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Screening for Breast and Lung Cancers
Transcript
- 00:00 --> 00:03Funding for Yale Cancer Answers is
- 00:03 --> 00:06provided by Smilow Cancer Hospital.
- 00:06 --> 00:07Welcome to Yale Cancer
- 00:07 --> 00:08Answers with your host
- 00:08 --> 00:11Doctor Anees Chagpar.
- 00:11 --> 00:13Yale Cancer Answers features the latest information on
- 00:13 --> 00:15cancer care by welcoming oncologists and
- 00:15 --> 00:18specialists who are on the forefront of
- 00:18 --> 00:20the battle to fight cancer. This week,
- 00:20 --> 00:21it's a conversation about screening for
- 00:21 --> 00:23breast and lung cancers with Doctor
- 00:23 --> 00:24Ilana Richman.
- 00:24 --> 00:26Dr Richman is an assistant
- 00:26 --> 00:27professor in internal medicine
- 00:27 --> 00:29at the Yale School of Medicine,
- 00:29 --> 00:32where Doctor Chagpar is a
- 00:32 --> 00:34professor of surgical oncology.
- 00:34 --> 00:35So Ilana,
- 00:35 --> 00:36maybe we can start off by you
- 00:36 --> 00:38telling us a little bit about
- 00:38 --> 00:40yourself and what it is you do.
- 00:40 --> 00:43I'm a general internist.
- 00:43 --> 00:46I see patients in primary care.
- 00:46 --> 00:49And it was actually my clinical
- 00:49 --> 00:50practice as a general internist
- 00:50 --> 00:53that led me to get interested in
- 00:53 --> 00:55prevention and cancer screening.
- 00:55 --> 00:56It's kind of a core part of what
- 00:56 --> 00:58we do in primary care is to try
- 00:58 --> 01:00to keep our patients healthy.
- 01:00 --> 01:01It's part of what drew me to
- 01:01 --> 01:03primary care in the 1st place,
- 01:03 --> 01:05and also what has led to my research
- 01:05 --> 01:07interests in cancer screening
- 01:08 --> 01:10so so tell us a little bit more
- 01:10 --> 01:12about that so you know one of the
- 01:12 --> 01:14things that I think our listeners
- 01:14 --> 01:16will be very familiar with is the.
- 01:16 --> 01:20Fact that you know there are so many cancers,
- 01:20 --> 01:22some of which you can screen for
- 01:22 --> 01:24some of which you can't screen for.
- 01:24 --> 01:26And even the ones that you can
- 01:26 --> 01:28screen for it seems like the
- 01:28 --> 01:30screening guidelines keep changing.
- 01:30 --> 01:33So how do you approach screening from
- 01:33 --> 01:36a primary care kind of standpoint?
- 01:37 --> 01:40So those are great questions.
- 01:40 --> 01:42I'll start with the first,
- 01:42 --> 01:44which is why is it that some cancers
- 01:44 --> 01:47we can screen for and others we can't?
- 01:47 --> 01:49The answer to that really has to do with
- 01:49 --> 01:51lots of different aspects of what it means
- 01:51 --> 01:54to have a successful screening test in
- 01:54 --> 01:56order for screening to be successful,
- 01:56 --> 01:59we need to be able to reliably detect
- 01:59 --> 02:02a cancer we need to be able to find
- 02:02 --> 02:04it at a point when it's treatable and
- 02:04 --> 02:06we need to have good treatments for
- 02:06 --> 02:08that disease. So there are a few.
- 02:08 --> 02:11Cancer is that fit that profile.
- 02:11 --> 02:12The ones that we commonly screened
- 02:12 --> 02:14for are good examples, breast cancer,
- 02:14 --> 02:17colorectal cancer, cervical cancer, and more.
- 02:17 --> 02:18Recently lung cancer.
- 02:18 --> 02:20But there are many others that don't.
- 02:20 --> 02:22For a variety of reasons,
- 02:22 --> 02:23it's sort of too hard to find them.
- 02:23 --> 02:25The cancers generally tend to be aggressive,
- 02:25 --> 02:27and so screening once a year actually
- 02:27 --> 02:30wouldn't even be enough or we don't have
- 02:30 --> 02:32good treatments even for early stage disease.
- 02:32 --> 02:34The last piece I'll say is that
- 02:34 --> 02:36cancers need to be common enough,
- 02:36 --> 02:39or or you need to identify a high enough
- 02:39 --> 02:41risk population to make screening worthwhile.
- 02:42 --> 02:43So there may be some cancers,
- 02:43 --> 02:44for example that are quite rare and
- 02:44 --> 02:46we would just never consider screening
- 02:46 --> 02:48every patient who comes along with them,
- 02:48 --> 02:49because just makes no sense to
- 02:49 --> 02:50go looking for attention.
- 02:50 --> 02:52It's extremely unlikely to be there,
- 02:52 --> 02:55so those are some of the features that
- 02:55 --> 02:59make screening reasonable to think
- 02:59 --> 03:03about in terms of why guidelines change.
- 03:03 --> 03:06It's a great question and tends to
- 03:06 --> 03:09have to do with. A couple things.
- 03:09 --> 03:12First is sometimes the evidence changes,
- 03:12 --> 03:15so lung cancer screening is a great example.
- 03:15 --> 03:17For years and years we had no effective
- 03:17 --> 03:19way to screen for lung cancer.
- 03:19 --> 03:21Lots of approaches to lung cancer
- 03:21 --> 03:23screening were studied, so for example,
- 03:23 --> 03:26can we take a test X ray of people
- 03:26 --> 03:28who smoke cigarettes every year
- 03:28 --> 03:29and look for lung cancer?
- 03:29 --> 03:31Can we examine the sputum that
- 03:31 --> 03:33kind of phlegm that people cough up
- 03:33 --> 03:34and look for signs of cancer?
