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Robert Bazell

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  • 00:08 --> 00:11Hello and welcome to Science et al podcast,
  • 00:11 --> 00:12but everything science sponsored
  • 00:12 --> 00:14by the Yale School of Medicine.
  • 00:14 --> 00:16I'm your host, Daniel Barron.
  • 00:16 --> 00:18And in this episode I'm
  • 00:18 --> 00:20speaking with Robert Bazell.
  • 00:20 --> 00:23Robert or Bob as he asked me to call him,
  • 00:23 --> 00:25worked his NBC's chief science
  • 00:25 --> 00:26correspondent for 38 years.
  • 00:26 --> 00:28In that capacity, Bob and many awards,
  • 00:28 --> 00:30including five Emmy Awards,
  • 00:30 --> 00:32the Peabody Award, and the DuPont Award.
  • 00:32 --> 00:34He also authored a bestselling
  • 00:34 --> 00:35book called her two,
  • 00:35 --> 00:37The Making of a revolutionary
  • 00:37 --> 00:38treatment for breast Cancer,
  • 00:38 --> 00:41which was adapted as a TV film.
  • 00:41 --> 00:44Now Bob is supposedly formally retired,
  • 00:44 --> 00:46even though he's quite busy at
  • 00:46 --> 00:47yells Department of Molecular
  • 00:47 --> 00:49Cellular and Developmental Biology,
  • 00:49 --> 00:52where he spends his time mentoring
  • 00:52 --> 00:53aspiring journalist scientists.
  • 00:53 --> 00:56An anyone who wants to communicate
  • 00:56 --> 00:57more effectively with the public,
  • 00:57 --> 00:58including myself.
  • 00:58 --> 01:00I ran into Bob's Science
  • 01:00 --> 01:02journalism panel at Yale,
  • 01:02 --> 01:05where he was one of the primary panelists.
  • 01:05 --> 01:07I had never met him in person
  • 01:07 --> 01:08and didn't recognize him,
  • 01:08 --> 01:11but instantly recognized his voice.
  • 01:11 --> 01:12And after the panel discussion,
  • 01:12 --> 01:14I Googled Bob and reviewed
  • 01:14 --> 01:16some of his videos,
  • 01:16 --> 01:18some of which I still
  • 01:18 --> 01:19remembered from decades before.
  • 01:19 --> 01:21It was kind of strange to see him
  • 01:21 --> 01:24with Bill Clinton and a lot of
  • 01:24 --> 01:26the AIDS and cancer treatments
  • 01:26 --> 01:28and the Human Genome Project.
  • 01:28 --> 01:30It was really, it was really.
  • 01:30 --> 01:32It was really fascinating.
  • 01:32 --> 01:33Bob's had an enormous impact,
  • 01:33 --> 01:36only that I and I suppose many of
  • 01:36 --> 01:39listeners think about and appreciate science.
  • 01:39 --> 01:42It was a real honor to speak with Bob
  • 01:42 --> 01:45about his work and to see from his eyes at,
  • 01:45 --> 01:46you know,
  • 01:46 --> 01:48the 10,000 foot view how he views
  • 01:48 --> 01:50science and how science meshes
  • 01:50 --> 01:51with politics and public policy,
  • 01:51 --> 01:53social movements and with the
  • 01:53 --> 01:55scientific community itself.
  • 01:55 --> 01:56So here we go.
  • 01:56 --> 01:57Thanks again to
  • 02:06 --> 02:09Well, thank you for coming and for
  • 02:09 --> 02:12letting me pick your brain yet again.
  • 02:12 --> 02:14It was really interesting so I
  • 02:14 --> 02:17had not really met you formally,
  • 02:17 --> 02:19but I first I could say heard your
  • 02:19 --> 02:22voice from the back of a lecture
  • 02:22 --> 02:24Hall during a panel discussion with
  • 02:24 --> 02:27Carl Zimmer Anneliese Sanders,
  • 02:27 --> 02:29an I recognized your voice.
  • 02:29 --> 02:30Really quite quickly actually.
  • 02:30 --> 02:33So I was like, oh, wow,
  • 02:33 --> 02:36I know this guy and so after that I just
  • 02:36 --> 02:40I did what I think by your definition
  • 02:40 --> 02:43would be a not quite a deep dive but.
  • 02:43 --> 02:45Dipping my toe in the finger
  • 02:45 --> 02:48of your huge body of work.
  • 02:48 --> 02:50And obviously you've reported on
  • 02:50 --> 02:53far more than 4000 stories and I
  • 02:53 --> 02:56was able to go on to NBC's website
  • 02:56 --> 02:58and watch some of the videos that
  • 02:58 --> 03:01you had made like some of the
  • 03:01 --> 03:03reporting you did for the TV.
  • 03:03 --> 03:04By
  • 03:04 --> 03:07the way, if you want to see videos
  • 03:07 --> 03:10from history, you can open the
  • 03:10 --> 03:12Yale Library and Vanderbilt.
  • 03:12 --> 03:14Library has an archive of every television
  • 03:14 --> 03:17show that's been produced since 1968,
  • 03:17 --> 03:20and you go live stream it. I had no idea,
  • 03:20 --> 03:22so you can watch just everything.
  • 03:22 --> 03:23You can watch everything.
  • 03:23 --> 03:25Well, let's pick a moment in
  • 03:25 --> 03:27history that's kind of scary.
  • 03:27 --> 03:28Actually, there's
  • 03:28 --> 03:30a lot of junk on television. There's a
  • 03:30 --> 03:33lot of junk, but it also is for me.
  • 03:33 --> 03:35It's been a very useful
  • 03:35 --> 03:36tool for undergraduates,
  • 03:36 --> 03:38because if I'm teaching a course on,
  • 03:38 --> 03:40say, the history of HIV AIDS,
  • 03:40 --> 03:42which I'm doing now, or.
  • 03:42 --> 03:45Events in public health that I take it back,
  • 03:45 --> 03:48take them back and show them these.
  • 03:48 --> 03:50Videos 'cause I wouldn't have access to them.
  • 03:50 --> 03:53NBC owns them, but I can show it,
  • 03:53 --> 03:56show it to them and they are absolutely
  • 03:56 --> 03:58fascinated to hear the inside story of.
  • 03:58 --> 04:00How this happened and then to see
  • 04:00 --> 04:02the people that they're not just
  • 04:02 --> 04:04reading about it in an article or
  • 04:04 --> 04:06at a Journal article or a popular
  • 04:06 --> 04:08article, many of whom you interviewed?
  • 04:08 --> 04:10Yeah, why didn't they see me interviewing
  • 04:10 --> 04:12them and then I can tell them
  • 04:12 --> 04:13what they're really like.
  • 04:13 --> 04:15This person was a decent person.
  • 04:15 --> 04:17This one is not one of the videos,
  • 04:17 --> 04:20so there are 480 videos on the NBC website,
  • 04:20 --> 04:22so this is 10 to what I did.
  • 04:22 --> 04:24Sure right, but you know,
  • 04:24 --> 04:26it's still a lot for me and
  • 04:26 --> 04:28there's one video in particular.
  • 04:28 --> 04:29It was from 1981.
  • 04:29 --> 04:31Where you had this excellent white linen
  • 04:31 --> 04:34sports coat and purple tie purple shirt,
  • 04:34 --> 04:36your hairs gotta fro delivery.
  • 04:36 --> 04:39Bring all that up.
  • 04:39 --> 04:41Great, so great and you're interviewing
  • 04:41 --> 04:43BF Skinner about some experiments
  • 04:43 --> 04:45that he's doing with pigeons.
  • 04:45 --> 04:46You know unpacking and, well,
  • 04:46 --> 04:49you know the different files and stuff.
  • 04:49 --> 04:53I had a great honor and for a long time on
  • 04:53 --> 04:57the Today Show in the 80s where I they won't,
  • 04:57 --> 04:59they took a science segment which is
  • 04:59 --> 05:02very rare an I was allowed to pick and
  • 05:02 --> 05:05anything I wanted to and I found out
  • 05:05 --> 05:08that Skinner was still around, which was
  • 05:08 --> 05:10surprising because it was so famous.
  • 05:10 --> 05:13And he was a great interview.
  • 05:13 --> 05:15It was a very wry sense of
  • 05:15 --> 05:17humor and the funny character.
  • 05:17 --> 05:20And he had this idea of everything.
  • 05:20 --> 05:21Everything as I recently started
  • 05:21 --> 05:23wearing hearing aids myself.
  • 05:23 --> 05:24But in those days,
  • 05:24 --> 05:26hearing aids were quite visible and he,
  • 05:26 --> 05:28being the behaviorist that he was,
  • 05:28 --> 05:31he told me that the effect of
  • 05:31 --> 05:33hearing aid seems to be it made
  • 05:33 --> 05:35people scream at him 'cause
  • 05:35 --> 05:37they would see it here.
  • 05:39 --> 05:39Operant conditioning.
  • 05:39 --> 05:41He didn't think the hearing aids
  • 05:41 --> 05:43were enhancing his hearing,
  • 05:43 --> 05:45but he may make people screw you.
  • 05:45 --> 05:47Wow that would have been
  • 05:47 --> 05:48such a wonderful experience.
  • 05:48 --> 05:49I've obviously never met Skinner,
  • 05:49 --> 05:52but I've read a lot of his
  • 05:52 --> 05:53work and seeing how it
  • 05:53 --> 05:55influences and he had some
  • 05:55 --> 05:57students that I followed up with
  • 05:57 --> 05:59who made enormous fan of all.
  • 05:59 --> 06:01Of other people, for instance,
  • 06:01 --> 06:03people were trying to teach
  • 06:03 --> 06:04a language to chimpanzees,
  • 06:04 --> 06:06and they proved that they could
  • 06:06 --> 06:08get pigeons to do exactly what
  • 06:08 --> 06:10these people are getting the
  • 06:10 --> 06:11chimpanzees to do.
  • 06:11 --> 06:12Pressing the buttons,
  • 06:12 --> 06:13community communicating
  • 06:13 --> 06:14right exactly spelling out
  • 06:14 --> 06:16words which really weren't really doing
  • 06:16 --> 06:19well. There was such as a light going
  • 06:19 --> 06:22through a lot of your work and I wanted
  • 06:22 --> 06:24to kind of start farther back because
  • 06:24 --> 06:27I find it absolutely fascinating.
  • 06:27 --> 06:28So you did your undergraduate
  • 06:28 --> 06:29work and Berkeley.
  • 06:29 --> 06:35Seemingly at a time when there was like huge.
  • 06:35 --> 06:36Protest political unrest.
  • 06:36 --> 06:39You know the 60 seven was it when
  • 06:39 --> 06:41you graduated, graduated in 67.
  • 06:41 --> 06:44I started in the fall of 60 three and
  • 06:44 --> 06:47the free Speech movement was in 64 and
  • 06:47 --> 06:50Berkeley was way ahead of the rest of the
  • 06:50 --> 06:52country in terms of being disruptive.
  • 06:52 --> 06:55And I had my eye on my own back.
  • 06:55 --> 06:58Story to that is that I had dropped
  • 06:58 --> 07:00out of high school an I worked
  • 07:00 --> 07:03as a merchant Seaman for awhile.
  • 07:03 --> 07:05I'm traveling around the Pacific
  • 07:05 --> 07:08so I got that. I got to Berkeley.
  • 07:08 --> 07:10I got the equivalent of GD and
  • 07:10 --> 07:11I went to Berkeley
  • 07:11 --> 07:13and I'm sorry can we step back?
  • 07:13 --> 07:15Can you help me understand
  • 07:15 --> 07:17what a merchant Seaman is?
  • 07:17 --> 07:19Oh I have this vision of EB
  • 07:19 --> 07:20White working on a cruise
  • 07:20 --> 07:22vessel going up to Alaska or
  • 07:22 --> 07:24something was not that different.
  • 07:24 --> 07:26I was in a cooks and stewards union
  • 07:26 --> 07:28so that I wash dishes at sometimes
  • 07:28 --> 07:31if I got a good job you would
  • 07:31 --> 07:33bid on jobs at the Union Hall.
  • 07:33 --> 07:36If I got a good job I would
  • 07:36 --> 07:39be able to wait on tables or.
  • 07:39 --> 07:42Sometimes I had to clean up rooms,
  • 07:42 --> 07:44it was it was interesting mixture
  • 07:44 --> 07:46of things and sometimes it worked
  • 07:46 --> 07:48on freighters which were much
  • 07:48 --> 07:50more less contact with the public.
  • 07:50 --> 07:52But this was long enough ago that
  • 07:52 --> 07:54there were American passenger ships,
  • 07:54 --> 07:56so people were traveling to Hawaii
  • 07:56 --> 07:59and Australia and Tahiti on ships was
  • 07:59 --> 08:03quite an experience, so I was a bit.
  • 08:03 --> 08:07In front of my classmates when I got there.
  • 08:07 --> 08:09In terms of life experience and
  • 08:09 --> 08:12so that made me right away.
  • 08:12 --> 08:14Wine, wonder why these people are
  • 08:14 --> 08:16wasting their time protesting?
  • 08:16 --> 08:18Not that I disagree with the politics,
  • 08:18 --> 08:20but in retrospect a lot of them
  • 08:20 --> 08:22are very brave people who had gone
  • 08:22 --> 08:24to the Mississippi freedom Summers
  • 08:24 --> 08:27and put their lives on the line.
  • 08:27 --> 08:29And but when they came back they wanted
  • 08:29 --> 08:31to pick a fight with the University,
  • 08:31 --> 08:32and in retrospect,
  • 08:32 --> 08:36a lot of it was kind of silly at the
  • 08:36 --> 08:38time was whether you put a table
  • 08:38 --> 08:40here or 30 feet away from there
  • 08:40 --> 08:42an to give out pamphlets so.
  • 08:42 --> 08:45I had trouble at first getting used to it,
  • 08:45 --> 08:48and I think that the politics of Berkeley.
  • 08:48 --> 08:51Played a lot in my ending up
  • 08:51 --> 08:53being a journalist because.
  • 08:53 --> 08:56It was always very disruptive Ann.
  • 08:56 --> 08:59It was hard to concentrate, I didn't.
  • 08:59 --> 09:03I had was on track to be a scientist,
  • 09:03 --> 09:06I an I went away for a year and worked
  • 09:06 --> 09:09at the University of Sussex and then came
  • 09:09 --> 09:12back which allowed me to stay in Berkeley.
  • 09:12 --> 09:14Usually you have to do your
  • 09:14 --> 09:16graduate work someplace else,
  • 09:16 --> 09:18but keeping on the track to
  • 09:18 --> 09:20do what I had to do,
  • 09:20 --> 09:22I went to work in the laboratory
  • 09:22 --> 09:24of a Nobel Prize winner and this
  • 09:24 --> 09:27he was Melvin Calvin who discovered
  • 09:27 --> 09:28the photosynthesis cycle which
  • 09:28 --> 09:31is now known as the Calvin Cycle.
  • 09:31 --> 09:34But of course it wasn't in those days.
  • 09:34 --> 09:34Anne.
  • 09:34 --> 09:38He had a huge labion 20 combination
  • 09:38 --> 09:40of graduate students and postdocs.
  • 09:40 --> 09:41Ann,
  • 09:41 --> 09:44we decided in because that was the
  • 09:44 --> 09:47way we did things in those days too.
  • 09:47 --> 09:50Demand that he get off the Board of
  • 09:50 --> 09:52Directors of Dow Chemical because
  • 09:52 --> 09:53it made napalm.
  • 09:53 --> 09:55An he said to us,
  • 09:55 --> 09:59do go to hell just you're fired, he fired.
  • 09:59 --> 10:01All of us just called his name
  • 10:01 --> 10:03is student newspapers called the
  • 10:03 --> 10:04Saturday Night Massacre.
  • 10:04 --> 10:06So this is when you are Berkeley
  • 10:06 --> 10:07hours Berkeley. So I was right.
  • 10:07 --> 10:09This is what I was pushed.
  • 10:09 --> 10:10Fast forwarding to undergraduate student.
  • 10:10 --> 10:13K and I had finished by.
  • 10:13 --> 10:15Or else for my PhD and I was about
  • 10:15 --> 10:18to thinking about it thesis and at
  • 10:18 --> 10:20that moment I happened just fortuitously
  • 10:20 --> 10:23to meet somebody from Science magazine,
  • 10:23 --> 10:25and that's how I got into journalism.
  • 10:25 --> 10:27But if it hadn't met,
  • 10:27 --> 10:28Melvin Calvin hadn't kicked me
  • 10:28 --> 10:29out of his laboratory.
  • 10:29 --> 10:32I might have been assigned to this day.
  • 10:32 --> 10:34Oh wow, so that's that's
  • 10:34 --> 10:34absolutely fascinating.
  • 10:34 --> 10:36So so during your undergraduate years,
  • 10:36 --> 10:39you were you were writing, and I didn't
  • 10:39 --> 10:41write so much under my eyes.
  • 10:41 --> 10:42In my undergraduate years,
  • 10:42 --> 10:45I started that more as when I
  • 10:45 --> 10:47came back as a graduate student.
  • 10:47 --> 10:49And wrote a column for the
  • 10:49 --> 10:51Daily Californian's newspaper,
  • 10:51 --> 10:53but then they would buy.
  • 10:53 --> 10:56This is now in 1970 and.
  • 10:56 --> 10:58Long before can skate and
  • 10:58 --> 11:00a lot of other things,
  • 11:00 --> 11:01there was actually shootings
  • 11:01 --> 11:02in tear gas constantly.
  • 11:02 --> 11:03At Berkeley.
  • 11:03 --> 11:04It was a very,
  • 11:04 --> 11:05very disruptive from from
  • 11:05 --> 11:072 control of the protests.
  • 11:07 --> 11:09Or, yeah, yeah, absolutely yeah.
  • 11:09 --> 11:10This is a part of history
  • 11:10 --> 11:12that I don't know very well,
  • 11:12 --> 11:14so this is absolutely fascinating for
  • 11:14 --> 11:17me. Yeah, I wanted we could go off on that,
  • 11:17 --> 11:19but it's yeah, it was.
  • 11:19 --> 11:21There were so good science and good
  • 11:21 --> 11:23teaching and smart people there.
  • 11:23 --> 11:25Obviously it's a world class
  • 11:25 --> 11:27University and but I think that.
  • 11:27 --> 11:29In retrospect, the politics were
  • 11:29 --> 11:32so dominant that I got less out
  • 11:32 --> 11:34of the experience of being there
  • 11:34 --> 11:36that I could have if it were,
  • 11:36 --> 11:37say, yeah, or
  • 11:37 --> 11:40someplace else. What was it like
  • 11:40 --> 11:42working at a scientific lab?
  • 11:42 --> 11:43You know, a science lab.
  • 11:43 --> 11:46During a moment when there was a
  • 11:46 --> 11:48heavy anti science sentiment in
  • 11:48 --> 11:50your generation. I don't remember that my
  • 11:50 --> 11:53generation had anti science sentiment.
  • 11:53 --> 11:54The environmental movement was
  • 11:54 --> 11:57just beginning and I I had never.
  • 11:57 --> 12:00Seen as anti science and you talk
  • 12:00 --> 12:03about anti science now in terms of the
  • 12:03 --> 12:05regulations that the Trump administration
  • 12:05 --> 12:08is trying to illuminate. But I don't.
  • 12:08 --> 12:12I don't ever recall feeling and I any
  • 12:12 --> 12:15anti science sentiment and I don't.
  • 12:15 --> 12:17And Pew surveys now and things
  • 12:17 --> 12:19got along for a long time.
  • 12:19 --> 12:22In science, it held it enormous respect.
  • 12:22 --> 12:23Still an
  • 12:23 --> 12:25was then I guess I associate the
  • 12:25 --> 12:27protests against the war and
  • 12:27 --> 12:29against experimentation. Things like
  • 12:29 --> 12:30that. Yeah, well,
  • 12:30 --> 12:33the report is against the war for sure,
  • 12:33 --> 12:35and I felt very strongly and myself,
  • 12:35 --> 12:38and that it was an awful situation.
  • 12:38 --> 12:40But it wasn't about science except in
  • 12:40 --> 12:43very specific ways like making weapons.
  • 12:43 --> 12:44But the scientific community
  • 12:44 --> 12:45was growing enormously.
  • 12:45 --> 12:49In those days and one of the first stories
  • 12:49 --> 12:52I covered when I got to Science magazine
  • 12:52 --> 12:56was the war on cancer that Richard Nixon was.
  • 12:56 --> 12:57Forced to sign. He wasn't.
  • 12:57 --> 13:00Nobody put a gun to his head,
  • 13:00 --> 13:02but he was politically
  • 13:02 --> 13:04very wealthy lobbyists.
  • 13:04 --> 13:07Who spend all our time on health matters,
  • 13:07 --> 13:08name Mary Lasker.
  • 13:08 --> 13:10Put together this coalition of Democrats
  • 13:10 --> 13:13and Republicans and and they didn't want
  • 13:13 --> 13:15to hear about basic science they wanted.
  • 13:15 --> 13:18Why isn't there a cure for cancer and used
  • 13:18 --> 13:22and became known as the War on cancer even
  • 13:22 --> 13:25though it wasn't officially called that?
  • 13:25 --> 13:27But of course whenever you declare war
  • 13:27 --> 13:29on something that people start asking.
  • 13:29 --> 13:32Or are we winning the war?
  • 13:32 --> 13:34And that question goes on today?
  • 13:34 --> 13:35Because the.
  • 13:35 --> 13:36Numbers of.
  • 13:36 --> 13:39Cancer deaths in the United
  • 13:39 --> 13:42States especially are.
  • 13:42 --> 13:44Despite all the miraculous sounding
  • 13:44 --> 13:46things we hear about immunotherapy's
  • 13:46 --> 13:48another and targeted therapies,
  • 13:48 --> 13:50other treatments is vastly driven
  • 13:50 --> 13:53by the amount of people smoke or
  • 13:53 --> 13:56how many people are obese and
  • 13:56 --> 13:58things environmental factors that
  • 13:58 --> 14:01have nothing to do with treatment.
  • 14:02 --> 14:06So. The decision for you did go
  • 14:06 --> 14:08to Science magazine and become a
  • 14:08 --> 14:10full time writer. Yeah, I was. I
  • 14:10 --> 14:13was on the staff was very early announced.
  • 14:13 --> 14:16Now it's a giant and very.
  • 14:16 --> 14:17Very very good section
  • 14:17 --> 14:19of of Science magazine.
  • 14:19 --> 14:21But in those days just a few of us,
  • 14:21 --> 14:23I think I was a third
  • 14:23 --> 14:26higher reported on some of the biggest
  • 14:26 --> 14:28science stories that have happened in
  • 14:28 --> 14:30the last for more than my lifetime.
  • 14:30 --> 14:32At least the last 30 four
  • 14:32 --> 14:33years already I was.
  • 14:33 --> 14:36I was at NBC for 38 years
  • 14:36 --> 14:38an the I came there in nine.
  • 14:38 --> 14:42I went to local news for six months in.
  • 14:42 --> 14:451976, and then they sent me
  • 14:45 --> 14:47to Washington for a year.
  • 14:47 --> 14:49But I was always tagged to be the
  • 14:49 --> 14:51science and medicine correspondent.
  • 14:51 --> 14:53Was that on account of
  • 14:53 --> 14:55your science, training or
  • 14:55 --> 14:57person? Because of my size training,
  • 14:57 --> 14:59they in the mid 70s there were
  • 14:59 --> 15:00still only three networks,
  • 15:00 --> 15:03which of course makes an enormous difference.
  • 15:03 --> 15:05If you want to talk about televisions,
  • 15:05 --> 15:08nothing like the media environment of today.
  • 15:08 --> 15:10An enormous percentage of American
  • 15:10 --> 15:12public sat down at 6:30 or 7:00
  • 15:12 --> 15:14o'clock and watch the Evening
  • 15:14 --> 15:16News on one of the three networks.
  • 15:16 --> 15:19And that's why my voice was familiar to you.
  • 15:19 --> 15:20Because you.
  • 15:20 --> 15:23You heard it when you were growing up,
  • 15:23 --> 15:24along with almost everybody was
  • 15:24 --> 15:26on television and I remember a
  • 15:26 --> 15:28colleague when I got the NBC
  • 15:28 --> 15:29very beginning in my career.
  • 15:29 --> 15:31He said you have to realize there
  • 15:31 --> 15:34were fewer of us and he meant network
  • 15:34 --> 15:35television correspondents for the
  • 15:35 --> 15:37major news organizations here.
