Evangelos K. Oikonomou, MD, DPhil
Cardiovascular Medicine
Biography
Evangelos K. Oikonomou, MD, DPhil, is a cardiovascular medicine specialist who focuses on the diagnosis and management of heart and blood vessel diseases. He provides advanced care for a wide range of cardiovascular conditions, using both state-of-the-art imaging techniques and data-driven approaches to personalize patient assessment and treatment.
“I strive to build long-term relationships with my patients and emphasize the prevention of cardiovascular disease,” Dr. Oikonomou says. “I believe every patient is unique. In my practice, I listen carefully and work collaboratively to develop personalized treatment plans grounded in the best available evidence. Helping individuals take proactive steps to preserve their heart health is one of the most rewarding aspects of my work.”
As a clinical fellow in cardiovascular medicine at Yale School of Medicine, Dr. Oikonomou’s research bridges medicine and data science with the goal of enhancing how heart disease is detected and managed. He develops artificial intelligence tools that help identify heart disease patterns from imaging tests such as echocardiograms and cardiac CT scans. These methods improve the detection of both common and rare cardiac conditions and support more accurate risk assessment. Dr. Oikonomou also investigates how inflammation in the tissues surrounding blood vessels affects heart health and works to create tools that guide more tailored treatments for patients. His research includes the use of computer vision and machine learning methods to find personalized responses to therapies, which can make clinical trials more efficient and patient care more precise.
Dr. Oikonomou is widely published in top journals and has received notable awards from the American Heart Association, American College of Cardiology, European Society of Cardiology and American Society for Clinical Investigation, as well as the Radcliffe Department of Medicine Graduate Prize from the University of Oxford. “Cardiology brings together a unique blend of acute and chronic care, across all ages and disease spectrums,” Dr. Oikonomou says. “I was drawn to the intellectual rigor of integrating history, physical examination, and imaging diagnostics to make precise diagnoses, and to a field that continuously evolves through impactful clinical trials and innovation.”
He received his medical degree from the University of Athens Medical School in Greece, completed doctoral studies in medical sciences at the University of Oxford in the United Kingdom, and his residency, as well as clinical and post-doctoral research fellowship in cardiovascular medicine at Yale School of Medicine.
Titles
- Assistant Professor
Education & Training
- Post-doctoral fellowYale School of Medicine (2025)
- Clinical fellowYale School of Medicine (2025)
- ResidentYale School of Medicine (2021)
- InternYale School of Medicine (2020)
- DPhilUniversity of Oxford (2020)
- MDUniversity of Athens School of Health Sciences (2015)
Languages Spoken
- English
- Ελληνικά (Greek)
Additional Information
Honors & Recognitions
- Wiesman Award for Excellence in Early Career ATTR Research: ATTR Early- Career Research Forum (2025)
- Robert A. Winn Excellence in Clinical Trials Career Development Award: VCU Massey Comprehensive Cancer Center (2025)
- Heart Tank For the Cardiovascular Investigator - Imaging (Winner): American College of Cardiology (ACC) (2024)
- Trainee Poster Award Winner: CERSI Summit 2024 (2024)
- ASCI emerging generation (e-Gen) award: American Society of Clinical Investigation (ASCI) (2024)
- Elizabeth Barrett-Connor Research Award in Epidemiology and Prevention (Winner): American Heart Association (2023)
- Ruth L. Kirschstein Postdoctoral Individual National Research Service Award (F32): National Heart, Lung, and Blood Institute (NIH) (2023)
- Yale/Mayo CERSI scholar 2022-2023: Yale University & Mayo Clinic Center for Excellence in Regulatory Science and Innovation (CERSI) (2022)
- Council on Lifestyle and Cardiometabolic Health Early Career Investigator Award: American Heart Association (2021)
- First Place Award (Clinical Fellows): Northwestern Cardiovascular Young Investigators' Forum (2021)
Board Certifications
- AB of Internal Medicine, Internal Medicine (2022)
Professional Service
- European Heart Journal (2024 - Present): Associate Editor
Publications
- Holste G, Oikonomou E, Tokodi M, Kovács A, Wang Z, Khera R. Complete AI-Enabled Echocardiography Interpretation With Multitask Deep Learning. JAMA: The Journal Of The American Medical Association 2025, 334: 306-318. PMID: 40549400, PMCID: PMC12186137, DOI: 10.1001/jama.2025.8731.
- Oikonomou E, Sangha V, Shankar S, Coppi A, Krumholz H, Nasir K, Miller E, Gallegos Kattan C, Al-Mallah M, Al-Kindi S, Khera R. Artificial intelligence-enabled electrocardiography and echocardiography to track preclinical progression of transthyretin amyloid cardiomyopathy. European Heart Journal 2025, 46: 3651-3662. PMID: 40679604, PMCID: PMC12488324, DOI: 10.1093/eurheartj/ehaf450.
- Oikonomou E, Sangha V, Dhingra L, Aminorroaya A, Coppi A, Krumholz H, Baldassarre L, Khera R. Artificial Intelligence–Enhanced Risk Stratification of Cancer Therapeutics–Related Cardiac Dysfunction Using Electrocardiographic Images. Circulation Cardiovascular Quality And Outcomes 2024, 18: e011504. PMID: 39221857, PMCID: PMC11745701, DOI: 10.1161/circoutcomes.124.011504.
- Oikonomou E, Vaid A, Holste G, Coppi A, McNamara R, Baloescu C, Krumholz H, Wang Z, Apakama D, Nadkarni G, Khera R. Artificial intelligence-guided detection of under-recognised cardiomyopathies on point-of-care cardiac ultrasonography: a multicentre study. The Lancet Digital Health 2025, 7: e113-e123. PMID: 39890242, PMCID: PMC12084816, DOI: 10.1016/s2589-7500(24)00249-8.
- Oikonomou E, Khera R. Artificial intelligence-enhanced patient evaluation: bridging art and science. European Heart Journal 2024, 45: 3204-3218. PMID: 38976371, PMCID: PMC11400875, DOI: 10.1093/eurheartj/ehae415.
- Khera R, Oikonomou E, Nadkarni G, Morley J, Wiens J, Butte A, Topol E. Transforming Cardiovascular Care With Artificial Intelligence: From Discovery to Practice JACC State-of-the-Art Review. Journal Of The American College Of Cardiology 2024, 84: 97-114. PMID: 38925729, PMCID: PMC12204085, DOI: 10.1016/j.jacc.2024.05.003.
- Oikonomou E, Holste G, Yuan N, Coppi A, McNamara R, Haynes N, Vora A, Velazquez E, Li F, Menon V, Kapadia S, Gill T, Nadkarni G, Krumholz H, Wang Z, Ouyang D, Khera R. A Multimodal Video-Based AI Biomarker for Aortic Stenosis Development and Progression. JAMA Cardiology 2024, 9: 534-544. PMID: 38581644, PMCID: PMC10999005, DOI: 10.1001/jamacardio.2024.0595.
- Oikonomou E, Thangaraj P, Bhatt D, Ross J, Young L, Krumholz H, Suchard M, Khera R. An explainable machine learning-based phenomapping strategy for adaptive predictive enrichment in randomized clinical trials. Npj Digital Medicine 2023, 6: 217. PMID: 38001154, PMCID: PMC10673945, DOI: 10.1038/s41746-023-00963-z.
- Holste G, Oikonomou E, Mortazavi B, Coppi A, Faridi K, Miller E, Forrest J, McNamara R, Ohno-Machado L, Yuan N, Gupta A, Ouyang D, Krumholz H, Wang Z, Khera R. Severe aortic stenosis detection by deep learning applied to echocardiography. European Heart Journal 2023, 44: 4592-4604. PMID: 37611002, PMCID: PMC11004929, DOI: 10.1093/eurheartj/ehad456.
- Oikonomou EK, Spatz ES, Suchard MA, Khera R. Individualising intensive systolic blood pressure reduction in hypertension using computational trial phenomaps and machine learning: a post-hoc analysis of randomised clinical trials. The Lancet Digital Health 2022, 4: e796-e805. PMID: 36307193, PMCID: PMC9768739, DOI: 10.1016/s2589-7500(22)00170-4.
- Oikonomou EK, Van Dijk D, Parise H, Suchard MA, de Lemos J, Antoniades C, Velazquez EJ, Miller EJ, Khera R. A phenomapping-derived tool to personalize the selection of anatomical vs. functional testing in evaluating chest pain (ASSIST). European Heart Journal 2021, 42: 2536-2548. PMID: 33881513, PMCID: PMC8488385, DOI: 10.1093/eurheartj/ehab223.
- Oikonomou EK, Desai MY, Marwan M, Kotanidis CP, Antonopoulos AS, Schottlander D, Channon KM, Neubauer S, Achenbach S, Antoniades C. Perivascular Fat Attenuation Index Stratifies Cardiac Risk Associated With High-Risk Plaques in the CRISP-CT Study. Journal Of The American College Of Cardiology 2020, 76: 755-757. PMID: 32762910, DOI: 10.1016/j.jacc.2020.05.078.
- Oikonomou EK, Williams MC, Kotanidis CP, Desai MY, Marwan M, Antonopoulos AS, Thomas KE, Thomas S, Akoumianakis I, Fan LM, Kesavan S, Herdman L, Alashi A, Centeno EH, Lyasheva M, Griffin BP, Flamm SD, Shirodaria C, Sabharwal N, Kelion A, Dweck MR, Van Beek EJR, Deanfield J, Hopewell JC, Neubauer S, Channon KM, Achenbach S, Newby DE, Antoniades C. A novel machine learning-derived radiotranscriptomic signature of perivascular fat improves cardiac risk prediction using coronary CT angiography. European Heart Journal 2019, 40: 3529-3543. PMID: 31504423, PMCID: PMC6855141, DOI: 10.1093/eurheartj/ehz592.
- Oikonomou EK, Antoniades C. The role of adipose tissue in cardiovascular health and disease. Nature Reviews Cardiology 2018, 16: 83-99. PMID: 30287946, DOI: 10.1038/s41569-018-0097-6.
- Oikonomou EK, Marwan M, Desai MY, Mancio J, Alashi A, Centeno E, Thomas S, Herdman L, Kotanidis CP, Thomas KE, Griffin BP, Flamm SD, Antonopoulos AS, Shirodaria C, Sabharwal N, Deanfield J, Neubauer S, Hopewell JC, Channon KM, Achenbach S, Antoniades C. Non-invasive detection of coronary inflammation using computed tomography and prediction of residual cardiovascular risk (the CRISP CT study): a post-hoc analysis of prospective outcome data. The Lancet 2018, 392: 929-939. PMID: 30170852, PMCID: PMC6137540, DOI: 10.1016/s0140-6736(18)31114-0.
- Holste G, Oikonomou EK, Khera R. AI-Enabled Echocardiography Interpretation With Multitask Deep Learning-Reply. JAMA 2025, 334: 1954-1955. PMID: 41160035, DOI: 10.1001/jama.2025.16627.
- Dhingra LS, Croon PM, Batinica B, Aminorroaya A, Pedroso AF, Oikonomou EK, Khera R. Reliability of Artificial Intelligence-enhanced Electrocardiography. MedRxiv 2025 PMID: 41282699, DOI: 10.1101/2025.11.04.25339526.
- Croon P, Dhingra L, Biswas D, Oikonomou E, Khera R. Phenotypic Selectivity of Artificial Intelligence–Enhanced Electrocardiography in Cardiovascular Diagnosis and Risk Prediction. Circulation 2025, 152: 1282-1294. PMID: 40888124, PMCID: PMC12573264, DOI: 10.1161/circulationaha.125.076279.
- Kagiyama N, Tokodi M, Hathaway QA, Arnaout R, Davies R, Dey D, Duchateau N, Fraser AG, Goto S, Jamthikar AD, Lam CSP, Oikonomou EK, Ouyang D, Pandey A, Poterucha TJ, Raisi-Estabragh Z, Strom JB, Zhang Q, Yanamala N, Sengupta PP. PRIME 2.0: Proposed Requirements for Cardiovascular Imaging-Related Multimodal-AI Evaluation: An Updated Checklist. JACC Cardiovasc Imaging 2025 PMID: 40892627, DOI: 10.1016/j.jcmg.2025.08.004.
- Duffy G, Oikonomou E, Easton N, Usuku H, Patel J, Katsumata Y, Yamasawa D, Stern L, Goto S, Tsujita K, Cheng P, Khera R, Ahmad F, Ouyang D. International Validation of Echocardiographic Artificial Intelligence Amyloid Detection Algorithm. JACC Advances 2025, 102067. PMID: 40965401, DOI: 10.1016/j.jacadv.2025.102067.
- Oikonomou E, Khera R. Artificial intelligence-guided point-of-care ultrasonography for cardiomyopathy detection – Authors' reply. The Lancet Digital Health 2025, 7: 100893. PMID: 40769793, DOI: 10.1016/j.landig.2025.100893.
- Sangha V, Dhingra L, Aminorroaya A, Croon P, Sikand N, Sen S, Martinez M, Maron M, Krumholz H, Asselbergs F, Oikonomou E, Khera R. Identification of hypertrophic cardiomyopathy on electrocardiographic images with deep learning. Nature Cardiovascular Research 2025, 4: 991-1000. PMID: 40696040, DOI: 10.1038/s44161-025-00685-3.
