Joanna Gibson, MD, PhD
Biography
Joanna A. Gibson, MD, PhD, a pathologist, still remembers details from a lecture she heard as a graduate teaching assistant in the Mayo Clinic’s MD-PhD program in Rochester, Minn. “I remember the lecturer explained how cancer cells behaved in the body, and then showed an image of those cancer cells within a biopsy sample projected on a slide—and it just clicked for me,” Dr. Gibson says. “I loved how pathology brought the science and the patient care aspects together.” Today, Dr. Gibson specializes in diagnosing gastrointestinal and liver diseases, including cancers, at Yale Medicine.
“For each patient case, I read through the medical history and notes to get a good idea in my mind about who the patient is,” Dr. Gibson says. Even when dealing with a high volume of biopsies, taking these extra moments to put together a patient’s story is crucial, she says.
As an assistant professor of pathology at Yale School of Medicine, Dr. Gibson also conducts research on the pathology of gastrointestinal diseases.
Titles
- Associate Professor of Pathology
- Director of Quality and Patient Safety, Pathology
Education & Training
- FellowshipBrigham & Women's Hospital (2009)
- ResidencyBrigham & Women's Hospital (2008)
- PhDMayo Clinic College of Medicine (2004)
- MDMayo Clinic College of Medicine (2004)
Languages Spoken
- English
Additional Information
- Aladelokun O, Lu L, Zheng J, Yan H, Jain A, Gibson J, Khan S, Johnson C. Growth characteristics of HCT116 xenografts lacking asparagine synthetase vary according to sex. Human Genomics 2024, 18: 67. PMID: 38886847, PMCID: PMC11184737, DOI: 10.1186/s40246-024-00635-3.
- Singh V, Mezzacappa C, Gershkovich P, Di Giovanna J, Ganzak A, Gibson J, Sinard J, Xicola RM, Llor X. Systems approach to enhance Lynch syndrome diagnosis through tumour testing. Journal Of Medical Genetics 2022, 60: 533-539. PMID: 36115663, PMCID: PMC10020126, DOI: 10.1136/jmg-2022-108770.
- Giner-Calabuig M, De Leon S, Vidal-Pedrola G, Fehlmann T, Ukaegbu C, Gibson J, Picó M, Alenda C, Reyes J, Ortega S, LLado C, de la Torre Rubio P, Obrador-Hevia A, Castillejo A, Soto J, Castellví-Bel S, Syngal S, Stoffel E, Ellis N, Jover R, Llor X, Xicola R. Tu1100: HETEROZYGOUS MUTATIONS IN DNA REPAIR GENES CONFER GENETIC SUSCEPTIILITY TO COLORECTAL CANCER AMONG LYNCH-LIKE CASES. Gastroenterology 2022, 162: s-883. DOI: 10.1016/s0016-5085(22)62088-2.
- Matsumoto N, Barbieri A, Gershkovich P, Cecchini M, Gibson J. QIM22-192: Mismatch Repair Protein Immunohistochemistry: Quality of Mismatch Repair Deficiency Detection. Journal Of The National Comprehensive Cancer Network 2022, 20: qim22-192. DOI: 10.6004/jnccn.2021.7192.
- Giner-Calabuig M, De Leon S, Wang J, Fehlmann TD, Ukaegbu C, Gibson J, Alustiza-Fernandez M, Pico MD, Alenda C, Herraiz M, Carrillo-Palau M, Salces I, Reyes J, Ortega SP, Obrador-Hevia A, Cecchini M, Syngal S, Stoffel E, Ellis NA, Sweasy J, Jover R, Llor X, Xicola RM. Mutational signature profiling classifies subtypes of clinically different mismatch-repair-deficient tumours with a differential immunogenic response potential. British Journal Of Cancer 2022, 126: 1595-1603. PMID: 35197584, PMCID: PMC9130322, DOI: 10.1038/s41416-022-01754-1.
- Li H, Zhang X, Finberg KE, Walther Z, Jain D, Gibson J. Pathogenic BRCA2 germline variants in combined hepatocellular‐cholangiocarcinoma. Pathology International 2021, 72: 138-140. PMID: 34808016, DOI: 10.1111/pin.13188.
- Gibson JA, Finberg KE, Nalbantoglu I, Cecchini M, Ganzak A, Walther Z, Sklar JL, Eder JP, Goldberg SB. Yale Cancer Center Precision Medicine Tumor Board: molecular findings alter a diagnosis and treatment plan. The Lancet Oncology 2021, 22: 306-307. PMID: 33662283, DOI: 10.1016/s1470-2045(20)30683-5.
- Morrow JS, Gershkovich P, Gibson J, Gilshannon M, Kowalski D, Levi AW, Nguyen DX, Rimm DL, Xu ML, Sinard J. Measuring Faculty Effort: A Quantitative Approach That Aligns Personal and Institutional Goals in Pathology at Yale. Academic Pathology 2021, 8: 23742895211047985. PMID: 34646939, PMCID: PMC8504692, DOI: 10.1177/23742895211047985.
