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Jeffrey Testani, MD, MTR

Cardiovascular Medicine, Heart Failure
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Patient type treated
Accepting new patients
Referral required
Not Applicable
Board Certified in
Cardiovascular Disease


My clinical training is as an advanced heart failure and cardiac transplantation physician with formal research training in patient oriented translational research. My research program is supported by NIH and investigator-initiated industry sources and uses techniques of both translational and clinical research to further the mechanistic understanding of cardiac-renal interactions, fluid and sodium homeostasis, and diuretic resistance in heart failure. The primary approach of my current research program is prospective mechanistic human studies in hospitalized heart failure patients, for which we have established extensive infrastructure.  Notably, we have enrolled over 700 patients and conducted over 1300 intense biospecimen collections resulting in the over 500,000 biospecimens currently housed in our biorepository at Yale. My lab has extensive expertise in biomarker research has established and maintains an extensive bioassay resource with the capability to determine an extensive range of analytes in human biological samples with complexity ranging from simple serum chemistries to complex analytes such as ultra-trace lithium by inductively coupled plasma mass spectrometry, deuterium concentration by nuclear magnetic resonance, high dimension multiplex protein assays, and large and small molecules by liquid chromatography mass spectrometry. 


  • Associate Professor of Medicine
  • Director of Heart Failure Research, Cardiovascular Medicine
  • Co-Director Heart & Vascular Center Clinical Research, Heart & Vascular Center

Education & Training

  • Fellowship
    Hospital of the University of Pennsylvania (2012)
  • MS
    University of Pennsylvania Medical School (2012)
  • Research Fellowship
    Hospital of the University of Pennsylvania (2011)
  • Fellowship
    Hospital of the University of Pennsylvania (2009)
  • Residency
    Hospital of the University of Pennsylvania (2007)
  • Internship
    Hospital of the University of Pennsylvania (2005)
  • MD
    University of Florida (2004)

Additional Information

  • Yale Heart and Vascular Center - YPB2
    Yale Physicians Building
    800 Howard Avenue, Fl 2nd
    New Haven, CT, 06519
  • Yale Cardiology
    175 Sherman Avenue
    Ste 2nd Floor
    New Haven, CT, 06511