- Artificial Intelligence–Enabled Prediction of Heart Failure Risk From Single-Lead ElectrocardiogramsDhingra L, Aminorroaya A, Pedroso A, Khunte A, Sangha V, McIntyre D, Chow C, Asselbergs F, Brant L, Barreto S, Ribeiro A, Krumholz H, Oikonomou E, Khera R. Artificial Intelligence–Enabled Prediction of Heart Failure Risk From Single-Lead Electrocardiograms. JAMA Cardiology 2025, 10: 574-584. PMID: 40238120, PMCID: PMC12004248, DOI: 10.1001/jamacardio.2025.0492.
- From Pixels to Patterns: Radiomic Subphenotyping of Left Ventricular Hypertrophy on EchocardiographyOikonomou E, Khera R. From Pixels to Patterns: Radiomic Subphenotyping of Left Ventricular Hypertrophy on Echocardiography. Circulation Cardiovascular Imaging 2025, 18: e018291. PMID: 40326361, DOI: 10.1161/circimaging.125.018291.
- Thangaraj P, Oikonomou E, Dhingra L, Aminorroaya A, Jayaram R, Suchard M, Khera R. Computational Phenomapping of Randomized Clinical Trial Participants to Enable Assessment of Their Real-World Representativeness and Personalized Inference. Circulation Cardiovascular Quality And Outcomes 2025, 18: e011306. PMID: 40261065, PMCID: PMC12203226, DOI: 10.1161/circoutcomes.124.011306.
- Aminorroaya A, Dhingra L, Pedroso A, Shankar S, Coppi A, Khunte A, Foppa M, Brant L, Barreto S, Ribeiro A, Krumholz H, Oikonomou E, Khera R. Development and multinational validation of an ensemble deep learning algorithm for detecting and predicting structural heart disease using noisy single-lead electrocardiograms. European Heart Journal - Digital Health 2025, 6: 554-566. PMID: 40703117, PMCID: PMC12282373, DOI: 10.1093/ehjdh/ztaf034.
- Shankar S, Dhingra L, Aminorroaya A, Adejumo P, Nadkarni G, Xu H, Brandt C, Oikonomou E, Pedroso A, Khera R. Automated transformation of unstructured cardiovascular diagnostic reports into structured datasets using sequentially deployed large language models. European Heart Journal - Digital Health 2025, 6: 783-796. PMID: 40703108, PMCID: PMC12282380, DOI: 10.1093/ehjdh/ztaf030.
- Dhingra L, Aminorroaya A, Sangha V, Pedroso A, Shankar S, Coppi A, Foppa M, Brant L, Barreto S, Ribeiro A, Krumholz H, Oikonomou E, Khera R. Ensemble Deep Learning Algorithm for Structural Heart Disease Screening Using Electrocardiographic Images PRESENT SHD. Journal Of The American College Of Cardiology 2025, 85: 1302-1313. PMID: 40139886, PMCID: PMC12199746, DOI: 10.1016/j.jacc.2025.01.030.
- Aminorroaya A, Oikonomou E, Biswas D, Jastreboff A, Khera R. Effects of Tirzepatide in Type 2 Diabetes Individual Variation and Relationship to Cardiometabolic Outcomes. Journal Of The American College Of Cardiology 2025, 85: 1858-1872. PMID: 40368575, PMCID: PMC12186526, DOI: 10.1016/j.jacc.2025.03.516.
- Aminorroaya A, Dhingra L, Oikonomou E, Khera R. Evaluation of a Machine Learning-Guided Strategy for Elevated Lipoprotein(a) Screening in Health Systems. Circulation Genomic And Precision Medicine 2025, 18: e004632. PMID: 39846171, PMCID: PMC11835527, DOI: 10.1161/circgen.124.004632.
- Dhingra L, Aminorroaya A, Sangha V, Pedroso A, Asselbergs F, Brant L, Barreto S, Ribeiro A, Krumholz H, Oikonomou E, Khera R. Heart failure risk stratification using artificial intelligence applied to electrocardiogram images: a multinational study. European Heart Journal 2025, 46: 1044-1053. PMID: 39804243, PMCID: PMC12086686, DOI: 10.1093/eurheartj/ehae914.
- Dhingra L, Sangha V, Aminorroaya A, Bryde R, Gaballa A, Ali A, Mehra N, Krumholz H, Sen S, Kramer C, Martinez M, Desai M, Oikonomou E, Khera R. A Multicenter Evaluation of the Impact of Therapies on Deep Learning-Based Electrocardiographic Hypertrophic Cardiomyopathy Markers. The American Journal Of Cardiology 2024, 237: 35-40. PMID: 39581517, PMCID: PMC11761372, DOI: 10.1016/j.amjcard.2024.11.028.
- Oikonomou E, Khera R. Expanding artificial intelligence to understudied populations: congenital heart disease as the next frontier. European Heart Journal 2024, 46: 869-871. PMID: 39523016, PMCID: PMC11879170, DOI: 10.1093/eurheartj/ehae737.
- Dhingra LS, Aminorroaya A, Sangha V, Pedroso AF, Shankar SV, Coppi A, Foppa M, Brant LC, Barreto SM, Ribeiro ALP, Krumholz HM, Oikonomou EK, Khera R. An Ensemble Deep Learning Algorithm for Structural Heart Disease Screening Using Electrocardiographic Images: PRESENT SHD. MedRxiv 2024 PMID: 39417095, DOI: 10.1101/2024.10.06.24314939.
- Aminorroaya A, Dhingra LS, Pedroso Camargos A, Vasisht Shankar S, Coppi A, Khunte A, Foppa M, Brant LC, Barreto SM, Ribeiro ALP, Krumholz HM, Oikonomou EK, Khera R. Development and Multinational Validation of an Ensemble Deep Learning Algorithm for Detecting and Predicting Structural Heart Disease Using Noisy Single-lead Electrocardiograms. MedRxiv 2024 PMID: 39417103, DOI: 10.1101/2024.10.07.24314974.
- Shankar SV, Dhingra LS, Aminorroaya A, Adejumo P, Nadkarni GN, Xu H, Brandt C, Oikonomou EK, Pedroso AF, Khera R. Automated Transformation of Unstructured Cardiovascular Diagnostic Reports into Structured Datasets Using Sequentially Deployed Large Language Models. MedRxiv 2024 PMID: 39417094, DOI: 10.1101/2024.10.08.24315035.
- Thangaraj P, Benson S, Oikonomou E, Asselbergs F, Khera R. Cardiovascular care with digital twin technology in the era of generative artificial intelligence. European Heart Journal 2024, 45: 4808-4821. PMID: 39322420, PMCID: PMC11638093, DOI: 10.1093/eurheartj/ehae619.
- Thangaraj PM, Shankar SV, Huang S, Nadkarni GN, Mortazavi BJ, Oikonomou EK, Khera R. A Novel Digital Twin Strategy to Examine the Implications of Randomized Clinical Trials for Real-World Populations. MedRxiv 2024 PMID: 38585929, DOI: 10.1101/2024.03.25.24304868.
- Oikonomou EK, Sangha V, Shankar SV, Coppi A, Krumholz HM, Nasir K, Miller EJ, Gallegos-Kattan C, Al-Kindi S, Khera R. Tracking the pre-clinical progression of transthyretin amyloid cardiomyopathy using artificial intelligence-enabled electrocardiography and echocardiography. MedRxiv 2024 PMID: 39252891, DOI: 10.1101/2024.08.25.24312556.
- Oikonomou E, Khera R. Designing medical artificial intelligence systems for global use: focus on interoperability, scalability, and accessibility. Hellenic Journal Of Cardiology 2024, 81: 9-17. PMID: 39025234, DOI: 10.1016/j.hjc.2024.07.003.
- Holste G, Oikonomou E, Mortazavi B, Wang Z, Khera R. Efficient deep learning-based automated diagnosis from echocardiography with contrastive self-supervised learning. Communications Medicine 2024, 4: 133. PMID: 38971887, PMCID: PMC11227494, DOI: 10.1038/s43856-024-00538-3.
- Oikonomou EK, Vaid A, Holste G, Coppi A, McNamara RL, Baloescu C, Krumholz HM, Wang Z, Apakama DJ, Nadkarni GN, Khera R. Artificial intelligence-guided detection of under-recognized cardiomyopathies on point-of-care cardiac ultrasound: a multi-center study. MedRxiv 2024 PMID: 38559021, DOI: 10.1101/2024.03.10.24304044.
- Aminorroaya A, Dhingra LS, Camargos AP, Shankar SV, Khunte A, Sangha V, Sen S, McNamara RL, Haynes N, Oikonomou EK, Khera R. Study Protocol for the Artificial Intelligence-Driven Evaluation of Structural Heart Diseases Using Wearable Electrocardiogram (ID-SHD). MedRxiv 2024 PMID: 38562867, DOI: 10.1101/2024.03.18.24304477.
- L’Italien G, Oikonomou E, Khera R, Potashman M, Beiner M, Maclaine G, Schmahmann J, Perlman S, Coric V. Video-Based Kinematic Analysis of Movement Quality in a Phase 3 Clinical Trial of Troriluzole in Adults with Spinocerebellar Ataxia: A Post Hoc Analysis. Neurology And Therapy 2024, 13: 1287-1301. PMID: 38814532, PMCID: PMC11263303, DOI: 10.1007/s40120-024-00625-6.
- Chan K, Wahome E, Tsiachristas A, Antonopoulos A, Patel P, Lyasheva M, Kingham L, West H, Oikonomou E, Volpe L, Mavrogiannis M, Nicol E, Mittal T, Halborg T, Kotronias R, Adlam D, Modi B, Rodrigues J, Screaton N, Kardos A, Greenwood J, Sabharwal N, De Maria G, Munir S, McAlindon E, Sohan Y, Tomlins P, Siddique M, Kelion A, Shirodaria C, Pugliese F, Petersen S, Blankstein R, Desai M, Gersh B, Achenbach S, Libby P, Neubauer S, Channon K, Deanfield J, Antoniades C, Consortium O, Thomas S, Denton J, Farral R, Taylor C, Qin W, Kasongo M, Anthony S, Banning A, Xie C, Kharbanda R, Pritchard A, Halborg T, Syed N, Fry S, Mathers C, Rose A, Hudson G, Bajaj A, Das I, Deshpande A, Rao P, Lawday D, Mirsadraee S, Hudson B, Berry C, Marwan M, Maurovich-Horvat P, He G, Lin W, Fan L, Takahashi N, Kondo H, Dai N, Ge J, Koo B, Guglielmo M, Pontone G, Huck D, Benedek T, Rajani R, Vilic D, Aljazzaf H, Mun M, Benedetti G, Preston R, Raisi-Estabragh Z, Connolly D, Sharma V, Grenfell R, Bradlow W, Schmitt M, Serfaty F, Gottlieb I, Neves M, Newby D, Dweck M, Hatem S, Redheuil A, Benetos G, Beer M, Granillo G, Selvanayagam J, Lopez-Jimenez F, De Bosscher R, Tavildari A, Figtree G, Danad I, Shantouf R, Kietselaer B, Tousoulis D, Dangas G, Mehta N, Kontanidis C, Kunadian V, Fairbairn T. Inflammatory risk and cardiovascular events in patients without obstructive coronary artery disease: the ORFAN multicentre, longitudinal cohort study. The Lancet 2024, 403: 2606-2618. PMID: 38823406, PMCID: PMC11664027, DOI: 10.1016/s0140-6736(24)00596-8.
- Dhingra LS, Aminorroaya A, Camargos AP, Khunte A, Sangha V, McIntyre D, Chow CK, Asselbergs FW, Brant LC, Barreto SM, Ribeiro ALP, Krumholz HM, Oikonomou EK, Khera R. Using Artificial Intelligence to Predict Heart Failure Risk from Single-lead Electrocardiographic Signals: A Multinational Assessment. MedRxiv 2024 PMID: 38854022, DOI: 10.1101/2024.05.27.24307952.
- Thangaraj PM, Oikonomou EK, Dhingra LS, Aminorroaya A, Jayaram R, Suchard MA, Khera R. Computational Phenomapping of Randomized Clinical Trials to Enable Assessment of their Real-world Representativeness and Personalized Inference. MedRxiv 2024 PMID: 38798457, DOI: 10.1101/2024.05.15.24306285.
- Aminorroaya A, Dhingra L, Oikonomou E, Saadatagah S, Thangaraj P, Vasisht Shankar S, Spatz E, Khera R. Development and multinational validation of an algorithmic strategy for high Lp(a) screening. Nature Cardiovascular Research 2024, 3: 558-566. PMID: 39195936, PMCID: PMC12190734, DOI: 10.1038/s44161-024-00469-1.
- Oikonomou E, Aminorroaya A, Dhingra L, Partridge C, Velazquez E, Desai N, Krumholz H, Miller E, Khera R. Real-world evaluation of an algorithmic machine-learning-guided testing approach in stable chest pain: a multinational, multicohort study. European Heart Journal - Digital Health 2024, 5: 303-313. PMID: 38774380, PMCID: PMC11104476, DOI: 10.1093/ehjdh/ztae023.