- Singh V, Ganzak A, Gershkovich P, Gibson J, Llor X. 1 IMPROVING LYNCH SYNDROME IDENTIFICATION THROUGH THE IMPLEMENTATION OF ENHANCED TUMOR TESTING AND A COMPREHENSIVE SYSTEMS APPROACH. Gastroenterology 2020, 158: s-1. DOI: 10.1016/s0016-5085(20)30682-x.
- Patel N, Barbieri A, Gibson J. Neuroendocrine Tumors of the Gastrointestinal Tract and Pancreas. Surgical Pathology Clinics 2019, 12: 1021-1044. PMID: 31672292, DOI: 10.1016/j.path.2019.08.007.
- Guerra MT, Florentino RM, Franca A, Lima Filho AC, Dos Santos ML, Fonseca RC, Lemos FO, Fonseca MC, Kruglov E, Mennone A, Njei B, Gibson J, Guan F, Cheng YC, Ananthanarayanan M, Gu J, Jiang J, Zhao H, Lima CX, Vidigal PT, Oliveira AG, Nathanson MH, Leite MF. Expression of the type 3 InsP3 receptor is a final common event in the development of hepatocellular carcinoma. Gut 2019, 68: 1676. PMID: 31315892, PMCID: PMC7087395, DOI: 10.1136/gutjnl-2018-317811.
- Paulson N, Gibson J, Glusac E. Perianal and perineal keratoacanthoma: Two cases demonstrating histologic similarity to subungual keratoacanthoma. Journal Of Cutaneous Pathology 2019, 46: 794-797. PMID: 31148238, DOI: 10.1111/cup.13518.
- Celli R, Hui P, Triscott H, Bogardus S, Gibson J, Hwang M, Robert ME. Clinical Insignficance of Monoclonal T-Cell Populations and Duodenal Intraepithelial T-Cell Phenotypes in Celiac and Nonceliac Patients. The American Journal Of Surgical Pathology 2019, 43: 151-160. PMID: 30334829, DOI: 10.1097/pas.0000000000001172.
- Gibson J, Odze R. 5 Tissue Sampling, Specimen Handling, and Laboratory Processing. 2019, 51-68.e6. DOI: 10.1016/b978-0-323-41509-5.00005-0.
- Rodriguez NJ, Gupta N, Gibson J. Autoimmune Enteropathy in an Ulcerative Colitis Patient. ACG Case Reports Journal 2018, 5: e78. PMID: 30465008, PMCID: PMC6224868, DOI: 10.14309/crj.2018.78.
- Chaunzwa TL, O'Shea J, Boggs NA, Schwartz JI, Gibson J, Gielissen KA. Hemolytic Anemia and Gastric Carcinoid in a Russian Seafarer: Highlighting the Role of Diagnostic Technologies in Modern Clinical Practice. The Yale Journal Of Biology And Medicine 2018, 91: 243-246. PMID: 30258311, PMCID: PMC6153615.
- Celli R, Barbieri AL, Colunga M, Sinard J, Gibson JA. Optimal Intraoperative Assessment of Gastric Margins. American Journal Of Clinical Pathology 2018, 150: 353-363. PMID: 30020407, DOI: 10.1093/ajcp/aqy062.
- Benedict M, Gibson J, Zhang X. Epithelioid Angiosarcoma: An Unusual Cause of Gastrointestinal Bleeding. International Journal Of Surgical Pathology 2018, 27: 277-279. PMID: 29944034, DOI: 10.1177/1066896918784180.
- Gopal P, Gibson JA, Lisovsky M, Nalbantoglu I. Unique causes of esophageal inflammation: a histopathologic perspective. Annals Of The New York Academy Of Sciences 2018, 1434: 219-226. PMID: 29766506, DOI: 10.1111/nyas.13732.
- Rodriguez N, Gupta N, Gibson J. Autoimmune Enteropathy in an Ulcerative Colitis Patient. ACG Case Reports Journal 2018, 5: e781-3. DOI: 10.14309/02075970-201805110-00003.
- Rodriguez N, Gupta N, Gibson J. Autoimmune Enteropathy in an Ulcerative Colitis Patient. ACG Case Reports Journal 2018, 5: e78. DOI: 10.14309/02075970-201805000-00078.
- Cenaj O, Gibson J, Odze RD. Clinicopathologic and outcome study of sessile serrated adenomas/polyps with serrated versus intestinal dysplasia. Modern Pathology 2017, 31: 633-642. PMID: 29271414, DOI: 10.1038/modpathol.2017.169.
- Boddupalli CS, Nair S, Gray SM, Nowyhed HN, Verma R, Gibson JA, Abraham C, Narayan D, Vasquez J, Hedrick CC, Flavell RA, Dhodapkar KM, Kaech SM, Dhodapkar MV. ABC transporters and NR4A1 identify a quiescent subset of tissue-resident memory T cells. Journal Of Clinical Investigation 2016, 126: 3905-3916. PMID: 27617863, PMCID: PMC5096804, DOI: 10.1172/jci85329.
- Parikh ND, Gibson J, Nagar A, Ahmed AA, Aslanian HR. Confocal laser endomicroscopy features of sessile serrated adenomas/polyps. United European Gastroenterology Journal 2016, 4: 599-603. PMID: 27536371, PMCID: PMC4971791, DOI: 10.1177/2050640615621819.
