Catherine Bingchan Xie, MD, PhD
Dermatology
Titles
- Clinical Fellow T32
Education & Training
- MDYale School of Medicine (2022)
- PhDYale University, Immunobiology (2020)
- MPhilUniversity of Cambridge, Trinity College, Clinical Science – Translational Medicine and Therapeutics (2014)
- BSCalifornia Institute of Technology, Bioengineering, English minor (2013)
Languages Spoken
- 官話 / 官话 (Chinese-Mandarin)
- English
Additional Information
Honors & Recognitions
- MD-PhD Graduation Prize Award: Yale School of Medicine (2022)
- Best Graduate Student Poster Award: Yale Immunobiology Department (2018), (2019)
- FOCIS Center of Excellence Trainee Award: Federation of Clinical Immunology Studies (FOCIS) (2018)
- NRSA Pre-Doctoral Dual-Degree Training Fellowship Grant (F30): National Institute of Allergy and Infectious Diseases (NIAID), NIH (2018)
- Gates Cambridge Scholar: Gates Cambridge Trust and Cambridge University (2013)
Publications
- Hodelin C, Xie C, Katini S, Johnston M, Cohen J. Sustained remission of guttate psoriasis flares with short-term interleukin-23 inhibition: A case series. Journal Of The American Academy Of Dermatology 2025, 93: 1582-1584. PMID: 40825398, DOI: 10.1016/j.jaad.2025.08.017.
- Jiang R, Zhou A, Ko C, Girardi M, Hanly A, Xie C, Preda-Naumescu A, Gehlhausen J, Tomayko M. Atypical bullous systemic lupus erythematosus with features of linear IgA bullous dermatosis. JAAD Case Reports 2025, 58: 74-76. PMID: 40129457, PMCID: PMC11930652, DOI: 10.1016/j.jdcr.2024.12.040.
- Xie C, Stryjewska B, McNiff J, Shiferaw B. Erythema nodosum leprosum after allergen immunotherapy as initial presentation of lepromatous leprosy treated with novel multidrug regimen. JAAD Case Reports 2023, 41: 77-80. PMID: 37916038, PMCID: PMC10615896, DOI: 10.1016/j.jdcr.2023.09.012.
- Xie CB, Ring N, Damsky W, McNiff JM, Olino K, Odell I. Squamous cell carcinoma arising in long-standing necrobiosis lipoidica treated with radical resection and split-thickness skin graft. JAAD Case Reports 2021, 19: 90-93. PMID: 35024397, PMCID: PMC8724883, DOI: 10.1016/j.jdcr.2021.11.005.
- Xie CB, Kidacki M, Ring N, Panse G, Leventhal JS. Iatrogenic calcinosis cutis from extravasated phosphate-containing solution treated with topical sodium thiosulfate. JAAD Case Reports 2021, 17: 31-33. PMID: 34692964, PMCID: PMC8517711, DOI: 10.1016/j.jdcr.2021.09.013.
- Xie CB, Zhou J, Mackay S, Pober JS. Complement-activated human endothelial cells stimulate increased polyfunctionality in alloreactive T cells. American Journal Of Transplantation 2021, 21: 1902-1909. PMID: 33415805, PMCID: PMC8096653, DOI: 10.1111/ajt.16485.
- Xie CB, Cowper S, Odell ID. Morphea after Borrelia-induced facial nerve palsy. Journal Of Scleroderma And Related Disorders 2020, 6: 111-113. PMID: 35382252, PMCID: PMC8922639, DOI: 10.1177/2397198320956892.
- Xie CB, Jiang B, Qin L, Tellides G, Kirkiles-Smith NC, Jane-wit D, Pober JS. Complement activated interferon-γ-primed human endothelium transpresents interleukin-15 to CD8+ T cells. Journal Of Clinical Investigation 2020, 130: 3437-3452. PMID: 32191642, PMCID: PMC7324183, DOI: 10.1172/jci135060.
