- Winchester Center for Lung DiseaseFitkin Memorial Pavilion789 Howard Avenue, Ste 2nd floorNew Haven, CT 06519
- Winchester Center for Lung DiseaseNorth Haven Medical Center6 Devine StreetNorth Haven, CT 06473
Geoffrey Chupp, MD
Biography
Geoffrey Chupp, MD, is a pulmonologist who specializes in lung diseases that affect the airway, including severe asthma, Chronic Obstructive Pulmonary Disease (COPD), bronchiolitis, autoimmune airway diseases, and airway diseases that have not been classified. He also specializes in eosinophilic lung diseases such as eosinophilic pneumonia, eosinophilic granulomatosis with polyangiitis (EGPA), and Allergic Bronchopulmonary Aspergillosis (ABPA).
He often helps patients who have complex disease that has been difficult to treat.
“I wanted to pursue a career in medicine to comfort people who are sick and discover the cause or causes of their disease,” says Dr. Chupp. Working with pulmonary patients is especially rewarding for a doctor, he adds. “It crosses all segments of society, so I get to meet lots of interesting people.”
Dr. Chupp came to Yale in 1997 and developed the Yale Center for Asthma & Airways Disease (YCAAD), a multidisciplinary clinical program that he still directs. The center cares for a broad spectrum of conditions and has helped patients with conditions that are difficult to diagnose, sometimes because of a co-occurring illness such as gastroesophageal reflux or sinusitis, and provides treatments that may not be available elsewhere. “We have novel biologic treatments and access to clinical trials for these patients,” he says.
Up to 20 clinical trials are active at any given time at YCAAD. This research has helped put Yale Medicine on the cutting edge of individualized asthma therapy and precision medicine for patients with asthma. “We see a future where we will be identifying a patient’s particular genetic risk factors and the molecular signals that are driving their particular disease,” says Dr. Chupp. “We will develop a combination of treatments that is personalized for every patient; it will include lifestyle recommendations, inhaled therapies, and biologic therapies that will maximally manage their disease without guesswork.”
Titles
- Professor of Medicine (Pulmonary, Critical Care and Sleep Medicine )
- Director, Yale Center for Asthma and Airways Disease (YCAAD), Pulmonary, Critical Care & Sleep Medicine
- Director, Pulmonary Function Laboratory, Yale New Haven Hospital, Pulmonary, Critical Care & Sleep Medicine
Education & Training
- MAYale University, Privatim (2017)
- ResidencyNew England Medical Center (2003)
- FellowBoston University School of Medicine (1997)
- ResidentTufts University/New England Medical Center (1993)
- InternTufts-New England Medical Center (1991)
- MDGeorge Washington University (1990)
- BSTufts University (1986)
- InternshipNew England Medical Center
Additional Information
- Yale Technology Summit: Technology Innovations Pitch Competition Award Second Place: (2017)
- Connecticut Magazine Top Docs 2016: Connecticut Magazine (2016)
- Connecticut Magazine Top Docs 2015: Connecticut Magazine (2015)
- Hero of Yale New Haven Hospital Award: (2009)
- Distinguished Service Award: Yale New Haven Hospital (2008)
- Distinguished Service Award: Yale New Haven Hospital (2007)
- Excellence in Teaching Award: Pulmonary and Critical Care Fellows), Division of Pulmonary and Critical Care Medicine (2006)
- Distinguished Service Award: Yale New Haven Hospital (2006)
- Excellence in Teaching Award: Pulmonary and Critical Care Fellows (2002)
- Loan Repayment Award: National Institutes of Health (2002)
- Skowasch D, Pavord I, Chupp G, Jackson D, Muccino D, Forth R, Kwiatek J, Vichiendilokkul A, Jackson D. Twice-yearly Depemokimab (Depe) Reduces Exacerbations and Improves Quality of Life (QoL) in Patients (Pts) With Uncontrolled Asthma Symptoms at Baseline (BL): Subgroup Analyses of the Phase III SWIFT-1/2 Studies. Pneumologie 2026, 80: s178-s179. DOI: 10.1055/s-0046-1816513.
- Denlinger L, Israel E, Moore W, Georas S, Wright R, Castro M, Peden D, Anstrom K, Bleecker E, Alexander L, Cahill K, Cardet J, Carr T, Cedano J, Chen A, Chupp G, Comhair S, DiMango E, Erzurum S, Fahy J, Fajt M, Gaston B, Jackson D, Jain S, Jarjour N, Kenyon N, Kraft M, Krishnan J, Kumar R, Lugogo N, Martinez F, Marquis M, Pappalardo A, Phipatanakul W, Rank M, Rosenberg S, Salciccioli J, Sanchez M, Smith L, Sumino K, Szefler S, Tang M, Vijayanand P, Wechsler M, Wenzel S, White S, Zeki A, Ivanova A, Bacharier L, Akuthota P, Team N, Bleecker E, Carr T, Moore W, Rank M, Camacho G, Gerald L, Hastie A, Krings J, Martinez F, Merchen J, Meyers D, Nirendran N, Ortega V, Pippins A, Rusk A, Schunk R, Skeps R, Simmons T, Williamson P, Zein J, Israel E, Cardet J, DiMango E, Phipatanakul W, Bailey J, Banzon T, Bartnikas L, Baxi S, Betapudi V, Brick I, Casale T, Cinelli M, Crestani E, Cunningham A, Esty B, Fandozzi ;, Fernandez J, Fitzpatrick E, Flam B, Forth V, Gaffin J, Gentile K, Gueye-Ndiaye S, Haley K, Heromin R, Hauptmann M, Kaage T, Kelly M, Kraemer M, LaBere B, Lai P, Le M, Ledford D, Lee J, Lee J, Lockey R, Macginnitie A, McCarty K, Moss K, Mukharesh L, Pistenmaa A, Pepper A, Pimental M, Queheillalt D, Robinson A, Salciccioli J, Saroya T, Smith C, Trevedi M, Trippa L, Tulchinsky A, Vitiello A, Yee C, Zakar K, White T, Kumar R, Moy J, Rosenberg S, Aalemansour H, Buechler K, Carter T, Fu J, Hixon J, Jackson C, Ji Y, Johnson C, Kalhan R, Kane J, Kaur O, Li G, Lippner E, Makhija M, Maleckar S, Naureckas E, Nyenhuis S, Peters A, Press V, Qureshi M, Ryba D, Sheng J, Smith L, Xu B, Wechsler M, Szefler S, Chupp G, Holguin F, Kraft M, Liu A, Rogers L, Anderson D, Belimezova S, Bitzan J, Bose S, Brock J, Sanchez J, Clark B, Cohn L, Cotarian A, Cruse M, Eisenberg E, Estrom J, Glassmeyer I, Villalobos J, Grant N, Gruberg B, Guntur V, Hay O, Hills A, Hsieh J, Kessler J, Kolakowski C, Miyazawa N, Pak J, Pruitt D, Rhoads S, Sharma S, Stevens A, Tippin B, Valente C, Vicencio A, Wainscoat C, Weber J, Wessels G, White M, Winnica D, Zeitlin P, Denlinger L, Jarjour N, Krishnan J, Agnihotri N, Bach J, Bires N, DeLisa J, Fichtinger P, Floerke H, Fritz B, Grogan J, Guadarrama A, Hasse W, Jackson D, Kaspari R, Kelley R, Klaus D, Lowell P, Larson L, Norwick L, O’Brien M, Palas T, Pappalardo A, Read E, Schraml A, Schiebler M, Sorkness R, Tattersall M, Wollet L, Gaston B, Erzurum S, Teague W, Chmiel J, Ross K, Aronica M, Beck B, Bendy L, Borish L, Chedraoui C, Comhair S, Davis M, Dix A, Fakhry B, Gammell R, Gluvna A, Hamm E, Heskett M, Hu B, Khatri S, Kirwan J, Kloepfer K, Koo M, Labadia M, Marko A, Matheis N, Mey J, Mulya A, Murphy D, Owensby R, Parker L, Pennington E, Roesch E, Sharp J, Smith C, Solanki N, Veri L, Shifflett K, Yang F, Wenzel S, Lugogo N, Bagheri A, Cislo L, Fajt M, Gauthier M, Hadden M, James P, Mohan A, Moore J, Nouraie S, Ramonell R, Romanek R, Sullivan L, Trudeau J, Zhang M, Akuthota P, Jain S, Vijayanand P, Barry J, Beg N, Brickner H, Alexander L, Diaz D, Jafari Y, McKeon N, Fahy J, Kenyon N, Almario M, Charbit A, Cho L, Gale B, Haczku A, Harper R, Houston T, Kain C, Kivler C, Kuhn B, Liu M, McCourt P, Miller J, Nguyen A, Orain X, Peters M, Plough A, Ramirez K, Rossi L, Schivo M, Singapuri M, Teuber S, Tham T, Tompkins D, Vi J, Zeki A, Castro M, Bacharier L, Sumino K, Atha J, Boomer J, Cahill K, Clover A, Dorman V, Hoffman E, Jackson F, Klinck M, Krings J, Madison J, Quigley J, Quinones T, Saxena S, Sharpe M, Troyer J, Yen-Declue H, Zulich A, Ivanova A, Anstrom K, LaVange L, Bagaason S, Britt A, Bryan H, Burbank A, Chen A, Culpepper C, DeMarcus F, Fenu C, Gotman N, Green R, Harrison L, James J, Kosorok J, Kosorok M, Littleton L, Marquis M, O'Neal W, Peden D, Price R, Quibrera P, Ritz C, Sanchez M, Schwartz S, Slye N, Song T, Wilson N, Croxton T, Lu J, Noel P, Bamdad J, Georas S, Wright R. PrecISE- A Biomarker Stratified Adaptive Trial of 5 Interventions in Severe Asthma: Final Protocol and the Baseline Cohort. The Journal Of Allergy And Clinical Immunology 2026 PMID: 41707916, DOI: 10.1016/j.jaci.2026.02.001.
- Chupp G, Nagase H, Skowasch D, Devouassoux G, Côté A, Jackson D, Jackson D, Wechsler M, Imber V, McGinniss J, K S, Howarth P, Pavord I. Switching to twice-yearly depemokimab from mepolizumab/benralizumab in severe asthma: A multicenter, randomized, double-blind, Phase 3A Clinical Trial (NIMBLE). American Journal Of Respiratory And Critical Care Medicine 2026 PMID: 41738176, DOI: 10.1093/ajrccm/aamag031.
- Kay S, Rajeevan H, Son M, Kwah J, Ramirez M, Liu Y, Wang Z, Yan X, Nino G, Britto C, Chupp G, Gomez J. Sex-biased Gene Expression Underlies Immune Dysfunction in Asthma. American Journal Of Respiratory Cell And Molecular Biology 2025, 73: 884-896. PMID: 40587876, DOI: 10.1165/rcmb.2024-0565oc.
- Zidan E, Ahn J, Kang I, Chupp G, Shin J. SYSTEMATIC REVIEW ON THE PREVALENCE OF IMMUNOGLOBULIN G SUBCLASS DEFICIENCIES IN PATIENTS WITH ASTHMA. Annals Of Allergy Asthma & Immunology 2025, 135: s50. DOI: 10.1016/j.anai.2025.08.156.
- Lugogo N, Carr T, White A, Chupp G, Chase N, Lanz M, Marchese C, Lindsley A, Lal H, Ambrose C. TEZEPELUMAB EFFICACY IN PATIENTS WITH SEVERE, UNCONTROLLED ASTHMA BY EXACERBATION TRIGGERS IN NAVIGATOR AND DIRECTION. Annals Of Allergy Asthma & Immunology 2025, 135: s47. DOI: 10.1016/j.anai.2025.08.150.
- CHUPP G, BERNSTEIN D, JACQUES L, ZHU C, VICHIENDILOKKUL A, HOWARTH P, KWIATEK J, WECHSLER M, PAVORD I. TWICE-YEARLY DEPEMOKIMAB REDUCES NEED FOR BURST ORAL CORTICOSTEROID USE IN PATIENTS WITH ASTHMA: POSTHOC ANALYSES OF THE PHASE III SWIFT-1/2 STUDIES. Chest 2025, 168: a1-a3. DOI: 10.1016/j.chest.2025.07.007.
- CRINER G, CHUPP G, HAN M, SINGH D, MARCHESE C, MOLFINO N, MATSUNAGA Y, PONNARAMBIL S, AMBROSE C. EFFECT OF TEZEPELUMAB ON SYSTEMIC CORTICOSTEROID USE FOR EXACERBATIONS IN PATIENTS WITH MODERATE TO VERY SEVERE COPD BY BLOOD EOSINOPHIL COUNT. Chest 2025, 168: a7259-a7263. DOI: 10.1016/j.chest.2025.09.078.
- Chupp G, Hui C, Christenson S, Israel E, Janssens W, Kocks J, Siddiqui S, Haughney J, Topole E, Da Silva C, Bolton C. Survey evaluating CompEx Asthma components, and current and future digital enablers. 2025, pa1483. DOI: 10.1183/13993003.congress-2025.pa1483.
- Canonica G, Bagnasco D, Lee J, Chupp G, Schleich F, Oppenheimer J, Zhang L, Alfonso-Cristancho R, Howarth P. Mepolizumab in patients with severe asthma and blood eosinophil counts between 150 and 300 cells per µL: benefits at two years. ERJ Open Research 2025, 11: 01390-2024. PMID: 41220814, PMCID: PMC12598589, DOI: 10.1183/23120541.01390-2024.
- Impact of Demographics on Mepolizumab Effectiveness in Severe Asthma: One-Year REALITI-A SubanalysisChupp G, Heaney L, Pelaia G, Almonacid C, Maxwell A, Zhang L, Alfonso-Cristancho R, Howarth P, Brusselle G. Impact of Demographics on Mepolizumab Effectiveness in Severe Asthma: One-Year REALITI-A Subanalysis. The Journal Of Allergy And Clinical Immunology In Practice 2025, 13: 3286-3295. PMID: 40780384, DOI: 10.1016/j.jaip.2025.07.049.
- Zielonka J, Kay S, Chupp G, Gomez J. The Role of Non-coding RNAs in Asthma T2-high and T2-low Endotypes. American Journal Of Respiratory And Critical Care Medicine 2025, 211: a3430-a3430. DOI: 10.1164/ajrccm.2025.211.abstracts.a3430.
- Hadikhani P, Yan X, Chupp G, Liu Q, Ban G, Piparia S, Mcgeachie M, Sharma R, Weiss S, Kho A, Tantisira K. Asthma Exacerbations: Integrative Analysis of Mirna Activity in Using Single-cell Transcriptomics. American Journal Of Respiratory And Critical Care Medicine 2025, 211: a7773-a7773. DOI: 10.1164/ajrccm.2025.211.abstracts.a7773.
- Pavord I, Chupp G, Jackson D, Muccino D, Forth R, Kwiatek J, Vichiendilokkul A, Jackson D. Twice-yearly Depemokimab Reduces Exacerbations and Improves Quality of Life in Patients With Uncontrolled Asthma Symptoms at Baseline: Subgroup Analyses of the Phase III SWIFT-1/2 Studies. American Journal Of Respiratory And Critical Care Medicine 2025, 211: a5234-a5234. DOI: 10.1164/ajrccm.2025.211.abstracts.a5234.
- Criner G, Chupp G, Han M, Martin N, Molfino N, Ambrose C, Sindhwani N, Ponnarambil S. Improvements in St George's Respiratory Questionnaire Domain Scores With Tezepelumab Versus Placebo in Patients With Moderate to Very Severe Chronic Obstructive Pulmonary Disease: Results From the Phase 2a COURSE Study. American Journal Of Respiratory And Critical Care Medicine 2025, 211: a4031-a4031. DOI: 10.1164/ajrccm.2025.211.abstracts.a4031.
- Han M, Drummond M, Criner G, Chupp G, Martin N, Molfino N, Ambrose C, Sindhwani N, Ponnarambil S. Effect of Tezepelumab on Exacerbations in Patients With Moderate to Very Severe Chronic Obstructive Pulmonary Disease Based on Inclusion or Exclusion of Antibiotic Use in the Definition of Moderate Exacerbations: Data From the Phase 2a COURSE Study. American Journal Of Respiratory And Critical Care Medicine 2025, 211: a4026-a4026. DOI: 10.1164/ajrccm.2025.211.abstracts.a4026.
- Bazan I, Chupp G, Duan L, Pelletier M, Carstens D, Ambrose C. The Impact of Race-Neutral Reference Pulmonary Function Equations Among Us Patients With Severe Asthma: Results from the Chronicle Study. American Journal Of Respiratory And Critical Care Medicine 2025, 211: a1047-a1047. DOI: 10.1164/ajrccm.2025.211.abstracts.a1047.
- Zaeh S, Hay O, Zimmerman Z, Chupp G, Eakin M. Barriers and Facilitators to Transitioning to Maintenance and Reliever Therapy for Patients With Moderate to Severe Asthma. American Journal Of Respiratory And Critical Care Medicine 2025, 211: a1473-a1473. DOI: 10.1164/ajrccm.2025.211.abstracts.a1473.
- Liu M, Chaudhuri R, Chupp G, Heaney L, Lee J, Pilette C, Brusselle G, Alfonso-Cristancho R, Zhang L, Howarth P, Kumar A. Impact of atopic status, prior omalizumab use and baseline blood eosinophil count alone and in combination with total serum IgE on maintenance OCS reduction outcomes in patients with severe asthma treated with mepolizumab in the REALITI-A study. Revue Française D'Allergologie Et D'Immunologie Clinique 2025, 65: 104319. DOI: 10.1016/j.reval.2025.104319.
- Caruso C, Canonica G, Patel M, Smith A, Liu M, Alfonso-Cristancho R, Price R, Jakes R, Demetriou L, Valero A, Köhler T, Pilette C, Chupp G, Brusselle G, Howarth P. Prospective REALITI-A Study 2-Year Real-World Benefits of Mepolizumab in Severe Asthma. CHEST Pulmonary 2025, 3: 100107. DOI: 10.1016/j.chpulm.2024.100107.
- Cardet J, Bailey J, Hurley L, Maher N, Staton E, Yawn B, Zaeh S, Israel E, investigators; O, Apter A, Bradford P, Calderon-Candelario R, Carroll J, Chupp G, Cohen R, Ericson B, Fuhlbrigge A, Kaplan B, Kruse J, Nazario S, Pace W, Pasarica M, Phipatanakul W, Riley I, Rodriguez-Louis J, Shenoy K, Stranges P, Tapp H, Wechsler M. Maintenance of an Asthma Intervention Post-Trial: Use of a Patient-Activated Reliever-Triggered Inhaled Corticosteroid (PARTICS) Strategy in Black and Latinx Patients. The Journal Of The American Board Of Family Medicine 2025, 38: 378-382. PMID: 40578913, PMCID: PMC12616832, DOI: 10.3122/jabfm.2024.240014r2.
- Lugogo N, Peters A, Chupp G, Wechsler M, Caveney S, Martin N, Parikh B, Ambrose C. Réponses cliniques au tézépélumab chez des patients souffrant d’asthme sévère non contrôlé avec des antécédents de polypose nasosinusienne, d’après l’étude NAVIGATOR. Revue Des Maladies Respiratoires Actualités 2025, 17: 212. DOI: 10.1016/j.rmra.2024.11.445.
- Israel E, Chupp G, Lugogo N, Llanos J, Martin N, Martin N, Ambrose C, Jackson D. P23 Asthma exacerbation rates as a function of biomarker levels 4 weeks after initiation of tezepelumab treatment: an analysis of the NAVIGATOR study. 2024, a121-a122. DOI: 10.1136/thorax-2024-btsabstracts.184.
- Lugogo N, Chupp G, Corren J, Israel E, Molfino N, Martin N, Spahn J, Ambrose C. TEZEPELUMAB EFFECTS ON INFLAMMATORY BIOMARKERS IN PATIENTS WITH SEVERE, UNCONTROLLED ASTHMA BY BASELINE BIOMARKER LEVEL. Annals Of Allergy Asthma & Immunology 2024, 133: s53-s54. DOI: 10.1016/j.anai.2024.08.184.
- Zidan E, Wilson G, Shin J, Chupp G. The next frontier Defining and optimizing treatments for patients with type 2 low asthma. Annals Of Allergy Asthma & Immunology 2024, 134: 3-4. PMID: 39414022, DOI: 10.1016/j.anai.2024.10.013.
- Buchheit K, Shaw D, Chupp G, Lehtimaki L, Heffler E, Finney‐Hayward T, Zangrilli J, Kwiatek J, Siddiqui S, Roufosse F, Thamboo A, West N, Vichiendilokkul A, Hellings P, Peters A, Howarth P. Interleukin‐5 as a pleiotropic cytokine orchestrating airway type 2 inflammation: Effects on and beyond eosinophils. Allergy 2024, 79: 2662-2679. PMID: 39359069, DOI: 10.1111/all.16303.
- WECHSLER M, CHUPP G, ISRAEL E, CASTRO M, BOBER M, LINDSLEY A, SPAHN J, AMBROSE C. EFFICACY OF TEZEPELUMAB IN PATIENTS WITH SEVERE, UNCONTROLLED ASTHMA AND ALLERGIC RHINITIS GROUPED BY BASELINE BLOOD EOSINOPHIL COUNT: POOLED ANALYSIS OF PATHWAY AND NAVIGATOR. Chest 2024, 166: a4664-a4680. DOI: 10.1016/j.chest.2024.06.2821.
- Pavord I, Howarth P, Chan R, Yang S, Kolterer S, Zhang L, Chupp G. Mepolizumab in patients with asthma and features of COPD: A MENSA/MUSCA post hoc analysis. 2024, pa4492. DOI: 10.1183/13993003.congress-2024.pa4492.
- Wilson G, Gautam S, Chupp G. Does Eosinophil Heterogeneity Translate into Functional Diversity? A Review of the Evolving Paradigm of Eosinophil Heterogeneity in Asthma. Biomedicines 2024, 12: 2011. PMID: 39335525, PMCID: PMC11428232, DOI: 10.3390/biomedicines12092011.