- Gibson JA, Odze RD. Pathology of premalignant colorectal neoplasia. Digestive Endoscopy 2016, 28: 312-323. PMID: 26861656, DOI: 10.1111/den.12633.
- Parikh ND, Gibson J, Aslanian H. Gastric Fundic Gland Adenocarcinoma With Chief Cell Differentiation. Clinical Gastroenterology And Hepatology 2015, 13: a17-a18. PMID: 26215839, PMCID: PMC4829391, DOI: 10.1016/j.cgh.2015.07.023.
- Shen J, Gibson JA, Schulte S, Khurana H, Farraye FA, Levine J, Burakoff R, Cerda S, Qazi T, Hamilton M, Srivastava A, Odze RD. Clinical, pathologic, and outcome study of hyperplastic and sessile serrated polyps in inflammatory bowel disease. Human Pathology 2015, 46: 1548-1556. PMID: 26297256, DOI: 10.1016/j.humpath.2015.06.019.
- Sethi A, Jain D, Roland BC, Kinzel J, Gibson J, Schrader R, Hanson JA. Performing Colonic Mast Cell Counts in Patients With Chronic Diarrhea of Unknown Etiology Has Limited Diagnostic Use. Archives Of Pathology & Laboratory Medicine 2015, 139: 225-32. PMID: 25611105, DOI: 10.5858/arpa.2013-0594-oa.
- Rustagi T, Mansoor MS, Gibson JA, Kapadia CR. Pseudomelanosis of Stomach, Duodenum, and Jejunum. Journal Of Clinical Gastroenterology 2015, 49: 124-126. PMID: 24492404, DOI: 10.1097/mcg.0000000000000081.
- Milam A, Maher SE, Gibson JA, Lebastchi J, Wen L, Ruddle NH, Herold KC, Bothwell AL. A Humanized Mouse Model of Autoimmune Insulitis. Diabetes 2014, 63: 1712-1724. PMID: 24478396, PMCID: PMC3994947, DOI: 10.2337/db13-1141.
- Gibson J, Lacy J, Matloff E, Robert M. Microsatellite Instability Testing in Colorectal Carcinoma: A Practical Guide. Clinical Gastroenterology And Hepatology 2014, 12: 171-176.e1. PMID: 24434275, DOI: 10.1016/j.cgh.2013.11.001.
- Batts KP, Ketover S, Kakar S, Krasinskas AM, Mitchell KA, Wilcox R, Westerhoff M, Rank J, Gibson J, Mattia AR, Cummings OW, Davison JM, Naini BV, Dry SM, Yantiss RK. Appropriate Use of Special Stains for Identifying Helicobacter pylori. The American Journal Of Surgical Pathology 2013, 37: e12-e22. PMID: 24141174, DOI: 10.1097/pas.0000000000000097.
- Virk RK, Van Dyke AL, Finkelstein A, Prasad A, Gibson J, Hui P, Theoharis CG, Carling T, Roman SA, Sosa JA, Udelsman R, Prasad ML. BRAF V600E mutation in papillary thyroid microcarcinoma: a genotype–phenotype correlation. Modern Pathology 2012, 26: 62-70. PMID: 22918165, DOI: 10.1038/modpathol.2012.152.
- Gibson JA, Odze RD. Pathology of Diseases that Cause Upper Gastrointestinal Tract Bleeding. Gastrointestinal Endoscopy Clinics Of North America 2011, 21: 583-596. PMID: 21944412, DOI: 10.1016/j.giec.2011.07.006.
- Gibson JA, Hahn HP, Shahsafaei A, Odze RD. MUC Expression in Hyperplastic and Serrated Colonic Polyps. The American Journal Of Surgical Pathology 2011, 35: 742-749. PMID: 21490447, DOI: 10.1097/pas.0b013e31821537a2.
- Gibson JA, Hornick JL. Mucosal Schwann Cell “Hamartoma”. The American Journal Of Surgical Pathology 2009, 33: 781-787. PMID: 19065103, DOI: 10.1097/pas.0b013e31818dd6ca.
- Yu H, Gibson JA, Pinkus GS, Hornick JL. Podoplanin (D2-40) Is a Novel Marker for Follicular Dendritic Cell Tumors. American Journal Of Clinical Pathology 2007, 128: 776-782. PMID: 17951199, DOI: 10.1309/7p8u659jbjcv6eeu.
- Kaczynski J, Cook T, Urrutia R. Sp1- and Krüppel-like transcription factors. Genome Biology 2003, 4: 206. PMID: 12620113, PMCID: PMC151296, DOI: 10.1186/gb-2003-4-2-206.
- Fernandez-Zapico M, Bramati P, Zakaria S, Kaczynski J, Urrutia R. Fundamentals of Transcription Factors and their Impact on Pancreatic Development and Cancer. Pancreatology 2003, 3: 276-283. PMID: 12890989, DOI: 10.1159/000071765.