- Xie CB, Jane-Wit D, Pober JS. Complement Membrane Attack Complex New Roles, Mechanisms of Action, and Therapeutic Targets. American Journal Of Pathology 2020, 190: 1138-1150. PMID: 32194049, PMCID: PMC7280757, DOI: 10.1016/j.ajpath.2020.02.006.
- Baltazar T, Merola J, Catarino C, Xie C, Kirkiles-Smith N, Lee V, Hotta S, Dai G, Xu X, Ferreira FC, Saltzman WM, Pober JS, Karande P. Three Dimensional Bioprinting of a Vascularized and Perfusable Skin Graft Using Human Keratinocytes, Fibroblasts, Pericytes, and Endothelial Cells. Tissue Engineering Part A 2019, 26: 227-238. PMID: 31672103, PMCID: PMC7476394, DOI: 10.1089/ten.tea.2019.0201.
- Liu L, Fang C, Fu W, Jiang B, Li G, Qin L, Rosenbluth J, Gong G, Xie CB, Yoo P, Tellides G, Pober JS, Jane-Wit D. Endothelial Cell–Derived Interleukin-18 Released During Ischemia Reperfusion Injury Selectively Expands T Peripheral Helper Cells to Promote Alloantibody Production. Circulation 2019, 141: 464-478. PMID: 31744330, PMCID: PMC7035199, DOI: 10.1161/circulationaha.119.042501.
- Merola J, Reschke M, Pierce RW, Qin L, Spindler S, Baltazar T, Manes TD, Lopez-Giraldez F, Li G, Bracaglia LG, Xie C, Kirkiles-Smith N, Saltzman WM, Tietjen GT, Tellides G, Pober JS. Progenitor-derived human endothelial cells evade alloimmunity by CRISPR/Cas9-mediated complete ablation of MHC expression. JCI Insight 2019, 4 PMID: 31527312, PMCID: PMC6824302, DOI: 10.1172/jci.insight.129739.
- Fang C, Manes TD, Liu L, Liu K, Qin L, Li G, Tobiasova Z, Kirkiles-Smith NC, Patel M, Merola J, Fu W, Liu R, Xie C, Tietjen GT, Nigrovic PA, Tellides G, Pober JS, Jane-wit D. ZFYVE21 is a complement-induced Rab5 effector that activates non-canonical NF-κB via phosphoinosotide remodeling of endosomes. Nature Communications 2019, 10: 2247. PMID: 31113953, PMCID: PMC6529429, DOI: 10.1038/s41467-019-10041-2.
- Xie CB, Qin L, Li G, Fang C, Kirkiles-Smith NC, Tellides G, Pober JS, Jane-Wit D. Complement Membrane Attack Complexes Assemble NLRP3 Inflammasomes Triggering IL-1 Activation of IFN-γ–Primed Human Endothelium. Circulation Research 2019, 124: 1747-1759. PMID: 31170059, PMCID: PMC6557295, DOI: 10.1161/circresaha.119.314845.
- Liu R, Merola J, Manes TD, Qin L, Tietjen GT, López-Giráldez F, Broecker V, Fang C, Xie C, Chen PM, Kirkiles-Smith NC, Jane-Wit D, Pober JS. Interferon-γ converts human microvascular pericytes into negative regulators of alloimmunity through induction of indoleamine 2,3-dioxygenase 1. JCI Insight 2018, 3: e97881. PMID: 29515027, PMCID: PMC5922286, DOI: 10.1172/jci.insight.97881.
- Xie CB, Haris Shaikh L, Garg S, Tanriver G, Teo AE, Zhou J, Maniero C, Zhao W, Kang S, Silverman RB, Azizan EA, Brown MJ. Regulation of aldosterone secretion by Cav1.3. Scientific Reports 2016, 6: 24697. PMID: 27098837, PMCID: PMC4876952, DOI: 10.1038/srep24697.
