Imaging alpha-synuclein in the brain using PET
- Study HIC#:2000037211
- Last Updated:11/10/2025
The purpose of this study is to determine the biodistribution, metabolism, excretion, and brain uptake of 11C-M503. The goal of this radiotracer is to quantify alpha-synuclein that is abnormally deposited in the brain of people with Parkinson’s disease (PD), multiple system atrophy (MSA), and progressive supranuclear palsy (PSP), as well as non-Parkinsonism volunteers. We will be using an imaging technique called PET (Positron Emission Tomography), which can track the movement of the radiotracer in the brain. This is a multi-center human subjects project and participants will be recruited from several collaborating sites.
Contact Us
For more information about this study, including how to volunteer, contact:
Mark Dias
- Phone Number: 1-203-737-6128
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You can help our team find trials you might be eligible for by creating a volunteer profile in MyChart. To get started, create a volunteer profile, or contact helpusdiscover@yale.edu, or call +18779788343 for more information.
Eligibility Criteria
Adult male and female subjects, aged 40-85, who have been clinically diagnosed with PD, MSA, PSP, or are healthy controls who meet the inclusion criteria, and who do not meet any of the exclusion criteria will be eligible for enrollment into the study.