- Zaeh S, Zimmerman Z, Eakin M, Chupp G. Adoption and implementation of maintenance and reliever therapy for adults with moderate-to-severe asthma. Annals Of Allergy Asthma & Immunology 2024, 133: 318-324. PMID: 38897404, PMCID: PMC11344662, DOI: 10.1016/j.anai.2024.06.011.
- Carr T, Moore W, Kraft M, Brusselle G, Castro M, Chupp G, Wechsler M, Hunter G, Lindsley A, Llanos J, Burke L, Chandarana S, Ambrose C. Efficacy of Tezepelumab in Patients with Severe, Uncontrolled Asthma Across Multiple Clinically Relevant Subgroups in the NAVIGATOR Study. Advances In Therapy 2024, 41: 2978-2990. PMID: 38802635, PMCID: PMC11213736, DOI: 10.1007/s12325-024-02889-8.
- Chupp G, Murphy K, Gandhi H, Gilbert I, Bleecker E. Asthma control in the United States Relationships between short-acting β2-agonist and systemic corticosteroid use. Annals Of Allergy Asthma & Immunology 2024, 133: 302-309. PMID: 38740134, DOI: 10.1016/j.anai.2024.05.003.
- Lugogo N, Peters A, Chupp G, Wechsler M, Caveney S, Martin N, Parikh B, Ambrose C. Clinical Responses to Tezepelumab in Patients With Severe, Uncontrolled Asthma, and a History of Nasal Polyps from the NAVIGATOR Study. American Journal Of Respiratory And Critical Care Medicine 2024, 209: a5251-a5251. DOI: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a5251.
- Liu M, Chaudhuri R, Chupp G, Heaney L, Lee J, Pilette C, Brusselle G, Cristancho R, Zhang L, Howarth P. Impact of Atopic Status, Prior Omalizumab Use and Baseline Blood Eosinophil Count Alone and in Combination With Total Serum IgE on Maintenance OCS Reduction Outcomes in Patients With Severe Asthma Treated With Mepolizumab in the REALITI-A Study. American Journal Of Respiratory And Critical Care Medicine 2024, 209: a5376-a5376. DOI: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a5376.
- Israel E, Chupp G, Lugogo N, Llanos J, Martin N, Martin N, Ambrose C, Jackson D. Asthma Exacerbation Rates as a Function of Biomarker Levels 4 Weeks After Initiation of Tezepelumab Treatment: An Analysis of the NAVIGATOR Study. American Journal Of Respiratory And Critical Care Medicine 2024, 209: a6704-a6704. DOI: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a6704.
- Wilson G, Liu Q, Gautam S, Knight J, Shelar A, Stewart E, Visness C, Sanders J, Gill M, Gruchalla R, Liu A, Kattan M, Hershey G, Togias A, Becker P, Altman M, Busse W, Jackson D, Montgomery R, Chupp G. Innate Immune Mechanisms Associated With Exacerbations on Mepolizumab. American Journal Of Respiratory And Critical Care Medicine 2024, 209: a6984-a6984. DOI: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a6984.
- Krishna N, Goss J, Dell L, Vazifedan T, Chupp G, Thienel U, Cunnion K. RLS-0071 Independently Inhibits Neutrophil Migration and Myeloperoxidase Activity and NETosis in Humans Challenged With LPS by Inhalation. American Journal Of Respiratory And Critical Care Medicine 2024, 209: a6690-a6690. DOI: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a6690.
- Zimmerman Z, Eakin M, Chupp G, Zaeh S. Utilization of Single Maintenance and Reliever Therapy (SMART) for Moderate and Severe Asthma. American Journal Of Respiratory And Critical Care Medicine 2024, 209: a6601-a6601. DOI: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a6601.
- Bourdin A, Chupp G, Jackson D, Cohen D, Emerath U, Shavit A, Kurdyukova Y, Menzies-Gow A. MELTEMI and COLUMBA: 5-Year Comparative Safety Analysis of Benralizumab and Mepolizumab. The Journal Of Allergy And Clinical Immunology In Practice 2024, 12: 2074-2083.e4. PMID: 38677588, DOI: 10.1016/j.jaip.2024.04.033.
- Wilson G, Knight J, Liu Q, Shelar A, Stewart E, Wang X, Yan X, Sanders J, Visness C, Gill M, Gruchalla R, Liu A, Kattan M, Khurana Hershey G, Togias A, Becker P, Altman M, Busse W, Jackson D, Montgomery R, Chupp G. Activated sputum eosinophils associated with exacerbations in children on mepolizumab. The Journal Of Allergy And Clinical Immunology 2024, 154: 297-307.e13. PMID: 38485057, PMCID: PMC11305967, DOI: 10.1016/j.jaci.2024.01.031.
- Busse W, Chupp G, Corbridge T, Stach-Klysh A, Oppenheimer J. Targeting Asthma Remission as the Next Therapeutic Step Toward Improving Disease Control. The Journal Of Allergy And Clinical Immunology In Practice 2024, 12: 894-903. PMID: 38320720, DOI: 10.1016/j.jaip.2024.01.044.
- Chupp G, Baudy P, Carstens D, North B, Danka M, Roy S, Marshall H, Merkel P. Utilizing Machine Learning with Claims Data to Diagnose and Quantify the Prevalence of Eosinophilic Granulomatosis with Polyangiitis. The Journal Of Allergy And Clinical Immunology 2024, 153: ab215. DOI: 10.1016/j.jaci.2023.11.694.
- Zaeh S, Eakin M, Chupp G. Implementing Antiinflammatory Reliever Strategies in Asthma The Evolving Paradigm of Asthma Management. Chest 2024, 165: 250-252. PMID: 38336438, DOI: 10.1016/j.chest.2023.09.004.
- Chupp G, Alobid I, Lugogo N, Kariyawasam H, Bourdin A, Chaker A, Smith S, Sousa A, Mayer B, Chan R, Matucci A, Chachuat L. Mépolizumab est associé à des bénéfices cliniques chez les patients atteints de polypose nasosinusienne, indépendamment de l’utilisation antérieure de corticostéroïdes systémiques. Revue Des Maladies Respiratoires Actualités 2024, 16: 188-189. DOI: 10.1016/j.rmra.2023.11.387.
- Brusselle G, Lougheed D, Canonica G, Munoz-Esquerre M, Heaney L, Price R, Howarth P, Raimondi A, Gardiner F, Chupp G, Welte T, Picaud C. Obtention d’une rémission clinique dans l’asthme sévère après un traitement par mépolizumab : résultats de l’étude REALITI-A à 2 ans. Revue Des Maladies Respiratoires Actualités 2024, 16: 192-193. DOI: 10.1016/j.rmra.2023.11.393.
- Gautam S, Chu J, Cohen A, Kaur R, Lee S, Wilson G, Liu Q, Gomez J, Rajaveen H, Yan X, Cohn L, Clark B, Chupp G. Sputum alarmins delineate distinct T2 cytokine pathways and unique subtypes of patients with asthma. Allergy 2023, 78: 3274-3277. PMID: 37874609, PMCID: PMC10842366, DOI: 10.1111/all.15915.
- Liu Y, Zhao J, Adams T, Wang N, Schupp J, Wu W, McDonough J, Chupp G, Kaminski N, Wang Z, Yan X. Correction: iDESC: identifying differential expression in single-cell RNA sequencing data with multiple subjects. BMC Bioinformatics 2023, 24: 394. PMID: 37858060, PMCID: PMC10588114, DOI: 10.1186/s12859-023-05523-6.
- MOORE W, LUGOGO N, CHUPP G, MARTIN N, AMBROSE C, COOK W, ACKERT J. EFFICACY OF TEZEPELUMAB IN PATIENTS WITH SEVERE, UNCONTROLLED ASTHMA WITH COMORBID GASTROESOPHAGEAL REFLUX DISEASE: A POOLED ANALYSIS OF THE PATHWAY AND NAVIGATOR STUDIES. Chest 2023, 164: a4-a7. DOI: 10.1016/j.chest.2023.07.073.
- CHUPP G, LUGOGO N, WECHSLER M, LAWSON K, LINDSLEY A, SPAHN J, AMBROSE C. LONG-TERM EFFICACY OF TEZEPELUMAB IN PATIENTS WITH SEVERE, UNCONTROLLED ASTHMA BY BASELINE BODY MASS INDEX. Chest 2023, 164: a9-a14. DOI: 10.1016/j.chest.2023.07.075.
- Oppenheimer J, Carrillo Díaz T, Martínez Moragón E, Sanchez Herrero M, Bañas Conejero D, Chupp G, Price R, Raimondi A, Zhang S, Howarth P, Domingo Ribas C. Late Breaking Abstract - Clinical remission with mepolizumab in severe asthma: impact of lung function parameters. 2023, pa646. DOI: 10.1183/13993003.congress-2023.pa646.
- iDESC: identifying differential expression in single-cell RNA sequencing data with multiple subjectsLiu Y, Zhao J, Adams T, Wang N, Schupp J, Wu W, McDonough J, Chupp G, Kaminski N, Wang Z, Yan X. iDESC: identifying differential expression in single-cell RNA sequencing data with multiple subjects. BMC Bioinformatics 2023, 24: 318. PMID: 37608264, PMCID: PMC10463720, DOI: 10.1186/s12859-023-05432-8.
- Chupp G, Alobid I, Lugogo N, Kariyawasam H, Bourdin A, Chaker A, Smith S, Sousa A, Mayer B, Chan R, Matucci A. Mepolizumab Reduces Systemic Corticosteroid Use in Chronic Rhinosinusitis With Nasal Polyps. The Journal Of Allergy And Clinical Immunology In Practice 2023, 11: 3504-3512.e2. PMID: 37586475, DOI: 10.1016/j.jaip.2023.08.015.
- Liu Y, Rajeevan H, Simonov M, Lee S, Wilson F, Desir G, Vinetz J, Yan X, Wang Z, Clark B, Possick J, Price C, Lutchmansingh D, Ortega H, Zaeh S, Gomez J, Cohn L, Gautam S, Chupp G. Differences in Mortality Among Patients With Asthma and COPD Hospitalized With COVID-19. The Journal Of Allergy And Clinical Immunology In Practice 2023, 11: 3383-3390.e3. PMID: 37454926, PMCID: PMC10787810, DOI: 10.1016/j.jaip.2023.07.006.
- Zaeh S, Chupp G, Eakin M. Is there a best strategy to prevent asthma exacerbations in inner-city patients with asthma? Annals Of Allergy Asthma & Immunology 2023, 132: 11-12. PMID: 37433383, PMCID: PMC10774450, DOI: 10.1016/j.anai.2023.07.003.
- Corren J, Menzies-Gow A, Chupp G, Israel E, Korn S, Cook B, Ambrose C, Hellqvist Å, Roseti S, Molfino N, Llanos J, Martin N, Bowen K, Griffiths J, Parnes J, Colice G. Efficacy of Tezepelumab in Severe, Uncontrolled Asthma: Pooled Analysis of the PATHWAY and NAVIGATOR Clinical Trials. American Journal Of Respiratory And Critical Care Medicine 2023, 208: 13-24. PMID: 37015033, PMCID: PMC10870853, DOI: 10.1164/rccm.202210-2005oc.
- Menzies-Gow A, Bourdin A, Chupp G, Israel E, Hellqvist Å, Hunter G, Roseti S, Ambrose C, Llanos J, Cook B, Corren J, Colice G. Effect of tezepelumab on healthcare utilization in patients with severe, uncontrolled asthma The NAVIGATOR study. Annals Of Allergy Asthma & Immunology 2023, 131: 343-348.e2. PMID: 37263380, DOI: 10.1016/j.anai.2023.05.028.
- Rabe K, Pavord I, Busse W, Chupp G, Izuhara K, Altincatal A, Gall R, Pandit‐Abid N, Deniz Y, Rowe P, Jacob‐Nara J, Radwan A. Dupilumab improves long‐term outcomes in patients with uncontrolled, moderate‐to‐severe GINA‐based type 2 asthma, irrespective of allergic status. Allergy 2023, 78: 2148-2156. PMID: 37073882, DOI: 10.1111/all.15747.
- Liu Y, Rajeevan H, Simonov M, Wilson F, Desir G, Vinetz J, Yan X, Wang Z, Clark B, Possick J, Price C, Lutchmansingh D, Gomez J, Cohn L, Gautam S, Chupp G. Mortality Differences Among Patients with Airway Disease Hospitalized with COVID-19. American Journal Of Respiratory And Critical Care Medicine 2023, 207: a6297-a6297. DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6297.
- Zaeh S, Eakin M, Chupp G. Clinical Practices and Barriers to the Use of Single Maintenance and Reliever Therapy for Asthma. American Journal Of Respiratory And Critical Care Medicine 2023, 207: a6006-a6006. DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6006.
- Wilson G, Liu Q, Knight J, Shelar A, Stewart E, Visness C, Sanders J, Gill M, Gruchalla R, Liu A, Kattan M, Hershey G, Togias A, Becker P, Altman M, Busse W, Jackson D, Montgomery R, Chupp G. Functional Analysis of Sputum Eosinophil Subpopulations in Children with Asthma. American Journal Of Respiratory And Critical Care Medicine 2023, 207: a3016-a3016. DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3016.
- Chupp G, Liu Q, Adams T, Schupp J, Wilson G, Grant N, Gomez J, Cohn L, Kaminski N, Akuthota P, Weiss S, Glass K, Bleecker E, Meyers D, Tantisira K, Yan X. Activation of Adam12-SDC4 and CCL22-CCR4 Pathways in the Airway in Asthma. American Journal Of Respiratory And Critical Care Medicine 2023, 207: a5689-a5689. DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a5689.
- Brusselle G, Lougheed M, Canonica G, Munoz-Esquerre M, Heaney L, Price R, Howarth P, Raimondi A, Gardiner F, Chupp G, Welte T. Clinical Remission Achievement in Severe Asthma Following Mepolizumab Treatment: Results from the REALITI-A Study at 2 Years. American Journal Of Respiratory And Critical Care Medicine 2023, 207: a5985-a5985. DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a5985.
- Kraft M, Chupp G, Reeh K, Lindsley A, Cook B, Hunter G, Ambrose C. Efficacy of Tezepelumab in Patients with Severe, Uncontrolled Asthma by Sex: Results from the Phase 3 Navigator Study. American Journal Of Respiratory And Critical Care Medicine 2023, 207: a4751-a4751. DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4751.
- Merkel P, Gandhi H, Genofre E, North B, Danka M, Roy S, Marshall H, Chupp G. Establishing a Diagnosis and the Prevalence of Eosinophilic Granulomatosis with Polyangiitis Through Claims Data Using Machine Learning. American Journal Of Respiratory And Critical Care Medicine 2023, 207: a4830-a4830. DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4830.
- Pavord I, Gardiner F, Heaney L, Domingo C, Price R, Pullan A, Oppenheimer J, Brusselle G, Nagase H, Chupp G, Pizzichini E, Bañas-Conejero D, Howarth P. Remission outcomes in severe eosinophilic asthma with mepolizumab therapy: Analysis of the REDES study. Frontiers In Immunology 2023, 14: 1150162. PMID: 37122713, PMCID: PMC10131245, DOI: 10.3389/fimmu.2023.1150162.
- Chupp G, Heaney L, Price R, Brusselle G, Gardiner F, Raimondi A, Chaudhuri R, Howarth P. Real-World Impact of Mepolizumab on the Oral Corticosteroid Freedom Component of Clinical Remission in Severe Eosinophilic Asthma: International, Prospective REALITI-A Study. The Journal Of Allergy And Clinical Immunology 2023, 151: ab20. DOI: 10.1016/j.jaci.2022.12.066.
- Corren J, Wechsler M, Chupp G, Roseti S, Hellqvist Å, Martin N, Llanos J, Ambrose C, Colice G. Efficacy and safety of tezepelumab in patients with uncontrolled disease while receiving maintenance therapy for moderate or severe asthma. The Journal Of Allergy And Clinical Immunology In Practice 2022, 11: 943-945.e2. PMID: 36375743, DOI: 10.1016/j.jaip.2022.10.042.
- Ortega H, Katz L, Chupp G. Asthma exacerbations during the pandemic: Time to rethink clinical markers. Journal Of Allergy And Clinical Immunology Global 2022, 2: 97-100. PMID: 36281240, PMCID: PMC9581642, DOI: 10.1016/j.jacig.2022.09.003.
- BUSSE W, CHUPP G, STANALAND M, CRAWFORD J, SLADE D. CAPTAIN: EFFECTS OF AGE AS A CONTINUOUS VARIABLE ON ASTHMA CONTROL. Chest 2022, 162: a1939-a1940. DOI: 10.1016/j.chest.2022.08.1604.
- CORREN J, WECHSLER M, CHUPP G, AMBROSE C, ROSETI S, HELLQVIST Å, ACKERT J, MARTIN N, COLICE G. EFFICACY OF TEZEPELUMAB IN PATIENTS WITH UNCONTROLLED ASTHMA DESPITE RECEIVING TREATMENT FOR MODERATE OR SEVERE DISEASE: POOLED ANALYSIS OF PATHWAY AND NAVIGATOR STUDIES. Chest 2022, 162: a21-a22. DOI: 10.1016/j.chest.2022.08.018.
- Ayala A, Yin H, Khanal S, Niu N, Nunez M, Chupp G, Laguna T, Britto C. 117 Interleukin-6 and short-palate lung and nasal epithelium clone 1 fluctuations as sex-specific markers of acute cystic fibrosis exacerbation. Journal Of Cystic Fibrosis 2022, 21: s69. DOI: 10.1016/s1569-1993(22)00808-6.
- Shlipak M, Sheshadri A, Hsu F, Chen S, Jotwani V, Tranah G, Fielding R, Liu C, Ix J, Coca S, Pahor M, Guralnik J, Leeuwenburgh C, Caudle C, Crump L, Holmes L, Leeuwenburgh J, Lu C, Miller M, Espeland M, Ambrosius W, Applegate W, Beavers D, Byington R, Cook D, Furberg C, Harvin L, Henkin L, Hepler J, Hsu F, Lovato L, Roberson W, Rushing J, Rushing S, Stowe C, Walkup M, Hire D, Rejeski W, Katula J, Brubaker P, Mihalko S, Jennings J, Hadley E, Romashkan S, Patel K, Bonds D, McDermott M, Spring B, Hauser J, Kerwin D, Domanchuk K, Graff R, Rego A, Church T, Blair S, Myers V, Monce R, Britt N, Harris M, McGucken A, Rodarte R, Millet H, Tudor-Locke C, Butitta B, Donatto S, Cocreham S, King A, Castro C, Haskell W, Stafford R, Pruitt L, Berra K, Yank V, Fielding R, Nelson M, Folta S, Phillips E, Liu C, McDavitt E, Reid K, Kirn D, Pasha E, Kim W, Beard V, Tsiroyannis E, Hau C, Manini T, Anton S, Nayfield S, Buford T, Marsiske M, Sandesara B, Knaggs J, Lorow M, Marena W, Korytov I, Morris H, Fitch M, Singletary F, Causer J, Radcliff K, Newman A, Studenski S, Goodpaster B, Glynn N, Lopez O, Nadkarni N, Williams K, Newman M, Grove G, Bonk J, Rushing J, Kost P, Ives D, Kritchevsky S, Marsh A, Brinkley T, Demons J, Sink K, Kennedy K, Shertzer-Skinner R, Wrights A, Fries R, Barr D, Gill T, Axtell R, Kashaf S, de Rekeneire N, McGloin J, Wu K, Shepard D, Fennelly B, Iannone L, Mautner R, Sweeney Barnett T, Halpin S, Brennan M, Bugaj J, Zenoni M, Mignosa B, Williamson J, Hendrie H, Rapp S, Verghese J, Woolard N, Espeland M, Jennings J, Wilson V, Pepine C, Ariet M, Handberg E, Deluca D, Hill J, Szady A, Chupp G, Flynn G, Hankinson J, Vaz Fragoso C, Groessl E, Kaplan R. Effect of Structured, Moderate Exercise on Kidney Function Decline in Sedentary Older Adults. JAMA Internal Medicine 2022, 182: 650-659. PMID: 35499834, PMCID: PMC9062767, DOI: 10.1001/jamainternmed.2022.1449.
- Korde A, Haslip M, Ahangari F, Pober J, Chupp G, Manes P, Gonzalez A, Takyar S. Endothelial Thrombopoietin Receptor Controls Eosinophil Trafficking in Asthma and Chronic Rhinosinusitis. American Journal Of Respiratory And Critical Care Medicine 2022, 205: a5684-a5684. DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5684.
- Rothenberg M, Roufosse F, Faguer S, Gleich G, Steinfeld J, Yancey S, Mavropoulou E, Kwon N, Group H, García G, Sosso A, Wehbe L, Yañez A, Blockmans D, Roufosse F, Antila M, Blanco D, Grava S, Lima M, Pez A, Faguer S, Hamidou M, Kahn J, Lefévre G, Brockow K, Kern P, Reiter A, Walz B, Welte T, Pane F, Vannucchi A, Cerino-Javier R, Gazca-Aguilar A, Hernández-Colín D, Valdéz-López H, Kupryś-Lipińska I, Musial J, Prejzner W, Mihaly E, Popov V, Zdrenghea M, Gritsaev S, Ivanov V, Tsyba N, Alonso A, Xutgla M, Fox M, Delgado R, Rivas J, Santillana G, González A, Wardlaw A, Akuthota P, Butterfield J, Chupp G, Cox J, Gleich G, Jhaveri D, Rothenberg M. Mepolizumab Reduces Hypereosinophilic Syndrome Flares Irrespective of Blood Eosinophil Count and Interleukin-5. The Journal Of Allergy And Clinical Immunology In Practice 2022, 10: 2367-2374.e3. PMID: 35568330, DOI: 10.1016/j.jaip.2022.04.037.
- Menzies-Gow A, Bourdin A, Cook W, Ambrose C, Chupp G, Kmita K, Lanos-Ackert J, Colice G. Effect of tezepelumab on exacerbation-related oral corticosteroid use in NAVIGATOR. Pneumologie 2022, 76: s12-s13. DOI: 10.1055/s-0042-1747713.