  • 15:37 --> 15:38There's fewer of us than there
  • 15:38 --> 15:40are members of the US Senate.
  • 15:41 --> 15:44I never thought of that. Yeah, that's
  • 15:44 --> 15:46fair, yeah, and he was so
  • 15:46 --> 15:48we had a position and uh,
  • 15:48 --> 15:50of authority and responsibility and I
  • 15:50 --> 15:52hope we carried out the responsibility,
  • 15:52 --> 15:54but it was nothing. And, you know,
  • 15:54 --> 15:56get recognized on the street.
  • 15:56 --> 15:58Then you know people like you reckon.
  • 15:58 --> 16:00Remember, my voice is for
  • 16:00 --> 16:01very heartening experience,
  • 16:01 --> 16:03so I had a touch of celebrity
  • 16:03 --> 16:05without any of the burdens of it.
  • 16:05 --> 16:06I was never.
  • 16:06 --> 16:09That's pretty ideal I guess. Yeah, right,
  • 16:09 --> 16:10because it was. It's
  • 16:10 --> 16:11interesting. Because the.
  • 16:14 --> 16:16I almost never had anybody complained
  • 16:16 --> 16:18to me about stories when they recognize
  • 16:18 --> 16:20me and I would get recognized a lot.
  • 16:20 --> 16:22And usually people wouldn't bother
  • 16:22 --> 16:24me with them when they did,
  • 16:24 --> 16:25it was just complementary.
  • 16:25 --> 16:27They say they enjoyed this story
  • 16:27 --> 16:29about this or that I remember.
  • 16:29 --> 16:30Speaking to Michael Kinsley,
  • 16:30 --> 16:32who was an editor at the
  • 16:32 --> 16:33time at the New Republic,
  • 16:33 --> 16:35where I occasionally wrote articles,
  • 16:35 --> 16:37and he was on Crossfire with Pat Buchanan,
  • 16:37 --> 16:40and he said, everybody came up to him,
  • 16:40 --> 16:42and they wanted to finish the argument.
  • 16:42 --> 16:43So if you're on,
  • 16:43 --> 16:45and that would be just the beginning
  • 16:45 --> 16:47of that kind of television where
  • 16:47 --> 16:48people scream at each other,
  • 16:48 --> 16:50we didn't do that, we told,
  • 16:50 --> 16:51told a story,
  • 16:51 --> 16:53and a certain amount of time.
  • 16:53 --> 16:53So it
  • 16:53 --> 16:55occur to me that you know,
  • 16:55 --> 16:57and I'm sure this is delivered on
  • 16:57 --> 17:00account of your the medium, that you're.
  • 17:00 --> 17:03Reporting on, but your story is.
  • 17:03 --> 17:04Almost invariably presented a
  • 17:04 --> 17:06scientific topic like some science
  • 17:06 --> 17:08concept very clearly very simply,
  • 17:08 --> 17:11but they also had a almost a case study,
  • 17:11 --> 17:12like a person involved,
  • 17:12 --> 17:14and so it's like you're
  • 17:14 --> 17:16presenting the concept and then
  • 17:16 --> 17:18the application of the concept.
  • 17:18 --> 17:19In the real world,
  • 17:19 --> 17:21an was at a common formula.
  • 17:21 --> 17:24Yeah, it was a very standard form,
  • 17:24 --> 17:24formulaic thing,
  • 17:24 --> 17:26and sometimes occasion there
  • 17:26 --> 17:28would be the occasional scandal.
  • 17:28 --> 17:30Or is the thing that things that
  • 17:30 --> 17:32didn't workout as as you plan,
  • 17:32 --> 17:35but for the most part.
  • 17:35 --> 17:36If you're telling a story
  • 17:36 --> 17:37about a medical advance,
  • 17:37 --> 17:40you have to have a human being in it,
  • 17:40 --> 17:42and I think that sometimes you
  • 17:42 --> 17:43can convey the wrong impression
  • 17:43 --> 17:46because you want to have the more
  • 17:46 --> 17:47attractive human being in it.
  • 17:47 --> 17:48And like, for instance,
  • 17:48 --> 17:50if you're doing a story about cancer
  • 17:50 --> 17:52that that was one of the questions
  • 17:52 --> 17:55I always ask my students is what's
  • 17:55 --> 17:56the biggest risk factor for cancer.
  • 17:56 --> 17:57And of course,
  • 17:57 --> 17:59people say chemicals or cigarettes
  • 17:59 --> 18:00is the most common answer,
  • 18:00 --> 18:03but of course it's age.
  • 18:03 --> 18:04Only one
  • 18:04 --> 18:06one out of eight women will
  • 18:06 --> 18:08develop breast cancer. Yeah,
  • 18:08 --> 18:10but most of them will develop in
  • 18:10 --> 18:12their 60s and 70s and then add
  • 18:12 --> 18:14it as since that's my cohort,
  • 18:15 --> 18:18I'm not eager for it to happen, but I'm just.
  • 18:18 --> 18:20But there are about 12,000 cases of
  • 18:20 --> 18:22pediatric cancer in the United States.
  • 18:22 --> 18:24Deaths from pediatric cancer in
  • 18:24 --> 18:26the United States every year,
  • 18:26 --> 18:28which each one is a horrible tragedy.
  • 18:28 --> 18:31But there's 600,000 deaths from adult cancer,
  • 18:31 --> 18:34so you have to look at that.
  • 18:34 --> 18:35As a proportion of
  • 18:35 --> 18:38the so you you knew you know the
  • 18:38 --> 18:41fundamentals of the field and immunology,
  • 18:41 --> 18:44and then you found yourself in the 80s
  • 18:44 --> 18:47and 90s reporting on the AIDS crisis.
  • 18:47 --> 18:50So how what was that like and how did
  • 18:50 --> 18:54you interact with the communities on the
  • 18:54 --> 18:57cyantific and the policy and the well?
  • 18:57 --> 19:01I was one of the first people there and
  • 19:01 --> 19:03that was so is very
  • 19:03 --> 19:05welcomed because they were.
  • 19:05 --> 19:07Languishing in lack of adversity
  • 19:07 --> 19:10and the lack of publicity was
  • 19:10 --> 19:12at the beginning was not just
  • 19:12 --> 19:14because of the Ronald Reagan,
  • 19:14 --> 19:16famously not saying the
  • 19:16 --> 19:17word aids for many years,
  • 19:17 --> 19:19and the government not being
  • 19:19 --> 19:21interested in disease.
  • 19:21 --> 19:23It very quickly was seem to
  • 19:23 --> 19:24be just affecting stigmatized
  • 19:24 --> 19:26groups and then poor countries,
  • 19:26 --> 19:28mostly in Sub Saharan Africa.
  • 19:28 --> 19:31But throughout the world there was
  • 19:31 --> 19:34also a lot of resistance in the gay
  • 19:34 --> 19:36community to talking about it at
  • 19:36 --> 19:39first because they didn't want it.
  • 19:39 --> 19:42They thought it would bring on more stigma,
  • 19:42 --> 19:45but it only been since the stone
  • 19:45 --> 19:49Stonewall riots in 1969 that there had
  • 19:49 --> 19:52been a gay liberation movement an in.
  • 19:52 --> 19:5319 was very recently I have
  • 19:53 --> 19:55to look this up with Lawrence
  • 19:55 --> 19:57versus Texas was in the 1980s,
  • 19:57 --> 20:00which is a Supreme Court case that said that.
  • 20:00 --> 20:01Anti sodomy laws were unconstitutional.
  • 20:01 --> 20:02I think was
  • 20:02 --> 20:04more recent than that. Yeah is
  • 20:04 --> 20:05very very recent.
  • 20:05 --> 20:09Yeah so a lot of you know a lot of
  • 20:09 --> 20:11states homosexuality was illegal right?
  • 20:11 --> 20:13And so they didn't want people
  • 20:13 --> 20:15coming in and asking them about it.
  • 20:15 --> 20:17So it was. It was, uh,
  • 20:17 --> 20:20I mean I quickly made friends
  • 20:20 --> 20:22and Anne was able to.
  • 20:22 --> 20:25Do and I mean my my greatest regret
  • 20:25 --> 20:27is I didn't do more about HIV aids
  • 20:27 --> 20:30even though I got a lot of credit
  • 20:30 --> 20:32for what I did do because I also
  • 20:32 --> 20:33at the same time was covering the
  • 20:33 --> 20:35space Shuttle artificial hearts.
  • 20:37 --> 20:39Rollins of Cancer and you know there was
  • 20:39 --> 20:41there was constantly constant stories
  • 20:41 --> 20:43and you just mentioned BF Skinner,
  • 20:43 --> 20:44which I'd completely forgotten about.
  • 20:44 --> 20:46Yeah, that was also during the
  • 20:46 --> 20:48day when he was just starting
  • 20:48 --> 20:49up. He was just just the breath
  • 20:49 --> 20:51of the stories that you covered.
  • 20:51 --> 20:53Like all of the big topics,
  • 20:53 --> 20:54all the big topics.
  • 20:54 --> 20:57You were there, right?
  • 20:57 --> 20:59I was enormously blessed by that
  • 20:59 --> 21:01because of that I've had this huge
  • 21:01 --> 21:04amount of you to wake up in the
  • 21:04 --> 21:05morning and always do something
  • 21:05 --> 21:08that you can think is interesting.
  • 21:08 --> 21:09For the most part.
  • 21:09 --> 21:10Obviously it doesn't always
  • 21:10 --> 21:12work out well, so how does
  • 21:12 --> 21:14that work practically for
  • 21:14 --> 21:16you? Well, a lot of those.
  • 21:16 --> 21:18A lot of the reporting was based on
  • 21:18 --> 21:20what was coming out in the journals.
  • 21:21 --> 21:23Is journals probably too large in extent
  • 21:23 --> 21:25and I think see now the major publications
  • 21:25 --> 21:28are backing off from just covering.
  • 21:28 --> 21:32You know what's new in Journal or JAMA or.
  • 21:32 --> 21:35Science or nature disk.
  • 21:35 --> 21:37The size is important.
  • 21:37 --> 21:43The but will you know if people know this?
  • 21:43 --> 21:45Press releases are given up in an
  • 21:45 --> 21:47embargoed fashion a few days in advance
  • 21:47 --> 21:49so that scientists can excuse me so
  • 21:49 --> 21:51the reporters can get a chance to get
  • 21:51 --> 21:54up to speed on the story before they
  • 21:54 --> 21:56have to write it or broadcast it.
  • 21:56 --> 21:57But that also has the effect
  • 21:57 --> 21:59of at 2:00 PM on Thursday.
  • 21:59 --> 22:01If a story, say in science,
  • 22:01 --> 22:03it'll come out on every broadcast
  • 22:03 --> 22:04and print medium,
  • 22:04 --> 22:07and as a result it looks like it's news.
  • 22:07 --> 22:09But of course anybody in the field
  • 22:09 --> 22:11will have heard about this is a
  • 22:11 --> 22:12conference and talking like sponsor,
  • 22:12 --> 22:13yeah, but
  • 22:13 --> 22:15it's been going on for a long
  • 22:15 --> 22:17time, but this is when it
  • 22:17 --> 22:18becomes official. News.
  • 22:19 --> 22:22So how do you? How do you manage that?
  • 22:22 --> 22:26So I just want to return to the AIDS crisis.
  • 22:26 --> 22:28So, so here you're you're reading
  • 22:28 --> 22:30reports of the death toll rising,
  • 22:30 --> 22:33or maybe giving those reports yourself,
  • 22:33 --> 22:37sure, and how? How do you know?
  • 22:37 --> 22:38Where to go after that?
  • 22:38 --> 22:40Like how do you find?
  • 22:40 --> 22:42How do you find groups to speak with?
  • 22:42 --> 22:45How do you select what scientists to go and
  • 22:45 --> 22:46speak with? Well, it was.
  • 22:46 --> 22:49It was pretty obvious that there were
  • 22:49 --> 22:52there weren't that many scientists in the.
  • 22:52 --> 22:54In the field, who really cared about
  • 22:54 --> 22:57it so he wasn't hard or doctors
  • 22:57 --> 23:00under the one of you in the building
  • 23:00 --> 23:03where we're doing this podcast?
  • 23:03 --> 23:06As I just saw Jerry Friedlander,
  • 23:06 --> 23:08who is a hero of HIV, AIDS,
  • 23:08 --> 23:12and I started interviewing him in the 1980s.
