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Melanoma and Skin Cancer Awareness 2022

Transcript

  • 00:00 --> 00:02Funding for Yale Cancer Answers is
  • 00:02 --> 00:04provided by Smilow Cancer Hospital.
  • 00:06 --> 00:08Welcome to Yale Cancer Answers with
  • 00:08 --> 00:10your host, doctor Anees Chagpar.
  • 00:10 --> 00:12Yale Cancer Answers features the
  • 00:12 --> 00:15latest information on cancer care by
  • 00:15 --> 00:16welcoming oncologists and specialists
  • 00:16 --> 00:18who are on the forefront of the
  • 00:18 --> 00:20battle to fight cancer. This week,
  • 00:20 --> 00:21it's a conversation about the
  • 00:21 --> 00:23care of patients with Melanoma
  • 00:23 --> 00:24with Doctor Jonathan Leventhal.
  • 00:24 --> 00:27Dr Leventhal is an assistant professor
  • 00:27 --> 00:29of dermatology at the Yale School
  • 00:29 --> 00:31of Medicine where Doctor Chagpar is
  • 00:31 --> 00:33a professor of surgical oncology.
  • 00:35 --> 00:37So Jonathan, maybe we can start off
  • 00:37 --> 00:40by you telling us a little bit more
  • 00:40 --> 00:41about yourself and what it is you do.
  • 00:42 --> 00:45I'm Jonathan Leventhal and I direct the
  • 00:45 --> 00:46oncodermatology clinic.
  • 00:46 --> 00:49So in this clinic I take care of
  • 00:49 --> 00:51patients who develop all types of skin,
  • 00:51 --> 00:53hair and nail problems from
  • 00:53 --> 00:55all types of cancer treatment.
  • 00:55 --> 00:56And I also perform skin checks for patients
  • 00:56 --> 00:58who have a history of skin cancer.
  • 00:59 --> 01:02So you know now that we're
  • 01:02 --> 01:04emerging from the pandemic
  • 01:04 --> 01:07and the weather is starting to get nicer,
  • 01:07 --> 01:09many people start thinking
  • 01:09 --> 01:11more about skin cancers,
  • 01:11 --> 01:12so can you kind of give
  • 01:12 --> 01:14us the lay of the land?
  • 01:14 --> 01:16How common is skin cancer?
  • 01:16 --> 01:18What are the different types and
  • 01:18 --> 01:22what should people be aware of?
  • 01:22 --> 01:24So skin cancer is actually the most
  • 01:24 --> 01:26common type of cancer, just in general,
  • 01:26 --> 01:28so there's three main types.
  • 01:28 --> 01:30Basal cell, which is by far
  • 01:30 --> 01:32the most common of all of them,
  • 01:32 --> 01:35followed by squamous cell and then Melanoma,
  • 01:35 --> 01:37which is only about 1% of skin cancers
  • 01:37 --> 01:40but is the deadliest and so basal
  • 01:41 --> 01:43cells can happen and up to 30% of
  • 01:43 --> 01:45white individuals in their lifetime.
  • 01:45 --> 01:47So it is so common it usually
  • 01:47 --> 01:50presents in sun exposed areas,
  • 01:50 --> 01:51often like a little pimple that
  • 01:51 --> 01:53just doesn't seem to heal it.
  • 01:53 --> 01:55Maybe a little sore or it can
  • 01:55 --> 01:57bleed and it just persists.
  • 01:57 --> 01:59Then there's squamous cells which are
  • 01:59 --> 02:01the second most common type and these
  • 02:01 --> 02:03also occur in areas of sun damage
  • 02:03 --> 02:05and they usually present almost like
  • 02:05 --> 02:09a painful wardy bump on the skin and
  • 02:09 --> 02:11then finally Melanoma as I mentioned
  • 02:12 --> 02:14which is the least carbon of the three.
  • 02:14 --> 02:16But that's about a let's say an
  • 02:16 --> 02:18incidence of about affecting one in 40
  • 02:18 --> 02:20individuals in their lifetime that often
  • 02:20 --> 02:23looks like an atypical appearing mall.
  • 02:23 --> 02:24It's usually a pigmented lesion.
  • 02:25 --> 02:27So you know, that's one thing
  • 02:27 --> 02:30that I think a lot of people may
  • 02:30 --> 02:32not be aware of is that some
  • 02:32 --> 02:34skin cancers are not pigmented.
  • 02:34 --> 02:37I think that so often people think about
  • 02:37 --> 02:40skin cancer and they think Melanoma.
  • 02:40 --> 02:41And when we think Melanoma,
  • 02:41 --> 02:43we think of a pigmented lesion.
  • 02:43 --> 02:45But basal cells and
  • 02:45 --> 02:46squamous cells aren't right.
  • 02:47 --> 02:48Yes, that is correct.
  • 02:48 --> 02:50So basal cells, they often look pink
  • 02:50 --> 02:53and pearly almost like a pimple and and
  • 02:53 --> 02:55the same is true of squamous cells.
  • 02:55 --> 02:58They're often pink in color and
  • 02:58 --> 03:00wardian texture, so they don't
  • 03:00 --> 03:02look like the classic Melanoma,
  • 03:02 --> 03:04which is like an atypical looking dark
  • 03:04 --> 03:08brown or black lesion which is asymmetrical,
  • 03:08 --> 03:09and so I think it's really
  • 03:09 --> 03:11important to know those differences
  • 03:12 --> 03:15and so how can people tell the difference
  • 03:15 --> 03:17between what could be a normal pimple
  • 03:17 --> 03:19and what could be a basal cell?
  • 03:20 --> 03:22Yeah, so normal pimples fortunately heal
  • 03:22 --> 03:26and they self resolve within a matter of.
  • 03:26 --> 03:27Weeks, whereas basal cells often
  • 03:27 --> 03:30start as a small lesion and then it
  • 03:30 --> 03:32becomes larger and it persists over
  • 03:32 --> 03:34the course of months and months,
  • 03:34 --> 03:38and so that's really the main way.