- Wilson G, Liu Q, Knight J, Visness C, Villarreal M, Gill M, Gruchalla R, Liu A, Kattan M, Hershey G, Togias A, Becker P, Altman M, Busse W, Jackson D, Montgomery R, Chupp G. Exploring the Effect of Anti-IL5 Therapy on Sputum Eosinophils in Children With Asthma. American Journal Of Respiratory And Critical Care Medicine 2022, 205: a4833-a4833. DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a4833.
- Ramirez M, Gupta A, Chupp G, Gomez J. Proteomic Characterization of Circulating Extracellular Vesicles in Adult Asthma. American Journal Of Respiratory And Critical Care Medicine 2022, 205: a3493-a3493. DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a3493.
- Jung E, Howell R, Cohen A, Tsang D, Chupp G, Dela Cruz C, Gautam S, Brewster R, Flint J, Yin H, Ristic N, Cosme C. Chemoattractant-Receptor Homologous Molecule on Th2 Cells (CRTH2) Regulates Neutrophilic Inflammation in the Lung. American Journal Of Respiratory And Critical Care Medicine 2022, 205: a2534-a2534. DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2534.
- Cao G, Lam H, Jude J, Karmacharya N, Kan M, Jester W, Koziol-White C, Himes B, Chupp G, An S, Panettieri R. Inhibition of ABCC1 Decreases cAMP Egress and Promotes Human Airway Smooth Muscle Cell Relaxation. American Journal Of Respiratory And Critical Care Medicine 2022, 205: a3280-a3280. DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a3280.
- Chupp G, Lee J, Liu M, Schleich F, Heaney L, Ribas C, Carrillo-Díaz T, Aparicio M, Moragón E, Sanchez-Herrero M, Gardiner F, Alfonso-Cristancho R, Jakes R, Price R, Howarth P. Mepolizumab Demonstrates Real-world Clinical Effectiveness in both Type 2 Biomarker High and Type 2 Biomarker Low Patients with Severe Asthma. The Journal Of Allergy And Clinical Immunology 2022, 149: ab318. DOI: 10.1016/j.jaci.2021.12.019.
- Chupp G, Alobid I, Lugogo N, Kariyawasam H, Bourdin A, Chaker A, Sousa A, Martin N, Yang S, Mayer B, Chan R, Matucci A, Chachuat L. Le mépolizumab réduit l’utilisation de corticostéroïdes systémiques chez les patients atteints de rhinosinusite chronique avec polypes nasaux. Revue Des Maladies Respiratoires Actualités 2022, 14: 34-35. DOI: 10.1016/j.rmra.2021.11.508.
- Steinfeld J, Gleich G, Roufosse F, Chupp G, Faguer S, Reiter A, Walz B, Bentley J, Bradford E, Yancey S, Picaud C. Tolérance et efficacité de mépolizumab dans le syndrome hyperéosinophilique : une étude d’extension en ouvert. La Revue De Médecine Interne 2021, 42: a411. DOI: 10.1016/j.revmed.2021.10.126.
- Oppenheimer J, Abott C, Chang S, Chupp G, Crawford J, Mannino D, Win P. D010 CAPTAIN STUDY: EFFECTS OF BASELINE IGE LEVELS ON TRIPLE THERAPY RESPONSE IN INADEQUATELY CONTROLLED ASTHMA. Annals Of Allergy Asthma & Immunology 2021, 127: s14. DOI: 10.1016/j.anai.2021.08.048.
- Israel E, Chupp G, Colice G, Cook B, Ambrose C, Roseti S, Hellqvist Å, Llanos-Ackert J. D011 TEZEPELUMAB EFFICACY ACCORDING TO US OMALIZUMAB ELIGIBILITY: RESULTS FROM THE NAVIGATOR PHASE 3 STUDY. Annals Of Allergy Asthma & Immunology 2021, 127: s14-s15. DOI: 10.1016/j.anai.2021.08.049.
- Chupp G, Menzies-Gow A, Ambrose C, Cook W, Kmita K, Lindsley A, Llanos-Ackert J, Colice G, Lugogo N. EFFICACY OF TEZEPELUMAB IN PATIENTS WITH SEVERE, UNCONTROLLED ASTHMA GROUPED BY BASELINE BMI IN THE NAVIGATOR STUDY. Chest 2021, 160: a37-a40. DOI: 10.1016/j.chest.2021.07.078.
- Chupp G, Feigler N, Gandhi H. VARIATIONS HIGHLIGHTED IN HYPERLOCAL HEATMAPS CAN ADDRESS UNMET NEED AND ALLOCATION OF RESOURCES IN COPD. Chest 2021, 160: a1796-a1797. DOI: 10.1016/j.chest.2021.07.1630.
- Kerstjens H, Abbott C, Boulet L, Chang S, Chupp G, Crawford J, Hanania N, Nathan R, Oppenheimer J, Pizzichini E, Sagara H, Busse W. CAPTAIN: Effects of triple therapy on FEV1 response in patients with inadequately controlled asthma on ICS/LABA. 2021, pa3386. DOI: 10.1183/13993003.congress-2021.pa3386.
- Israel E, Menzies-Gow A, Chupp G, Ambrose C, Cook B, Hunter G, Llanos-Ackert J, Downie J, Colice G. Efficacy of tezepelumab in adolescents with severe, uncontrolled asthma. 2021, oa1490. DOI: 10.1183/13993003.congress-2021.oa1490.
- Bourdin A, Menzies-Gow A, Chupp G, Ambrose C, Kmita K, Llanos-Ackert J, Colice G, Cook B. Effect of tezepelumab on exacerbation-related oral corticosteroid use in NAVIGATOR. 2021, oa1484. DOI: 10.1183/13993003.congress-2021.oa1484.
- Korn S, Bourdin A, Chupp G, Colice G, Ambrose C, Kmita K, Llanos-Ackert J, Molfino N, Cook B. Effect of tezepelumab on the proportion of exacerbation-free patients with severe, uncontrolled asthma in NAVIGATOR. 2021, oa1198. DOI: 10.1183/13993003.congress-2021.oa1198.
- Kay S, Chupp G, Gomez J. Sex-Specific Gene Expression in the Sputum of Patients with Asthma. American Journal Of Respiratory And Critical Care Medicine 2021, 203: a1383-a1383. DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1383.
- Chaudhuri R, Caruso C, Chupp G, Fera T, Koehler T, Schleich F, Valero A, Yang S, Howarth P, Jakes R, Maxwell A, Price R, Cristancho R. International Differences in the Use of Mepolizumab to Treat Severe Asthma – Impact of Reimbursement Policies. American Journal Of Respiratory And Critical Care Medicine 2021, 203: a1595-a1595. DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1595.
- Steinfeld J, Gleich G, Roufosse F, Chupp G, Faguer S, Reiter A, Walz B, Bentley J, Bradford E, Yancey S. Safety and Efficacy of Mepolizumab in Hypereosinophilic Syndrome: an Open-Label Extension Study. American Journal Of Respiratory And Critical Care Medicine 2021, 203: a1351-a1351. DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1351.
- Chupp G, Alobid I, Lugogo N, Kariyawasam H, Bourdin A, Chaker A, Sousa A, Martin N, Yang S, Mayer B, Chan R, Matucci A. Mepolizumab Reduces Systemic Corticosteroid Use in Patients with Chronic Rhinosinusitis with Nasal Polyps. American Journal Of Respiratory And Critical Care Medicine 2021, 203: a1344-a1344. DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1344.
- Bourdin A, Korn S, Chupp G, Cosio B, Arbetter D, Shah M, Gil E. Integrated Safety and Efficacy Among Patients with Severe Asthma Receiving Benralizumab for Up to Five Years. American Journal Of Respiratory And Critical Care Medicine 2021, 203: a1205-a1205. DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1205.
- Bourdin A, Menzies-Gow A, Chupp G, Israel E, Hellqvist, Hunter G, Ambrose C, Ackert J, Colice G, Cook B, Corren J. Reductions in Asthma Exacerbation-Related Hospitalizations and Emergency Department Visits in Patients with Severe, Uncontrolled Asthma Treated with Tezepelumab: Results from the Phase 3 NAVIGATOR Study. American Journal Of Respiratory And Critical Care Medicine 2021, 203: a1203-a1203. DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1203.
- Chupp G, Beeh K, Jauhiainen A, Necander S, Brown M, Hamrén U, Forsman H, Kurdyukova Y, Steele J, Astbury C, Psallidas I. Results of a Phase 2b Dose Finding Study of Velsecorat, an Inhaled Non-Steroidal, Selective Glucocorticoid Receptor Modulator in Asthma (GRANIT). American Journal Of Respiratory And Critical Care Medicine 2021, 203: a1202-a1202. DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1202.
- Corren J, Bourdin A, Chupp G, Israel E, Ambrose C, Ackert J, Kmita K, Cook B, Colice G, Menzies-Gow A. Efficacy of Tezepelumab in Patients with Severe, Uncontrolled Asthma Grouped by Baseline Blood Eosinophil Count and Fractional Exhaled Nitric Oxide Level: Results from the NAVIGATOR Phase 3 Study. American Journal Of Respiratory And Critical Care Medicine 2021, 203: a1198-a1198. DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1198.
- Menzies-Gow A, Corren J, Bourdin A, Chupp G, Israel E, Griffiths J, Hellqvist Å, Bowen K, Kaur P, Almqvist G, Ponnarambil S, Colice G. Efficacy and Safety of Tezepelumab in Adults and Adolescents with Severe, Uncontrolled Asthma: Results from the Phase 3 NAVIGATOR Study. The Journal Of Allergy And Clinical Immunology 2021, 147: ab249. DOI: 10.1016/j.jaci.2020.12.050.
- Chupp G, Kline J, Khatri S, McEvoy C, Shifren A, Bansal S, McClelland M, Dransfield M, Olivenstein R, Lawson E, Simoff M, Wahidi M, Lamb C, Ferguson J, Haas A, Hogarth D, Tejedor R, Laviolette M. LONG-TERM EFFICACY AND SAFETY OF BRONCHIAL THERMOPLASTY: 5-YEAR FOLLOW-UP RESULTS FROM A LARGE-SCALE PROSPECTIVE STUDY. Chest 2020, 158: a12-a16. DOI: 10.1016/j.chest.2020.08.059.
- Bleecker E, Murphy K, Gandhi H, Gilbert I, Zein J, Reibman J, Chupp G. Natural history of disease burden for US patients with asthma vs asthma and COPD. 2020, 1397. DOI: 10.1183/13993003.congress-2020.1397.
- Murphy K, Chipps B, Beuther D, Wise R, McCann W, Gilbert I, Eudicone J, Gandhi H, Harding G, Coyne K, Zeiger R, Board P, Kobernick A, Mohammad A, Cherry A, Fein A, Gaines A, Ramsey A, Michaud A, Palmer A, Kim A, Smith A, White A, Ricci A, Kettelhut B, Modena B, Stone B, Rolston B, Schnapf B, Krajicek B, Kraft C, Hopkins C, Natalie C, Anderson C, Czajkowski C, Arce D, Hamlin D, Hill D, Mares D, Pham D, Liao D, Simmons D, Johnson D, Jhaveri D, Maselli D, Kerwin E, Schuman E, Sher E, Bleecker E, Rakowski E, Hsu F, Averill F, Barsanti F, Gross G, Chupp G, Head G, Nasir H, Lee H, Barjaktarevic I, Cook J, Krainson J, Pearl J, Bellak J, Perez-Fernandez J, Rehm J, Trevor J, Most J, Hanson J, Blessing-Moore J, Biller J, Gedell J, Southard J, Chancellor J, Ilowite J, Romeo J, Mercado J, Fisher J, Greiwe J, Gregory K, Nadeau K, Shenoy K, Tan L, Stefanowicz L, Humes L, Bowers L, O’Connor M, Perez M, White M, Hegewald M, Wilson M, Sikora M, Morganroth M, Smith M, Farooqui N, Lesch N, Jain N, Parikh N, Hartog N, Luthin P, Stewart P, O’Connor P, Schochet P, Goldberg P, Patel P, Chinthrajah R, Sidhu R, Ayinla R, Brown R, Stadtler R, Wachs R, Balkissoon R, Duplantier R, Puente R, Settipane R, Mustafa S, Surani S, Jawad S, Adams S, Villegas S, Al-Farra S, Subramanian S, Bains S, Kelsen S, Wise S, Estrella-Eades S, Smith S, Qureshi T, Chen T, Kelbel T, Miller T, Jain V, Soong W, Soler X, Mattar Z. Development of the Asthma Impairment and Risk Questionnaire (AIRQ): A Composite Control Measure. The Journal Of Allergy And Clinical Immunology In Practice 2020, 8: 2263-2274.e5. PMID: 32387166, DOI: 10.1016/j.jaip.2020.02.042.
- Wang Z, Shan N, Yan X, Mane S, Gomez J, Chupp G. Whole Exome Sequencing of Severe Asthma Identifies Novel Gene Association Candidates. 2020, a1336-a1336. DOI: 10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a1336.
- Bleecker E, Murphy K, Gandhi H, Gilbert I, Chupp G. Assessing Asthma Control in the United States by Examining the Relationships Between Short-Acting Beta 2 -Agonist and Systemic Corticosteroid Use. 2020, a1818-a1818. DOI: 10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a1818.
- Koziol-White C, Parikh V, Chupp G, Panettieri R. Blocking YKL-40 (Chitinase-Like Protein Chitinase 3) Reverses IL-13/IL-4-Induced Hyporesponsiveness to Bronchodilators in Human Small Airways and in Human Airway Smooth Muscle Cells. 2020, a1252-a1252. DOI: 10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a1252.
- Glynn N, Gmelin T, Santanasto A, Lovato L, Lange‐Maia B, Nicklas B, Fielding R, Manini T, Myers V, Rekeneire N, Spring B, Pahor M, King A, Rejeski W, Newman A, Pahor M, Guralnik J, Anton S, Buford T, Leeuwenburgh C, Nayfield S, Manini T, Caudle C, Crump L, Holmes L, Lee J, Lu C, Miller M, Espeland M, Ambrosius W, Applegate W, Beavers D, Byington R, Cook D, Furberg C, Harvin L, Henkin L, Hepler J, Hsu F, Joyce K, Lovato L, Pierce J, Roberson W, Robertson J, Rushing J, Rushing S, Stowe C, Walkup M, Hire D, Rejeski W, Katula J, Brubaker P, Mihalko S, Jennings J, Chen S, Pierce J, Chen H, Hadley E, Romashkan S, Patel K, Bethesda, Bonds D, McDermott M, Spring B, Hauser J, Kerwin D, Domanchuk K, Graff R, Rego A, Church T, Blair S, Myers V, Monce R, Britt N, Harris M, McGucken A, Rodarte R, Millet H, Tudor‐Locke C, Butitta B, Donatto S, Cocreham S, King A, Castro C, Haskell W, Stafford R, Pruitt L, Yank V, Berra K, Bell C, Thiessen R, Youngman K, Virgen S, Maldonado E, Tarin K, Klaftenegger H, Prosak C, Campero I, Garcia D, Soto J, Chio L, Hoskins D, Fielding R, Nelson M, Folta S, Phillips E, Liu C, McDavitt E, Reid K, Kirn D, Pasha E, Kim W, Krol J, Beard V, Tsiroyannis E, Hau C, Manini T, Pahor M, Anton S, Buford T, Marsiske M, Nayfield S, Sandesara B, Black M, Burk W, Hoover B, Knaggs J, Marena W, Korytov I, Curtis S, Lorow M, Goswami C, Lewis M, Kamen M, Bitz J, Stanton B, Hicks T, Gay C, Xie C, Morris H, Singletary F, Causer J, Yonce S, Radcliff K, Smith M, Scott J, Rodriguez M, Fitch M, Dunn M, Schllesinger J, Newman A, Studenski S, Goodpaster B, Lopez O, Glynn N, Nadkarni N, Ives D, Newman M, Grove G, Williams K, Bonk J, Rush J, Kost P, Vincent P, Gerger A, Romeo J, Monheim L, Kritchevsky S, Marsh A, Brinkley T, Demons J, Sink K, Kennedy K, Shertzer‐Skinner R, Wrights A, Fries R, Barr D, Gill T, Axtell R, Kashaf S, Rekeneire N, McGloin J, Mautner R, Huie‐White S, Bianco L, Zocher J, Wu K, Shepard D, Fennelly B, Castro R, Halpin S, Brennan M, Barnett T, Iannone L, Zenoni M, Bugaj J, Bailey C, Charpentier P, Hawthorne‐Jones G, Mignosa B, Lewis L, Williamson J, Sink K, Hendrie H, Rapp S, Verghese J, Woolard N, Espeland M, Jennings J, Wilson V, Pepine C, Ariet M, Handberg E, Deluca D, Hill J, Szady A, Chupp G, Flynn G, Gill T, Hankinson J, Vaz Fragoso C, Groessl E, Kaplan R. Impact of Baseline Fatigue on a Physical Activity Intervention to Prevent Mobility Disability. Journal Of The American Geriatrics Society 2019, 68: 619-624. PMID: 31867713, PMCID: PMC8061638, DOI: 10.1111/jgs.16274.
- Mohan A, Grace J, Mainardi A, Chupp G, Lugogo N. Biomarkers, Targeted Therapies, Biologics, and Bronchial Thermoplasty. Respiratory Medicine 2019, 123-153. DOI: 10.1007/978-3-030-20812-7_8.
- Amick A, Liu Q, Gautam S, Chupp G, Dela Cruz C, Sharma L. Measurement of Chitinase Activity in Biological Samples. Journal Of Visualized Experiments 2019 DOI: 10.3791/60159-v.
- Stewart E, Chupp G, Montgomery R, Liu Q, Estrom J. Analysis of Sputum Immune Cell Populations and Their Functional Status in Asthmatics. 2019, a2916-a2916. DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2916.
- Gomez J, Chen A, Yan X, Cohn L, Chupp G. MicroRNA miR-223 Is Associated with Lung Function Impairment and TH17 Inflammation in Asthma. 2019, a2929-a2929. DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2929.
- Yan X, Liu Q, Mihaljinec A, Gomez J, Cohn L, Chupp G. Cell Lineage Defined by Single Cell Transcriptomics of the Sputum in Asthma. 2019, a6085-a6085. DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a6085.
- Chu J, Yan X, Liang A, Hu B, Gomez J, Chupp G. Integration of Sputum eQTL and GWAS Indicates IL-27/EBI3 Pathway Is Associated with Severe Asthma. 2019, a6088-a6088. DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a6088.
- Bleecker E, Murphy K, Gandhi H, Gilbert I, Chupp G. The Natural History of the Burden of Asthma in the United States by Age and Sex. 2019, a7397-a7397. DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7397.
- Chupp G, Kline J, Khatri S, McEvoy C, Silvestri G, Shifren A, Castro M, Bansal S, McClelland M, Dransfield M, Olivenstein R, Kahlstrom R, Ryan S, Lawson E, Simoff M, Wahidi M, Lamb C, Ferguson J, Haas A, Hogarth D, Tejedor R, Toth J, Majid A, Fitzgerald J, Enfield K, Grubb G, Laviolette M. Long-Term Efficacy and Safety of Bronchial Thermoplasty (BT): 4 Year Follow-Up Results from a Large Scale Prospective Study. 2019, a2683-a2683. DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2683.
- Chupp G, Brown M, Beeh K, Wahlby-Hamren U, Ekelund A, Barkstedt E, Forsman H, Björnsson E, Jauhiainen A, Steele J, Psallidas I. Design of a Phase 2b Dose Finding Study of AZD7594, an Inhaled Non-Steroidal, Selective Glucocorticoid Receptor Modulator, for the Treatment of Asthma. 2019, a1315-a1315. DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1315.
- Rapid onset of effect of benralizumab on morning peak expiratory flow in severe, uncontrolled asthmaChupp G, Lugogo N, Kline J, Ferguson G, Hirsch I, Goldman M, Zangrilli J, Trudo F. Rapid onset of effect of benralizumab on morning peak expiratory flow in severe, uncontrolled asthma. Annals Of Allergy Asthma & Immunology 2019, 122: 478-485. PMID: 30802500, DOI: 10.1016/j.anai.2019.02.016.
- Busse W, Chupp G, Nagase H, Albers F, Doyle S, Shen Q, Bratton D, Gunsoy N. Anti–IL-5 treatments in patients with severe asthma by blood eosinophil thresholds: Indirect treatment comparison. The Journal Of Allergy And Clinical Immunology 2018, 143: 190-200.e20. PMID: 30205189, DOI: 10.1016/j.jaci.2018.08.031.
- Chupp G, Ferguson G, Hirsch I, Goldman M, Zangrilli J, Trudo F. Benralizumab Treatment Produces Rapid Changes in Morning Peak Expiratory Flow in Patients With Severe, Uncontrolled Eosinophilic Asthma. The Journal Of Allergy And Clinical Immunology 2018, 141: ab15. DOI: 10.1016/j.jaci.2017.12.046.