- Dhingra LS, Aminorroaya A, Sangha V, Camargos AP, Asselbergs FW, Brant LC, Barreto SM, Ribeiro ALP, Krumholz HM, Oikonomou EK, Khera R. Scalable Risk Stratification for Heart Failure Using Artificial Intelligence applied to 12-lead Electrocardiographic Images: A Multinational Study. MedRxiv 2024 PMID: 38633808, DOI: 10.1101/2024.04.02.24305232.
- Oikonomou E, Khera R. Leveraging the Full Potential of Wearable Devices in Cardiomyopathies. Journal Of Cardiac Failure 2024, 30: 964-966. PMID: 38452997, DOI: 10.1016/j.cardfail.2024.02.011.
- Khunte A, Sangha V, Oikonomou EK, Dhingra LS, Aminorroaya A, Coppi A, Shankar SV, Mortazavi BJ, Bhatt DL, Krumholz HM, Nadkarni GN, Vaid A, Khera R. Automated Diagnostic Reports from Images of Electrocardiograms at the Point-of-Care. MedRxiv 2024 PMID: 38405776, DOI: 10.1101/2024.02.17.24302976.
- Sangha V, Khunte A, Holste G, Mortazavi B, Wang Z, Oikonomou E, Khera R. Biometric contrastive learning for data-efficient deep learning from electrocardiographic images. Journal Of The American Medical Informatics Association 2024, 31: 855-865. PMID: 38269618, PMCID: PMC10990541, DOI: 10.1093/jamia/ocae002.
- Thangaraj PM, Shankar SV, Oikonomou EK, Khera R. RCT-Twin-GAN Generates Digital Twins of Randomized Control Trials Adapted to Real-world Patients to Enhance their Inference and Application. MedRxiv 2023 PMID: 38106089, DOI: 10.1101/2023.12.06.23299464.
- Shankar SV, Oikonomou EK, Khera R. CarDS-Plus ECG Platform: Development and Feasibility Evaluation of a Multiplatform Artificial Intelligence Toolkit for Portable and Wearable Device Electrocardiograms. MedRxiv 2023 PMID: 37873174, DOI: 10.1101/2023.10.02.23296404.
- Oikonomou E, Khera R. Machine learning in precision diabetes care and cardiovascular risk prediction. Cardiovascular Diabetology 2023, 22: 259. PMID: 37749579, PMCID: PMC10521578, DOI: 10.1186/s12933-023-01985-3.
- Aminorroaya A, Dhingra L, Nargesi A, Oikonomou E, Krumholz H, Khera R. Use of Smart Devices to Track Cardiovascular Health Goals in the United States. JACC Advances 2023, 2: 100544. PMID: 38094515, PMCID: PMC10718569, DOI: 10.1016/j.jacadv.2023.100544.
- Khunte A, Sangha V, Oikonomou E, Dhingra L, Aminorroaya A, Mortazavi B, Coppi A, Brandt C, Krumholz H, Khera R. Detection of left ventricular systolic dysfunction from single-lead electrocardiography adapted for portable and wearable devices. Npj Digital Medicine 2023, 6: 124. PMID: 37433874, PMCID: PMC10336107, DOI: 10.1038/s41746-023-00869-w.
- Dhingra L, Aminorroaya A, Oikonomou E, Nargesi A, Wilson F, Krumholz H, Khera R. Use of Wearable Devices in Individuals With or at Risk for Cardiovascular Disease in the US, 2019 to 2020. JAMA Network Open 2023, 6: e2316634. PMID: 37285157, PMCID: PMC10248745, DOI: 10.1001/jamanetworkopen.2023.16634.
- Nargesi A, Clark C, Aminorroaya A, Chen L, Liu M, Reddy A, Amodeo S, Oikonomou E, Suchard M, McGuire D, Lin Z, Inzucchi S, Khera R. Persistence on Novel Cardioprotective Antihyperglycemic Therapies in the United States. The American Journal Of Cardiology 2023, 196: 89-98. PMID: 37012183, PMCID: PMC11007258, DOI: 10.1016/j.amjcard.2023.03.002.
- Kotanidis CP, Xie C, Alexander D, Rodrigues JCL, Burnham K, Mentzer A, O’Connor D, Knight J, Siddique M, Lockstone H, Thomas S, Kotronias R, Oikonomou EK, Badi I, Lyasheva M, Shirodaria C, Lumley SF, Constantinides B, Sanderson N, Rodger G, Chau KK, Lodge A, Tsakok M, Gleeson F, Adlam D, Rao P, Indrajeet D, Deshpande A, Bajaj A, Hudson BJ, Srivastava V, Farid S, Krasopoulos G, Sayeed R, Ho LP, Neubauer S, Newby DE, Channon KM, Deanfield J, Antoniades C, Consortium C, Ahern D, Ai Z, Ainsworth M, Allan C, Allcock A, Angus B, Ansari M, Arancibia-Cárcamo C, Aschenbrenner D, Attar M, Baillie J, Barnes E, Bashford-Rogers R, Bashyal A, Beer S, Berridge G, Beveridge A, Bibi S, Bicanic T, Blackwell L, Bowness P, Brent A, Brown A, Broxholme J, Buck D, Burnham K, Byrne H, Camara S, Ferreira I, Charles P, Chen W, Chen Y, Chong A, Clutterbuck E, Coles M, Conlon C, Cornall R, Cribbs A, Curion F, Davenport E, Davidson N, Davis S, Dendrou C, Dequaire J, Dib L, Docker J, Dold C, Dong T, Downes D, Drakesmith H, Dunachie S, Duncan D, Eijsbouts C, Esnouf R, Espinosa A, Etherington R, Fairfax B, Fairhead R, Fang H, Fassih S, Felle S, Mendoza M, Ferreira R, Fischer R, Foord T, Forrow A, Frater J, Fries A, Sanchez V, Garner L, Geeves C, Georgiou D, Godfrey L, Golubchik T, Vazquez M, Green A, Harper H, Harrington H, Heilig R, Hester S, Hill J, Hinds C, Hird C, Ho L, Hoekzema R, Hollis B, Hughes J, Hutton P, Jackson-Wood M, Jainarayanan A, James-Bott A, Jansen K, Jeffery K, Jones E, Jostins L, Kerr G, Kim D, Klenerman P, Knight J, Kumar V, Sharma P, Kurupati P, Kwok A, Lee A, Linder A, Lockett T, Lonie L, Lopopolo M, Lukoseviciute M, Luo J, Marinou S, Marsden B, Martinez J, Matthews P, Mazurczyk M, McGowan S, McKechnie S, Mead A, Mentzer A, Mi Y, Monaco C, Montadon R, Napolitani G, Nassiri I, Novak A, O'Brien D, O'Connor D, O'Donnell D, Ogg G, Overend L, Park I, Pavord I, Peng Y, Penkava F, Pinho M, Perez E, Pollard A, Powrie F, Psaila B, Quan T, Repapi E, Revale S, Silva-Reyes L, Richard J, Rich-Griffin C, Ritter T, Rollier C, Rowland M, Ruehle F, Salio M, Sansom S, Peres R, Delgado A, Sauka-Spengler T, Schwessinger R, Scozzafava G, Screaton G, Seigal A, Semple M, Sergeant M, Karali C, Sims D, Skelly D, Slawinski H, Sobrinodiaz A, Sousos N, Stafford L, Stockdale L, Strickland M, Sumray O, Sun B, Taylor C, Taylor S, Taylor A, Thongjuea S, Thraves H, Todd J, Tomic A, Tong O, Trebes A, Trzupek D, Tucci F, Turtle L, Udalova I, Uhlig H, van Grinsven E, Vendrell I, Verheul M, Voda A, Wang G, Wang L, Wang D, Watkinson P, Watson R, Weinberger M, Whalley J, Witty L, Wray K, Xue L, Yeung H, Yin Z, Young R, Youngs J, Zhang P, Zurke Y, investigators O, Banning A, Antonopoulos A, Bajaj A, Kelion A, Deshpande A, Kardos A, Hudson B, Koo B, Shirodaria C, Xie C, Kotanidis C, Mahon C, Berry C, Adlam D, Newby D, Connolly D, Scaletta D, Alexander D, Nicol E, McAlindon E, Oikonomou E, Pugliese F, Pontone G, Benedetti G, He G, West H, Kondo H, Benedek I, Das I, Deanfield J, Graby J, Greenwood J, Rodrigues J, Ge J, Channon K, Fabritz L, Fan L, Kingham L, Guglielmo M, Lyasheva M, Schmitt M, Beer M, Anderson M, Desai M, Marwan M, Takahashi N, Mehta N, Dai N, Screaton N, Sabharwal N, Maurovich-Horvat P, Rao P, Kotronias R, Kharbanda R, Preston R, Wood R, Blankstein R, Rajani R, Mirsadraee S, Munir S, Thomas S, Neubauer S, Klömpken S, Petersen S, Achenbach S, Anthony S, Mak S, Mittal T, Benedek T, Sharma V, Lin W. Constructing custom-made radiotranscriptomic signatures of vascular inflammation from routine CT angiograms: a prospective outcomes validation study in COVID-19. The Lancet Digital Health 2022, 4: e705-e716. PMID: 36038496, PMCID: PMC9417284, DOI: 10.1016/s2589-7500(22)00132-7.
- Kwan JM, Oikonomou EK, Henry ML, Sinusas AJ. Multimodality Advanced Cardiovascular and Molecular Imaging for Early Detection and Monitoring of Cancer Therapy-Associated Cardiotoxicity and the Role of Artificial Intelligence and Big Data. Frontiers In Cardiovascular Medicine 2022, 9: 829553. PMID: 35369354, PMCID: PMC8964995, DOI: 10.3389/fcvm.2022.829553.
- Oikonomou EK, Suchard MA, McGuire DK, Khera R. Phenomapping-Derived Tool to Individualize the Effect of Canagliflozin on Cardiovascular Risk in Type 2 Diabetes. Diabetes Care 2022, 45: 965-974. PMID: 35120199, PMCID: PMC9016734, DOI: 10.2337/dc21-1765.
- Bellumkonda L, Oikonomou EK, Hsueh C, Maulion C, Testani J, Patel J. The impact of induction therapy on mortality and treated rejection in cardiac transplantation: A retrospective study. The Journal Of Heart And Lung Transplantation 2022, 41: 482-491. PMID: 35094919, DOI: 10.1016/j.healun.2022.01.008.
- Antonopoulos A, Angelopoulos A, Papanikolaou P, Simantiris S, Oikonomou E, Vamvakaris K, Koumpoura A, Farmaki M, Trivella M, Vlachopoulos C, Tsioufis K, Antoniades C, Tousoulis D. Biomarkers of Vascular Inflammation for Cardiovascular Risk Prognostication A Meta-Analysis. JACC Cardiovascular Imaging 2021, 15: 460-471. PMID: 34801448, DOI: 10.1016/j.jcmg.2021.09.014.
- Antoniades C, Oikonomou E. Artificial intelligence in cardiovascular imaging—principles, expectations, and limitations. European Heart Journal 2021, 45: 1322-1326. PMID: 34557898, PMCID: PMC11015951, DOI: 10.1093/eurheartj/ehab678.
- Feher A, Boutagy NE, Oikonomou EK, Liu YH, Miller EJ, Sinusas AJ, Hinchcliff M. Association Between Impaired Myocardial Flow Reserve on 82Rubidium Positron Emission Tomography Imaging and Adverse Events in Patients With Autoimmune Rheumatic Disease. Circulation Cardiovascular Imaging 2021, 14: e012208. PMID: 34503339, PMCID: PMC8475774, DOI: 10.1161/circimaging.120.012208.
- Oikonomou EK, Antonopoulos AS, Schottlander D, Marwan M, Mathers C, Tomlins P, Siddique M, Klüner LV, Shirodaria C, Mavrogiannis MC, Thomas S, Fava A, Deanfield J, Channon KM, Neubauer S, Desai MY, Achenbach S, Antoniades C. Standardized measurement of coronary inflammation using cardiovascular computed tomography: integration in clinical care as a prognostic medical device. Cardiovascular Research 2021, 117: 2677-2690. PMID: 34450625, DOI: 10.1093/cvr/cvab286.
- Kondo H, Akoumianakis I, Badi I, Akawi N, Kotanidis CP, Polkinghorne M, Stadiotti I, Sommariva E, Antonopoulos AS, Carena MC, Oikonomou EK, Reus EM, Sayeed R, Krasopoulos G, Srivastava V, Farid S, Chuaiphichai S, Shirodaria C, Channon KM, Casadei B, Antoniades C. Effects of canagliflozin on human myocardial redox signalling: clinical implications. European Heart Journal 2021, 42: 4947-4960. PMID: 34293101, PMCID: PMC8691807, DOI: 10.1093/eurheartj/ehab420.
- Feher A, Boutagy NE, Oikonomou EK, Thorn S, Liu YH, Miller EJ, Sinusas AJ, Hinchcliff M. Impaired Myocardial Flow Reserve on 82Rubidium Positron Emission Tomography/Computed Tomography in Patients With Systemic Sclerosis. The Journal Of Rheumatology 2021, 48: 1574-1582. PMID: 34266986, PMCID: PMC10275580, DOI: 10.3899/jrheum.210040.