Titles
- Clinical Fellow T32
Education & Training
- MDYale School of Medicine (2022)
- PhDYale University, Immunobiology (2020)
- MPhilUniversity of Cambridge, Trinity College, Clinical Science – Translational Medicine and Therapeutics (2014)
- BSCalifornia Institute of Technology, Bioengineering, English minor (2013)
Languages Spoken
- 官話 / 官话 (Chinese-Mandarin)
- English
Additional Information
Honors & Recognitions
- MD-PhD Graduation Prize Award: Yale School of Medicine (2022)
- Best Graduate Student Poster Award: Yale Immunobiology Department (2018), (2019)
- FOCIS Center of Excellence Trainee Award: Federation of Clinical Immunology Studies (FOCIS) (2018)
- NRSA Pre-Doctoral Dual-Degree Training Fellowship Grant (F30): National Institute of Allergy and Infectious Diseases (NIAID), NIH (2018)
- Gates Cambridge Scholar: Gates Cambridge Trust and Cambridge University (2013)
Publications
- Hodelin C, Xie C, Katini S, Johnston M, Cohen J. Sustained remission of guttate psoriasis flares with short-term interleukin-23 inhibition: A case series. Journal Of The American Academy Of Dermatology 2025, 93: 1582-1584. PMID: 40825398, DOI: 10.1016/j.jaad.2025.08.017.
- Jiang R, Zhou A, Ko C, Girardi M, Hanly A, Xie C, Preda-Naumescu A, Gehlhausen J, Tomayko M. Atypical bullous systemic lupus erythematosus with features of linear IgA bullous dermatosis. JAAD Case Reports 2025, 58: 74-76. PMID: 40129457, PMCID: PMC11930652, DOI: 10.1016/j.jdcr.2024.12.040.
- Xie C, Stryjewska B, McNiff J, Shiferaw B. Erythema nodosum leprosum after allergen immunotherapy as initial presentation of lepromatous leprosy treated with novel multidrug regimen. JAAD Case Reports 2023, 41: 77-80. PMID: 37916038, PMCID: PMC10615896, DOI: 10.1016/j.jdcr.2023.09.012.
- Xie CB, Ring N, Damsky W, McNiff JM, Olino K, Odell I. Squamous cell carcinoma arising in long-standing necrobiosis lipoidica treated with radical resection and split-thickness skin graft. JAAD Case Reports 2021, 19: 90-93. PMID: 35024397, PMCID: PMC8724883, DOI: 10.1016/j.jdcr.2021.11.005.
- Xie CB, Kidacki M, Ring N, Panse G, Leventhal JS. Iatrogenic calcinosis cutis from extravasated phosphate-containing solution treated with topical sodium thiosulfate. JAAD Case Reports 2021, 17: 31-33. PMID: 34692964, PMCID: PMC8517711, DOI: 10.1016/j.jdcr.2021.09.013.
- Xie CB, Zhou J, Mackay S, Pober JS. Complement-activated human endothelial cells stimulate increased polyfunctionality in alloreactive T cells. American Journal Of Transplantation 2021, 21: 1902-1909. PMID: 33415805, PMCID: PMC8096653, DOI: 10.1111/ajt.16485.
- Xie CB, Cowper S, Odell ID. Morphea after Borrelia-induced facial nerve palsy. Journal Of Scleroderma And Related Disorders 2020, 6: 111-113. PMID: 35382252, PMCID: PMC8922639, DOI: 10.1177/2397198320956892.
- Xie CB, Jiang B, Qin L, Tellides G, Kirkiles-Smith NC, Jane-wit D, Pober JS. Complement activated interferon-γ-primed human endothelium transpresents interleukin-15 to CD8+ T cells. Journal Of Clinical Investigation 2020, 130: 3437-3452. PMID: 32191642, PMCID: PMC7324183, DOI: 10.1172/jci135060.