- Corbett DB, Rejeski WJ, Tudor-Locke C, Glynn NW, Kritchevsky SB, McDermott MM, Church TS, Fielding RA, Gill TM, King AC, Miller ME, Chen H, Pahor M, Manini TM, Pahor M, Guralnik J, Leeuwenburgh C, Caudle C, Crump L, Holmes L, Lee J, Lu C, Salem W, Miller M, Espeland M, Ambrosius W, Applegate W, Beavers D, Byington R, Cook D, Furberg C, Harvin L, Henkin L, Hepler J, Hsu F, Lovato L, Roberson W, Rushing J, Rushing S, Stowe C, Walkup M, Hire D, Rejeski W, Katula J, Brubaker P, Mihalko S, Jennings J, Hadley E, Romashkan S, Patel K, Bonds D, McDermott M, Hauser J, Kerwin D, Domanchuk K, Graff R, Rego A, Church T, Blair S, Myers V, Monce R, Britt N, Harris M, McGucken A, Rodarte R, Millet H, Tudor-Locke C, Butitta B, Donatto S, Cocreham S, King A, Castro C, Haskell W, Stafford R, Pruitt L, Berra K, Yank V, Fielding R, Nelson M, Folta S, Phillips E, Liu C, McDavitt E, Reid K, Kim W, Beard V, Manini T, Pahor M, Anton S, Buford T, Marsiske M, Sandesara B, Knaggs J, Lorow M, Marena W, Korytov I, Morris H, Fitch M, Singletary F, Causer J, Radcliff K, Newman A, Studenski S, Goodpaster B, Glynn N, Lopez O, Nadkarni N, Williams K, Newman M, Grove G, Bonk J, Rush J, Kost P, Ives D, Kritchevsky S, Marsh A, Brinkley T, Demons J, Sink K, Kennedy K, Shertzer-Skinner R, Wrights A, Fries R, Barr D, Gill T, Axtell R, Kashaf S, de Rekeneire N, McGloin J, Wu K, Shepard D, Fennelly B, Iannone L, Mautner R, Barnett T, Halpin S, Brennan M, Bugaj J, Zenoni M, Mignosa B, Williamson J, Sink K, Hendrie H, Rapp S, Verghese J, Woolard N, Espeland M, Jennings J, Pepine C, Ariet M, Handberg E, Deluca D, Hill J, Szady A, Chupp G, Flynn G, Gill T, Hankinson J, Fragoso C, Groessl E, Kaplan R. Social Participation Modifies the Effect of a Structured Physical Activity Program on Major Mobility Disability Among Older Adults: Results From the LIFE Study. The Journals Of Gerontology Series B 2017, 73: 1501-1513. PMID: 28482106, PMCID: PMC6178963, DOI: 10.1093/geronb/gbx051.
- Trevor J, Bradford E, Albers F, Bratton D, Wang-Jairaj J, Nelsen L, Chupp G, Magnan A, Brinke A. Mepolizumab Improves Lung Function and Exacerbation Rates in Severe Eosinophilic Asthma: The Musca Study - a Phase IIIb Randomized, Placebo-Controlled Tria. The Journal Of Allergy And Clinical Immunology 2017, 139: ab380. DOI: 10.1016/j.jaci.2016.12.912.
- Chupp G, Bradford E, Albers F, Bratton D, Wang-Jairaj J, Nelsen L, Trevor J, Magnan A, Brinke A. Mepolizumab Significantly Improves Health Status and Asthma Control in Severe Eosinophilic Asthma: The Musca Study - a Phase IIIb Randomized, Placebo-Controlled Trial. The Journal Of Allergy And Clinical Immunology 2017, 139: ab380. DOI: 10.1016/j.jaci.2016.12.911.
- Yao Y, Welp T, Liu Q, Niu N, Wang X, Britto CJ, Krishnaswamy S, Chupp G, Montgomery RR. Multiparameter Single Cell Profiling of Airway Inflammatory Cells. Cytometry Part B Clinical Cytometry 2017, 92: 12-20. PMID: 27807928, PMCID: PMC5250532, DOI: 10.1002/cyto.b.21491.
- Silkoff P, Laviolette M, Singh D, FitzGerald J, Kelsen S, Backer V, Porsbjerg C, Girodet P, Berger P, Kline J, Chupp G, Susulic V, Barnathan E, Baribaud F, Loza M, investigators A, Strambu I, Lam S, Eich A, Ludwig-Sengpiel A, Leigh R, Dransfield M, Calhoun W, Hussaini A, Chanez P. Identification of airway mucosal type 2 inflammation by using clinical biomarkers in asthmatic patients. The Journal Of Allergy And Clinical Immunology 2017, 140: 710-719. PMID: 28089872, DOI: 10.1016/j.jaci.2016.11.038.
- Aubertin-Leheudre M, Anton S, Beavers D, Manini T, Fielding R, Newman A, Church T, Kritchevsky S, Conroy D, McDermott M, Botoseneanu A, Hauser M, Pahor M, Gill T, Fragoso C, Fielding R, Hauser M, Pahor M, Guralnik J, Leeuwenburgh C, Caudle C, Crump L, Holmes L, Lee J, Lu C, Miller M, Espeland M, Ambrosius W, Applegate W, Beavers D, Byington R, Cook D, Furberg C, Harvin L, Henkin L, Hepler M, Hsu F, Lovato L, Roberson W, Rushing J, Rushing S, Stowe C, Walkup M, Hire D, Rejeski W, Katula J, Brubaker P, Mihalko S, Jennings J, Hadley E, Romashkan S, Patel K, Bonds D, McDermott M, Spring B, Hauser J, Kerwin D, Domanchuk K, Graff R, Rego A, Church T, Blair S, Myers V, Monce R, Britt N, Harris M, McGucken A, Rodarte R, Millet H, Tudor-Locke C, Butitta B, Donatto S, Cocreham S, King A, Castro C, Haskell W, Stafford R, Pruitt L, Berra K, Yank V, Fielding R, Nelson M, Folta S, Phillips E, Liu C, McDavitt E, Reid K, Kirn D, Pasha E, Kim W, Beard V, Tsiroyannis E, Hau C, Manini T, Pahor M, Anton S, Nayfield S, Buford T, Marsiske M, Sandesara B, Knaggs J, Lorow M, Marena W, Korytov I, Morris H, Fitch M, Singletary F, Causer J, Radcliff K, Newman A, Studenski S, Goodpaster B, Glynn N, Lopez O, Nadkarni N, Williams K, Newman M, Grove G, Bonk J, Rush J, Kost P, Ives D, Kritchevsky S, Marsh A, Brinkley T, Demons J, Sink K, Kennedy K, Shertzer-Skinner R, Wrights A, Fries R, Barr D, Gill T, Axtell R, Kashaf S, de Rekeneire N, McGloin J, Wu K, Shepard D, Fennelly B, Iannone L, Mautner R, Barnett T, Halpin S, Brennan M, Bugaj J, Zenoni M, Mignosa B, Williamson J, Sink K, Hendrie H, Rapp S, Verghese J, Woolard N, Espeland M, Jennings J, Wilson V, Pepine C, Ariet M, Handberg E, Deluca D, Hill J, Szady A, Chupp G, Flynn G, Gill T, Hankinson J, Fragoso C, Groessl E, Kaplan R. Dynapenia and Metabolic Health in Obese and Nonobese Adults Aged 70 Years and Older: The LIFE Study. Journal Of The American Medical Directors Association 2016, 18: 312-319. PMID: 27914851, PMCID: PMC5366275, DOI: 10.1016/j.jamda.2016.10.001.
- Baldassarri S, Chupp G, Leone F, Warren G, Toll B. Chest Health-care Provider Perceptions of Electronic Cigarettes. Chest 2016, 150: 1302a. DOI: 10.1016/j.chest.2016.08.1417.
- Chupp G, Yan X, Nezgovorova V, Grant N, Bradford W, Brophy C, Cohn L. MAPKAP kinase 2(MK2) expression is associated with severe asthma. 2016, pa4649. DOI: 10.1183/13993003.congress-2016.pa4649.
- Gueble M, Holm C, Grant N, Ravage-Mass L, Levesh T, Estrom J, Kapagiannidou E, Liu Q, O'Connor P, Gomez-Villalobos J, Cohn L, Chupp G. Proinflammatory cytokines and IP-10 differentiate neutrophilic and eosinophilic asthma subgroups. 2016, pa908. DOI: 10.1183/13993003.congress-2016.pa908.
- Layne AS, Hsu FC, Blair SN, Chen SH, Dungan J, Fielding RA, Glynn NW, Hajduk AM, King AC, Manini TM, Marsh AP, Pahor M, Pellegrini CA, Buford TW, Investigators L, Pahor M, Guralnik J, Leeuwenburgh C, Caudle C, Crump L, Holmes L, Lee J, Lu C, Miller M, Espeland M, Ambrosius W, Applegate W, Beavers D, Byington R, Cook D, Furberg C, Harvin L, Henkin L, Hepler J, Hsu F, Lovato L, Roberson W, Rushing J, Rushing S, Stowe C, Walkup M, Hire D, Rejeski W, Katula J, Brubaker P, Mihalko S, Jennings J, Hadley E, Romashkan S, Patel K, Bonds D, McDermott M, Spring B, Hauser J, Kerwin D, Domanchuk K, Graff R, Rego A, Church T, Blair S, Myers V, Monce R, Britt N, Harris M, McGucken A, Rodarte R, Millet H, Tudor-Locke C, Butitta B, Donatto S, Cocreham S, King A, Castro C, Haskell W, Stafford R, Pruitt L, Berra K, Yank V, Fielding R, Nelson M, Folta S, Phillips E, Liu C, McDavitt E, Reid K, Kim W, Beard V, Manini T, Pahor M, Anton S, Nayfield S, Buford T, Marsiske M, Sandesara B, Knaggs J, Lorow M, Marena W, Korytov I, Morris H, Fitch M, Singletary F, Causer J, Radcliff K, Newman A, Studenski S, Goodpaster B, Glynn N, Lopez O, Nadkarni N, Williams K, Newman M, Grove G, Bonk J, Rush J, Kost P, Ives D, Kritchevsky S, Marsh A, Brinkley T, Demons J, Sink K, Kennedy K, Shertzer-Skinner R, Wrights A, Fries R, Barr D, Gill T, Axtell R, Kashaf S, de Rekeneire N, McGloin J, Wu K, Shepard D, Fennelly B, Iannone L, Mautner R, Barnett T, Halpin S, Brennan M, Bugaj J, Zenoni M, Mignosa B, Williamson J, Sink K, Hendrie H, Rapp S, Verghese J, Woolard N, Espeland M, Jennings J, Pepine C, Ariet M, Handberg E, Deluca D, Hill J, Szady A, Chupp G, Flynn G, Gill T, Hankinson J, Fragoso C, Groessl E, Kaplan R. Predictors of Change in Physical Function in Older Adults in Response to Long-Term, Structured Physical Activity: The LIFE Study. Archives Of Physical Medicine And Rehabilitation 2016, 98: 11-24.e3. PMID: 27568165, PMCID: PMC5183463, DOI: 10.1016/j.apmr.2016.07.019.
- Baker M, Steinke J, Borish L, Chupp G. Leukotriene C4 Synthase Expression in Sputum Correlates with Disease Severity Amongst Patients with Different Clinical Phenotypes of Asthma. The Journal Of Allergy And Clinical Immunology 2016, 137: ab207. DOI: 10.1016/j.jaci.2015.12.1118.
- Ortega H, Chupp G, Bardin P, Bourdin A, Garcia G, Hartley B, Yancey S, Humbert M. The role of mepolizumab in atopic and nonatopic severe asthma with persistent eosinophilia. European Respiratory Journal 2014, 44: 239-241. PMID: 24659543, DOI: 10.1183/09031936.00220413.
- Baldassarri S, Chupp G. A 43-Year-Old Man With Intravenous Drug Abuse and Recurrent Endocarditis. Chest 2013, 144: 296a-296b. DOI: 10.1378/chest.1676394.
- Loza M, Strambu I, Laviolette M, Singh D, Fitzgerald J, Kelsen S, Eich A, Ludwig-Sengpiel A, Chupp G, Porsbjerg C, Berger P, Leigh R, Kline J, Dransfield M, Calhoun W, Hussaini A, Chanez P, Susulic V, Silkoff P, Baribaud F. ADEPT, airway disease endotyping for personalized treatment: Interim analysis of asthma patients. European Respiratory Journal 2013, 42: p748. DOI: 10.1183/13993003/erj.42.suppl_57.p748.
- Scatena R, Holm C, He S, Wright P, Sessa W, Cohn L, Gomez-Villalobos J, Mitchell A, Chupp G. Characterization Of The Poor Emotional Function Phenotype In Asthma. 2012, a3967-a3967. DOI: 10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a3967.
- Fielding RA, Rejeski WJ, Blair S, Church T, Espeland MA, Gill TM, Guralnik JM, Hsu FC, Katula J, King AC, Kritchevsky SB, McDermott MM, Miller ME, Nayfield S, Newman AB, Williamson JD, Bonds D, Romashkan S, Hadley E, Pahor M. The Lifestyle Interventions and Independence for Elders Study: Design and Methods. The Journals Of Gerontology Series A 2011, 66A: 1226-1237. PMID: 21825283, PMCID: PMC3193523, DOI: 10.1093/gerona/glr123.
- Pathways Activated during Human Asthma Exacerbation as Revealed by Gene Expression Patterns in BloodBjornsdottir US, Holgate ST, Reddy PS, Hill AA, McKee CM, Csimma CI, Weaver AA, Legault HM, Small CG, Ramsey RC, Ellis DK, Burke CM, Thompson PJ, Howarth PH, Wardlaw AJ, Bardin PG, Bernstein DI, Irving LB, Chupp GL, Bensch GW, Bensch GW, Stahlman JE, Karetzky M, Baker JW, Miller RL, Goodman BH, Raible DG, Goldman SJ, Miller DK, Ryan JL, Dorner AJ, Immermann FW, O'Toole M. Pathways Activated during Human Asthma Exacerbation as Revealed by Gene Expression Patterns in Blood. PLOS ONE 2011, 6: e21902. PMID: 21779351, PMCID: PMC3136489, DOI: 10.1371/journal.pone.0021902.
- Ramaprakash H, Shibata T, Duffy KE, Ismailoglu UB, Bredernitz RM, Moreira AP, Coelho AL, Das AM, Fursov N, Chupp GL, Hogaboam CM. Targeting ST2L Potentiates CpG-Mediated Therapeutic Effects in a Chronic Fungal Asthma Model. American Journal Of Pathology 2011, 179: 104-115. PMID: 21640974, PMCID: PMC3123853, DOI: 10.1016/j.ajpath.2011.03.032.
- Gomez J, Perez M, Mitchell A, Holm C, He S, Chupp G. Airway Macrophage Expression Signatures Associated With Severe Airflow Obstruction In Asthma. 2011, a4540-a4540. DOI: 10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a4540.
- Scatena R, Chupp G, Perez M, Gomez J, Wright P, Sessa W, Holm C. The Role Of Neurite Outgrowth Inhibitory Protein-B In Poorly Controlled Asthma. 2011, a1349-a1349. DOI: 10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a1349.
- Perez M, Gomez J, He S, Holm C, Chupp G. Characterization Of Chitinase Activity In Patients With Stable Asthma. 2011, a4334-a4334. DOI: 10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a4334.
- Ong P, Wisnewski A, Stowe M, Holm C, He X, Zheng W, Zhang C, Zhao H, Redlich C, Chupp G. The 24-bp CHIT1 Exon 10 Polymorphism Is Associated With Airway Hyperresponsiveness In A Population Of Autobody Shop Workers. 2010, a4002-a4002. DOI: 10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a4002.
- Gomez J, Perez M, He X, Mitchell A, Holm C, Chupp G. Characterization Of Chitinase Activity And YKL-40 Expression In Induced Sputum From Asthmatics: Correlations With Inflammation And Cell Viability And Gene Expression. 2010, a4279-a4279. DOI: 10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a4279.
- Perez M, Gomez J, He X, Mitchell A, Kelly E, Jarjour N, Chupp G. Correlations Between The Chitinase-Like Protein YKL-40 And IL-18 After Segmental Antigen Challenge. 2010, a5605-a5605. DOI: 10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a5605.
- Marshall P, Possick J, Chupp G. Intensive Care Unit Management of Status Asthmaticus. Clinical Pulmonary Medicine 2009, 16: 293-301. DOI: 10.1097/cpm.0b013e3181bdff38.
- Ober C, Chupp GL. The chitinase and chitinase-like proteins: a review of genetic and functional studies in asthma and immune-mediated diseases. Current Opinion In Allergy And Clinical Immunology 2009, 9: 401-408. PMID: 19644363, PMCID: PMC3018778, DOI: 10.1097/aci.0b013e3283306533.
- Crisafi G, Chupp G, Evans M, Sorkness R, Swenson C, Busse W, Jarjour N. Chitotriosidase Activity and YKL-40 Protein Are Increased in Severe Asthma. 2009, a5440. DOI: 10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a5440.
- Vicencio A, Tsirilakis K, Du Z, Zeng W, Kipperman S, Veler H, Chupp G, Goldman D. Chitinase Activity and YKL-40 Expression in Lungs of Children with Persistent Asthma. 2009, a4811. DOI: 10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a4811.
- O'Toole M, Bjornsdottir U, Holgate S, Reddy P, Hill A, McKee C, Csimma C, Legault H, Weaver A, Small C, Ramsey R, Ellis D, Burke C, Thompson P, Irving L, Enden J, Chupp G, Wardlaw A, Stahlman J, Raible D, Miller D, Goldman S, Ryan J, Dorner A, Immermann F. Biological Mechanism Associated with Asthma Exacerbation Attack as Revealed By Gene Expression Patterns of Peripheral Blood Mononuclear Cells. The Journal Of Allergy And Clinical Immunology 2009, 123: s154. DOI: 10.1016/j.jaci.2008.12.576.
- Ober C, Tan Z, Sun Y, Possick JD, Pan L, Nicolae R, Radford S, Parry RR, Heinzmann A, Deichmann KA, Lester LA, Gern JE, Lemanske RF, Nicolae DL, Elias JA, Chupp GL. Effect of Variation in CHI3L1 on Serum YKL-40 Level, Risk of Asthma, and Lung Function. The New England Journal Of Medicine 2008, 358: 1682-1691. PMID: 18403759, PMCID: PMC2629486, DOI: 10.1056/nejmoa0708801.
- Chupp GL, Lee CG, Jarjour N, Shim YM, Holm CT, He S, Dziura JD, Reed J, Coyle AJ, Kiener P, Cullen M, Grandsaigne M, Dombret MC, Aubier M, Pretolani M, Elias JA. A Chitinase-like Protein in the Lung and Circulation of Patients with Severe Asthma. The New England Journal Of Medicine 2007, 357: 2016-2027. PMID: 18003958, DOI: 10.1056/nejmoa073600.
- Bhandari V, Choo-Wing R, Lee CG, Zhu Z, Nedrelow JH, Chupp GL, Zhang X, Matthay MA, Ware LB, Homer RJ, Lee PJ, Geick A, de Fougerolles AR, Elias JA. Hyperoxia causes angiopoietin 2–mediated acute lung injury and necrotic cell death. Nature Medicine 2006, 12: 1286-1293. PMID: 17086189, PMCID: PMC2768268, DOI: 10.1038/nm1494.
- Khazeni N, Homer RJ, Rubinowitz AN, Chupp GL. Massive cavitary pulmonary rheumatoid nodules in a patient with HIV. European Respiratory Journal 2006, 28: 872-874. PMID: 17012633, DOI: 10.1183/09031936.06.00144105.
- Lee CG, Kang HR, Homer RJ, Chupp G, Elias JA. Transgenic Modeling of Transforming Growth Factor-β1. Annals Of The American Thoracic Society 2006, 3: 418-423. PMID: 16799085, PMCID: PMC2658706, DOI: 10.1513/pats.200602-017aw.
- Sabina AB, Williams A, Wall HK, Bansal S, Chupp G, Katz DL. Yoga intervention for adults with mild-to-moderate asthma: a pilot study. Annals Of Allergy Asthma & Immunology 2005, 94: 543-548. PMID: 15945557, DOI: 10.1016/s1081-1206(10)61131-3.
- Cohn L, Elias JA, Chupp GL. Asthma: Mechanisms of Disease Persistence and Progression. Annual Review Of Immunology 2004, 22: 789-815. PMID: 15032597, DOI: 10.1146/annurev.immunol.22.012703.104716.
- CHUPP G. PREFACE. Clinics In Chest Medicine 2001, 22: xi. DOI: 10.1016/s0272-5231(05)70054-x.
- O'Regan A, Nau G, Chupp G, Berman J. Osteopontin (Eta-1) in cell-mediated immunity: teaching an old dog new tricks. Trends In Immunology 2000, 21: 475-478. PMID: 11071524, DOI: 10.1016/s0167-5699(00)01715-1.
- Corne J, Chupp G, Lee C, Homer R, Zhu Z, Chen Q, Ma B, Du Y, Roux F, McArdle J, Waxman A, Elias J. IL-13 stimulates vascular endothelial cell growth factor and protects against hyperoxic acute lung injury. Journal Of Clinical Investigation 2000, 106: 783-791. PMID: 10995789, PMCID: PMC381393, DOI: 10.1172/jci9674.
- Nau G, Chupp G, Emile J, Jouanguy E, Berman J, Casanova J, Young R. Osteopontin Expression Correlates with Clinical Outcome in Patients with Mycobacterial Infection. American Journal Of Pathology 2000, 157: 37-42. PMID: 10880373, PMCID: PMC1850209, DOI: 10.1016/s0002-9440(10)64514-2.
- Elias J, Zhu Z, Chupp G, Homer R. Airway remodeling in asthma. Journal Of Clinical Investigation 1999, 104: 1001-1006. PMID: 10525034, PMCID: PMC408860, DOI: 10.1172/jci8124.
- Nau G, Liaw L, Chupp G, Berman J, Hogan B, Young R. Attenuated Host Resistance againstMycobacterium bovis BCG Infection in Mice Lacking Osteopontin. Infection And Immunity 1999, 67: 4223-4230. PMID: 10417195, PMCID: PMC96728, DOI: 10.1128/iai.67.8.4223-4230.1999.
- Nau G, Guilfoile P, Chupp G, Berman J, Kim S, Kornfeld H, Young R. A chemoattractant cytokine associated with granulomas in tuberculosis and silicosis. Proceedings Of The National Academy Of Sciences Of The United States Of America 1997, 94: 6414-6419. PMID: 9177232, PMCID: PMC21064, DOI: 10.1073/pnas.94.12.6414.
- Cruikshank W, Kornfeld H, Berman J, Chupp G, Keane J, Center D. Biological activity of interleukin-16. Nature 1996, 382: 501-502. PMID: 8700223, DOI: 10.1038/382501b0.
