Neurogenetics

This information is useful for children, adults, and older adults
Two people are supporting a person with a neurogenetics diagnosis.

Many autoimmune diseases including Alzheimer's disease, ALS, multiple sclerosis, and others have genetic underpinnings. What if scientists could use genomic sequencing on patients to figure out which genetic factors are responsible for their illness? 

Neurogenetics is a new field of scientific research that uses recent advances in genome sequencing in order to better understand the cause of brain and nerve disorders. The Yale Medicine Neurogenetics Program offers whole exome sequencing—an affordable and efficient technique of pinpointing genetic factors of inherited disease. That can help patients determine the extent to which their genetic material plays a role in their condition.

Neurogenetics is also helping to advance the concept of personalized clinical care. With a comprehensive understanding of a patient’s genetic profile and medical history, physicians can create highly tailored treatment programs for each patient. For example, a cancer patient can now receive genome analysis of the specific mutations within a tumor. Based on those results, doctors can then assess whether cancer medications (which can be highly toxic) will even work before administering the drug.