- 03:34 --> 03:36Those approaches were studied and were
- 03:36 --> 03:38not successful, and so for a long time.
- 03:38 --> 03:40The recommendation was not to screen
- 03:40 --> 03:43using any of those modalities,
- 03:43 --> 03:44but.
- 03:44 --> 03:45In 2011,
- 03:45 --> 03:47a landmark study was published
- 03:47 --> 03:50that showed that we can effectively
- 03:50 --> 03:51use computed tomography,
- 03:51 --> 03:52which is CT scan the kind of test
- 03:53 --> 03:54where you lie down on a table and
- 03:54 --> 03:56get zipped through a donut takes a
- 03:56 --> 03:57very detailed picture of your chest.
- 03:57 --> 04:00We can use that to look for early
- 04:00 --> 04:02signs of lung cancer among people who
- 04:02 --> 04:04are high risk for developing lung cancer,
- 04:04 --> 04:06and in fact it works if we use it
- 04:06 --> 04:08annually for a number of years.
- 04:08 --> 04:11We tend to find lung cancers early
- 04:11 --> 04:12when they're treatable.
- 04:12 --> 04:16And we can actually successfully avert.
- 04:16 --> 04:18You know the risk of dying of
- 04:18 --> 04:19lung cancer for some people.
- 04:19 --> 04:21So in 2013 our recommendations
- 04:21 --> 04:24changed and slowly this technology
- 04:24 --> 04:26has percolated out into the community,
- 04:26 --> 04:30so sometimes recommendations change
- 04:30 --> 04:32in response to our scientific
- 04:32 --> 04:35understanding of what works.
- 04:35 --> 04:38And then lastly, I'll say that
- 04:38 --> 04:40sometimes recommendations change
- 04:40 --> 04:43because population health changes.
- 04:43 --> 04:44Colorectal cancer screening
- 04:44 --> 04:46is a good example of that.
- 04:46 --> 04:48We are using the same technologies
- 04:48 --> 04:49that we've used for collecting
- 04:49 --> 04:51cancer screening more or less
- 04:51 --> 04:53for the last 10 or 20 years,
- 04:53 --> 04:55or maybe even longer.
- 04:55 --> 04:57We use colonoscopy which is a test
- 04:57 --> 05:00where we use a camera to directly
- 05:00 --> 05:02look for early signs of colon cancer,
- 05:02 --> 05:04or we can use stool based test.
- 05:04 --> 05:06Sorry, look in the stool for signs of cancer,
- 05:06 --> 05:08but more recently we've understood
- 05:08 --> 05:10that actually the epidemiology
- 05:10 --> 05:12of colon cancer is changing.
- 05:12 --> 05:14Colon cancer seems to be more
- 05:14 --> 05:15common among younger adults,
- 05:15 --> 05:17and so we've actually lowered the
- 05:17 --> 05:19age at which we recommend colon
- 05:19 --> 05:21cancer screening for for adults.
- 05:21 --> 05:22So we used to say start at age
- 05:22 --> 05:2450 for average risk adults and
- 05:24 --> 05:26now we say start at age 45,
- 05:26 --> 05:27and that's in response.
- 05:27 --> 05:29Not to some new scientific understanding
- 05:29 --> 05:30about colon cancer screening,
- 05:30 --> 05:31but in response to changes in the
- 05:31 --> 05:33epidemiology of the disease itself,
- 05:33 --> 05:35so lots of reasons why
- 05:35 --> 05:36recommendations might change.
- 05:37 --> 05:40And then there are some diseases where
- 05:40 --> 05:42you know it depends on who you ask,
- 05:42 --> 05:45what the recommendations are and
- 05:45 --> 05:47and breast cancer seems to be
- 05:47 --> 05:49one that falls into that bucket.
- 05:49 --> 05:51Can you talk a little bit about that?
- 05:51 --> 05:54Because I think that that actually causes a
- 05:54 --> 05:57lot of confusion amongst the general public.
- 05:57 --> 06:00If they look at, for example,
- 06:00 --> 06:02the American Cancer Society guidelines,
- 06:02 --> 06:05they may be different from the US
- 06:05 --> 06:07Preventive Services Task Force.
- 06:07 --> 06:09From the American College of
- 06:09 --> 06:12Radiology from the American College
- 06:12 --> 06:14of Obstetrics and Gynecology.
- 06:14 --> 06:18So how do you kind of approach that?
- 06:18 --> 06:20Why are there differences,
- 06:20 --> 06:22and how can you help our listeners
- 06:22 --> 06:24to figure out which guidelines
- 06:24 --> 06:26they should be following?
- 06:27 --> 06:29I'll give you an example for
- 06:29 --> 06:30listeners that may not, you know,
- 06:30 --> 06:32know some of the nuances around these
- 06:32 --> 06:33guys 'cause they think it's helpful
- 06:33 --> 06:35to talk about some of the specifics
- 06:35 --> 06:36and give a sense of how the guidelines
- 06:36 --> 06:38might differ in primary care.
- 06:38 --> 06:39We often rely on guidelines put
- 06:39 --> 06:41out by a group called the US
- 06:41 --> 06:43Preventive Services Task Force,
- 06:43 --> 06:45which is a volunteer organization
- 06:45 --> 06:47of experts in medicine and public
- 06:47 --> 06:49health and that group, for example,
- 06:49 --> 06:52has recommended that for women in their 40s.
- 06:52 --> 06:53Women can consider getting screened
- 06:53 --> 06:56for breast cancer every other year,
- 06:56 --> 06:57and that should be a discussion with
- 06:57 --> 06:59their physician or their clinician about
- 06:59 --> 07:01the risks and benefits of screening.
- 07:01 --> 07:03But it's not sort of a strong
- 07:03 --> 07:04recommendation that women should
- 07:04 --> 07:06definitely get screened beginning
- 07:06 --> 07:09in the 50s between age 50 and 74.
