Skip to Main Content
Phase COVID-Pilot

Neural correlates of vaporized cannabis use

  • Study HIC#:2000027521
  • Last Updated:07/30/2021

To examine cognitive control and reward processing in young adults who use vaporized CBD and THC products using EEG and fMRI. We aim to determine whether long term use of these products, as reported by participants, impacts functional correlates of behavioral inhibition and reward processing in young adults

  • Age21 years - 50 years
  • GenderBoth
  • Start Date03/06/2020
  • End Date04/01/2022

Trial Purpose and Description

To examine cognitive control and reward processing in young adults who use vaporized CBD and THC products using EEG and fMRI. We aim to determine whether long term use of these products, as reported by participants, impacts functional correlates of behavioral inhibition and reward processing in young adults

Eligibility Criteria

We are interested in examining how vaping CBD vs THC may affect cognition, such as how you are able to do certain tasks. Participants will visit the laboratory twice to perform tasks while EEG or fMRI is recorded. 

Eligibility criteria: Adults 21-50 who vape primarily CBD or THC and healthy non-using controls.
Exclusion criteria:
1. A serious neurological or endocrine disorder or any medical condition or treatment known to affect the brain.
2. A medical condition that requires treatment with a medication with psychotropic effects.
3. Occurrence of a stroke, as reported by the participant during screening.
4. Any contraindications to MRI scanning (i.e., metal implants, pacemakers, etc.)
5. History of loss of consciousness (LOC) for longer than 30 minutes or LOC with any neurological sequelae.
6. DSM-5 criteria for intellectual disability.
7. Current or a history of active neurological or psychiatric disorders, such as psychosis, bipolar illness, organic brain disease, dementia or current alcohol or substance disorders other than marijuana products
8. Pregnancy, as indicated by initial screening or verbal confirmation of pregnancy at one of the two testing sessions.
9. (Controls only) any reports or indications (via drug testing) of illicit drug or nicotine use. 10. Planning to quit vaping with a set goal or time for quit attempt
Contact information: Cody Bartz, cody.bartz@yale.edu or call (203) 785-5840 

Principal Investigator

For more information about this study, contact:

Or contact the Help us Discover team on: