Brain Changes and Cannabis Use Study

Brain Changes and Cannabis Use Study

Adult participants needed aged 18 to 75 who use cannabis/ marijuana for a brain imaging study to determine whether brain imaging changes in individuals diagnosed with cannabis use disorder (CUDs) or if there is improvement with at least 4 weeks of confirmed abstinence from cannabis, in comparison to healthy controls (HCs). Study compensation up to $5,075.

• Eligibility criteria:

Ages: 18 to 75

Study involves: Screening visit, brain imaging sessions, at least 4 weeks of abstinence from cannabis

Pays up to: $5,075

Inclusion Criteria:

• Daily cannabis users (at least 30 times per month, with a 2+ year history and 1000+ lifetime uses).
• Must test positive for cannabis (and negative for other drugs).
• Diagnosed with moderate or greater Cannabis Use Disorder (DSM-5).
• Cannabis must be the primary drug of choice.
• Willing to set a quit date during screening.
• Generally healthy, with no unstable medical conditions.
• No major psychiatric disorders like schizophrenia or bipolar disorder.
• Not taking medications that affect brain chemistry related to the study.
• Limited other drug use in the past 3 months.
• Must agree to use birth control (if applicable).
• Willing and able to follow study procedures.

The Study Team contact name, telephone number, and email: Shannon Zeilman at shannon.zeilman@yale.edu or yalecannabisresearch@yale.edu

Study Sponsor: NIH

HIC number: HIC #2000032181