- Xie CB, Jane-Wit D, Pober JS. Complement Membrane Attack Complex New Roles, Mechanisms of Action, and Therapeutic Targets. American Journal Of Pathology 2020, 190: 1138-1150. PMID: 32194049, PMCID: PMC7280757, DOI: 10.1016/j.ajpath.2020.02.006.
- Baltazar T, Merola J, Catarino C, Xie C, Kirkiles-Smith N, Lee V, Hotta S, Dai G, Xu X, Ferreira FC, Saltzman WM, Pober JS, Karande P. Three Dimensional Bioprinting of a Vascularized and Perfusable Skin Graft Using Human Keratinocytes, Fibroblasts, Pericytes, and Endothelial Cells. Tissue Engineering Part A 2019, 26: 227-238. PMID: 31672103, PMCID: PMC7476394, DOI: 10.1089/ten.tea.2019.0201.
- Liu L, Fang C, Fu W, Jiang B, Li G, Qin L, Rosenbluth J, Gong G, Xie CB, Yoo P, Tellides G, Pober JS, Jane-Wit D. Endothelial Cell–Derived Interleukin-18 Released During Ischemia Reperfusion Injury Selectively Expands T Peripheral Helper Cells to Promote Alloantibody Production. Circulation 2019, 141: 464-478. PMID: 31744330, PMCID: PMC7035199, DOI: 10.1161/circulationaha.119.042501.
- Merola J, Reschke M, Pierce RW, Qin L, Spindler S, Baltazar T, Manes TD, Lopez-Giraldez F, Li G, Bracaglia LG, Xie C, Kirkiles-Smith N, Saltzman WM, Tietjen GT, Tellides G, Pober JS. Progenitor-derived human endothelial cells evade alloimmunity by CRISPR/Cas9-mediated complete ablation of MHC expression. JCI Insight 2019, 4 PMID: 31527312, PMCID: PMC6824302, DOI: 10.1172/jci.insight.129739.
- Fang C, Manes TD, Liu L, Liu K, Qin L, Li G, Tobiasova Z, Kirkiles-Smith NC, Patel M, Merola J, Fu W, Liu R, Xie C, Tietjen GT, Nigrovic PA, Tellides G, Pober JS, Jane-wit D. ZFYVE21 is a complement-induced Rab5 effector that activates non-canonical NF-κB via phosphoinosotide remodeling of endosomes. Nature Communications 2019, 10: 2247. PMID: 31113953, PMCID: PMC6529429, DOI: 10.1038/s41467-019-10041-2.
- Xie CB, Qin L, Li G, Fang C, Kirkiles-Smith NC, Tellides G, Pober JS, Jane-Wit D. Complement Membrane Attack Complexes Assemble NLRP3 Inflammasomes Triggering IL-1 Activation of IFN-γ–Primed Human Endothelium. Circulation Research 2019, 124: 1747-1759. PMID: 31170059, PMCID: PMC6557295, DOI: 10.1161/circresaha.119.314845.
- Liu R, Merola J, Manes TD, Qin L, Tietjen GT, López-Giráldez F, Broecker V, Fang C, Xie C, Chen PM, Kirkiles-Smith NC, Jane-Wit D, Pober JS. Interferon-γ converts human microvascular pericytes into negative regulators of alloimmunity through induction of indoleamine 2,3-dioxygenase 1. JCI Insight 2018, 3: e97881. PMID: 29515027, PMCID: PMC5922286, DOI: 10.1172/jci.insight.97881.
- Xie CB, Haris Shaikh L, Garg S, Tanriver G, Teo AE, Zhou J, Maniero C, Zhao W, Kang S, Silverman RB, Azizan EA, Brown MJ. Regulation of aldosterone secretion by Cav1.3. Scientific Reports 2016, 6: 24697. PMID: 27098837, PMCID: PMC4876952, DOI: 10.1038/srep24697.