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Clinical Trials

Discover the future of medicine today. Yale Medicine currently offers 689 active clinical trials across our hospitals and care centers, providing our patients with early access to many of the world’s most advanced therapies. Yale Center for Clinical Investigation (YCCI) supports, coordinates, and oversees clinical trials, ensuring the safety of trial volunteers.

For more information about cancer-related trials, call us at 203-785-5702. For all other trials, call 877-978-8343.

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For healthy volunteers(7)

41 Results

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A Phase 1, Dose Escalation, and Cohort Expansion Study Evaluating NX-5948, a Bruton's Tyrosine Kinase (BTK) Degrader, in Adults With Relapsed/Refractory B-cell Malignancies
- Brain and Other Nervous System Cancers
- Leukemia
- Lymphoma
- Gender:All Genders
- Age:18 years and older
A Phase 1/2 Study of REGN5678 (Anti-PSMAxCD28) With Cemiplimab (Anti-PD-1) in Patients With Metastatic Castration-resistant Prostate Cancer
- Prostate Cancer
A Phase 2 Randomized, Multicenter Study to Evaluate the Efficacy and Safety of Silevertinib, an Oral EGFR Inhibitor, in Combination With Temozolomide in Patients With Newly Diagnosed Glioblastoma With Unmethylated MGMT Promoter and EGFRvIII
- Brain and Other Nervous System Cancers
A Phase 2, Multicenter, Clinical Study to Evaluate the Efficacy and Safety of Safusidenib Erbumine in Patients With Isocitrate Dehydrogenase 1 (IDH1) Mutant Glioma
- Brain and Other Nervous System Cancers
A Phase 2, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Intrathecally Administered ALN-APP in Patients with Cerebral Amyloid Angiopathy (CAA)
- Heart/Cardiovascular
- Gender:All Genders
- Age:30 years and older
A prospective study to evaluate the use of the Minder device to aid in developing a treatment plan after inconclusive prolonged EEG in patients with epilepsy.
Anticoagulation for Stroke Prevention and Recovery After ICH (ASPIRE)
- Heart/Cardiovascular
- Brain, Spinal Cord & Nervous System
- Gender:All Genders
- Age:18 years and older
Are you are currently experiencing brain fog from Long COVID?
- COVID-19 Outpatient
Brain Emotion Circuitry-Targeted Self-Monitoring and Regulation Therapy (BE-SMART)
- Brain, Spinal Cord & Nervous System
- Genetics
- Mental Health & Behavioral Research
- Gender:All Genders
- Age:16 years - 24 years
Brain Imaging Study of Affect and Learning
- Mental Health & Behavioral Research

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