What We Do

We process and read more than 70,000 specimens per year. We also provide pathologist-performed fine-needle aspiration service at the request of physicians within Yale New Haven Hospital.

Cytoprep Lab

We offer complete cytopathology consult services including preparation, analysis and ancillary studies for cervical cancer and other diseases. Since the introduction of the Pap smear test for the early detection of cervical cancer in 1941, there has been a 70 percent reduction in the cervical cancer mortality rate, the most significant reduction of mortality attributable to any modern medical test. The latest developments in cervical cancer detection technology promise to reduce this rate even further.

Pap Smear FAQs

How do I prepare for the test?

Tell your health care provider if you’ve had a prior abnormal Pap smear; if you might be pregnant; and if you are taking any medications, including birth control pills. Avoid douching, using tampons, having intercourse, and tub bathing 24 hours before the test. Empty your bladder just before the test.

What do the results mean?

  • Negative means that no abnormalities were found.
  • Atypical Squamous Cells of Undetermined Significance or ASCUS indicates abnormal findings, which may be related to a benign or a precancerous condition. Follow-up is recommended.
  • Low Grade Squamous Intraepithelial Lesion indicates a precancerous condition.
  • High Grade Squamous Intraepithelial Lesion indicates a precancerous condition.
  • Carcinoma indicates a malignant lesion.