- . Functional analysis of basic transcription element (BTE)-binding protein (BTEB) 3 and BTEB4, a novel Sp1-like protein, reveals a subfamily of transcriptional repressors for the BTE site of the cytochrome P4501A1 gene promoter. Biochemical Journal 2002, 366: 873-882. PMID: 12036432, PMCID: PMC1222816, DOI: 10.1042/bj20020388.
- Fernandez-Zapico M, Kaczynski J, Urrutia R. Pancreatic cancer research: challenges, opportunities, and recent developments. Current Opinion In Gastroenterology 2002, 18: 563-567. PMID: 17033334, DOI: 10.1097/00001574-200209000-00007.
- . Signaling disrupts mSin3A binding to the Mad1‐like Sin3‐interacting domain of TIEG2, an Sp1‐like repressor. The EMBO Journal 2002, 21: 2451-2460. PMID: 12006497, PMCID: PMC126002, DOI: 10.1093/emboj/21.10.2451.
- Urrutia R, Conley A, Ellenrieder V, Kaczynski J, DiMagno E. Pancreatic Cancer: Cellular and Molecular Mechanisms. 2002, 383-391. DOI: 10.1016/b0-12-227555-1/00174-x.
- . A Conserved α-Helical Motif Mediates the Interaction of Sp1-Like Transcriptional Repressors with the Corepressor mSin3A. Molecular And Cellular Biology 2001, 21: 5041-5049. PMID: 11438660, PMCID: PMC87230, DOI: 10.1128/mcb.21.15.5041-5049.2001.
- . The Sp1-like Protein BTEB3 Inhibits Transcription via the Basic Transcription Element Box by Interacting with mSin3A and HDAC-1 Co-repressors and Competing with Sp1*. Journal Of Biological Chemistry 2001, 276: 36749-36756. PMID: 11477107, DOI: 10.1074/jbc.m105831200.
- ELLENRIEDER V, ZHANG J, KACZYNSKI J, URRUTIA R. The activity of the TGFβ-inducible transcription factor TIEG2 is antagonized by the proliferative EGFR-MEK-ERK signaling pathway. Gastroenterology 2001, 120: a497-a497. DOI: 10.1016/s0016-5085(01)82467-7.
- CONLEY A, KACZYNSKI J, ELLENRIEDER V, URRUTIA R. Four different Sp1-like proteins bind to the BTE box element present in the promoter of the carcinogen encoding enzyme P4501A1 gene. Gastroenterology 2001, 120: a340-a340. DOI: 10.1016/s0016-5085(01)81692-9.
- KACZYNSKI J, ZHANG J, STROOPE A, URRUTIA R. A novel mechanism for the regulation of the carcinogen-metabolizing enzyme CYP1A1 gene promoter in pancreatic cells. Gastroenterology 2001, 120: a339-a339. DOI: 10.1016/s0016-5085(01)81688-7.
- ZHANG J, MONCRIEFFE M, KACZYNSKI J, PRENDERGAST F, URRUTIA R. Molecular mechanisms of transcriptional repression shared by the growth regulatory Sp1-like proteins and the tumor suppressor Mad1. Gastroenterology 2001, 120: a139-a139. DOI: 10.1016/s0016-5085(01)80685-5.
- Ellenrieder V, Zhang J, Kaczynski J, Urrutia R. The activity of the TGFβ-inducible transcription factor TIEG2 is antagonized by the proliferative EGFR-MEK-ERK signaling pathway. Gastroenterology 2001, 120: a497. DOI: 10.1016/s0016-5085(08)82467-5.
- Kaczynski J, Zhang J, Stroope A, Urrutia R. A novel mechanism for the regulation of the carcinogen-metabolizing enzyme CYP1A1 gene promoter in pancreatic cells. Gastroenterology 2001, 120: a339. DOI: 10.1016/s0016-5085(08)81688-5.
- Conley A, Kaczynski J, Ellenrieder V, Urrutia R. Four different Sp1-like proteins bind to the BTE box element present in the promoter of the carcinogen encoding enzyme P4501A1 gene. Gastroenterology 2001, 120: a340. DOI: 10.1016/s0016-5085(08)81692-7.
- Zhang J, Moncrieffe M, Kaczynski J, Prendergast F, Urrutia R. Molecular mechanisms of transcriptional repression shared by the growth regulatory Sp1-like proteins and the tumor suppressor Mad1. Gastroenterology 2001, 120: a139. DOI: 10.1016/s0016-5085(08)80685-3.
- Hedin K, Kaczynski J, Gibson M, Urrutia R. Transcription factors in cell biology, surgery, and transplantation. Surgery 2000, 128: 1-5. PMID: 10876177, DOI: 10.1067/msy.2000.106426.
- Kaczynski J, Urrutia R. BTEB3, a novel Sp1-like protein represses gene expression by a dual mechanism: Direct repression and competition with the activator Sp1. Gastroenterology 2000, 118: a639. DOI: 10.1016/s0016-5085(00)84696-x.
- Ellenrieder V, Kaczynski J, Hedin K, Urrutia R. Detailed domain structure and MAP kinase-mediated phosphorylation of the growth suppressor transcription factor, TIEG2. Gastroenterology 2000, 118: a639. DOI: 10.1016/s0016-5085(00)84693-4.