  • 23:12 --> 23:14He was in the Bronx when there
  • 23:14 --> 23:16was this horrible epidemic among
  • 23:16 --> 23:19Ivy drug users and their spouses,
  • 23:19 --> 23:22an children, an he since done
  • 23:22 --> 23:24marvelous work in South Africa with.
  • 23:24 --> 23:26HIV, AIDS and tuberculosis,
  • 23:26 --> 23:27and he continues.
  • 23:27 --> 23:29I mean, she's here today.
  • 23:29 --> 23:31Usually he's in South Africa,
  • 23:31 --> 23:33so he was here and they're like, yeah,
  • 23:33 --> 23:37they just signed who just saw a
  • 23:37 --> 23:41few minutes ago? Turnovers. Yeah,
  • 23:41 --> 23:45so you're going all over the US all over
  • 23:45 --> 23:46the world warning world.
  • 23:46 --> 23:48Yeah, I was sure I would.
  • 23:48 --> 23:51NBC was very good about that.
  • 23:51 --> 23:53Sending me to Africa and going at the
  • 23:53 --> 23:56beginning going to Haiti 1st and then
  • 23:56 --> 23:58Africa was very tough because they
  • 23:58 --> 24:01everybody didn't want to be blamed
  • 24:01 --> 24:03for this disease and they it was.
  • 24:03 --> 24:05It was highly stigmatized as well.
  • 24:05 --> 24:08What do you mean like the
  • 24:08 --> 24:09government or anything?
  • 24:09 --> 24:10The government certainly ANAN,
  • 24:10 --> 24:14but finally it would. In our first.
  • 24:14 --> 24:17What when I first went to Haiti?
  • 24:17 --> 24:22Which you know this thing came up where.
  • 24:22 --> 24:24Doctors were seeing people mostly in
  • 24:24 --> 24:28New York and in Miami, who were Haitians?
  • 24:28 --> 24:29What originally was?
  • 24:29 --> 24:34It was gaming and drug users an.
  • 24:34 --> 24:35And there was no,
  • 24:35 --> 24:37they didn't have any risk factors.
  • 24:37 --> 24:39Nobody knew that there was a massive
  • 24:39 --> 24:41epidemic going in Haiti at the time,
  • 24:41 --> 24:43but I went to Haiti and was
  • 24:43 --> 24:45followed around by the secret
  • 24:45 --> 24:47police and nobody would talk to me.
  • 24:47 --> 24:49But of course I could talk to
  • 24:49 --> 24:51Haitian doctors in the United States.
  • 24:51 --> 24:53But there was enormous discrimination
  • 24:53 --> 24:54against station.
  • 24:54 --> 24:55So I did a piece in 1983 where
  • 24:55 --> 24:57we had Haitian saying that they
  • 24:57 --> 24:59were fired just because they were
  • 25:00 --> 25:01Haitians and families were afraid
  • 25:01 --> 25:04that they would get AIDS from.
  • 25:04 --> 25:06They were fired in the US because reasons.
  • 25:08 --> 25:10Well, so that's an aspect of
  • 25:10 --> 25:12medicine that we're only starting
  • 25:12 --> 25:14as physicians to talk about.
  • 25:14 --> 25:17You know, the stigma and the social factors.
  • 25:17 --> 25:19Like in psychiatry we have this
  • 25:19 --> 25:21biopsychosocial model where for
  • 25:21 --> 25:23every patient we have to try to
  • 25:23 --> 25:25consider the social situation.
  • 25:25 --> 25:28And so you were reporting on a lot of this
  • 25:28 --> 25:31in from a medical perspective, right?
  • 25:31 --> 25:33'cause this is what it was,
  • 25:33 --> 25:36a medical, introspective and one of
  • 25:36 --> 25:39the things I went to San Francisco
  • 25:39 --> 25:42a lot to do the reporting an.
  • 25:42 --> 25:44And I wasn't the only Reporter who
  • 25:44 --> 25:47did that for the domestic reporting
  • 25:47 --> 25:49on the emerging azik epidemic.
  • 25:49 --> 25:51And the reason was San Francisco
  • 25:51 --> 25:54had a large gay community of young
  • 25:54 --> 25:56men who had recently come out,
  • 25:56 --> 25:58and they were very politically powerful.
  • 25:58 --> 26:01There was, they had 70,000 registered
  • 26:01 --> 26:03voters in a city of 600,000,
  • 26:03 --> 26:06so they were a considerable political force.
  • 26:06 --> 26:07And as a result,
  • 26:07 --> 26:09they weren't as afraid an to
  • 26:10 --> 26:11be open and talk.
  • 26:11 --> 26:13And then San Francisco General
  • 26:13 --> 26:15opened its dedicated AIDS units,
  • 26:15 --> 26:18the inpatient and outpatient in 1983.
  • 26:18 --> 26:21And so we go even go in there.
  • 26:21 --> 26:25If I there were big institutions in New York,
  • 26:25 --> 26:28want some of which refused to
  • 26:28 --> 26:30treat people with HIV AIDS,
  • 26:30 --> 26:33which then you can argue about all the
  • 26:33 --> 26:36ethics of that others like Bellevue,
  • 26:36 --> 26:40which were just completely overrun the.
  • 26:40 --> 26:42People who did their residencies,
  • 26:42 --> 26:44especially in internal medicine,
  • 26:44 --> 26:47but it almost anything and in the
  • 26:47 --> 26:4980s through the discovery of the good
  • 26:49 --> 26:52drugs in the mid 90s at Bellevue,
  • 26:52 --> 26:54which is a great residency,
  • 26:54 --> 26:56much sought after.
  • 26:56 --> 26:58So almost nothing but AIDS,
  • 26:58 --> 27:00so they were doing things like treating
  • 27:00 --> 27:02these rare opportunistic infections
  • 27:02 --> 27:04which in most situations you would
  • 27:04 --> 27:06never see an American medical practice.
  • 27:06 --> 27:08And as a whole they treated well.
  • 27:08 --> 27:11How did I let me finish on something?
  • 27:11 --> 27:14So a lot of these hospitals and I would
  • 27:14 --> 27:17not let camera crews in because they
  • 27:17 --> 27:20did not want the ones that did treat it.
  • 27:20 --> 27:21People with aids?
  • 27:21 --> 27:21They didn't.
  • 27:21 --> 27:24They wouldn't let you in there because
  • 27:24 --> 27:26they didn't want their other patients
  • 27:26 --> 27:28to know that they were raised.
  • 27:28 --> 27:30And in the war, oh.
  • 27:30 --> 27:31So they didn't.
  • 27:31 --> 27:34We couldn't take a TV crew in
  • 27:34 --> 27:35just most hospitals.
  • 27:36 --> 27:37So you couldn't show people
  • 27:37 --> 27:38with the situation was
  • 27:38 --> 27:40like yeah, but you couldn't.
  • 27:40 --> 27:42San Francisco and I did sometimes
  • 27:42 --> 27:44in New York we there were certain
  • 27:44 --> 27:46places like Albert Einstein was much
  • 27:46 --> 27:48more open about it than other places,
  • 27:48 --> 27:49but most most places would not
  • 27:49 --> 27:51let it TV anywhere near or
  • 27:51 --> 27:53whether people talk about it.
  • 27:53 --> 27:54Talk about it.
  • 27:54 --> 27:56I mean they would show up at conferences
  • 27:56 --> 27:58and you could interview them there,
  • 27:58 --> 28:00but not in the context of their hospital.
  • 28:01 --> 28:04So I when I rotated through an
  • 28:04 --> 28:06infectious disease, units just as
  • 28:06 --> 28:08part of my medical internship,
  • 28:08 --> 28:11some of my attendings were either Chinese
  • 28:11 --> 28:14or already attendings during that period
  • 28:14 --> 28:17and asking them questions about this crisis.
  • 28:17 --> 28:20And you know how the public dealt with it,
  • 28:20 --> 28:23how the government of the FDA
  • 28:23 --> 28:26dealt with it on the NHS with it?
  • 28:26 --> 28:28It's a very emotionally charged
  • 28:28 --> 28:33still even you know, 35 years later.
  • 28:33 --> 28:36Situation, so I'm curious how.
  • 28:36 --> 28:38How you navigated those emotions
  • 28:38 --> 28:40for yourself, like how you managed
  • 28:40 --> 28:43reporting on something so emotionally
  • 28:43 --> 28:44provocative and well, it was.
  • 28:44 --> 28:46It was an
  • 28:46 --> 28:49after a while. My biggest fight with
  • 28:49 --> 28:52this was to get stories on the air,
  • 28:52 --> 28:54because when it became there
  • 28:54 --> 28:56were these big periods in the
  • 28:56 --> 28:58history of the AIDS epidemic.
  • 28:58 --> 29:00HIV AIDS epidemic.
  • 29:00 --> 29:03One is when Rock Hudson got sick and
  • 29:03 --> 29:06suddenly this gorgeous leading man.
  • 29:06 --> 29:09Why did so? Nobody knew he was gay and
  • 29:09 --> 29:12Magic Johnson in 1991 and other celebrities.
  • 29:12 --> 29:14So these you can see big spikes and
  • 29:14 --> 29:17interest in a disease at those times.
  • 29:17 --> 29:18But for the most part,
  • 29:18 --> 29:20especially especially before Rock Hudson,
  • 29:20 --> 29:22it was there wasn't as much interest
  • 29:22 --> 29:25in it as I would have liked.
  • 29:25 --> 29:27I would keep coming back and trying to
  • 29:27 --> 29:30do stories and producers would say no,
  • 29:30 --> 29:33you know, go do a story on breast
  • 29:33 --> 29:36cancer or go do a story about.
  • 29:36 --> 29:38Chronic fatigue syndrome or something like
  • 29:38 --> 29:42that? Kind of critique central enough, right?
  • 29:42 --> 29:44What was their logic? Just they wanted
  • 29:44 --> 29:46more diverse. Well, they want people
  • 29:46 --> 29:50to watch the TV and the man putting on
  • 29:50 --> 29:52pictures of men who have sex with men or.
  • 29:55 --> 29:56People who inject drugs does
  • 29:56 --> 29:58not attract the audience that
  • 29:58 --> 30:00the television network wants.
  • 30:01 --> 30:04Interesting, well at the same time though,
  • 30:04 --> 30:06the presence of publicity.
  • 30:06 --> 30:08And and you know,
  • 30:08 --> 30:09obviously I'm talking as someone
  • 30:09 --> 30:10who wasn't there and you know,
  • 30:10 --> 30:13I'm obviously not a scholar of this moment,
  • 30:13 --> 30:15but. Having the publicity allowed the
  • 30:15 --> 30:18science to catch up to the epidemic
  • 30:18 --> 30:20and allowed these politically active
  • 30:20 --> 30:23groups to be able to help sculpt policy.
  • 30:23 --> 30:25And so it was
  • 30:25 --> 30:29a great article. By Alan Brandt who's
  • 30:29 --> 30:32a historian of medicine at Harvard.
  • 30:32 --> 30:35It was in the New England Journal of Medicine
  • 30:35 --> 30:38called How Aids created Global Health,
  • 30:38 --> 30:40and I highly recommend that
  • 30:40 --> 30:43you or your listeners check out
  • 30:43 --> 30:45that that article because.
  • 30:45 --> 30:48Many things that we take for granted today,
  • 30:48 --> 30:49such as patient activism,
  • 30:49 --> 30:52an the need to think about other
  • 30:52 --> 30:54people in a cooperative way and not.
  • 30:57 --> 30:59Not necessarily a condescending way which
  • 30:59 --> 31:01a lot of international health before the
  • 31:01 --> 31:03HIV epidemic was very condescending.
  • 31:03 --> 31:06You know we are donors would
  • 31:06 --> 31:08give with what they would give
  • 31:08 --> 31:10and it was preceded by a period.
  • 31:10 --> 31:13There was even worse which was
  • 31:13 --> 31:14Tropical Medicine where we would.
  • 31:14 --> 31:16You're protecting our own people
  • 31:16 --> 31:18or our troops or whatever.
  • 31:18 --> 31:21So that has to do with the
  • 31:21 --> 31:24history of public health. But the.
  • 31:24 --> 31:26AIDS made everything different.
  • 31:26 --> 31:27Was very clear that there
  • 31:27 --> 31:29was this massive epidemic,
  • 31:29 --> 31:30an one of the.
