PMID: 30044777, PMCID: PMC6059386, DOI: 10.1371/journal.pone.0199419.
- Huang R, Ning H, Baum CR, Chen L, Hsiao A. “What do you know?”——knowledge among village doctors of lead poisoning in children in rural China. BMC Public Health 2017, 17: 895. PMID: 29169343, PMCID: PMC5701361, DOI: 10.1186/s12889-017-4895-2.
- Whitney RE, Santucci K, Hsiao A, Chen L. Cost-effectiveness of point-of-care testing for dehydration in the pediatric ED. The American Journal Of Emergency Medicine 2016, 34: 1573-1575. PMID: 27289438, DOI: 10.1016/j.ajem.2016.05.075.
- Siew L, Hsiao A, McCarthy P, Agarwal A, Lee E, Chen L. Reliability of Telemedicine in the Assessment of Seriously Ill Children. Pediatrics 2016, 137: e20150712. PMID: 26908666, DOI: 10.1542/peds.2015-0712.
- Vieira RL, Hsu D, Nagler J, Chen L, Gallagher R, Levy JA. Pediatric emergency medicine fellow training in ultrasound: consensus educational guidelines. Academic Emergency Medicine : Official Journal Of The Society For Academic Emergency Medicine 2013, 20: 300-6. PMID: 23517263, DOI: 10.1111/acem.12087.
- Faustino EV, Spinella PC, Li S, Pinto MG, Stoltz P, Tala J, Card ME, Northrup V, Baker KE, Goodman TR, Chen L, Silva CT. Incidence and Acute Complications of Asymptomatic Central Venous Catheter–Related Deep Venous Thrombosis in Critically Ill Children. The Journal Of Pediatrics 2012, 162: 387-391. PMID: 22883418, PMCID: PMC3575007, DOI: 10.1016/j.jpeds.2012.06.059.
- Riera A, Chen L. Ultrasound Evaluation of Skull Fractures in Children. Pediatric Emergency Care 2012, 28: 420-425. PMID: 22531195, DOI: 10.1097/pec.0b013e318252da3b.
- Riera A, Hsiao AL, Langhan ML, Goodman TR, Chen L. Diagnosis of Intussusception by Physician Novice Sonographers in the Emergency Department. Annals Of Emergency Medicine 2012, 60: 264-268. PMID: 22424652, PMCID: PMC3431911, DOI: 10.1016/j.annemergmed.2012.02.007.
- Chen L, Hsiao A, Langhan M, Riera A, Santucci KA. Use of Bedside Ultrasound to Assess Degree of Dehydration in Children With Gastroenteritis. Academic Emergency Medicine 2010, 17: 1042-1047. PMID: 21040104, PMCID: PMC3058669, DOI: 10.1111/j.1553-2712.2010.00873.x.
- Yoo A, Staahl B, Chen L, Crabtree G. Erratum: MicroRNA-mediated switching of chromatin-remodelling complexes in neural development. Nature 2009, 461: 296-296. DOI: 10.1038/nature08359.
- Chen L, Hsiao AL. Randomized Trial of Endotracheal Tube Versus Laryngeal Mask Airway in Simulated Prehospital Pediatric Arrest. 2008, 122: e294-e297. PMID: 18644845, DOI: 10.1542/peds.2008-0103.
- Langhan ML, Chen L. Current Utilization of Continuous End-Tidal Carbon Dioxide Monitoring in Pediatric Emergency Departments. Pediatric Emergency Care 2008, 24: 211-213. PMID: 18431217, DOI: 10.1097/pec.0b013e31816a8d31.
- Chen L, Kim Y, Santucci KA. Use of Ultrasound Measurement of the Inferior Vena Cava Diameter as an Objective Tool in the Assessment of Children with Clinical Dehydration. Academic Emergency Medicine 2007, 14: 841-845. PMID: 17898246, DOI: 10.1197/j.aem.2007.06.040.
- Chen L, Kim Y, Santucci K. Use of Ultrasound Measurement of the Inferior Vena Cava Diameter as an Objective Tool in the Assessment of Children with Clinical Dehydration. Academic Emergency Medicine 2007, 14: 841-845. DOI: 10.1111/j.1553-2712.2007.tb02314.x.
- Chen L, Kim Y, Moore CL. Diagnosis and Guided Reduction of Forearm Fractures in Children Using Bedside Ultrasound. Pediatric Emergency Care 2007, 23: 528-531. PMID: 17726410, DOI: 10.1097/pec.0b013e318128f85d.
- Chen L, Santucci K. PROBING THE AVAILABILITY OF EMERGENCY ULTRASOUND IN PEDIATRICS. Pediatric Emergency Care 2006, 22: 688. DOI: 10.1097/00006565-200609000-00041.