- Winchester Center for Lung DiseaseFitkin Memorial Pavilion789 Howard Avenue, Ste 2nd floorNew Haven, CT 06519
- Winchester Center for Lung DiseaseNorth Haven Medical Center6 Devine StreetNorth Haven, CT 06473
Biography
Geoffrey Chupp, MD, is a pulmonologist who specializes in lung diseases that affect the airway, including severe asthma, Chronic Obstructive Pulmonary Disease (COPD), bronchiolitis, autoimmune airway diseases, and airway diseases that have not been classified. He also specializes in eosinophilic lung diseases such as eosinophilic pneumonia, eosinophilic granulomatosis with polyangiitis (EGPA), and Allergic Bronchopulmonary Aspergillosis (ABPA).
He often helps patients who have complex disease that has been difficult to treat.
“I wanted to pursue a career in medicine to comfort people who are sick and discover the cause or causes of their disease,” says Dr. Chupp. Working with pulmonary patients is especially rewarding for a doctor, he adds. “It crosses all segments of society, so I get to meet lots of interesting people.”
Dr. Chupp came to Yale in 1997 and developed the Yale Center for Asthma & Airways Disease (YCAAD), a multidisciplinary clinical program that he still directs. The center cares for a broad spectrum of conditions and has helped patients with conditions that are difficult to diagnose, sometimes because of a co-occurring illness such as gastroesophageal reflux or sinusitis, and provides treatments that may not be available elsewhere. “We have novel biologic treatments and access to clinical trials for these patients,” he says.
Up to 20 clinical trials are active at any given time at YCAAD. This research has helped put Yale Medicine on the cutting edge of individualized asthma therapy and precision medicine for patients with asthma. “We see a future where we will be identifying a patient’s particular genetic risk factors and the molecular signals that are driving their particular disease,” says Dr. Chupp. “We will develop a combination of treatments that is personalized for every patient; it will include lifestyle recommendations, inhaled therapies, and biologic therapies that will maximally manage their disease without guesswork.”
Titles
- Professor of Medicine (Pulmonary, Critical Care and Sleep Medicine )
- Director, Yale Center for Asthma and Airways Disease (YCAAD), Pulmonary, Critical Care & Sleep Medicine
- Director, Pulmonary Function Laboratory, Yale New Haven Hospital, Pulmonary, Critical Care & Sleep Medicine
Education & Training
- MAYale University, Privatim (2017)
- ResidencyNew England Medical Center (2003)
- FellowBoston University School of Medicine (1997)
- ResidentTufts University/New England Medical Center (1993)
- InternTufts-New England Medical Center (1991)
- MDGeorge Washington University (1990)
- BSTufts University (1986)
- InternshipNew England Medical Center
Additional Information
- Yale Technology Summit: Technology Innovations Pitch Competition Award Second Place: (2017)
- Connecticut Magazine Top Docs 2016: Connecticut Magazine (2016)
- Connecticut Magazine Top Docs 2015: Connecticut Magazine (2015)
- Hero of Yale New Haven Hospital Award: (2009)
- Distinguished Service Award: Yale New Haven Hospital (2008)
- Distinguished Service Award: Yale New Haven Hospital (2007)
- Excellence in Teaching Award: Pulmonary and Critical Care Fellows), Division of Pulmonary and Critical Care Medicine (2006)
- Distinguished Service Award: Yale New Haven Hospital (2006)
- Excellence in Teaching Award: Pulmonary and Critical Care Fellows (2002)
- Loan Repayment Award: National Institutes of Health (2002)
- Skowasch D, Pavord I, Chupp G, Jackson D, Muccino D, Forth R, Kwiatek J, Vichiendilokkul A, Jackson D. Twice-yearly Depemokimab (Depe) Reduces Exacerbations and Improves Quality of Life (QoL) in Patients (Pts) With Uncontrolled Asthma Symptoms at Baseline (BL): Subgroup Analyses of the Phase III SWIFT-1/2 Studies. Pneumologie 2026, 80: s178-s179. DOI: 10.1055/s-0046-1816513.
- Denlinger L, Israel E, Moore W, Georas S, Wright R, Castro M, Peden D, Anstrom K, Bleecker E, Alexander L, Cahill K, Cardet J, Carr T, Cedano J, Chen A, Chupp G, Comhair S, DiMango E, Erzurum S, Fahy J, Fajt M, Gaston B, Jackson D, Jain S, Jarjour N, Kenyon N, Kraft M, Krishnan J, Kumar R, Lugogo N, Martinez F, Marquis M, Pappalardo A, Phipatanakul W, Rank M, Rosenberg S, Salciccioli J, Sanchez M, Smith L, Sumino K, Szefler S, Tang M, Vijayanand P, Wechsler M, Wenzel S, White S, Zeki A, Ivanova A, Bacharier L, Akuthota P, Team N, Bleecker E, Carr T, Moore W, Rank M, Camacho G, Gerald L, Hastie A, Krings J, Martinez F, Merchen J, Meyers D, Nirendran N, Ortega V, Pippins A, Rusk A, Schunk R, Skeps R, Simmons T, Williamson P, Zein J, Israel E, Cardet J, DiMango E, Phipatanakul W, Bailey J, Banzon T, Bartnikas L, Baxi S, Betapudi V, Brick I, Casale T, Cinelli M, Crestani E, Cunningham A, Esty B, Fandozzi ;, Fernandez J, Fitzpatrick E, Flam B, Forth V, Gaffin J, Gentile K, Gueye-Ndiaye S, Haley K, Heromin R, Hauptmann M, Kaage T, Kelly M, Kraemer M, LaBere B, Lai P, Le M, Ledford D, Lee J, Lee J, Lockey R, Macginnitie A, McCarty K, Moss K, Mukharesh L, Pistenmaa A, Pepper A, Pimental M, Queheillalt D, Robinson A, Salciccioli J, Saroya T, Smith C, Trevedi M, Trippa L, Tulchinsky A, Vitiello A, Yee C, Zakar K, White T, Kumar R, Moy J, Rosenberg S, Aalemansour H, Buechler K, Carter T, Fu J, Hixon J, Jackson C, Ji Y, Johnson C, Kalhan R, Kane J, Kaur O, Li G, Lippner E, Makhija M, Maleckar S, Naureckas E, Nyenhuis S, Peters A, Press V, Qureshi M, Ryba D, Sheng J, Smith L, Xu B, Wechsler M, Szefler S, Chupp G, Holguin F, Kraft M, Liu A, Rogers L, Anderson D, Belimezova S, Bitzan J, Bose S, Brock J, Sanchez J, Clark B, Cohn L, Cotarian A, Cruse M, Eisenberg E, Estrom J, Glassmeyer I, Villalobos J, Grant N, Gruberg B, Guntur V, Hay O, Hills A, Hsieh J, Kessler J, Kolakowski C, Miyazawa N, Pak J, Pruitt D, Rhoads S, Sharma S, Stevens A, Tippin B, Valente C, Vicencio A, Wainscoat C, Weber J, Wessels G, White M, Winnica D, Zeitlin P, Denlinger L, Jarjour N, Krishnan J, Agnihotri N, Bach J, Bires N, DeLisa J, Fichtinger P, Floerke H, Fritz B, Grogan J, Guadarrama A, Hasse W, Jackson D, Kaspari R, Kelley R, Klaus D, Lowell P, Larson L, Norwick L, O’Brien M, Palas T, Pappalardo A, Read E, Schraml A, Schiebler M, Sorkness R, Tattersall M, Wollet L, Gaston B, Erzurum S, Teague W, Chmiel J, Ross K, Aronica M, Beck B, Bendy L, Borish L, Chedraoui C, Comhair S, Davis M, Dix A, Fakhry B, Gammell R, Gluvna A, Hamm E, Heskett M, Hu B, Khatri S, Kirwan J, Kloepfer K, Koo M, Labadia M, Marko A, Matheis N, Mey J, Mulya A, Murphy D, Owensby R, Parker L, Pennington E, Roesch E, Sharp J, Smith C, Solanki N, Veri L, Shifflett K, Yang F, Wenzel S, Lugogo N, Bagheri A, Cislo L, Fajt M, Gauthier M, Hadden M, James P, Mohan A, Moore J, Nouraie S, Ramonell R, Romanek R, Sullivan L, Trudeau J, Zhang M, Akuthota P, Jain S, Vijayanand P, Barry J, Beg N, Brickner H, Alexander L, Diaz D, Jafari Y, McKeon N, Fahy J, Kenyon N, Almario M, Charbit A, Cho L, Gale B, Haczku A, Harper R, Houston T, Kain C, Kivler C, Kuhn B, Liu M, McCourt P, Miller J, Nguyen A, Orain X, Peters M, Plough A, Ramirez K, Rossi L, Schivo M, Singapuri M, Teuber S, Tham T, Tompkins D, Vi J, Zeki A, Castro M, Bacharier L, Sumino K, Atha J, Boomer J, Cahill K, Clover A, Dorman V, Hoffman E, Jackson F, Klinck M, Krings J, Madison J, Quigley J, Quinones T, Saxena S, Sharpe M, Troyer J, Yen-Declue H, Zulich A, Ivanova A, Anstrom K, LaVange L, Bagaason S, Britt A, Bryan H, Burbank A, Chen A, Culpepper C, DeMarcus F, Fenu C, Gotman N, Green R, Harrison L, James J, Kosorok J, Kosorok M, Littleton L, Marquis M, O'Neal W, Peden D, Price R, Quibrera P, Ritz C, Sanchez M, Schwartz S, Slye N, Song T, Wilson N, Croxton T, Lu J, Noel P, Bamdad J, Georas S, Wright R. PrecISE- A Biomarker Stratified Adaptive Trial of 5 Interventions in Severe Asthma: Final Protocol and the Baseline Cohort. The Journal Of Allergy And Clinical Immunology 2026 PMID: 41707916, DOI: 10.1016/j.jaci.2026.02.001.
- Chupp G, Nagase H, Skowasch D, Devouassoux G, Côté A, Jackson D, Jackson D, Wechsler M, Imber V, McGinniss J, K S, Howarth P, Pavord I. Switching to twice-yearly depemokimab from mepolizumab/benralizumab in severe asthma: A multicenter, randomized, double-blind, Phase 3A Clinical Trial (NIMBLE). American Journal Of Respiratory And Critical Care Medicine 2026 PMID: 41738176, DOI: 10.1093/ajrccm/aamag031.
- Kay S, Rajeevan H, Son M, Kwah J, Ramirez M, Liu Y, Wang Z, Yan X, Nino G, Britto C, Chupp G, Gomez J. Sex-biased Gene Expression Underlies Immune Dysfunction in Asthma. American Journal Of Respiratory Cell And Molecular Biology 2025, 73: 884-896. PMID: 40587876, DOI: 10.1165/rcmb.2024-0565oc.
- Zidan E, Ahn J, Kang I, Chupp G, Shin J. SYSTEMATIC REVIEW ON THE PREVALENCE OF IMMUNOGLOBULIN G SUBCLASS DEFICIENCIES IN PATIENTS WITH ASTHMA. Annals Of Allergy Asthma & Immunology 2025, 135: s50. DOI: 10.1016/j.anai.2025.08.156.
- Lugogo N, Carr T, White A, Chupp G, Chase N, Lanz M, Marchese C, Lindsley A, Lal H, Ambrose C. TEZEPELUMAB EFFICACY IN PATIENTS WITH SEVERE, UNCONTROLLED ASTHMA BY EXACERBATION TRIGGERS IN NAVIGATOR AND DIRECTION. Annals Of Allergy Asthma & Immunology 2025, 135: s47. DOI: 10.1016/j.anai.2025.08.150.
- CHUPP G, BERNSTEIN D, JACQUES L, ZHU C, VICHIENDILOKKUL A, HOWARTH P, KWIATEK J, WECHSLER M, PAVORD I. TWICE-YEARLY DEPEMOKIMAB REDUCES NEED FOR BURST ORAL CORTICOSTEROID USE IN PATIENTS WITH ASTHMA: POSTHOC ANALYSES OF THE PHASE III SWIFT-1/2 STUDIES. Chest 2025, 168: a1-a3. DOI: 10.1016/j.chest.2025.07.007.
- CRINER G, CHUPP G, HAN M, SINGH D, MARCHESE C, MOLFINO N, MATSUNAGA Y, PONNARAMBIL S, AMBROSE C. EFFECT OF TEZEPELUMAB ON SYSTEMIC CORTICOSTEROID USE FOR EXACERBATIONS IN PATIENTS WITH MODERATE TO VERY SEVERE COPD BY BLOOD EOSINOPHIL COUNT. Chest 2025, 168: a7259-a7263. DOI: 10.1016/j.chest.2025.09.078.
- Chupp G, Hui C, Christenson S, Israel E, Janssens W, Kocks J, Siddiqui S, Haughney J, Topole E, Da Silva C, Bolton C. Survey evaluating CompEx Asthma components, and current and future digital enablers. 2025, pa1483. DOI: 10.1183/13993003.congress-2025.pa1483.
- Canonica G, Bagnasco D, Lee J, Chupp G, Schleich F, Oppenheimer J, Zhang L, Alfonso-Cristancho R, Howarth P. Mepolizumab in patients with severe asthma and blood eosinophil counts between 150 and 300 cells per µL: benefits at two years. ERJ Open Research 2025, 11: 01390-2024. PMID: 41220814, PMCID: PMC12598589, DOI: 10.1183/23120541.01390-2024.
- Impact of Demographics on Mepolizumab Effectiveness in Severe Asthma: One-Year REALITI-A SubanalysisChupp G, Heaney L, Pelaia G, Almonacid C, Maxwell A, Zhang L, Alfonso-Cristancho R, Howarth P, Brusselle G. Impact of Demographics on Mepolizumab Effectiveness in Severe Asthma: One-Year REALITI-A Subanalysis. The Journal Of Allergy And Clinical Immunology In Practice 2025, 13: 3286-3295. PMID: 40780384, DOI: 10.1016/j.jaip.2025.07.049.
- Zielonka J, Kay S, Chupp G, Gomez J. The Role of Non-coding RNAs in Asthma T2-high and T2-low Endotypes. American Journal Of Respiratory And Critical Care Medicine 2025, 211: a3430-a3430. DOI: 10.1164/ajrccm.2025.211.abstracts.a3430.
- Hadikhani P, Yan X, Chupp G, Liu Q, Ban G, Piparia S, Mcgeachie M, Sharma R, Weiss S, Kho A, Tantisira K. Asthma Exacerbations: Integrative Analysis of Mirna Activity in Using Single-cell Transcriptomics. American Journal Of Respiratory And Critical Care Medicine 2025, 211: a7773-a7773. DOI: 10.1164/ajrccm.2025.211.abstracts.a7773.
- Pavord I, Chupp G, Jackson D, Muccino D, Forth R, Kwiatek J, Vichiendilokkul A, Jackson D. Twice-yearly Depemokimab Reduces Exacerbations and Improves Quality of Life in Patients With Uncontrolled Asthma Symptoms at Baseline: Subgroup Analyses of the Phase III SWIFT-1/2 Studies. American Journal Of Respiratory And Critical Care Medicine 2025, 211: a5234-a5234. DOI: 10.1164/ajrccm.2025.211.abstracts.a5234.
- Criner G, Chupp G, Han M, Martin N, Molfino N, Ambrose C, Sindhwani N, Ponnarambil S. Improvements in St George's Respiratory Questionnaire Domain Scores With Tezepelumab Versus Placebo in Patients With Moderate to Very Severe Chronic Obstructive Pulmonary Disease: Results From the Phase 2a COURSE Study. American Journal Of Respiratory And Critical Care Medicine 2025, 211: a4031-a4031. DOI: 10.1164/ajrccm.2025.211.abstracts.a4031.
- Han M, Drummond M, Criner G, Chupp G, Martin N, Molfino N, Ambrose C, Sindhwani N, Ponnarambil S. Effect of Tezepelumab on Exacerbations in Patients With Moderate to Very Severe Chronic Obstructive Pulmonary Disease Based on Inclusion or Exclusion of Antibiotic Use in the Definition of Moderate Exacerbations: Data From the Phase 2a COURSE Study. American Journal Of Respiratory And Critical Care Medicine 2025, 211: a4026-a4026. DOI: 10.1164/ajrccm.2025.211.abstracts.a4026.
- Bazan I, Chupp G, Duan L, Pelletier M, Carstens D, Ambrose C. The Impact of Race-Neutral Reference Pulmonary Function Equations Among Us Patients With Severe Asthma: Results from the Chronicle Study. American Journal Of Respiratory And Critical Care Medicine 2025, 211: a1047-a1047. DOI: 10.1164/ajrccm.2025.211.abstracts.a1047.
- Zaeh S, Hay O, Zimmerman Z, Chupp G, Eakin M. Barriers and Facilitators to Transitioning to Maintenance and Reliever Therapy for Patients With Moderate to Severe Asthma. American Journal Of Respiratory And Critical Care Medicine 2025, 211: a1473-a1473. DOI: 10.1164/ajrccm.2025.211.abstracts.a1473.
- Liu M, Chaudhuri R, Chupp G, Heaney L, Lee J, Pilette C, Brusselle G, Alfonso-Cristancho R, Zhang L, Howarth P, Kumar A. Impact of atopic status, prior omalizumab use and baseline blood eosinophil count alone and in combination with total serum IgE on maintenance OCS reduction outcomes in patients with severe asthma treated with mepolizumab in the REALITI-A study. Revue Française D'Allergologie Et D'Immunologie Clinique 2025, 65: 104319. DOI: 10.1016/j.reval.2025.104319.
- Caruso C, Canonica G, Patel M, Smith A, Liu M, Alfonso-Cristancho R, Price R, Jakes R, Demetriou L, Valero A, Köhler T, Pilette C, Chupp G, Brusselle G, Howarth P. Prospective REALITI-A Study 2-Year Real-World Benefits of Mepolizumab in Severe Asthma. CHEST Pulmonary 2025, 3: 100107. DOI: 10.1016/j.chpulm.2024.100107.
- Cardet J, Bailey J, Hurley L, Maher N, Staton E, Yawn B, Zaeh S, Israel E, investigators; O, Apter A, Bradford P, Calderon-Candelario R, Carroll J, Chupp G, Cohen R, Ericson B, Fuhlbrigge A, Kaplan B, Kruse J, Nazario S, Pace W, Pasarica M, Phipatanakul W, Riley I, Rodriguez-Louis J, Shenoy K, Stranges P, Tapp H, Wechsler M. Maintenance of an Asthma Intervention Post-Trial: Use of a Patient-Activated Reliever-Triggered Inhaled Corticosteroid (PARTICS) Strategy in Black and Latinx Patients. The Journal Of The American Board Of Family Medicine 2025, 38: 378-382. PMID: 40578913, PMCID: PMC12616832, DOI: 10.3122/jabfm.2024.240014r2.
- Lugogo N, Peters A, Chupp G, Wechsler M, Caveney S, Martin N, Parikh B, Ambrose C. Réponses cliniques au tézépélumab chez des patients souffrant d’asthme sévère non contrôlé avec des antécédents de polypose nasosinusienne, d’après l’étude NAVIGATOR. Revue Des Maladies Respiratoires Actualités 2025, 17: 212. DOI: 10.1016/j.rmra.2024.11.445.
- Israel E, Chupp G, Lugogo N, Llanos J, Martin N, Martin N, Ambrose C, Jackson D. P23 Asthma exacerbation rates as a function of biomarker levels 4 weeks after initiation of tezepelumab treatment: an analysis of the NAVIGATOR study. 2024, a121-a122. DOI: 10.1136/thorax-2024-btsabstracts.184.
- Lugogo N, Chupp G, Corren J, Israel E, Molfino N, Martin N, Spahn J, Ambrose C. TEZEPELUMAB EFFECTS ON INFLAMMATORY BIOMARKERS IN PATIENTS WITH SEVERE, UNCONTROLLED ASTHMA BY BASELINE BIOMARKER LEVEL. Annals Of Allergy Asthma & Immunology 2024, 133: s53-s54. DOI: 10.1016/j.anai.2024.08.184.
- Zidan E, Wilson G, Shin J, Chupp G. The next frontier Defining and optimizing treatments for patients with type 2 low asthma. Annals Of Allergy Asthma & Immunology 2024, 134: 3-4. PMID: 39414022, DOI: 10.1016/j.anai.2024.10.013.
- Buchheit K, Shaw D, Chupp G, Lehtimaki L, Heffler E, Finney‐Hayward T, Zangrilli J, Kwiatek J, Siddiqui S, Roufosse F, Thamboo A, West N, Vichiendilokkul A, Hellings P, Peters A, Howarth P. Interleukin‐5 as a pleiotropic cytokine orchestrating airway type 2 inflammation: Effects on and beyond eosinophils. Allergy 2024, 79: 2662-2679. PMID: 39359069, DOI: 10.1111/all.16303.
- WECHSLER M, CHUPP G, ISRAEL E, CASTRO M, BOBER M, LINDSLEY A, SPAHN J, AMBROSE C. EFFICACY OF TEZEPELUMAB IN PATIENTS WITH SEVERE, UNCONTROLLED ASTHMA AND ALLERGIC RHINITIS GROUPED BY BASELINE BLOOD EOSINOPHIL COUNT: POOLED ANALYSIS OF PATHWAY AND NAVIGATOR. Chest 2024, 166: a4664-a4680. DOI: 10.1016/j.chest.2024.06.2821.
- Pavord I, Howarth P, Chan R, Yang S, Kolterer S, Zhang L, Chupp G. Mepolizumab in patients with asthma and features of COPD: A MENSA/MUSCA post hoc analysis. 2024, pa4492. DOI: 10.1183/13993003.congress-2024.pa4492.
- Wilson G, Gautam S, Chupp G. Does Eosinophil Heterogeneity Translate into Functional Diversity? A Review of the Evolving Paradigm of Eosinophil Heterogeneity in Asthma. Biomedicines 2024, 12: 2011. PMID: 39335525, PMCID: PMC11428232, DOI: 10.3390/biomedicines12092011.
- Zaeh S, Zimmerman Z, Eakin M, Chupp G. Adoption and implementation of maintenance and reliever therapy for adults with moderate-to-severe asthma. Annals Of Allergy Asthma & Immunology 2024, 133: 318-324. PMID: 38897404, PMCID: PMC11344662, DOI: 10.1016/j.anai.2024.06.011.