- 07:09 --> 07:10There's a stronger recommendation that
- 07:10 --> 07:12women should be screened every other year.
- 07:12 --> 07:13In contrast,
- 07:13 --> 07:16the American Cancer Society guidelines say
- 07:16 --> 07:19women 40 to 44 can consider screening,
- 07:19 --> 07:21but beginning at 45 age 45.
- 07:21 --> 07:24Up to 55 women in that age group should
- 07:24 --> 07:26actually consider annual screening,
- 07:26 --> 07:28which is quite different than
- 07:28 --> 07:30saying maybe women 45 to 50 should
- 07:30 --> 07:32be screened every other year.
- 07:32 --> 07:34So why would accounts for the difference?
- 07:34 --> 07:36I would say it's sort of a different
- 07:36 --> 07:38approach to balancing benefit and
- 07:38 --> 07:40harm the US Preventive Services
- 07:40 --> 07:41Task Force looked at the guidelines
- 07:41 --> 07:43and say you know what?
- 07:43 --> 07:44In general women in their 40s are at
- 07:44 --> 07:46low risk for developing breast cancer,
- 07:46 --> 07:48and if we screen them in this population.
- 07:48 --> 07:50There's some incremental benefits.
- 07:50 --> 07:53A small number of women will have
- 07:53 --> 07:55a late stage breast cancer,
- 07:55 --> 07:55breast cancer,
- 07:55 --> 07:56death averted,
- 07:56 --> 07:58but many many more women will have
- 07:58 --> 07:59a false positive test.
- 07:59 --> 08:02They'll be some abnormality seen
- 08:02 --> 08:02on their mammogram.
- 08:02 --> 08:04That turns out to be nothing but
- 08:04 --> 08:06that woman is then put through
- 08:06 --> 08:07this experience of being told
- 08:07 --> 08:09that the mammogram is abnormal.
- 08:09 --> 08:10You might need additional imaging.
- 08:10 --> 08:12You might need a biopsy and you now
- 08:12 --> 08:14go through a few weeks where you
- 08:14 --> 08:17are worried that you might have a
- 08:17 --> 08:18breast cancer and that experiences.
- 08:18 --> 08:21Unpleasant to to put it mildly so you know,
- 08:21 --> 08:24I think it's sort of the way that two
- 08:24 --> 08:27people can look at the same situation
- 08:27 --> 08:28and see it slightly differently.
- 08:28 --> 08:31Different groups look at the same data,
- 08:31 --> 08:33and for some for some guideline
- 08:33 --> 08:34organizations they say hey,
- 08:34 --> 08:36our number one goal is to avert
- 08:36 --> 08:38breast cancer deaths and others
- 08:38 --> 08:40say we need to balance that with
- 08:40 --> 08:42the very real kind of burdens and
- 08:42 --> 08:44harms that come from screenings.
- 08:44 --> 08:45I think it's really,
- 08:45 --> 08:47you know how organizations.
- 08:47 --> 08:52Decide where the net benefit lies.
- 08:52 --> 08:53Getting back to patients,
- 08:53 --> 08:54I would say you know,
- 08:54 --> 08:58for women in their 40s and.
- 08:58 --> 09:00It's an opportunity to think
- 09:00 --> 09:01about what matters.
- 09:01 --> 09:02Some women,
- 09:02 --> 09:03I think in that age group would say,
- 09:03 --> 09:03hey,
- 09:03 --> 09:05you know I have seen other women go
- 09:05 --> 09:07through the experience of breast cancer,
- 09:07 --> 09:09and I never want to.
- 09:09 --> 09:11I never want to deal with a late
- 09:11 --> 09:13stage breast cancer and I would like
- 09:13 --> 09:15to do everything I can to avoid that.
- 09:15 --> 09:17And for those women, I think it for sure.
- 09:17 --> 09:19Makes sense to be screened.
- 09:19 --> 09:20Other women may have personal risk factors
- 09:20 --> 09:22that make it sensible to be screened.
- 09:22 --> 09:24You know, close relatives first,
- 09:24 --> 09:26you know mother or sisters who've
- 09:26 --> 09:28had breast cancer and their
- 09:28 --> 09:30personal risk is higher and they
- 09:30 --> 09:32may feel compelled to be screened.
- 09:32 --> 09:33You know other women might look
- 09:33 --> 09:34at the same situation and say,
- 09:34 --> 09:36you know what I feel healthy.
- 09:36 --> 09:37I don't have any specific risk
- 09:37 --> 09:39factors and for me it makes sense
- 09:39 --> 09:41to minimize the number of tests that
- 09:41 --> 09:42you know I have to go through and
- 09:42 --> 09:44I'll I'll start screen when I'm 50.
- 09:44 --> 09:45And that's also, I think,
- 09:45 --> 09:46a reasonable decision.
- 09:47 --> 09:49And so you know, it sounds like
- 09:49 --> 09:51women should really think about
- 09:51 --> 09:54what what is their personal risk,
- 09:54 --> 09:55what's important to them,
- 09:55 --> 09:57and talk to their doctor.
- 09:57 --> 10:00How does this intersect with?
- 10:00 --> 10:03You know, insurance companies and
- 10:03 --> 10:07governments who have to pay for these tests.
- 10:07 --> 10:11I mean, many plans would
- 10:11 --> 10:13cover preventative services.
- 10:13 --> 10:16But do they cover them?
- 10:16 --> 10:18Kind of based on one set of
- 10:18 --> 10:19guidelines versus another.
- 10:19 --> 10:20So for example,
- 10:20 --> 10:23if you are a 40 year old and you
- 10:23 --> 10:26decide I want to get a mammogram every
- 10:26 --> 10:27year because that's important to me,
- 10:27 --> 10:30I've had close friends who have
- 10:30 --> 10:31gone through the experience.
