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Attention Deficit Hyperactivity Disorder (ADHD)

  • A neurodevelopmental condition involving differences in how the brain develops and functions, affecting attention, impulse control, and activity level
  • Symptoms include difficulty sustaining attention, starting and completing tasks, staying organized, managing impulses, and, in some children, high levels of activity or impulsivity
  • Treatment includes medication, educational supports and accommodations, behavioral strategies, and therapy
  • Involves Child Study Center, Developmental & Behavioral Pediatric Program, Psychiatry

Attention Deficit Hyperactivity Disorder (ADHD)

Overview

A diagnosis of attention deficit hyperactivity disorder (ADHD) can feel overwhelming for families. With a thorough evaluation and treatment tailored to each child’s needs, children with ADHD can function well and thrive at home, at school, and socially.

ADHD is a chronic neurodevelopmental condition that affects a child’s ability to focus, sustain attention, complete tasks, regulate impulses, and manage activity level. The term neurodevelopmental refers to differences in brain development and maturation, which typically begin before birth or during early childhood. In this sense, ADHD reflects how the brain is wired rather than issues of motivation, effort, or parenting.

According to recent data from the United States, approximately 10% to 11% of children between the ages of four and 17 have been diagnosed with ADHD. Although ADHD is considered a lifelong condition from a neurobiological (related to how the brain works) perspective, the way symptoms present and the degree to which they interfere with daily life often change over time, particularly with appropriate support and treatment. The condition can significantly affect how a child functions academically, socially, and at home.

“ADHD diagnoses have been on a steady rise over the years,” says Ayotunde Ayobello, MD, a child psychiatrist at the Yale Medicine Child Study Center. “This does not mean ADHD itself is becoming more common. Rather, increased awareness, better recognition, and improved access to care have allowed us to identify it more accurately.” He adds that academic and behavioral expectations are far greater than in previous decades. Children who may have managed adequately in the past may now struggle under increased demands, bringing symptoms to light earlier.

What causes ADHD?

ADHD is best understood as a biological, neurodevelopmental condition with strong genetic influences.

Brain research has identified differences in how certain neurotransmitter systems function in individuals with ADHD, particularly those involving dopamine and norepinephrine. Neurotransmitter systems are brain chemicals (including dopamine and norepinephrine) that carry messages between nerve cells. Dopamine plays a critical role in motivation, how the brain responds to rewards, regulating attention, and starting tasks. Research suggests that individuals with ADHD often have less efficient dopamine signaling in brain networks responsible for sustaining focus, initiating tasks, and completing them.

Studies also show that certain factors can increase a child’s likelihood of developing ADHD. These include exposure to tobacco or alcohol during pregnancy, being born prematurely or at a low birth weight, and experiencing significant early-life stress or neglect. ADHD also tends to run in families, and many children with the condition have a parent or close relative with similar traits. At the same time, some children develop ADHD even in the absence of any clearly identifiable risk factors.

What are the symptoms of ADHD in a child?

The core symptoms of ADHD include difficulty sustaining attention, challenges with task initiation and completion, distractibility, organizational difficulties, and, in some children, hyperactivity or impulsivity. Because many children display these behaviors occasionally, it can be difficult to determine whether a child’s behavior reflects typical development or ADHD.

“This can be confusing,” says Dr. Ayobello. “A child may be able to pay attention and focus intensely on preferred activities, such as playing video games, but struggle to complete homework or make frequent mistakes on routine tasks.” Difficulty with motivation to start and sustain non-preferred tasks is a hallmark feature of ADHD and is closely tied to how the brain’s reward and dopamine systems function.

There are also less obvious consequences of ADHD. “A child who struggles with ADHD may get in trouble more often or be labeled as ‘problematic,’” explains Dr. Ayobello. “Over time, this can contribute to low self-esteem, diminished confidence, and a pessimistic view of their abilities and sense of self.”

How is ADHD diagnosed?

“ADHD is not diagnosed with a single test,” says Dr. Ayobello. “There is no blood test, brain scan, or quick screening tool that can diagnose ADHD. Instead, diagnosis relies on a comprehensive clinical evaluation that examines behavior patterns over time and across settings.”

A thorough evaluation begins with gathering detailed information from the child and caregivers about current symptoms, when symptoms began, and the settings in which they occur, including home, school, and social environments. Clinicians also assess how symptoms affect daily functioning, such as academic performance, relationships, and everyday responsibilities.

Because ADHD requires symptoms to be present in two or more settings, clinicians often seek input from teachers, school staff, coaches, or other adults who regularly observe the child. This helps determine whether symptoms are consistent and interfering with daily life rather than limited to specific situations.

It is also essential to consider whether other conditions, such as anxiety, learning disorders, mood difficulties, or sleep problems, may be contributing to attention or behavioral challenges. Rating scales and, when appropriate, neuropsychological testing (special tests that measure thinking, memory, and learning skills) can provide additional insight into attention, executive functioning (skills such as planning, organizing, and managing tasks), memory, processing speed (how quickly the brain understands and responds to information), and learning.

How is ADHD treated?

When ADHD is properly diagnosed, medication can be a highly effective component of treatment. Finding the right medication and the right dose often requires careful monitoring and adjustment. Stimulant medications are the most commonly prescribed treatments, although non-stimulant options can also be effective for some children. These medications work by improving the efficiency of dopamine and norepinephrine signaling in brain circuits involved in attention, impulse control, and self-regulation.

“Some people worry that stimulant medications may increase the risk of addiction later in life,” says Dr. Ayobello. “Research shows the opposite. When ADHD is treated appropriately, individuals are less likely to seek stimulation in unhealthy or maladaptive ways.”

Medication alone is rarely sufficient. Effective treatment often includes educational supports and accommodations, behavioral strategies, and psychotherapeutic interventions (treatments involving talk therapy or counseling). Many children benefit from cognitive behavioral therapy (CBT), play-based approaches, or skills-focused therapies that help them develop organization, emotional regulation, and coping strategies that support success at school and in social settings.

What can parents do to help a child with ADHD reach her full potential?

Because no two children with ADHD are the same, parents and caregivers play an important role in identifying and leveraging a child’s strengths. Many children with ADHD are highly intelligent, creative, and energetic, but require tailored strategies to help them stay engaged and motivated.

“The ADHD brain responds particularly well to tasks that include novelty, interest, challenge, or a sense of urgency,” says Dr. Ayobello. Parents can help by breaking assignments and projects into manageable steps, providing structure and reminders, and helping children stay organized. A quiet, low-distraction environment for homework and studying can also make a meaningful difference.

What makes Yale Medicine's approach to the diagnosis and treatment of children with ADHD unique?

Yale Medicine Child Study Center has been at the forefront of ADHD research and clinical innovation for decades, playing a central role in shaping how the condition is understood, diagnosed, and treated today. Leaders in the field, including Andrés S. Martin, MD, PhD, and Michael Bloch, MD, MS, have conducted influential research that directly informs current best practices in child and adolescent ADHD care. The center has also contributed to pioneering work on non-stimulant medication options for children who do not respond well to traditional stimulant treatments.