- Carr T, Moore W, Kraft M, Brusselle G, Castro M, Chupp G, Wechsler M, Hunter G, Lindsley A, Llanos J, Burke L, Chandarana S, Ambrose C. Efficacy of Tezepelumab in Patients with Severe, Uncontrolled Asthma Across Multiple Clinically Relevant Subgroups in the NAVIGATOR Study. Advances In Therapy 2024, 41: 2978-2990. PMID: 38802635, PMCID: PMC11213736, DOI: 10.1007/s12325-024-02889-8.
- Chupp G, Murphy K, Gandhi H, Gilbert I, Bleecker E. Asthma control in the United States Relationships between short-acting β2-agonist and systemic corticosteroid use. Annals Of Allergy Asthma & Immunology 2024, 133: 302-309. PMID: 38740134, DOI: 10.1016/j.anai.2024.05.003.
- Lugogo N, Peters A, Chupp G, Wechsler M, Caveney S, Martin N, Parikh B, Ambrose C. Clinical Responses to Tezepelumab in Patients With Severe, Uncontrolled Asthma, and a History of Nasal Polyps from the NAVIGATOR Study. American Journal Of Respiratory And Critical Care Medicine 2024, 209: a5251-a5251. DOI: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a5251.
- Liu M, Chaudhuri R, Chupp G, Heaney L, Lee J, Pilette C, Brusselle G, Cristancho R, Zhang L, Howarth P. Impact of Atopic Status, Prior Omalizumab Use and Baseline Blood Eosinophil Count Alone and in Combination With Total Serum IgE on Maintenance OCS Reduction Outcomes in Patients With Severe Asthma Treated With Mepolizumab in the REALITI-A Study. American Journal Of Respiratory And Critical Care Medicine 2024, 209: a5376-a5376. DOI: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a5376.
- Israel E, Chupp G, Lugogo N, Llanos J, Martin N, Martin N, Ambrose C, Jackson D. Asthma Exacerbation Rates as a Function of Biomarker Levels 4 Weeks After Initiation of Tezepelumab Treatment: An Analysis of the NAVIGATOR Study. American Journal Of Respiratory And Critical Care Medicine 2024, 209: a6704-a6704. DOI: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a6704.
- Wilson G, Liu Q, Gautam S, Knight J, Shelar A, Stewart E, Visness C, Sanders J, Gill M, Gruchalla R, Liu A, Kattan M, Hershey G, Togias A, Becker P, Altman M, Busse W, Jackson D, Montgomery R, Chupp G. Innate Immune Mechanisms Associated With Exacerbations on Mepolizumab. American Journal Of Respiratory And Critical Care Medicine 2024, 209: a6984-a6984. DOI: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a6984.
- Krishna N, Goss J, Dell L, Vazifedan T, Chupp G, Thienel U, Cunnion K. RLS-0071 Independently Inhibits Neutrophil Migration and Myeloperoxidase Activity and NETosis in Humans Challenged With LPS by Inhalation. American Journal Of Respiratory And Critical Care Medicine 2024, 209: a6690-a6690. DOI: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a6690.
- Zimmerman Z, Eakin M, Chupp G, Zaeh S. Utilization of Single Maintenance and Reliever Therapy (SMART) for Moderate and Severe Asthma. American Journal Of Respiratory And Critical Care Medicine 2024, 209: a6601-a6601. DOI: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a6601.
- Bourdin A, Chupp G, Jackson D, Cohen D, Emerath U, Shavit A, Kurdyukova Y, Menzies-Gow A. MELTEMI and COLUMBA: 5-Year Comparative Safety Analysis of Benralizumab and Mepolizumab. The Journal Of Allergy And Clinical Immunology In Practice 2024, 12: 2074-2083.e4. PMID: 38677588, DOI: 10.1016/j.jaip.2024.04.033.
- Wilson G, Knight J, Liu Q, Shelar A, Stewart E, Wang X, Yan X, Sanders J, Visness C, Gill M, Gruchalla R, Liu A, Kattan M, Khurana Hershey G, Togias A, Becker P, Altman M, Busse W, Jackson D, Montgomery R, Chupp G. Activated sputum eosinophils associated with exacerbations in children on mepolizumab. The Journal Of Allergy And Clinical Immunology 2024, 154: 297-307.e13. PMID: 38485057, PMCID: PMC11305967, DOI: 10.1016/j.jaci.2024.01.031.
- Busse W, Chupp G, Corbridge T, Stach-Klysh A, Oppenheimer J. Targeting Asthma Remission as the Next Therapeutic Step Toward Improving Disease Control. The Journal Of Allergy And Clinical Immunology In Practice 2024, 12: 894-903. PMID: 38320720, DOI: 10.1016/j.jaip.2024.01.044.
- Chupp G, Baudy P, Carstens D, North B, Danka M, Roy S, Marshall H, Merkel P. Utilizing Machine Learning with Claims Data to Diagnose and Quantify the Prevalence of Eosinophilic Granulomatosis with Polyangiitis. The Journal Of Allergy And Clinical Immunology 2024, 153: ab215. DOI: 10.1016/j.jaci.2023.11.694.
- Zaeh S, Eakin M, Chupp G. Implementing Antiinflammatory Reliever Strategies in Asthma The Evolving Paradigm of Asthma Management. Chest 2024, 165: 250-252. PMID: 38336438, DOI: 10.1016/j.chest.2023.09.004.
- Chupp G, Alobid I, Lugogo N, Kariyawasam H, Bourdin A, Chaker A, Smith S, Sousa A, Mayer B, Chan R, Matucci A, Chachuat L. Mépolizumab est associé à des bénéfices cliniques chez les patients atteints de polypose nasosinusienne, indépendamment de l’utilisation antérieure de corticostéroïdes systémiques. Revue Des Maladies Respiratoires Actualités 2024, 16: 188-189. DOI: 10.1016/j.rmra.2023.11.387.
- Brusselle G, Lougheed D, Canonica G, Munoz-Esquerre M, Heaney L, Price R, Howarth P, Raimondi A, Gardiner F, Chupp G, Welte T, Picaud C. Obtention d’une rémission clinique dans l’asthme sévère après un traitement par mépolizumab : résultats de l’étude REALITI-A à 2 ans. Revue Des Maladies Respiratoires Actualités 2024, 16: 192-193. DOI: 10.1016/j.rmra.2023.11.393.
- Gautam S, Chu J, Cohen A, Kaur R, Lee S, Wilson G, Liu Q, Gomez J, Rajaveen H, Yan X, Cohn L, Clark B, Chupp G. Sputum alarmins delineate distinct T2 cytokine pathways and unique subtypes of patients with asthma. Allergy 2023, 78: 3274-3277. PMID: 37874609, PMCID: PMC10842366, DOI: 10.1111/all.15915.
- Liu Y, Zhao J, Adams T, Wang N, Schupp J, Wu W, McDonough J, Chupp G, Kaminski N, Wang Z, Yan X. Correction: iDESC: identifying differential expression in single-cell RNA sequencing data with multiple subjects. BMC Bioinformatics 2023, 24: 394. PMID: 37858060, PMCID: PMC10588114, DOI: 10.1186/s12859-023-05523-6.
- MOORE W, LUGOGO N, CHUPP G, MARTIN N, AMBROSE C, COOK W, ACKERT J. EFFICACY OF TEZEPELUMAB IN PATIENTS WITH SEVERE, UNCONTROLLED ASTHMA WITH COMORBID GASTROESOPHAGEAL REFLUX DISEASE: A POOLED ANALYSIS OF THE PATHWAY AND NAVIGATOR STUDIES. Chest 2023, 164: a4-a7. DOI: 10.1016/j.chest.2023.07.073.
- CHUPP G, LUGOGO N, WECHSLER M, LAWSON K, LINDSLEY A, SPAHN J, AMBROSE C. LONG-TERM EFFICACY OF TEZEPELUMAB IN PATIENTS WITH SEVERE, UNCONTROLLED ASTHMA BY BASELINE BODY MASS INDEX. Chest 2023, 164: a9-a14. DOI: 10.1016/j.chest.2023.07.075.
- Oppenheimer J, Carrillo Díaz T, Martínez Moragón E, Sanchez Herrero M, Bañas Conejero D, Chupp G, Price R, Raimondi A, Zhang S, Howarth P, Domingo Ribas C. Late Breaking Abstract - Clinical remission with mepolizumab in severe asthma: impact of lung function parameters. 2023, pa646. DOI: 10.1183/13993003.congress-2023.pa646.
- iDESC: identifying differential expression in single-cell RNA sequencing data with multiple subjectsLiu Y, Zhao J, Adams T, Wang N, Schupp J, Wu W, McDonough J, Chupp G, Kaminski N, Wang Z, Yan X. iDESC: identifying differential expression in single-cell RNA sequencing data with multiple subjects. BMC Bioinformatics 2023, 24: 318. PMID: 37608264, PMCID: PMC10463720, DOI: 10.1186/s12859-023-05432-8.
- Chupp G, Alobid I, Lugogo N, Kariyawasam H, Bourdin A, Chaker A, Smith S, Sousa A, Mayer B, Chan R, Matucci A. Mepolizumab Reduces Systemic Corticosteroid Use in Chronic Rhinosinusitis With Nasal Polyps. The Journal Of Allergy And Clinical Immunology In Practice 2023, 11: 3504-3512.e2. PMID: 37586475, DOI: 10.1016/j.jaip.2023.08.015.
- Liu Y, Rajeevan H, Simonov M, Lee S, Wilson F, Desir G, Vinetz J, Yan X, Wang Z, Clark B, Possick J, Price C, Lutchmansingh D, Ortega H, Zaeh S, Gomez J, Cohn L, Gautam S, Chupp G. Differences in Mortality Among Patients With Asthma and COPD Hospitalized With COVID-19. The Journal Of Allergy And Clinical Immunology In Practice 2023, 11: 3383-3390.e3. PMID: 37454926, PMCID: PMC10787810, DOI: 10.1016/j.jaip.2023.07.006.
- Zaeh S, Chupp G, Eakin M. Is there a best strategy to prevent asthma exacerbations in inner-city patients with asthma? Annals Of Allergy Asthma & Immunology 2023, 132: 11-12. PMID: 37433383, PMCID: PMC10774450, DOI: 10.1016/j.anai.2023.07.003.
- Corren J, Menzies-Gow A, Chupp G, Israel E, Korn S, Cook B, Ambrose C, Hellqvist Å, Roseti S, Molfino N, Llanos J, Martin N, Bowen K, Griffiths J, Parnes J, Colice G. Efficacy of Tezepelumab in Severe, Uncontrolled Asthma: Pooled Analysis of the PATHWAY and NAVIGATOR Clinical Trials. American Journal Of Respiratory And Critical Care Medicine 2023, 208: 13-24. PMID: 37015033, PMCID: PMC10870853, DOI: 10.1164/rccm.202210-2005oc.
- Menzies-Gow A, Bourdin A, Chupp G, Israel E, Hellqvist Å, Hunter G, Roseti S, Ambrose C, Llanos J, Cook B, Corren J, Colice G. Effect of tezepelumab on healthcare utilization in patients with severe, uncontrolled asthma The NAVIGATOR study. Annals Of Allergy Asthma & Immunology 2023, 131: 343-348.e2. PMID: 37263380, DOI: 10.1016/j.anai.2023.05.028.
- Rabe K, Pavord I, Busse W, Chupp G, Izuhara K, Altincatal A, Gall R, Pandit‐Abid N, Deniz Y, Rowe P, Jacob‐Nara J, Radwan A. Dupilumab improves long‐term outcomes in patients with uncontrolled, moderate‐to‐severe GINA‐based type 2 asthma, irrespective of allergic status. Allergy 2023, 78: 2148-2156. PMID: 37073882, DOI: 10.1111/all.15747.
- Liu Y, Rajeevan H, Simonov M, Wilson F, Desir G, Vinetz J, Yan X, Wang Z, Clark B, Possick J, Price C, Lutchmansingh D, Gomez J, Cohn L, Gautam S, Chupp G. Mortality Differences Among Patients with Airway Disease Hospitalized with COVID-19. American Journal Of Respiratory And Critical Care Medicine 2023, 207: a6297-a6297. DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6297.
- Zaeh S, Eakin M, Chupp G. Clinical Practices and Barriers to the Use of Single Maintenance and Reliever Therapy for Asthma. American Journal Of Respiratory And Critical Care Medicine 2023, 207: a6006-a6006. DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6006.
- Wilson G, Liu Q, Knight J, Shelar A, Stewart E, Visness C, Sanders J, Gill M, Gruchalla R, Liu A, Kattan M, Hershey G, Togias A, Becker P, Altman M, Busse W, Jackson D, Montgomery R, Chupp G. Functional Analysis of Sputum Eosinophil Subpopulations in Children with Asthma. American Journal Of Respiratory And Critical Care Medicine 2023, 207: a3016-a3016. DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3016.
- Chupp G, Liu Q, Adams T, Schupp J, Wilson G, Grant N, Gomez J, Cohn L, Kaminski N, Akuthota P, Weiss S, Glass K, Bleecker E, Meyers D, Tantisira K, Yan X. Activation of Adam12-SDC4 and CCL22-CCR4 Pathways in the Airway in Asthma. American Journal Of Respiratory And Critical Care Medicine 2023, 207: a5689-a5689. DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a5689.
- Brusselle G, Lougheed M, Canonica G, Munoz-Esquerre M, Heaney L, Price R, Howarth P, Raimondi A, Gardiner F, Chupp G, Welte T. Clinical Remission Achievement in Severe Asthma Following Mepolizumab Treatment: Results from the REALITI-A Study at 2 Years. American Journal Of Respiratory And Critical Care Medicine 2023, 207: a5985-a5985. DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a5985.
- Kraft M, Chupp G, Reeh K, Lindsley A, Cook B, Hunter G, Ambrose C. Efficacy of Tezepelumab in Patients with Severe, Uncontrolled Asthma by Sex: Results from the Phase 3 Navigator Study. American Journal Of Respiratory And Critical Care Medicine 2023, 207: a4751-a4751. DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4751.
- Merkel P, Gandhi H, Genofre E, North B, Danka M, Roy S, Marshall H, Chupp G. Establishing a Diagnosis and the Prevalence of Eosinophilic Granulomatosis with Polyangiitis Through Claims Data Using Machine Learning. American Journal Of Respiratory And Critical Care Medicine 2023, 207: a4830-a4830. DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4830.
- Pavord I, Gardiner F, Heaney L, Domingo C, Price R, Pullan A, Oppenheimer J, Brusselle G, Nagase H, Chupp G, Pizzichini E, Bañas-Conejero D, Howarth P. Remission outcomes in severe eosinophilic asthma with mepolizumab therapy: Analysis of the REDES study. Frontiers In Immunology 2023, 14: 1150162. PMID: 37122713, PMCID: PMC10131245, DOI: 10.3389/fimmu.2023.1150162.
- Chupp G, Heaney L, Price R, Brusselle G, Gardiner F, Raimondi A, Chaudhuri R, Howarth P. Real-World Impact of Mepolizumab on the Oral Corticosteroid Freedom Component of Clinical Remission in Severe Eosinophilic Asthma: International, Prospective REALITI-A Study. The Journal Of Allergy And Clinical Immunology 2023, 151: ab20. DOI: 10.1016/j.jaci.2022.12.066.
- Corren J, Wechsler M, Chupp G, Roseti S, Hellqvist Å, Martin N, Llanos J, Ambrose C, Colice G. Efficacy and safety of tezepelumab in patients with uncontrolled disease while receiving maintenance therapy for moderate or severe asthma. The Journal Of Allergy And Clinical Immunology In Practice 2022, 11: 943-945.e2. PMID: 36375743, DOI: 10.1016/j.jaip.2022.10.042.
- Ortega H, Katz L, Chupp G. Asthma exacerbations during the pandemic: Time to rethink clinical markers. Journal Of Allergy And Clinical Immunology Global 2022, 2: 97-100. PMID: 36281240, PMCID: PMC9581642, DOI: 10.1016/j.jacig.2022.09.003.
- BUSSE W, CHUPP G, STANALAND M, CRAWFORD J, SLADE D. CAPTAIN: EFFECTS OF AGE AS A CONTINUOUS VARIABLE ON ASTHMA CONTROL. Chest 2022, 162: a1939-a1940. DOI: 10.1016/j.chest.2022.08.1604.
- CORREN J, WECHSLER M, CHUPP G, AMBROSE C, ROSETI S, HELLQVIST Å, ACKERT J, MARTIN N, COLICE G. EFFICACY OF TEZEPELUMAB IN PATIENTS WITH UNCONTROLLED ASTHMA DESPITE RECEIVING TREATMENT FOR MODERATE OR SEVERE DISEASE: POOLED ANALYSIS OF PATHWAY AND NAVIGATOR STUDIES. Chest 2022, 162: a21-a22. DOI: 10.1016/j.chest.2022.08.018.
- Ayala A, Yin H, Khanal S, Niu N, Nunez M, Chupp G, Laguna T, Britto C. 117 Interleukin-6 and short-palate lung and nasal epithelium clone 1 fluctuations as sex-specific markers of acute cystic fibrosis exacerbation. Journal Of Cystic Fibrosis 2022, 21: s69. DOI: 10.1016/s1569-1993(22)00808-6.
- Shlipak M, Sheshadri A, Hsu F, Chen S, Jotwani V, Tranah G, Fielding R, Liu C, Ix J, Coca S, Pahor M, Guralnik J, Leeuwenburgh C, Caudle C, Crump L, Holmes L, Leeuwenburgh J, Lu C, Miller M, Espeland M, Ambrosius W, Applegate W, Beavers D, Byington R, Cook D, Furberg C, Harvin L, Henkin L, Hepler J, Hsu F, Lovato L, Roberson W, Rushing J, Rushing S, Stowe C, Walkup M, Hire D, Rejeski W, Katula J, Brubaker P, Mihalko S, Jennings J, Hadley E, Romashkan S, Patel K, Bonds D, McDermott M, Spring B, Hauser J, Kerwin D, Domanchuk K, Graff R, Rego A, Church T, Blair S, Myers V, Monce R, Britt N, Harris M, McGucken A, Rodarte R, Millet H, Tudor-Locke C, Butitta B, Donatto S, Cocreham S, King A, Castro C, Haskell W, Stafford R, Pruitt L, Berra K, Yank V, Fielding R, Nelson M, Folta S, Phillips E, Liu C, McDavitt E, Reid K, Kirn D, Pasha E, Kim W, Beard V, Tsiroyannis E, Hau C, Manini T, Anton S, Nayfield S, Buford T, Marsiske M, Sandesara B, Knaggs J, Lorow M, Marena W, Korytov I, Morris H, Fitch M, Singletary F, Causer J, Radcliff K, Newman A, Studenski S, Goodpaster B, Glynn N, Lopez O, Nadkarni N, Williams K, Newman M, Grove G, Bonk J, Rushing J, Kost P, Ives D, Kritchevsky S, Marsh A, Brinkley T, Demons J, Sink K, Kennedy K, Shertzer-Skinner R, Wrights A, Fries R, Barr D, Gill T, Axtell R, Kashaf S, de Rekeneire N, McGloin J, Wu K, Shepard D, Fennelly B, Iannone L, Mautner R, Sweeney Barnett T, Halpin S, Brennan M, Bugaj J, Zenoni M, Mignosa B, Williamson J, Hendrie H, Rapp S, Verghese J, Woolard N, Espeland M, Jennings J, Wilson V, Pepine C, Ariet M, Handberg E, Deluca D, Hill J, Szady A, Chupp G, Flynn G, Hankinson J, Vaz Fragoso C, Groessl E, Kaplan R. Effect of Structured, Moderate Exercise on Kidney Function Decline in Sedentary Older Adults. JAMA Internal Medicine 2022, 182: 650-659. PMID: 35499834, PMCID: PMC9062767, DOI: 10.1001/jamainternmed.2022.1449.
- Korde A, Haslip M, Ahangari F, Pober J, Chupp G, Manes P, Gonzalez A, Takyar S. Endothelial Thrombopoietin Receptor Controls Eosinophil Trafficking in Asthma and Chronic Rhinosinusitis. American Journal Of Respiratory And Critical Care Medicine 2022, 205: a5684-a5684. DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5684.
- Rothenberg M, Roufosse F, Faguer S, Gleich G, Steinfeld J, Yancey S, Mavropoulou E, Kwon N, Group H, García G, Sosso A, Wehbe L, Yañez A, Blockmans D, Roufosse F, Antila M, Blanco D, Grava S, Lima M, Pez A, Faguer S, Hamidou M, Kahn J, Lefévre G, Brockow K, Kern P, Reiter A, Walz B, Welte T, Pane F, Vannucchi A, Cerino-Javier R, Gazca-Aguilar A, Hernández-Colín D, Valdéz-López H, Kupryś-Lipińska I, Musial J, Prejzner W, Mihaly E, Popov V, Zdrenghea M, Gritsaev S, Ivanov V, Tsyba N, Alonso A, Xutgla M, Fox M, Delgado R, Rivas J, Santillana G, González A, Wardlaw A, Akuthota P, Butterfield J, Chupp G, Cox J, Gleich G, Jhaveri D, Rothenberg M. Mepolizumab Reduces Hypereosinophilic Syndrome Flares Irrespective of Blood Eosinophil Count and Interleukin-5. The Journal Of Allergy And Clinical Immunology In Practice 2022, 10: 2367-2374.e3. PMID: 35568330, DOI: 10.1016/j.jaip.2022.04.037.
- Menzies-Gow A, Bourdin A, Cook W, Ambrose C, Chupp G, Kmita K, Lanos-Ackert J, Colice G. Effect of tezepelumab on exacerbation-related oral corticosteroid use in NAVIGATOR. Pneumologie 2022, 76: s12-s13. DOI: 10.1055/s-0042-1747713.
- Wilson G, Liu Q, Knight J, Visness C, Villarreal M, Gill M, Gruchalla R, Liu A, Kattan M, Hershey G, Togias A, Becker P, Altman M, Busse W, Jackson D, Montgomery R, Chupp G. Exploring the Effect of Anti-IL5 Therapy on Sputum Eosinophils in Children With Asthma. American Journal Of Respiratory And Critical Care Medicine 2022, 205: a4833-a4833. DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a4833.