- 10:31 --> 10:34I never want to go through that,
- 10:34 --> 10:36even if I don't necessarily have
- 10:36 --> 10:39a personal family history myself,
- 10:39 --> 10:41or am necessarily at high risk,
- 10:41 --> 10:43but that fits.
- 10:43 --> 10:45Within some society guidelines
- 10:45 --> 10:47but not within others,
- 10:47 --> 10:49is that still covered by insurance?
- 10:49 --> 10:51The history of insurance coverage of
- 10:51 --> 10:53screening is actually really interesting
- 10:53 --> 10:55and I can tell you a little bit about
- 10:55 --> 10:57kind of the back story for context and
- 10:57 --> 11:01then we can talk about current policies.
- 11:01 --> 11:03Actually, you know when Medicare
- 11:03 --> 11:05was first signed into law in 1965?
- 11:05 --> 11:08Amazingly, Medicare didn't cover any
- 11:08 --> 11:11preventive services at all because it was
- 11:11 --> 11:14intended as a program to cover medical care
- 11:14 --> 11:17for the treatment and diagnosis of disease.
- 11:17 --> 11:18So prevention actually
- 11:18 --> 11:19doesn't fall into that right?
- 11:19 --> 11:21We're talking about healthy people.
- 11:21 --> 11:23But over the next few decades,
- 11:23 --> 11:26it became clear that things like vaccination,
- 11:26 --> 11:28cancer screening have benefit to
- 11:28 --> 11:31individuals and to the population health,
- 11:31 --> 11:32and these are really things that
- 11:32 --> 11:33ought to be covered under insurance.
- 11:33 --> 11:36So beginning in the late 80s and early 90s,
- 11:36 --> 11:37Medicare began to cover,
- 11:37 --> 11:38for example,
- 11:38 --> 11:40cervical cancer screening and
- 11:40 --> 11:41breast cancer screening,
- 11:41 --> 11:44and then in 2003 there was a larger sort
- 11:44 --> 11:47of more systematic update to Medicare that
- 11:47 --> 11:50generalized coverage for preventive services.
- 11:50 --> 11:51The next.
- 11:51 --> 11:51Iteration,
- 11:51 --> 11:55the big next big change came in
- 11:55 --> 11:562010 with the Affordable Care Act
- 11:56 --> 11:58and the Affordable Care Act made
- 11:58 --> 12:00important revisions or amendments.
- 12:00 --> 12:03The way that preventive services are covered,
- 12:03 --> 12:05the Affordable Care Act took the
- 12:05 --> 12:07step of linking insurance coverage
- 12:07 --> 12:10to evidence based recommendations.
- 12:10 --> 12:13They said that for private insurers,
- 12:13 --> 12:15those private insurers have
- 12:15 --> 12:16to cover preventive services,
- 12:16 --> 12:17including cancer screenings that
- 12:17 --> 12:21are given a top rating by the US
- 12:21 --> 12:22Preventive Services Task Force.
- 12:22 --> 12:23That's that committee.
- 12:23 --> 12:25That I mentioned that's composed of
- 12:25 --> 12:27doctors and public health experts
- 12:27 --> 12:29that evaluate the evidence in
- 12:29 --> 12:31the data around cancer screening
- 12:31 --> 12:32and other preventive services.
- 12:32 --> 12:34And if that group gives it its,
- 12:34 --> 12:35you know,
- 12:35 --> 12:37one of its strongest two ratings insurance
- 12:37 --> 12:39companies have to cover that service,
- 12:39 --> 12:40and they have to cover
- 12:40 --> 12:40it without cost sharing,
- 12:41 --> 12:42which means that they can't charge
- 12:42 --> 12:44an out of pocket component.
- 12:44 --> 12:48No deductible or copay or coinsurance,
- 12:48 --> 12:49so that was a step forward.
- 12:49 --> 12:50Now interestingly,
- 12:50 --> 12:52breast cancer screening for women
- 12:52 --> 12:55in their 40s is given AC rating.
- 12:55 --> 12:58By the US Preventive Services Task Force,
- 12:58 --> 13:00which means that there's some evidence
- 13:00 --> 13:03for small benefit, but it's not.
- 13:03 --> 13:05It's strongest A or B rating.
- 13:05 --> 13:07So under the Affordable Care Act.
- 13:09 --> 13:12Under the Affordable Care Act.
- 13:12 --> 13:14Insurance companies would
- 13:14 --> 13:16not be required to cover.
- 13:18 --> 13:19Breast cancer screening for
- 13:19 --> 13:21women in their 40s, however,
- 13:21 --> 13:22there was a separate statute
- 13:22 --> 13:24signed into law that requires
- 13:24 --> 13:26coverage for women in their 40s.
- 13:26 --> 13:27There's kind of a carve
- 13:27 --> 13:28out legislation that said,
- 13:28 --> 13:29we think it's important that
- 13:29 --> 13:30women in the 40s have access
- 13:30 --> 13:31to breast cancer screening,
- 13:31 --> 13:32so it's generally covered
- 13:32 --> 13:34by most private insurers.
- 13:34 --> 13:37I will say that the Affordable Care
- 13:37 --> 13:39Act doesn't apply to every insurer,
- 13:39 --> 13:40and it actually doesn't apply
- 13:40 --> 13:41to Medicare and Medicaid,
- 13:41 --> 13:43although those programs generally
- 13:43 --> 13:46cover breast cancer screening without
- 13:46 --> 13:48cost because of other legislation.
- 13:48 --> 13:49So it's always important to
- 13:49 --> 13:50check with your insurance,
- 13:50 --> 13:51'cause there's all kinds of
- 13:51 --> 13:52asterisks and exceptions,
- 13:52 --> 13:55but I think for most women with
- 13:55 --> 13:57private insurance with Medicare and
- 13:57 --> 13:58Medicaid breast cancer screening,
- 13:58 --> 13:59even for women in their 40s
- 13:59 --> 14:00is generally covered
- 14:01 --> 14:03We're going to pick up
- 14:03 --> 14:05this conversation right after we take
- 14:05 --> 14:07a short break for a medical minute.