  • 03:38 --> 03:40I always tell my patients if there's
  • 03:40 --> 03:42something on your skin that just doesn't
  • 03:42 --> 03:44seem right, doesn't heal, persists,
  • 03:44 --> 03:47or is painful definitely, you know,
  • 03:47 --> 03:49tell me or tell your dermatologist
  • 03:50 --> 03:52and so the other thing that you
  • 03:52 --> 03:54mentioned is that basal cells happen
  • 03:54 --> 03:57in about 30% of white patients.
  • 03:57 --> 03:59And so when we think about
  • 03:59 --> 04:00skin cancers in general,
  • 04:00 --> 04:03is it true that these occur
  • 04:03 --> 04:04primarily in white patients?
  • 04:04 --> 04:09And do people who are of other races or
  • 04:09 --> 04:11ethnicities get skin cancers as well?
  • 04:12 --> 04:14That's a really great question,
  • 04:14 --> 04:16and so the short answer is, yes.
  • 04:16 --> 04:18Anybody can develop skin cancer.
  • 04:18 --> 04:21It is true that these skin cancers,
  • 04:21 --> 04:24basal cell squamous cells and
  • 04:24 --> 04:26melanomas particularly occur in white
  • 04:26 --> 04:28individuals who have had a lot of sun.
  • 04:28 --> 04:31Damage, but we have seen all these types
  • 04:31 --> 04:33of skin cancers in various ethnicities.
  • 04:33 --> 04:34So interestingly, Melanoma,
  • 04:34 --> 04:36which is in really important one
  • 04:36 --> 04:39to talk about when it does happen
  • 04:39 --> 04:41in patients who have skin of color.
  • 04:41 --> 04:43It can occur in areas that we might
  • 04:43 --> 04:44not think about for skin cancer,
  • 04:44 --> 04:47so that includes on the palms and the soles,
  • 04:47 --> 04:49or even under the toenails.
  • 04:49 --> 04:51And so there seems to be some
  • 04:51 --> 04:53sort of predisposition for that
  • 04:53 --> 04:55with Melanoma and so definitely
  • 04:55 --> 04:57important to know about and even
  • 04:57 --> 04:59with basal cells and squamous cells.
  • 04:59 --> 05:02I have plenty of patients who are
  • 05:02 --> 05:04Hispanic or African American and and
  • 05:04 --> 05:07they develop these skin cancers so it
  • 05:07 --> 05:09doesn't only happen in white individuals.
  • 05:09 --> 05:11Skin cancer can affect everyone.
  • 05:12 --> 05:15When you think about skin
  • 05:15 --> 05:17cancer occurring under toenails,
  • 05:17 --> 05:18we've often heard about that.
  • 05:18 --> 05:21But when we look at pictures,
  • 05:21 --> 05:25so if anybody Googles.
  • 05:25 --> 05:27You know Melanoma and looks at pictures
  • 05:27 --> 05:30of of these occurring under the toenail.
  • 05:30 --> 05:31It kind of looks like
  • 05:31 --> 05:32somebody stubbed their toe.
  • 05:32 --> 05:34It looks like they may have a bit
  • 05:34 --> 05:36of a hematoma under their toenail.
  • 05:36 --> 05:40How can you tell the difference between?
  • 05:40 --> 05:41Stubbing your toe and getting
  • 05:41 --> 05:44a a hematoma under a toenail.
  • 05:44 --> 05:46Versus, you know a Melanoma that you
  • 05:46 --> 05:49might need to be more concerned about.
  • 05:49 --> 05:51Yet another really good point.
  • 05:51 --> 05:53And so when dermatologist examined patients,
  • 05:53 --> 05:55what we look for regarding the
  • 05:55 --> 05:58fingers and the toes is a dark
  • 05:58 --> 05:59pigmented streak that extends from
  • 05:59 --> 06:02the nail fold up throughout the nail,
  • 06:02 --> 06:04and so that's called melana nikkia.
  • 06:04 --> 06:07So many Kate. Many times Melanoma
  • 06:07 --> 06:10actually begins as kind of a.
  • 06:10 --> 06:11Line and Nikki a streak.
  • 06:11 --> 06:13A dark band under your nail,
  • 06:13 --> 06:15and so if you see any new dark
  • 06:15 --> 06:18bands under your nails that are
  • 06:18 --> 06:21different than maybe some other
  • 06:21 --> 06:23nails findings that you have,
  • 06:23 --> 06:26you should definitely see the dermatologist.
  • 06:26 --> 06:29Now regarding the question about trauma.
  • 06:29 --> 06:30Fortunately only those really
  • 06:30 --> 06:33advanced cases of Melanoma under
  • 06:33 --> 06:35the nail bed really look like the
  • 06:35 --> 06:38whole nails coming up and bleeding
  • 06:38 --> 06:40and bloody and so those can be.
  • 06:40 --> 06:41I'm very concerning,
  • 06:41 --> 06:44so I would say if you do stub your
  • 06:44 --> 06:46toe and you have a reason for
  • 06:46 --> 06:48having a problem under your nail,
  • 06:48 --> 06:50you can be a little. You know.
  • 06:50 --> 06:51You can be reassured,
  • 06:51 --> 06:53but if you don't recall any trauma and
  • 06:53 --> 06:55now you see that your nail looks like
  • 06:55 --> 06:57it might have some bleeding underneath
  • 06:57 --> 06:59it or some dark discoloration.
  • 06:59 --> 07:02Definitely something to show your doctor
  • 07:02 --> 07:05all right so we know what to
  • 07:05 --> 07:08kind of look for in terms of
  • 07:08 --> 07:10basal cells and melanomas.
  • 07:10 --> 07:11Squamous cells you mentioned?
  • 07:11 --> 07:13They kind of look a little
  • 07:13 --> 07:15bit more scaly, right?
  • 07:15 --> 07:18Yes? Squamous cells can appear sometimes.
  • 07:18 --> 07:19Similar to basal cells
  • 07:19 --> 07:22they can be pink and scaly.