- Hsiao AL, Chen L, Baker MD. Incidence and Predictors of Serious Bacterial Infections Among 57- to 180-Day-Old Infants. 2006, 117: 1695-1701. PMID: 16651326, DOI: 10.1542/peds.2005-1673.
- Chen L, Hsiao AL, Moore CL, Dziura JD, Santucci KA. Utility of Bedside Bladder Ultrasound Before Urethral Catheterization in Young Children. 2005, 115: 108-111. PMID: 15629989, DOI: 10.1542/peds.2004-0738.
- Bao S, Chen L, Kim J, Thompson R. Cerebellar cortical inhibition and classical eyeblink conditioning. Proceedings Of The National Academy Of Sciences Of The United States Of America 2002, 99: 1592-1597. PMID: 11805298, PMCID: PMC122235, DOI: 10.1073/pnas.032655399.
- Bao S, Chen L, Thompson R. Learning- and Cerebellum-Dependent Neuronal Activity in the Lateral Pontine Nucleus. Behavioral Neuroscience 2000, 114: 254-261. PMID: 10832787, DOI: 10.1037/0735-7044.114.2.254.
- Chen L, Bao S, Qiao X, Thompson R. Impaired cerebellar synapse maturation in waggler, a mutant mouse with a disrupted neuronal calcium channel γ subunit. Proceedings Of The National Academy Of Sciences Of The United States Of America 1999, 96: 12132-12137. PMID: 10518588, PMCID: PMC18424, DOI: 10.1073/pnas.96.21.12132.
- Bao S, Chen L, Qiao X, Thompson R. Transgenic Brain-Derived Neurotrophic Factor Modulates a Developing Cerebellar Inhibitory Synapse. Learning & Memory 1999, 6: 276-283. PMID: 10492009, PMCID: PMC311309, DOI: 10.1101/lm.6.3.276.
- Chen L, Bao S, Thompson R. Bilateral Lesions of the Interpositus Nucleus Completely Prevent Eyeblink Conditioning in Purkinje Cell-Degeneration Mutant Mice. Behavioral Neuroscience 1999, 113: 204-210. PMID: 10197920, DOI: 10.1037/0735-7044.113.1.204.
- Bao S, Chen L, Qiao X, Knusel B, Thompson R. Impaired Eye-Blink Conditioning in waggler, a Mutant Mouse With Cerebellar BDNF Deficiency. Learning & Memory 1998, 5: 355-364. PMID: 10454360, PMCID: PMC311271, DOI: 10.1101/lm.5.4.355.
- Qiao X, Chen L, Gao H, Bao S, Hefti F, Thompson R, Knusel B. Cerebellar Brain-Derived Neurotrophic Factor–TrkB Defect Associated with Impairment of Eyeblink Conditioning in StargazerMutant Mice. Journal Of Neuroscience 1998, 18: 6990-6999. PMID: 9712667, PMCID: PMC6792950, DOI: 10.1523/jneurosci.18-17-06990.1998.
- Bao S, Chen L, Thompson R. Classical Eyeblink Conditioning in Two Strains of Mice: Conditioned Responses, Sensitization, and Spontaneous Eyeblinks. Behavioral Neuroscience 1998, 112: 714-718. PMID: 9676986, DOI: 10.1037/0735-7044.112.3.714.
- Kim J, Shih J, Chen K, Chen L, Bao S, Maren S, Anagnostaras S, Fanselow M, De Maeyer E, Seif I, Thompson R. Selective enhancement of emotional, but not motor, learning in monoamine oxidase A-deficient mice. Proceedings Of The National Academy Of Sciences Of The United States Of America 1997, 94: 5929-5933. PMID: 9159177, PMCID: PMC20883, DOI: 10.1073/pnas.94.11.5929.
- Thompson R, Bao S, Chen L, Cipriano B, Grethe J, Kim J, Thompson J, Tracy J, Weninger M, Krupa D. Associative Learning. International Review Of Neurobiology 1997, 41: 151-189. PMID: 9378587, DOI: 10.1016/s0074-7742(08)60351-7.
- Shibuki K, Gomi H, Chen L, Bao S, Kim J, Wakatsuki H, Fujisaki T, Fujimoto K, Katoh A, Ikeda T, Chen C, Thompson R, Itohara S. Deficient Cerebellar Long-Term Depression, Impaired Eyeblink Conditioning, and Normal Motor Coordination in GFAP Mutant Mice. Neuron 1996, 16: 587-599. PMID: 8785056, DOI: 10.1016/s0896-6273(00)80078-1.
- Chen C, Kano M, Abeliovich A, Chen L, Bao S, Kim J, Hashimoto K, Thompson R, Tonegawa S. Impaired motor coordination correlates with persistent multiple climbing fiber innervation in PKCγ mutant mice. Cell 1995, 83: 1233-1242. PMID: 8548809, DOI: 10.1016/0092-8674(95)90148-5.
Departments and Programs