- 14:07 --> 14:09Please stay tuned to learn more
- 14:09 --> 14:11about screening for breast and
- 14:11 --> 14:12lung cancers with my guest
- 14:12 --> 14:13Dr. Ilana Richman.
- 14:14 --> 14:16Funding for Yale Cancer Answers
- 14:16 --> 14:18comes from Smilow Cancer Hospital
- 14:18 --> 14:20where the breast cancer Prevention
- 14:20 --> 14:22Clinic provides comprehensive risk
- 14:22 --> 14:24assessment education and screening for
- 14:24 --> 14:26women at increased risk of breast cancer.
- 14:26 --> 14:30To learn more, visit Yale
- 14:30 --> 14:32Cancer Center org genetics.
- 14:32 --> 14:34Genetic testing can be useful for
- 14:34 --> 14:36people with certain types of cancer
- 14:36 --> 14:38that seem to run in their families.
- 14:38 --> 14:40Genetic counseling is a process that
- 14:40 --> 14:42includes collecting a detailed personal
- 14:42 --> 14:45and family history or risk assessment and
- 14:45 --> 14:48a discussion of genetic testing options.
- 14:48 --> 14:50Only about 5 to 10% of all
- 14:50 --> 14:51cancers are inherited,
- 14:51 --> 14:53and genetic testing is not
- 14:53 --> 14:54recommended for everyone.
- 14:54 --> 14:57Individuals who have a personal and
- 14:57 --> 14:59or family history that includes
- 14:59 --> 15:01cancer at unusually early ages.
- 15:01 --> 15:03Multiple relatives on the same side
- 15:03 --> 15:05of the family with the same cancer.
- 15:05 --> 15:08More than one diagnosis of cancer
- 15:08 --> 15:09in the same individual,
- 15:09 --> 15:12rare cancers or family history of a
- 15:12 --> 15:14known altered cancer predisposing gene
- 15:14 --> 15:17could be candidates for genetic testing.
- 15:17 --> 15:19Resources for genetic counseling and
- 15:19 --> 15:21testing are available at federally
- 15:21 --> 15:23designated comprehensive cancer
- 15:23 --> 15:25centers such as Yale Cancer Center
- 15:25 --> 15:27and Smilow Cancer Hospital.
- 15:27 --> 15:30More information is available at
- 15:30 --> 15:31yalecancercenter.org. You're listening
- 15:31 --> 15:33to Connecticut Public Radio.
- 15:34 --> 15:36Welcome back to Yale Cancer Answers.
- 15:36 --> 15:39This is doctor Anees Chagpar and I'm joined
- 15:39 --> 15:42tonight by my guest Doctor Ilana Richman.
- 15:42 --> 15:44We're learning about screening for
- 15:44 --> 15:46breast and lung cancers and Alana.
- 15:46 --> 15:49You left off right before the break
- 15:49 --> 15:52talking about the Affordable Care Act
- 15:52 --> 15:55and the fact that it mandated that
- 15:55 --> 15:58for people with private insurance,
- 15:58 --> 16:01those insurers have to cover
- 16:01 --> 16:04screening for cancer.
- 16:04 --> 16:10That has reached the level of evidence
- 16:10 --> 16:14based recommendations from the USPSTF.
- 16:14 --> 16:16But you also made one comment
- 16:16 --> 16:18which I wanted to go back to,
- 16:18 --> 16:22which was there's a lot of asterisks
- 16:22 --> 16:25and it's most private insurers tell
- 16:25 --> 16:26us a little bit more about that.
- 16:26 --> 16:29I mean, how do you know if you
- 16:29 --> 16:32are in the most private insurers,
- 16:32 --> 16:34or whether there's a carve out
- 16:34 --> 16:37which might leave you with a bill?
- 16:37 --> 16:40So the insurers that are covered
- 16:40 --> 16:42under the Affordable Care Act don't
- 16:42 --> 16:44include firms that are self insured,
- 16:44 --> 16:47so lots of large companies actually don't
- 16:47 --> 16:49pay for traditional health insurance.
- 16:49 --> 16:51What they do is set aside money to directly,
- 16:51 --> 16:53essentially directly pay for the
- 16:53 --> 16:55health care of their employees,
- 16:55 --> 16:57which is not considered traditional
- 16:57 --> 16:59insurance and not is not covered under
- 16:59 --> 17:01statutes like the Affordable Care Act.
- 17:01 --> 17:02On the other hand,
- 17:02 --> 17:04lots of those companies that do that
- 17:04 --> 17:07still conform to the general kinds of
- 17:07 --> 17:10coverage that other large insurers offer,
- 17:10 --> 17:12so that's why I say it's important to
- 17:12 --> 17:14check with your insurance company just
- 17:14 --> 17:16to make sure you won't be surprised.
- 17:16 --> 17:17Unpleasantly surprised if you
- 17:17 --> 17:19end up with a bill.
- 17:19 --> 17:21I don't think there's one other
- 17:21 --> 17:24asterisk to be aware of, which is that.
- 17:24 --> 17:26Not all kinds of breast cancer
- 17:26 --> 17:28screening are covered equally,
- 17:28 --> 17:30so for example.
- 17:30 --> 17:33Most insurance as we talked about
- 17:33 --> 17:35covers breast cancer screening,
- 17:35 --> 17:38but that's sort of narrowly interpreted
- 17:38 --> 17:41to mean traditional digital mammography.
- 17:41 --> 17:43Other newer technologies like
- 17:43 --> 17:443 dimensional mammography,
- 17:44 --> 17:47also known as digital breast tomosynthesis.
- 17:47 --> 17:50Or add on tests like ultrasound
- 17:50 --> 17:52or MRI may not be covered.