  • 07:22 --> 07:24They can sometimes have a warty
  • 07:24 --> 07:26texture and one thing that I find
  • 07:26 --> 07:27is helpful with squamous cells,
  • 07:27 --> 07:29as these tend to be painful.
  • 07:29 --> 07:31And so if you have a lesion on
  • 07:31 --> 07:32your skin when you touch it,
  • 07:32 --> 07:33it's painful.
  • 07:33 --> 07:35That's something that you should
  • 07:35 --> 07:36definitely tell your doctor
  • 07:36 --> 07:38dermatologist about because many times
  • 07:38 --> 07:41that's how these squamous cells present.
  • 07:41 --> 07:43It can also grow very rapidly,
  • 07:43 --> 07:46usually a lot faster than a basal cell.
  • 07:46 --> 07:49Let's suppose you have one of these
  • 07:49 --> 07:52lesions you've listened to this show,
  • 07:52 --> 07:54and you've discovered that you might
  • 07:54 --> 07:58have one of these and you go and you see
  • 07:58 --> 08:00your family doctor or your dermatologist.
  • 08:00 --> 08:02What's generally the next step in
  • 08:02 --> 08:04terms of making that diagnosis,
  • 08:04 --> 08:06and how bad is the treatment?
  • 08:08 --> 08:11So once there's a suspicious skin lesion,
  • 08:11 --> 08:13the way that we diagnose the condition
  • 08:13 --> 08:15is we perform a skin biopsy,
  • 08:15 --> 08:16so this is a really simple procedure
  • 08:16 --> 08:18that takes place in the office.
  • 08:18 --> 08:21It only takes a few minutes to do locally.
  • 08:21 --> 08:22The area is numbed up with
  • 08:22 --> 08:24a little bit of lidocaine,
  • 08:24 --> 08:26and then the area is either shaved
  • 08:26 --> 08:29off or we use something called a
  • 08:29 --> 08:31punch biopsy and we're able to get
  • 08:31 --> 08:33the lesion into a bottle that was
  • 08:33 --> 08:35sent to a pathologist who then
  • 08:35 --> 08:37looks under the microscope and is
  • 08:37 --> 08:38able to give us an answer.
  • 08:39 --> 08:41Well, that's great for lesions
  • 08:41 --> 08:43that are on the skin, but if
  • 08:43 --> 08:45you've got one of those melanomas
  • 08:45 --> 08:48that's on a toenail under the nail,
  • 08:48 --> 08:50how do you do a biopsy of that?
  • 08:50 --> 08:52Yeah, so those are a little
  • 08:52 --> 08:53bit more complicated.
  • 08:53 --> 08:55And so what's really important
  • 08:55 --> 08:57about biopsying those lesions is
  • 08:57 --> 08:59that a specialist who's familiar
  • 08:59 --> 09:01with doing it performs it,
  • 09:01 --> 09:02and so, for instance,
  • 09:02 --> 09:04if we want to biopsy the nail,
  • 09:04 --> 09:06and in particular we want to biopsy
  • 09:06 --> 09:08what's called the nail matrix,
  • 09:08 --> 09:09which is where.
  • 09:09 --> 09:12Most of these cells, Melanoma cells form,
  • 09:12 --> 09:15and then they expand upward into the nail.
  • 09:15 --> 09:18We sometimes have to after we numb it up,
  • 09:18 --> 09:20actually peel back some of the skin and
  • 09:20 --> 09:23even remove the nail plate itself sometimes,
  • 09:23 --> 09:25and so those procedures can be
  • 09:25 --> 09:27a little bit more complicated.
  • 09:28 --> 09:31Yeah, doesn't sound like fun.
  • 09:31 --> 09:34OK, so so let's suppose a
  • 09:34 --> 09:37diagnosis is made of a skin cancer.
  • 09:37 --> 09:40Now you mentioned at the top of
  • 09:40 --> 09:42the show that these are cells
  • 09:42 --> 09:44and squamous cells are incredibly
  • 09:44 --> 09:46common but not very lethal.
  • 09:46 --> 09:48Unlike Melanoma, little less
  • 09:48 --> 09:52common but far more lethal, so.
  • 09:52 --> 09:54Does the treatment vary between these
  • 09:54 --> 09:57different kinds of cancers as well?
  • 09:57 --> 09:59Yeah, so. Fortunately,
  • 09:59 --> 10:02in most cases of basal cell,
  • 10:02 --> 10:04squamous cell, and even Melanoma,
  • 10:04 --> 10:07these skin cancers are found relatively
  • 10:07 --> 10:10early and very easily treated and cured,
  • 10:10 --> 10:12and so the treatment for basal cells
  • 10:12 --> 10:14and squamous cells which we can kind
  • 10:14 --> 10:16of lump together is with surgical
  • 10:16 --> 10:19removal and so usually a simple
  • 10:19 --> 10:21excision is performed for these.
  • 10:21 --> 10:23If they happen to occur on a more
  • 10:23 --> 10:25sensitive area like let's say the face or
  • 10:25 --> 10:27the hands of the feet or the genitals,
  • 10:27 --> 10:30then they'll be removed by a technique.
  • 10:30 --> 10:33Which is called Mohs surgery and this is
  • 10:33 --> 10:36basically very similar to a simple excision.
  • 10:37 --> 10:40It's just that a little bit of the skin
  • 10:40 --> 10:42cancer is removed by a shave at a time,
  • 10:42 --> 10:44and then the patient waits while the
  • 10:44 --> 10:45doctor looks under the microscope
  • 10:45 --> 10:47to make sure they got it all.
  • 10:47 --> 10:49If there happens to be an area
  • 10:49 --> 10:50that's remaining,
  • 10:50 --> 10:52then the doctor will go back to
  • 10:52 --> 10:54perform additional shave removal of it.
  • 10:54 --> 10:58Now melanomas are removed as well by surgery.
  • 10:58 --> 10:59However,
  • 10:59 --> 11:01the procedures usually a little bit more.
