The Zest Study - Zymfentra
- Study IRB#:2000041354
- Last Updated:10/26/2026
The purpose of this research study is to evaluate the safety and efficacy of Zymfentra in a real-world setting. A total of approximately 200 people aged 18 and older at about 20 institutions will take part in this study.
You will be asked to complete questionnaires, provide stool samples and allow collection of your medical record data. Your participation will last approximately 1 year.
- Age18 years and older
- GenderBoth
Contact Us
For more information about this study, including how to volunteer, contact:
Elizabeth Ruggiero
- Phone Number: 203-785-4576
Help Us Discover!
You can help our team find trials you might be eligible for by creating a volunteer profile in MyChart. To get started, create a volunteer profile, or contact helpusdiscover@yale.edu, or call 877-978-8343 for more information.
Study Location
- Yale University
Eligibility Criteria
Adult patients, age 18 years or older, with CD, UC or IBDU, who are either starting Zymfentra at week 10 (IFX-dyyb) in the setting of standard-of-care initiation with intravenous IFX originator or IFX biosimilars induction therapy at weeks 0,2,6 or switching from intravenous IFX originator or IFX biosimilars during maintenance therapy to Zymfentra (IFX-dyyb).
Anticipation that the patient will be followed by the participating center for the next 12 months.