- 17:52 --> 17:55So if if those tests are recommended
- 17:55 --> 17:58or considered again it could be
- 17:58 --> 17:59important to ask whether they're
- 17:59 --> 18:01covered or whether you might be
- 18:01 --> 18:02responsible for share of the cost.
- 18:03 --> 18:05You know that's really interesting,
- 18:05 --> 18:07because I think that there are a lot
- 18:07 --> 18:09of women who go for their mammogram.
- 18:09 --> 18:12It just so happens that the place where I
- 18:12 --> 18:14get my mammogram only has tomosynthesis,
- 18:14 --> 18:18but what you're saying is that?
- 18:18 --> 18:21That might not be covered.
- 18:21 --> 18:23It depends on the state you live.
- 18:23 --> 18:25Some seats actually have
- 18:25 --> 18:27additional protections to ensure
- 18:27 --> 18:29that that service is covered.
- 18:29 --> 18:31Including the state of Connecticut,
- 18:31 --> 18:32but not all do.
- 18:32 --> 18:34So again, it's important to, I think,
- 18:34 --> 18:37ask what you might be responsible for,
- 18:37 --> 18:38and then even if you were to receive
- 18:38 --> 18:40one of those additional tests,
- 18:40 --> 18:41it might be that you're only
- 18:41 --> 18:42responsible for a portion of
- 18:42 --> 18:42it and not the whole thing.
- 18:42 --> 18:44But yes, you're right, women.
- 18:44 --> 18:46I think often don't always go into the test,
- 18:46 --> 18:47know exactly what they're going to get,
- 18:47 --> 18:49and it's pretty tough to be in the
- 18:49 --> 18:51moment and and concerned about.
- 18:51 --> 18:53You know whether or not you're going to
- 18:53 --> 18:55have a bill for what's what tests you get.
- 18:56 --> 18:59Is there any legal mandate for.
- 18:59 --> 19:03A you know a facility to tell you hey,
- 19:03 --> 19:07you know we are going to do a 3D mammogram,
- 19:07 --> 19:10and oh, by the way, that isn't
- 19:10 --> 19:12covered in this particular state.
- 19:13 --> 19:15I don't know that there's a
- 19:15 --> 19:17regulation of around disclosure.
- 19:17 --> 19:19Most facilities will have you agree
- 19:19 --> 19:22to pay if you're if there's a
- 19:22 --> 19:24component that you're liable for,
- 19:24 --> 19:25but I don't know if they're required
- 19:25 --> 19:27to disclose the cost upfront.
- 19:27 --> 19:30Yeah, that's really great information,
- 19:30 --> 19:32because it really does then
- 19:32 --> 19:35behoove people to ask you think?
- 19:35 --> 19:36I know that my insurance
- 19:36 --> 19:37coverage preventative care.
- 19:37 --> 19:39I know that they'll cover a mammogram,
- 19:39 --> 19:41but they may not cover it.
- 19:41 --> 19:44The mammogram that that particular?
- 19:44 --> 19:47A facility is offering in some states,
- 19:47 --> 19:49but it's good to know that
- 19:49 --> 19:51Connecticut does cover it.
- 19:51 --> 19:54The other thing that was interesting is
- 19:54 --> 19:57that it may not cover the accessory tests,
- 19:57 --> 19:59so you get a mammogram.
- 19:59 --> 20:01The mammogram sees something,
- 20:01 --> 20:04and your doctor says, well,
- 20:04 --> 20:06we need to look at that more
- 20:06 --> 20:07closely with an ultrasound,
- 20:07 --> 20:09or you've got dense breast tissue.
- 20:09 --> 20:12So we need to add on.
- 20:12 --> 20:13Ultrasound,
- 20:13 --> 20:16or maybe you've got a genetic
- 20:16 --> 20:19predisposition and your doctor says,
- 20:19 --> 20:19well,
- 20:19 --> 20:21you know you really need to
- 20:21 --> 20:23be screened with MRI,
- 20:23 --> 20:26but those tests may not be covered either.
- 20:27 --> 20:28That's right, or they may be covered in
- 20:28 --> 20:30part and you might have in it, you know,
- 20:30 --> 20:33copay or it might be part of your deductible,
- 20:33 --> 20:35at least under the Affordable Care Act.
- 20:35 --> 20:37None of those scenarios are
- 20:37 --> 20:38covered under the recommendations
- 20:38 --> 20:40that require coverage in full,
- 20:40 --> 20:42so those are outside of of what
- 20:42 --> 20:43the Affordable Care Act requires.
- 20:43 --> 20:45Now lots of insurance companies.
- 20:45 --> 20:46I would say OK,
- 20:46 --> 20:47those are medically necessary tests
- 20:47 --> 20:49and would cover them the way that they
- 20:49 --> 20:51would cover lots of other medical care.
- 20:51 --> 20:52But at least in terms of
- 20:52 --> 20:53the Affordable Care Act,
- 20:53 --> 20:56those are outside of the kind of narrow
- 20:56 --> 20:57recommendations around preventive
- 20:57 --> 20:58services and so are not required
- 20:58 --> 21:01to be covered under that statute.
- 21:01 --> 21:03The other thing is when we when
- 21:03 --> 21:05we're talking about lung cancer,
- 21:05 --> 21:08is well, can you kind of go over,
- 21:08 --> 21:12you know, the groups of people
- 21:12 --> 21:14who should get low dose CT scans.
- 21:14 --> 21:16I at the top of the show you
- 21:16 --> 21:18were kind of mentioning that.
- 21:18 --> 21:19For many years,
- 21:19 --> 21:21we really didn't have screening tests,
- 21:21 --> 21:26but now with low dose that is something that
- 21:26 --> 21:29is covered for for lung cancer screening,
- 21:29 --> 21:31but it's only covered
- 21:31 --> 21:32for certain populations.
- 21:32 --> 21:33Is that right?