  • 11:01 --> 11:03Tailed because the margins are
  • 11:03 --> 11:04a little bit greater,
  • 11:04 --> 11:06meaning the area around the skin
  • 11:06 --> 11:08cancer is greater to ensure that
  • 11:08 --> 11:10there no cells left behind and if
  • 11:10 --> 11:12the Melanoma was a little bit thicker
  • 11:12 --> 11:14then actually a lymph node is obtained
  • 11:14 --> 11:17at the same time of the excision,
  • 11:17 --> 11:19and that's called the Sentinel
  • 11:19 --> 11:20lymph node removal,
  • 11:20 --> 11:21and that's done usually by a
  • 11:21 --> 11:23general or a plastic surgeon.
  • 11:24 --> 11:26So now wait a minute when you were
  • 11:26 --> 11:28talking about the basal cells and
  • 11:28 --> 11:29the squamous cells and you were
  • 11:29 --> 11:31talking about more sensitive areas.
  • 11:31 --> 11:33You mentioned that these
  • 11:33 --> 11:34could happen on the genitals,
  • 11:34 --> 11:36so some of our listeners might
  • 11:36 --> 11:38be very curious about that.
  • 11:38 --> 11:40Thinking. How does somebody get a
  • 11:40 --> 11:43cancer in that part of the skin?
  • 11:43 --> 11:45We thought that most skin cancers
  • 11:45 --> 11:47are due to sun exposure.
  • 11:47 --> 11:48Was that?
  • 11:48 --> 11:50Do those occur only in people
  • 11:50 --> 11:51who go skinny dipping?
  • 11:52 --> 11:53Or what's the deal with that?
  • 11:54 --> 11:55So that's a really good question.
  • 11:56 --> 11:58So in general, yes, like any cancer,
  • 11:58 --> 11:59there's environmental and genetic
  • 11:59 --> 12:02and other components that go into it.
  • 12:02 --> 12:03O for most cases,
  • 12:03 --> 12:05they do happen in areas that are sun exposed,
  • 12:05 --> 12:08but for instance squamous cells.
  • 12:08 --> 12:10There's some risk after
  • 12:10 --> 12:12getting an HPV infection,
  • 12:12 --> 12:15and so some patients can develop genital
  • 12:15 --> 12:17lesions of squamous cell carcinoma,
  • 12:17 --> 12:20and while not and while most skin cancers
  • 12:20 --> 12:23do happen in areas that are sun exposed,
  • 12:23 --> 12:25there are for some reasons some that
  • 12:25 --> 12:27do develop in areas that have been
  • 12:27 --> 12:29protected from the sun and these might
  • 12:29 --> 12:32occur due to other genetic reasons.
  • 12:32 --> 12:34And sometimes we don't fully
  • 12:34 --> 12:35understand why these happen,
  • 12:35 --> 12:36but they can,
  • 12:36 --> 12:38so that's what makes a total body
  • 12:38 --> 12:39skin exam particularly important
  • 12:39 --> 12:42for patients who are at high risk.
  • 12:42 --> 12:42Hmm,
  • 12:42 --> 12:45interesting and so you know when you were
  • 12:45 --> 12:48talking about the squamous cell carcinomas.
  • 12:48 --> 12:51In particular, you did mention that they
  • 12:51 --> 12:55can look wartlike and so is the pathway
  • 12:55 --> 12:57to getting squamous cell carcinomas
  • 12:57 --> 13:00and genital warts similar in the
  • 13:00 --> 13:03sense that they're both caused by HPV.
  • 13:04 --> 13:06So in some ways, yes,
  • 13:06 --> 13:10but not all squamous cells are due to
  • 13:10 --> 13:13that and so with HPV viral infection,
  • 13:13 --> 13:15our body is immune.
  • 13:15 --> 13:17System is often able to help to
  • 13:17 --> 13:19help clear those infections but
  • 13:19 --> 13:21with squamous cell carcinomas.
  • 13:21 --> 13:23It's a bit more complicated because
  • 13:23 --> 13:25it can involve HPV but can also
  • 13:25 --> 13:27involve other changes in the DNA
  • 13:27 --> 13:29of the skin called mutations
  • 13:29 --> 13:30that happen from sun damage.
  • 13:32 --> 13:34Now we're going to need to take a
  • 13:34 --> 13:35short break for a medical minute,
  • 13:35 --> 13:38but please stay tuned to learn more
  • 13:38 --> 13:40about Melanoma and skin cancers with
  • 13:40 --> 13:42my guest doctor Jonathan Leventhal,
  • 13:42 --> 13:44funding for Yale Cancer Answers comes
  • 13:44 --> 13:46from Smilow Cancer Hospital where the
  • 13:46 --> 13:48bladder cancer team is at the forefront
  • 13:48 --> 13:51of bladder cancer treatment and research.
  • 13:51 --> 13:55Learn more at yalecancercenter.org.
  • 13:55 --> 13:58The American Cancer Society estimates that
  • 13:58 --> 14:01more than 65,000 Americans will be diagnosed
  • 14:01 --> 14:04with head and neck cancer this year,
  • 14:04 --> 14:07making up about 4% of all cancers
  • 14:07 --> 14:08diagnosed when detected early.
  • 14:08 --> 14:11However, head and neck cancers are
  • 14:11 --> 14:13easily treated and highly curable.
  • 14:13 --> 14:15Clinical trials are currently
  • 14:15 --> 14:17underway at federally designated
  • 14:17 --> 14:19Comprehensive cancer centers such as
  • 14:19 --> 14:21Yale Cancer Center and its Smilow
  • 14:21 --> 14:23Cancer Hospital to test innovative new
  • 14:23 --> 14:26treatments for head and neck cancers.
  • 14:26 --> 14:28Yale Cancer Center was recently
  • 14:28 --> 14:30awarded grants from the National
  • 14:30 --> 14:32Institutes of Health to fund the
  • 14:32 --> 14:35Yale Head and neck Cancer Specialized
  • 14:35 --> 14:37program of Research Excellence or
  • 14:37 --> 14:40SPORE to address critical barriers to
  • 14:40 --> 14:42treatment of head and neck squamous
  • 14:42 --> 14:45cell carcinoma due to resistance to
  • 14:45 --> 14:47immune DNA damaging and targeted therapy.
  • 14:47 --> 14:50More information is available at
  • 14:50 --> 14:52yalecancercenter.org you're listening
  • 14:52 --> 14:53to Connecticut Public Radio.
  • 14:55 --> 14:57Welcome back to Yale Cancer answers.
  • 14:57 --> 14:59This is doctor Ennist Chappar
  • 14:59 --> 15:01and I'm joined tonight by my
  • 15:01 --> 15:03guest doctor Jonathan Leventhal.
  • 15:03 --> 15:05We're here learning about the care
  • 15:05 --> 15:07of patients with melanomas and
  • 15:07 --> 15:09skin cancer in honor of Melanoma
  • 15:09 --> 15:11and skin Cancer Awareness Month.
  • 15:11 --> 15:14Now, right before the break Jonathan,
  • 15:14 --> 15:16you were mentioning that some squamous
  • 15:16 --> 15:19cell carcinoma is not all but some.
  • 15:19 --> 15:22Can occur in the genital area and
  • 15:22 --> 15:25may be related to HPV so I have
  • 15:25 --> 15:28one follow up question to that.
  • 15:28 --> 15:30Which is you know here are
  • 15:30 --> 15:31on Yale Cancer answers.
  • 15:31 --> 15:34We've talked a lot about the HPV vaccine
  • 15:34 --> 15:37and it's benefit in terms of preventing
  • 15:37 --> 15:40all kinds of different cancers,
  • 15:40 --> 15:42cervical cancer, anal cancer,
  • 15:42 --> 15:44head neck cancers.
  • 15:44 --> 15:46Does it reduce your risk of
  • 15:46 --> 15:49squamous cell carcinomas as well?
  • 15:49 --> 15:52So not in the sense of the
  • 15:52 --> 15:54squamous cell carcinomas that
  • 15:54 --> 15:56happen from ultraviolet damage,
  • 15:56 --> 15:57which is a large chunk.
  • 15:57 --> 15:59The way to prevent those is to avoid
  • 15:59 --> 16:01the sun and use sun protective measures,
  • 16:01 --> 16:02which I'm sure we'll discuss,
  • 16:02 --> 16:05but in a sense, reducing HPV related
  • 16:05 --> 16:06squamous cell carcinomas that tend
  • 16:06 --> 16:08to occur in the genitals? Yes,
  • 16:09 --> 16:11well, let's segue into how
  • 16:11 --> 16:14we can reduce our risk of.
  • 16:14 --> 16:17Ultraviolet rays and how much that
  • 16:17 --> 16:20really reduces our risk of cancer.
  • 16:20 --> 16:22So when I talk to my patients about
  • 16:22 --> 16:24protecting themselves in the sun,
  • 16:24 --> 16:26especially those that are really high risk,
  • 16:26 --> 16:28I mean obviously we have to be able to
  • 16:28 --> 16:31go outside and enjoy ourselves and so
  • 16:31 --> 16:33I think that just using a little bit
  • 16:33 --> 16:35of common sense goes a very long way.
  • 16:35 --> 16:37So first of all, when you're
  • 16:37 --> 16:39outside for a long period of time,
  • 16:39 --> 16:42wearing a hat and sunglasses is really
  • 16:42 --> 16:44easy and something that's really important.
  • 16:44 --> 16:46You know seeking shade rather
  • 16:46 --> 16:48than lying out in tanning?
  • 16:48 --> 16:50Also, something that's just an easy one,
  • 16:50 --> 16:52but if you're going to be
  • 16:52 --> 16:53outside then we have, you know,
  • 16:53 --> 16:55protective measures with sunscreen.
  • 16:55 --> 16:57And there's two main types of sunscreens.
  • 16:57 --> 16:58There's physical blockers which
  • 16:58 --> 17:00often look like those white, pasty,
  • 17:00 --> 17:02zinc, or titanium dioxide and
  • 17:02 --> 17:04those block the sun rays.
  • 17:04 --> 17:06And then there's the chemical blockers.
  • 17:06 --> 17:08Those are the ones that kind of
  • 17:08 --> 17:10rub in a little bit more nicely,
  • 17:10 --> 17:12and those basically absorb the ultraviolet
  • 17:12 --> 17:14rays before they damage the skin.
  • 17:14 --> 17:15So absolutely.
  • 17:15 --> 17:19Using sunscreen, either type with an SPF.
  • 17:19 --> 17:20That's usually, you know.
  • 17:20 --> 17:22Dermatologists like to say 30
  • 17:22 --> 17:24or higher is very protective.
  • 17:24 --> 17:26It helps prevent sunburns,
  • 17:26 --> 17:28which we know dramatically increase
  • 17:28 --> 17:31the risk of all the major skin cancers
  • 17:31 --> 17:33and and really have been shown in
  • 17:33 --> 17:35studies to reduce the risk as well.
  • 17:36 --> 17:38So let me ask you this,
  • 17:38 --> 17:40if you're going to use sunscreen,
  • 17:40 --> 17:43do you have to wear like long sleeves
  • 17:43 --> 17:45and long pants and sit in the shade?
  • 17:45 --> 17:47Or is the sunscreen sufficient
  • 17:47 --> 17:49to block the sun rays?
  • 17:50 --> 17:53So the best thing that works the best is
  • 17:53 --> 17:56obviously avoiding direct sun exposure,
  • 17:56 --> 17:58and so if you are going to be in
  • 17:58 --> 18:00the shade wearing sun protective
  • 18:00 --> 18:02clothing with long sleeve and pants,
  • 18:02 --> 18:03you know you don't need to
  • 18:03 --> 18:04have sunscreen underneath it.
  • 18:04 --> 18:06You really want to apply sunscreen
  • 18:06 --> 18:08to the areas that are uncovered,
  • 18:08 --> 18:10but most of the time people want
  • 18:10 --> 18:12to be outside and enjoy themselves,
  • 18:12 --> 18:15and you know, including myself and so for me.
  • 18:15 --> 18:17You know, putting hat sunglasses and
  • 18:17 --> 18:19sunscreen on anywhere that's exposed
  • 18:19 --> 18:21like my arms if I'm wearing AT shirt,
  • 18:21 --> 18:25my neck not forgetting my ears
  • 18:25 --> 18:26really important.
  • 18:26 --> 18:27Something else that a lot of
  • 18:27 --> 18:29my patients seem to tell me is
  • 18:29 --> 18:30that they put on sunscreen,
  • 18:30 --> 18:32but yet they still get burned.
  • 18:32 --> 18:34And so when I talk to them a little bit more,
  • 18:34 --> 18:35it turns out that maybe they
  • 18:35 --> 18:37applied it in the morning,
  • 18:37 --> 18:38but then they were playing
  • 18:38 --> 18:39basketball or tennis,
  • 18:39 --> 18:41or were out playing golf all day
  • 18:41 --> 18:42and they never reapplied it.
  • 18:42 --> 18:44So after several hours you really
  • 18:44 --> 18:46need to reapply the sunscreen,
  • 18:46 --> 18:48especially if you're going to be sweating or,
  • 18:48 --> 18:49you know,
  • 18:49 --> 18:51jumping into the pool when coming out.
  • 18:51 --> 18:53The sunscreen will not work all day long.
  • 18:53 --> 18:55How do we get the sunscreen
  • 18:55 --> 18:57underneath those nail beds?
  • 18:57 --> 19:00If Melanoma can occur under your nail, so
  • 19:00 --> 19:02that's a good question, so the nails and
  • 19:02 --> 19:05you know the fingers you know you want
  • 19:05 --> 19:07to apply sunscreen to the skin itself.
  • 19:07 --> 19:09Regarding the nail beds, those types
  • 19:09 --> 19:12of melanomas likely are not solely
  • 19:12 --> 19:15driven by the sun rays and ultraviolet.
  • 19:15 --> 19:17You know, especially in patients
  • 19:17 --> 19:18with darker skin types,
  • 19:18 --> 19:21there seems to be more of genetic
  • 19:21 --> 19:23risk factors at play there,
  • 19:23 --> 19:25and so I don't think people need to
  • 19:25 --> 19:27drive themselves a little crazy.
  • 19:27 --> 19:28By applying sunscreen under,
  • 19:28 --> 19:31you know under and around their their nails.
  • 19:31 --> 19:32I think really the focus should be
  • 19:32 --> 19:34on on exposed areas of the skin.
  • 19:35 --> 19:36Next question. We have hair
  • 19:36 --> 19:39on the top of our heads,
  • 19:39 --> 19:41some more than others,
  • 19:41 --> 19:44so if you aren't bald,
  • 19:44 --> 19:45do you still need to wear a hat?
  • 19:46 --> 19:48So the answer is yes.
  • 19:48 --> 19:51Even in patients who have a lot of hair,
  • 19:51 --> 19:54you still can find sun damage,
  • 19:54 --> 19:57precancers and skin cancers develop.
  • 19:57 --> 19:59And so the ultraviolet rays
  • 19:59 --> 20:01can still cause skin damage,
  • 20:01 --> 20:03especially in the areas of the
  • 20:03 --> 20:05midline part or in patients
  • 20:05 --> 20:07who maybe have some thinning.
  • 20:07 --> 20:09Others may be a little bit more bald.
  • 20:09 --> 20:11You can certainly get skin cancers there.
  • 20:11 --> 20:14That's actually a really common place
  • 20:14 --> 20:17for men to develop skin cancers,
  • 20:17 --> 20:21and that's on areas of thin hair scalp.
  • 20:21 --> 20:24OK, let's suppose there are some men
  • 20:24 --> 20:26who are listening who may be bold,
  • 20:26 --> 20:28but they don't particularly
  • 20:28 --> 20:30enjoy wearing a hat.
  • 20:30 --> 20:32Could they just use sunscreen on the
  • 20:32 --> 20:35top of their head instead of wearing a hat,
  • 20:35 --> 20:36just like you would on your arms
  • 20:36 --> 20:38and legs if you didn't want to
  • 20:38 --> 20:40wear long sleeves and long pants,
  • 20:41 --> 20:44sure, so hat is clearly more protective,
  • 20:44 --> 20:46but if someone does not wish to wear a hat,
  • 20:46 --> 20:48then absolutely applying sunscreen
  • 20:48 --> 20:52onto the the scalp is is very helpful.
  • 20:52 --> 20:53And you know this really
  • 20:53 --> 20:55different types of sunscreen too.
  • 20:55 --> 20:57Some lotions that seem to rub in better,
  • 20:57 --> 20:59some are creams,
  • 20:59 --> 21:01others are actually sprays.
  • 21:01 --> 21:02Which some people actually prefer
  • 21:02 --> 21:04if they have thinning on the hair,
  • 21:04 --> 21:06they just spray on some sunscreen.
  • 21:06 --> 21:08So there's really different types.
  • 21:08 --> 21:10And what I tell patients is find
  • 21:10 --> 21:12a type that works best for you.
  • 21:12 --> 21:14Don't just ask well what's the best one.
  • 21:14 --> 21:17You want a sunscreen that blocks
  • 21:17 --> 21:19both ultraviolet and ultraviolet B,
  • 21:19 --> 21:21and most of the sunscreens on the shelf.
  • 21:21 --> 21:23Do that now and you want a sunscreen
  • 21:23 --> 21:25that you actually like and use
  • 21:26 --> 21:31so the spray is a cool idea for.
  • 21:31 --> 21:33Those of us who really
  • 21:33 --> 21:34don't enjoy wearing hats.
  • 21:34 --> 21:37Could we just spray over our hair?
  • 21:37 --> 21:38Does that work?
  • 21:38 --> 21:40Would that prevent skin cancer
  • 21:40 --> 21:42and would it wreck our hair?