- Gallegos C, Oikonomou EK, Grimshaw A, Gulati M, Young BD, Miller EJ. Non-steroidal treatment of cardiac sarcoidosis: A systematic review. IJC Heart & Vasculature 2021, 34: 100782. PMID: 33997256, PMCID: PMC8105294, DOI: 10.1016/j.ijcha.2021.100782.
- Klüner LV, Oikonomou EK, Antoniades C. Assessing Cardiovascular Risk by Using the Fat Attenuation Index in Coronary CT Angiography. Radiology Cardiothoracic Imaging 2021, 3: e200563. PMID: 33778665, PMCID: PMC7977699, DOI: 10.1148/ryct.2021200563.
- Nolan M, Oikonomou E, Silversides C, Hines M, Thompson K, Campbell B, Amir E, Maxwell C, Thavendiranathan P. Impact of Cancer Therapy-Related Cardiac Dysfunction on Risk of Heart Failure in Pregnancy. JACC CardioOncology 2020, 2: 153-162. PMID: 34396225, PMCID: PMC8352036, DOI: 10.1016/j.jaccao.2020.04.007.
- Akoumianakis I, Badi I, Douglas G, Chuaiphichai S, Herdman L, Akawi N, Margaritis M, Antonopoulos AS, Oikonomou EK, Psarros C, Galiatsatos N, Tousoulis D, Kardos A, Sayeed R, Krasopoulos G, Petrou M, Schwahn U, Wohlfart P, Tennagels N, Channon KM, Antoniades C. Insulin-induced vascular redox dysregulation in human atherosclerosis is ameliorated by dipeptidyl peptidase 4 inhibition. Science Translational Medicine 2020, 12 PMID: 32350133, PMCID: PMC7212010, DOI: 10.1126/scitranslmed.aav8824.
- Oikonomou EK, Siddique M, Antoniades C. Artificial intelligence in medical imaging: A radiomic guide to precision phenotyping of cardiovascular disease. Cardiovascular Research 2020, 116: 2040-2054. PMID: 32090243, PMCID: PMC7585409, DOI: 10.1093/cvr/cvaa021.
- Oikonomou EK. Molecular imaging to guide precision diagnosis and prevention of cancer therapeutics-related cardiac dysfunction. Expert Review Of Molecular Diagnostics 2020, 20: 355-358. PMID: 31944137, DOI: 10.1080/14737159.2020.1717336.
- Nolan M, Oikonomou EK, Silversides CK, Hines MR, Thompson KA, Campbell BA, Amir E, Maxwell C, Thavendiranathan P. J Am Coll Cardiol CardioOnc. 2020 Jun, 2 (2) 153-162.
- Oikonomou EK, Kokkinidis DG, Kampaktsis PN, Amir EA, Marwick TH, Gupta D, Thavendiranathan P. Assessment of Prognostic Value of Left Ventricular Global Longitudinal Strain for Early Prediction of Chemotherapy-Induced Cardiotoxicity. JAMA Cardiology 2019, 4: 1007-1018. PMID: 31433450, PMCID: PMC6705141, DOI: 10.1001/jamacardio.2019.2952.
- Oikonomou EK, West HW, Antoniades C. Cardiac Computed Tomography. Arteriosclerosis Thrombosis And Vascular Biology 2019, 39: 2207-2219. PMID: 31510795, DOI: 10.1161/atvbaha.119.312899.
- Elnabawi YA, Oikonomou EK, Dey AK, Mancio J, Rodante JA, Aksentijevich M, Choi H, Keel A, Erb-Alvarez J, Teague HL, Joshi AA, Playford MP, Lockshin B, Choi AD, Gelfand JM, Chen MY, Bluemke DA, Shirodaria C, Antoniades C, Mehta NN. Association of Biologic Therapy With Coronary Inflammation in Patients With Psoriasis as Assessed by Perivascular Fat Attenuation Index. JAMA Cardiology 2019, 4: 885-891. PMID: 31365032, PMCID: PMC6669789, DOI: 10.1001/jamacardio.2019.2589.
- Antonopoulos AS, Odutayo A, Oikonomou EK, Trivella M, Petrou M, Collins GS, Antoniades C, group S, Akoumianakis I, Channon K, Herdman L, Margaritis M, Neubauer S, Thomas S, Fremes S, Karkhanis R, Rade J, Fukui T, Nishida H, Takanashi S, Hwang H, Kim K, Mannacio L, Mannacio V, Nakano J, Perrault L, Kardos A, Okabayashi H, Tousoulis D, Kelion A, Sabharwal N, Krasopoulos G, Sayeed R, Taggart D. Development of a risk score for early saphenous vein graft failure: An individual patient data meta-analysis. Journal Of Thoracic And Cardiovascular Surgery 2019, 160: 116-127.e4. PMID: 31606176, PMCID: PMC7322547, DOI: 10.1016/j.jtcvs.2019.07.086.
- Papanastasiou CA, Kokkinidis DG, Jonnalagadda AK, Oikonomou EK, Kampaktsis PN, Garcia MJ, Myerson SG, Karamitsos TD. Meta-Analysis of Transthoracic Echocardiography Versus Cardiac Magnetic Resonance for the Assessment of Aortic Regurgitation After Transcatheter Aortic Valve Implantation. The American Journal Of Cardiology 2019, 124: 1246-1251. PMID: 31466694, DOI: 10.1016/j.amjcard.2019.07.036.
- Papanastasiou CA, Kokkinidis DG, Kampaktsis PN, Bikakis I, Cunha DK, Oikonomou EK, Greenwood JP, Garcia MJ, Karamitsos TD. The Prognostic Role of Late Gadolinium Enhancement in Aortic Stenosis A Systematic Review and Meta-Analysis. JACC Cardiovascular Imaging 2019, 13: 385-392. PMID: 31326491, DOI: 10.1016/j.jcmg.2019.03.029.
- Chuy K, Oikonomou EK, Postow MA, Callahan MK, Chapman PB, Shoushtari AN, Neilan TG, Fradley MG, Ramanathan LV, Wolchok JD, Steingart RM, Gupta D. Myocarditis Surveillance in Patients with Advanced Melanoma on Combination Immune Checkpoint Inhibitor Therapy: The Memorial Sloan Kettering Cancer Center Experience. The Oncologist 2019, 24: e196-e197. PMID: 30910868, PMCID: PMC6516118, DOI: 10.1634/theoncologist.2019-0040.
- Mancio J, Oikonomou EK, Antoniades C. Perivascular adipose tissue and coronary atherosclerosis. Heart 2018, 104: 1654. PMID: 29853488, DOI: 10.1136/heartjnl-2017-312324.
- Kokkinidis DG, Papanastasiou CA, Jonnalagadda AK, Oikonomou EK, Theochari CA, Palaiodimos L, Karvounis HI, Armstrong EJ, Faillace RT, Giannakoulas G. The predictive value of baseline pulmonary hypertension in early and long term cardiac and all-cause mortality after transcatheter aortic valve implantation for patients with severe aortic valve stenosis: A systematic review and meta-analysis. Cardiovascular Revascularization Medicine 2018, 19: 859-867. PMID: 29724516, DOI: 10.1016/j.carrev.2018.03.015.
- Theochari CA, Michalopoulos G, Oikonomou EK, Giannopoulos S, Doulamis IP, Villela MA, Kokkinidis DG. Heart transplantation versus left ventricular assist devices as destination therapy or bridge to transplantation for 1-year mortality: a systematic review and meta-analysis. Annals Of Cardiothoracic Surgery 2018, 7: 3-11. PMID: 29492379, PMCID: PMC5827119, DOI: 10.21037/acs.2017.09.18.
- Tsilimigras DI, Oikonomou EK, Moris D, Schizas D, Economopoulos KP, Mylonas KS. Stem Cell Therapy for Congenital Heart Disease. Circulation 2017, 136: 2373-2385. PMID: 29229621, DOI: 10.1161/circulationaha.117.029607.
- Oikonomou EK. Clinical and translational science in cardiovascular research: highlights from the American Heart Association Scientific Sessions 2017. Cardiovascular Research 2017, 114: e6-e8. PMID: 29202178, DOI: 10.1093/cvr/cvx233.
- Papanastasiou CA, Kokkinidis DG, Oikonomou EK, Mantziaris VG, Foley TR, Karamitsos TD, Waldo SW, Armstrong EJ. Pregnancy associated plasma protein-A as a prognostic biomarker of all-cause mortality and cardiovascular events in patients presenting with chest pain: a systematic review. Biomarkers 2017, 23: 1-9. PMID: 29144175, DOI: 10.1080/1354750x.2017.1397194.
- Toutouzas K, Skoumas J, Koutagiar I, Benetos G, Pianou N, Georgakopoulos A, Galanakos S, Antonopoulos A, Drakopoulou M, Oikonomou EK, Kafouris P, Athanasiadis E, Metaxas M, Spyrou G, Pallantza Z, Galiatsatos N, Aggeli C, Antoniades C, Keramida G, Peters AM, Anagnostopoulos CD, Tousoulis D. Vascular inflammation and metabolic activity in hematopoietic organs and liver in familial combined hyperlipidemia and heterozygous familial hypercholesterolemia. Journal Of Clinical Lipidology 2017, 12: 33-43. PMID: 29174439, DOI: 10.1016/j.jacl.2017.10.019.
- Kampaktsis PN, Oikonomou EK, Y. Choi D, Cheung JW. Efficacy of ganglionated plexi ablation in addition to pulmonary vein isolation for paroxysmal versus persistent atrial fibrillation: a meta-analysis of randomized controlled clinical trials. Journal Of Interventional Cardiac Electrophysiology 2017, 50: 253-260. PMID: 28887742, DOI: 10.1007/s10840-017-0285-z.
- Oikonomou EK, Antoniades C. Immunometabolic Regulation of Vascular Redox State: The Role of Adipose Tissue. Antioxidants & Redox Signaling 2017, 29: 313-336. PMID: 28657335, DOI: 10.1089/ars.2017.7017.
- Antonopoulos AS, Sanna F, Sabharwal N, Thomas S, Oikonomou EK, Herdman L, Margaritis M, Shirodaria C, Kampoli AM, Akoumianakis I, Petrou M, Sayeed R, Krasopoulos G, Psarros C, Ciccone P, Brophy CM, Digby J, Kelion A, Uberoi R, Anthony S, Alexopoulos N, Tousoulis D, Achenbach S, Neubauer S, Channon KM, Antoniades C. Detecting human coronary inflammation by imaging perivascular fat. Science Translational Medicine 2017, 9 PMID: 28701474, DOI: 10.1126/scitranslmed.aal2658.
- Kokkinidis DG, Oikonomou EK, Papanastasiou CA, Theochari CA, Giannakoulas G. Methodological Remarks in the Meta-Analysis on the Impact of Baseline Pulmonary Hypertension on Post-Transcatheter Aortic Valve Implantation Outcomes. The American Journal Of Cardiology 2017, 120: 513-514. PMID: 28554487, DOI: 10.1016/j.amjcard.2017.04.032.
- Margaritis M, Sanna F, Lazaros G, Akoumianakis I, Patel S, Antonopoulos AS, Duke C, Herdman L, Psarros C, Oikonomou EK, Shirodaria C, Petrou M, Sayeed R, Krasopoulos G, Lee R, Tousoulis D, Channon KM, Antoniades C. Predictive value of telomere length on outcome following acute myocardial infarction: evidence for contrasting effects of vascular vs. blood oxidative stress. European Heart Journal 2017, 38: 3094-3104. PMID: 28444175, PMCID: PMC5837455, DOI: 10.1093/eurheartj/ehx177.
- Taggart DP, Amin S, Djordjevic J, Oikonomou EK, Thomas S, Kampoli AM, Sabharwal N, Antoniades C, Krasopoulos G. A prospective study of external stenting of saphenous vein grafts to the right coronary artery: the VEST II study. European Journal Of Cardio-Thoracic Surgery 2017, 51: 952-958. PMID: 28379404, DOI: 10.1093/ejcts/ezw438.
- De Maria GL, Alkhalil M, Oikonomou EK, Wolfrum M, Choudhury RP, Banning AP. Role of deferred stenting in patients with ST elevation myocardial infarction treated with primary percutaneous coronary intervention: A systematic review and meta‐analysis. Journal Of Interventional Cardiology 2017, 30: 264-273. PMID: 28370496, DOI: 10.1111/joic.12380.
- Lazaros G, Antonopoulos AS, Oikonomou EK, Vasileiou P, Oikonomou E, Stroumpouli E, Karavidas A, Antoniades C, Tousoulis D. Prognostic implications of epicardial fat volume quantification in acute pericarditis. European Journal Of Clinical Investigation 2016, 47: 129-136. PMID: 27931089, DOI: 10.1111/eci.12711.
- Oikonomou EK, Repanas TI, Papanastasiou C, Kokkinidis DG, Miligkos M, Feher A, Gupta D, Kampaktsis PN. The effect of in-hospital acquired thrombocytopenia on the outcome of patients with acute coronary syndromes: A systematic review and meta-analysis. Thrombosis Research 2016, 147: 64-71. PMID: 27689317, PMCID: PMC5515466, DOI: 10.1016/j.thromres.2016.09.026.