  • 31:30 --> 31:34And it it's and there's a lot of
  • 31:34 --> 31:36fear right now that there's going
  • 31:36 --> 31:40to be a second wave of of because
  • 31:40 --> 31:43there's 23.3 million people on
  • 31:43 --> 31:45antiretroviral drugs in the world
  • 31:45 --> 31:47was an astounding achievement,
  • 31:47 --> 31:47and the.
  • 31:50 --> 31:52If and Trump has reauthorized the
  • 31:52 --> 31:53Trump administration is reauthorized,
  • 31:53 --> 31:55PEPFAR, which is the major
  • 31:55 --> 31:57contributor for those bills.
  • 31:57 --> 31:59There are other donors as well,
  • 31:59 --> 32:01but the biggest chunk of that
  • 32:01 --> 32:03comes from the US government,
  • 32:03 --> 32:05and he proposes cutting into
  • 32:05 --> 32:07budget for it every year.
  • 32:07 --> 32:09An you people here in the Yale
  • 32:09 --> 32:12School of Public Health and others
  • 32:12 --> 32:14have done calculations you can do
  • 32:14 --> 32:16just very cold calculations for
  • 32:16 --> 32:18every $1,000,000 that gets cut back.
  • 32:18 --> 32:22How many million people are going to die?
  • 32:22 --> 32:22Because there?
  • 32:22 --> 32:23There's no cure,
  • 32:23 --> 32:25and as a result there's all these
  • 32:25 --> 32:27people that are going to die
  • 32:27 --> 32:28if they don't get their drugs.
  • 32:29 --> 32:31So that's the intersection of
  • 32:31 --> 32:33advocacy and policy. Then write an
  • 32:33 --> 32:35in that that came about them into.
  • 32:35 --> 32:38Don't forget the. Larry Kramer,
  • 32:38 --> 32:40who I become I became very close
  • 32:40 --> 32:42to the famous AIDS activist who
  • 32:42 --> 32:44started the gay men's health crisis,
  • 32:44 --> 32:47first as a support group in
  • 32:47 --> 32:491981 and he started out.
  • 32:49 --> 32:52Screaming and yelling at there was this
  • 32:52 --> 32:54horrible thing going on and he was.
  • 32:54 --> 32:56He had enormous pushback from other members
  • 32:56 --> 32:59of the gay community that he was approved.
  • 32:59 --> 33:01He wanted to close down the bath
  • 33:01 --> 33:03houses that places where men went
  • 33:03 --> 33:06to have ****** and that was a huge
  • 33:06 --> 33:08part of the early years was fight
  • 33:08 --> 33:10within the gay community over whether
  • 33:10 --> 33:13to close down the bath houses and
  • 33:13 --> 33:16Kramer then got tired of the just the
  • 33:16 --> 33:19advocacy and he started acting up.
  • 33:19 --> 33:22An act up accomplished a lot of
  • 33:22 --> 33:24called attention to a lot of things,
  • 33:24 --> 33:27but then act up spun off yet another group
  • 33:27 --> 33:29called the Treatment Action Coalition,
  • 33:29 --> 33:31which exists to this day and
  • 33:31 --> 33:32as marvelous work,
  • 33:32 --> 33:34because what they did was they learn
  • 33:34 --> 33:36they became as knowledgeable about
  • 33:36 --> 33:39the disease as many of the scientists,
  • 33:39 --> 33:42so they thought and it was a big,
  • 33:42 --> 33:44big fight to get a seat at the
  • 33:44 --> 33:47table on FDA and NIH review panels.
  • 33:47 --> 33:49And but they got it.
  • 33:49 --> 33:51And it made a big difference,
  • 33:51 --> 33:53and now it's standard procedure.
  • 33:53 --> 33:54This consumer representatives and
  • 33:54 --> 33:56all those things. But it didn't.
  • 33:56 --> 33:58It wasn't always that way.
  • 33:58 --> 34:00And then the even people who were
  • 34:00 --> 34:03working full time on the problem at the
  • 34:03 --> 34:05NIH were disgusted at the idea none.
  • 34:05 --> 34:06Now that they were homophobic,
  • 34:06 --> 34:08but that non scientists would
  • 34:08 --> 34:09come into the room.
  • 34:09 --> 34:12But if you talk to some of these non
  • 34:12 --> 34:14scientists they actually had this,
  • 34:14 --> 34:17you know there's.
  • 34:17 --> 34:18Cat's encyclopedic knowledge.
  • 34:18 --> 34:18That's
  • 34:18 --> 34:20so I'm turning around my head
  • 34:20 --> 34:23around this as as you know,
  • 34:23 --> 34:25someone that knows a little
  • 34:25 --> 34:27bit about the science but very
  • 34:27 --> 34:29little about the you know,
  • 34:29 --> 34:31the the advocacy component,
  • 34:31 --> 34:34and so these people have got together
  • 34:34 --> 34:36and act up an they engaged media.
  • 34:36 --> 34:38They staged protests, Anaza results.
  • 34:38 --> 34:42They were able to curb the public opinion,
  • 34:42 --> 34:44which then also changed the way
  • 34:44 --> 34:45science functions, right?
  • 34:45 --> 34:47And there were.
  • 34:47 --> 34:51Yes, because one of the big questions.
  • 34:51 --> 34:53Which goes back to what I was.
  • 34:53 --> 34:56I had mentioned Mary Lasker, Mary Lasker's,
  • 34:56 --> 34:58and the 1971 War on Cancer was
  • 34:58 --> 35:01based on the notion that we don't.
  • 35:01 --> 35:03We can't just sit around
  • 35:03 --> 35:04and wait for basic research.
  • 35:04 --> 35:07We have to have targeted research and
  • 35:07 --> 35:09that's huge policy argument about
  • 35:09 --> 35:11where it where does work come from.
  • 35:11 --> 35:13But but.
  • 35:13 --> 35:16At some point you have to say that we
  • 35:16 --> 35:18have this massive public health problem.
  • 35:18 --> 35:20We have to just worry about
  • 35:20 --> 35:22this and think about things that
  • 35:22 --> 35:24will make a difference in this.
  • 35:24 --> 35:25Anne Marie lost,
  • 35:25 --> 35:28we wanted to do that with cancer and
  • 35:28 --> 35:31it turned out it was way too early.
  • 35:31 --> 35:33Nobody even when in 1971 nobody
  • 35:33 --> 35:34even knew
  • 35:34 --> 35:36what caused cancer. I mean it was
  • 35:36 --> 35:38not. Uncle genes were not discovered.
  • 35:38 --> 35:40They weren't discovered until 1976 in
  • 35:40 --> 35:43chickens and then in 1981 and human beings.
  • 35:43 --> 35:45So that was a lot of.
  • 35:45 --> 35:47Time passed and everybody the money
  • 35:47 --> 35:50it was was money and it did support
  • 35:50 --> 35:52basic research that led to those
  • 35:52 --> 35:54discoveries which are just now
  • 35:54 --> 35:57starting to lead to drugs and well
  • 35:57 --> 35:58the precision medicine you know.
  • 35:58 --> 36:01Oncology is the poster child of precision
  • 36:01 --> 36:03medicine nowadays right? Also the actual
  • 36:03 --> 36:05numbers of people who get help or
  • 36:05 --> 36:07are much lower than you would think
  • 36:07 --> 36:09about because one of the difficulties
  • 36:10 --> 36:12about doing a story about something
  • 36:12 --> 36:14like a new immunotherapy for cancer
  • 36:14 --> 36:16is you find somebody who was.
  • 36:16 --> 36:19Almost dead yesterday and is now
  • 36:19 --> 36:21is running the marathon and yeah,
  • 36:21 --> 36:24but it turns out that only 12% of
  • 36:24 --> 36:25people who get immunotherapy's
  • 36:25 --> 36:28overall show any kind of response
  • 36:28 --> 36:30that I'm talking about not talking
  • 36:30 --> 36:32about surviving for years.
  • 36:32 --> 36:34I'm just any kind of response,
  • 36:34 --> 36:36let alone people who were.
  • 36:38 --> 36:39What you would call a cure it
  • 36:39 --> 36:41if you have go for several years
  • 36:41 --> 36:43without recurrence? Well, so
  • 36:43 --> 36:46how do you view so one of the
  • 36:46 --> 36:48things I've observed is that.
  • 36:48 --> 36:50More specifically in in psychiatry,
  • 36:50 --> 36:52my field every five to 10 years.
  • 36:52 --> 36:54Someone writes this paper that
  • 36:54 --> 36:56we are about to enter the
  • 36:56 --> 36:58Golden age of psychiatry, right?
  • 36:58 --> 37:00See a lot of Golden Age is
  • 37:00 --> 37:02a lot of goals, and
  • 37:02 --> 37:05then you see it in every field of medicine
  • 37:05 --> 37:08is a world where about we're about there,
  • 37:08 --> 37:12I mean, and it's absolutely fascinating.
  • 37:12 --> 37:14About how long things can take Francis
  • 37:14 --> 37:18Collins, who's now the director of
  • 37:18 --> 37:20the National Institutes of Health?
  • 37:20 --> 37:23As head of the Human Genome Project
  • 37:23 --> 37:24discovered, the gene for cystic
  • 37:24 --> 37:27fibrosis in I have to look it up.
  • 37:27 --> 37:28I don't have it.
  • 37:28 --> 37:31I thought I had, but it was,
  • 37:31 --> 37:32I think in the 1980s,
  • 37:32 --> 37:34before the Genome project.
  • 37:34 --> 37:35Yeah before long because yeah,
  • 37:35 --> 37:38in the days when it took forever,
  • 37:38 --> 37:40but it was just this last week
  • 37:40 --> 37:42that the FDA approved a gene
  • 37:42 --> 37:44based drug for cystic fibrosis.
  • 37:44 --> 37:46That seems to be truly effective.
  • 37:46 --> 37:46Oh, I
  • 37:46 --> 37:48hadn't heard of that.
  • 37:49 --> 37:52King, about decades between you and it
  • 37:52 --> 37:54looks so exciting when you and it's true,
  • 37:54 --> 37:56it was exciting to know that there
  • 37:56 --> 37:59was this gene. But at the time,
  • 37:59 --> 38:01kids with cystic fibrosis were
  • 38:01 --> 38:03living there be 6 or 7 you know.
  • 38:03 --> 38:05Now you have 40 and 50 year olds and
  • 38:05 --> 38:08it looks like they may soon have a
  • 38:08 --> 38:10completely normal life expectancy. So
  • 38:10 --> 38:12so this perennial question of the Golden Age.
  • 38:12 --> 38:14This is something that really
  • 38:14 --> 38:16fascinates me and I spend time
  • 38:16 --> 38:18agonizing over because a lot of it is,
  • 38:18 --> 38:21you know, science is based on this.
  • 38:21 --> 38:22Idea of of grants right?
  • 38:22 --> 38:24If you want to be an academic scientist,
  • 38:24 --> 38:25you write a grant for five years, right?
  • 38:25 --> 38:27And you say I'm going to do this.
  • 38:27 --> 38:29That and the other an at the
  • 38:29 --> 38:32end of five years, you know.
  • 38:32 --> 38:34Reflective scientists will be like did
  • 38:34 --> 38:36I actually accomplish those things and
  • 38:36 --> 38:39something that you know in your book
  • 38:39 --> 38:41is how after there is this increased
  • 38:41 --> 38:44funding for breast cancer or the NCI,
  • 38:44 --> 38:46the National Cancer Institute had
  • 38:46 --> 38:48their budget tripled or doubled.
  • 38:48 --> 38:51His order order of magnitude all of a sudden.
  • 38:51 --> 38:53All these scientists who were basic
  • 38:53 --> 38:55scientists began to be interested
  • 38:55 --> 38:56in a few sentences.
  • 38:56 --> 38:59At the end of their granite
  • 38:59 --> 39:00studying cancer right right?
  • 39:00 --> 39:00And
  • 39:00 --> 39:02you can do it, yeah?
  • 39:02 --> 39:05Is pretty easy as you know,
  • 39:05 --> 39:08as a scientist that to write those words in,
  • 39:08 --> 39:10because almost any basic science
  • 39:10 --> 39:13can be said to be relevant to the
  • 39:13 --> 39:15cancer problem because the cancer
  • 39:15 --> 39:18problem is how cells work, right?
