Peter D Block, MD, MSc
Hepatology, Gastroenterology, Transplant Hepatology
Next Available Appointment
Call the Care center at 1-877-YALEMDS (1-877-925-3637)
Titles
- Assistant Professor
Education & Training
- Transplant Hepatology FellowNYU Langone Health (2025)
- Gastroenterology & Hepatology FellowYale School of Medicine (2024)
- Resident PhysicianThomas Jefferson University Hospitals (2021)
- MDSidney Kimmel Medical College at Thomas Jefferson University, Medicine (2018)
- MScOxford University, Immunology (2013)
- BAHaverford College, Philosophy (2011)
Additional Information
Board Certifications
- AB of Internal Medicine, Gastroenterology (2024)
- AB of Internal Medicine, Internal Medicine (2021)
Professional Service
- AASLD Hepatitis B Special Interest Group (2025 - Present): Steering Committee member
- Hepatitis B Foundation Emerging Scholars Committee (2022 - Present): Steering Committee member
Publications
- Block SJ, Block PD, Graham CS, Sulkowski M, Wang S, Tu T, Cohen C. Sexual health and young people living with chronic hepatitis B: adopting a treatment as prevention framework. Lancet Gastroenterol Hepatol 2025, 10: 609-612. PMID: 40482651, DOI: 10.1016/S2468-1253(25)00123-2.
- Block PD, Lim JK. Unmet needs in the clinical management of chronic hepatitis B infection. J Formos Med Assoc 2025, 124: 502-507. PMID: 39155176, DOI: 10.1016/j.jfma.2024.08.020.
- Block P, Assis D. Hepatotoxicity of Chemotherapy and Immune Checkpoint Inhibitors. Clinics In Liver Disease 2025, 29: 483-501. PMID: 40670034, DOI: 10.1016/j.cld.2025.03.006.
- Block TM, Guo JT, Zoulim F, Rice CM, Thio CL, Schneider WM, Alter HJ, Jacobson IM, Gish RG, Block PD, Sulkowski M, Feld JJ, Cohen CA. New potent HBV replication inhibitors for the management of chronic hepatitis B are needed. Nat Rev Gastroenterol Hepatol 2025, 22: 150-151. PMID: 39910374, DOI: 10.1038/s41575-025-01037-z.
- Block P, Strazzabosco M, Jaffe A. Approach to immunotherapy for HCC in the liver transplant population. Clinical Liver Disease 2024, 23: e0158. PMID: 38707244, PMCID: PMC11068135, DOI: 10.1097/cld.0000000000000158.
- Block PD, Farrell JJ, Li DK. A Rare Cause of Gastrointestinal Bleeding After Pancreaticoduodenectomy. Gastroenterology 2023, 165: 34-36. PMID: 36592728, DOI: 10.1053/j.gastro.2022.12.022.
- Block PD, Lim JK. Chronic Hepatitis B Virus: What an Internist Needs to Know: Serologic Diagnosis, Treatment Options, and Hepatitis B Virus Reactivation. Med Clin North Am 2023, 107: 435-447. PMID: 37001946, DOI: 10.1016/j.mcna.2022.12.002.
- Lin SY, Halegoua-DeMarzio D, Block P, Kao YL, Civan J, Shieh FS, Song W, Hann HW, Su YH. Persistently Elevated HBV Viral-Host Junction DNA in Urine as a Biomarker for Hepatocellular Carcinoma Minimum Residual Disease and Recurrence: A Pilot Study. Diagnostics (Basel) 2023, 13 PMID: 37174929, DOI: 10.3390/diagnostics13091537.
- Li CJ, Claxton BB, Block P, Reilly S, Manski S, Choudhary C. Acute Esophageal Necrosis Secondary to a Paraesophageal Hernia. Case Rep Gastroenterol 2021, 15: 594-597. PMID: 34616261, DOI: 10.1159/000517235.
- Block PD, Shinn B, Kim JH, Hann HW. Hepatitis B-related hepatocellular carcinoma and stress: untangling the host immune response from clinical outcomes. Hepat Oncol 2020, 8: HEP35. PMID: 33680431, DOI: 10.2217/hep-2020-0028.
- Xia Y, Carpentier A, Cheng X, Block PD, Zhao Y, Zhang Z, Protzer U, Liang TJ. Human stem cell-derived hepatocytes as a model for hepatitis B virus infection, spreading and virus-host interactions. J Hepatol 2017, 66: 494-503. PMID: 27746336, DOI: 10.1016/j.jhep.2016.10.009.
- Muthumani K, Block P, Flingai S, Muruganantham N, Chaaithanya IK, Tingey C, Wise M, Reuschel EL, Chung C, Muthumani A, Sarangan G, Srikanth P, Khan AS, Vijayachari P, Sardesai NY, Kim JJ, Ugen KE, Weiner DB. Rapid and Long-Term Immunity Elicited by DNA-Encoded Antibody Prophylaxis and DNA Vaccination Against Chikungunya Virus. J Infect Dis 2016, 214: 369-78. PMID: 27001960, DOI: 10.1093/infdis/jiw111.
- Ternette N, Block PD, Sánchez-Bernabéu Á, Borthwick N, Pappalardo E, Abdul-Jawad S, Ondondo B, Charles PD, Dorrell L, Kessler BM, Hanke T. Early Kinetics of the HLA Class I-Associated Peptidome of MVA.HIVconsv-Infected Cells. J Virol 2015, 89: 5760-71. PMID: 25810538, DOI: 10.1128/JVI.03627-14.
- Sinnathamby G, Zerfass J, Hafner J, Block P, Nickens Z, Hobeika A, Secord AA, Lyerly HK, Morse MA, Philip R. ADAM metallopeptidase domain 17 (ADAM17) is naturally processed through major histocompatibility complex (MHC) class I molecules and is a potential immunotherapeutic target in breast, ovarian and prostate cancers. Clin Exp Immunol 2011, 163: 324-32. PMID: 21175594, DOI: 10.1111/j.1365-2249.2010.04298.x.
Departments and Programs
Titles
- Assistant Professor
Education & Training
- Transplant Hepatology FellowNYU Langone Health (2025)
- Gastroenterology & Hepatology FellowYale School of Medicine (2024)
- Resident PhysicianThomas Jefferson University Hospitals (2021)
- MDSidney Kimmel Medical College at Thomas Jefferson University, Medicine (2018)
- MScOxford University, Immunology (2013)
- BAHaverford College, Philosophy (2011)
Additional Information
Board Certifications
- AB of Internal Medicine, Gastroenterology (2024)
- AB of Internal Medicine, Internal Medicine (2021)
Professional Service
- AASLD Hepatitis B Special Interest Group (2025 - Present): Steering Committee member
- Hepatitis B Foundation Emerging Scholars Committee (2022 - Present): Steering Committee member
Publications
- Block SJ, Block PD, Graham CS, Sulkowski M, Wang S, Tu T, Cohen C. Sexual health and young people living with chronic hepatitis B: adopting a treatment as prevention framework. Lancet Gastroenterol Hepatol 2025, 10: 609-612. PMID: 40482651, DOI: 10.1016/S2468-1253(25)00123-2.
- Block PD, Lim JK. Unmet needs in the clinical management of chronic hepatitis B infection. J Formos Med Assoc 2025, 124: 502-507. PMID: 39155176, DOI: 10.1016/j.jfma.2024.08.020.
- Block P, Assis D. Hepatotoxicity of Chemotherapy and Immune Checkpoint Inhibitors. Clinics In Liver Disease 2025, 29: 483-501. PMID: 40670034, DOI: 10.1016/j.cld.2025.03.006.
- Block TM, Guo JT, Zoulim F, Rice CM, Thio CL, Schneider WM, Alter HJ, Jacobson IM, Gish RG, Block PD, Sulkowski M, Feld JJ, Cohen CA. New potent HBV replication inhibitors for the management of chronic hepatitis B are needed. Nat Rev Gastroenterol Hepatol 2025, 22: 150-151. PMID: 39910374, DOI: 10.1038/s41575-025-01037-z.
- Block P, Strazzabosco M, Jaffe A. Approach to immunotherapy for HCC in the liver transplant population. Clinical Liver Disease 2024, 23: e0158. PMID: 38707244, PMCID: PMC11068135, DOI: 10.1097/cld.0000000000000158.
- Block PD, Farrell JJ, Li DK. A Rare Cause of Gastrointestinal Bleeding After Pancreaticoduodenectomy. Gastroenterology 2023, 165: 34-36. PMID: 36592728, DOI: 10.1053/j.gastro.2022.12.022.
- Block PD, Lim JK. Chronic Hepatitis B Virus: What an Internist Needs to Know: Serologic Diagnosis, Treatment Options, and Hepatitis B Virus Reactivation. Med Clin North Am 2023, 107: 435-447. PMID: 37001946, DOI: 10.1016/j.mcna.2022.12.002.
- Lin SY, Halegoua-DeMarzio D, Block P, Kao YL, Civan J, Shieh FS, Song W, Hann HW, Su YH. Persistently Elevated HBV Viral-Host Junction DNA in Urine as a Biomarker for Hepatocellular Carcinoma Minimum Residual Disease and Recurrence: A Pilot Study. Diagnostics (Basel) 2023, 13 PMID: 37174929, DOI: 10.3390/diagnostics13091537.
- Li CJ, Claxton BB, Block P, Reilly S, Manski S, Choudhary C. Acute Esophageal Necrosis Secondary to a Paraesophageal Hernia. Case Rep Gastroenterol 2021, 15: 594-597. PMID: 34616261, DOI: 10.1159/000517235.
- Block PD, Shinn B, Kim JH, Hann HW. Hepatitis B-related hepatocellular carcinoma and stress: untangling the host immune response from clinical outcomes. Hepat Oncol 2020, 8: HEP35. PMID: 33680431, DOI: 10.2217/hep-2020-0028.
- Xia Y, Carpentier A, Cheng X, Block PD, Zhao Y, Zhang Z, Protzer U, Liang TJ. Human stem cell-derived hepatocytes as a model for hepatitis B virus infection, spreading and virus-host interactions. J Hepatol 2017, 66: 494-503. PMID: 27746336, DOI: 10.1016/j.jhep.2016.10.009.
- Muthumani K, Block P, Flingai S, Muruganantham N, Chaaithanya IK, Tingey C, Wise M, Reuschel EL, Chung C, Muthumani A, Sarangan G, Srikanth P, Khan AS, Vijayachari P, Sardesai NY, Kim JJ, Ugen KE, Weiner DB. Rapid and Long-Term Immunity Elicited by DNA-Encoded Antibody Prophylaxis and DNA Vaccination Against Chikungunya Virus. J Infect Dis 2016, 214: 369-78. PMID: 27001960, DOI: 10.1093/infdis/jiw111.
- Ternette N, Block PD, Sánchez-Bernabéu Á, Borthwick N, Pappalardo E, Abdul-Jawad S, Ondondo B, Charles PD, Dorrell L, Kessler BM, Hanke T. Early Kinetics of the HLA Class I-Associated Peptidome of MVA.HIVconsv-Infected Cells. J Virol 2015, 89: 5760-71. PMID: 25810538, DOI: 10.1128/JVI.03627-14.
- Sinnathamby G, Zerfass J, Hafner J, Block P, Nickens Z, Hobeika A, Secord AA, Lyerly HK, Morse MA, Philip R. ADAM metallopeptidase domain 17 (ADAM17) is naturally processed through major histocompatibility complex (MHC) class I molecules and is a potential immunotherapeutic target in breast, ovarian and prostate cancers. Clin Exp Immunol 2011, 163: 324-32. PMID: 21175594, DOI: 10.1111/j.1365-2249.2010.04298.x.
Departments and Programs