Biography
Evangelos K. Oikonomou, MD, DPhil, is a cardiovascular medicine specialist who focuses on the diagnosis and management of heart and blood vessel diseases. He provides advanced care for a wide range of cardiovascular conditions, using both state-of-the-art imaging techniques and data-driven approaches to personalize patient assessment and treatment.
“I strive to build long-term relationships with my patients and emphasize the prevention of cardiovascular disease,” Dr. Oikonomou says. “I believe every patient is unique. In my practice, I listen carefully and work collaboratively to develop personalized treatment plans grounded in the best available evidence. Helping individuals take proactive steps to preserve their heart health is one of the most rewarding aspects of my work.”
As a clinical fellow in cardiovascular medicine at Yale School of Medicine, Dr. Oikonomou’s research bridges medicine and data science with the goal of enhancing how heart disease is detected and managed. He develops artificial intelligence tools that help identify heart disease patterns from imaging tests such as echocardiograms and cardiac CT scans. These methods improve the detection of both common and rare cardiac conditions and support more accurate risk assessment. Dr. Oikonomou also investigates how inflammation in the tissues surrounding blood vessels affects heart health and works to create tools that guide more tailored treatments for patients. His research includes the use of computer vision and machine learning methods to find personalized responses to therapies, which can make clinical trials more efficient and patient care more precise.
Dr. Oikonomou is widely published in top journals and has received notable awards from the American Heart Association, American College of Cardiology, European Society of Cardiology and American Society for Clinical Investigation, as well as the Radcliffe Department of Medicine Graduate Prize from the University of Oxford. “Cardiology brings together a unique blend of acute and chronic care, across all ages and disease spectrums,” Dr. Oikonomou says. “I was drawn to the intellectual rigor of integrating history, physical examination, and imaging diagnostics to make precise diagnoses, and to a field that continuously evolves through impactful clinical trials and innovation.”
He received his medical degree from the University of Athens Medical School in Greece, completed doctoral studies in medical sciences at the University of Oxford in the United Kingdom, and his residency, as well as clinical and post-doctoral research fellowship in cardiovascular medicine at Yale School of Medicine.
Titles
- Assistant Professor
Education & Training
- Post-doctoral fellowYale School of Medicine (2025)
- Clinical fellowYale School of Medicine (2025)
- ResidentYale School of Medicine (2021)
- InternYale School of Medicine (2020)
- DPhilUniversity of Oxford (2020)
- MDUniversity of Athens School of Health Sciences (2015)
Languages Spoken
- English
- Ελληνικά (Greek)
Additional Information
Honors & Recognitions
- Wiesman Award for Excellence in Early Career ATTR Research: ATTR Early- Career Research Forum (2025)
- Robert A. Winn Excellence in Clinical Trials Career Development Award: VCU Massey Comprehensive Cancer Center (2025)
- Heart Tank For the Cardiovascular Investigator - Imaging (Winner): American College of Cardiology (ACC) (2024)
- Trainee Poster Award Winner: CERSI Summit 2024 (2024)
- ASCI emerging generation (e-Gen) award: American Society of Clinical Investigation (ASCI) (2024)
- Elizabeth Barrett-Connor Research Award in Epidemiology and Prevention (Winner): American Heart Association (2023)
- Ruth L. Kirschstein Postdoctoral Individual National Research Service Award (F32): National Heart, Lung, and Blood Institute (NIH) (2023)
- Yale/Mayo CERSI scholar 2022-2023: Yale University & Mayo Clinic Center for Excellence in Regulatory Science and Innovation (CERSI) (2022)
- Council on Lifestyle and Cardiometabolic Health Early Career Investigator Award: American Heart Association (2021)
- First Place Award (Clinical Fellows): Northwestern Cardiovascular Young Investigators' Forum (2021)
Board Certifications
- AB of Internal Medicine, Internal Medicine (2022)
Professional Service
- European Heart Journal (2024 - Present): Associate Editor
Publications
- Holste G, Oikonomou E, Tokodi M, Kovács A, Wang Z, Khera R. Complete AI-Enabled Echocardiography Interpretation With Multitask Deep Learning. JAMA: The Journal Of The American Medical Association 2025, 334: 306-318. PMID: 40549400, PMCID: PMC12186137, DOI: 10.1001/jama.2025.8731.
- Oikonomou E, Sangha V, Shankar S, Coppi A, Krumholz H, Nasir K, Miller E, Gallegos Kattan C, Al-Mallah M, Al-Kindi S, Khera R. Artificial intelligence-enabled electrocardiography and echocardiography to track preclinical progression of transthyretin amyloid cardiomyopathy. European Heart Journal 2025, 46: 3651-3662. PMID: 40679604, PMCID: PMC12488324, DOI: 10.1093/eurheartj/ehaf450.
- Oikonomou E, Sangha V, Dhingra L, Aminorroaya A, Coppi A, Krumholz H, Baldassarre L, Khera R. Artificial Intelligence–Enhanced Risk Stratification of Cancer Therapeutics–Related Cardiac Dysfunction Using Electrocardiographic Images. Circulation Cardiovascular Quality And Outcomes 2024, 18: e011504. PMID: 39221857, PMCID: PMC11745701, DOI: 10.1161/circoutcomes.124.011504.
- Oikonomou E, Vaid A, Holste G, Coppi A, McNamara R, Baloescu C, Krumholz H, Wang Z, Apakama D, Nadkarni G, Khera R. Artificial intelligence-guided detection of under-recognised cardiomyopathies on point-of-care cardiac ultrasonography: a multicentre study. The Lancet Digital Health 2025, 7: e113-e123. PMID: 39890242, PMCID: PMC12084816, DOI: 10.1016/s2589-7500(24)00249-8.
- Oikonomou E, Khera R. Artificial intelligence-enhanced patient evaluation: bridging art and science. European Heart Journal 2024, 45: 3204-3218. PMID: 38976371, PMCID: PMC11400875, DOI: 10.1093/eurheartj/ehae415.
- Khera R, Oikonomou E, Nadkarni G, Morley J, Wiens J, Butte A, Topol E. Transforming Cardiovascular Care With Artificial Intelligence: From Discovery to Practice JACC State-of-the-Art Review. Journal Of The American College Of Cardiology 2024, 84: 97-114. PMID: 38925729, PMCID: PMC12204085, DOI: 10.1016/j.jacc.2024.05.003.
- Oikonomou E, Holste G, Yuan N, Coppi A, McNamara R, Haynes N, Vora A, Velazquez E, Li F, Menon V, Kapadia S, Gill T, Nadkarni G, Krumholz H, Wang Z, Ouyang D, Khera R. A Multimodal Video-Based AI Biomarker for Aortic Stenosis Development and Progression. JAMA Cardiology 2024, 9: 534-544. PMID: 38581644, PMCID: PMC10999005, DOI: 10.1001/jamacardio.2024.0595.
- Oikonomou E, Thangaraj P, Bhatt D, Ross J, Young L, Krumholz H, Suchard M, Khera R. An explainable machine learning-based phenomapping strategy for adaptive predictive enrichment in randomized clinical trials. Npj Digital Medicine 2023, 6: 217. PMID: 38001154, PMCID: PMC10673945, DOI: 10.1038/s41746-023-00963-z.
- Holste G, Oikonomou E, Mortazavi B, Coppi A, Faridi K, Miller E, Forrest J, McNamara R, Ohno-Machado L, Yuan N, Gupta A, Ouyang D, Krumholz H, Wang Z, Khera R. Severe aortic stenosis detection by deep learning applied to echocardiography. European Heart Journal 2023, 44: 4592-4604. PMID: 37611002, PMCID: PMC11004929, DOI: 10.1093/eurheartj/ehad456.
- Oikonomou EK, Spatz ES, Suchard MA, Khera R. Individualising intensive systolic blood pressure reduction in hypertension using computational trial phenomaps and machine learning: a post-hoc analysis of randomised clinical trials. The Lancet Digital Health 2022, 4: e796-e805. PMID: 36307193, PMCID: PMC9768739, DOI: 10.1016/s2589-7500(22)00170-4.
- Oikonomou EK, Van Dijk D, Parise H, Suchard MA, de Lemos J, Antoniades C, Velazquez EJ, Miller EJ, Khera R. A phenomapping-derived tool to personalize the selection of anatomical vs. functional testing in evaluating chest pain (ASSIST). European Heart Journal 2021, 42: 2536-2548. PMID: 33881513, PMCID: PMC8488385, DOI: 10.1093/eurheartj/ehab223.
- Oikonomou EK, Desai MY, Marwan M, Kotanidis CP, Antonopoulos AS, Schottlander D, Channon KM, Neubauer S, Achenbach S, Antoniades C. Perivascular Fat Attenuation Index Stratifies Cardiac Risk Associated With High-Risk Plaques in the CRISP-CT Study. Journal Of The American College Of Cardiology 2020, 76: 755-757. PMID: 32762910, DOI: 10.1016/j.jacc.2020.05.078.
- Oikonomou EK, Williams MC, Kotanidis CP, Desai MY, Marwan M, Antonopoulos AS, Thomas KE, Thomas S, Akoumianakis I, Fan LM, Kesavan S, Herdman L, Alashi A, Centeno EH, Lyasheva M, Griffin BP, Flamm SD, Shirodaria C, Sabharwal N, Kelion A, Dweck MR, Van Beek EJR, Deanfield J, Hopewell JC, Neubauer S, Channon KM, Achenbach S, Newby DE, Antoniades C. A novel machine learning-derived radiotranscriptomic signature of perivascular fat improves cardiac risk prediction using coronary CT angiography. European Heart Journal 2019, 40: 3529-3543. PMID: 31504423, PMCID: PMC6855141, DOI: 10.1093/eurheartj/ehz592.
- Oikonomou EK, Antoniades C. The role of adipose tissue in cardiovascular health and disease. Nature Reviews Cardiology 2018, 16: 83-99. PMID: 30287946, DOI: 10.1038/s41569-018-0097-6.
- Oikonomou EK, Marwan M, Desai MY, Mancio J, Alashi A, Centeno E, Thomas S, Herdman L, Kotanidis CP, Thomas KE, Griffin BP, Flamm SD, Antonopoulos AS, Shirodaria C, Sabharwal N, Deanfield J, Neubauer S, Hopewell JC, Channon KM, Achenbach S, Antoniades C. Non-invasive detection of coronary inflammation using computed tomography and prediction of residual cardiovascular risk (the CRISP CT study): a post-hoc analysis of prospective outcome data. The Lancet 2018, 392: 929-939. PMID: 30170852, PMCID: PMC6137540, DOI: 10.1016/s0140-6736(18)31114-0.
- Holste G, Oikonomou EK, Khera R. AI-Enabled Echocardiography Interpretation With Multitask Deep Learning-Reply. JAMA 2025, 334: 1954-1955. PMID: 41160035, DOI: 10.1001/jama.2025.16627.
- Dhingra LS, Croon PM, Batinica B, Aminorroaya A, Pedroso AF, Oikonomou EK, Khera R. Reliability of Artificial Intelligence-enhanced Electrocardiography. MedRxiv 2025 PMID: 41282699, DOI: 10.1101/2025.11.04.25339526.
- Croon P, Dhingra L, Biswas D, Oikonomou E, Khera R. Phenotypic Selectivity of Artificial Intelligence–Enhanced Electrocardiography in Cardiovascular Diagnosis and Risk Prediction. Circulation 2025, 152: 1282-1294. PMID: 40888124, PMCID: PMC12573264, DOI: 10.1161/circulationaha.125.076279.
- Kagiyama N, Tokodi M, Hathaway QA, Arnaout R, Davies R, Dey D, Duchateau N, Fraser AG, Goto S, Jamthikar AD, Lam CSP, Oikonomou EK, Ouyang D, Pandey A, Poterucha TJ, Raisi-Estabragh Z, Strom JB, Zhang Q, Yanamala N, Sengupta PP. PRIME 2.0: Proposed Requirements for Cardiovascular Imaging-Related Multimodal-AI Evaluation: An Updated Checklist. JACC Cardiovasc Imaging 2025 PMID: 40892627, DOI: 10.1016/j.jcmg.2025.08.004.
- Duffy G, Oikonomou E, Easton N, Usuku H, Patel J, Katsumata Y, Yamasawa D, Stern L, Goto S, Tsujita K, Cheng P, Khera R, Ahmad F, Ouyang D. International Validation of Echocardiographic Artificial Intelligence Amyloid Detection Algorithm. JACC Advances 2025, 102067. PMID: 40965401, DOI: 10.1016/j.jacadv.2025.102067.
- Oikonomou E, Khera R. Artificial intelligence-guided point-of-care ultrasonography for cardiomyopathy detection – Authors' reply. The Lancet Digital Health 2025, 7: 100893. PMID: 40769793, DOI: 10.1016/j.landig.2025.100893.
- Sangha V, Dhingra L, Aminorroaya A, Croon P, Sikand N, Sen S, Martinez M, Maron M, Krumholz H, Asselbergs F, Oikonomou E, Khera R. Identification of hypertrophic cardiomyopathy on electrocardiographic images with deep learning. Nature Cardiovascular Research 2025, 4: 991-1000. PMID: 40696040, DOI: 10.1038/s44161-025-00685-3.