  • 39:18 --> 39:21Yes, how does the body where? How does the
  • 39:21 --> 39:23body work and therefore you can
  • 39:23 --> 39:26make it an it's interesting,
  • 39:26 --> 39:28the immuno therapy stuff came
  • 39:28 --> 39:30from 2 lines of research.
  • 39:30 --> 39:32One was just really basic
  • 39:32 --> 39:34research immunology and mice.
  • 39:34 --> 39:35By James Allison.
  • 39:35 --> 39:38When when he was at Berkeley,
  • 39:38 --> 39:41now he's at MD Anderson an the
  • 39:41 --> 39:44the other came from a discovery.
  • 39:44 --> 39:47That was made very, very applied.
  • 39:47 --> 39:49An HIV discovery that when the HIV
  • 39:49 --> 39:52attacks the type of word but white
  • 39:52 --> 39:55blood cells called CD four cells.
  • 39:55 --> 39:57It doesn't just attach to
  • 39:57 --> 39:5911 protein on the surface,
  • 39:59 --> 40:00it attached.
  • 40:00 --> 40:03To a coreceptor an there was a
  • 40:03 --> 40:06study of sex workers female sex
  • 40:06 --> 40:10workers in Nairobi which found that.
  • 40:12 --> 40:13A very small percentage less
  • 40:13 --> 40:16than one by far of them,
  • 40:16 --> 40:18had unprotected sex with thousands
  • 40:18 --> 40:20of men who were infected and it
  • 40:20 --> 40:22never got the diseases themselves.
  • 40:22 --> 40:24And it turned out that they had
  • 40:24 --> 40:27a defect in this coreceptor Ann.
  • 40:27 --> 40:29This is the Co receptor that makes up
  • 40:29 --> 40:32what the basis for immunotherapy for cancer.
  • 40:32 --> 40:35Now we have these two 2
  • 40:35 --> 40:36lines of research that say
  • 40:36 --> 40:38you never know, right?
  • 40:38 --> 40:39Yeah, exactly unknown unknown.
  • 40:39 --> 40:41Yeah you were working
  • 40:41 --> 40:43with mice in a lab about.
  • 40:43 --> 40:46Immunology is is one thing and but also
  • 40:46 --> 40:48studying Kenyan sex workers is another.
  • 40:48 --> 40:51Another thing is why is he why
  • 40:51 --> 40:52somebody bothering to do this?
  • 40:52 --> 40:55Well it turns out that you know
  • 40:55 --> 40:57in the world one human being,
  • 40:57 --> 40:59the Berlin patient has been cured
  • 40:59 --> 41:01of HIV and it was because he
  • 41:01 --> 41:03got a transplant from somebody
  • 41:03 --> 41:05who had this defective receptor
  • 41:05 --> 41:07as a treatment for leukemia.
  • 41:07 --> 41:09So he is now cured of HIV.
  • 41:09 --> 41:11Kind of incidentally yeah I saw
  • 41:11 --> 41:12that but unfortunately it's
  • 41:12 --> 41:14not something you want to.
  • 41:14 --> 41:17Do is routinely, for you know,
  • 41:17 --> 41:19the 35 million people in the
  • 41:19 --> 41:21world who are moving with
  • 41:21 --> 41:23HIV, but my head well.
  • 41:23 --> 41:25So yes, I I fully.
  • 41:25 --> 41:26I fully accept that.
  • 41:26 --> 41:28You know serendipity is
  • 41:28 --> 41:30a large part of science.
  • 41:30 --> 41:32And embracing these serendipitous
  • 41:32 --> 41:34discoveries often leads to.
  • 41:34 --> 41:37Wonderful things like the unknown unknown.
  • 41:37 --> 41:40So yeah, there's a lot of potential there.
  • 41:40 --> 41:43However, one of the things that
  • 41:43 --> 41:46makes me anxious is the selling of
  • 41:46 --> 41:49science in a way that isn't completely
  • 41:49 --> 41:51driven by the science itself.
  • 41:51 --> 41:52O for example,
  • 41:52 --> 41:55the the idea of selling your work is
  • 41:55 --> 41:58being curated for a specific disease
  • 41:58 --> 42:00when it's not directly related.
  • 42:00 --> 42:03You know there is some salesmanship
  • 42:03 --> 42:04in grantsmanship.
  • 42:04 --> 42:07And you know, in order to get funded,
  • 42:07 --> 42:09you have to get people excited.
  • 42:09 --> 42:10However, this Golden age question.
  • 42:15 --> 42:16Sorry, go ahead
  • 42:16 --> 42:18and now the goal it well.
  • 42:18 --> 42:20One of the things that happens if you talk
  • 42:20 --> 42:22about there are lobbyists in Washington
  • 42:22 --> 42:24who work on behalf of organizations
  • 42:24 --> 42:26like the American Association for the
  • 42:26 --> 42:29Advancement of Science or the American
  • 42:29 --> 42:31Association of Universities. Anne.
  • 42:31 --> 42:35The way that they have ways of doing it,
  • 42:35 --> 42:37which is they tie it all it gets
  • 42:37 --> 42:39tide up with other social service
  • 42:39 --> 42:43programs and as a result it lifts the
  • 42:43 --> 42:45tide and then then then scientists.
  • 42:45 --> 42:48Add places like the NIH or the National
  • 42:48 --> 42:51Science Foundation can make the decision
  • 42:51 --> 42:54about what where the money should go,
  • 42:54 --> 42:56and it doesn't just go to silly
  • 42:56 --> 42:59projects that are designed to try to
  • 42:59 --> 43:02cure diseases kind of offbeat way,
  • 43:02 --> 43:05but a lot of stuff.
  • 43:05 --> 43:07As you know, does get published.
  • 43:07 --> 43:09It never gets replicated,
  • 43:09 --> 43:11replicated or reproduced or refer to
  • 43:11 --> 43:14and just goes off in the deep end,
  • 43:14 --> 43:16and there's a lot of concern about that
  • 43:16 --> 43:19and exactly how you steer this gigantic
  • 43:19 --> 43:21ship and the scientific enterprise is
  • 43:21 --> 43:23just growing so rapidly it if you look
  • 43:23 --> 43:26at the charts of the number of journals,
  • 43:26 --> 43:28the number of people working in
  • 43:28 --> 43:29science and everything else.
  • 43:29 --> 43:32So any argument that we're in an age
  • 43:32 --> 43:35that's not a Golden age where we are.
  • 43:35 --> 43:37Where the public doesn't support size.
  • 43:37 --> 43:38I don't buy into that,
  • 43:38 --> 43:39only we have we
  • 43:39 --> 43:40have. So you think
  • 43:40 --> 43:41this is the Golden age thing?
  • 43:41 --> 43:43Yeah, we're definitely the
  • 43:43 --> 43:44goal of the things that.
  • 43:45 --> 43:47I hear about that are going on on this
  • 43:47 --> 43:49campus and others and other institutes
  • 43:49 --> 43:51around the country are just astounding
  • 43:51 --> 43:54because the tools are getting so much better.
  • 43:54 --> 43:57The Genome Project is the obvious one.
  • 43:57 --> 44:00You know. It used to take months and months.
  • 44:00 --> 44:04I mean I remember. The.
  • 44:04 --> 44:07There aren't very many single.
  • 44:07 --> 44:10Based as you know, the single gene disease
  • 44:10 --> 44:14is caused by a defect in one gene or mute.
  • 44:14 --> 44:16An alteration in one gene,
  • 44:16 --> 44:19but the first one that we discovered
  • 44:19 --> 44:20was Huntington's disease,
  • 44:20 --> 44:23which was in 1984.
  • 44:23 --> 44:25And it took them until 1994 to
  • 44:25 --> 44:26actually sequence that gene because
  • 44:26 --> 44:28the technology was so crude.
  • 44:28 --> 44:30Now. Now if somebody knew
  • 44:30 --> 44:31the location of that gene,
  • 44:31 --> 44:33they could hear it, Yale,
  • 44:33 --> 44:34it would put it outside.
  • 44:34 --> 44:37They could do it in a much even faster way,
  • 44:37 --> 44:40but usually what they do is they put it
  • 44:40 --> 44:42outside their door in a bucket like you
  • 44:42 --> 44:45see outside of your doctors office for
  • 44:45 --> 44:47blood and urine samples is picked up.
  • 44:47 --> 44:50It's taken to a gene sequencing and they get
  • 44:50 --> 44:53it back in the morning on their computer.
  • 44:53 --> 44:56And they can compare it to every
  • 44:56 --> 44:58known gene sequence in every
  • 44:58 --> 45:00animal creature on Earth an.
  • 45:00 --> 45:01At best,
  • 45:01 --> 45:02pretty Golden age. Yeah,
  • 45:02 --> 45:04that's pretty Golden age and and
  • 45:04 --> 45:05what's happening now is one
  • 45:05 --> 45:07of the biggest problems is
  • 45:07 --> 45:08there's so much data coming in.
  • 45:08 --> 45:11How do you deal with all the data?
  • 45:11 --> 45:12There's so much information? Well,
  • 45:12 --> 45:14what are your thoughts on neuroscience then?
  • 45:14 --> 45:16Like how do you view that?
  • 45:16 --> 45:18Our understanding of the brain in relation
  • 45:18 --> 45:20to these? Otherwise I think we have a
  • 45:20 --> 45:22long way to go and understanding science.
  • 45:22 --> 45:27What makes. It is very interesting if you.
  • 45:27 --> 45:30Think about evolution and Richard Dawkins
  • 45:30 --> 45:34who's one of my favorite writers of
  • 45:34 --> 45:37all these brilliant actually written.
  • 45:37 --> 45:40He but. And he he gets pounced on
  • 45:40 --> 45:44all the time by the religious right,
  • 45:44 --> 45:47because of he thinks that religion is a
  • 45:47 --> 45:49meme term that he invented, but it's.
  • 45:49 --> 45:52But it's a meme is a conscious thing.
  • 45:52 --> 45:55It's not a gene and he and he
  • 45:55 --> 45:57constantly says that we've developed a
  • 45:57 --> 46:00consciousness we because we have a brain.
  • 46:00 --> 46:01It came from evolution.
  • 46:01 --> 46:03But we don't understand it.
  • 46:03 --> 46:05We don't have the mechanism
  • 46:05 --> 46:06to understand our own brains.
  • 46:06 --> 46:09And as an example of why everything is
  • 46:09 --> 46:12not driven by Darwinian natural selection,
  • 46:12 --> 46:14he says, well, we wouldn't have.
  • 46:14 --> 46:16Option one practice contraception
  • 46:16 --> 46:18if we wanted to just increase our
  • 46:18 --> 46:19our genes in the world.
  • 46:19 --> 46:21Well so so I think his
  • 46:21 --> 46:23arguments pretty sound though.
  • 46:23 --> 46:25So like why would we suppose that our
  • 46:25 --> 46:27brains evolved to understand the brain?
  • 46:27 --> 46:29No, I don't think we have the
  • 46:29 --> 46:31capacity to do that. So then.
  • 46:31 --> 46:34So then what direction like in terms of
  • 46:34 --> 46:36the Golden age of neuroscience then.
  • 46:36 --> 46:38So so there have been many stories
  • 46:38 --> 46:40purporting that this decade of the brain,
  • 46:40 --> 46:42for example, right like you know,
  • 46:42 --> 46:45we're going to devote a lot of money to this,
  • 46:45 --> 46:47like we did with the.
  • 46:47 --> 46:49Human genome and in 10 years will
  • 46:49 --> 46:51shake her hand and what happened?
  • 46:51 --> 46:53No, not much right.
  • 46:53 --> 46:54There was a decade
  • 46:54 --> 46:56of the brain. Sounds like a good idea
  • 46:56 --> 46:59and I'm sure they pay for decent science.
  • 46:59 --> 47:01I'm not up on the literature
  • 47:01 --> 47:04on that. I don't know what to tell
  • 47:04 --> 47:06ya to say that that we learned.
  • 47:06 --> 47:08You know nothing is obviously false.
  • 47:08 --> 47:11I mean we know wealth of information about
  • 47:11 --> 47:13the brain, like how neurons function,
  • 47:13 --> 47:15how they organized you, know sub circuits
  • 47:15 --> 47:17and circuits and networks and systems.
  • 47:17 --> 47:20Throughout the brain, but are we able to
  • 47:20 --> 47:23bring that to the level of healthcare?
  • 47:23 --> 47:25Not quite yet right?
