Mahalia S. Desruisseaux, MD

Infectious Diseases, Internal Medicine

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Click here to view more about this specialist's research and educational efforts on https://medicine.yale.edu

Click here to view more about this specialist's research and educational efforts onhttps://medicine.yale.edu

Titles

Associate Professor of Internal Medicine (Infectious Diseases)
Affiliated Faculty, Yale Institute for Global Health

Education & Training

Research Fellow, Neuroscience
Albert Einstein College of Medicine (2008)
Fellow, Infectious Diseases
Albert Einstein College of Medicine/ Montefiore Medical Center (2007)
Resident, Internal Medicine
North Shore University Hospital - Hofstra/Northwell (2003)
MD
Rutgers Robert Wood Johnson Medical School
BA
Queens College - City University of New York

Languages Spoken

Kreyòl (Creole)
English
Français (French)

Additional Information

Honors & Recognitions

Professional Service

Publications

Endothelins in inflammatory neurological diseases.
D'Orléans-Juste P, Akide Ndunge OB, Desbiens L, Tanowitz HB, Desruisseaux MS. Endothelins in inflammatory neurological diseases. Pharmacology & Therapeutics 2019, 194: 145-160. PMID: 30291906, PMCID: PMC6348026, DOI: 10.1016/j.pharmthera.2018.10.001.
Trypanosoma cruzi Produces the Specialized Proresolving Mediators Resolvin D1, Resolvin D5, and Resolvin E2.
Colas RA, Ashton AW, Mukherjee S, Dalli J, Akide-Ndunge OB, Huang H, Desruisseaux MS, Guan F, Jelicks LA, Matos Dos Santos F, Nagajyothi J, Zingman MA, Reyes J, Weiss LM, Serhan CN, Tanowitz HB. Trypanosoma cruzi Produces the Specialized Proresolving Mediators Resolvin D1, Resolvin D5, and Resolvin E2. Infection And Immunity 2018, 86 PMID: 29358332, PMCID: PMC5865043, DOI: 10.1128/IAI.00688-17.
Endothelin-1 Mediates Brain Microvascular Dysfunction Leading to Long-Term Cognitive Impairment in a Model of Experimental Cerebral Malaria.
Freeman BD, Martins YC, Akide-Ndunge OB, Bruno FP, Wang H, Tanowitz HB, Spray DC, Desruisseaux MS. Endothelin-1 Mediates Brain Microvascular Dysfunction Leading to Long-Term Cognitive Impairment in a Model of Experimental Cerebral Malaria. PLoS Pathogens 2016, 12: e1005477. PMID: 27031954, PMCID: PMC4816336, DOI: 10.1371/journal.ppat.1005477.
Endothelin-1 Treatment Induces an Experimental Cerebral Malaria-Like Syndrome in C57BL/6 Mice Infected with Plasmodium berghei NK65.
Martins YC, Freeman BD, Akide Ndunge OB, Weiss LM, Tanowitz HB, Desruisseaux MS. Endothelin-1 Treatment Induces an Experimental Cerebral Malaria-Like Syndrome in C57BL/6 Mice Infected with Plasmodium berghei NK65. The American Journal Of Pathology 2016, 186: 2957-2969. PMID: 27640146, PMCID: PMC5222963, DOI: 10.1016/j.ajpath.2016.07.020.
Altered regulation of Akt signaling with murine cerebral malaria, effects on long-term neuro-cognitive function, restoration with lithium treatment.
Dai M, Freeman B, Shikani HJ, Bruno FP, Collado JE, Macias R, Reznik SE, Davies P, Spray DC, Tanowitz HB, Weiss LM, Desruisseaux MS. Altered regulation of Akt signaling with murine cerebral malaria, effects on long-term neuro-cognitive function, restoration with lithium treatment. PloS One 2012, 7: e44117. PMID: 23082110, PMCID: PMC3474787, DOI: 10.1371/journal.pone.0044117.
Response of adipose tissue to early infection with Trypanosoma cruzi (Brazil strain).
Nagajyothi F, Desruisseaux MS, Machado FS, Upadhya R, Zhao D, Schwartz GJ, Teixeira MM, Albanese C, Lisanti MP, Chua SC, Weiss LM, Scherer PE, Tanowitz HB. Response of adipose tissue to early infection with Trypanosoma cruzi (Brazil strain). The Journal Of Infectious Diseases 2012, 205: 830-40. PMID: 22293433, PMCID: PMC3274374, DOI: 10.1093/infdis/jir840.

