Brain Changes and Cannabis Use Study
- Study HIC#:2000032181
 
- Last Updated:11/03/2025
 
Brain Changes and Cannabis Use Study
Adult participants needed aged 18 to 75 who use cannabis/ marijuana for a brain imaging study to determine whether brain imaging changes in individuals diagnosed with cannabis use disorder (CUDs) or if there is improvement with at least 4 weeks of confirmed abstinence from cannabis, in comparison to healthy controls (HCs). Study compensation up to $5,075.
- Eligibility criteria:
 
Ages: 18 to 75
Study involves: Screening visit, brain imaging sessions, at least 4 weeks of abstinence from cannabis
Pays up to: $5,075
Inclusion Criteria:
- Daily cannabis users (at least 30 times per month, with a 2+ year history and 1000+ lifetime uses).
 - Must test positive for cannabis (and negative for other drugs).
 - Diagnosed with moderate or greater Cannabis Use Disorder (DSM-5).
 - Cannabis must be the primary drug of choice.
 - Willing to set a quit date during screening.
 - Generally healthy, with no unstable medical conditions.
 - No major psychiatric disorders like schizophrenia or bipolar disorder.
 - Not taking medications that affect brain chemistry related to the study.
 - Limited other drug use in the past 3 months.
 - Must agree to use birth control (if applicable).
 - Willing and able to follow study procedures.
 
The Study Team contact name, telephone number, and email: Coordinator Shannon Zeilman, phone: 203-626-1105, email: yalecannabisresearch@yale.edu
Study Sponsor: NIH
HIC number: HIC #2000032181
- Age18 years - 75 years
 - GenderBoth
 
Contact Us
For more information about this study, including how to volunteer, contact:
Kimberlee Forselius-Bielen
Help Us Discover!
You can help our team find trials you might be eligible for by creating a volunteer profile in MyChart. To get started, create a volunteer profile, or contact helpusdiscover@yale.edu, or call +18779788343 for more information.
Eligibility Criteria
Eligibility criteria:
Ages: 18 to 75
Study involves: Screening visit, brain imaging sessions, at least 4 weeks of abstinence from cannabis
Pays up to: $5,075
Inclusion Criteria:
- Daily cannabis users (at least 30 times per month, with a 2+ year history and 1000+ lifetime uses).
 - Must test positive for cannabis (and negative for other drugs).
 - Diagnosed with moderate or greater Cannabis Use Disorder (DSM-5).
 - Cannabis must be the primary drug of choice.
 - Willing to set a quit date during screening.
 - Generally healthy, with no unstable medical conditions.
 - No major psychiatric disorders like schizophrenia or bipolar disorder.
 - Not taking medications that affect brain chemistry related to the study.
 - Limited other drug use in the past 3 months.
 - Must agree to use birth control (if applicable).
 - Willing and able to follow study procedures.