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Phase Pilot

Effects of High Intensity Interval Training Among Patients With Prostate Cancer Prior to Radical Prostatectomy

  • Study IRB#:2000041449
  • Last Updated:08/17/2026

This pilot study will explore the metabolic and psychological effects of High-Intensity Interval Training (HIIT) exercise as well as its impact on patient recovery from radical prostatectomy.

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    Trial Purpose and Description

    Participants will have a minimum of fourteen study visits.

    Eligibility Criteria

    Inclusion Criteria:

    • Scheduled or intended treatment with radical prostatectomy at Yale New Haven Hospital
    • English language fluency
    • Clinically localized low, intermediate or high risk by National Comprehensive Cancer Network (NCCN) criteria
    • Able to attend 2 in person exercise training sessions per week for four-six weeks

    Exclusion Criteria:

    • Treatment with non-surgical modality
    • Prior therapy for prostate cancer (e.g. radiation therapy or focal therapy)
    • Already engaged in regular exercise (>60 minutes per week)
    • Unstable cardiovascular disease
    • Physical mobility limitation, unable to walk or exercise
    • Locally advanced (cT4 or cN1 or cM1) prostate cancer
    • Prior treatment with androgen deprivation therapy

    Principal Investigator

    Sub-Investigators

    For more information about this study, including how to volunteer, contact: