Phase III
Inhibition of Sterile Inflammation by Digoxin
- Study HIC#:2000025289
- Last Updated:02/02/2024
A 3-week study trial to test the effect of Digoxin on immune system. You will be asked to take digoxin (1.5 or 3 mcg/kg) or placebo for 3 weeks, weekly blood work up and EKG will be done. This will test if administering digoxin orally to healthy subjects results in a reduction in innate immune inflammatory responses in the peripheral blood.
- Age18 years - 70 years
- GenderBoth
Contact Us
For more information about this study, including how to volunteer, contact:
Fatima Jamshed
Help Us Discover!
You can help our team find trials you might be eligible for by creating a volunteer profile in MyChart. To get started, create a volunteer profile, or contact helpusdiscover@yale.edu, or call +18779788343 for more information.
Eligibility Criteria
Eligibility Criteria
Inclusion Criteria:
- All healthy volunteers >18 and <70 years old
Exclusion Criteria:
- Autoimmune liver disease, chronic viral hepatitis, hepatocellular carcinoma, portal vein thrombosis, extrahepatic terminal disease, pregnancy, treatment with prednisone and pentoxifylline in the last 3 days, active alcohol abuse, AST, ALT and total bilirubin > 3 mg/dl in 3 months, alcoholic hepatitis.
