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Phase I

Effects of E-Cigarette Flavors on Adults TCORS 2.0

  • Study HIC#:2000023077
  • Last Updated:07/15/2021

This study looks at the effects of flavors when administered with nicotine in e-cigarettes in younger and older adult cigarette smokers. Complete our brief survey to see if you may be eligible: YaleVapeStudy.com

  • Age21 years - 50 years
  • GenderBoth
  • Start Date06/29/2018
  • End Date08/31/2023

Trial Purpose and Description

Primary Aim: Examine the influence of flavors (sweet, cool, tobacco) on reward (liking/wanting) from e-cigs containing one of two nicotine concentrations (6 mg/ml, 18 mg/ml; that vary in harshness), among younger and older adult combustible tobacco users following acute tobacco abstinence.

Eligibility Criteria

Inclusion Criteria:

  • Ages 21-50 years
  • Able to read and write 
  • Not seeking treatment to stop smoking

Exclusion Criteria:

  • Any significant current medical or psychiatric condition
  • Known sensitivity to propylene glycol 
  • Pregnant or lactating females

Principal Investigator

Sub-Investigators

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