- Ramirez M, Gupta A, Chupp G, Gomez J. Proteomic Characterization of Circulating Extracellular Vesicles in Adult Asthma. American Journal Of Respiratory And Critical Care Medicine 2022, 205: a3493-a3493. DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a3493.
- Jung E, Howell R, Cohen A, Tsang D, Chupp G, Dela Cruz C, Gautam S, Brewster R, Flint J, Yin H, Ristic N, Cosme C. Chemoattractant-Receptor Homologous Molecule on Th2 Cells (CRTH2) Regulates Neutrophilic Inflammation in the Lung. American Journal Of Respiratory And Critical Care Medicine 2022, 205: a2534-a2534. DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2534.
- Cao G, Lam H, Jude J, Karmacharya N, Kan M, Jester W, Koziol-White C, Himes B, Chupp G, An S, Panettieri R. Inhibition of ABCC1 Decreases cAMP Egress and Promotes Human Airway Smooth Muscle Cell Relaxation. American Journal Of Respiratory And Critical Care Medicine 2022, 205: a3280-a3280. DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a3280.
- Chupp G, Lee J, Liu M, Schleich F, Heaney L, Ribas C, Carrillo-Díaz T, Aparicio M, Moragón E, Sanchez-Herrero M, Gardiner F, Alfonso-Cristancho R, Jakes R, Price R, Howarth P. Mepolizumab Demonstrates Real-world Clinical Effectiveness in both Type 2 Biomarker High and Type 2 Biomarker Low Patients with Severe Asthma. The Journal Of Allergy And Clinical Immunology 2022, 149: ab318. DOI: 10.1016/j.jaci.2021.12.019.
- Chupp G, Alobid I, Lugogo N, Kariyawasam H, Bourdin A, Chaker A, Sousa A, Martin N, Yang S, Mayer B, Chan R, Matucci A, Chachuat L. Le mépolizumab réduit l’utilisation de corticostéroïdes systémiques chez les patients atteints de rhinosinusite chronique avec polypes nasaux. Revue Des Maladies Respiratoires Actualités 2022, 14: 34-35. DOI: 10.1016/j.rmra.2021.11.508.
- Steinfeld J, Gleich G, Roufosse F, Chupp G, Faguer S, Reiter A, Walz B, Bentley J, Bradford E, Yancey S, Picaud C. Tolérance et efficacité de mépolizumab dans le syndrome hyperéosinophilique : une étude d’extension en ouvert. La Revue De Médecine Interne 2021, 42: a411. DOI: 10.1016/j.revmed.2021.10.126.
- Oppenheimer J, Abott C, Chang S, Chupp G, Crawford J, Mannino D, Win P. D010 CAPTAIN STUDY: EFFECTS OF BASELINE IGE LEVELS ON TRIPLE THERAPY RESPONSE IN INADEQUATELY CONTROLLED ASTHMA. Annals Of Allergy Asthma & Immunology 2021, 127: s14. DOI: 10.1016/j.anai.2021.08.048.
- Israel E, Chupp G, Colice G, Cook B, Ambrose C, Roseti S, Hellqvist Å, Llanos-Ackert J. D011 TEZEPELUMAB EFFICACY ACCORDING TO US OMALIZUMAB ELIGIBILITY: RESULTS FROM THE NAVIGATOR PHASE 3 STUDY. Annals Of Allergy Asthma & Immunology 2021, 127: s14-s15. DOI: 10.1016/j.anai.2021.08.049.
- Chupp G, Menzies-Gow A, Ambrose C, Cook W, Kmita K, Lindsley A, Llanos-Ackert J, Colice G, Lugogo N. EFFICACY OF TEZEPELUMAB IN PATIENTS WITH SEVERE, UNCONTROLLED ASTHMA GROUPED BY BASELINE BMI IN THE NAVIGATOR STUDY. Chest 2021, 160: a37-a40. DOI: 10.1016/j.chest.2021.07.078.
- Chupp G, Feigler N, Gandhi H. VARIATIONS HIGHLIGHTED IN HYPERLOCAL HEATMAPS CAN ADDRESS UNMET NEED AND ALLOCATION OF RESOURCES IN COPD. Chest 2021, 160: a1796-a1797. DOI: 10.1016/j.chest.2021.07.1630.
- Kerstjens H, Abbott C, Boulet L, Chang S, Chupp G, Crawford J, Hanania N, Nathan R, Oppenheimer J, Pizzichini E, Sagara H, Busse W. CAPTAIN: Effects of triple therapy on FEV1 response in patients with inadequately controlled asthma on ICS/LABA. 2021, pa3386. DOI: 10.1183/13993003.congress-2021.pa3386.
- Israel E, Menzies-Gow A, Chupp G, Ambrose C, Cook B, Hunter G, Llanos-Ackert J, Downie J, Colice G. Efficacy of tezepelumab in adolescents with severe, uncontrolled asthma. 2021, oa1490. DOI: 10.1183/13993003.congress-2021.oa1490.
- Bourdin A, Menzies-Gow A, Chupp G, Ambrose C, Kmita K, Llanos-Ackert J, Colice G, Cook B. Effect of tezepelumab on exacerbation-related oral corticosteroid use in NAVIGATOR. 2021, oa1484. DOI: 10.1183/13993003.congress-2021.oa1484.
- Korn S, Bourdin A, Chupp G, Colice G, Ambrose C, Kmita K, Llanos-Ackert J, Molfino N, Cook B. Effect of tezepelumab on the proportion of exacerbation-free patients with severe, uncontrolled asthma in NAVIGATOR. 2021, oa1198. DOI: 10.1183/13993003.congress-2021.oa1198.
- Kay S, Chupp G, Gomez J. Sex-Specific Gene Expression in the Sputum of Patients with Asthma. American Journal Of Respiratory And Critical Care Medicine 2021, 203: a1383-a1383. DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1383.
- Chaudhuri R, Caruso C, Chupp G, Fera T, Koehler T, Schleich F, Valero A, Yang S, Howarth P, Jakes R, Maxwell A, Price R, Cristancho R. International Differences in the Use of Mepolizumab to Treat Severe Asthma – Impact of Reimbursement Policies. American Journal Of Respiratory And Critical Care Medicine 2021, 203: a1595-a1595. DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1595.
- Steinfeld J, Gleich G, Roufosse F, Chupp G, Faguer S, Reiter A, Walz B, Bentley J, Bradford E, Yancey S. Safety and Efficacy of Mepolizumab in Hypereosinophilic Syndrome: an Open-Label Extension Study. American Journal Of Respiratory And Critical Care Medicine 2021, 203: a1351-a1351. DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1351.
- Chupp G, Alobid I, Lugogo N, Kariyawasam H, Bourdin A, Chaker A, Sousa A, Martin N, Yang S, Mayer B, Chan R, Matucci A. Mepolizumab Reduces Systemic Corticosteroid Use in Patients with Chronic Rhinosinusitis with Nasal Polyps. American Journal Of Respiratory And Critical Care Medicine 2021, 203: a1344-a1344. DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1344.
- Bourdin A, Korn S, Chupp G, Cosio B, Arbetter D, Shah M, Gil E. Integrated Safety and Efficacy Among Patients with Severe Asthma Receiving Benralizumab for Up to Five Years. American Journal Of Respiratory And Critical Care Medicine 2021, 203: a1205-a1205. DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1205.
- Bourdin A, Menzies-Gow A, Chupp G, Israel E, Hellqvist, Hunter G, Ambrose C, Ackert J, Colice G, Cook B, Corren J. Reductions in Asthma Exacerbation-Related Hospitalizations and Emergency Department Visits in Patients with Severe, Uncontrolled Asthma Treated with Tezepelumab: Results from the Phase 3 NAVIGATOR Study. American Journal Of Respiratory And Critical Care Medicine 2021, 203: a1203-a1203. DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1203.
- Chupp G, Beeh K, Jauhiainen A, Necander S, Brown M, Hamrén U, Forsman H, Kurdyukova Y, Steele J, Astbury C, Psallidas I. Results of a Phase 2b Dose Finding Study of Velsecorat, an Inhaled Non-Steroidal, Selective Glucocorticoid Receptor Modulator in Asthma (GRANIT). American Journal Of Respiratory And Critical Care Medicine 2021, 203: a1202-a1202. DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1202.
- Corren J, Bourdin A, Chupp G, Israel E, Ambrose C, Ackert J, Kmita K, Cook B, Colice G, Menzies-Gow A. Efficacy of Tezepelumab in Patients with Severe, Uncontrolled Asthma Grouped by Baseline Blood Eosinophil Count and Fractional Exhaled Nitric Oxide Level: Results from the NAVIGATOR Phase 3 Study. American Journal Of Respiratory And Critical Care Medicine 2021, 203: a1198-a1198. DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1198.
- Menzies-Gow A, Corren J, Bourdin A, Chupp G, Israel E, Griffiths J, Hellqvist Å, Bowen K, Kaur P, Almqvist G, Ponnarambil S, Colice G. Efficacy and Safety of Tezepelumab in Adults and Adolescents with Severe, Uncontrolled Asthma: Results from the Phase 3 NAVIGATOR Study. The Journal Of Allergy And Clinical Immunology 2021, 147: ab249. DOI: 10.1016/j.jaci.2020.12.050.
- Chupp G, Kline J, Khatri S, McEvoy C, Shifren A, Bansal S, McClelland M, Dransfield M, Olivenstein R, Lawson E, Simoff M, Wahidi M, Lamb C, Ferguson J, Haas A, Hogarth D, Tejedor R, Laviolette M. LONG-TERM EFFICACY AND SAFETY OF BRONCHIAL THERMOPLASTY: 5-YEAR FOLLOW-UP RESULTS FROM A LARGE-SCALE PROSPECTIVE STUDY. Chest 2020, 158: a12-a16. DOI: 10.1016/j.chest.2020.08.059.
- Bleecker E, Murphy K, Gandhi H, Gilbert I, Zein J, Reibman J, Chupp G. Natural history of disease burden for US patients with asthma vs asthma and COPD. 2020, 1397. DOI: 10.1183/13993003.congress-2020.1397.
- Murphy K, Chipps B, Beuther D, Wise R, McCann W, Gilbert I, Eudicone J, Gandhi H, Harding G, Coyne K, Zeiger R, Board P, Kobernick A, Mohammad A, Cherry A, Fein A, Gaines A, Ramsey A, Michaud A, Palmer A, Kim A, Smith A, White A, Ricci A, Kettelhut B, Modena B, Stone B, Rolston B, Schnapf B, Krajicek B, Kraft C, Hopkins C, Natalie C, Anderson C, Czajkowski C, Arce D, Hamlin D, Hill D, Mares D, Pham D, Liao D, Simmons D, Johnson D, Jhaveri D, Maselli D, Kerwin E, Schuman E, Sher E, Bleecker E, Rakowski E, Hsu F, Averill F, Barsanti F, Gross G, Chupp G, Head G, Nasir H, Lee H, Barjaktarevic I, Cook J, Krainson J, Pearl J, Bellak J, Perez-Fernandez J, Rehm J, Trevor J, Most J, Hanson J, Blessing-Moore J, Biller J, Gedell J, Southard J, Chancellor J, Ilowite J, Romeo J, Mercado J, Fisher J, Greiwe J, Gregory K, Nadeau K, Shenoy K, Tan L, Stefanowicz L, Humes L, Bowers L, O’Connor M, Perez M, White M, Hegewald M, Wilson M, Sikora M, Morganroth M, Smith M, Farooqui N, Lesch N, Jain N, Parikh N, Hartog N, Luthin P, Stewart P, O’Connor P, Schochet P, Goldberg P, Patel P, Chinthrajah R, Sidhu R, Ayinla R, Brown R, Stadtler R, Wachs R, Balkissoon R, Duplantier R, Puente R, Settipane R, Mustafa S, Surani S, Jawad S, Adams S, Villegas S, Al-Farra S, Subramanian S, Bains S, Kelsen S, Wise S, Estrella-Eades S, Smith S, Qureshi T, Chen T, Kelbel T, Miller T, Jain V, Soong W, Soler X, Mattar Z. Development of the Asthma Impairment and Risk Questionnaire (AIRQ): A Composite Control Measure. The Journal Of Allergy And Clinical Immunology In Practice 2020, 8: 2263-2274.e5. PMID: 32387166, DOI: 10.1016/j.jaip.2020.02.042.
- Wang Z, Shan N, Yan X, Mane S, Gomez J, Chupp G. Whole Exome Sequencing of Severe Asthma Identifies Novel Gene Association Candidates. 2020, a1336-a1336. DOI: 10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a1336.
- Bleecker E, Murphy K, Gandhi H, Gilbert I, Chupp G. Assessing Asthma Control in the United States by Examining the Relationships Between Short-Acting Beta 2 -Agonist and Systemic Corticosteroid Use. 2020, a1818-a1818. DOI: 10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a1818.
- Koziol-White C, Parikh V, Chupp G, Panettieri R. Blocking YKL-40 (Chitinase-Like Protein Chitinase 3) Reverses IL-13/IL-4-Induced Hyporesponsiveness to Bronchodilators in Human Small Airways and in Human Airway Smooth Muscle Cells. 2020, a1252-a1252. DOI: 10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a1252.
- Glynn N, Gmelin T, Santanasto A, Lovato L, Lange‐Maia B, Nicklas B, Fielding R, Manini T, Myers V, Rekeneire N, Spring B, Pahor M, King A, Rejeski W, Newman A, Pahor M, Guralnik J, Anton S, Buford T, Leeuwenburgh C, Nayfield S, Manini T, Caudle C, Crump L, Holmes L, Lee J, Lu C, Miller M, Espeland M, Ambrosius W, Applegate W, Beavers D, Byington R, Cook D, Furberg C, Harvin L, Henkin L, Hepler J, Hsu F, Joyce K, Lovato L, Pierce J, Roberson W, Robertson J, Rushing J, Rushing S, Stowe C, Walkup M, Hire D, Rejeski W, Katula J, Brubaker P, Mihalko S, Jennings J, Chen S, Pierce J, Chen H, Hadley E, Romashkan S, Patel K, Bethesda, Bonds D, McDermott M, Spring B, Hauser J, Kerwin D, Domanchuk K, Graff R, Rego A, Church T, Blair S, Myers V, Monce R, Britt N, Harris M, McGucken A, Rodarte R, Millet H, Tudor‐Locke C, Butitta B, Donatto S, Cocreham S, King A, Castro C, Haskell W, Stafford R, Pruitt L, Yank V, Berra K, Bell C, Thiessen R, Youngman K, Virgen S, Maldonado E, Tarin K, Klaftenegger H, Prosak C, Campero I, Garcia D, Soto J, Chio L, Hoskins D, Fielding R, Nelson M, Folta S, Phillips E, Liu C, McDavitt E, Reid K, Kirn D, Pasha E, Kim W, Krol J, Beard V, Tsiroyannis E, Hau C, Manini T, Pahor M, Anton S, Buford T, Marsiske M, Nayfield S, Sandesara B, Black M, Burk W, Hoover B, Knaggs J, Marena W, Korytov I, Curtis S, Lorow M, Goswami C, Lewis M, Kamen M, Bitz J, Stanton B, Hicks T, Gay C, Xie C, Morris H, Singletary F, Causer J, Yonce S, Radcliff K, Smith M, Scott J, Rodriguez M, Fitch M, Dunn M, Schllesinger J, Newman A, Studenski S, Goodpaster B, Lopez O, Glynn N, Nadkarni N, Ives D, Newman M, Grove G, Williams K, Bonk J, Rush J, Kost P, Vincent P, Gerger A, Romeo J, Monheim L, Kritchevsky S, Marsh A, Brinkley T, Demons J, Sink K, Kennedy K, Shertzer‐Skinner R, Wrights A, Fries R, Barr D, Gill T, Axtell R, Kashaf S, Rekeneire N, McGloin J, Mautner R, Huie‐White S, Bianco L, Zocher J, Wu K, Shepard D, Fennelly B, Castro R, Halpin S, Brennan M, Barnett T, Iannone L, Zenoni M, Bugaj J, Bailey C, Charpentier P, Hawthorne‐Jones G, Mignosa B, Lewis L, Williamson J, Sink K, Hendrie H, Rapp S, Verghese J, Woolard N, Espeland M, Jennings J, Wilson V, Pepine C, Ariet M, Handberg E, Deluca D, Hill J, Szady A, Chupp G, Flynn G, Gill T, Hankinson J, Vaz Fragoso C, Groessl E, Kaplan R. Impact of Baseline Fatigue on a Physical Activity Intervention to Prevent Mobility Disability. Journal Of The American Geriatrics Society 2019, 68: 619-624. PMID: 31867713, PMCID: PMC8061638, DOI: 10.1111/jgs.16274.
- Mohan A, Grace J, Mainardi A, Chupp G, Lugogo N. Biomarkers, Targeted Therapies, Biologics, and Bronchial Thermoplasty. Respiratory Medicine 2019, 123-153. DOI: 10.1007/978-3-030-20812-7_8.
- Amick A, Liu Q, Gautam S, Chupp G, Dela Cruz C, Sharma L. Measurement of Chitinase Activity in Biological Samples. Journal Of Visualized Experiments 2019 DOI: 10.3791/60159-v.
- Stewart E, Chupp G, Montgomery R, Liu Q, Estrom J. Analysis of Sputum Immune Cell Populations and Their Functional Status in Asthmatics. 2019, a2916-a2916. DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2916.
- Gomez J, Chen A, Yan X, Cohn L, Chupp G. MicroRNA miR-223 Is Associated with Lung Function Impairment and TH17 Inflammation in Asthma. 2019, a2929-a2929. DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2929.
- Yan X, Liu Q, Mihaljinec A, Gomez J, Cohn L, Chupp G. Cell Lineage Defined by Single Cell Transcriptomics of the Sputum in Asthma. 2019, a6085-a6085. DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a6085.
- Chu J, Yan X, Liang A, Hu B, Gomez J, Chupp G. Integration of Sputum eQTL and GWAS Indicates IL-27/EBI3 Pathway Is Associated with Severe Asthma. 2019, a6088-a6088. DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a6088.
- Bleecker E, Murphy K, Gandhi H, Gilbert I, Chupp G. The Natural History of the Burden of Asthma in the United States by Age and Sex. 2019, a7397-a7397. DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7397.
- Chupp G, Kline J, Khatri S, McEvoy C, Silvestri G, Shifren A, Castro M, Bansal S, McClelland M, Dransfield M, Olivenstein R, Kahlstrom R, Ryan S, Lawson E, Simoff M, Wahidi M, Lamb C, Ferguson J, Haas A, Hogarth D, Tejedor R, Toth J, Majid A, Fitzgerald J, Enfield K, Grubb G, Laviolette M. Long-Term Efficacy and Safety of Bronchial Thermoplasty (BT): 4 Year Follow-Up Results from a Large Scale Prospective Study. 2019, a2683-a2683. DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2683.
- Chupp G, Brown M, Beeh K, Wahlby-Hamren U, Ekelund A, Barkstedt E, Forsman H, Björnsson E, Jauhiainen A, Steele J, Psallidas I. Design of a Phase 2b Dose Finding Study of AZD7594, an Inhaled Non-Steroidal, Selective Glucocorticoid Receptor Modulator, for the Treatment of Asthma. 2019, a1315-a1315. DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1315.
- Rapid onset of effect of benralizumab on morning peak expiratory flow in severe, uncontrolled asthmaChupp G, Lugogo N, Kline J, Ferguson G, Hirsch I, Goldman M, Zangrilli J, Trudo F. Rapid onset of effect of benralizumab on morning peak expiratory flow in severe, uncontrolled asthma. Annals Of Allergy Asthma & Immunology 2019, 122: 478-485. PMID: 30802500, DOI: 10.1016/j.anai.2019.02.016.
- Busse W, Chupp G, Nagase H, Albers F, Doyle S, Shen Q, Bratton D, Gunsoy N. Anti–IL-5 treatments in patients with severe asthma by blood eosinophil thresholds: Indirect treatment comparison. The Journal Of Allergy And Clinical Immunology 2018, 143: 190-200.e20. PMID: 30205189, DOI: 10.1016/j.jaci.2018.08.031.
- Chupp G, Ferguson G, Hirsch I, Goldman M, Zangrilli J, Trudo F. Benralizumab Treatment Produces Rapid Changes in Morning Peak Expiratory Flow in Patients With Severe, Uncontrolled Eosinophilic Asthma. The Journal Of Allergy And Clinical Immunology 2018, 141: ab15. DOI: 10.1016/j.jaci.2017.12.046.
- Corbett DB, Rejeski WJ, Tudor-Locke C, Glynn NW, Kritchevsky SB, McDermott MM, Church TS, Fielding RA, Gill TM, King AC, Miller ME, Chen H, Pahor M, Manini TM, Pahor M, Guralnik J, Leeuwenburgh C, Caudle C, Crump L, Holmes L, Lee J, Lu C, Salem W, Miller M, Espeland M, Ambrosius W, Applegate W, Beavers D, Byington R, Cook D, Furberg C, Harvin L, Henkin L, Hepler J, Hsu F, Lovato L, Roberson W, Rushing J, Rushing S, Stowe C, Walkup M, Hire D, Rejeski W, Katula J, Brubaker P, Mihalko S, Jennings J, Hadley E, Romashkan S, Patel K, Bonds D, McDermott M, Hauser J, Kerwin D, Domanchuk K, Graff R, Rego A, Church T, Blair S, Myers V, Monce R, Britt N, Harris M, McGucken A, Rodarte R, Millet H, Tudor-Locke C, Butitta B, Donatto S, Cocreham S, King A, Castro C, Haskell W, Stafford R, Pruitt L, Berra K, Yank V, Fielding R, Nelson M, Folta S, Phillips E, Liu C, McDavitt E, Reid K, Kim W, Beard V, Manini T, Pahor M, Anton S, Buford T, Marsiske M, Sandesara B, Knaggs J, Lorow M, Marena W, Korytov I, Morris H, Fitch M, Singletary F, Causer J, Radcliff K, Newman A, Studenski S, Goodpaster B, Glynn N, Lopez O, Nadkarni N, Williams K, Newman M, Grove G, Bonk J, Rush J, Kost P, Ives D, Kritchevsky S, Marsh A, Brinkley T, Demons J, Sink K, Kennedy K, Shertzer-Skinner R, Wrights A, Fries R, Barr D, Gill T, Axtell R, Kashaf S, de Rekeneire N, McGloin J, Wu K, Shepard D, Fennelly B, Iannone L, Mautner R, Barnett T, Halpin S, Brennan M, Bugaj J, Zenoni M, Mignosa B, Williamson J, Sink K, Hendrie H, Rapp S, Verghese J, Woolard N, Espeland M, Jennings J, Pepine C, Ariet M, Handberg E, Deluca D, Hill J, Szady A, Chupp G, Flynn G, Gill T, Hankinson J, Fragoso C, Groessl E, Kaplan R. Social Participation Modifies the Effect of a Structured Physical Activity Program on Major Mobility Disability Among Older Adults: Results From the LIFE Study. The Journals Of Gerontology Series B 2017, 73: 1501-1513. PMID: 28482106, PMCID: PMC6178963, DOI: 10.1093/geronb/gbx051.