  • 47:25 --> 47:27And so that's the question then,
  • 47:27 --> 47:30is like something that I've been musing over.
  • 47:30 --> 47:32Is all of these movements.
  • 47:32 --> 47:36I hope that I don't mean that in a
  • 47:36 --> 47:39derogatory way to say like the AIDS.
  • 47:39 --> 47:42Advocates were like a movement, but I don't.
  • 47:42 --> 47:44I don't know another word to
  • 47:44 --> 47:46describe that like that movement.
  • 47:46 --> 47:48The cancer movement,
  • 47:48 --> 47:50specifically the breast cancer movement.
  • 47:50 --> 47:53These people were able to create a
  • 47:53 --> 47:56lot of enthusiasm which then trickled
  • 47:56 --> 47:58into the scientific enterprise
  • 47:58 --> 48:00in the form of funding,
  • 48:00 --> 48:03which then allows treatments to
  • 48:03 --> 48:05eventually be brought to market.
  • 48:05 --> 48:07Which one is lucky?
  • 48:07 --> 48:08I mean,
  • 48:08 --> 48:09there's feel like,
  • 48:09 --> 48:12yeah, but it also allows the
  • 48:12 --> 48:13scientific understanding.
  • 48:13 --> 48:17Sometimes that doesn't wait to treatments.
  • 48:17 --> 48:19And it's not a bad thing.
  • 48:19 --> 48:21I mean, and there still is support
  • 48:21 --> 48:23despite everything else for the.
  • 48:23 --> 48:27Like the wonderful things that say,
  • 48:27 --> 48:30Carl Zimmer writes about about the
  • 48:30 --> 48:32interaction of a lichen and fungus and
  • 48:32 --> 48:36sure or the which is terrifying. By the
  • 48:36 --> 48:40way they are. Or or or
  • 48:40 --> 48:42does this interest that we all have in in
  • 48:42 --> 48:44the origin of human population migrations?
  • 48:44 --> 48:46That's not going to. That probably is
  • 48:46 --> 48:48not going to tell us anything that's
  • 48:48 --> 48:50going to be useful in the clinic,
  • 48:50 --> 48:53but I think it should be supported not
  • 48:53 --> 48:55just because I like to read about it,
  • 48:55 --> 48:57but I think, you know,
  • 48:57 --> 48:58tells us more about who
  • 48:58 --> 49:00we are and it's absolutely
  • 49:00 --> 49:01fascinating. So any knowledge
  • 49:01 --> 49:03is good knowledge, then yeah, well,
  • 49:03 --> 49:04any yeah? Any knowledge that is not
  • 49:04 --> 49:07used for destructive purposes as good
  • 49:07 --> 49:08knowledge? Napalm? It's not
  • 49:08 --> 49:09good. No, I don't think.
  • 49:09 --> 49:11I don't think Napalm is good
  • 49:11 --> 49:12under any circumstances,
  • 49:12 --> 49:16and it goes for a lot of other other things.
  • 49:16 --> 49:18But if you're thinking about.
  • 49:18 --> 49:21The scientific enterprise.
  • 49:21 --> 49:24Yeah, I get back to these Pew surveys.
  • 49:24 --> 49:27Science has never been held in higher regard.
  • 49:27 --> 49:30Let me people there are these awful
  • 49:30 --> 49:33things that are going on like.
  • 49:33 --> 49:34Cuts in environmental regulations
  • 49:34 --> 49:36that are based on pseudoscience that,
  • 49:36 --> 49:39but a lot of that is a political decision.
  • 49:39 --> 49:42Are we willing to be like India and
  • 49:42 --> 49:44China and breed really horrible air so
  • 49:44 --> 49:47that some people can make more profits?
  • 49:47 --> 49:50Or are we?
  • 49:50 --> 49:52Those are political ideas and the
  • 49:52 --> 49:55other the other thing that keeps
  • 49:55 --> 49:58coming that I keep thinking about is.
  • 49:58 --> 50:00This idea of the.
  • 50:00 --> 50:04Global warming and climate change are so.
  • 50:04 --> 50:07Threatening that are we wasting our time
  • 50:07 --> 50:09thinking about almost anything else?
  • 50:09 --> 50:11And there are people that make that argument.
  • 50:11 --> 50:14Jonathan Franzen had a very good piece.
  • 50:14 --> 50:16And then in The New Yorker a
  • 50:16 --> 50:18few months ago about that,
  • 50:18 --> 50:21that it's so hopeless that.
  • 50:21 --> 50:23So we we we go on as if our children our
  • 50:23 --> 50:26grandchildren are going to have decent lives.
  • 50:26 --> 50:27Whenever I was talking about
  • 50:27 --> 50:28the financial aspects of my
  • 50:28 --> 50:30generation versus your generation,
  • 50:30 --> 50:32but think about what it could be
  • 50:32 --> 50:34like for our kids and our grandkids.
  • 50:34 --> 50:36If if the world really goes to
  • 50:36 --> 50:38hell in the way it seems to be in
  • 50:38 --> 50:41a lot of people think it will be
  • 50:41 --> 50:42because of reinforcing.
  • 50:42 --> 50:45Feedbacks that are just getting worse and
  • 50:45 --> 50:47worse and nobody is doing anything about
  • 50:47 --> 50:50it at any kind of scale that it could.
  • 50:50 --> 50:52Matter and so maybe you know you
  • 50:52 --> 50:55thinking about the brain or me talking
  • 50:55 --> 50:57about breast cancer activism for HIV,
  • 50:57 --> 50:59AIDS, or even trying to illuminate.
  • 50:59 --> 51:00And it's horrible.
  • 51:00 --> 51:02Probably you know, tuberculosis or HIV,
  • 51:02 --> 51:05aids and all these other terrible
  • 51:05 --> 51:06global health problems.
  • 51:06 --> 51:08But all that could be meaningless
  • 51:08 --> 51:11in a big hurry if if climate change
  • 51:11 --> 51:13gets so bad that there's no food
  • 51:13 --> 51:16and there's a lack of water and all
  • 51:16 --> 51:20that, well, so so this is again an area that.
  • 51:20 --> 51:22You know you see the science, right?
  • 51:22 --> 51:25The science is fairly clear and robust.
  • 51:25 --> 51:27I mean, there are these models
  • 51:27 --> 51:29that have been known for decades,
  • 51:29 --> 51:30and there are advocacy groups
  • 51:30 --> 51:32like there's a movement.
  • 51:32 --> 51:34You know that it's getting
  • 51:34 --> 51:35more popular with young
  • 51:35 --> 51:38people, which is good. Which is good. But
  • 51:38 --> 51:40so, like when, how do you
  • 51:40 --> 51:42view a critical mass forming?
  • 51:42 --> 51:44So at what point? I don't know. This
  • 51:44 --> 51:47is not something that I've been involved in.
  • 51:47 --> 51:51Sometimes I feel like I should be.
  • 51:51 --> 51:53You know involved in it and you
  • 51:53 --> 51:55see things like Jane Fonda getting
  • 51:55 --> 51:57arrested every Friday along with
  • 51:57 --> 51:59a bunch of other celebrities.
  • 51:59 --> 52:02Now on the steps of the Capitol.
  • 52:02 --> 52:04Maybe that will call attention to it,
  • 52:04 --> 52:07but it's very hard to wrap your
  • 52:07 --> 52:09head around how bad it is an
  • 52:09 --> 52:11particularly because you've got just
  • 52:11 --> 52:14become a religion to be against it.
  • 52:14 --> 52:15For certain political parties.
  • 52:15 --> 52:17So people are much more.
  • 52:19 --> 52:21Aligned to disbelieve it even,
  • 52:21 --> 52:23even though the evidence is stronger.
  • 52:23 --> 52:25And also it's happening over a time
  • 52:25 --> 52:27frame that we don't quite understand.
  • 52:27 --> 52:30Have a new treatment for cystic
  • 52:30 --> 52:31fibrosis or cancer comes along.
  • 52:31 --> 52:33Yeah yesterday it wasn't here today
  • 52:33 --> 52:36is here and we suddenly see it.
  • 52:36 --> 52:37This is given
  • 52:37 --> 52:40to patients better and in some way. But this
  • 52:40 --> 52:44doesn't work that way. Anne.
  • 52:44 --> 52:46It could be just awful an I I don't
  • 52:46 --> 52:48know if there are people here an
  • 52:48 --> 52:50elsewhere here yell and elsewhere who
  • 52:50 --> 52:53work at the idea of communicating this.
  • 52:53 --> 52:55You know, how do you tell people
  • 52:55 --> 52:57this is such a serious problem
  • 52:57 --> 52:59that we have to worry about it?
  • 52:59 --> 53:01I remember even a few one of
  • 53:01 --> 53:03the few times we were talking
  • 53:03 --> 53:05bout good reactions to stories.
  • 53:05 --> 53:07I did it with the one time
  • 53:07 --> 53:09I got a lot of hate Mail.
  • 53:09 --> 53:12And in those days it was just Mail.
  • 53:12 --> 53:13It was an email or social
  • 53:13 --> 53:16media when I did a story about.
  • 53:16 --> 53:16Global warming,
  • 53:16 --> 53:18one of the first stories when
  • 53:18 --> 53:20I was starting to become more
  • 53:20 --> 53:22public issue what year is that?
  • 53:22 --> 53:24Oh, is in the 80s eighties.
  • 53:24 --> 53:26Brian Johansson came out and but
  • 53:26 --> 53:28it didn't phase and people can't.
  • 53:28 --> 53:29You know, then,
  • 53:29 --> 53:31when it's really hot on the East
  • 53:31 --> 53:33Coast and everybody in Washington,
  • 53:33 --> 53:34New York's miserable and or
  • 53:34 --> 53:36there's a power outage.
  • 53:36 --> 53:37Or there's a big hurricane.
  • 53:37 --> 53:39Now people are starting to
  • 53:39 --> 53:40accept the severe weather.
  • 53:40 --> 53:43Is is part of global climate change and
  • 53:43 --> 53:45that wasn't accepted for a long time.
  • 53:45 --> 53:47Well, so so this is.
  • 53:47 --> 53:50One of my editors at Scientific
  • 53:50 --> 53:51American, Mike Lemonick,
  • 53:51 --> 53:54who had interviewed for this podcast.
  • 53:54 --> 53:56He and I had a discussion
  • 53:56 --> 53:58about the impact of science
  • 53:58 --> 54:00journalism on science policy,
  • 54:00 --> 54:03and so I'm curious if you feel
  • 54:03 --> 54:05like your journalism in AIDS and
  • 54:05 --> 54:07cancer treatments and you covered
  • 54:07 --> 54:10Alzheimer's and Human Genome project,
  • 54:10 --> 54:13do you feel like that has had an
  • 54:13 --> 54:16affect in sculpting policy? I
  • 54:16 --> 54:17think not mine necessarily,
  • 54:17 --> 54:19but overall it does.
  • 54:19 --> 54:21I think that awareness does
  • 54:21 --> 54:22help people appreciate where
  • 54:22 --> 54:24their tax dollars are going,
  • 54:24 --> 54:28but there and that's been part of perhaps
  • 54:28 --> 54:31the reason that there was not a lot of.
  • 54:31 --> 54:33Objection to it science is
  • 54:33 --> 54:34always done pretty well.
  • 54:34 --> 54:37I'd get has its ups and downs
  • 54:37 --> 54:39and you mentioned before the
  • 54:39 --> 54:41when the NIH doubled its budget,
  • 54:41 --> 54:43which was a huge mistake that
  • 54:43 --> 54:46was made during the Clinton Bill
  • 54:46 --> 54:47Clinton administration, the.
  • 54:49 --> 54:51They doubled the budget,
  • 54:51 --> 54:53but then they didn't fall through,
  • 54:53 --> 54:55so there's all these graduate students
  • 54:55 --> 54:57and postdocs who suddenly given fell
  • 54:57 --> 55:00off a Cliff like doubling the
  • 55:00 --> 55:01enrollment in medical school without
  • 55:01 --> 55:03doubling residency right exactly.
  • 55:03 --> 55:06Yeah, it was a bad idea, yeah?
  • 55:06 --> 55:08But then again, there's a big tendency to.
  • 55:08 --> 55:11If somebody puts money on the
  • 55:11 --> 55:13table to take it and not say
  • 55:13 --> 55:15we're not going to take that.