Biography
Joanna A. Gibson, MD, PhD, a pathologist, still remembers details from a lecture she heard as a graduate teaching assistant in the Mayo Clinic’s MD-PhD program in Rochester, Minn. “I remember the lecturer explained how cancer cells behaved in the body, and then showed an image of those cancer cells within a biopsy sample projected on a slide—and it just clicked for me,” Dr. Gibson says. “I loved how pathology brought the science and the patient care aspects together.” Today, Dr. Gibson specializes in diagnosing gastrointestinal and liver diseases, including cancers, at Yale Medicine.
“For each patient case, I read through the medical history and notes to get a good idea in my mind about who the patient is,” Dr. Gibson says. Even when dealing with a high volume of biopsies, taking these extra moments to put together a patient’s story is crucial, she says.
As an assistant professor of pathology at Yale School of Medicine, Dr. Gibson also conducts research on the pathology of gastrointestinal diseases.
Titles
- Associate Professor of Pathology
- Director of Quality and Patient Safety, Pathology
Education & Training
- FellowshipBrigham & Women's Hospital (2009)
- ResidencyBrigham & Women's Hospital (2008)
- PhDMayo Clinic College of Medicine (2004)
- MDMayo Clinic College of Medicine (2004)
Languages Spoken
- English
Additional Information
- Aladelokun O, Lu L, Zheng J, Yan H, Jain A, Gibson J, Khan S, Johnson C. Growth characteristics of HCT116 xenografts lacking asparagine synthetase vary according to sex. Human Genomics 2024, 18: 67. PMID: 38886847, PMCID: PMC11184737, DOI: 10.1186/s40246-024-00635-3.
- Singh V, Mezzacappa C, Gershkovich P, Di Giovanna J, Ganzak A, Gibson J, Sinard J, Xicola RM, Llor X. Systems approach to enhance Lynch syndrome diagnosis through tumour testing. Journal Of Medical Genetics 2022, 60: 533-539. PMID: 36115663, PMCID: PMC10020126, DOI: 10.1136/jmg-2022-108770.
- Giner-Calabuig M, De Leon S, Vidal-Pedrola G, Fehlmann T, Ukaegbu C, Gibson J, Picó M, Alenda C, Reyes J, Ortega S, LLado C, de la Torre Rubio P, Obrador-Hevia A, Castillejo A, Soto J, Castellví-Bel S, Syngal S, Stoffel E, Ellis N, Jover R, Llor X, Xicola R. Tu1100: HETEROZYGOUS MUTATIONS IN DNA REPAIR GENES CONFER GENETIC SUSCEPTIILITY TO COLORECTAL CANCER AMONG LYNCH-LIKE CASES. Gastroenterology 2022, 162: s-883. DOI: 10.1016/s0016-5085(22)62088-2.
- Matsumoto N, Barbieri A, Gershkovich P, Cecchini M, Gibson J. QIM22-192: Mismatch Repair Protein Immunohistochemistry: Quality of Mismatch Repair Deficiency Detection. Journal Of The National Comprehensive Cancer Network 2022, 20: qim22-192. DOI: 10.6004/jnccn.2021.7192.
- Giner-Calabuig M, De Leon S, Wang J, Fehlmann TD, Ukaegbu C, Gibson J, Alustiza-Fernandez M, Pico MD, Alenda C, Herraiz M, Carrillo-Palau M, Salces I, Reyes J, Ortega SP, Obrador-Hevia A, Cecchini M, Syngal S, Stoffel E, Ellis NA, Sweasy J, Jover R, Llor X, Xicola RM. Mutational signature profiling classifies subtypes of clinically different mismatch-repair-deficient tumours with a differential immunogenic response potential. British Journal Of Cancer 2022, 126: 1595-1603. PMID: 35197584, PMCID: PMC9130322, DOI: 10.1038/s41416-022-01754-1.
- Li H, Zhang X, Finberg KE, Walther Z, Jain D, Gibson J. Pathogenic BRCA2 germline variants in combined hepatocellular‐cholangiocarcinoma. Pathology International 2021, 72: 138-140. PMID: 34808016, DOI: 10.1111/pin.13188.
- Gibson JA, Finberg KE, Nalbantoglu I, Cecchini M, Ganzak A, Walther Z, Sklar JL, Eder JP, Goldberg SB. Yale Cancer Center Precision Medicine Tumor Board: molecular findings alter a diagnosis and treatment plan. The Lancet Oncology 2021, 22: 306-307. PMID: 33662283, DOI: 10.1016/s1470-2045(20)30683-5.
- Morrow JS, Gershkovich P, Gibson J, Gilshannon M, Kowalski D, Levi AW, Nguyen DX, Rimm DL, Xu ML, Sinard J. Measuring Faculty Effort: A Quantitative Approach That Aligns Personal and Institutional Goals in Pathology at Yale. Academic Pathology 2021, 8: 23742895211047985. PMID: 34646939, PMCID: PMC8504692, DOI: 10.1177/23742895211047985.