- Trevor J, Bradford E, Albers F, Bratton D, Wang-Jairaj J, Nelsen L, Chupp G, Magnan A, Brinke A. Mepolizumab Improves Lung Function and Exacerbation Rates in Severe Eosinophilic Asthma: The Musca Study - a Phase IIIb Randomized, Placebo-Controlled Tria. The Journal Of Allergy And Clinical Immunology 2017, 139: ab380. DOI: 10.1016/j.jaci.2016.12.912.
- Chupp G, Bradford E, Albers F, Bratton D, Wang-Jairaj J, Nelsen L, Trevor J, Magnan A, Brinke A. Mepolizumab Significantly Improves Health Status and Asthma Control in Severe Eosinophilic Asthma: The Musca Study - a Phase IIIb Randomized, Placebo-Controlled Trial. The Journal Of Allergy And Clinical Immunology 2017, 139: ab380. DOI: 10.1016/j.jaci.2016.12.911.
- Yao Y, Welp T, Liu Q, Niu N, Wang X, Britto CJ, Krishnaswamy S, Chupp G, Montgomery RR. Multiparameter Single Cell Profiling of Airway Inflammatory Cells. Cytometry Part B Clinical Cytometry 2017, 92: 12-20. PMID: 27807928, PMCID: PMC5250532, DOI: 10.1002/cyto.b.21491.
- Silkoff P, Laviolette M, Singh D, FitzGerald J, Kelsen S, Backer V, Porsbjerg C, Girodet P, Berger P, Kline J, Chupp G, Susulic V, Barnathan E, Baribaud F, Loza M, investigators A, Strambu I, Lam S, Eich A, Ludwig-Sengpiel A, Leigh R, Dransfield M, Calhoun W, Hussaini A, Chanez P. Identification of airway mucosal type 2 inflammation by using clinical biomarkers in asthmatic patients. The Journal Of Allergy And Clinical Immunology 2017, 140: 710-719. PMID: 28089872, DOI: 10.1016/j.jaci.2016.11.038.
- Aubertin-Leheudre M, Anton S, Beavers D, Manini T, Fielding R, Newman A, Church T, Kritchevsky S, Conroy D, McDermott M, Botoseneanu A, Hauser M, Pahor M, Gill T, Fragoso C, Fielding R, Hauser M, Pahor M, Guralnik J, Leeuwenburgh C, Caudle C, Crump L, Holmes L, Lee J, Lu C, Miller M, Espeland M, Ambrosius W, Applegate W, Beavers D, Byington R, Cook D, Furberg C, Harvin L, Henkin L, Hepler M, Hsu F, Lovato L, Roberson W, Rushing J, Rushing S, Stowe C, Walkup M, Hire D, Rejeski W, Katula J, Brubaker P, Mihalko S, Jennings J, Hadley E, Romashkan S, Patel K, Bonds D, McDermott M, Spring B, Hauser J, Kerwin D, Domanchuk K, Graff R, Rego A, Church T, Blair S, Myers V, Monce R, Britt N, Harris M, McGucken A, Rodarte R, Millet H, Tudor-Locke C, Butitta B, Donatto S, Cocreham S, King A, Castro C, Haskell W, Stafford R, Pruitt L, Berra K, Yank V, Fielding R, Nelson M, Folta S, Phillips E, Liu C, McDavitt E, Reid K, Kirn D, Pasha E, Kim W, Beard V, Tsiroyannis E, Hau C, Manini T, Pahor M, Anton S, Nayfield S, Buford T, Marsiske M, Sandesara B, Knaggs J, Lorow M, Marena W, Korytov I, Morris H, Fitch M, Singletary F, Causer J, Radcliff K, Newman A, Studenski S, Goodpaster B, Glynn N, Lopez O, Nadkarni N, Williams K, Newman M, Grove G, Bonk J, Rush J, Kost P, Ives D, Kritchevsky S, Marsh A, Brinkley T, Demons J, Sink K, Kennedy K, Shertzer-Skinner R, Wrights A, Fries R, Barr D, Gill T, Axtell R, Kashaf S, de Rekeneire N, McGloin J, Wu K, Shepard D, Fennelly B, Iannone L, Mautner R, Barnett T, Halpin S, Brennan M, Bugaj J, Zenoni M, Mignosa B, Williamson J, Sink K, Hendrie H, Rapp S, Verghese J, Woolard N, Espeland M, Jennings J, Wilson V, Pepine C, Ariet M, Handberg E, Deluca D, Hill J, Szady A, Chupp G, Flynn G, Gill T, Hankinson J, Fragoso C, Groessl E, Kaplan R. Dynapenia and Metabolic Health in Obese and Nonobese Adults Aged 70 Years and Older: The LIFE Study. Journal Of The American Medical Directors Association 2016, 18: 312-319. PMID: 27914851, PMCID: PMC5366275, DOI: 10.1016/j.jamda.2016.10.001.
- Baldassarri S, Chupp G, Leone F, Warren G, Toll B. Chest Health-care Provider Perceptions of Electronic Cigarettes. Chest 2016, 150: 1302a. DOI: 10.1016/j.chest.2016.08.1417.
- Chupp G, Yan X, Nezgovorova V, Grant N, Bradford W, Brophy C, Cohn L. MAPKAP kinase 2(MK2) expression is associated with severe asthma. 2016, pa4649. DOI: 10.1183/13993003.congress-2016.pa4649.
- Gueble M, Holm C, Grant N, Ravage-Mass L, Levesh T, Estrom J, Kapagiannidou E, Liu Q, O'Connor P, Gomez-Villalobos J, Cohn L, Chupp G. Proinflammatory cytokines and IP-10 differentiate neutrophilic and eosinophilic asthma subgroups. 2016, pa908. DOI: 10.1183/13993003.congress-2016.pa908.
- Layne AS, Hsu FC, Blair SN, Chen SH, Dungan J, Fielding RA, Glynn NW, Hajduk AM, King AC, Manini TM, Marsh AP, Pahor M, Pellegrini CA, Buford TW, Investigators L, Pahor M, Guralnik J, Leeuwenburgh C, Caudle C, Crump L, Holmes L, Lee J, Lu C, Miller M, Espeland M, Ambrosius W, Applegate W, Beavers D, Byington R, Cook D, Furberg C, Harvin L, Henkin L, Hepler J, Hsu F, Lovato L, Roberson W, Rushing J, Rushing S, Stowe C, Walkup M, Hire D, Rejeski W, Katula J, Brubaker P, Mihalko S, Jennings J, Hadley E, Romashkan S, Patel K, Bonds D, McDermott M, Spring B, Hauser J, Kerwin D, Domanchuk K, Graff R, Rego A, Church T, Blair S, Myers V, Monce R, Britt N, Harris M, McGucken A, Rodarte R, Millet H, Tudor-Locke C, Butitta B, Donatto S, Cocreham S, King A, Castro C, Haskell W, Stafford R, Pruitt L, Berra K, Yank V, Fielding R, Nelson M, Folta S, Phillips E, Liu C, McDavitt E, Reid K, Kim W, Beard V, Manini T, Pahor M, Anton S, Nayfield S, Buford T, Marsiske M, Sandesara B, Knaggs J, Lorow M, Marena W, Korytov I, Morris H, Fitch M, Singletary F, Causer J, Radcliff K, Newman A, Studenski S, Goodpaster B, Glynn N, Lopez O, Nadkarni N, Williams K, Newman M, Grove G, Bonk J, Rush J, Kost P, Ives D, Kritchevsky S, Marsh A, Brinkley T, Demons J, Sink K, Kennedy K, Shertzer-Skinner R, Wrights A, Fries R, Barr D, Gill T, Axtell R, Kashaf S, de Rekeneire N, McGloin J, Wu K, Shepard D, Fennelly B, Iannone L, Mautner R, Barnett T, Halpin S, Brennan M, Bugaj J, Zenoni M, Mignosa B, Williamson J, Sink K, Hendrie H, Rapp S, Verghese J, Woolard N, Espeland M, Jennings J, Pepine C, Ariet M, Handberg E, Deluca D, Hill J, Szady A, Chupp G, Flynn G, Gill T, Hankinson J, Fragoso C, Groessl E, Kaplan R. Predictors of Change in Physical Function in Older Adults in Response to Long-Term, Structured Physical Activity: The LIFE Study. Archives Of Physical Medicine And Rehabilitation 2016, 98: 11-24.e3. PMID: 27568165, PMCID: PMC5183463, DOI: 10.1016/j.apmr.2016.07.019.
- Baker M, Steinke J, Borish L, Chupp G. Leukotriene C4 Synthase Expression in Sputum Correlates with Disease Severity Amongst Patients with Different Clinical Phenotypes of Asthma. The Journal Of Allergy And Clinical Immunology 2016, 137: ab207. DOI: 10.1016/j.jaci.2015.12.1118.
- Ortega H, Chupp G, Bardin P, Bourdin A, Garcia G, Hartley B, Yancey S, Humbert M. The role of mepolizumab in atopic and nonatopic severe asthma with persistent eosinophilia. European Respiratory Journal 2014, 44: 239-241. PMID: 24659543, DOI: 10.1183/09031936.00220413.
- Baldassarri S, Chupp G. A 43-Year-Old Man With Intravenous Drug Abuse and Recurrent Endocarditis. Chest 2013, 144: 296a-296b. DOI: 10.1378/chest.1676394.
- Loza M, Strambu I, Laviolette M, Singh D, Fitzgerald J, Kelsen S, Eich A, Ludwig-Sengpiel A, Chupp G, Porsbjerg C, Berger P, Leigh R, Kline J, Dransfield M, Calhoun W, Hussaini A, Chanez P, Susulic V, Silkoff P, Baribaud F. ADEPT, airway disease endotyping for personalized treatment: Interim analysis of asthma patients. European Respiratory Journal 2013, 42: p748. DOI: 10.1183/13993003/erj.42.suppl_57.p748.
- Scatena R, Holm C, He S, Wright P, Sessa W, Cohn L, Gomez-Villalobos J, Mitchell A, Chupp G. Characterization Of The Poor Emotional Function Phenotype In Asthma. 2012, a3967-a3967. DOI: 10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a3967.
- Fielding RA, Rejeski WJ, Blair S, Church T, Espeland MA, Gill TM, Guralnik JM, Hsu FC, Katula J, King AC, Kritchevsky SB, McDermott MM, Miller ME, Nayfield S, Newman AB, Williamson JD, Bonds D, Romashkan S, Hadley E, Pahor M. The Lifestyle Interventions and Independence for Elders Study: Design and Methods. The Journals Of Gerontology Series A 2011, 66A: 1226-1237. PMID: 21825283, PMCID: PMC3193523, DOI: 10.1093/gerona/glr123.
- Pathways Activated during Human Asthma Exacerbation as Revealed by Gene Expression Patterns in BloodBjornsdottir US, Holgate ST, Reddy PS, Hill AA, McKee CM, Csimma CI, Weaver AA, Legault HM, Small CG, Ramsey RC, Ellis DK, Burke CM, Thompson PJ, Howarth PH, Wardlaw AJ, Bardin PG, Bernstein DI, Irving LB, Chupp GL, Bensch GW, Bensch GW, Stahlman JE, Karetzky M, Baker JW, Miller RL, Goodman BH, Raible DG, Goldman SJ, Miller DK, Ryan JL, Dorner AJ, Immermann FW, O'Toole M. Pathways Activated during Human Asthma Exacerbation as Revealed by Gene Expression Patterns in Blood. PLOS ONE 2011, 6: e21902. PMID: 21779351, PMCID: PMC3136489, DOI: 10.1371/journal.pone.0021902.
- Ramaprakash H, Shibata T, Duffy KE, Ismailoglu UB, Bredernitz RM, Moreira AP, Coelho AL, Das AM, Fursov N, Chupp GL, Hogaboam CM. Targeting ST2L Potentiates CpG-Mediated Therapeutic Effects in a Chronic Fungal Asthma Model. American Journal Of Pathology 2011, 179: 104-115. PMID: 21640974, PMCID: PMC3123853, DOI: 10.1016/j.ajpath.2011.03.032.
- Gomez J, Perez M, Mitchell A, Holm C, He S, Chupp G. Airway Macrophage Expression Signatures Associated With Severe Airflow Obstruction In Asthma. 2011, a4540-a4540. DOI: 10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a4540.
- Scatena R, Chupp G, Perez M, Gomez J, Wright P, Sessa W, Holm C. The Role Of Neurite Outgrowth Inhibitory Protein-B In Poorly Controlled Asthma. 2011, a1349-a1349. DOI: 10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a1349.
- Perez M, Gomez J, He S, Holm C, Chupp G. Characterization Of Chitinase Activity In Patients With Stable Asthma. 2011, a4334-a4334. DOI: 10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a4334.
- Ong P, Wisnewski A, Stowe M, Holm C, He X, Zheng W, Zhang C, Zhao H, Redlich C, Chupp G. The 24-bp CHIT1 Exon 10 Polymorphism Is Associated With Airway Hyperresponsiveness In A Population Of Autobody Shop Workers. 2010, a4002-a4002. DOI: 10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a4002.
- Gomez J, Perez M, He X, Mitchell A, Holm C, Chupp G. Characterization Of Chitinase Activity And YKL-40 Expression In Induced Sputum From Asthmatics: Correlations With Inflammation And Cell Viability And Gene Expression. 2010, a4279-a4279. DOI: 10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a4279.
- Perez M, Gomez J, He X, Mitchell A, Kelly E, Jarjour N, Chupp G. Correlations Between The Chitinase-Like Protein YKL-40 And IL-18 After Segmental Antigen Challenge. 2010, a5605-a5605. DOI: 10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a5605.
- Marshall P, Possick J, Chupp G. Intensive Care Unit Management of Status Asthmaticus. Clinical Pulmonary Medicine 2009, 16: 293-301. DOI: 10.1097/cpm.0b013e3181bdff38.
- Ober C, Chupp GL. The chitinase and chitinase-like proteins: a review of genetic and functional studies in asthma and immune-mediated diseases. Current Opinion In Allergy And Clinical Immunology 2009, 9: 401-408. PMID: 19644363, PMCID: PMC3018778, DOI: 10.1097/aci.0b013e3283306533.
- Crisafi G, Chupp G, Evans M, Sorkness R, Swenson C, Busse W, Jarjour N. Chitotriosidase Activity and YKL-40 Protein Are Increased in Severe Asthma. 2009, a5440. DOI: 10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a5440.
- Vicencio A, Tsirilakis K, Du Z, Zeng W, Kipperman S, Veler H, Chupp G, Goldman D. Chitinase Activity and YKL-40 Expression in Lungs of Children with Persistent Asthma. 2009, a4811. DOI: 10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a4811.
- O'Toole M, Bjornsdottir U, Holgate S, Reddy P, Hill A, McKee C, Csimma C, Legault H, Weaver A, Small C, Ramsey R, Ellis D, Burke C, Thompson P, Irving L, Enden J, Chupp G, Wardlaw A, Stahlman J, Raible D, Miller D, Goldman S, Ryan J, Dorner A, Immermann F. Biological Mechanism Associated with Asthma Exacerbation Attack as Revealed By Gene Expression Patterns of Peripheral Blood Mononuclear Cells. The Journal Of Allergy And Clinical Immunology 2009, 123: s154. DOI: 10.1016/j.jaci.2008.12.576.
- Ober C, Tan Z, Sun Y, Possick JD, Pan L, Nicolae R, Radford S, Parry RR, Heinzmann A, Deichmann KA, Lester LA, Gern JE, Lemanske RF, Nicolae DL, Elias JA, Chupp GL. Effect of Variation in CHI3L1 on Serum YKL-40 Level, Risk of Asthma, and Lung Function. The New England Journal Of Medicine 2008, 358: 1682-1691. PMID: 18403759, PMCID: PMC2629486, DOI: 10.1056/nejmoa0708801.
- Chupp GL, Lee CG, Jarjour N, Shim YM, Holm CT, He S, Dziura JD, Reed J, Coyle AJ, Kiener P, Cullen M, Grandsaigne M, Dombret MC, Aubier M, Pretolani M, Elias JA. A Chitinase-like Protein in the Lung and Circulation of Patients with Severe Asthma. The New England Journal Of Medicine 2007, 357: 2016-2027. PMID: 18003958, DOI: 10.1056/nejmoa073600.
- Bhandari V, Choo-Wing R, Lee CG, Zhu Z, Nedrelow JH, Chupp GL, Zhang X, Matthay MA, Ware LB, Homer RJ, Lee PJ, Geick A, de Fougerolles AR, Elias JA. Hyperoxia causes angiopoietin 2–mediated acute lung injury and necrotic cell death. Nature Medicine 2006, 12: 1286-1293. PMID: 17086189, PMCID: PMC2768268, DOI: 10.1038/nm1494.
- Khazeni N, Homer RJ, Rubinowitz AN, Chupp GL. Massive cavitary pulmonary rheumatoid nodules in a patient with HIV. European Respiratory Journal 2006, 28: 872-874. PMID: 17012633, DOI: 10.1183/09031936.06.00144105.
- Lee CG, Kang HR, Homer RJ, Chupp G, Elias JA. Transgenic Modeling of Transforming Growth Factor-β1. Annals Of The American Thoracic Society 2006, 3: 418-423. PMID: 16799085, PMCID: PMC2658706, DOI: 10.1513/pats.200602-017aw.
- Sabina AB, Williams A, Wall HK, Bansal S, Chupp G, Katz DL. Yoga intervention for adults with mild-to-moderate asthma: a pilot study. Annals Of Allergy Asthma & Immunology 2005, 94: 543-548. PMID: 15945557, DOI: 10.1016/s1081-1206(10)61131-3.
- Cohn L, Elias JA, Chupp GL. Asthma: Mechanisms of Disease Persistence and Progression. Annual Review Of Immunology 2004, 22: 789-815. PMID: 15032597, DOI: 10.1146/annurev.immunol.22.012703.104716.
- CHUPP G. PREFACE. Clinics In Chest Medicine 2001, 22: xi. DOI: 10.1016/s0272-5231(05)70054-x.
- O'Regan A, Nau G, Chupp G, Berman J. Osteopontin (Eta-1) in cell-mediated immunity: teaching an old dog new tricks. Trends In Immunology 2000, 21: 475-478. PMID: 11071524, DOI: 10.1016/s0167-5699(00)01715-1.
- Corne J, Chupp G, Lee C, Homer R, Zhu Z, Chen Q, Ma B, Du Y, Roux F, McArdle J, Waxman A, Elias J. IL-13 stimulates vascular endothelial cell growth factor and protects against hyperoxic acute lung injury. Journal Of Clinical Investigation 2000, 106: 783-791. PMID: 10995789, PMCID: PMC381393, DOI: 10.1172/jci9674.
- Nau G, Chupp G, Emile J, Jouanguy E, Berman J, Casanova J, Young R. Osteopontin Expression Correlates with Clinical Outcome in Patients with Mycobacterial Infection. American Journal Of Pathology 2000, 157: 37-42. PMID: 10880373, PMCID: PMC1850209, DOI: 10.1016/s0002-9440(10)64514-2.
- Elias J, Zhu Z, Chupp G, Homer R. Airway remodeling in asthma. Journal Of Clinical Investigation 1999, 104: 1001-1006. PMID: 10525034, PMCID: PMC408860, DOI: 10.1172/jci8124.
- Nau G, Liaw L, Chupp G, Berman J, Hogan B, Young R. Attenuated Host Resistance againstMycobacterium bovis BCG Infection in Mice Lacking Osteopontin. Infection And Immunity 1999, 67: 4223-4230. PMID: 10417195, PMCID: PMC96728, DOI: 10.1128/iai.67.8.4223-4230.1999.
- Nau G, Guilfoile P, Chupp G, Berman J, Kim S, Kornfeld H, Young R. A chemoattractant cytokine associated with granulomas in tuberculosis and silicosis. Proceedings Of The National Academy Of Sciences Of The United States Of America 1997, 94: 6414-6419. PMID: 9177232, PMCID: PMC21064, DOI: 10.1073/pnas.94.12.6414.
- Cruikshank W, Kornfeld H, Berman J, Chupp G, Keane J, Center D. Biological activity of interleukin-16. Nature 1996, 382: 501-502. PMID: 8700223, DOI: 10.1038/382501b0.
- Winchester Center for Lung DiseaseFitkin Memorial Pavilion789 Howard Avenue, Ste 2nd floorNew Haven, CT 06519
- Winchester Center for Lung DiseaseNorth Haven Medical Center6 Devine StreetNorth Haven, CT 06473
- Winchester Center for Lung DiseaseFitkin Memorial Pavilion789 Howard Avenue, Ste 2nd floorNew Haven, CT 06519
- Winchester Center for Lung DiseaseNorth Haven Medical Center6 Devine StreetNorth Haven, CT 06473