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Phase III

Cardiac Sarcoidosis Multi-Center Randomized Controlled Trial (CHASM CS- RCT)

  • Study HIC#:2000027643
  • Last Updated:03/17/2023

The purpose of this study is to compare the effects of low dose prednisone combined with methotrexate to see if it will be as effective, and better tolerated than the standard dose of prednisone alone in the treatment of cardiac sarcoidosis.

  • Age18 years and older
  • GenderBoth

Contact Us

For more information about this study, including how to volunteer, contact:

Arben Ademi

Help Us Discover!

You can help our team find trials you might be eligible for by creating a volunteer profile in MyChart. To get started, create a volunteer profile, or contact helpusdiscover@yale.edu, or call +18779788343 for more information.

Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

  • Cardiac sarcoidosis with positive biopsy and/or Chest CT with features of sarcoidosis
  • ¬†Age >/= 18

Exclusion Criteria:

  • Current or recent treatment for sarcoidosis
  • Currently taking Methotrexate or Prednisone for another health condition
  • Cannot take either drug
  • Pregnancy

For more information about this study, including how to volunteer, contact: