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  • Yale New Haven Hospital
    20 York Street
    New Haven, CT 06510

Erol Fikrig, MD, BA

Internal Medicine, Infectious Diseases
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Patient type treated
Adult
Accepting new patients
No
Referral required
Not Applicable
Board Certified in
Internal Medicine

Biography

My laboratory investigates vector-borne diseases. Studies are directed toward understanding Lyme disease, Human granulocytic ehrlichiosis, and West Nile virus. Efforts on Lyme disease include exploring immunity to Borrelia burgdorferi, selective B. burgdorferi gene expression in vivo, and the immunobiology of Lyme arthritis. Human granulocytic ehrlichiosis is caused by a newly described pathogen, transmitted by Ixodes scapularis ticks, that persists within neutrophils. We are investigating the molecular strategies that this pathogen uses to survive in polymorphonuclear leukocytes. West Nile virus can cause fatal encephalitis, and we seek to understand the pathogenesis of this emerging disease. Finally, we are also developing molecular approaches to prevent ticks from feeding on a mammalian host, thereby interfering with pathogen transmission.

Titles

  • Waldemar Von Zedtwitz Professor of Medicine (Infectious Diseases) and Professor of Epidemiology (Microbial Diseases) and of Microbial Pathogenesis
  • Section Chief, Infectious Diseases

Education & Training

  • MD
    Cornell University (1985)
  • BA
    Cornell University (1981)
  • Resident
    Vanderbilt University Hospital
  • Fellow
    Yale University School of Medicine

Additional Information

Biography

My laboratory investigates vector-borne diseases. Studies are directed toward understanding Lyme disease, Human granulocytic ehrlichiosis, and West Nile virus. Efforts on Lyme disease include exploring immunity to Borrelia burgdorferi, selective B. burgdorferi gene expression in vivo, and the immunobiology of Lyme arthritis. Human granulocytic ehrlichiosis is caused by a newly described pathogen, transmitted by Ixodes scapularis ticks, that persists within neutrophils. We are investigating the molecular strategies that this pathogen uses to survive in polymorphonuclear leukocytes. West Nile virus can cause fatal encephalitis, and we seek to understand the pathogenesis of this emerging disease. Finally, we are also developing molecular approaches to prevent ticks from feeding on a mammalian host, thereby interfering with pathogen transmission.

Titles

  • Waldemar Von Zedtwitz Professor of Medicine (Infectious Diseases) and Professor of Epidemiology (Microbial Diseases) and of Microbial Pathogenesis
  • Section Chief, Infectious Diseases

Education & Training

  • MD
    Cornell University (1985)
  • BA
    Cornell University (1981)
  • Resident
    Vanderbilt University Hospital
  • Fellow
    Yale University School of Medicine

Additional Information

  • Yale New Haven Hospital
    20 York Street
    New Haven, CT 06510