- Singh V, Ganzak A, Gershkovich P, Gibson J, Llor X. 1 IMPROVING LYNCH SYNDROME IDENTIFICATION THROUGH THE IMPLEMENTATION OF ENHANCED TUMOR TESTING AND A COMPREHENSIVE SYSTEMS APPROACH. Gastroenterology 2020, 158: s-1. DOI: 10.1016/s0016-5085(20)30682-x.
- Patel N, Barbieri A, Gibson J. Neuroendocrine Tumors of the Gastrointestinal Tract and Pancreas. Surgical Pathology Clinics 2019, 12: 1021-1044. PMID: 31672292, DOI: 10.1016/j.path.2019.08.007.
- Guerra MT, Florentino RM, Franca A, Lima Filho AC, Dos Santos ML, Fonseca RC, Lemos FO, Fonseca MC, Kruglov E, Mennone A, Njei B, Gibson J, Guan F, Cheng YC, Ananthanarayanan M, Gu J, Jiang J, Zhao H, Lima CX, Vidigal PT, Oliveira AG, Nathanson MH, Leite MF. Expression of the type 3 InsP3 receptor is a final common event in the development of hepatocellular carcinoma. Gut 2019, 68: 1676. PMID: 31315892, PMCID: PMC7087395, DOI: 10.1136/gutjnl-2018-317811.
- Paulson N, Gibson J, Glusac E. Perianal and perineal keratoacanthoma: Two cases demonstrating histologic similarity to subungual keratoacanthoma. Journal Of Cutaneous Pathology 2019, 46: 794-797. PMID: 31148238, DOI: 10.1111/cup.13518.
- Celli R, Hui P, Triscott H, Bogardus S, Gibson J, Hwang M, Robert ME. Clinical Insignficance of Monoclonal T-Cell Populations and Duodenal Intraepithelial T-Cell Phenotypes in Celiac and Nonceliac Patients. The American Journal Of Surgical Pathology 2019, 43: 151-160. PMID: 30334829, DOI: 10.1097/pas.0000000000001172.
- Gibson J, Odze R. 5 Tissue Sampling, Specimen Handling, and Laboratory Processing. 2019, 51-68.e6. DOI: 10.1016/b978-0-323-41509-5.00005-0.
- Rodriguez NJ, Gupta N, Gibson J. Autoimmune Enteropathy in an Ulcerative Colitis Patient. ACG Case Reports Journal 2018, 5: e78. PMID: 30465008, PMCID: PMC6224868, DOI: 10.14309/crj.2018.78.
- Chaunzwa TL, O'Shea J, Boggs NA, Schwartz JI, Gibson J, Gielissen KA. Hemolytic Anemia and Gastric Carcinoid in a Russian Seafarer: Highlighting the Role of Diagnostic Technologies in Modern Clinical Practice. The Yale Journal Of Biology And Medicine 2018, 91: 243-246. PMID: 30258311, PMCID: PMC6153615.
- Celli R, Barbieri AL, Colunga M, Sinard J, Gibson JA. Optimal Intraoperative Assessment of Gastric Margins. American Journal Of Clinical Pathology 2018, 150: 353-363. PMID: 30020407, DOI: 10.1093/ajcp/aqy062.
- Benedict M, Gibson J, Zhang X. Epithelioid Angiosarcoma: An Unusual Cause of Gastrointestinal Bleeding. International Journal Of Surgical Pathology 2018, 27: 277-279. PMID: 29944034, DOI: 10.1177/1066896918784180.
- Gopal P, Gibson JA, Lisovsky M, Nalbantoglu I. Unique causes of esophageal inflammation: a histopathologic perspective. Annals Of The New York Academy Of Sciences 2018, 1434: 219-226. PMID: 29766506, DOI: 10.1111/nyas.13732.
- Rodriguez N, Gupta N, Gibson J. Autoimmune Enteropathy in an Ulcerative Colitis Patient. ACG Case Reports Journal 2018, 5: e781-3. DOI: 10.14309/02075970-201805110-00003.
- Rodriguez N, Gupta N, Gibson J. Autoimmune Enteropathy in an Ulcerative Colitis Patient. ACG Case Reports Journal 2018, 5: e78. DOI: 10.14309/02075970-201805000-00078.
- Cenaj O, Gibson J, Odze RD. Clinicopathologic and outcome study of sessile serrated adenomas/polyps with serrated versus intestinal dysplasia. Modern Pathology 2017, 31: 633-642. PMID: 29271414, DOI: 10.1038/modpathol.2017.169.
- Boddupalli CS, Nair S, Gray SM, Nowyhed HN, Verma R, Gibson JA, Abraham C, Narayan D, Vasquez J, Hedrick CC, Flavell RA, Dhodapkar KM, Kaech SM, Dhodapkar MV. ABC transporters and NR4A1 identify a quiescent subset of tissue-resident memory T cells. Journal Of Clinical Investigation 2016, 126: 3905-3916. PMID: 27617863, PMCID: PMC5096804, DOI: 10.1172/jci85329.
- Parikh ND, Gibson J, Nagar A, Ahmed AA, Aslanian HR. Confocal laser endomicroscopy features of sessile serrated adenomas/polyps. United European Gastroenterology Journal 2016, 4: 599-603. PMID: 27536371, PMCID: PMC4971791, DOI: 10.1177/2050640615621819.
- Gibson JA, Odze RD. Pathology of premalignant colorectal neoplasia. Digestive Endoscopy 2016, 28: 312-323. PMID: 26861656, DOI: 10.1111/den.12633.
- Parikh ND, Gibson J, Aslanian H. Gastric Fundic Gland Adenocarcinoma With Chief Cell Differentiation. Clinical Gastroenterology And Hepatology 2015, 13: a17-a18. PMID: 26215839, PMCID: PMC4829391, DOI: 10.1016/j.cgh.2015.07.023.
- Shen J, Gibson JA, Schulte S, Khurana H, Farraye FA, Levine J, Burakoff R, Cerda S, Qazi T, Hamilton M, Srivastava A, Odze RD. Clinical, pathologic, and outcome study of hyperplastic and sessile serrated polyps in inflammatory bowel disease. Human Pathology 2015, 46: 1548-1556. PMID: 26297256, DOI: 10.1016/j.humpath.2015.06.019.
- Sethi A, Jain D, Roland BC, Kinzel J, Gibson J, Schrader R, Hanson JA. Performing Colonic Mast Cell Counts in Patients With Chronic Diarrhea of Unknown Etiology Has Limited Diagnostic Use. Archives Of Pathology & Laboratory Medicine 2015, 139: 225-32. PMID: 25611105, DOI: 10.5858/arpa.2013-0594-oa.
- Rustagi T, Mansoor MS, Gibson JA, Kapadia CR. Pseudomelanosis of Stomach, Duodenum, and Jejunum. Journal Of Clinical Gastroenterology 2015, 49: 124-126. PMID: 24492404, DOI: 10.1097/mcg.0000000000000081.
- Milam A, Maher SE, Gibson JA, Lebastchi J, Wen L, Ruddle NH, Herold KC, Bothwell AL. A Humanized Mouse Model of Autoimmune Insulitis. Diabetes 2014, 63: 1712-1724. PMID: 24478396, PMCID: PMC3994947, DOI: 10.2337/db13-1141.
- Gibson J, Lacy J, Matloff E, Robert M. Microsatellite Instability Testing in Colorectal Carcinoma: A Practical Guide. Clinical Gastroenterology And Hepatology 2014, 12: 171-176.e1. PMID: 24434275, DOI: 10.1016/j.cgh.2013.11.001.
- Batts KP, Ketover S, Kakar S, Krasinskas AM, Mitchell KA, Wilcox R, Westerhoff M, Rank J, Gibson J, Mattia AR, Cummings OW, Davison JM, Naini BV, Dry SM, Yantiss RK. Appropriate Use of Special Stains for Identifying Helicobacter pylori. The American Journal Of Surgical Pathology 2013, 37: e12-e22. PMID: 24141174, DOI: 10.1097/pas.0000000000000097.
- Virk RK, Van Dyke AL, Finkelstein A, Prasad A, Gibson J, Hui P, Theoharis CG, Carling T, Roman SA, Sosa JA, Udelsman R, Prasad ML. BRAF V600E mutation in papillary thyroid microcarcinoma: a genotype–phenotype correlation. Modern Pathology 2012, 26: 62-70. PMID: 22918165, DOI: 10.1038/modpathol.2012.152.
- Gibson JA, Odze RD. Pathology of Diseases that Cause Upper Gastrointestinal Tract Bleeding. Gastrointestinal Endoscopy Clinics Of North America 2011, 21: 583-596. PMID: 21944412, DOI: 10.1016/j.giec.2011.07.006.
- Gibson JA, Hahn HP, Shahsafaei A, Odze RD. MUC Expression in Hyperplastic and Serrated Colonic Polyps. The American Journal Of Surgical Pathology 2011, 35: 742-749. PMID: 21490447, DOI: 10.1097/pas.0b013e31821537a2.
- Gibson JA, Hornick JL. Mucosal Schwann Cell “Hamartoma”. The American Journal Of Surgical Pathology 2009, 33: 781-787. PMID: 19065103, DOI: 10.1097/pas.0b013e31818dd6ca.
- Yu H, Gibson JA, Pinkus GS, Hornick JL. Podoplanin (D2-40) Is a Novel Marker for Follicular Dendritic Cell Tumors. American Journal Of Clinical Pathology 2007, 128: 776-782. PMID: 17951199, DOI: 10.1309/7p8u659jbjcv6eeu.
- Kaczynski J, Cook T, Urrutia R. Sp1- and Krüppel-like transcription factors. Genome Biology 2003, 4: 206. PMID: 12620113, PMCID: PMC151296, DOI: 10.1186/gb-2003-4-2-206.
- Fernandez-Zapico M, Bramati P, Zakaria S, Kaczynski J, Urrutia R. Fundamentals of Transcription Factors and their Impact on Pancreatic Development and Cancer. Pancreatology 2003, 3: 276-283. PMID: 12890989, DOI: 10.1159/000071765.
