Restless Legs Syndrome: Melanocortins and Melanocortin Receptor Mutation
- Study IRB#:1507016119
- Last Updated:10/22/2026
The study aims to clarify the underlying biological mechanisms of restless legs syndrome (RLS). We are studying the melanocortin and endorphin hormones in the cereborspinal fluid, blood and skin in patients with RLS and in healthy controls.
In this portion of the study, we are measuring levels assessing ferritin and melanocortin hormones in the skin and blood. Participation entails one 30 minute visit, completion of questionnaires, a blood draw and two small 3mm skin punch biopsies.
- Age18 years - 79 years
- GenderBoth
Contact Us
For more information about this study, including how to volunteer, contact:
Yuanyu Chen
- Phone Number: 203-785-2285
Help Us Discover!
You can help our team find trials you might be eligible for by creating a volunteer profile in MyChart. To get started, create a volunteer profile, or contact helpusdiscover@yale.edu, or call 877-978-8343 for more information.
Study Location
- Yale University
Eligibility Criteria
- Between 18-79 years old
- Male or female
- No blood thinner, No opioids, no steroids.
- As we are studying skin, participants must be caucasian.