- 21:33 --> 21:35Can you tell us who
- 21:35 --> 21:36benefits from a low dose CT
- 21:37 --> 21:40so low dose CT has been studied in high
- 21:40 --> 21:42risk populations and what's meant by
- 21:42 --> 21:45high risk is older adults who have a
- 21:45 --> 21:47substantial history of tobacco use.
- 21:47 --> 21:50Tobacco use is, of course the number one.
- 21:50 --> 21:53Risk factor for developing lung cancer.
- 21:53 --> 21:54Not all people who develop lung
- 21:54 --> 21:56cancer have a history of tobacco use,
- 21:56 --> 21:58but it is the strongest risk factor
- 21:58 --> 22:00serving the general population.
- 22:00 --> 22:03The most common risk factor we recommend
- 22:03 --> 22:05lung cancer screening for adults who are
- 22:05 --> 22:08between the ages of 50 and 80 who have
- 22:08 --> 22:11used tobacco within the past 15 years.
- 22:11 --> 22:14So either our current smokers or who
- 22:14 --> 22:16quit within the last 15 years and
- 22:16 --> 22:18who have a substantial tobacco use
- 22:18 --> 22:20history and by substantial I mean.
- 22:21 --> 22:23Have smoked at least a pack a day
- 22:23 --> 22:25or an equivalent for 20 years.
- 22:25 --> 22:27So that might mean so by equivalent.
- 22:27 --> 22:28An example would be if you smoked
- 22:28 --> 22:30half a pack a day for 40 years
- 22:30 --> 22:32or one pack a day for 20 years.
- 22:32 --> 22:35If you you know smoked a quarter
- 22:35 --> 22:38of a pack a day 40 years ago,
- 22:38 --> 22:41you would not have enough of a tobacco use
- 22:41 --> 22:43history to warrant lung cancer screening,
- 22:43 --> 22:45but for people who fit those criteria,
- 22:45 --> 22:47we think there's a substantial benefit
- 22:47 --> 22:50to being screened and people you know
- 22:50 --> 22:52would enter screening whenever there.
- 22:52 --> 22:54Identified as being eligible and the
- 22:54 --> 22:57idea is to continue to screen actually
- 22:57 --> 23:00annually every year with a chest CT
- 23:00 --> 23:03until one of several things happen,
- 23:03 --> 23:05either age out or it's been more
- 23:05 --> 23:07than 15 years since you quit smoking,
- 23:07 --> 23:09or you know you're diagnosed at
- 23:09 --> 23:10the lung cancer,
- 23:10 --> 23:11which hopefully would not happen.
- 23:11 --> 23:14But of course does from time to time,
- 23:14 --> 23:16so people who meet any of those criteria
- 23:16 --> 23:17could be considered for lung cancer.
- 23:17 --> 23:19Screening would continue annual screening
- 23:19 --> 23:21until one of those stopping points is met.
- 23:21 --> 23:23One of the questions that people might.
- 23:23 --> 23:26Be thinking about is how did they
- 23:26 --> 23:29come up with these guidelines?
- 23:29 --> 23:30Because you can understand that
- 23:30 --> 23:33you know the longer you smoke,
- 23:33 --> 23:34the higher your risk.
- 23:34 --> 23:37If you quit smoking many many years ago,
- 23:37 --> 23:42the lower your risk, the older you are.
- 23:42 --> 23:44Perhaps your increased risk,
- 23:44 --> 23:47but there's always some nuances so
- 23:47 --> 23:50you know people might be saying.
- 23:50 --> 23:53Well, an 80 year old who quit smoking
- 23:53 --> 23:5614 years ago and and smoked 20
- 23:56 --> 23:59pack years prior to that is covered
- 23:59 --> 24:02for a low dose CT even though
- 24:02 --> 24:05his life expectancy is fairly low
- 24:05 --> 24:07and his risk might be moderate,
- 24:07 --> 24:11whereas a 45 year old who might
- 24:11 --> 24:12have been smoking.
- 24:12 --> 24:16You know, since he was 10 or 15.
- 24:16 --> 24:20So say a 30 pack year history.
- 24:20 --> 24:23Is not covered because he's not old enough,
- 24:23 --> 24:25even though he's a current smoker.
- 24:25 --> 24:29So how do you kind of explain that to people?
- 24:29 --> 24:31The guidelines are really based
- 24:31 --> 24:33on two sets of information.
- 24:33 --> 24:35One is the clinical trials that
- 24:35 --> 24:37have been done, and then it's
- 24:37 --> 24:39probably our kind of gold standard.
- 24:39 --> 24:41Go to and they have really
- 24:41 --> 24:42been two clinical trials,
- 24:42 --> 24:44one done in the United States,
- 24:44 --> 24:45one in Europe.
- 24:45 --> 24:48They had slightly different entry
- 24:48 --> 24:51criteria and use slightly different
- 24:51 --> 24:53methods for detecting lung cancer,
- 24:53 --> 24:55but we try to match.
- 24:55 --> 24:58The population that we recommend lung
- 24:58 --> 25:01cancer screening for to those trials
- 25:01 --> 25:04because if we deviate you know much from
- 25:04 --> 25:06that then we really don't understand.
- 25:06 --> 25:08You know if we start recommending lung
- 25:08 --> 25:11cancer to people in their early 40s or 30s.
- 25:11 --> 25:12How you know how would those
- 25:12 --> 25:14populations have fared if we were
- 25:14 --> 25:15to actually study them in a trial?
- 25:15 --> 25:18They're sort of too far away from the data.
- 25:18 --> 25:21We have the 2nd way that recommendations
- 25:21 --> 25:24are made is through modeling,
- 25:24 --> 25:26and modeling is a approach
- 25:26 --> 25:29where we can actually simulate.
