Quit Smoking

This information is useful for children, adults, and older adults
Why Yale Medicine?
  • Yale Medicine scientists are conducting some of the most advanced research on tobacco use in the world.
  • Our research includes clinical trials for which you may be eligible.
  • Our experts are highly knowledgeable about factors that make certain people more susceptible to tobacco addiction.

If you're having trouble trying to quit smoking, there is a good reason. Studies have shown that smoking can be harder to quit than opiates, cocaine, or alcohol. But the effort is worth it. There are more than 480,000 tobacco-related deaths in the United States each year. Tobacco is this country's most preventable cause of death and disease.

While quitting tobacco use may require several attempts, success is possible, often with the help of nicotine-replacement therapies and counseling. Yale Medicine is a leader in tobacco dependence treatment and research, with research centers that investigate new therapies for smoking cessation, often through clinical trials.

Many smokers like to say they are not dependent on tobacco and can quit whenever they want. Don't be so sure. Here are some signs that you may be in deeper than you realize: 

  • Difficulty cutting down or stopping tobacco use
  • Continuing to smoke, despite smoking-related health symptoms 
  • Giving up social or recreational activities in places where smoking is prohibited 
  • Withdrawal symptoms if you stop temporarily, such as craving tobacco products, anxiety, restlessness, irritability, depressed mood, increased hunger, insomnia, concentration problems and bowel problems

Clinical Trials

New treatments for many conditions are tested in clinical trials, which ultimately bring lifesaving new drugs and devices to the patients who need them most. By participating in a clinical trial, you may get access to the most advanced treatments for your condition, and help determine their benefits for future patients.