- Artificial Intelligence–Enabled Prediction of Heart Failure Risk From Single-Lead ElectrocardiogramsDhingra L, Aminorroaya A, Pedroso A, Khunte A, Sangha V, McIntyre D, Chow C, Asselbergs F, Brant L, Barreto S, Ribeiro A, Krumholz H, Oikonomou E, Khera R. Artificial Intelligence–Enabled Prediction of Heart Failure Risk From Single-Lead Electrocardiograms. JAMA Cardiology 2025, 10: 574-584. PMID: 40238120, PMCID: PMC12004248, DOI: 10.1001/jamacardio.2025.0492.
- From Pixels to Patterns: Radiomic Subphenotyping of Left Ventricular Hypertrophy on EchocardiographyOikonomou E, Khera R. From Pixels to Patterns: Radiomic Subphenotyping of Left Ventricular Hypertrophy on Echocardiography. Circulation Cardiovascular Imaging 2025, 18: e018291. PMID: 40326361, DOI: 10.1161/circimaging.125.018291.
- Thangaraj P, Oikonomou E, Dhingra L, Aminorroaya A, Jayaram R, Suchard M, Khera R. Computational Phenomapping of Randomized Clinical Trial Participants to Enable Assessment of Their Real-World Representativeness and Personalized Inference. Circulation Cardiovascular Quality And Outcomes 2025, 18: e011306. PMID: 40261065, PMCID: PMC12203226, DOI: 10.1161/circoutcomes.124.011306.
- Aminorroaya A, Dhingra L, Pedroso A, Shankar S, Coppi A, Khunte A, Foppa M, Brant L, Barreto S, Ribeiro A, Krumholz H, Oikonomou E, Khera R. Development and multinational validation of an ensemble deep learning algorithm for detecting and predicting structural heart disease using noisy single-lead electrocardiograms. European Heart Journal - Digital Health 2025, 6: 554-566. PMID: 40703117, PMCID: PMC12282373, DOI: 10.1093/ehjdh/ztaf034.
- Shankar S, Dhingra L, Aminorroaya A, Adejumo P, Nadkarni G, Xu H, Brandt C, Oikonomou E, Pedroso A, Khera R. Automated transformation of unstructured cardiovascular diagnostic reports into structured datasets using sequentially deployed large language models. European Heart Journal - Digital Health 2025, 6: 783-796. PMID: 40703108, PMCID: PMC12282380, DOI: 10.1093/ehjdh/ztaf030.
- Dhingra L, Aminorroaya A, Sangha V, Pedroso A, Shankar S, Coppi A, Foppa M, Brant L, Barreto S, Ribeiro A, Krumholz H, Oikonomou E, Khera R. Ensemble Deep Learning Algorithm for Structural Heart Disease Screening Using Electrocardiographic Images PRESENT SHD. Journal Of The American College Of Cardiology 2025, 85: 1302-1313. PMID: 40139886, PMCID: PMC12199746, DOI: 10.1016/j.jacc.2025.01.030.
- Aminorroaya A, Oikonomou E, Biswas D, Jastreboff A, Khera R. Effects of Tirzepatide in Type 2 Diabetes Individual Variation and Relationship to Cardiometabolic Outcomes. Journal Of The American College Of Cardiology 2025, 85: 1858-1872. PMID: 40368575, PMCID: PMC12186526, DOI: 10.1016/j.jacc.2025.03.516.
- Aminorroaya A, Dhingra L, Oikonomou E, Khera R. Evaluation of a Machine Learning-Guided Strategy for Elevated Lipoprotein(a) Screening in Health Systems. Circulation Genomic And Precision Medicine 2025, 18: e004632. PMID: 39846171, PMCID: PMC11835527, DOI: 10.1161/circgen.124.004632.
- Dhingra L, Aminorroaya A, Sangha V, Pedroso A, Asselbergs F, Brant L, Barreto S, Ribeiro A, Krumholz H, Oikonomou E, Khera R. Heart failure risk stratification using artificial intelligence applied to electrocardiogram images: a multinational study. European Heart Journal 2025, 46: 1044-1053. PMID: 39804243, PMCID: PMC12086686, DOI: 10.1093/eurheartj/ehae914.
- Dhingra L, Sangha V, Aminorroaya A, Bryde R, Gaballa A, Ali A, Mehra N, Krumholz H, Sen S, Kramer C, Martinez M, Desai M, Oikonomou E, Khera R. A Multicenter Evaluation of the Impact of Therapies on Deep Learning-Based Electrocardiographic Hypertrophic Cardiomyopathy Markers. The American Journal Of Cardiology 2024, 237: 35-40. PMID: 39581517, PMCID: PMC11761372, DOI: 10.1016/j.amjcard.2024.11.028.
- Oikonomou E, Khera R. Expanding artificial intelligence to understudied populations: congenital heart disease as the next frontier. European Heart Journal 2024, 46: 869-871. PMID: 39523016, PMCID: PMC11879170, DOI: 10.1093/eurheartj/ehae737.
- Dhingra LS, Aminorroaya A, Sangha V, Pedroso AF, Shankar SV, Coppi A, Foppa M, Brant LC, Barreto SM, Ribeiro ALP, Krumholz HM, Oikonomou EK, Khera R. An Ensemble Deep Learning Algorithm for Structural Heart Disease Screening Using Electrocardiographic Images: PRESENT SHD. MedRxiv 2024 PMID: 39417095, DOI: 10.1101/2024.10.06.24314939.
- Aminorroaya A, Dhingra LS, Pedroso Camargos A, Vasisht Shankar S, Coppi A, Khunte A, Foppa M, Brant LC, Barreto SM, Ribeiro ALP, Krumholz HM, Oikonomou EK, Khera R. Development and Multinational Validation of an Ensemble Deep Learning Algorithm for Detecting and Predicting Structural Heart Disease Using Noisy Single-lead Electrocardiograms. MedRxiv 2024 PMID: 39417103, DOI: 10.1101/2024.10.07.24314974.
- Shankar SV, Dhingra LS, Aminorroaya A, Adejumo P, Nadkarni GN, Xu H, Brandt C, Oikonomou EK, Pedroso AF, Khera R. Automated Transformation of Unstructured Cardiovascular Diagnostic Reports into Structured Datasets Using Sequentially Deployed Large Language Models. MedRxiv 2024 PMID: 39417094, DOI: 10.1101/2024.10.08.24315035.
- Thangaraj P, Benson S, Oikonomou E, Asselbergs F, Khera R. Cardiovascular care with digital twin technology in the era of generative artificial intelligence. European Heart Journal 2024, 45: 4808-4821. PMID: 39322420, PMCID: PMC11638093, DOI: 10.1093/eurheartj/ehae619.
- Thangaraj PM, Shankar SV, Huang S, Nadkarni GN, Mortazavi BJ, Oikonomou EK, Khera R. A Novel Digital Twin Strategy to Examine the Implications of Randomized Clinical Trials for Real-World Populations. MedRxiv 2024 PMID: 38585929, DOI: 10.1101/2024.03.25.24304868.
- Oikonomou EK, Sangha V, Shankar SV, Coppi A, Krumholz HM, Nasir K, Miller EJ, Gallegos-Kattan C, Al-Kindi S, Khera R. Tracking the pre-clinical progression of transthyretin amyloid cardiomyopathy using artificial intelligence-enabled electrocardiography and echocardiography. MedRxiv 2024 PMID: 39252891, DOI: 10.1101/2024.08.25.24312556.
- Oikonomou E, Khera R. Designing medical artificial intelligence systems for global use: focus on interoperability, scalability, and accessibility. Hellenic Journal Of Cardiology 2024, 81: 9-17. PMID: 39025234, DOI: 10.1016/j.hjc.2024.07.003.
- Holste G, Oikonomou E, Mortazavi B, Wang Z, Khera R. Efficient deep learning-based automated diagnosis from echocardiography with contrastive self-supervised learning. Communications Medicine 2024, 4: 133. PMID: 38971887, PMCID: PMC11227494, DOI: 10.1038/s43856-024-00538-3.
- Oikonomou EK, Vaid A, Holste G, Coppi A, McNamara RL, Baloescu C, Krumholz HM, Wang Z, Apakama DJ, Nadkarni GN, Khera R. Artificial intelligence-guided detection of under-recognized cardiomyopathies on point-of-care cardiac ultrasound: a multi-center study. MedRxiv 2024 PMID: 38559021, DOI: 10.1101/2024.03.10.24304044.
- Aminorroaya A, Dhingra LS, Camargos AP, Shankar SV, Khunte A, Sangha V, Sen S, McNamara RL, Haynes N, Oikonomou EK, Khera R. Study Protocol for the Artificial Intelligence-Driven Evaluation of Structural Heart Diseases Using Wearable Electrocardiogram (ID-SHD). MedRxiv 2024 PMID: 38562867, DOI: 10.1101/2024.03.18.24304477.
- L’Italien G, Oikonomou E, Khera R, Potashman M, Beiner M, Maclaine G, Schmahmann J, Perlman S, Coric V. Video-Based Kinematic Analysis of Movement Quality in a Phase 3 Clinical Trial of Troriluzole in Adults with Spinocerebellar Ataxia: A Post Hoc Analysis. Neurology And Therapy 2024, 13: 1287-1301. PMID: 38814532, PMCID: PMC11263303, DOI: 10.1007/s40120-024-00625-6.
- Chan K, Wahome E, Tsiachristas A, Antonopoulos A, Patel P, Lyasheva M, Kingham L, West H, Oikonomou E, Volpe L, Mavrogiannis M, Nicol E, Mittal T, Halborg T, Kotronias R, Adlam D, Modi B, Rodrigues J, Screaton N, Kardos A, Greenwood J, Sabharwal N, De Maria G, Munir S, McAlindon E, Sohan Y, Tomlins P, Siddique M, Kelion A, Shirodaria C, Pugliese F, Petersen S, Blankstein R, Desai M, Gersh B, Achenbach S, Libby P, Neubauer S, Channon K, Deanfield J, Antoniades C, Consortium O, Thomas S, Denton J, Farral R, Taylor C, Qin W, Kasongo M, Anthony S, Banning A, Xie C, Kharbanda R, Pritchard A, Halborg T, Syed N, Fry S, Mathers C, Rose A, Hudson G, Bajaj A, Das I, Deshpande A, Rao P, Lawday D, Mirsadraee S, Hudson B, Berry C, Marwan M, Maurovich-Horvat P, He G, Lin W, Fan L, Takahashi N, Kondo H, Dai N, Ge J, Koo B, Guglielmo M, Pontone G, Huck D, Benedek T, Rajani R, Vilic D, Aljazzaf H, Mun M, Benedetti G, Preston R, Raisi-Estabragh Z, Connolly D, Sharma V, Grenfell R, Bradlow W, Schmitt M, Serfaty F, Gottlieb I, Neves M, Newby D, Dweck M, Hatem S, Redheuil A, Benetos G, Beer M, Granillo G, Selvanayagam J, Lopez-Jimenez F, De Bosscher R, Tavildari A, Figtree G, Danad I, Shantouf R, Kietselaer B, Tousoulis D, Dangas G, Mehta N, Kontanidis C, Kunadian V, Fairbairn T. Inflammatory risk and cardiovascular events in patients without obstructive coronary artery disease: the ORFAN multicentre, longitudinal cohort study. The Lancet 2024, 403: 2606-2618. PMID: 38823406, PMCID: PMC11664027, DOI: 10.1016/s0140-6736(24)00596-8.
- Dhingra LS, Aminorroaya A, Camargos AP, Khunte A, Sangha V, McIntyre D, Chow CK, Asselbergs FW, Brant LC, Barreto SM, Ribeiro ALP, Krumholz HM, Oikonomou EK, Khera R. Using Artificial Intelligence to Predict Heart Failure Risk from Single-lead Electrocardiographic Signals: A Multinational Assessment. MedRxiv 2024 PMID: 38854022, DOI: 10.1101/2024.05.27.24307952.
- Thangaraj PM, Oikonomou EK, Dhingra LS, Aminorroaya A, Jayaram R, Suchard MA, Khera R. Computational Phenomapping of Randomized Clinical Trials to Enable Assessment of their Real-world Representativeness and Personalized Inference. MedRxiv 2024 PMID: 38798457, DOI: 10.1101/2024.05.15.24306285.
- Aminorroaya A, Dhingra L, Oikonomou E, Saadatagah S, Thangaraj P, Vasisht Shankar S, Spatz E, Khera R. Development and multinational validation of an algorithmic strategy for high Lp(a) screening. Nature Cardiovascular Research 2024, 3: 558-566. PMID: 39195936, PMCID: PMC12190734, DOI: 10.1038/s44161-024-00469-1.
- Oikonomou E, Aminorroaya A, Dhingra L, Partridge C, Velazquez E, Desai N, Krumholz H, Miller E, Khera R. Real-world evaluation of an algorithmic machine-learning-guided testing approach in stable chest pain: a multinational, multicohort study. European Heart Journal - Digital Health 2024, 5: 303-313. PMID: 38774380, PMCID: PMC11104476, DOI: 10.1093/ehjdh/ztae023.