- . Functional analysis of basic transcription element (BTE)-binding protein (BTEB) 3 and BTEB4, a novel Sp1-like protein, reveals a subfamily of transcriptional repressors for the BTE site of the cytochrome P4501A1 gene promoter. Biochemical Journal 2002, 366: 873-882. PMID: 12036432, PMCID: PMC1222816, DOI: 10.1042/bj20020388.
- Fernandez-Zapico M, Kaczynski J, Urrutia R. Pancreatic cancer research: challenges, opportunities, and recent developments. Current Opinion In Gastroenterology 2002, 18: 563-567. PMID: 17033334, DOI: 10.1097/00001574-200209000-00007.
- . Signaling disrupts mSin3A binding to the Mad1‐like Sin3‐interacting domain of TIEG2, an Sp1‐like repressor. The EMBO Journal 2002, 21: 2451-2460. PMID: 12006497, PMCID: PMC126002, DOI: 10.1093/emboj/21.10.2451.
- Urrutia R, Conley A, Ellenrieder V, Kaczynski J, DiMagno E. Pancreatic Cancer: Cellular and Molecular Mechanisms. 2002, 383-391. DOI: 10.1016/b0-12-227555-1/00174-x.
- . A Conserved α-Helical Motif Mediates the Interaction of Sp1-Like Transcriptional Repressors with the Corepressor mSin3A. Molecular And Cellular Biology 2001, 21: 5041-5049. PMID: 11438660, PMCID: PMC87230, DOI: 10.1128/mcb.21.15.5041-5049.2001.
- . The Sp1-like Protein BTEB3 Inhibits Transcription via the Basic Transcription Element Box by Interacting with mSin3A and HDAC-1 Co-repressors and Competing with Sp1*. Journal Of Biological Chemistry 2001, 276: 36749-36756. PMID: 11477107, DOI: 10.1074/jbc.m105831200.
- ELLENRIEDER V, ZHANG J, KACZYNSKI J, URRUTIA R. The activity of the TGFβ-inducible transcription factor TIEG2 is antagonized by the proliferative EGFR-MEK-ERK signaling pathway. Gastroenterology 2001, 120: a497-a497. DOI: 10.1016/s0016-5085(01)82467-7.
- CONLEY A, KACZYNSKI J, ELLENRIEDER V, URRUTIA R. Four different Sp1-like proteins bind to the BTE box element present in the promoter of the carcinogen encoding enzyme P4501A1 gene. Gastroenterology 2001, 120: a340-a340. DOI: 10.1016/s0016-5085(01)81692-9.
- KACZYNSKI J, ZHANG J, STROOPE A, URRUTIA R. A novel mechanism for the regulation of the carcinogen-metabolizing enzyme CYP1A1 gene promoter in pancreatic cells. Gastroenterology 2001, 120: a339-a339. DOI: 10.1016/s0016-5085(01)81688-7.
- ZHANG J, MONCRIEFFE M, KACZYNSKI J, PRENDERGAST F, URRUTIA R. Molecular mechanisms of transcriptional repression shared by the growth regulatory Sp1-like proteins and the tumor suppressor Mad1. Gastroenterology 2001, 120: a139-a139. DOI: 10.1016/s0016-5085(01)80685-5.
- Ellenrieder V, Zhang J, Kaczynski J, Urrutia R. The activity of the TGFβ-inducible transcription factor TIEG2 is antagonized by the proliferative EGFR-MEK-ERK signaling pathway. Gastroenterology 2001, 120: a497. DOI: 10.1016/s0016-5085(08)82467-5.
- Kaczynski J, Zhang J, Stroope A, Urrutia R. A novel mechanism for the regulation of the carcinogen-metabolizing enzyme CYP1A1 gene promoter in pancreatic cells. Gastroenterology 2001, 120: a339. DOI: 10.1016/s0016-5085(08)81688-5.
- Conley A, Kaczynski J, Ellenrieder V, Urrutia R. Four different Sp1-like proteins bind to the BTE box element present in the promoter of the carcinogen encoding enzyme P4501A1 gene. Gastroenterology 2001, 120: a340. DOI: 10.1016/s0016-5085(08)81692-7.
- Zhang J, Moncrieffe M, Kaczynski J, Prendergast F, Urrutia R. Molecular mechanisms of transcriptional repression shared by the growth regulatory Sp1-like proteins and the tumor suppressor Mad1. Gastroenterology 2001, 120: a139. DOI: 10.1016/s0016-5085(08)80685-3.
- Hedin K, Kaczynski J, Gibson M, Urrutia R. Transcription factors in cell biology, surgery, and transplantation. Surgery 2000, 128: 1-5. PMID: 10876177, DOI: 10.1067/msy.2000.106426.
- Kaczynski J, Urrutia R. BTEB3, a novel Sp1-like protein represses gene expression by a dual mechanism: Direct repression and competition with the activator Sp1. Gastroenterology 2000, 118: a639. DOI: 10.1016/s0016-5085(00)84696-x.
- Ellenrieder V, Kaczynski J, Hedin K, Urrutia R. Detailed domain structure and MAP kinase-mediated phosphorylation of the growth suppressor transcription factor, TIEG2. Gastroenterology 2000, 118: a639. DOI: 10.1016/s0016-5085(00)84693-4.