- 25:29 --> 25:30Using computer models,
- 25:30 --> 25:32the progression of cancer in kind
- 25:32 --> 25:34of a hypothetical or theoretical
- 25:34 --> 25:36population of patients and ask OK if
- 25:36 --> 25:38we screen people at these intervals
- 25:38 --> 25:39or these age ranges, what happens?
- 25:39 --> 25:41And so that's in part how some
- 25:41 --> 25:43of these decisions were made,
- 25:43 --> 25:44particularly around the upper
- 25:44 --> 25:46end of the age limit.
- 25:46 --> 25:48The child is didn't actually enroll people,
- 25:48 --> 25:50or at least the US trial didn't
- 25:50 --> 25:51actually enroll people in their 80s.
- 25:51 --> 25:54But modeling studies showed that.
- 25:54 --> 25:57Because lung cancer tends to be an
- 25:57 --> 25:59aggressive disease even among older
- 25:59 --> 26:01adults who naturally have a shorter
- 26:01 --> 26:02life expectancy due to their age,
- 26:02 --> 26:04there's still potential benefit even
- 26:04 --> 26:07you know, screen in the late 70s.
- 26:07 --> 26:09So that's how some of those
- 26:09 --> 26:11age ranges are established.
- 26:11 --> 26:14There's always some trade off,
- 26:14 --> 26:16so you could screen a broader and
- 26:16 --> 26:17broader population and derive
- 26:17 --> 26:18some incremental benefit from
- 26:18 --> 26:20expanding the screening criteria.
- 26:20 --> 26:22But as screening moves to lower
- 26:22 --> 26:23and lower risk populations,
- 26:23 --> 26:24you start to accrue,
- 26:24 --> 26:26you know on the population
- 26:26 --> 26:27level more harm than benefit.
- 26:27 --> 26:29So at some point we have to draw a
- 26:29 --> 26:30line and say this is the general
- 26:30 --> 26:32group that we think will benefit from
- 26:32 --> 26:34screening or the benefits outweigh the harms.
- 26:35 --> 26:39And so I think you know to to that point.
- 26:39 --> 26:42People kind of going full circle back to
- 26:42 --> 26:44where we we started the conversation.
- 26:44 --> 26:47People really need to think about the
- 26:47 --> 26:51fact that a these guidelines are based on
- 26:51 --> 26:54evidence of populations and we know that
- 26:54 --> 26:57in general provide more good than harm,
- 26:57 --> 27:00which is why they're recommended.
- 27:00 --> 27:01But that sometimes these things
- 27:01 --> 27:03need to be individualized.
- 27:03 --> 27:05There may be different guidelines based
- 27:05 --> 27:07on different societies and things that
- 27:07 --> 27:09you should talk to your doctor about.
- 27:09 --> 27:13But I want to end kind of where the
- 27:13 --> 27:15whole situation started when you were
- 27:15 --> 27:17talking about one of the reasons
- 27:17 --> 27:20you got into primary care was really
- 27:20 --> 27:21to keep people healthy,
- 27:21 --> 27:24and cancer screening is part of that.
- 27:25 --> 27:28What percentage of people actually
- 27:28 --> 27:31follow these guidelines and do you
- 27:31 --> 27:34have any advice for clinicians or
- 27:34 --> 27:37patients or family members in terms
- 27:37 --> 27:39of encouraging people to follow
- 27:39 --> 27:40these guidelines?
- 27:41 --> 27:43It's actually really desperate.
- 27:43 --> 27:45Depending on the screen
- 27:45 --> 27:46tests we're talking about.
- 27:46 --> 27:49So among women who are eligible
- 27:49 --> 27:50for breast cancer screening,
- 27:50 --> 27:52the United States, about 2/3 of
- 27:52 --> 27:54eligible women have been screened.
- 27:54 --> 27:55Which is quite high.
- 27:55 --> 27:56I mean it means that there are
- 27:56 --> 27:58some women who are eligible have
- 27:58 --> 28:00not been screened and there may be
- 28:00 --> 28:01good reasons for some of those,
- 28:01 --> 28:03and there may be not good reasons for others.
- 28:03 --> 28:05There may be still women who we ought to
- 28:05 --> 28:07be reaching and trying harder to reach.
- 28:07 --> 28:08But in general I think we've done a
- 28:08 --> 28:10pretty good job and I'd see it said
- 28:10 --> 28:12getting the word out about breast cancer
- 28:12 --> 28:14screening and bringing women into care.
- 28:14 --> 28:16Lung cancer screening is a bit of
- 28:16 --> 28:18a different scenario where only
- 28:18 --> 28:21about 10% of eligible folks have
- 28:21 --> 28:23been screened and part of it is
- 28:23 --> 28:24that I think again we need
- 28:24 --> 28:26to be better about messaging and
- 28:26 --> 28:27also about developing systems.
- 28:27 --> 28:30To make it easy for primary care doctors
- 28:30 --> 28:32to think of it and propose it to patients.
- 28:33 --> 28:35Doctor Ilana Richman is an assistant
- 28:35 --> 28:37professor in internal medicine
- 28:37 --> 28:39at the Yale School of Medicine.
- 28:39 --> 28:41If you have questions,
- 28:41 --> 28:43the address is canceranswers@yale.edu
- 28:43 --> 28:46and past editions of the program
- 28:46 --> 28:48are available in audio and written
- 28:48 --> 28:49form at yalecancercenter.org.
- 28:49 --> 28:51We hope you'll join us next week to
- 28:51 --> 28:53learn more about the fight against
- 28:53 --> 28:55cancer here on Connecticut Public
- 28:55 --> 28:57radio funding for Yale Cancer Answers
- 28:57 --> 29:00is provided by Smilow Cancer Hospital.
Information
Screening for Breast and Lung Cancers with guest Dr. Ilana Richman
February 13, 2022
Yale Cancer Center
visit: http://www.yalecancercenter.org
email: canceranswers@yale.edu
call: 203-785-4095
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Dr. Ilana RichmanTo Cite
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