Cardiovascular Genomics and Imaging for Precision Medicine in Aortic Disease
- Study IRB#:2000041429
- Last Updated:10/28/2026
The purpose of this study is to improve our understanding of the causes of cardiovascular disease and to develop better ways to provide patients with a diagnosis and a prognosis and to discover better ways to treat patients.
Individuals that can participate are those that have aortic disease (also termed “aortopathy”) and/or aortic valve disease, one of their family members has aortic disease and/or aortic valve disease, those that are genetically at risk for developing aortic disease and/or aortic valve disease, and those that are not affected by aortic disease and/or aortic valve disease and are having tissue removed during a surgical procedure.
Study procedures will include:
(1) Collection of samples from a blood draw, cheek swab, or saliva
(2) Collection of leftover tissue if you have a heart surgery or other procedure that involves removal of tissue
(3) Collection of family history information
(4) Medical history review.
- Age1 month and older
- GenderBoth
Contact Us
For more information about this study, including how to volunteer, contact:
Ermena Refugjati
Help Us Discover!
You can help our team find trials you might be eligible for by creating a volunteer profile in MyChart. To get started, create a volunteer profile, or contact helpusdiscover@yale.edu, or call 877-978-8343 for more information.
Study Location
- Yale University
Eligibility Criteria
Eligibility Criteria:
Those that have aortic disease (also termed “aortopathy”) and/or aortic valve disease, one of their family members has aortic disease and/or aortic valve disease, those that are genetically at risk for developing aortic disease and/or aortic valve disease, and those that are not affected by aortic disease and/or aortic valve disease and are having tissue removed during a surgical procedure.