  • 21:44 --> 21:45So I don't wanna be blamed
  • 21:45 --> 21:47for some right hairstyles,
  • 21:47 --> 21:48but here's what I would say.
  • 21:48 --> 21:49The hats the best.
  • 21:49 --> 21:51If someone is balding and there's
  • 21:51 --> 21:53a lot of exposed skin, then yeah,
  • 21:53 --> 21:55I think spraying it's a really good idea.
  • 21:55 --> 21:57I don't think that you just want
  • 21:57 --> 21:58to go spraying sunscreen throughout
  • 21:58 --> 22:00your your hair because that's not
  • 22:00 --> 22:01going to be particularly helpful.
  • 22:01 --> 22:04You really want to get it on exposed
  • 22:04 --> 22:06skin and so for all those men out there
  • 22:06 --> 22:09who don't like to wear a hat but do
  • 22:09 --> 22:11have a bald scalp or hair thinning.
  • 22:11 --> 22:13Absolutely protecting it with sunscreen.
  • 22:13 --> 22:16It's very important and will reduce sunburns,
  • 22:16 --> 22:17will reduce ultraviolet damage
  • 22:17 --> 22:19to your skin and will therefore
  • 22:20 --> 22:21reduce you getting skin cancer.
  • 22:22 --> 22:24OK then the next thing
  • 22:24 --> 22:26you said was sunglasses.
  • 22:26 --> 22:29So is there a particular type of
  • 22:29 --> 22:31sunglasses that you should be wearing?
  • 22:31 --> 22:34Or are dark shades good enough
  • 22:34 --> 22:37or how does that kind of work?
  • 22:37 --> 22:39Yeah, so you actually can develop
  • 22:39 --> 22:42a Melanoma in in the eye.
  • 22:42 --> 22:44And while there's many different
  • 22:44 --> 22:46genetic and environmental risk
  • 22:46 --> 22:48factors that are important there,
  • 22:48 --> 22:49getting ultraviolet damage
  • 22:49 --> 22:51is clearly one of them.
  • 22:51 --> 22:52And so I just tell patients
  • 22:52 --> 22:54to find a pair of sunglasses,
  • 22:54 --> 22:56especially those that have UV protection,
  • 22:56 --> 22:58which many of the nicer brands do.
  • 22:58 --> 23:00And that's that's something that's
  • 23:00 --> 23:03important in addition to the eyes.
  • 23:03 --> 23:05Another area that's sometimes
  • 23:05 --> 23:06forgotten are the lips,
  • 23:06 --> 23:08and so I do tell patients also
  • 23:08 --> 23:10to don't forget about applying
  • 23:10 --> 23:11sunscreen to the lips,
  • 23:11 --> 23:14and so they're actually are special.
  • 23:14 --> 23:16Lip balms that have sunscreen in them,
  • 23:16 --> 23:17which patients can buy
  • 23:18 --> 23:21that's interesting. I didn't know that.
  • 23:21 --> 23:24What about getting back to the glasses part?
  • 23:24 --> 23:27UM, OK, fine, you can wear shades
  • 23:27 --> 23:30when you're not in the pool,
  • 23:30 --> 23:31but if you're jumping into a
  • 23:31 --> 23:34pool or a lake, let me tell you.
  • 23:34 --> 23:35Swimming with glasses on
  • 23:35 --> 23:37is a little bit tricky.
  • 23:37 --> 23:39So what do you do then?
  • 23:41 --> 23:44If you are not going to wear sunglasses,
  • 23:44 --> 23:46then you know applying sunscreen
  • 23:46 --> 23:48to your face, and again,
  • 23:48 --> 23:51you know you can totally go in the pool
  • 23:51 --> 23:54with a really nice hat and you know if
  • 23:55 --> 23:57you're worried about it getting wet,
  • 23:58 --> 24:01you can totally take it off.
  • 24:01 --> 24:03Apply sunscreen and then reapply it,
  • 24:03 --> 24:04but I told my patients we
  • 24:04 --> 24:06have to do the best we can.
  • 24:06 --> 24:07You want to protect your skin.
  • 24:07 --> 24:09We have so many different strategies
  • 24:09 --> 24:11that we can use sunscreen.
  • 24:11 --> 24:12Had some protective clothes
  • 24:12 --> 24:14and a lot of my patients.
  • 24:14 --> 24:16Once they develop a skin cancer,
  • 24:16 --> 24:18they're saying to themselves, well,
  • 24:18 --> 24:19that's it. I don't want anymore.
  • 24:19 --> 24:21And so when they go in the
  • 24:21 --> 24:22pool you better believe it.
  • 24:22 --> 24:23They have a hat on.
  • 24:23 --> 24:25They have a sun protective clothing
  • 24:25 --> 24:27on they look like scuba divers
  • 24:27 --> 24:29and and I think that's great
  • 24:30 --> 24:32so you know in terms of
  • 24:32 --> 24:34really protecting yourself,
  • 24:34 --> 24:36there are now some clothing brands
  • 24:36 --> 24:39that claim to have UV protection
  • 24:39 --> 24:42or they're kind of sun repellent.
  • 24:42 --> 24:45That clothing they're a little bit
  • 24:45 --> 24:47hard to find, but they are available.
  • 24:47 --> 24:49Is that worth it or is
  • 24:49 --> 24:51that just over the top?
  • 24:52 --> 24:54So I would never say it's over the top.
  • 24:54 --> 24:57If somebody's really worried about, you know,
  • 24:57 --> 24:59let's say they have had skin cancers,
  • 24:59 --> 25:01they really don't want to get anymore
  • 25:01 --> 25:03skin cancer and so clothing that has
  • 25:03 --> 25:05UPF ultraviolet protective factor.
  • 25:05 --> 25:07Those are great and you
  • 25:07 --> 25:08can order those online.
  • 25:08 --> 25:10You can find them at many different stores,
  • 25:10 --> 25:13but in general, if you're wearing clothing,
  • 25:13 --> 25:14you're wearing a hat.