- Dhingra LS, Aminorroaya A, Sangha V, Camargos AP, Asselbergs FW, Brant LC, Barreto SM, Ribeiro ALP, Krumholz HM, Oikonomou EK, Khera R. Scalable Risk Stratification for Heart Failure Using Artificial Intelligence applied to 12-lead Electrocardiographic Images: A Multinational Study. MedRxiv 2024 PMID: 38633808, DOI: 10.1101/2024.04.02.24305232.
- Oikonomou E, Khera R. Leveraging the Full Potential of Wearable Devices in Cardiomyopathies. Journal Of Cardiac Failure 2024, 30: 964-966. PMID: 38452997, DOI: 10.1016/j.cardfail.2024.02.011.
- Khunte A, Sangha V, Oikonomou EK, Dhingra LS, Aminorroaya A, Coppi A, Shankar SV, Mortazavi BJ, Bhatt DL, Krumholz HM, Nadkarni GN, Vaid A, Khera R. Automated Diagnostic Reports from Images of Electrocardiograms at the Point-of-Care. MedRxiv 2024 PMID: 38405776, DOI: 10.1101/2024.02.17.24302976.
- Sangha V, Khunte A, Holste G, Mortazavi B, Wang Z, Oikonomou E, Khera R. Biometric contrastive learning for data-efficient deep learning from electrocardiographic images. Journal Of The American Medical Informatics Association 2024, 31: 855-865. PMID: 38269618, PMCID: PMC10990541, DOI: 10.1093/jamia/ocae002.
- Thangaraj PM, Shankar SV, Oikonomou EK, Khera R. RCT-Twin-GAN Generates Digital Twins of Randomized Control Trials Adapted to Real-world Patients to Enhance their Inference and Application. MedRxiv 2023 PMID: 38106089, DOI: 10.1101/2023.12.06.23299464.
- Shankar SV, Oikonomou EK, Khera R. CarDS-Plus ECG Platform: Development and Feasibility Evaluation of a Multiplatform Artificial Intelligence Toolkit for Portable and Wearable Device Electrocardiograms. MedRxiv 2023 PMID: 37873174, DOI: 10.1101/2023.10.02.23296404.
- Oikonomou E, Khera R. Machine learning in precision diabetes care and cardiovascular risk prediction. Cardiovascular Diabetology 2023, 22: 259. PMID: 37749579, PMCID: PMC10521578, DOI: 10.1186/s12933-023-01985-3.
- Aminorroaya A, Dhingra L, Nargesi A, Oikonomou E, Krumholz H, Khera R. Use of Smart Devices to Track Cardiovascular Health Goals in the United States. JACC Advances 2023, 2: 100544. PMID: 38094515, PMCID: PMC10718569, DOI: 10.1016/j.jacadv.2023.100544.
- Khunte A, Sangha V, Oikonomou E, Dhingra L, Aminorroaya A, Mortazavi B, Coppi A, Brandt C, Krumholz H, Khera R. Detection of left ventricular systolic dysfunction from single-lead electrocardiography adapted for portable and wearable devices. Npj Digital Medicine 2023, 6: 124. PMID: 37433874, PMCID: PMC10336107, DOI: 10.1038/s41746-023-00869-w.
- Dhingra L, Aminorroaya A, Oikonomou E, Nargesi A, Wilson F, Krumholz H, Khera R. Use of Wearable Devices in Individuals With or at Risk for Cardiovascular Disease in the US, 2019 to 2020. JAMA Network Open 2023, 6: e2316634. PMID: 37285157, PMCID: PMC10248745, DOI: 10.1001/jamanetworkopen.2023.16634.
- Nargesi A, Clark C, Aminorroaya A, Chen L, Liu M, Reddy A, Amodeo S, Oikonomou E, Suchard M, McGuire D, Lin Z, Inzucchi S, Khera R. Persistence on Novel Cardioprotective Antihyperglycemic Therapies in the United States. The American Journal Of Cardiology 2023, 196: 89-98. PMID: 37012183, PMCID: PMC11007258, DOI: 10.1016/j.amjcard.2023.03.002.
- Kotanidis CP, Xie C, Alexander D, Rodrigues JCL, Burnham K, Mentzer A, O’Connor D, Knight J, Siddique M, Lockstone H, Thomas S, Kotronias R, Oikonomou EK, Badi I, Lyasheva M, Shirodaria C, Lumley SF, Constantinides B, Sanderson N, Rodger G, Chau KK, Lodge A, Tsakok M, Gleeson F, Adlam D, Rao P, Indrajeet D, Deshpande A, Bajaj A, Hudson BJ, Srivastava V, Farid S, Krasopoulos G, Sayeed R, Ho LP, Neubauer S, Newby DE, Channon KM, Deanfield J, Antoniades C, Consortium C, Ahern D, Ai Z, Ainsworth M, Allan C, Allcock A, Angus B, Ansari M, Arancibia-Cárcamo C, Aschenbrenner D, Attar M, Baillie J, Barnes E, Bashford-Rogers R, Bashyal A, Beer S, Berridge G, Beveridge A, Bibi S, Bicanic T, Blackwell L, Bowness P, Brent A, Brown A, Broxholme J, Buck D, Burnham K, Byrne H, Camara S, Ferreira I, Charles P, Chen W, Chen Y, Chong A, Clutterbuck E, Coles M, Conlon C, Cornall R, Cribbs A, Curion F, Davenport E, Davidson N, Davis S, Dendrou C, Dequaire J, Dib L, Docker J, Dold C, Dong T, Downes D, Drakesmith H, Dunachie S, Duncan D, Eijsbouts C, Esnouf R, Espinosa A, Etherington R, Fairfax B, Fairhead R, Fang H, Fassih S, Felle S, Mendoza M, Ferreira R, Fischer R, Foord T, Forrow A, Frater J, Fries A, Sanchez V, Garner L, Geeves C, Georgiou D, Godfrey L, Golubchik T, Vazquez M, Green A, Harper H, Harrington H, Heilig R, Hester S, Hill J, Hinds C, Hird C, Ho L, Hoekzema R, Hollis B, Hughes J, Hutton P, Jackson-Wood M, Jainarayanan A, James-Bott A, Jansen K, Jeffery K, Jones E, Jostins L, Kerr G, Kim D, Klenerman P, Knight J, Kumar V, Sharma P, Kurupati P, Kwok A, Lee A, Linder A, Lockett T, Lonie L, Lopopolo M, Lukoseviciute M, Luo J, Marinou S, Marsden B, Martinez J, Matthews P, Mazurczyk M, McGowan S, McKechnie S, Mead A, Mentzer A, Mi Y, Monaco C, Montadon R, Napolitani G, Nassiri I, Novak A, O'Brien D, O'Connor D, O'Donnell D, Ogg G, Overend L, Park I, Pavord I, Peng Y, Penkava F, Pinho M, Perez E, Pollard A, Powrie F, Psaila B, Quan T, Repapi E, Revale S, Silva-Reyes L, Richard J, Rich-Griffin C, Ritter T, Rollier C, Rowland M, Ruehle F, Salio M, Sansom S, Peres R, Delgado A, Sauka-Spengler T, Schwessinger R, Scozzafava G, Screaton G, Seigal A, Semple M, Sergeant M, Karali C, Sims D, Skelly D, Slawinski H, Sobrinodiaz A, Sousos N, Stafford L, Stockdale L, Strickland M, Sumray O, Sun B, Taylor C, Taylor S, Taylor A, Thongjuea S, Thraves H, Todd J, Tomic A, Tong O, Trebes A, Trzupek D, Tucci F, Turtle L, Udalova I, Uhlig H, van Grinsven E, Vendrell I, Verheul M, Voda A, Wang G, Wang L, Wang D, Watkinson P, Watson R, Weinberger M, Whalley J, Witty L, Wray K, Xue L, Yeung H, Yin Z, Young R, Youngs J, Zhang P, Zurke Y, investigators O, Banning A, Antonopoulos A, Bajaj A, Kelion A, Deshpande A, Kardos A, Hudson B, Koo B, Shirodaria C, Xie C, Kotanidis C, Mahon C, Berry C, Adlam D, Newby D, Connolly D, Scaletta D, Alexander D, Nicol E, McAlindon E, Oikonomou E, Pugliese F, Pontone G, Benedetti G, He G, West H, Kondo H, Benedek I, Das I, Deanfield J, Graby J, Greenwood J, Rodrigues J, Ge J, Channon K, Fabritz L, Fan L, Kingham L, Guglielmo M, Lyasheva M, Schmitt M, Beer M, Anderson M, Desai M, Marwan M, Takahashi N, Mehta N, Dai N, Screaton N, Sabharwal N, Maurovich-Horvat P, Rao P, Kotronias R, Kharbanda R, Preston R, Wood R, Blankstein R, Rajani R, Mirsadraee S, Munir S, Thomas S, Neubauer S, Klömpken S, Petersen S, Achenbach S, Anthony S, Mak S, Mittal T, Benedek T, Sharma V, Lin W. Constructing custom-made radiotranscriptomic signatures of vascular inflammation from routine CT angiograms: a prospective outcomes validation study in COVID-19. The Lancet Digital Health 2022, 4: e705-e716. PMID: 36038496, PMCID: PMC9417284, DOI: 10.1016/s2589-7500(22)00132-7.
- Kwan JM, Oikonomou EK, Henry ML, Sinusas AJ. Multimodality Advanced Cardiovascular and Molecular Imaging for Early Detection and Monitoring of Cancer Therapy-Associated Cardiotoxicity and the Role of Artificial Intelligence and Big Data. Frontiers In Cardiovascular Medicine 2022, 9: 829553. PMID: 35369354, PMCID: PMC8964995, DOI: 10.3389/fcvm.2022.829553.
- Oikonomou EK, Suchard MA, McGuire DK, Khera R. Phenomapping-Derived Tool to Individualize the Effect of Canagliflozin on Cardiovascular Risk in Type 2 Diabetes. Diabetes Care 2022, 45: 965-974. PMID: 35120199, PMCID: PMC9016734, DOI: 10.2337/dc21-1765.
- Bellumkonda L, Oikonomou EK, Hsueh C, Maulion C, Testani J, Patel J. The impact of induction therapy on mortality and treated rejection in cardiac transplantation: A retrospective study. The Journal Of Heart And Lung Transplantation 2022, 41: 482-491. PMID: 35094919, DOI: 10.1016/j.healun.2022.01.008.
- Antonopoulos A, Angelopoulos A, Papanikolaou P, Simantiris S, Oikonomou E, Vamvakaris K, Koumpoura A, Farmaki M, Trivella M, Vlachopoulos C, Tsioufis K, Antoniades C, Tousoulis D. Biomarkers of Vascular Inflammation for Cardiovascular Risk Prognostication A Meta-Analysis. JACC Cardiovascular Imaging 2021, 15: 460-471. PMID: 34801448, DOI: 10.1016/j.jcmg.2021.09.014.
- Antoniades C, Oikonomou E. Artificial intelligence in cardiovascular imaging—principles, expectations, and limitations. European Heart Journal 2021, 45: 1322-1326. PMID: 34557898, PMCID: PMC11015951, DOI: 10.1093/eurheartj/ehab678.
- Feher A, Boutagy NE, Oikonomou EK, Liu YH, Miller EJ, Sinusas AJ, Hinchcliff M. Association Between Impaired Myocardial Flow Reserve on 82Rubidium Positron Emission Tomography Imaging and Adverse Events in Patients With Autoimmune Rheumatic Disease. Circulation Cardiovascular Imaging 2021, 14: e012208. PMID: 34503339, PMCID: PMC8475774, DOI: 10.1161/circimaging.120.012208.
- Oikonomou EK, Antonopoulos AS, Schottlander D, Marwan M, Mathers C, Tomlins P, Siddique M, Klüner LV, Shirodaria C, Mavrogiannis MC, Thomas S, Fava A, Deanfield J, Channon KM, Neubauer S, Desai MY, Achenbach S, Antoniades C. Standardized measurement of coronary inflammation using cardiovascular computed tomography: integration in clinical care as a prognostic medical device. Cardiovascular Research 2021, 117: 2677-2690. PMID: 34450625, DOI: 10.1093/cvr/cvab286.
- Kondo H, Akoumianakis I, Badi I, Akawi N, Kotanidis CP, Polkinghorne M, Stadiotti I, Sommariva E, Antonopoulos AS, Carena MC, Oikonomou EK, Reus EM, Sayeed R, Krasopoulos G, Srivastava V, Farid S, Chuaiphichai S, Shirodaria C, Channon KM, Casadei B, Antoniades C. Effects of canagliflozin on human myocardial redox signalling: clinical implications. European Heart Journal 2021, 42: 4947-4960. PMID: 34293101, PMCID: PMC8691807, DOI: 10.1093/eurheartj/ehab420.
- Feher A, Boutagy NE, Oikonomou EK, Thorn S, Liu YH, Miller EJ, Sinusas AJ, Hinchcliff M. Impaired Myocardial Flow Reserve on 82Rubidium Positron Emission Tomography/Computed Tomography in Patients With Systemic Sclerosis. The Journal Of Rheumatology 2021, 48: 1574-1582. PMID: 34266986, PMCID: PMC10275580, DOI: 10.3899/jrheum.210040.
- Gallegos C, Oikonomou EK, Grimshaw A, Gulati M, Young BD, Miller EJ. Non-steroidal treatment of cardiac sarcoidosis: A systematic review. IJC Heart & Vasculature 2021, 34: 100782. PMID: 33997256, PMCID: PMC8105294, DOI: 10.1016/j.ijcha.2021.100782.
- Klüner LV, Oikonomou EK, Antoniades C. Assessing Cardiovascular Risk by Using the Fat Attenuation Index in Coronary CT Angiography. Radiology Cardiothoracic Imaging 2021, 3: e200563. PMID: 33778665, PMCID: PMC7977699, DOI: 10.1148/ryct.2021200563.
- Nolan M, Oikonomou E, Silversides C, Hines M, Thompson K, Campbell B, Amir E, Maxwell C, Thavendiranathan P. Impact of Cancer Therapy-Related Cardiac Dysfunction on Risk of Heart Failure in Pregnancy. JACC CardioOncology 2020, 2: 153-162. PMID: 34396225, PMCID: PMC8352036, DOI: 10.1016/j.jaccao.2020.04.007.
- Akoumianakis I, Badi I, Douglas G, Chuaiphichai S, Herdman L, Akawi N, Margaritis M, Antonopoulos AS, Oikonomou EK, Psarros C, Galiatsatos N, Tousoulis D, Kardos A, Sayeed R, Krasopoulos G, Petrou M, Schwahn U, Wohlfart P, Tennagels N, Channon KM, Antoniades C. Insulin-induced vascular redox dysregulation in human atherosclerosis is ameliorated by dipeptidyl peptidase 4 inhibition. Science Translational Medicine 2020, 12 PMID: 32350133, PMCID: PMC7212010, DOI: 10.1126/scitranslmed.aav8824.
- Oikonomou EK, Siddique M, Antoniades C. Artificial intelligence in medical imaging: A radiomic guide to precision phenotyping of cardiovascular disease. Cardiovascular Research 2020, 116: 2040-2054. PMID: 32090243, PMCID: PMC7585409, DOI: 10.1093/cvr/cvaa021.
- Oikonomou EK. Molecular imaging to guide precision diagnosis and prevention of cancer therapeutics-related cardiac dysfunction. Expert Review Of Molecular Diagnostics 2020, 20: 355-358. PMID: 31944137, DOI: 10.1080/14737159.2020.1717336.
- Nolan M, Oikonomou EK, Silversides CK, Hines MR, Thompson KA, Campbell BA, Amir E, Maxwell C, Thavendiranathan P. J Am Coll Cardiol CardioOnc. 2020 Jun, 2 (2) 153-162.
- Oikonomou EK, Kokkinidis DG, Kampaktsis PN, Amir EA, Marwick TH, Gupta D, Thavendiranathan P. Assessment of Prognostic Value of Left Ventricular Global Longitudinal Strain for Early Prediction of Chemotherapy-Induced Cardiotoxicity. JAMA Cardiology 2019, 4: 1007-1018. PMID: 31433450, PMCID: PMC6705141, DOI: 10.1001/jamacardio.2019.2952.
- Oikonomou EK, West HW, Antoniades C. Cardiac Computed Tomography. Arteriosclerosis Thrombosis And Vascular Biology 2019, 39: 2207-2219. PMID: 31510795, DOI: 10.1161/atvbaha.119.312899.
- Elnabawi YA, Oikonomou EK, Dey AK, Mancio J, Rodante JA, Aksentijevich M, Choi H, Keel A, Erb-Alvarez J, Teague HL, Joshi AA, Playford MP, Lockshin B, Choi AD, Gelfand JM, Chen MY, Bluemke DA, Shirodaria C, Antoniades C, Mehta NN. Association of Biologic Therapy With Coronary Inflammation in Patients With Psoriasis as Assessed by Perivascular Fat Attenuation Index. JAMA Cardiology 2019, 4: 885-891. PMID: 31365032, PMCID: PMC6669789, DOI: 10.1001/jamacardio.2019.2589.
- Antonopoulos AS, Odutayo A, Oikonomou EK, Trivella M, Petrou M, Collins GS, Antoniades C, group S, Akoumianakis I, Channon K, Herdman L, Margaritis M, Neubauer S, Thomas S, Fremes S, Karkhanis R, Rade J, Fukui T, Nishida H, Takanashi S, Hwang H, Kim K, Mannacio L, Mannacio V, Nakano J, Perrault L, Kardos A, Okabayashi H, Tousoulis D, Kelion A, Sabharwal N, Krasopoulos G, Sayeed R, Taggart D. Development of a risk score for early saphenous vein graft failure: An individual patient data meta-analysis. Journal Of Thoracic And Cardiovascular Surgery 2019, 160: 116-127.e4. PMID: 31606176, PMCID: PMC7322547, DOI: 10.1016/j.jtcvs.2019.07.086.
- Papanastasiou CA, Kokkinidis DG, Jonnalagadda AK, Oikonomou EK, Kampaktsis PN, Garcia MJ, Myerson SG, Karamitsos TD. Meta-Analysis of Transthoracic Echocardiography Versus Cardiac Magnetic Resonance for the Assessment of Aortic Regurgitation After Transcatheter Aortic Valve Implantation. The American Journal Of Cardiology 2019, 124: 1246-1251. PMID: 31466694, DOI: 10.1016/j.amjcard.2019.07.036.
- Papanastasiou CA, Kokkinidis DG, Kampaktsis PN, Bikakis I, Cunha DK, Oikonomou EK, Greenwood JP, Garcia MJ, Karamitsos TD. The Prognostic Role of Late Gadolinium Enhancement in Aortic Stenosis A Systematic Review and Meta-Analysis. JACC Cardiovascular Imaging 2019, 13: 385-392. PMID: 31326491, DOI: 10.1016/j.jcmg.2019.03.029.
- Chuy K, Oikonomou EK, Postow MA, Callahan MK, Chapman PB, Shoushtari AN, Neilan TG, Fradley MG, Ramanathan LV, Wolchok JD, Steingart RM, Gupta D. Myocarditis Surveillance in Patients with Advanced Melanoma on Combination Immune Checkpoint Inhibitor Therapy: The Memorial Sloan Kettering Cancer Center Experience. The Oncologist 2019, 24: e196-e197. PMID: 30910868, PMCID: PMC6516118, DOI: 10.1634/theoncologist.2019-0040.
- Mancio J, Oikonomou EK, Antoniades C. Perivascular adipose tissue and coronary atherosclerosis. Heart 2018, 104: 1654. PMID: 29853488, DOI: 10.1136/heartjnl-2017-312324.
- Kokkinidis DG, Papanastasiou CA, Jonnalagadda AK, Oikonomou EK, Theochari CA, Palaiodimos L, Karvounis HI, Armstrong EJ, Faillace RT, Giannakoulas G. The predictive value of baseline pulmonary hypertension in early and long term cardiac and all-cause mortality after transcatheter aortic valve implantation for patients with severe aortic valve stenosis: A systematic review and meta-analysis. Cardiovascular Revascularization Medicine 2018, 19: 859-867. PMID: 29724516, DOI: 10.1016/j.carrev.2018.03.015.
- Theochari CA, Michalopoulos G, Oikonomou EK, Giannopoulos S, Doulamis IP, Villela MA, Kokkinidis DG. Heart transplantation versus left ventricular assist devices as destination therapy or bridge to transplantation for 1-year mortality: a systematic review and meta-analysis. Annals Of Cardiothoracic Surgery 2018, 7: 3-11. PMID: 29492379, PMCID: PMC5827119, DOI: 10.21037/acs.2017.09.18.
- Tsilimigras DI, Oikonomou EK, Moris D, Schizas D, Economopoulos KP, Mylonas KS. Stem Cell Therapy for Congenital Heart Disease. Circulation 2017, 136: 2373-2385. PMID: 29229621, DOI: 10.1161/circulationaha.117.029607.
- Oikonomou EK. Clinical and translational science in cardiovascular research: highlights from the American Heart Association Scientific Sessions 2017. Cardiovascular Research 2017, 114: e6-e8. PMID: 29202178, DOI: 10.1093/cvr/cvx233.
- Papanastasiou CA, Kokkinidis DG, Oikonomou EK, Mantziaris VG, Foley TR, Karamitsos TD, Waldo SW, Armstrong EJ. Pregnancy associated plasma protein-A as a prognostic biomarker of all-cause mortality and cardiovascular events in patients presenting with chest pain: a systematic review. Biomarkers 2017, 23: 1-9. PMID: 29144175, DOI: 10.1080/1354750x.2017.1397194.
- Toutouzas K, Skoumas J, Koutagiar I, Benetos G, Pianou N, Georgakopoulos A, Galanakos S, Antonopoulos A, Drakopoulou M, Oikonomou EK, Kafouris P, Athanasiadis E, Metaxas M, Spyrou G, Pallantza Z, Galiatsatos N, Aggeli C, Antoniades C, Keramida G, Peters AM, Anagnostopoulos CD, Tousoulis D. Vascular inflammation and metabolic activity in hematopoietic organs and liver in familial combined hyperlipidemia and heterozygous familial hypercholesterolemia. Journal Of Clinical Lipidology 2017, 12: 33-43. PMID: 29174439, DOI: 10.1016/j.jacl.2017.10.019.
- Kampaktsis PN, Oikonomou EK, Y. Choi D, Cheung JW. Efficacy of ganglionated plexi ablation in addition to pulmonary vein isolation for paroxysmal versus persistent atrial fibrillation: a meta-analysis of randomized controlled clinical trials. Journal Of Interventional Cardiac Electrophysiology 2017, 50: 253-260. PMID: 28887742, DOI: 10.1007/s10840-017-0285-z.
- Oikonomou EK, Antoniades C. Immunometabolic Regulation of Vascular Redox State: The Role of Adipose Tissue. Antioxidants & Redox Signaling 2017, 29: 313-336. PMID: 28657335, DOI: 10.1089/ars.2017.7017.
- Antonopoulos AS, Sanna F, Sabharwal N, Thomas S, Oikonomou EK, Herdman L, Margaritis M, Shirodaria C, Kampoli AM, Akoumianakis I, Petrou M, Sayeed R, Krasopoulos G, Psarros C, Ciccone P, Brophy CM, Digby J, Kelion A, Uberoi R, Anthony S, Alexopoulos N, Tousoulis D, Achenbach S, Neubauer S, Channon KM, Antoniades C. Detecting human coronary inflammation by imaging perivascular fat. Science Translational Medicine 2017, 9 PMID: 28701474, DOI: 10.1126/scitranslmed.aal2658.
- Kokkinidis DG, Oikonomou EK, Papanastasiou CA, Theochari CA, Giannakoulas G. Methodological Remarks in the Meta-Analysis on the Impact of Baseline Pulmonary Hypertension on Post-Transcatheter Aortic Valve Implantation Outcomes. The American Journal Of Cardiology 2017, 120: 513-514. PMID: 28554487, DOI: 10.1016/j.amjcard.2017.04.032.
- Margaritis M, Sanna F, Lazaros G, Akoumianakis I, Patel S, Antonopoulos AS, Duke C, Herdman L, Psarros C, Oikonomou EK, Shirodaria C, Petrou M, Sayeed R, Krasopoulos G, Lee R, Tousoulis D, Channon KM, Antoniades C. Predictive value of telomere length on outcome following acute myocardial infarction: evidence for contrasting effects of vascular vs. blood oxidative stress. European Heart Journal 2017, 38: 3094-3104. PMID: 28444175, PMCID: PMC5837455, DOI: 10.1093/eurheartj/ehx177.
- Taggart DP, Amin S, Djordjevic J, Oikonomou EK, Thomas S, Kampoli AM, Sabharwal N, Antoniades C, Krasopoulos G. A prospective study of external stenting of saphenous vein grafts to the right coronary artery: the VEST II study. European Journal Of Cardio-Thoracic Surgery 2017, 51: 952-958. PMID: 28379404, DOI: 10.1093/ejcts/ezw438.
- De Maria GL, Alkhalil M, Oikonomou EK, Wolfrum M, Choudhury RP, Banning AP. Role of deferred stenting in patients with ST elevation myocardial infarction treated with primary percutaneous coronary intervention: A systematic review and meta‐analysis. Journal Of Interventional Cardiology 2017, 30: 264-273. PMID: 28370496, DOI: 10.1111/joic.12380.
- Lazaros G, Antonopoulos AS, Oikonomou EK, Vasileiou P, Oikonomou E, Stroumpouli E, Karavidas A, Antoniades C, Tousoulis D. Prognostic implications of epicardial fat volume quantification in acute pericarditis. European Journal Of Clinical Investigation 2016, 47: 129-136. PMID: 27931089, DOI: 10.1111/eci.12711.
- Oikonomou EK, Repanas TI, Papanastasiou C, Kokkinidis DG, Miligkos M, Feher A, Gupta D, Kampaktsis PN. The effect of in-hospital acquired thrombocytopenia on the outcome of patients with acute coronary syndromes: A systematic review and meta-analysis. Thrombosis Research 2016, 147: 64-71. PMID: 27689317, PMCID: PMC5515466, DOI: 10.1016/j.thromres.2016.09.026.