Trial of Amlenetug in Patients with Multiple System Atrophy (MASCOT)
- Study HIC#:2000038505
- Last Updated:12/19/2025
The MASCOT Trial aims to see if the investigational trial drug (Lu AF82422) is effective and safe in slowing the disease progression in people living with multiple system atrophy (MSA). The clinical trial will compare the investigational trial drug to a placebo (inactive medication). The investigational trial drug is given by intravenous (IV, or through a vein) infusion once every 4 weeks.
Contact Us
For more information about this study, including how to volunteer, contact:
MaryClare Kelly
- Phone Number: 1-203-903-2698
Help Us Discover!
You can help our team find trials you might be eligible for by creating a volunteer profile in MyChart. To get started, create a volunteer profile, or contact helpusdiscover@yale.edu, or call +18779788343 for more information.
Eligibility Criteria
· 40-75 years of age
· Have been diagnosed with MSA and it has been less than 5 years from the time of onset of MSA symptoms related to abnormal body movement
· Have a reliable caregiver who will be available throughout the trial to complete caregiver observer questionnaires