  • 55:15 --> 55:18But but those stories are satisfying.
  • 55:18 --> 55:19I enjoy reading about.
  • 55:19 --> 55:22Science or and I enjoy just like I
  • 55:22 --> 55:25enjoy a good play or a movie that
  • 55:25 --> 55:27has nothing to do with science.
  • 55:27 --> 55:29It's part of the human experience
  • 55:29 --> 55:32and I think that it makes people feel
  • 55:32 --> 55:34satisfied to get good information.
  • 55:34 --> 55:35Well, you certainly made
  • 55:35 --> 55:37thousands of millions of people satisfied.
  • 55:37 --> 55:40Flickering through the years and I guess
  • 55:40 --> 55:43we're actually running a little low on time.
  • 55:43 --> 55:45I don't want you to be late
  • 55:45 --> 55:48for your new class, OK?
  • 55:48 --> 55:51But we are OK. We are we OK?
  • 55:51 --> 55:54Yeah, I think we have 5 minutes 5 minutes.
  • 55:54 --> 55:56OK, I use magic that out about time,
  • 55:56 --> 55:59but you know, just in the last
  • 55:59 --> 56:01five minutes here I'm like what?
  • 56:01 --> 56:02Where do you see science
  • 56:02 --> 56:04journalism an going in the future?
  • 56:04 --> 56:07I because I have this sense that science
  • 56:07 --> 56:09is becoming more and more complex and
  • 56:09 --> 56:11to be able to report about science,
  • 56:11 --> 56:13you're going to have to become
  • 56:13 --> 56:14more and more sophisticated.
  • 56:14 --> 56:16Like for example, you you had a,
  • 56:16 --> 56:20you know, a whole leg and not just a shoe.
  • 56:20 --> 56:22Because you had a lot of scientific
  • 56:22 --> 56:25training and so that gave you a springboard
  • 56:25 --> 56:27into the world of science journalism.
  • 56:27 --> 56:30So how do you feel the next generation
  • 56:30 --> 56:32of science journalists are going
  • 56:32 --> 56:34to feel very optimistic about it?
  • 56:34 --> 56:36Because like the stuff that you do in
  • 56:36 --> 56:39Scientific American and all the good
  • 56:39 --> 56:41stuff that's in National Geographic sites,
  • 56:41 --> 56:43and there, there is an enormous
  • 56:43 --> 56:45amount of good information out there.
  • 56:45 --> 56:47And there are certain percentage
  • 56:47 --> 56:48of people who seek it.
  • 56:48 --> 56:51The big problems are that a lot of
  • 56:51 --> 56:53stuff gets trivialized, particularly.
  • 56:53 --> 56:54Nutritional Epidemiology, you know,
  • 56:54 --> 56:56I can promise you that they'll in
  • 56:56 --> 56:58February there will be stories
  • 56:58 --> 56:59that just before Valentine's Day
  • 56:59 --> 57:01that chocolate is good for you.
  • 57:03 --> 57:05Yeah this and wanted by Hershey.
  • 57:05 --> 57:07Sponsored by you know somebody will
  • 57:07 --> 57:09do is to study of 17 people and find
  • 57:09 --> 57:12out that there's an antioxidant.
  • 57:12 --> 57:15Chocolate of course you have to eat so
  • 57:15 --> 57:19much of the chocolate you gain 10 pounds.
  • 57:19 --> 57:23But the and those things are constant.
  • 57:27 --> 57:28Uh, with evergreens,
  • 57:28 --> 57:30they think they're constantly showing
  • 57:30 --> 57:33up on the morning talk shows like
  • 57:33 --> 57:35the Today Show and Good Morning
  • 57:35 --> 57:37America and the CBS Morning show.
  • 57:37 --> 57:40The people are all whole another.
  • 57:40 --> 57:44John Oliver did a great spot on this on.
  • 57:44 --> 57:48John Oliver did a very good spot
  • 57:48 --> 57:51about science, journalism and.
  • 57:51 --> 57:53It in the whole lot of stuff
  • 57:53 --> 57:55gets blown on it, blown up.
  • 57:55 --> 57:57Out of proportion.
  • 57:57 --> 58:00And it's not just.
  • 58:00 --> 58:02These small studies get a lot
  • 58:02 --> 58:04of attention because they come
  • 58:04 --> 58:06to a result that people want
  • 58:06 --> 58:08to hear or it scares people or
  • 58:08 --> 58:09whatever it takes to.
  • 58:09 --> 58:10I love the wine study.
  • 58:10 --> 58:12Yeah, one drink two to three
  • 58:12 --> 58:14glasses of wine. Your heart.
  • 58:14 --> 58:15Well yeah, right and under the
  • 58:15 --> 58:17guise Sinclair it at Harvard,
  • 58:17 --> 58:18David Sinclair has been fortunate
  • 58:18 --> 58:20company to try supposedly distills
  • 58:20 --> 58:22the antioxidant from red wine into a
  • 58:22 --> 58:24pill that prevents you from aging.
  • 58:24 --> 58:26So why would you ever want to take the
  • 58:26 --> 58:29pill? And you can just drink the wine?
  • 58:29 --> 58:31Yeah, exactly exactly. You have to drink.
  • 58:31 --> 58:33Case of it together, but alright here.
  • 58:33 --> 58:36Let's say in an afternoon. But
  • 58:36 --> 58:39but the as I clear that that's going to work.
  • 58:39 --> 58:42The problem is that that part of the
  • 58:42 --> 58:45scientific process is not as getting better.
  • 58:45 --> 58:47Major publications like the New
  • 58:47 --> 58:48York Times and Washington Post,
  • 58:48 --> 58:50and I think to a certain extent
  • 58:50 --> 58:52the networks in their coverage
  • 58:52 --> 58:54have done less of that dude.
  • 58:54 --> 58:56Taking small studies and they can
  • 58:56 --> 58:59go for a whole lot of reasons,
  • 58:59 --> 59:01go either way and making
  • 59:01 --> 59:03a big deal out of it.
  • 59:05 --> 59:08But there is a lot of lack of
  • 59:08 --> 59:09understanding of the need for.
  • 59:11 --> 59:14This consistent beta the data coming to
  • 59:14 --> 59:16the same conclusion before you make it
  • 59:16 --> 59:18recommendation and a lot of things changed.
  • 59:18 --> 59:20I mean it was a really big deal in the
  • 59:20 --> 59:231990s when the Women's Health Initiative
  • 59:23 --> 59:25showed that hormone replacement
  • 59:25 --> 59:27therapy was not was more harmful than
  • 59:27 --> 59:29beneficial and millions of women
  • 59:29 --> 59:31there went off it in an afternoon and
  • 59:31 --> 59:33suffered severe consequences like hot
  • 59:33 --> 59:35flashes and feeling really terrible.
  • 59:35 --> 59:37But there have been all these small
  • 59:37 --> 59:40studies and when I was guilty of doing,
  • 59:40 --> 59:42going along with some of these
  • 59:42 --> 59:43small studies that said.
  • 59:43 --> 59:46It enhanced your memory at made,
  • 59:46 --> 59:48made a woman's skin better and
  • 59:48 --> 59:50all kinds of stuff.
  • 59:50 --> 59:52And it turned out it when somebody actually
  • 59:52 --> 59:55did the giant randomized control trial.
  • 59:55 --> 59:56It wasn't the case.
  • 59:56 --> 59:59Well, maybe then part of the you know,
  • 59:59 --> 60:01science. Education that science
  • 60:01 --> 60:03journalists give should be more
  • 60:03 --> 60:05focused on the process of science.
  • 60:05 --> 60:06Rather, the process of
  • 60:06 --> 60:08science before you knowing the
  • 60:08 --> 60:10process of science before you report
  • 60:10 --> 60:13it is very important and that there
  • 60:13 --> 60:14are organizations like Annenberg
  • 60:14 --> 60:17Foundation supports a lot of of
  • 60:17 --> 60:18it's called there's a journalist.
  • 60:18 --> 60:21Tip Sheet is not just about science,
  • 60:21 --> 60:23but it tells you how to.
  • 60:23 --> 60:25How to approach this subject and
  • 60:25 --> 60:28to think about it and frame it.
  • 60:28 --> 60:31And you might want to talk to.
  • 60:31 --> 60:32Look at these resources and there is
  • 60:32 --> 60:35the AAA S the American associated with
  • 60:35 --> 60:37advancement of science has a whole
  • 60:37 --> 60:39lot of resources for journalists,
  • 60:39 --> 60:41so because a lot of mainstream publications
  • 60:41 --> 60:43have cut back on their science reporting,
  • 60:43 --> 60:46so you don't have people who do it day
  • 60:46 --> 60:49in and day out who know the process.
  • 60:49 --> 60:51So that's why you get the
  • 60:51 --> 60:52somebody from USA TODAY.
  • 60:52 --> 60:53Calling somebody out, asking stupid
  • 60:53 --> 60:55questions because they they don't have.
  • 60:55 --> 60:57They don't have background.
  • 60:57 --> 60:59They used to have a lot.
  • 60:59 --> 61:00USA TODAY as an example.
  • 61:00 --> 61:03They used to have a big size step.
  • 61:03 --> 61:08And if they laid off almost all an.
  • 61:08 --> 61:11So there, but for people who want
  • 61:11 --> 61:13good information is out there.
  • 61:13 --> 61:17I think that there's not a danger that.
  • 61:17 --> 61:20An when things happen that scare
  • 61:20 --> 61:22public health people enough,
  • 61:22 --> 61:24the.
  • 61:24 --> 61:25Like vaccine hesitancy,
  • 61:25 --> 61:27there is a growing movement to
  • 61:27 --> 61:29handle it correctly.
  • 61:29 --> 61:30It hasn't worked with edit
  • 61:30 --> 61:32global warming yet,
  • 61:32 --> 61:34but I think is young people get
  • 61:34 --> 61:36more interested in adults.
  • 61:36 --> 61:38It is more of a defining
  • 61:38 --> 61:40issue than they have when I
  • 61:40 --> 61:42certainly hope so, especially
  • 61:42 --> 61:43for creating great grandchildren.
  • 61:43 --> 61:45I don't think it's going
  • 61:45 --> 61:47to be great. I think as
  • 61:47 --> 61:48we grandchildren,
  • 61:48 --> 61:50grandchildren they're going to
  • 61:50 --> 61:53really have to look at these.
  • 61:53 --> 61:55120 degree Fahrenheit days.
  • 61:55 --> 61:57There are occurring out regularly in
  • 61:57 --> 62:00Bombay and these water tables going
  • 62:00 --> 62:02down all over the world and crop
  • 62:02 --> 62:04shifting and things like Dengue a
  • 62:04 --> 62:07moving North in a big hurry because
  • 62:07 --> 62:10of mosquitoes are moving or it's
  • 62:10 --> 62:12those are all that matters and well,
  • 62:12 --> 62:14maybe we should be re channel
  • 62:14 --> 62:17their energy into global warming.
  • 62:17 --> 62:19May be very helpful thing.
  • 62:19 --> 62:21Well thank you so much for coming.
  • 62:21 --> 62:24Yeah, I've really enjoyed speaking with
  • 62:35 --> 62:36Hope you enjoyed that episode.
  • 62:36 --> 62:39Thanks again to Bob for being on the podcast.
  • 62:39 --> 62:42You can find Bob on Twitter at Robert
  • 62:42 --> 62:44Buzzell and that's at Robert Bazell.
  • 62:44 --> 62:47You can also find him at his adjunct
  • 62:47 --> 62:48faculty profile page at yale.edu.
  • 62:48 --> 62:51You could also purchase this book her too,
  • 62:51 --> 62:52at your favorite bookseller.
  • 62:52 --> 62:55Pretty sure I picked up a copy on
  • 62:55 --> 62:57Amazon.com and it arrived in two days.
  • 62:57 --> 62:58It was awesome.
  • 62:58 --> 63:00Thanks to the Yale School of
  • 63:00 --> 63:02Medicine for sponsoring the podcast,
  • 63:02 --> 63:04and especially to Adrian Bottom
  • 63:04 --> 63:06Burger for producing this podcast
  • 63:06 --> 63:08and Ryan McEvoy for sound editing.
  • 63:08 --> 63:10Special thanks to you for listening again.
  • 63:10 --> 63:11My name is Daniel Barron
  • 63:11 --> 63:13and I've been your host.
  • 63:13 --> 63:16An will see you next time on science at all.