  • 25:14 --> 25:15If you're wearing,
  • 25:15 --> 25:17you know long sleeve shirt and
  • 25:17 --> 25:20pants that tends to be a very
  • 25:20 --> 25:21good strategy to prevent.
  • 25:21 --> 25:24To protect your skin from UV damage,
  • 25:25 --> 25:28now the other thing while people are
  • 25:28 --> 25:31getting ready to hit the beach this summer,
  • 25:31 --> 25:34some people try to get kind of a head
  • 25:34 --> 25:37start on tanning by visiting their
  • 25:37 --> 25:40local tanning salon. OK or not? OK,
  • 25:40 --> 25:41definitely not. OK,
  • 25:41 --> 25:44so for some reason a lot of my patients
  • 25:44 --> 25:46would tell me that before going on a
  • 25:47 --> 25:49vacation they would get a head start.
  • 25:49 --> 25:51They would get a baseline tan,
  • 25:51 --> 25:52so we absolutely know.
  • 25:52 --> 25:54That especially for young women
  • 25:54 --> 25:56who seem to do this more than
  • 25:56 --> 25:59young men that using tanning beds,
  • 25:59 --> 26:00significantly increases your
  • 26:00 --> 26:02risk of getting Melanoma,
  • 26:02 --> 26:04and so absolutely no.
  • 26:04 --> 26:06No to tanning beds.
  • 26:06 --> 26:08If you want your skin to look tan,
  • 26:08 --> 26:10there's no harm in using
  • 26:10 --> 26:12an artificial Tanner.
  • 26:12 --> 26:14You just don't want to look like Ross from
  • 26:14 --> 26:15friends when he was all orange like a carrot.
  • 26:16 --> 26:17But there's no harm at all for
  • 26:17 --> 26:19using an artificial Tanner.
  • 26:19 --> 26:23OK, so?
  • 26:23 --> 26:25So we've gotten some tips now on
  • 26:25 --> 26:28kind of how to protect ourself and
  • 26:28 --> 26:31and protect ourselves from the sun.
  • 26:31 --> 26:33And we know what to look
  • 26:33 --> 26:36for in terms of Melanoma,
  • 26:36 --> 26:39squamous cell and basal cell cancers.
  • 26:39 --> 26:41But in terms of skin cancer you
  • 26:41 --> 26:43you also mentioned that there
  • 26:43 --> 26:45are things that are a little
  • 26:45 --> 26:46bit outside of our control,
  • 26:46 --> 26:50so genetic factors and so on and so forth.
  • 26:50 --> 26:52How do we know how much baseline
  • 26:52 --> 26:53risk we have?
  • 26:53 --> 26:54And the things that we can't control.
  • 26:56 --> 26:57That's a really great question.
  • 26:57 --> 27:00And so some of the genetic factors
  • 27:00 --> 27:02include our the type of skin,
  • 27:02 --> 27:05hair and nails and eye color that we have.
  • 27:05 --> 27:06So for instance,
  • 27:06 --> 27:09patients that have very white skin,
  • 27:09 --> 27:11lots of freckles, light hair like
  • 27:11 --> 27:14blonde or red hair, light eyes.
  • 27:14 --> 27:16Those are patients that we know
  • 27:16 --> 27:19have a far greater risk of burning.
  • 27:19 --> 27:20And these are also the patients that have
  • 27:20 --> 27:23a far greater risk of getting skin cancer.
  • 27:23 --> 27:25If a patient has many moles on their body,
  • 27:25 --> 27:28we also know that having over 100 moles
  • 27:28 --> 27:30and atypical appearing malls can increase
  • 27:30 --> 27:33your risk for developing Melanoma.
  • 27:33 --> 27:34So those are some of the things
  • 27:34 --> 27:36that we really can't control.
  • 27:36 --> 27:36In addition,
  • 27:36 --> 27:38we also know that genetics
  • 27:38 --> 27:40is important here as well.
  • 27:40 --> 27:43So if we have a strong genetic history
  • 27:43 --> 27:45of others who have skin cancer,
  • 27:45 --> 27:46that could also increase your risk.
  • 27:47 --> 27:49Great one last question.
  • 27:49 --> 27:53You did mention that one of the things.
  • 27:53 --> 27:55That we should be thinking about
  • 27:55 --> 27:57is getting regular skin checks.
  • 27:57 --> 28:00So how do we know whether we should
  • 28:00 --> 28:02get a skin check who we should
  • 28:02 --> 28:05go and see about that and how
  • 28:05 --> 28:07often that should be done? Advice?
  • 28:08 --> 28:10Yes, so in general not everybody
  • 28:10 --> 28:12needs to get his skin check.
  • 28:12 --> 28:14Get his skin, check a total body skin
  • 28:14 --> 28:16check by a board certified dermatologist.
  • 28:16 --> 28:18If you're somebody who has a person
  • 28:18 --> 28:20or family history of skin cancer.
  • 28:20 --> 28:22If you think that you're someone
  • 28:22 --> 28:25who has these genetic or phenotypic
  • 28:25 --> 28:27risks of developing skin cancer.
  • 28:27 --> 28:29And if you have something on your
  • 28:29 --> 28:31skin that you're concerned about,
  • 28:31 --> 28:32definitely see a dermatologist.
  • 28:33 --> 28:35Doctor Jonathan Leventhal is an
  • 28:35 --> 28:37assistant professor of dermatology
  • 28:37 --> 28:39at the Yale School of Medicine.
  • 28:39 --> 28:41If you have questions,
  • 28:41 --> 28:43the address is canceranswers@yale.edu
  • 28:43 --> 28:45and passed editions of the program
  • 28:45 --> 28:48are available in audio and written
  • 28:48 --> 28:49form at yalecancercenter.org.
  • 28:49 --> 28:51We hope you'll join us next week to
  • 28:51 --> 28:53learn more about the fight against
  • 28:53 --> 28:54cancer here on Connecticut Public
  • 28:54 --> 28:57radio funding for Yale Cancer Answers
  • 28:57 --> 29:00is provided by Smilow Cancer Hospital.