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Phase III

Cardiac Sarcoidosis Multi-Center Randomized Controlled Trial (CHASM CS- RCT)

  • Study HIC#:2000027643
  • Last Updated:12/22/2022

The purpose of this study is to compare the effects of low dose prednisone combined with methotrexate to see if it will be as effective, and better tolerated than the standard dose of prednisone alone in the treatment of cardiac sarcoidosis.

  • Age18 years and older
  • GenderBoth
  • Start Date12/16/2020
  • End Date12/31/2022

Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

  • Cardiac sarcoidosis with positive biopsy and/or Chest CT with features of sarcoidosis
  • ¬†Age >/= 18

Exclusion Criteria:

  • Current or recent treatment for sarcoidosis
  • Currently taking Methotrexate or Prednisone for another health condition
  • Cannot take either drug
  • Pregnancy

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