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Clinical Trials

Discover the future of medicine today. Yale Medicine currently offers 693 active clinical trials across our hospitals and care centers, providing our patients with early access to many of the world’s most advanced therapies. Yale Center for Clinical Investigation (YCCI) supports, coordinates, and oversees clinical trials, ensuring the safety of trial volunteers.

For more information about cancer-related trials, call us at 203-785-5702. For all other trials, call 877-978-8343.

What is a Clinical Trial?
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11 Results

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Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis (CAPTIVA)
- Brain, Spinal Cord & Nervous System
- Gender:All Genders
- Age:30 years - 80 years
PRIMROSE: A Modular Phase I/IIa, Multi-centre, Dose Escalation, and Expansion Study of AZD3470, a MTA Cooperative PRMT5 Inhibitor, as Monotherapy and in Combination With Anticancer Agents in Patients With Advanced/Metastatic Solid Tumours That Are MTAP Deficient
- Phase 1 Cancers
Safety and Efficacy Study of reSept ASD Occluder for Treating Secundum ASD (ASCENT ASD)
- Heart/Cardiovascular
- Genetics
- Gender:All Genders
- Age:84 years and younger
CABA-201 for Systemic Sclerosis
- Orthopaedics, Muscle & Bone
- Gender:All Genders
- Age:18 years - 70 years
Short TeRm Intensified Pembrolizumab (KEytruda) and Tivozanib for High-Risk Renal Cell Carcinoma - STRIKE
- Kidney Cancer
A Phase II Trial to Improve Safety of Capivasertib for HR+/HER2- Metastatic Breast Cancer
- Breast Cancer
A Phase 1, First-in-Human Study of CUSP06, a Cadherin-6 (CDH6)-Directed Antibody-Drug Conjugate, in Patients With Platinum-Refractory/Resistant Ovarian Cancer and Other Advanced Solid Tumors
- Phase 1 Cancers
A Phase 3, Randomized, Open-label Study of MK-5684 Versus Alternative Abiraterone Acetate or Enzalutamide in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) That Progressed On or After Prior Treatment With One Next-generation Hormonal Agent (NHA)
- Prostate Cancer
Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)
- Prostate Cancer
Datopotamab Deruxtecan and Trastuzumab Deruxtecan for the Treatment of HER2-Negative Unresectable, Locally Advanced or Metastatic Breast Cancer
- Breast Cancer

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