Patient Care Organizations

View Academic Profile

Click here to view more about this specialist's research and educational efforts on https://medicine.yale.edu

Click here to view more about this specialist's research and educational efforts onhttps://medicine.yale.edu

Titles

Associate Professor of Internal Medicine (Infectious Diseases)
Affiliated Faculty, Yale Institute for Global Health

Education & Training

Research Fellow, Neuroscience
Albert Einstein College of Medicine (2008)
Fellow, Infectious Diseases
Albert Einstein College of Medicine/ Montefiore Medical Center (2007)
Resident, Internal Medicine
North Shore University Hospital - Hofstra/Northwell (2003)
MD
Rutgers Robert Wood Johnson Medical School
BA
Queens College - City University of New York

Languages Spoken

Kreyòl (Creole)
English
Français (French)

Additional Information

Honors & Recognitions

Professional Service

Publications

Endothelins in inflammatory neurological diseases.
D'Orléans-Juste P, Akide Ndunge OB, Desbiens L, Tanowitz HB, Desruisseaux MS. Endothelins in inflammatory neurological diseases. Pharmacology & Therapeutics 2019, 194: 145-160. PMID: 30291906, PMCID: PMC6348026, DOI: 10.1016/j.pharmthera.2018.10.001.
Trypanosoma cruzi Produces the Specialized Proresolving Mediators Resolvin D1, Resolvin D5, and Resolvin E2.
Colas RA, Ashton AW, Mukherjee S, Dalli J, Akide-Ndunge OB, Huang H, Desruisseaux MS, Guan F, Jelicks LA, Matos Dos Santos F, Nagajyothi J, Zingman MA, Reyes J, Weiss LM, Serhan CN, Tanowitz HB. Trypanosoma cruzi Produces the Specialized Proresolving Mediators Resolvin D1, Resolvin D5, and Resolvin E2. Infection And Immunity 2018, 86 PMID: 29358332, PMCID: PMC5865043, DOI: 10.1128/IAI.00688-17.
Endothelin-1 Mediates Brain Microvascular Dysfunction Leading to Long-Term Cognitive Impairment in a Model of Experimental Cerebral Malaria.
Freeman BD, Martins YC, Akide-Ndunge OB, Bruno FP, Wang H, Tanowitz HB, Spray DC, Desruisseaux MS. Endothelin-1 Mediates Brain Microvascular Dysfunction Leading to Long-Term Cognitive Impairment in a Model of Experimental Cerebral Malaria. PLoS Pathogens 2016, 12: e1005477. PMID: 27031954, PMCID: PMC4816336, DOI: 10.1371/journal.ppat.1005477.
Endothelin-1 Treatment Induces an Experimental Cerebral Malaria-Like Syndrome in C57BL/6 Mice Infected with Plasmodium berghei NK65.
Martins YC, Freeman BD, Akide Ndunge OB, Weiss LM, Tanowitz HB, Desruisseaux MS. Endothelin-1 Treatment Induces an Experimental Cerebral Malaria-Like Syndrome in C57BL/6 Mice Infected with Plasmodium berghei NK65. The American Journal Of Pathology 2016, 186: 2957-2969. PMID: 27640146, PMCID: PMC5222963, DOI: 10.1016/j.ajpath.2016.07.020.
Altered regulation of Akt signaling with murine cerebral malaria, effects on long-term neuro-cognitive function, restoration with lithium treatment.
Dai M, Freeman B, Shikani HJ, Bruno FP, Collado JE, Macias R, Reznik SE, Davies P, Spray DC, Tanowitz HB, Weiss LM, Desruisseaux MS. Altered regulation of Akt signaling with murine cerebral malaria, effects on long-term neuro-cognitive function, restoration with lithium treatment. PloS One 2012, 7: e44117. PMID: 23082110, PMCID: PMC3474787, DOI: 10.1371/journal.pone.0044117.
Response of adipose tissue to early infection with Trypanosoma cruzi (Brazil strain).
Nagajyothi F, Desruisseaux MS, Machado FS, Upadhya R, Zhao D, Schwartz GJ, Teixeira MM, Albanese C, Lisanti MP, Chua SC, Weiss LM, Scherer PE, Tanowitz HB. Response of adipose tissue to early infection with Trypanosoma cruzi (Brazil strain). The Journal Of Infectious Diseases 2012, 205: 830-40. PMID: 22293433, PMCID: PMC3274374, DOI: 10.1093/infdis/jir840.

Patient Care Organizations